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Diffusion weighted

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https://www.readbyqxmd.com/read/27909774/evaluation-of-upper-abdominal-organs-with-dwi-in-patients-with-familial-mediterranean-fever
#1
Eda Albayrak, Safak Sahin
PURPOSE: To investigate the diagnostic efficiency of diffusion-weighted magnetic resonance imaging (DWI) for the evaluation of functional changes that can occur in upper abdominal organs in patients with familial Mediterranean fever (FMF). METHODS: The study included 50 controls, 45 patients with FMF, and 14 patients with FMF who had accompanying proteinuria. Measurement of apparent diffusion coefficient (ADC) was performed using DWI sections obtained from liver, spleen, kidney, and pancreas parenchyma with 1...
December 2, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27909201/infarct-pattern-and-collateral-status-in-adult-moyamoya-disease-a-multimodal-magnetic-resonance-imaging-study
#2
Dong Yeop Kim, Jeong Pyo Son, Je Young Yeon, Gyeong-Moon Kim, Jong-Soo Kim, Seung-Chyul Hong, Oh Young Bang
BACKGROUND AND PURPOSE: Moyamoya disease (MMD) is a unique cerebrovascular disease characterized by the progressive stenosis of large intracranial arteries and a hazy network of basal collaterals, called moyamoya vessels. Although hemodynamic studies have been applied in MMD patients, the mechanisms of stroke in MMD are still unclear. The present study evaluated the infarct pattern and collateral status using multimodal magnetic resonance imaging in MMD patients. METHODS: Adult MMD patients with acute ischemic stroke were prospectively recruited, and infarct pattern on diffusion-weighted imaging was evaluated...
December 1, 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27908444/clinical-application-of-apparent-diffusion-coefficient-mapping-in-voxel-based-morphometry-in-the-diagnosis-of-alzheimer-s-disease
#3
H Takahashi, K Ishii, N Kashiwagi, Y Watanabe, H Tanaka, T Murakami, N Tomiyama
AIM: To evaluate the performance of apparent diffusion coefficient (ADC) mapping compared with voxel-based morphometry and to demonstrate the clinical usefulness of ADC mapping in the diagnosis of Alzheimer's disease (AD). MATERIALS AND METHODS: The study population comprised 31 patients with AD (group A) and 24 patients without dementia (group B) who underwent three-dimensional (3D) T1-weighted imaging (WI) and two-dimensional (2D) echo-planar diffusion-weighted imaging (DWI) at 3 T...
November 28, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27908306/comparing-diffusion-weighted-imaging-with-clinical-and-blood-parameters-and-with-short-tau-inversion-recovery-sequence-in-detecting-spinal-and-sacroiliac-joint-inflammation-in-axial-spondyloarthritis
#4
Ho Yin Chung, Xiaopei Xu, Vince Wing Hang Lau, Grace Ho, Ka Lai Lee, Philip Hei Li, Helen Hoi Lun Tsang, Suet Kei Kwok, Chak Sing Lau, Chun Sing Wong
OBJECTIVES: To investigate the usefulness of diffusion weighted imaging (DWI) by comparing with clinical features, blood parameters and traditional short tau inversion recovery (STIR) sequence in detecting spinal and sacroiliac (SI) joint inflammation in axial spondyloarthritis (axSpA) patients. METHODS: One hundred and ten axSpA patients were recruited. Clinical, radiological and blood parameters were recorded. DWI and STIR MRI were performed simultaneously and results were scored according to the Spondyloarthritis Research Consortium of Canada (SPARCC) for comparison...
November 13, 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27908189/thermoacoustic-imaging-of-rabbit-knee-joints
#5
Zihui Chi, Yuan Zhao, Lin Huang, Zhu Zheng, Huabei Jiang
PURPOSE: Knee joint is one of the largest and most complex joints of the body. Knee joint diseases are common, and current clinical imaging technologies such as x-ray computed tomography, magnetic resonance imaging, and ultrasound imaging have limitations in the diagnosis of knee joint diseases. Emerging imaging technologies such as diffuse optical tomography and photoacoustic imaging (PAI) have been applied to the detection of osteoarthritis (OA). However, they are limited to small joints such as the finger and difficult to be used for large joints such as the knee...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27906917/efficacy-and-safety-of-tc-325-hemospraytm-for-non-variceal-upper-gastrointestinal-bleeding-at-middlemore-hospital-the-early-new-zealand-experience
#6
Hannah Giles, Dinesh Lal, Stephen Gerred, Paul Casey, Alasdair Patrick, Derek Luo, Ravinder Ogra
AIMS: A case series to review early experiences with HemosprayTM for a variety of non-variceal upper gastrointestinal bleeding (UGIB) at Middlemore Hospital. METHODS: HemosprayTM was administered therapeutically as first line or rescue at the discretion of the endoscopist. All cases of UGIB requiring HemosprayTM at Middlemore Hospital were identified to the investigator who undertook analysis of electronic and hard copy notes. RESULTS: Between October 2013 and July 2016, 36 patients were treated endoscopically with HemosprayTM...
December 2, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27906083/neonatal-diffusion-tensor-brain-imaging-predicts-later-motor-outcome-in-preterm-neonates-with-white-matter-abnormalities
#7
Do-Yeon Kim, Hyun-Kyung Park, Nam-Su Kim, Se-Jin Hwang, Hyun Ju Lee
BACKGROUND: White matter (WM) abnormalities associated with prematurity are one of the most important causes of neurological disability that involves spastic motor deficits in preterm newborns. This study aimed to evaluate regional microstructural changes in diffusion tensor imaging (DTI) associated with WM abnormalities. METHODS: We prospectively studied extremely low birth weight (ELBW; <1000 g) preterm infants who were admitted to the Neonatal Intensive Care Unit of Hanyang University Hospital between February 2011 and February 2014...
December 1, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27905899/a-case-of-extragastrointestinal-stromal-tumor-complicated-by-severe-hypoglycemia-a-unique-presentation-of-a-rare-tumor
#8
Zeb Saeed, Solaema Taleb, Carmella Evans-Molina
BACKGROUND: Non-Islet Cell Tumor Hypoglycemia (NICTH) is a rare paraneoplastic cause of hypoglycemia arising from excess tumor production of insulin-like growth factor. The objective of this report is to describe an unusual case of Extragastrointestinal Stromal Tumor (EGIST) associated NICTH. CASE PRESENTATION: A 64 year-old African female was brought to the emergency room with a 1-month history of recurrent syncope, weight loss, and abdominal bloating. Serum blood glucose was discovered to 39 mg/dL, when insulin, proinsulin, and C-peptide were suppressed...
December 1, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27904923/can-diffusion-weighted-magnetic-resonance-imaging-of-clear-cell-renal-carcinoma-predict-low-from-high-nuclear-grade-tumors
#9
Carolina Parada Villavicencio, Robert J Mc Carthy, Frank H Miller
OBJECTIVE: To assess the diagnostic performance of the apparent diffusion coefficient (ADC) in predicting the Fuhrman nuclear grading of clear cell renal cell carcinomas (ccRCC). MATERIALS AND METHODS: A total of 129 patients who underwent partial and radical nephrectomies with pathology-proven ccRCC were retrospectively evaluated. Histopathological characteristics and nuclear grades were analyzed. In addition, conventional magnetic resonance imaging (MRI) features were assessed in consensus by two radiologists to discriminate nuclear grading...
December 1, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27903921/a-two-pool-model-to-describe-the-ivim-cerebral-perfusion
#10
Gabrielle Fournet, Jing-Rebecca Li, Alex M Cerjanic, Bradley P Sutton, Luisa Ciobanu, Denis Le Bihan
IntraVoxel Incoherent Motion (IVIM) is a magnetic resonance imaging (MRI) technique capable of measuring perfusion-related parameters. In this manuscript, we show that the mono-exponential model commonly used to process IVIM data might be challenged, especially at short diffusion times. Eleven rat datasets were acquired at 7T using a diffusion-weighted pulsed gradient spin echo sequence with b-values ranging from 7 to 2500 s/mm(2) at three diffusion times. The IVIM signals, obtained by removing the diffusion component from the raw MR signal, were fitted to the standard mono-exponential model, a bi-exponential model and the Kennan model...
November 30, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27903456/millifluidic-synthesis-of-amorphous-drug-polysaccharide-nanoparticle-complex-with-tunable-size-intended-for-supersaturating-drug-delivery-applications
#11
The-Thien Tran, Minh-Hiep Nguyen, Yong Zen Tan, Jia Wei Chew, Saif A Khan, Kunn Hadinoto
The conventional bulk mixing method to prepare amorphous drug-polysaccharide nanoparticle complex (or drug nanoplex in short) has a major drawback in the lack of size control for the nanoplex produced, hence limiting its potential applications as a supersaturating drug delivery system for bioavailability enhancement of poorly soluble drugs. For this reason, we developed a continuous millifluidic synthesis platform of the drug nanoplex exhibiting high size tunability using curcumin (CUR) and chitosan (CHI) as the models for drug and polysaccharides, respectively...
November 27, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/27903187/stereotactic-diffusion-tensor-imaging-tractography-for-gamma-knife-radiosurgery
#12
Cormac G Gavin, H Ian Sabin
OBJECTIVE The integration of modern neuroimaging into treatment planning has increased the therapeutic potential and safety of stereotactic radiosurgery. The authors report their method of integrating stereotactic diffusion tensor imaging (DTI) tractography into conventional treatment planning for Gamma Knife radiosurgery (GKRS). The aim of this study was to demonstrate the feasibility of this technique and to address some of the technical limitations of previously reported techniques. METHODS Twenty patients who underwent GKRS composed the study cohort...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27903157/obesity-and-other-cancers
#13
Lin Yang, Bettina F Drake, Graham A Colditz
Purpose Evidence on overweight, obesity, and an increased risk of cancer continues to accumulate and was updated in the 2016 handbook on weight control from the International Agency for Research on Cancer (IARC). The underlying primary data, together with dose-response meta-analysis and, finally, pooled analysis of individual participant data, add insight into the relation between obesity and cancer risk and prognosis. We summarize the evidence for mortality from prostate cancer, hematologic malignancies, and kidney cancer...
December 10, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27902984/evaluation-of-club-cell-10-kda-protein-cc10-levels-in-full-term-infants
#14
Nasim Gorji, Aprile L Pilon, Melissa E Winn, Morgan Newsome, Jonathan M Davis
BACKGROUND: The club cell 10-kDa protein (CC10) is a homeostatic protein that is produced in the lung, diffuses into the blood, and is then excreted into the urine and stool. CC10 is known to have anti-inflammatory properties and to have lower endogenous production in preterm infants. OBJECTIVES: As recombinant human CC10 (rhCC10) is being studied in preterm infants to reduce lung injury, understanding CC10 levels in term infants with normal lungs is needed to establish appropriate target dosing ranges...
December 1, 2016: Neonatology
https://www.readbyqxmd.com/read/27902599/could-adc-values-be-a-promising-diagnostic-criterion-for-differentiating-malignant-and-benign-hepatic-lesions-in-asian-populations-a-meta-analysis
#15
Jing Peng, Jing-Jin Li, Jiang Li, He-Wen Li, Guo-Ping Xu, Rong-Rong Jia, Xue-Ning Zhang, Yang Zhao
BACKGROUND: Liver cancer exhibits geographic and ethnic differences in its prevalence and biology, which implies that it is impractical to develop universal guidelines for all patients. Thus, a meta-analysis was conducted to identify the accuracy of apparent diffusion coefficients (ADCs) for discriminating malignant from benign liver lesions in Asians. METHODS: Eligible studies published in PubMed, Ovid, and Embase/Medline were updated onto October 2014. STATA 12...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27899884/the-inverse-relationship-between-the-microstructural-variability-of-amygdala-prefrontal-pathways-and-trait-anxiety-is-moderated-by-sex
#16
M Justin Kim, Annemarie C Brown, Alison M Mattek, Samantha J Chavez, James M Taylor, Amy L Palmer, Yu-Chien Wu, Paul J Whalen
Anxiety impacts the quality of everyday life and may facilitate the development of affective disorders, possibly through concurrent alterations in neural circuitry. Findings from multimodal neuroimaging studies suggest that trait-anxious individuals may have a reduced capacity for efficient communication between the amygdala and the ventral prefrontal cortex (vPFC). A diffusion-weighted imaging protocol with 61 directions was used to identify lateral and medial amygdala-vPFC white matter pathways. The structural integrity of both pathways was inversely correlated with self-reported levels of trait anxiety...
2016: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/27899333/abnormalities-of-brain-neural-circuits-related-to-obesity-a-diffusion-tensor-imaging-study
#17
Ioannis Papageorgiou, Loukas G Astrakas, Vassileios Xydis, George Alexiou, Panagiotis Bargiotas, Loukia Tzarouchi, Anastasia K Zikou, Dimitrios N Kiortsis, Maria I Argyropoulou
PURPOSE: Increased Body-Mass-Index (BMI) has been associated with brain atrophy in both gray and white matter structures. However, little is known concerning the integrity of white matter tracts in obesity. The purpose of the study was to evaluate the pattern of changes in white matter microstructure in human adiposity. MATERIAL AND METHODS: The study included 268 participants (52 obese, 96 overweight and 120 normal-weight) that were retrospectively evaluated by Diffusion Tensor Imaging...
November 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27898647/diffusion-weighted-mri-and-18f-fdg-pet-ct-imaging-competition-or-synergy-as-diagnostic-methods-to-manage-sarcoma-of-the-uterus-a-systematic-review-of-the-literature
#18
Julien Dubreuil, Jeremie Tordo, Domenico Rubello, Francesco Giammarile, Andrea Skanjeti
AIM: To evaluate the diagnostic performance of fluorine-18-fluorodeoxyglucose PET/computed tomography (F-FDG-PET/CT) and MRI with diffusion-weighted images (DWI) in uterine sarcomas (US). PATIENTS AND METHODS: A systematic review was performed on Medline, ISI web of knowledge, and Scopus databases for studies reporting the diagnostic performance of F-FDG-PET/CT and DWI-MRI in US published up to 15 February 2016. Exclusion criteria were articles with fewer than five cases of US, without DWI-MRI, and previous series of patients from the same researcher team...
January 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/27898201/diffusion-weighted-imaging-of-the-abdomen-impact-of-b-values-on-texture-analysis-features
#19
Anton S Becker, Matthias W Wagner, Moritz C Wurnig, Andreas Boss
The purpose of this work was to systematically assess the impact of the b-value on texture analysis in MR diffusion-weighted imaging (DWI) of the abdomen. In eight healthy male volunteers, echo-planar DWI sequences at 16 b-values ranging between 0 and 1000 s/mm(2) were acquired at 3 T. Three different apparent diffusion coefficient (ADC) maps were computed (0, 750/100, 390, 750 s/mm(2) /all b-values). Texture analysis of rectangular regions of interest in the liver, kidney, spleen, pancreas, paraspinal muscle and subcutaneous fat was performed on DW images and the ADC maps, applying 19 features computed from the histogram, grey-level co-occurrence matrix (GLCM) and grey-level run-length matrix (GLRLM)...
November 29, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27896893/an-acute-disseminated-encephalomyelitis-like-illness-in-the-elderly-neuroimaging-and-neuropathology-findings
#20
Ulrike W Kaunzner, Elliott Salamon, Elena Pentsova, Marc Rosenblum, Sasan Karimi, Nancy Nealon, Ehud Lavi, Dara G Jamieson
INTRODUCTION: Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating disease of the central nervous system (CNS) that classically occurs in children and adolescents. It characteristically presents with acute inflammation, resulting in demyelination, often following an infectious disease. ADEM has been described in adult patients, but the incidence in the adult and especially elderly population is low. CASES: We describe five older adults (age 57 to 85) who presented with acute neurological symptoms...
November 29, 2016: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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