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https://www.readbyqxmd.com/read/28434106/what-do-patients-want-to-know-about-contraception-and-which-method-would-they-prefer
#1
Patricia G Oppelt, Friederike Baier, Christine Fahlbusch, Katharina Heusinger, Thomas Hildebrandt, Christiane Breuel, Ralf Dittrich
PURPOSE: The aim of this study was to determine the extent to which women's choice of contraceptive method depends on the advice received from their gynecologist and whether more intensive counseling might lead to more frequent use of long-acting reversible contraception (LARC). METHODS: A total of 1089 physicians and 18,521 women responded to 32 or 37 questions, respectively, using an online questionnaire. The women were asked about their current use of contraceptive methods, the extent of their satisfaction with them, their satisfaction with the counseling they had received, and whether they wanted to have more information about contraception...
April 22, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28432718/long-acting-reversible-contraception-conflicting-perspectives-of-advocates-and-potential-users
#2
S Rowlands, R Ingham
Worldwide, use of long-acting reversible contraception (LARC) has easily overtaken oral contraceptive use, now with double the prevalence.(1) Rates of LARC (defined as subdermal implants, intrauterine contraceptives and injectables) use are twice as high in the developing world as in the developed world.(1) There are many reasons for this increasing use of LARC, some to do with potential users and some to do with advocates of LARC. This article is protected by copyright. All rights reserved.
April 22, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28427174/association-of-immunologic-markers-from-complete-blood-counts-with-the-response-to-preoperative-chemoradiotherapy-and-prognosis-in-locally-advanced-rectal-cancer
#3
Sung Woo Jung, In Ja Park, Se Heon Oh, Seung-Seop Yeom, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Jung Bok Lee, Chang Sik Yu, Jin Cheon Kim
We investigated retrospectively whether immunologic markers from a complete blood count (CBC) are associated with the responsiveness to preoperative chemoradiotherapy (PCRT) and oncologic outcomes in 984 patients with locally advanced rectal cancer (LARC) who also underwent radical surgery from 2005 to 2013. CBC parameters including the neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) were recorded. Pathologic responses to PCRT were evaluated in the resected specimens using the tumor regression grade system...
February 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28419700/pregnancy-ambivalence-and-long-acting-reversible-contraceptive-larc-use-among-young-adult-women-a-qualitative-study
#4
Jenny A Higgins
CONTEXT: Many young adults are unclear about how much they want to have, or prevent having, a baby. However, pregnancy ambivalence is an underexamined factor in the uptake of long-acting reversible contraceptive (LARC) methods-IUDs and implants-the most effective methods available. METHODS: In 2014, investigators conducted six focus groups and 12 interviews with 50 women aged 18-29 in Dane County, Wisconsin; participants were either university students or community residents receiving public assistance...
April 17, 2017: Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28410832/a-dose-finding-and-biomarker-evaluation-phase-ib-study-of-everolimus-in-association-with-5-fluorouracil-and-pelvic-radiotherapy-as-neoadjuvant-treatment-of-locally-advanced-rectal-cancer-e-larc-study
#5
Fabio Gelsomino, Federica Bertolini, Gabriele Luppi, Andrea Spallanzani, Elisa Pettorelli, Luca Reggiani Bonetti, Bruno Meduri, Gianrocco Manco, Pierfranco Conte, Stefano Cascinu
BACKGROUND: During the past 20 years, considerable improvement has occurred in the treatment of patients with locally advanced rectal cancer (LARC). With the introduction of multimodal treatment, refinements in preclinical staging and improvements in surgical skills, local relapse is no longer the major problem for patients with LARC. However, many patients die of metastatic disease. The present phase Ib study aimed to establish the maximum tolerated dose of everolimus combined with 5-fluorouracil and radiotherapy in patients with LARC...
March 24, 2017: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/28403959/impact-of-the-french-3rd-and-4th-generation-pill-scare-in-women-seeking-termination-of-pregnancy
#6
O Caillot, M Aubry, S Duros, L Boyer, C Van Valenberg, J Levêque, V Lavoué
INTRODUCTION: The aim of this study was to evaluate changes in the contraceptive profile of women seeking termination of pregnancy following the debate on 3rd and 4th generation pills in France in 2012. MATERIALS AND METHODS: Single-center case-control study comparing the attitude to contraception before (between 02/15/2012 and 07/16/2012) and after the debate (between 02/25/2013 and 06/24/2013). RESULTS: A total of 291 patients consulted before and 601 after the debate...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28399923/making-good-on-a-call-to-expand-method-choice-for-young-people-turning-rhetoric-into-reality-for-addressing-sustainable-development-goal-three
#7
Fariyal Fatma Fikree, Catharine Lane, Callie Simon, Gwyn Hainsworth, Patricia MacDonald
BACKGROUND: Investments in the nearly two billion young people, aged 10-24 years, in the world today are necessary to meet global development commitments, specifically the Sustainable Development Goals and Ending Preventable Child and Maternal Deaths. More than 12 million married and unmarried adolescents (aged 15-19) will give birth in 2016. Complications of pregnancy and childbirth are the second leading cause of death among 15-19 year-old women and early childbearing can significantly curtail social and economic prospects for young women...
April 11, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28397971/availability-of-long-acting-reversible-contraception-in-kansas-health-departments
#8
Tawana Evans, Megha Ramaswamy, Catherine L Satterwhite
PURPOSE: Unintended pregnancy persists as a public health problem in the United States. Local health departments (LHDs) could play an important role in preventing unintended pregnancy by promoting and providing long-acting reversible contraception (LARC, intrauterine devices [IUDs] and implants), particularly in rural states that may lack robust family planning service infrastructure. The objective of this study was to determine availability of LARC in LHDs in Kansas. METHODS: From October 2015 to January 2016, LHD administrators in Kansas were contacted to participate in a structured, cross-sectional phone survey assessing LARC availability, staff trained to place LARC, the process for obtaining LARC, and barriers to offering LARC...
April 11, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28388997/barriers-to-health-care-providers-provision-of-long-acting-reversible-contraception-to-adolescent-and-nulliparous-young-women
#9
Brooke Hopkins
Despite recommendations for long-acting reversible contraception (LARC) as a first-line contraceptive method for adolescents and young women, its use in the United States remains low. This integrative review highlights previously unidentified barriers to health care providers' provision of LARC to adolescent and nulliparous young women. Four themes emerged: Appropriateness of Candidates and Contraceptive Safety, Provider Training and Work Setting, Appropriate Resources, and Opportunity. Raising awareness of barriers to LARC use may galvanize providers to find solutions...
April 2017: Nursing for Women's Health
https://www.readbyqxmd.com/read/28387979/prescription-contraception-use-and-adherence-by-women-with-substance-use-disorders
#10
Gillian Griffith, Tara Kumaraswami, Stavroula A Chrysanthopoulou, Kristin M Mattocks, Robin E Clark
BACKGROUND AND AIMS: Unintended pregnancy rates are high among women with substance use disorders (SUDs), which could be partly explained by lower use of and adherence to contraception. We aimed to test: (1) the association of SUD with prescription contraceptive use, contraceptive method selection, and adherence; (2) whether practices participating in the Patient-Centered Medical Home Initiative (PCMHI) had better contraceptive use and adherence for patients with SUD; (3) for differences in the association of SUD with adherence by type of contraceptive used...
April 7, 2017: Addiction
https://www.readbyqxmd.com/read/28383371/long-acting-reversible-contraceptive-placement-among-active-duty-u-s-army-servicewomen
#11
Anne K Erickson, D Alan Nelson, Jonathan G Shaw, Pooja D Loftus, Lianne M Kurina, Kate A Shaw
OBJECTIVE: To quantify uptake of long-acting reversible contraceptives (LARC)-intrauterine devices (IUDs) and hormonal implants-among U.S. Army active-duty female soldiers and identify characteristics associated with uptake. METHODS: This retrospective cohort study used the Stanford Military Data Repository, which includes all digitally recorded health encounters for active-duty U.S. Army soldiers from 2011 to 2014. We analyzed data from women aged 18-44 years to assess rates of LARC initiation using medical billing codes...
May 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28380288/feasibility-and-acceptability-of-introducing-routine-antenatal-contraceptive-counselling-and-provision-of-contraception-after-delivery-the-apples-pilot-evaluation
#12
S T Cameron, A Craig, J Sim, A Gallimore, S Cowan, K Dundas, R Heller, D Milne, F Lakha
OBJECTIVE: To determine the feasibility and acceptability of routine antenatal contraceptive counselling and contraception provision including long acting reversible contraception (LARC) postpartum. DESIGN: Health service research evaluation. SETTING: Community antenatal clinics and hospital maternity settings in National Health Service, Scotland UK. POPULATION: Women booked for antenatal care. METHODS: Contraceptive counselling with a community midwife (22 weeks gestation) and provision of contraception (with facilitated access to LARC methods) prior to discharge from maternity hospital...
April 5, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28376779/factors-influencing-use-of-long-acting-versus-short-acting-contraceptive-methods-among-reproductive-age-women-in-a-resource-limited-setting
#13
Leevan Tibaijuka, Robert Odongo, Emma Welikhe, Wilber Mukisa, Lilian Kugonza, Imelda Busingye, Phelomena Nabukalu, Joseph Ngonzi, Stephen B Asiimwe, Francis Bajunirwe
BACKGROUND: Unplanned pregnancy remains a common problem in many resource-limited settings, mostly due to limited access to modern family planning (FP) services. In particular, use of the more effective long-acting reversible contraceptive (LARC) methods (i.e., intrauterine devices and hormonal implants) remains low compared to the short-acting methods (i.e., condoms, hormonal pills, injectable hormones, and spermicides). Among reproductive-age women attending FP and antenatal care clinics in Uganda, we assessed perceptions and practices regarding the use of modern contraceptive methods...
April 4, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28375776/advances-in-contraception-new-options-for-postpartum-women
#14
Rebecca L Taub, Jeffrey T Jensen
short interval repeat pregnancy increases maternal and neonatal morbidity, and provision of postpartum contraception provides primary protection against these adverse outcomes. Confusion regarding effects on breast feeding and thrombosis risk delaying initiation of contraception in the immediate post-partum interval. Delaying contraception provision until the 6-week postpartum visit misses many women who either do not attend or have resumed ovulation and/or intercourse prior to this visit. Because of this, recent studies have looked into initiation of highly effective contraceptive methods at earlier intervals including immediately postpartum...
May 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28363512/diffusion-weighted-magnetic-resonance-imaging-in-locally-advanced-rectal-cancer-treated-with-neoadjuvant-chemoradiotherapy
#15
F De Felice, A L Magnante, D Musio, M Ciolina, C N De Cecco, M Rengo, A Laghi, V Tombolini
PURPOSE: To analyze diffusion-weighted magnetic resonance imaging (DW-MRI) for treatment response assessment in locally advanced rectal cancer (LARC). PATIENTS AND METHODS: Patients with histologically proven rectal adenocarcinoma, stage II-III disease, were enrolled and underwent surgery following neoadjuvant chemoradiotherapy (nCRT). All patients were referred for a DW-MRI protocol on a 3 Tesla MR-system, consisting of axial T2-weighted and DWI sequences prior (I), during (II) and after (III) nCRT...
March 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28353591/systematic-review-and-meta-analysis-of-preoperative-chemoradiotherapy-with-or-without-oxaliplatin-in-locally-advanced-rectal-cancer
#16
REVIEW
Jiabin Zheng, Xingyu Feng, Weixian Hu, Junjiang Wang, Yong Li
BACKGROUND: Preoperative chemoradiotherapy has become the current standard regimen for locally advanced rectal cancer (LARC). However, the additional benefit of oxaliplatin to preoperative chemotherapy was still controversial. On one hand, oxaliplatin may improve the tumor response rate of even prolong the survival time. On the other hand, it can bring a series of adverse effects. Opinions vary from studies to studies. We aim to perform a meta-analysis to evaluate the efficacy, safety, and long-term survival of oxaliplatin in preoperative chemoradiotherapy for LARC...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28342716/immediate-postpartum-intrauterine-device-and-implant-program-outcomes-a-prospective-analysis
#17
Jennifer L Eggebroten, Jessica N Sanders, David K Turok
BACKGROUND: In-hospital placement of intrauterine devices and contraceptive implants following vaginal and cesarean delivery is increasingly popular and responds to maternal motivation for highly effective postpartum contraception. Immediate postpartum intrauterine device insertion is associated with higher expulsion than interval placement, but emerging evidence suggests that the levonorgestrel intrauterine device may have a higher expulsion rate than the copper intrauterine device. OBJECTIVE: This study evaluated in-hospital provision, expulsion, and 6-month continuation of immediate postpartum copper T380 intrauterine devices, levonorgestrel intrauterine devices, and contraceptive implants...
March 23, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28340500/advanced-practice-registered-nurses-and-long-acting-reversible-contraception
#18
Patricia J Kelly, An-Lin Cheng, Kimberly Carlson, Jacki Witt
INTRODUCTION: Advanced practice registered nurses (APRNs) are in an excellent position to address the high rates of unintended pregnancy in the United States by providing long-acting reversible contraceptives (LARCs). These methods are significant in their effectiveness in preventing pregnancy in individual women and in having population-level effects on unintended pregnancy. The aim of this study was to learn more about APRN practices around long-acting reversible contraception and influences on those practices...
March 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28314318/systemic-inflammatory-response-after-preoperative-chemoradiotherapy-can-affect-oncologic-outcomes-in-locally-advanced-rectal-cancer
#19
In Hee Lee, Soyoon Hwang, Soo Jung Lee, Byung Woog Kang, Dongwon Baek, Hye Jin Kim, Su Yeon Park, Jun Seok Park, Gyu Seog Choi, Jae Chul Kim, Seung Hyun Cho, Jong Gwang Kim
AIM: Systemic inflammatory response (SIR) has been reported to be an important determinant of disease progression and survival in patients with colorectal cancer. This study investigated the prognostic relevance of changes in the platelet count on survival and the predictive value of changes in platelet/lymphocyte ratio (PLR) and neutrophil/lymphocyte ratio (NLR) on the pathological tumor response to preoperative chemoradiotherapy (CRT) in patients with locally advanced rectal cancer (LARC)...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28314302/kras-mutant-status-may-be-associated-with-distant-recurrence-in-early-stage-rectal-cancer
#20
Michail Sideris, Jane Moorhead, Salvador Diaz-Cano, Amyn Haji, Savvas Papagrigoriadis
BACKGROUND/AIM: Total mesorectal excision combined with neo-adjuvant chemoradiotherary (CRT) and adjuvant chemotherapy, has been the standard treatment of locally advanced rectal cancer (LARC). Although TNM (Tumor, Node, Metastasis) classification for malignant Tumors is still the cornerstone in rectal cancer staging, there has been an effort to identify molecular biomarkers with additional prognostic or predictive value. MATERIALS AND METHODS: We retrospectively analyzed molecular biomarkers on prospectively collected histological specimens and clinical data from a cohort of 135 consecutive rectal cancer cases who underwent radical excision in a tertiary center between 2011-2014 (males=87, females=48, age range=22-89 years, mean=64,67 years, SD=13...
March 2017: Anticancer Research
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