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Diffusion weighted

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https://www.readbyqxmd.com/read/28538224/transcortical-sensory-aphasia-after-left-frontal-lobe-infarction-loss-of-functional-connectivity
#1
Miseon Kwon, Woo Hyun Shim, Sang-Joon Kim, Jong S Kim
BACKGROUND: The underlying mechanism of transcortical sensory aphasia (TSA) caused by lesions occurring in the left frontal lobe remains unclear. We attempted to investigate the mechanism with the use of functional MRI (fMRI). METHODS: We studied 2 patients with TSA after a left frontal infarction identified by diffusion-weighted MRI. As control subjects, a patient with transcortical motor aphasia and a healthy normal adult were chosen. The Korean version of Western Aphasia Battery was performed initially and at 3 months post stroke...
May 25, 2017: European Neurology
https://www.readbyqxmd.com/read/28535651/-study-of-susceptibility-weighted-imaging-on-mr-and-pathologic-findings-to-distinguish-benign-or-malignant-soft-tissue-tumor
#2
J Liu, Y Chen, X M Bao, X L Ling, J P Ding, Z K Zhang
Objective: To explore the diagnostic performance of susceptibility weighted imaging (SWI)in distinguishing benign or malignant soft tissue tumor, and to study pathological observation. Methods: Sixty-eight patients with soft tissue tumor, who received no previous treatment or invasive examination, received routine preoperative MRI examination and SWI scanning. The graduation and distribution of intratumoral susceptibility signal intensity(ITSS) and proportion of tumor volume were observed.The pathological results were also included for comparative analysis...
May 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28535640/-study-of-diffusion-weighted-imaging-in-combination-with-conventional-mri-signs-for-inflammation-activity-of-chronic-hepatitis-b
#3
H W Ren, H Y Ye, W M An, J H Dong, Y Liu
Objective: To study the correlation between ADC values of diffusion weighted imaging (DWI) and the pathological grading in inflammation activity of chronic hepatitis B, and combined with conventional MRI features to predict the diagnosis effectiveness. Methods: A total of 142 cases of patients with chronic hepatitis B were selected as inflammatory group in 302 Hospital of PLA from January 2014 to December 2015, while 20 cases of healthy subjects without history of liver disease were chosen as control group...
May 23, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28535120/differentiation-of-recurrent-glioblastoma-from-delayed-radiation-necrosis-by-using-voxel-based-multiparametric-analysis-of-mr-imaging-data
#4
Ra Gyoung Yoon, Ho Sung Kim, Myeong Ju Koh, Woo Hyun Shim, Seung Chai Jung, Sang Joon Kim, Jeong Hoon Kim
Purpose To assess a volume-weighted voxel-based multiparametric (MP) clustering method as an imaging biomarker to differentiate recurrent glioblastoma from delayed radiation necrosis. Materials and Methods The institutional review board approved this retrospective study and waived the informed consent requirement. Seventy-five patients with pathologic analysis-confirmed recurrent glioblastoma (n = 42) or radiation necrosis (n = 33) who presented with enlarged contrast material-enhanced lesions at magnetic resonance (MR) imaging after they completed concurrent chemotherapy and radiation therapy were enrolled...
May 23, 2017: Radiology
https://www.readbyqxmd.com/read/28535000/staging-performance-of-whole-body-dwi-pet-ct-and-pet-mri-in-invasive-ductal-carcinoma-of-the-breast
#5
Onofrio Antonio Catalano, Dania Daye, Alberto Signore, Carlo Iannace, Mark Vangel, Angelo Luongo, Marco Catalano, Mazzeo Filomena, Luigi Mansi, Andrea Soricelli, Marco Salvatore, Niccolo Fuin, Ciprian Catana, Umar Mahmood, Bruce Robert Rosen
The aim of the present study was to evaluate the performance of whole-body diffusion-weighted imaging (WB-DWI), whole-body positron emission tomography with computed tomography (WB-PET/CT), and whole-body positron emission tomography with magnetic resonance imaging (WB-PET/MRI) in staging patients with untreated invasive ductal carcinoma of the breast. Fifty-one women with newly diagnosed invasive ductal carcinoma of the breast underwent WB-DWI, WB-PET/CT and WB-PET/MRI before treatment. A radiologist and a nuclear medicine physician reviewed in consensus the images from the three modalities and searched for occurrence, number and location of metastases...
May 19, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28534322/-value-of-functional-magnetic-resonance-imaging-in-predicting-outcomes-of-neoadjuvant-chemoradiotherapy-in-rectal-cancer
#6
Yishan Yu, Jinbo Yue, Jinming Yu
Rectal cancer is one of the common cancers which poses a threat to the health of mankind. In recent years. Multi-modality treatment strategies for locally advanced rectal cancer improve the treatment efficiency. Accurate prediction of the treatment response after the neoadjuvant chemoradiotherapy (CRT) can guide more suitable treatment strategy. MERCURY study proved the prognostic value of post-CRT standard morphologic MRI(T2-weighted) assessment of tumor regression grade(TRG), and MRI assessment of circumferential resection margin can guide the definitive surgery...
May 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28534182/imaging-children-suffering-from-lymphoma-an-evaluation-of-different-18-f-fdg-pet-mri-protocols-compared-to-whole-body-dw-mri
#7
Julian Kirchner, Cornelius Deuschl, Bernd Schweiger, Ken Herrmann, Michael Forsting, Christian Buchbender, Gerald Antoch, Lale Umutlu
OBJECTIVES: The objectives of this study were to evaluate and compare the diagnostic potential of different PET/MRI reading protocols, entailing non-enhanced / contrast-enhanced and diffusion-weighted (18)F-FDG PET/MR imaging and whole-body diffusion-weighted MRI for lesion detection and determination of the tumor stage in pediatric lymphoma patients. METHODS: A total of 28 (18)F-FDG PET/MRI datasets were included for analysis of four different reading protocols: (1) PET/MRI utilizing sole unenhanced T2w and T1w imaging, (2) PET/MRI utilizing additional contrast enhanced sequences, (3) PET/MR imaging utilizing unenhanced, contrast enhanced and DW imaging or (4) WB-DW-MRI...
May 22, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28534163/differentiating-metastatic-from-nonmetastatic-lymph-nodes-in-cervical-cancer-patients-using-monoexponential-biexponential-and-stretched-exponential-diffusion-weighted-mr-imaging
#8
Qingxia Wu, Dandan Zheng, Ligang Shi, Mingbo Liu, Meiyun Wang, Dapeng Shi
OBJECTIVES: To determine the diagnostic value of monoexponential, biexponential and stretched exponential models for identifying lymph nodes (LNs) in patients with cervical cancer. MATERIALS AND METHODS: Fifty female patients with cervical cancer underwent preoperative magnetic resonance imaging. The diffusion parameters of the LNs were calculated by fitting the values to monoexponential, biexponential and stretched exponential models and were compared between the metastatic and non-metastatic LN groups...
May 22, 2017: European Radiology
https://www.readbyqxmd.com/read/28533626/nonhealing-progressive-stress-fractures-of-the-foot-in-a-13-year-old-basketball-player-is-vitamin-k-deficiency-a-risk-factor
#9
Meral Bayramoğlu, Nuray Ünlütürk
[Purpose] To report an adolescent male basketball player with nonhealing stress fractures of the foot and discuss the probable factors. [Subject and Methods] A 13-year-old basketball player presented with right foot pain. He had been playing basketball for three years and practicing 5 days/week. He denied any increase in daily training intensity. Magnetic resonance imaging confirmed stress fractures of the cuboid and cuneiform, with mild edema of the soft tissues between the tarsal bones and tenosynovitis of the flexor hallucis and flexor digitorum longi...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28533118/white-matter-alterations-at-pubertal-onset
#10
Sila Genc, Marc L Seal, Thijs Dhollander, Charles B Malpas, Philip Hazell, Timothy J Silk
Recent neurodevelopmental research supports the contribution of pubertal stage to local and global grey and white matter remodelling. Little is known, however, about white matter microstructural alterations at pubertal onset. This study investigated differences in white matter properties between pre-pubertal and pubertal children using whole brain fixel-based analysis (FBA) of the microscopic density and macroscopic cross-section of fibre bundles. Diffusion-weighted imaging data were acquired for 74 typically developing children (M=10...
May 19, 2017: NeuroImage
https://www.readbyqxmd.com/read/28530536/leuprolide-acetate-release-study-from-%C3%AE-irradiated-plga-based-in-situ-forming-system
#11
Mona Shapourgan, Hamid Mobedi, Nasrin Sheikh, Aliasghar Behnamghader, Arezou Mashak
It is well known that the properties of polymers can be altered by exposure to γ- ray. γ-irradiation has been used as a sterilization method for biodegradable polymeric drug delivery devices, and its drug release profile must not be significantly changed. In this study, the effect of γ-irradiation with 8 kGy doses on the release profile of leuprolide acetate from PLGA-based in situ forming system was evaluated. PLGA-based in situ forming systems were prepared by injecting some specific amount of irradiated solution of PLGA /NMP containing drug into a buffer phosphate pH 7...
March 28, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28530107/leptomeningeal-carcinomatosis-in-a-young-patient-with-obstructive-colorectal-signet-ring-cell-adenocarcinoma
#12
Alejandro Lusilla, Jorge de Tomás
We present the case report of a twenty-five-year-old Moroccan male patient who suffered from leptomeningeal carcinomatosis related to a signet-ring cell carcinoma of the rectum. He presented to the emergency department with abdominal pain, constipation, weight loss and rectal bleeding. The rectal examination showed a rectal tumor and a CT scan revealed a large bowel obstruction due to rectal diffuse thickening. An emergency transverse colostomy was performed, with a rectal biopsy and a cytological sample collection...
May 22, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28528586/white-matter-connectivity-disruptions-in-early-and-chronic-schizophrenia
#13
M A Di Biase, V L Cropley, B T Baune, J Olver, G P Amminger, C Phassouliotis, C Bousman, P D McGorry, I Everall, C Pantelis, A Zalesky
BACKGROUND: White matter disruptions in schizophrenia have been widely reported, but it remains unclear whether these abnormalities differ between illness stages. We mapped the connectome in patients with recently diagnosed and chronic schizophrenia and investigated the extent and overlap of white matter connectivity disruptions between these illness stages. METHODS: Diffusion-weighted magnetic resonance images were acquired in recent-onset (n = 19) and chronic patients (n = 45) with schizophrenia, as well as age-matched controls (n = 87)...
May 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28528319/quantitative-dla-based-compressed-sensing-for-t1-weighted-acquisitions
#14
Pavel Svehla, Khieu-Van Nguyen, Jing-Rebecca Li, Luisa Ciobanu
High resolution Manganese Enhanced Magnetic Resonance Imaging (MEMRI), which uses manganese as a T1 contrast agent, has great potential for functional imaging of live neuronal tissue at single neuron scale. However, reaching high resolutions often requires long acquisition times which can lead to reduced image quality due to sample deterioration and hardware instability. Compressed Sensing (CS) techniques offer the opportunity to significantly reduce the imaging time. The purpose of this work is to test the feasibility of CS acquisitions based on Diffusion Limited Aggregation (DLA) sampling patterns for high resolution quantitative T1-weighted imaging...
May 9, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/28527992/enzymatic-and-acidic-degradation-of-high-molecular-weight-dextran-into-low-molecular-weight-and-its-characterizations-using-novel-diffusion-ordered-nmr-spectroscopy
#15
Samina Iqbal, Roberta Marchetti, Afsheen Aman, Alba Silipo, Shah Ali Ul Qader, Antonio Molinaro
Low molecular weight fractions were derived from native high molecular weight dextran produced by Leuconostoc mesenteroides KIBGE-IB26. Structural characterization of native and low molecular weight fractions obtained after acidic and enzymatic hydrolysis was done using FTIR and NMR spectroscopy. The molecular weight was estimated using Diffusion Ordered NMR spectroscopy. Native dextran (892kDa) is composed of α-(1→6) glycosidic linkage along with α-(1→3) branching. Major proportion of 528kDa dextran was obtained after prolong enzymatic hydrolysis however, an effective acidic treatment at pH-1...
May 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28526430/combination-of-integrated-dynamic-shimming-and-readout-segmented-echo-planar-imaging-for-diffusion-weighted-mri-of-the-head-and-neck-region-at-3tesla
#16
Sven S Walter, Wei Liu, Alto Stemmer, Petros Martirosian, Konstantin Nikolaou, Mike Notohamiprodjo, Sergios Gatidis
PURPOSE: To evaluate the performance of combined integrated slice-by-slice shimming and readout-segmented EPI (irsEPI) for diffusion-weighted MR imaging (DWI) of the neck at 3Tesla. METHODS: This study was approved by the local ethics committee. An anthropometric phantom of the head/neck region incorporating compartments with different diffusivities was constructed. In vivo measurements were performed in 10 healthy volunteers. DWI of the phantom and volunteers was performed on a 3Tesla MR scanner using single shot EPI (sEPI), a prototype single shot EPI with integrated slice-by-slice shimming (iEPI), readout segmented EPI (rsEPI) and a prototype readout segmented EPI with integrated shimming irsEPI...
May 16, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28525977/the-intracerebral-hemorrhage-acutely-decreasing-arterial-pressure-trial-ii-ich-adapt-ii-protocol
#17
Laura Gioia, Ana Klahr, Mahesh Kate, Brian Buck, Dariush Dowlatshahi, Thomas Jeerakathil, Derek Emery, Kenneth Butcher
BACKGROUND: Aggressively lowering blood pressure (BP) in acute intracerebral hemorrhage (ICH) may improve outcome. Although there is no evidence that BP reduction changes cerebral blood flow, retrospective magnetic resonance imaging (MRI) studies have demonstrated sub-acute ischemic lesions in ICH patients. The primary aim of this study is to assess ischemic lesion development in patients randomized to two different BP treatment strategies. We hypothesize aggressive BP reduction is not associated with ischemic injury after ICH...
May 19, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28524829/role-of-diffusion-weighted-and-contrast-enhanced-magnetic-resonance-imaging-in-differentiating-activity-of-ankylosing-spondylitis
#18
Ying-Hua Zhao, Yan-Yan Cao, Qun Zhang, Ying-Jie Mei, Ji-Jie Xiao, Shao-Yong Hu, Wei Li, Shao-Lin Li
BACKGROUND: Previous studies showed that combining apparent diffusion coefficient (ADC) value with the Spondyloarthritis Research Consortium of Canada (SPARCC) index value might provide a reliable evaluation of the activity of ankylosing spondylitis (AS), and that contrast-enhanced (CE) magnetic resonance imaging (MRI) is unnecessary. However, the results were based on confirming only a small random sample. This study aimed to assess the role of CE-MRI in differentiating the disease activity of AS by comparing ADC value with a large sample...
June 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28523963/brain-hypoxia-mapping-in-acute-stroke-back-to-back-t2-mr-versus-18-f-fluoromisonidazole-pet-in-rodents
#19
Ulf Jensen-Kondering, Roido Mavanaki, Sohail Ejaz, Stephen J Sawiak, T Adrian Carpenter, Tim D Fryer, Franklin I Aigbirhio, David J Williamson, Jean-Claude Baron
Background Mapping the hypoxic brain in acute ischemic stroke has considerable potential for both diagnosis and treatment monitoring. PET using (18)F-fluoro-misonidazole (FMISO) is the reference method; however, it lacks clinical accessibility and involves radiation exposure. MR-based T2' mapping may identify tissue hypoxia and holds clinical potential. However, its validation against FMISO imaging is lacking. Here we implemented back-to-back FMISO-PET and T2' MR in rodents subjected to acute middle cerebral artery occlusion...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28523355/mri-findings-in-men-on-active-surveillance-for-prostate-cancer-does-dutasteride-make-mri-visible-lesions-less-conspicuous-results-from-a-placebo-controlled-randomised-clinical-trial
#20
Francesco Giganti, Caroline M Moore, Nicola L Robertson, Neil McCartan, Charles Jameson, Simon R J Bott, Mathias Winkler, Giulio Gambarota, Brandon Whitcher, Ramiro Castro, Mark Emberton, Clare Allen, Alex Kirkham
OBJECTIVES: To investigate changes in the Apparent Diffusion Coefficient (ADC) using diffusion-weighted imaging (DWI) in men on active surveillance for prostate cancer taking dutasteride 0.5 mg or placebo. METHODS: We analysed 37 men, randomised to 6 months of daily dutasteride (n = 18) or placebo (n = 19), undergoing 3T multi-parametric Magnetic Resonance Imaging (mpMRI) scans at baseline and 6 months. Images were reviewed blind to treatment allocation and clinical information...
May 18, 2017: European Radiology
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