Patricia Alejandra Garrido Ruiz, María González-Tablas, Alejandro Pasco Peña, María Victoria Zelaya Huerta, Javier Ortiz, Álvaro Otero, Luis Antonio Corchete, María Dolores Ludeña, María Cristina Caballero Martínez, Alicia Córdoba Iturriagagoitia, Inmaculada Catalina Fernández, Joaquín González-Carreró Fojón, Aurelio Hernández Laín, Alberto Orfao, María Dolores Tabernero
Rhabdoid meningiomas (RM) shows heterogeneous histological findings, and a wide variety of chromosomal copy number alterations (CNA) are associated with an unpredictable course of the disease. In this study, we analyzed a series of 305 RM samples from patients previously reported in the literature and 33 samples from 23 patients studied in our laboratory. Monosomy 22-involving the minimal but most common recurrent region loss of the 22q11.23 chromosomal region was the most observed chromosomal alteration, followed by losses of chromosomes 14, 1, 6, and 19, polysomies of chromosomes 17, 1q, and 20, and gains of 13q14...
January 6, 2023: International Journal of Molecular Sciences