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https://www.readbyqxmd.com/read/29778586/comparison-of-an-additional-early-visit-to-routine-postpartum-care-on-initiation-of-long-acting-reversible-contraception-a-randomized-trial
#1
Caitlin Bernard, Leping Wan, Jeffrey F Peipert, Tessa Madden
OBJECTIVE: To investigate whether an early 3-week postpartum visit in addition to the standard 6-week visit increases LARC initiation by 8weeks postpartum compared to the routine 6-week visit alone. STUDY DESIGN: We enrolled pregnant and immediate postpartum women into a prospective randomized, non-blinded trial comparing a single 6-week postpartum visit (routine care) to two visits at 3 and 6weeks postpartum (intervention), with initiation of contraception at the 3-week visit, if desired...
May 17, 2018: Contraception
https://www.readbyqxmd.com/read/29778486/preoperative-radiotherapy-or-chemoradiotherapy-in-rectal-cancer-is-survival-improved-an-update-of-the-nordic-larc-study-in-non-resectable-cancers
#2
Morten Brændengen, Bengt Glimelius
The randomized "Nordic" LARC study compared preoperative long-course radiotherapy alone (RT) or with chemotherapy (CRT) in the most locally advanced/ugly rectal cancers. Despite significantly better local control in the CRT group, no overall survival benefit was seen after 10 years follow-up. The relations between local control and survival are discussed.
May 16, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29771940/unplanned-pregnancies-and-contraceptive-use-among-hiv-positive-women-in-care
#3
Madeline Y Sutton, Wen Zhou, Emma L Frazier
Among 230,360 women with diagnosed HIV in the United States (U.S.), ~ 8,500 give birth annually, and unplanned pregnancies (as with HIV-negative women) are prevalent. However, unplanned pregnancies and contraceptive use among HIV-positive women have been understudied. To examine unplanned pregnancies and contraceptive use among HIV-positive women, we used 2013-2014 data from the Medical Monitoring Project (MMP), an HIV surveillance system that produces national estimates for HIV-positive adults in care in the U...
2018: PloS One
https://www.readbyqxmd.com/read/29768114/differences-in-contraceptive-discontinuation-among-black-and-white-women-evidence-from-the-contraceptive-choice-project
#4
Jenifer E Allsworth, Gina M Secura, Olufemi O Ajibade, Jeffrey F Peipert
OBJECTIVE: We sought to evaluate whether differences in rates of contraceptive discontinuation exist among black and white women receiving contraceptive counseling and no-cost contraception among users of long-acting reversible contraceptive (LARC; intrauterine devices or subdermal implant) and non-LARC (oral contraceptive pills, contraceptive vaginal ring, patch, or injection) methods. MATERIALS AND METHODS: We analyzed data from a prospective cohort study of 7546 non-Hispanic black and white women who participated in the Contraceptive CHOICE Project...
May 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29767284/diagnostic-accuracy-of-mri-in-assessing-tumor-regression-and-identifying-complete-response-in-patients-with-locally-advanced-rectal-cancer-after-neoadjuvant-treatment
#5
Medhat Aker, Darren Boone, Anuradha Chandramohan, Bruce Sizer, Roger Motson, Tan Arulampalam
BACKGROUND: The diagnostic accuracy of Magnetic Resonance Imaging (MRI) in restaging locally advanced rectal cancers (LARC) after neoadjuvant chemo-radio therapy (NCRT) has been under recent scrutiny. There is limited data on the accuracy of MRI and its timing in assessing tumor regression grade (TRG) and in identifying patients with complete response (CR). NCRT seems to cause tissue inflammation and oedema which renders reading the scans difficult for radiologist. AIM: This study aims to assess the accuracy of MRI at different time intervals after NCRT in staging TRG and in identifying CR...
May 16, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29760943/high-parity-predicts-use-of-long-acting-reversible-contraceptives-in-the-extended-postpartum-period-among-women-in-rural-uganda
#6
Ronald Anguzu, Hassard Sempeera, Juliet N Sekandi
Background: The use of implants and Intra-uterine devices (IUD) during the post-partum period is very low in Uganda especially in rural settings. Long-acting reversible contraceptives (LARC) are known to be the most cost-effective for prevention of unintended pregnancy and unsafe abortions. This study aimed at determining the factors associated with long-acting reversible contraceptive use among women in the extended postpartum period in rural Uganda. Methods: We conducted a household-based, cross-sectional study among 400 women in two rural communities in Mityana district, central Uganda...
2018: Contraception and Reproductive Medicine
https://www.readbyqxmd.com/read/29757790/barriers-to-implementation-of-long-acting-reversible-contraception-a-systematic-review
#7
Jessamyn Phillips, Prabjot Sandhu
BACKGROUND AND PURPOSE: Long-acting reversible contraception (LARC) is one of the most effective forms of contraception available. The utilization of LARC remains low despite being recommended by major health organizations such as Centers for Disease Control and Prevention, American Congress of Obstetricians and Gynecologists, American Academy of Pediatrics, American Academy of Family Physicians, and the National Committee for Quality Assurance. Health care professionals play an essential role in the potential increased use of LARC...
April 2018: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29752923/video-compared-to-conversational-contraceptive-counseling-during-labor-and-maternity-hospitalization-in-colombia-a-randomized-trial
#8
Alyssa R Hersh, Luisa F Muñoz, Mónica Rincón, Carolina Alvarez, Jorge E Tolosa, Diva J Moreno, Martha Rubio, Juan C Vargas, Francisco Edna, Nelson Taborda, Maureen K Baldwin
OBJECTIVE: Assess if video-based contraceptive education could be an efficient adjunct to contraceptive counseling and attain the same contraceptive knowledge acquisition as conversation-based counseling. STUDY DESIGN: This was a multi-center randomized, controlled trial examining contraceptive counseling during labor and maternity hospitalization regarding the options of immediate postpartum contraception. At two urban public hospitals, we randomized participants to a structured conversation with a trained counselor or a 14-min video providing the same information...
May 9, 2018: Contraception
https://www.readbyqxmd.com/read/29745309/intraoperative-radiation-therapy-for-rectal-cancer-and-recurrent-intra-abdominal-sarcomas
#9
Thomas Monbailliu, Piet Pattyn, Tom Boterberg, Dirk Van de Putte, Wim Ceelen, Yves Van Nieuwenhove
PURPOSE: The aim of this study was to evaluate the effect of high-dose-rate intraoperative radiation therapy (HDR-IORT) in a multimodality treatment on the local control (LC) and the overall survival (OS) rate in locally advanced rectal cancer (LARC), locally recurrent rectal cancer (LRRC) and recurrent intra-abdominal sarcomas (RS). MATERIALS AND METHODS: A retrospective analysis was performed on 27 patients who were treated with radical resection and HDR-IORT between April 2007 and January 2017...
May 10, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29723394/discontinuation-of-long-acting-reversible-contraception-versus-short-term-hormonal-methods-in-urban-ghana-a-pilot-longitudinal-study
#10
Sarah D Rominski, Abubakar Manu, Ernest Maya, Emmanuel S K Morhe, Vanessa K Dalton
Rates of contraceptive discontinuation are high worldwide,1 including in Ghana.2 Although long-acting reversible contraceptive (LARC) methods are widely available and safe for most women,3 few Ghanaian women use them.4 We aimed to prospectively assess whether discontinuation rates differed among women who adopted a LARC method versus those who adopted a short-term hormonal method. This article is protected by copyright. All rights reserved.
May 3, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29721745/hemoglobin-level-and-xrcc1-polymorphisms-to-select-patients-with-locally-advanced-rectal-cancer-candidate-for-neoadjuvant-chemoradiotherapy-with-concurrent-capecitabine-and-a-platinum-salt
#11
Vincenzo Formica, Michaela Benassi, Giovanna Del Vecchio Blanco, Elena Doldo, Laura Martano, Ilaria Portarena, Antonella Nardecchia, Jessica Lucchetti, Cristina Morelli, Emilia Giudice, Piero Rossi, Alessandro Anselmo, Pierpaolo Sileri, Giuseppe Sica, Augusto Orlandi, Riccardo Santoni, Mario Roselli
A platinum salt (oxaliplatin or cisplatin) is widely used to enhance chemoradation (CRT) response. The potential of cisplatin in neoadjuvant CRT for locally advanced rectal cancer (LARC) has not been fully investigated. Consecutive patients with histologically confirmed LARC were treated with standard pelvic radiotherapy and concurrent cisplatin plus capecitabine (CisCape CRT). Surgery and eight cycles of adjuvant FOLFOX4 were offered to all patients after CRT. Common biochemical variables and key germline genetic polymorphisms were analyzed as predictors of pathological complete response (pCR)...
May 2, 2018: Medical Oncology
https://www.readbyqxmd.com/read/29721045/long-term-outcome-of-oxaliplatin-and-capecitabine-xelox-concomitant-with-neoadjuvant-radiotherapy-and-extended-to-the-resting-period-in-high-risk-locally-advanced-rectal-cancer
#12
Jinghua Tang, Xiaojun Wu, Yanfang Bai, Yuanhong Gao, Wu Jiang, Lingheng Kong, Junzhong Lin, Desen Wan, Zhizhong Pan, Peirong Ding
Purpose: This study aimed at investigating the long-term outcomes of oxaliplatin and capecitabine (XELOX) administered concurrently with preoperative radiation and extended to the resting period in patients with high-risk locally advanced rectal cancer (LARC). Methods: From January 2010 to December 2013, 45 patients were recruited. Study treatment consisted two cycles of XELOX regimen concomitant with preoperative radiation and then followed by an additional cycle of XELOX regimen between completion of neoadjuvant radiotherapy and surgery...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29707156/dose-finding-study-of-oxaliplatin-associated-to-capecitabine-based-preoperative-chemoradiotherapy-in-locally-advanced-rectal-cancer
#13
Gemma Bruera, Mario Di Staso, Pierluigi Bonfili, Antonio Galvano, Rosa Manetta, Gino Coletti, Roberto Vicentini, Stefano Guadagni, Corrado Ficorella, Ernesto Di Cesare, Antonio Russo, Enrico Ricevuto
Introduction: Proper administration timing, dose-intensity, efficacy/toxicity ratio of oxaliplatin added to fluoropyrimidin should be improved to safely perform two-drugs intensive preoperative chemoradiotherapy in locally advanced rectal cancer (LARC). This dose-finding study investigated recommended oxaliplatin dose, safety of oxaliplatin/capecitabine regimen and preliminary activity. Methods: Schedule: oxaliplatin dose-levels, 35-40 mg/m2 /week; capecitabine 825 mg/m2 / twice daily, radiotherapy on rectum/nodes, 50/45 Gy, 45 and 9 boost/45 Gy, in first 5 and subsequent patients, 5 days/week, respectively; for 5 weeks...
April 3, 2018: Oncotarget
https://www.readbyqxmd.com/read/29702080/continuation-of-long-acting-reversible-contraceptives-among-medicaid-patients
#14
Max J Romano, Patryce Toye, Loral Patchen
OBJECTIVE: Our objective was to compare continuation and complication rates of subdermal etonogestrel implants and intrauterine devices (IUDs) using Medicaid insurance claims. STUDY DESIGN: We performed a retrospective cohort study using insurance claims data for 15- to 44-year-old subjects receiving implants or IUDs from 2012 to 2015 in a Medicaid managed care organization in Washington, DC, and Maryland. We performed a planned Kaplan-Meier survival analysis for long-acting reversible contraceptive (LARC) continuation, defined as the absence of a claim for LARC removal, during periods of continuous insurance plan enrollment...
April 24, 2018: Contraception
https://www.readbyqxmd.com/read/29691115/beyond-total-mesorectal-excision-in-locally-advanced-rectal-cancer-with-organ-or-pelvic-side-wall-involvement
#15
A B Mariathasan, K Boye, K E Giercksky, B Brennhovd, H P Gullestad, H L Emblemsvåg, K K Grøholt, S Dueland, K Flatmark, S G Larsen
BACKGROUND: In locally advanced rectal cancer (LARC), beyond total mesorectal excision (bTME) is often necessary to obtain complete resection (R0). The aim of this study was to identify prognostic determinants and compare morbidity and survival in LARC cases requiring bTME or TME surgery. METHOD: Single centre cohort study of LARC cases where all patients received neoadjuvant radiotherapy (n = 332). Data was registered prospectively in an institutional database linked to the National Registry...
April 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29683910/acog-committee-opinion-no-735-adolescents-and-long-acting-reversible-contraception-implants-and-intrauterine-devices
#16
(no author information available yet)
The phenomenon of adolescent childbearing is complex and far reaching, affecting not only the adolescents but also their children and their community. The prevalence and public health effect of adolescent pregnancy reflect complex structural social problems and an unmet need for acceptable and effective contraceptive methods in this population. In 2006-2010, 82% of adolescents at risk of unintended pregnancy were currently using contraception, but only 59% used a highly effective method, including any hormonal method or intrauterine device...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29683905/acog-committee-opinion-no-735-summary-adolescents-and-long-acting-reversible-contraception-implants-and-intrauterine-devices
#17
(no author information available yet)
The phenomenon of adolescent childbearing is complex and far reaching, affecting not only the adolescents but also their children and their community. The prevalence and public health effect of adolescent pregnancy reflect complex structural social problems and an unmet need for acceptable and effective contraceptive methods in this population. In 2006-2010, 82% of adolescents at risk of unintended pregnancy were currently using contraception, but only 59% used a highly effective method, including any hormonal method or intrauterine device...
May 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29661696/use-of-highly-effective-reversible-contraception-in-title-x-clinics-variation-by-selected-state-characteristics
#18
Nathan Hale, Amal Khoury, Michael Smith
BACKGROUND: The use of long-acting reversible contraceptive (LARC) methods, such as intrauterine devices (IUDs) and implants has demonstrated high effectiveness in preventing pregnancy. While LARC use in Title X programs has increased over the past decade, little is know about the extent to which gains are occurring uniformly across states. METHODS: We examined state-level changes in LARC use among Title X clients between 2012 and 2016 using a repeated cross-sectional study design...
April 13, 2018: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/29650419/comparison-of-pathological-complete-response-rates-after-neoadjuvant-short-course-radiotherapy-or-chemoradiation-followed-by-delayed-surgery-in-locally-advanced-rectal-cancer
#19
Sieske Hoendervangers, Alice M Couwenberg, Martijn P W Intven, Wilhelmina M U van Grevenstein, Helena M Verkooijen
INTRODUCTION: Patients with locally advanced rectal cancer (LARC) who are unfit for chemoradiation (CRT), are often offered short-course radiotherapy followed by delayed surgery (SCRT-delay). This entails a lower radiation dose, no chemotherapy and a shorter treatment period. This may lower their chances for complete tumor response and, as such, organ-sparing approaches. The purpose of this study was to compare the pathological complete response (pCR) rates between neoadjuvant CRT and SCRT-delay in patients with LARC in a nationwide database from the Netherlands...
March 23, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29624927/strengthening-youth-friendly-health-services-through-expanding-method-choice-to-include-long-acting-reversible-contraceptives-for-ethiopian-youth
#20
Fariyal F Fikree, Worknesh K Abshiro, Murtala M Mai, Kidest L Hagos, Mengistu Asnake
Despite robust evidence regarding long-acting reversible contraceptive (LARC) low failure rates, immediate return to fertility and safety, LARC uptake among youth is low. We evaluated the effect on contraceptive uptake of training youth-friendly service providers to counsel and provide all contraceptive methods including LARCs in the same unit. A convenience purposive sampling technique was used to select 20 youth friendly health units; ten each in Amhara and Tigray regions, Ethiopia; randomly allocated to the intervention (five) and non-intervention (five) arms...
September 2017: African Journal of Reproductive Health
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