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preeclampsia in postpartum

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https://www.readbyqxmd.com/read/28095254/maternal-psychological-distress-during-pregnancy-does-not-increase-the-risk-for-adverse-birth-outcomes
#1
Aleksandra Staneva, Alina Morawska, Fiona Bogossian, Anja Wittkowski
Maternal psychological distress during pregnancy is a potential risk factor for various birth complications. This study aimed to explore psychological factors associated with adverse birth outcomes. Symptoms of psychological distress, individual characteristics, and medical complications were assessed at two time points antenatally in 285 women from Australia and New Zealand; birth outcomes were assessed postpartum, between January 2014 and September 2015. Hierarchical multiple regression analyses were conducted to examine the relation of psychological distress to adverse birth outcomes...
January 17, 2017: Women & Health
https://www.readbyqxmd.com/read/28090230/epidemiology-of-pregnancy-associated-icu-utilization-in-texas-2001-2010
#2
Lavi Oud
BACKGROUND: ICU admission is uncommon among obstetric patients. Nevertheless, the epidemiology of ICU utilization is considered to be a useful proxy for study of severe maternal morbidity and near-miss events. However, there is paucity of population-level studies in obstetric patients in the United States. METHODS: The Texas Inpatient Public Use Data File and state-based reports were used to identify pregnancy-associated hospitalizations and those involving admission to ICU (n = 158,410) for the years 2001 - 2010...
February 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28069474/heart-failure-in-late-pregnancy-and-postpartum-incidence-and-long-term-mortality-in-sweden-1997-2010
#3
Anders Barasa, Annika Rosengren, Tatiana Zverkova Sandström, Lars Ladfors, Maria Schaufelberger
AIMS: Heart failure (HF) in late pregnancy and postpartum (HFPP) of which peripartum cardiomyopathy (PPCM) comprises the larger part, is still a rare occurrence in Sweden. Population-based data are scarce. Our aim was to characterise HFPP and determine the incidence and mortality in a Swedish cohort. METHODS AND RESULTS: Through merging data from the National Inpatient, Cause of Death, and Medical Birth Registers, we identified ICD-10 codes for HF and cardiomyopathy, within 3 months before delivery up to 6 months postpartum...
January 6, 2017: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/28031980/obesity-epidemic-impact-from-preconception-to-postpartum
#4
REVIEW
Hind N Moussa, Mesk A Alrais, Mateo G Leon, Elizabeth L Abbas, Baha M Sibai
The obesity epidemic is on the rise throughout the USA and the world. Not only does it affect the general population but it also specifically poses unique threats to a woman's life in the antepartum, peripartum and postpartum periods. An increased BMI is associated with worse perinatal outcomes, including higher rates of preeclampsia (and other hypertensive disorders), macrosomia, other neonatal morbidities and gestational diabetes. Isolated maternal obesity and additional maternal diabetes predispose the infant to potential adult disease through fetal programming...
September 2016: Future Science OA
https://www.readbyqxmd.com/read/28008305/magnesium-sulfate-prevents-placental-ischemia-induced-increases-in-brain-water-content-and-cerebrospinal-fluid-cytokines-in-pregnant-rats
#5
Linda W Zhang, Junie P Warrington
Magnesium sulfate (MgSO4) is the most widely used therapy in the clinic to prevent the progression of preeclampsia, a hypertensive disorder of pregnancy, to eclampsia. Eclampsia, manifested as unexplained seizures and/or coma during pregnancy or postpartum, accounts for ~13% of maternal deaths worldwide. While MgSO4 continues to be used in the clinic, the mechanisms by which it exerts its protective actions are not well understood. In this study, we tested the hypothesis that MgSO4 protects against placental ischemia-induced increases in brain water content and cerebrospinal fluid cytokines...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28004625/pregnancy-perinatal-and-postpartum-complications-as-determinants-of-postpartum-depression-the-rhea-mother-child-cohort-in-crete-greece
#6
K Koutra, M Vassilaki, V Georgiou, A Koutis, P Bitsios, M Kogevinas, L Chatzi
AIMS: Few epidemiological studies evaluated associations between perinatal complications and maternal mood at the early postpartum period and the findings are inconsistent. We aimed at investigating a wide range of complications during pregnancy, at delivery, and at the early postpartum period as determinants of postpartum depression (PPD) at 8 weeks postpartum. METHODS: A total of 1037 women who enrolled in the Rhea mother-child cohort in Crete, Greece participated in the present study...
December 22, 2016: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/27939485/postpartum-physiology-psychology-and-paediatric-follow-up-study-p4-study-study-protocol
#7
Gregory K Davis, Lynne Roberts, George Mangos, Amanda Henry, Franziska Pettit, Anthony O'Sullivan, Caroline S E Homer, Maria Craig, Samuel B Harvey, Mark A Brown
BACKGROUND: Women who have had hypertension in pregnancy are at greater risk of long term cardiovascular disease (CVD). Little is known about their cardiovascular risk postpartum or the effects on the woman's mental health and the outcomes of their infants. In this project we will study the physiological and psychological health of women and the physical health and development of their infants six months, two years and five years after birth. We will establish normal blood pressure (BP) and metabolic function for women who were normotensive in pregnancy and use these to assess women who had gestational hypertension (GH) or preeclampsia (PE)...
October 2016: Pregnancy Hypertension
https://www.readbyqxmd.com/read/27896245/differences-in-clinical-presentation-and-pregnancy-outcomes-in-antepartum-preeclampsia-and-new-onset-postpartum-preeclampsia-are-these-the-same-disorder
#8
Gustavo Vilchez, Luis R Hoyos, Jocelyn Leon-Peters, Moraima Lagos, Pedro Argoti
OBJECTIVE: New-onset postpartum preeclampsia is a poorly defined condition that accounts for a significant percentage of eclampsia cases. It is unclear whether new-onset postpartum preeclampsia is a different disorder from or belongs to the same spectrum of classic antepartum preeclampsia. The objective of this study was to compare the clinical presentation and pregnancy outcomes of antepartum preeclampsia and new-onset postpartum preeclampsia. METHODS: A retrospective study including 92 patients with antepartum preeclampsia and 92 patients with new-onset postpartum preeclampsia was performed...
November 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27892433/efficacy-of-prophylactic-b-lynch-suture-during-lower-segment-caesarian-section-in-high-risk-patients-for-atonic-postpartum-haemorrhage
#9
M Vijayasree
Background Postpartum Haemorrhage causes significant maternal mortality and morbidity all over the world. Active management of the third stage of labour with oxytocics is come into practice. If postpartum haemorrhage is anticipated conservative surgical procedures like B-lynch suture is being applied. Objective To evaluate the effect of elective B-Lynch suture in preventing atonic postpartum haemorrhage during emergency caesarian section with high risk factors for atonicity. Method Forty antenatal women undergoing emergency caesarean section with risk factors for atony of the uterus were selected in our study...
January 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/27887588/longitudinal-reference-ranges-for-maternal-plasma-laeverin-and-its-role-as-a-potential-biomarker-of-preeclampsia
#10
Mona Nystad, Vasilis Sitras, Kari Flo, Christian Widnes, Åse Vårtun, Tom Wilsgaard, Ganesh Acharya
BACKGROUND: Laeverin is a placenta-specific membrane-bound aminopeptidase. In this study we wanted to: 1) serially measure plasma levels of laeverin in healthy women during the second half of pregnancy and postpartum, 2) determine whether laeverin is differently expressed at 22-24 weeks in women who later develop preeclampsia compared to controls, 3) compare laeverin protein expression in placenta and umbilical vein serum in healthy and preeclamptic pregnancies at birth. METHODS: Plasma was obtained serially, approximately every 4-weeks, from 53 healthy women with uncomplicated pregnancies during 22(+0) to 39(+6) weeks of gestation, and at 22-24 weeks from 15 women who later developed preeclampsia...
November 25, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27871550/carbetocin-for-prevention-of-postcesarean-hemorrhage-in-women-with-severe-preeclampsia-a-before-after-cohort-comparison-with-oxytocin
#11
B Nucci, Agm Aya, E Aubry, J Ripart
STUDY OBJECTIVE: The aim of the study was to compare the incidence of the use of additional uterotonics before and after the change of carbetocin to oxytocin for the prevention of postpartum hemorrhage after cesarean delivery in women with severe preeclampsia. DESIGN: This was an observational retrospective before-and-after study. SETTING: Operating room, postoperative recovery area. PATIENTS: Sixty women with severe preeclampsia undergoing cesarean delivery under spinal anesthesia; American Society of Anesthesiologists 3...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27859887/preclinical-atherosclerosis-at-the-time-of-pre-eclamptic-pregnancy-and-up-to-10-years-postpartum-systematic-review-and-meta-analysis
#12
REVIEW
Natasa M Milic, Jelena Milin-Lazovic, Tracey L Weissgerber, Goran Trajkovic, Wendy M White, Vesna D Garovic
OBJECTIVES: Preeclampsia, a pregnancy-specific hypertensive disorder, has been associated with cardiovascular risk factors and vascular changes, such as acute atherosis in placental blood vessels, which are similar to early-stage atherosclerosis. The objective of this study was to determine whether women with preeclampsia have increased atherosclerotic burden, as determined by carotid intima-media thickness (CIMT), when compared to women without preeclampsia. METHODS: We conducted a systematic review and meta-analysis of studies that reported CIMT, a non-invasive, ultrasound-based measure of subclinical atherosclerosis, in women who did vs...
November 18, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27835048/furosemide-in-postpartum-management-of-severe-preeclampsia-a-randomized-controlled-trial
#13
P Veena, Lakshmideepthi Perivela, S Soundara Raghavan
BACKGROUND: Hypertension in the postpartum period is a common phenomenon and is often a cause for concern. Following delivery, fluid that has been sequestered in the extravascular space is mobilized, producing a large auto-infusion of fluid from the extravascular to the intravascular compartment. As a result of this fluid mobilization process, there is an increase in central venous pressure and pulmonary capillary wedge pressure, which might favor the development of pulmonary edema. Thus, diuretics logically might be a better choice as antihypertensive medication in such a scenario...
November 11, 2016: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/27831835/imaging-of-neurologic-conditions-in-pregnant-patients
#14
Sangam Kanekar, Shante Bennett
A number of physiologic, hormonal, immunologic, and hemodynamic changes take place in the maternal body during pregnancy. The majority of these changes are essential for maintaining the normal course of pregnancy. However, these changes may also cause acute or chronic conditions that affect various biologic systems in the mother. In addition, conditions of the central and peripheral nervous systems can cause a variety of neurologic symptoms and complications. Neurologic signs and symptoms in pregnant and postpartum women may be due to the exacerbation of a preexisting medical condition, the initial manifestation of a primary central nervous system-related problem, or a neurologic problem unique to pregnancy and the postpartum period...
November 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/27806675/investigation-of-maternal-psychopathological-symptoms-dream-anxiety-and-insomnia-in-preeclampsia
#15
Orkun Cetin, Pınar Guzel Ozdemir, Zehra Kurdoglu, Hanım Guler Sahin
PURPOSE: The aim of the current study was to investigate the psychopathological symptoms, psycho-emotional state, dream anxiety, and insomnia in healthy, mild and severe preeclamptic postpartum women and their relation to the severity of preeclampsia. MATERIALS AND METHODS: This observational study included forty-five healthy, 41 mild preeclamptic and 44 severe preeclamptic postpartum women. The 90-item Symptom Checklist Revised, Hospital Anxiety and Depression Scale, Insomnia Severity Index, and Van Dream Anxiety Scale were used to evaluate the psychopathological symptoms, psycho-emotional state, insomnia, and dream anxiety of the participants after delivery...
November 2, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27804179/pre-eclampsia-an-important-risk-factor-for-asymptomatic-heart-failure
#16
C Ghossein-Doha, J van Neer, B Wissink, N M Breetveld, L J de Windt, A P J van Dijk, M J van der Vlugt, M C H Janssen, W M Heidema, R R Scholten, M E A Spaanderman
OBJECTIVES: Pre-eclampsia (PE) is associated with both postpartum structural asymptomatic heart disease (i.e. heart failure Stage B (HF-B)) and conventional cardiovascular (CV) risk factors. We aimed to evaluate the extent to which PE, adjusted for conventional CV risk factors, is associated independently with asymptomatic cardiac abnormalities postpartum. METHODS: In this cross-sectional cohort study, 107 formerly pre-eclamptic women and 41 women with uneventful previous pregnancy (controls) were invited for CV risk assessment 4-10 years postpartum...
January 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27802418/high-normal-estimated-glomerular-filtration-rate-in-early-onset-preeclamptic-women-10-years-postpartum
#17
Nina D Paauw, Jaap A Joles, José T Drost, Marianne C Verhaar, Arie Franx, Gerjan Navis, Angela H E M Maas, A Titia Lely
: Women with a history of preeclampsia have a 5- to 12-fold increased risk to develop end-stage kidney disease. Previous observations in small cohorts suggest that former preeclamptic (fPE) women have subtle abnormalities in renal hemodynamics and renal function, which might predispose them to renal failure in later life. In this study, we analyzed renal function in a cross-sectional cohort consisting of former early-onset preeclamptic (fPE, n=339) and former healthy pregnant women (fHP, n=332), overall with a mean age of 39 years at 10 years postpartum...
December 2016: Hypertension
https://www.readbyqxmd.com/read/27786578/oral-labetalol-compared-to-oral-nifedipine-for-postpartum-hypertension-a-randomized-controlled-trial
#18
Kathryn J Sharma, Naomi Greene, Sarah J Kilpatrick
OBJECTIVE: To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension. STUDY DESIGN: This randomized controlled trial conducted between June 2014 and June 2015 included women who delivered at ≥32 weeks' gestation with persistent postpartum hypertension (sustained blood pressure ≥150/100 mmHg) requiring an oral antihypertensive agent...
October 27, 2016: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/27762324/maternal-and-live-birth-outcomes-of-pregnancies-following-assisted-reproductive-technology-a-retrospective-cohort-study
#19
Linling Zhu, Yu Zhang, Yifeng Liu, Runjv Zhang, Yiqing Wu, Yun Huang, Feng Liu, Meigen Li, Saijun Sun, Lanfeng Xing, Yimin Zhu, Yiyi Chen, Li Xu, Liangbi Zhou, Hefeng Huang, Dan Zhang
This study was carried out to explore associations between assisted reproductive technology (ART) and maternal and neonatal outcomes compared with similar outcomes following spontaneously conceived births. We conducted a retrospective cohort study of pregnancies conceived by ART (N = 2641) during 2006-2014 compared to naturally conceived pregnancies (N = 5282) after matching for maternal age and birth year. Pregnancy complications, perinatal complications and neonatal outcomes of enrolled subjects were investigated and analysed by multivariate logistic regression...
October 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27761482/immunology-of-neuromyelitis-optica-during-pregnancy
#20
Vahid Davoudi, Kiandokht Keyhanian, Riley M Bove, Tanuja Chitnis
Anti-aquaporin-4 (AQP4) autoantibody plays a key role in the pathogenesis of neuromyelitis optica (NMO). Studies have shown increased relapse rates in patients with NMO during pregnancy and postpartum. High estrogen levels during pregnancy can increase activation-induced cytidine deaminase expression, which is responsible for immunoglobulin production. Additionally, sex hormones may influence antibody glycosylation, with effects on antibody function. Estrogen decreases apoptosis of self-reactive B cells, through upregulation of antiapoptotic molecules...
December 2016: Neurology® Neuroimmunology & Neuroinflammation
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