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https://www.readbyqxmd.com/read/29684443/modified-porcine-surfactant-enriched-by-recombinant-human-superoxide-dismutase-for-experimental-meconium-aspiration-syndrome
#1
Jana Kopincova, Pavol Mikolka, Maros Kolomaznik, Petra Kosutova, Andrea Calkovska, Daniela Mokra
AIMS: Combination of exogenous surfactant with antioxidant enzyme recombinant human superoxide dismutase (rhSOD) was tested in the treatment of experimental meconium aspiration syndrome as oxidative processes play key role in its pathogenesis. MATERIAL AND METHODS: Young New Zealand rabbits were instilled by saline (Sal group) or by meconium suspension (Mec group). Some of meconium-instilled animals were treated by surfactant alone (Surf group) or surfactant in combination with rhSOD (Surf + SOD group) and oxygen-ventilated for 5 h...
April 20, 2018: Life Sciences
https://www.readbyqxmd.com/read/29684029/dispersion-and-oviposition-of-aedes-albopictus-in-a-brazilian-slum-initial-evidence-of-asian-tiger-mosquito-domiciliation-in-urban-environments
#2
Tania Ayllón, Daniel Cardoso Portela Câmara, Fernanda Cristina Morone, Larissa da Silva Gonçalves, Fábio Saito Monteiro de Barros, Patrícia Brasil, Marilia Sá Carvalho, Nildimar Alves Honório
Aedes albopictus, originally considered as a secondary vector for arbovirus transmission, especially in areas where this species co-exist with Aedes aegypti, has been described in most regions of the world. Dispersion and domiciliation of Ae. albopictus in a complex of densely urbanized slums in Rio de Janeiro, Southeastern Brazil, was evidenced. In this study, we tested the hypotheses that 1) Ae. albopictus distribution in urban slums is negatively related to distance from vegetation, and 2) these vectors have taken on a domestic life style with a portion of the population feeding, ovipositing, and resting indoors...
2018: PloS One
https://www.readbyqxmd.com/read/29679838/medico-legal-investigation-in-an-explicable-case-of-congenital-central-hypoventilation-syndrome-due-to-a-rare-variant-of-the-phox2b-gene
#3
Francesco Ventura, Rosario Barranco, Tiziana Bachetti, Paolo Nozza, Ezio Fulcheri, Antonella Palmieri, Isabella Ceccherini
The heterozygous PHOX2B gene mutation is related to congenital central hypoventilation syndrome (CCHS). It is characterized by defective autonomous nervous system development leading to inadequate breathing response to hypoxia and hypercapnia, leading to hypoventilation especially during non-REM sleep, but also during waking in the more severe cases. Herein we report a case of sudden death in a 28-day-old child. The mother reported the infant was found lying on her own bed in the prone position. The infant was wearing a romper and lying in her crib without any blanket or other objects...
April 17, 2018: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29666557/the-impact-of-delayed-sample-handling-and-type-of-anticoagulant-on-the-interpretation-of-dysplastic-signs-detected-by-flow-cytometry
#4
Bettina Kárai, Zsófia Miltényi, Lajos Gergely, Marianna Száraz-Széles, János Kappelmayer, Zsuzsanna Hevessy
Introduction: A growing body of evidence supports the usefulness of dysplastic signs detected by flow cytometry in the diagnosis of myelodysplastic syndromes (MDS). Our aim was to assess the impact of pre-analytical variables (delayed sample handling, type of anticoagulant, and different clones of antibody) in the interpretation of flow cytometric results. Material and methods: Bone marrow samples were labelled and analysed immediately after aspiration and on two consecutive days...
June 15, 2018: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/29663723/intraocular-metastasis-of-medullary-thyroid-carcinoma-investigated-by-transscleral-fine-needle-aspiration-a-case-report-and-review-of-the-literature
#5
Małgorzata Gajdzis, Nathalie Cassoux, Maria Lesnik, Caroline Hoffmann, Nathalie Badois, Paweł Gajdzis, Jerzy Klijanienko
Medullary thyroid carcinoma occurs in a sporadic setting and may also be inherited in an autosomal dominant fashion, which is related with germline mutations of the RET gene. Metastases are often present at the time of a diagnosis-most frequently within the cervical lymph nodes, followed by the liver, lungs, and bones. Intraocular metastases are extremely rare. We present a case of choroidal metastasis as a first presentation of disease progression in a patient with Multiple Endocrine Neoplasia type 2A syndrome (MEN2A) who had undergone thyroidectomy 33 years earlier for medullary thyroid carcinoma...
April 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29659363/-late-diagnosis-of-whim-sydrome
#6
María V Paolini, Silvia Danielian, Emma Prieto, María Fernanda Tami, Matías M Oleastro, Diego S Fernández Romero
WHIM syndrome is a primary autosomal dominant immuno deficiency due to CXCR4 mutations characterized by mucocutaneous warts, hypogammaglobulinemia, recurrent bacterial infections and myelokathesis. Treatment consists in prophylactic antibiotics, immunoglobulin replacement and granulocyte or granulocyte/monocyte colony stimulating factors. We present the case of a 21 year old woman who showed leukopenia at 10 months of age and one year later multiple infections with hypogammaglobulinemia requiring intravenous immunoglobulin...
2018: Medicina
https://www.readbyqxmd.com/read/29629694/effect-of-gastric-lavage-on-meconium-aspiration-syndrome-and-feed-intolerance-in-vigorous-infants-born-with-meconium-stained-amniotic-fluid-a-randomized-control-trial
#7
Shrishail Gidaganti, M M A Faridi, Manish Narang, Prerna Batra
OBJECTIVE: To compare the incidence of meconium aspiration syndrome and feed intolerance in infants born through meconium stained amniotic fluid with or without gastric lavage performed at birth. SETTING: Neonatal unit of a teaching hospital in New Delhi, India. DESIGN: Parallel group unmasked randomized controlled trial. PARTICIPANTS: 700 vigorous infants of gestational age ≥34 weeks from through meconium stained amniotic fluid...
March 15, 2018: Indian Pediatrics
https://www.readbyqxmd.com/read/29628597/anesthetic-management-in-pediatric-patient-for-percutaneous-endoscopic-gastrostomy-with-mitochondrial-myopathy-leigh-syndrome
#8
Ebru Tarikçi Kiliç, Nelgin Gerenli, Mehmet Salim Akdemir, Necmi Onur Tastan, Egemen Atag
Leigh syndrome (LS) is a rare disease mainly affecting the central nervous system due to the abnormalities of mitochondrial energy generation and seen in early childhood with progressive loss of movement, mental abilities, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Anesthesia and surgery exacerbate the risks of aspiration, wheezing, and breathing difficulties. Tracheal irritability can be stimulated with the efforts of intubation. We report the anesthetic management of a rare case of an 11-year-old boy with a severe form of LS for percutaneous endoscopic gastrostomy insertion...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29626596/renal-histology-in-a-patient-with-tafro-syndrome-a-case-report
#9
Hiroki Mizuno, Akinari Sekine, Masahiko Oguro, Yoichi Oshima, Masahiro Kawada, Keiichi Sumida, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Rikako Hiramatsu, Eiko Hasegawa, Junichi Hoshino, Naoki Sawa, Takashi Fujii, Kenmei Takaichi, Kenichi Ohashi, Yoshifumi Ubara
An 84-year-old Japanese man was admitted due to anasarca, thrombocytopenia, systemic inflammation, and progressive renal insufficiency, resistant to diuretics, glucocorticoid therapy and plasma exchange. Renal biopsy showed diffuse endocapillary proliferation and mesangiolysis without any immune deposits. Tocilizumab suppressed systemic inflammation, resulting in improvement of anasarca and renal dysfunction, but thrombocytopenia persisted and platelet-associated IgG antibody was elevated. Though romiplostim was effective for thrombocytopenia, the patient died of aspiration pneumonia after cerebral hemorrhage...
April 4, 2018: Human Pathology
https://www.readbyqxmd.com/read/29621081/odontogenic-keratocysts-as-first-manifestation-of-nevoid-basal-cell-carcinoma-syndrome-surgical-management-and-immunohistochemical-analysis
#10
Jessica Luana Dos Santos, Renata Zoraida Rizental Delgado, Greison Rabelo de Oliveira, Ana Lúcia Carrinho Ayroza Rangel
Nevoid Basal Cell Carcinoma Syndrome (NBCCS), also known as Gorlin syndrome, is a rare autosomal dominant disorder, with no gender predilection. Individuals with NBCCS are commonly diagnosed between 17 and 35 years old and can present multiple basal cell carcinomas scattered throughout the body, presence of recurrent and early-onset odontogenic keratocysts (OKCs) and skeletal abnormalities. This article describes a case of a 13-year-old white boy who referred complaining of facial asymmetry. Extraoral examination revealed volumetric increase displacing the nasal ala from the right side and extended to the zygomatic bone...
April 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29607728/pseudogout-a-rare-manifestation-of-hungry-bone-syndrome-after-focused-parathyroidectomy
#11
C H Tai, H B Oh, J E Seet, K Y Ngiam
Pseudogout, also known as calcium pyrophosphate deposition disease, is a rheumatological condition arising from accumulation of calcium pyrophosphate dihydrate crystals in connective tissues. We present a case of a 56-year-old Bangladeshi woman who underwent focused right inferior parathyroidectomy for primary hyperparathyroidism from a right inferior parathyroid adenoma. On the first post-operative day, she complained of left elbow painful swelling with redness and warmth. Arthrocentesis of left elbow was done due to suspicion of septic arthritis...
April 1, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29602921/the-influence-of-the-manual-thrombus-aspiration-on-the-short-term-effectiveness-of-the-percutaneous-revascularization-in-patients-with-coronary-artery-thrombosis
#12
Maksim Y Sokolov, Dmytro I Besh, Olesya M Besh, Oleg I Rafaluk, Oleg O Kapustynskyy
OBJECTIVE: Introduction: Percutaneous coronary intervention (PCI) is one of the main issues in treatment of acute coronary syndrome with ST segment elevation (STEMI). The manual thrombus aspiration was believed to improve the results of intervention especially in patients with coronary thrombosis. The aim: To explore the influence of manual thrombus aspiration on the short-termed prognosis after PCI in patients with STEMI and visible coronary thrombosis. PATIENTS AND METHODS: Materials and methods: 50 patients with STEMI and visible coronary thrombosis were included for exploration...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29595115/efficacy-and-non-invasive-treatment-of-sialorrhea-in-the-goldenhar-syndrome
#13
R Marvulli, G A Gallo, L Mastromauro, P Fiore, G Ianieri, M Megna
Goldenhar syndrome (ocular-auricular-vertebral syndrome), a rare congenital condition arising from defects in the first and second brachial arches, consists in clinical variety of features ranging from facial abnormalities, ear-eye abnormalities, vertebral defects and congenital heart problems and severe obstructive sleep apnea. Due to craniofacial abnormalities, patients presents mechanical obstructive phenomena and sialorrhea that cause prone position, language's fastening, use of nasopharyngeal cannulas and tracheal intubation...
March 28, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/29590532/reply-to-the-impact-of-therapeutic-hypothermia-on-pulmonary-hemodynamics-of-meconium-aspiration-syndrome
#14
Daniele De Luca, David G Tingay, Anton van Kaam, Werther Brunow de Carvalho, Eva Valverde, Charles Christoph Roehr, Fabio Mosca, Piero G Matassa, Olivier Danhaive, Virgilio P Carnielli, Marco Piastra
No abstract text is available yet for this article.
March 28, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29590531/the-impact-of-therapeutic-hypothermia-on-pulmonary-hemodynamics-of-meconium-aspiration-syndrome
#15
Regan E Giesinger, Patrick J McNamara
No abstract text is available yet for this article.
March 28, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29576907/spinal-case-of-the-month-with-short-perspective-how-would-you-treat-this-l3-l4-synovial-cyst
#16
REVIEW
Nancy E Epstein
Background: In this new section, Case of the Month with Short Perspective from Surgical Neurology International, we want to see how various spine surgeons would approach different spinal pathologies. In this first case, an elderly male presented with 3 years of lower back pain and progressive neurogenic claudication with bilateral radiculopathy that had exacerbated over the prior 6 months. An outside physician performed a magnetic resonance (MR) study of the lumbar spine that showed a massive synovial cyst filling the spinal canal (e...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29575028/ultrasound-and-the-evaluation-of-pediatric-thyroid-malignancy-current-recommendations-for-diagnosis-and-follow-up
#17
REVIEW
Sarah Ogle, Alexa Merz, Ralitza Parina, Mahmoud Alsayed, Mira Milas
Ultrasound (US) plays a critical role in the evaluation, treatment, screening, and surveillance of thyroid malignancy in pediatric patients. This review aims to summarize recent advances in this topic. Improvements in imaging technology have amplified the advantage of US and US-guided fine-needle aspiration biopsy for thyroid nodule evaluation, cancer diagnosis, and surgical planning. Ultrasound has a definitive screening role for early cancer detection in high-risk patients, including those with a history of radiation exposure from childhood treatments, environmental radiation disasters, or hereditary/familial cancer syndromes...
March 25, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29559757/successful-use-of-extracorporeal-life-support-in-a-hematopoietic-stem-cell-transplant-patient-with-neuroblastoma
#18
Feifei Z Williams, Atul Vats, Thomas Cash, James D Fortenberry
Respiratory failure associated with hematopoietic stem cell transplantation (HSCT) has been considered a contraindication for use of extracorporeal membrane oxygenation (ECMO) at many centers. We describe a child with neuroblastoma and hypoxemic respiratory failure following HSCT who was successfully managed with veno-venous (VV) ECMO. The patient was an 18-month-old female with high-risk neuroblastoma status post tumor resection, chemotherapy, autologous HSCT, and primary site radiation. On day 113 posttransplant while receiving maintenance immunotherapy, she had an acute respiratory decompensation because of rhinovirus, aspiration pneumonia, and capillary leak syndrome...
March 2018: Journal of Extra-corporeal Technology
https://www.readbyqxmd.com/read/29543308/follicular-aspiration-versus-coasting-for-ovarian-hyper-stimulation-syndrome-prevention
#19
Nayla J Bushaqer, Nawal M Dayoub, Khalsa K AlHattali, Hisham A Ayyoub, Samaher S AlFaraj, Samar N Hassan
OBJECTIVE: To compare follicular reduction prior to human chorionic gonadotropin (HCG) trigger and coasting in terms of ovarian hyper-stimulation syndrome (OHSS) reduction, pregnancy, and cancellation rates in in vitro fertilization/ intracytoplasmic sperm injection (IVF/ICSI) cycles. METHODS:  This study was designed as a prospective study. The setting was the IVF unit at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. A total of 39 patients undergoing IVF/ICSI cycles, who were at risk of OHSS, 20 were put into a coasting group and 19 had follicular reduction instead...
March 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29531655/parvovirus-b19-triggered-acute-hemolytic-anemia-and-thrombocytopenia-in-a-child-with-evans-syndrome
#20
Panagiota Zikidou, Anastassia Grapsa, Zoe Bezirgiannidou, Athanassios Chatzimichael, Elpis Mantadakis
Background: Human parvovirus B19 (HPV-B19) is the etiologic agent of erythema infectiosum, of transient aplastic crises in individuals with underlying chronic hemolytic disorders, and of chronic pure red cell aplasia in immunocompromised individuals. Case report: We describe a 14-year-old girl with long-standing Evans syndrome, who presented with severe anemia, reticulocytopenia and thrombocytopenia. A bone marrow aspirate revealed severe erythroid hypoplasia along with the presence of giant pronormoblasts, while serological studies and real-time PCR of whole blood were positive for acute parvovirus B19 infection...
2018: Mediterranean Journal of Hematology and Infectious Diseases
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