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Neurocognitive testing

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https://www.readbyqxmd.com/read/27905859/baseline-neurocognitive-performance-and-clearance-for-athletes-to-return-to-contact
#1
Breton M Asken, James R Clugston, Aliyah R Snyder, Russell M Bauer
CONTEXT:  Computerized neurocognitive assessments are commonly used to manage sport-related concussion. Variations in baseline performance may influence neurocognitive performance after injury as well as the amount of time needed for an athlete to be cleared for return to sport participation. OBJECTIVE:  To investigate the relationship between mean baseline Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) scores and postconcussion reliable decline as well as the association between postconcussion cognitive decline and days missed after injury...
December 1, 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27904515/interaction-between-c-reactive-protein-and-cognitive-functions-according-to-apoe-gene-polymorphism-in-post-menopausal-women
#2
Iwona Bojar, Mariusz Gujski, Jarosław Pinkas, Dorota Raczkiewicz, Alfred Owoc, Ewa Humeniuk
INTRODUCTION: A potential factor increasing the risk of the development of cognitive impairment with age is apolipoprotein E (APOE) ε4 carrier status. A subsequent factor which may increase the risk of development of cognitive impairment at an older age is the concentration of C-reactive protein (CRP). The objective of the study was to examine the relationship between cognitive functions and the concentration of CRP in post-menopausal women who were carriers of particular apolipoprotein E gene (APOE) polymorphisms...
December 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27903328/cognitive-and-behavioral-functioning-in-childhood-acquired-demyelinating-syndromes
#3
Christine Till, Austin Noguera, Leonard H Verhey, Julia O'Mahony, E Ann Yeh, Jean K Mah, Katia J Sinopoli, Brian L Brooks, Berengere Aubert-Broche, D Louis Collins, Sridar Narayanan, Douglas L Arnold, Brenda L Banwell
OBJECTIVES: The aim of this study was to describe cognitive, academic, and psychosocial outcomes after an incident demyelinating event (acquired demyelinating syndromes, ADS) in childhood and to investigate the contribution of brain lesions and confirmed MS diagnosis on outcome. METHODS: Thirty-six patients with ADS (mean age=12.2 years, SD=2.7, range: 7-16 years) underwent brain MRI scans at presentation and at 6-months follow-up. T2-weighted lesions on MRI were assessed using a binary classification...
November 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27901245/transcranial-direct-current-stimulation-for-treatment-resistant-obsessive-compulsive-disorder-report-on-two-cases-and-proposal-for-a-randomized-sham-controlled-trial
#4
Renata de Melo Felipe da Silva, André Russowsky Brunoni, Eurípedes Constantino Miguel, Roseli Gedanke Shavitt
CONTEXT AND OBJECTIVE: Neuromodulation techniques for treating obsessive-compulsive disorder (OCD) have expanded through greater understanding of the brain circuits involved in this disorder. Transcranial direct current stimulation (tDCS), a non-invasive technique, has been studied as an alternative for treatment-resistant OCD. We describe the design of a clinical trial using tDCS for OCD and report on the outcomes from two patients with primary OCD who were resistant to cognitive-behavioral therapy and to selective serotonin reuptake inhibitors, and who received tDCS in an open manner during the training phase for the study procedures...
September 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/27900145/the-sensitivity-and-specificity-of-clinical-measures-of-sport-concussion-three-tests-are-better-than-one
#5
Jacob E Resch, Cathleen N Brown, Julianne Schmidt, Stephen N Macciocchi, Damond Blueitt, C Munro Cullum, Michael S Ferrara
CONTEXT: A battery of clinical measures of neurocognition, balance and symptoms has been recommended for the management of sport concussion (SC) but is based on variable evidence. OBJECTIVE: To examine the sensitivity and specificity of a battery of tests to assess SC in college athletes. DESIGN: Cross-sectional. SETTING: Research laboratory. PATIENTS OR OTHER PARTICIPANTS: Division 1 athletes diagnosed with a SC (n=40) who were 20...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899165/cognitive-dysfunction-in-body-dysmorphic-disorder-new-implications-for-nosological-systems-and-neurobiological-models
#6
Kiri Jefferies-Sewell, Samuel R Chamberlain, Naomi A Fineberg, Keith R Laws
: Introduction Body dysmorphic disorder (BDD) is a debilitating disorder, characterized by obsessions and compulsions relating specifically to perceived appearance, and which has been newly classified within the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) Obsessive-Compulsive and Related Disorders grouping. Until now, little research has been conducted into the cognitive profile of this disorder. METHODS: Participants with BDD (n=12) and participants without BDD (n=16) were tested using a computerized neurocognitive battery investigating attentional set-shifting (Intra/Extra Dimensional Set Shift Task), decision-making (Cambridge Gamble Task), motor response-inhibition (Stop-Signal Reaction Time Task), and affective processing (Affective Go-No Go Task)...
November 30, 2016: CNS Spectrums
https://www.readbyqxmd.com/read/27896574/cognitive-function-in-early-hiv-infection
#7
Aanchal Prakash, Jue Hou, Lei Liu, Yi Gao, Casey Kettering, Ann B Ragin
This study aimed to examine cognitive function in acute/early HIV infection over the subsequent 2 years. Fifty-six HIV+ subjects and 21 seronegative participants of the Chicago Early HIV Infection Study were evaluated using a comprehensive neuropsychological assessment at study enrollment and at 2-year follow-up. Cognitive performance measures were compared in the groups using t tests and mixed-effect models. Patterns of relationship with clinical measures were determined between cognitive function and clinical status markers using Spearman's correlations...
November 28, 2016: Journal of Neurovirology
https://www.readbyqxmd.com/read/27894373/cognitive-effects-of-adjunctive-n-acetyl-cysteine-in-psychosis
#8
M Rapado-Castro, S Dodd, A I Bush, G S Malhi, D R Skvarc, Z X On, M Berk, O M Dean
BACKGROUND: Cognitive deficits are predictors of functional outcome in patients with psychosis. While conventional antipsychotics are relatively effective on positive symptoms, their impact on negative and cognitive symptoms is limited. Recent studies have established a link between oxidative stress and neurocognitive deficits in psychosis. N-acetylcysteine (NAC), a glutathione precursor with glutamatergic properties, has shown efficacy on negative symptoms and functioning in patients with schizophrenia and bipolar disorder, respectively...
November 29, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27892704/the-effects-of-a-16-week-aerobic-exercise-programme-on-cognitive-function-in-people-living-with-hiv
#9
Adam McDermott, Lilia Zaporojan, Patricia McNamara, Colin P Doherty, Janice Redmond, Cuisle Forde, John Gormley, Mikel Egaña, Colm Bergin
High levels of cardiovascular fitness and physical activity are associated with higher levels of cognitive function in people with HIV, thus, they may reduce the risk of developing HIV-associated neurocognitive disorder (HAND). This study aimed to investigate the effects of a 16-week aerobic exercise intervention on cognitive function in people with HIV. Eleven participants living with HIV were recruited into the study. Participants were randomised into either an exercise group (n = 5), that completed a 16-week aerobic exercise programme training, 3 times per week (2 supervised sessions and one unsupervised session) or a control group (n = 6) that received no intervention...
November 28, 2016: AIDS Care
https://www.readbyqxmd.com/read/27890777/psychological-wellbeing-in-survivors-of-cardiac-arrest-and-its-relationship-to-neurocognitive-function
#10
Siân E Davies, Megan Rhys, Sarah E Voss, Rosemary Greenwood, Matthew Thomas, Jonathan R Benger
OBJECTIVE: To characterise psychological wellbeing in survivors of out-of-hospital cardiac arrest (OHCA), and examine its relationship to cognitive function. PATIENTS: Forty-one highly functioning cardiac arrest survivors were drawn from the follow-up cohort of a randomised controlled trial of initial airway management in OHCA (ISRCTN:18528625). DESIGN: Psychological wellbeing was assessed with a self-report questionnaire (the Depression Anxiety and Stress Scale; DASS) and cognitive function was examined using the Delayed Matching to Samples (DMS) test from the Cambridge Neuropsychological Test Automated Battery (CANTAB)...
November 24, 2016: Resuscitation
https://www.readbyqxmd.com/read/27889592/marijuana-effects-on-changes-in-brain-structure-and-cognitive-function-among-hiv-and-hiv-adults
#11
April D Thames, Taylor P Kuhn, Timothy J Williamson, Jacob D Jones, Zanjbeel Mahmood, Andrea Hammond
BACKGROUND: The current study examined the independent and interactive effects of HIV and marijuana (MJ) use on brain structure and cognitive function among a sample of HIV-positive (HIV+) and HIV-negative (HIV-) individuals. METHODS: Participants (HIV+, n=48; HIV-, n=29) individuals underwent cognitive testing, questionnaires about substance use, and brain MRI. The HIV+ group was clinically stable based upon current plasma CD4 count, 50% had undetectable viral load (i...
November 14, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27888683/lifetime-antipsychotic-medication-and-cognitive-performance-in-schizophrenia-at-age-43-years-in-a-general-population-birth-cohort
#12
Anja P Husa, Jani Moilanen, Graham K Murray, Riikka Marttila, Marianne Haapea, Irina Rannikko, Jennifer H Barnett, Peter B Jones, Matti Isohanni, Anne M Remes, Hannu Koponen, Jouko Miettunen, Erika Jääskeläinen
This naturalistic study analysed the association between cumulative lifetime antipsychotic dose and cognition in schizophrenia after an average of 16.5 years of illness. Sixty participants with schizophrenia and 191 controls from the Northern Finland Birth Cohort 1966 were assessed at age 43 years with a neurocognitive test battery. Cumulative lifetime antipsychotic dose-years were collected from medical records and interviews. The association between antipsychotic dose-years and a cognitive composite score based on principal component analysis was analysed using linear regression...
November 12, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27884563/combined-associations-of-sedentary-behavior-and-cardiorespiratory-fitness-on-cognitive-function-among-older-adults
#13
Meghan K Edwards, Paul D Loprinzi
BACKGROUND: Sedentary behavior, cardiorespiratory fitness, cognition and age are interrelated and associated with cardiovascular function. No study, however, has specifically evaluated the independent and combined associations of cardiorespiratory fitness and sedentary behavior on cognition, which was this study's purpose. METHODS: Data from the 1999-2002 NHANES were used (N=2451; 60-85yrs). Sedentary behavior was assessed via self-report; cardiorespiratory fitness was assessed from a medical-related algorithm; and cognition function was assessed from the Digit Symbol Substitution Test (DSST)...
November 18, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27884217/from-neurocognition-to-community-participation-in-serious-mental-illness-the-intermediary-role-of-dysfunctional-attitudes-and-motivation
#14
E C Thomas, L Luther, L Zullo, A T Beck, P M Grant
BACKGROUND: Evidence for a relationship between neurocognition and functional outcome in important areas of community living is robust in serious mental illness research. Dysfunctional attitudes (defeatist performance beliefs and asocial beliefs) have been identified as intervening variables in this causal chain. This study seeks to expand upon previous research by longitudinally testing the link between neurocognition and community participation (i.e. time in community-based activity) through dysfunctional attitudes and motivation...
November 25, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27877044/increased-mir-132-level-is-associated-with-visual-memory-dysfunction-in-patients-with-depression
#15
Ye Liu, Xiao Yang, Liansheng Zhao, Jian Zhang, Tao Li, Xiaohong Ma
BACKGROUND: Impaired visual memory seems to be a core feature of depression, while increased microRNA-132 (miR-132) levels have been widely reported in depression patients. The authors aimed to explore the relationship between miR-132 changes and visual memory deficits in unmedicated patients with major depressive disorder (MDD). PATIENTS AND METHODS: A total of 62 medication-free MDD patients and 73 matched healthy controls (HCs) were tested for miR-132 expression level in peripheral blood using quantitative real-time polymerase chain reaction...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27875931/early-numeracy-skills-in-preschool-aged-children-a-review-of-neurocognitive-findings-and-implications-for-assessment-and-intervention
#16
Kimberly P Raghubar, Marcia A Barnes
OBJECTIVES: The goals are to (1) provide a review of the typical and atypical development of early numeracy; (2) present what is known about the neurocognitive underpinnings of early numeracy; and (3) discuss the implications for early assessment and intervention. METHOD: Studies on the development of typical and atypical early numeracy are reviewed with a particular focus on longitudinal findings including those from our work on spina bifida myelomeningocele. Implications of this research for assessment are presented...
November 23, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27871574/cerebral-oxygenation-in-the-beach-chair-position-for-shoulder-surgery-in-regional-anesthesia-impact-on-cerebral-blood-flow-and-neurobehavioral-outcome
#17
José A Aguirre, Olivia Märzendorfer, Muriel Brada, Andrea Saporito, Alain Borgeat, Philipp Bühler
STUDY OBJECTIVE: Beach chair position is considered a potential risk factor for central neurological events particularly if combined with low blood pressure. The aim of this study was to assess the impact of regional anesthesia on cerebral blood flow and neurobehavioral outcome. DESIGN: This is a prospective, assessor-blinded observational study evaluating patients in the beach chair position undergoing shoulder surgery under regional anesthesia. SETTING: University hospital operating room...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27871032/level-of-serum-thioredoxin-and-correlation-with-neurocognitive-functions-in-patients-with-schizophrenia-using-clozapine-and-other-atypical-antipsychotics
#18
Alper Bas, Gozde Gultekin, Said Incir, Tuba Ocek Bas, Murat Emul, Alaatin Duran
Thioredoxin is a serum antioxidant that has been investigated in the etiology of schizophrenia. The aim of this study is investigating the relationship between serum thioredoxin levels and cognitive functions in acute psychotic episode and remission state patients with schizophrenia; and examining whether there were differences between patients using clozapine and other atypical antipsychotics; including risperidone, olanzapine and amisulpride. This research was performed in schizophrenia patients hospitalized with acute psychotic episode (n=57), reevaluated patients after the initiation of treatment (mean 16 weeks) (n=46), and healthy controls (n=41)...
November 15, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27869058/relationship-of-amotivation-to-neurocognition-self-efficacy-and-functioning-in-first-episode-psychosis-a-structural-equation-modeling-approach
#19
W C Chang, V W Y Kwong, C L M Hui, S K W Chan, E H M Lee, E Y H Chen
BACKGROUND: Better understanding of the complex interplay among key determinants of functional outcome is crucial to promoting recovery in psychotic disorders. However, this is understudied in the early course of illness. We aimed to examine the relationships among negative symptoms, neurocognition, general self-efficacy and global functioning in first-episode psychosis (FEP) patients using structural equation modeling (SEM). METHOD: Three hundred and twenty-one Chinese patients aged 26-55 years presenting with FEP to an early intervention program in Hong Kong were recruited...
November 21, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27868225/first-language-attrition-induces-changes-in-online-morphosyntactic-processing-and-re-analysis-an-erp-study-of-number-agreement-in-complex-italian-sentences
#20
Kristina Kasparian, Francesco Vespignani, Karsten Steinhauer
First language (L1) attrition in adulthood offers new insight on neuroplasticity and the role of language experience in shaping neurocognitive responses to language. Attriters are multilinguals for whom advancing L2 proficiency comes at the cost of the L1, as they experience a shift in exposure and dominance (e.g., due to immigration). To date, the neurocognitive mechanisms underlying L1 attrition are largely unexplored. Using event-related potentials (ERPs), we examined L1-Italian grammatical processing in 24 attriters and 30 Italian native-controls...
November 7, 2016: Cognitive Science
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