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Peter parry

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https://www.readbyqxmd.com/read/28791140/individual-level-movement-bias-leads-to-the-formation-of-higher-order-social-structure-in-a-mobile-group-of-baboons
#1
Tyler R Bonnell, Parry M Clarke, S Peter Henzi, Louise Barrett
In mobile social groups, influence patterns driving group movement can vary between democratic and despotic. The arrival at any single pattern of influence is thought to be underpinned by both environmental factors and group composition. To identify the specific patterns of influence driving travel decision-making in a chacma baboon troop, we used spatially explicit data to extract patterns of individual movement bias. We scaled these estimates of individual-level bias to the level of the group by constructing an influence network and assessing its emergent structural properties...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28530131/a-combination-of-a-polycaprolactone-fumarate-scaffold-with-polyethylene-terephthalate-sutures-for-intra-articular-ligament-regeneration
#2
Joshua A Parry, Eric R Wagner, Peter L Kok, Mahrokh Dadsetan, Michael J Yaszemski, Andre J van Wijnen, Sanjeev Kakar
Intra-articular ligamentous injuries are typically unrepairable and have limited outcomes after graft reconstruction. A combination of porous polycaprolactone fumarate (PCLF) scaffolds with polyethylene terephthalate (PET) sutures was developed with the goal of regenerating intra-articular ligaments. Scaffolds were fabricated by injecting PCLF over three-dimensional-printed molds containing two strands of PET suture down its central pore followed by cross-linking. Scaffolds were seeded with human mesenchymal stem cells (MSCs) from adipose tissue...
June 29, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28523967/comparative-assessment-of-dna-methylation-patterns-between-reduced-representation-bisulfite-sequencing-and-sequenom-epityper-methylation-analysis
#3
Aniruddha Chatterjee, Erin C Macaulay, Antonio Ahn, Jackie L Ludgate, Peter A Stockwell, Rob J Weeks, Matthew F Parry, Timothy J Foster, Ingrid M Knarston, Michael R Eccles, Ian M Morison
AIM: Validation of sequencing-based DNA methylation data is an important step for meaningful translation of findings. However, there has been limited assessment of different platforms to validate methylation data from next generation sequencing. METHODS: We performed a comparative methylation analysis between the genome-wide platform of reduced representation bisulfite sequencing with a targeted, Sequenom EpiTyper platform (four genes were analyzed in 15 cell lines covering 52 CpG sites)...
May 19, 2017: Epigenomics
https://www.readbyqxmd.com/read/28495793/usp7-inhibition-alters-homologous-recombination-repair-and-targets-cll-cells-independently-of-atm-p53-functional-status
#4
Angelo Agathanggelou, Edward Smith, Nicholas J Davies, Marwan Kwok, Anastasia Zlatanou, Ceri E Oldreive, Jingwen Mao, David Da Costa, Sina Yadollahi, Tracey Perry, Pamela Kearns, Anna Skowronska, Elliot Yates, Helen Parry, Peter Hillmen, Celine Reverdy, Remi Delansorne, Shankara Paneesha, Guy Pratt, Paul Moss, A Malcolm R Taylor, Grant S Stewart, Tatjana Stankovic
The role of deubiquitylase ubiquitin-specific protease 7 (USP7) in the regulation of the p53-dependent DNA damage response (DDR) pathway is well established. Whereas previous studies have mostly focused on the mechanisms underlying how USP7 directly controls p53 stability, we recently showed that USP7 modulates the stability of the DNA damage responsive E3 ubiquitin ligase RAD18. This suggests that targeting USP7 may have therapeutic potential even in tumors with defective p53 or ibrutinib resistance. To test this hypothesis, we studied the effect of USP7 inhibition in chronic lymphocytic leukemia (CLL) where the ataxia telangiectasia mutated (ATM)-p53 pathway is inactivated with relatively high frequency, leading to treatment resistance and poor clinical outcome...
July 13, 2017: Blood
https://www.readbyqxmd.com/read/28424049/findings-in-young-adults-at-colonoscopy-from-a-hospital-service-database-audit
#5
Stephanie Wong, Ilmars Lidums, Christophe Rosty, Andrew Ruszkiewicz, Susan Parry, Aung Ko Win, Yoko Tomita, Sina Vatandoust, Amanda Townsend, Dainik Patel, Jennifer E Hardingham, David Roder, Eric Smith, Paul Drew, Julie Marker, Wendy Uylaki, Peter Hewett, Daniel L Worthley, Erin Symonds, Graeme P Young, Timothy J Price, Joanne P Young
BACKGROUND: Colorectal cancer (CRC) diagnosed at <50 years is predominantly located in the distal colon and rectum. Little is known about which lesion subtypes may serve as CRC precursors in young adults. The aim of this work was to document the prevalence and histological subtype of lesions seen in patients aged <50 years, and any associated clinical features. METHODS: An audit of the colonoscopy database at The Queen Elizabeth Hospital in Adelaide, South Australia over a 12-month period was undertaken...
April 19, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28210771/factors-influencing-physical-activity-and-rehabilitation-in-survivors-of-critical-illness-a-systematic-review-of-quantitative-and-qualitative-studies
#6
REVIEW
Selina M Parry, Laura D Knight, Bronwen Connolly, Claire Baldwin, Zudin Puthucheary, Peter Morris, Jessica Mortimore, Nicholas Hart, Linda Denehy, Catherine L Granger
PURPOSE: To identify, evaluate and synthesise studies examining the barriers and enablers for survivors of critical illness to participate in physical activity in the ICU and post-ICU settings from the perspective of patients, caregivers and healthcare providers. METHODS: Systematic review of articles using five electronic databases: MEDLINE, CINAHL, EMBASE, Cochrane Library, Scopus. Quantitative and qualitative studies that were published in English in a peer-reviewed journal and assessed barriers or enablers for survivors of critical illness to perform physical activity were included...
April 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28166536/ancestral-morphology-of-crown-group-molluscs-revealed-by-a-new-ordovician-stem-aculiferan
#7
Jakob Vinther, Luke Parry, Derek E G Briggs, Peter Van Roy
Exceptionally preserved fossils provide crucial insights into extinct body plans and organismal evolution. Molluscs, one of the most disparate animal phyla, radiated rapidly during the early Cambrian period (approximately 535-520 million years ago (Ma)). The problematic fossil taxa Halkieria and Orthrozanclus (grouped in Sachitida) have been assigned variously to stem-group annelids, brachiopods, stem-group molluscs or stem-group aculiferans (Polyplacophora and Aplacophora), but their affinities have remained controversial owing to a lack of preserved diagnostic characters...
February 23, 2017: Nature
https://www.readbyqxmd.com/read/28095408/patient-safety-incidents-involving-sick-children-in-primary-care-in-england-and-wales-a-mixed-methods-analysis
#8
Philippa Rees, Adrian Edwards, Colin Powell, Peter Hibbert, Huw Williams, Meredith Makeham, Ben Carter, Donna Luff, Gareth Parry, Anthony Avery, Aziz Sheikh, Liam Donaldson, Andrew Carson-Stevens
BACKGROUND: The UK performs poorly relative to other economically developed countries on numerous indicators of care quality for children. The contribution of iatrogenic harm to these outcomes is unclear. As primary care is the first point of healthcare contact for most children, we sought to investigate the safety of care provided to children in this setting. METHODS AND FINDINGS: We undertook a mixed methods investigation of reports of primary care patient safety incidents involving sick children from England and Wales' National Reporting and Learning System between 1 January 2005 and 1 December 2013...
January 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28070282/the-database-of-the-predicts-projecting-responses-of-ecological-diversity-in-changing-terrestrial-systems-project
#9
Lawrence N Hudson, Tim Newbold, Sara Contu, Samantha L L Hill, Igor Lysenko, Adriana De Palma, Helen R P Phillips, Tamera I Alhusseini, Felicity E Bedford, Dominic J Bennett, Hollie Booth, Victoria J Burton, Charlotte W T Chng, Argyrios Choimes, David L P Correia, Julie Day, Susy Echeverría-Londoño, Susan R Emerson, Di Gao, Morgan Garon, Michelle L K Harrison, Daniel J Ingram, Martin Jung, Victoria Kemp, Lucinda Kirkpatrick, Callum D Martin, Yuan Pan, Gwilym D Pask-Hale, Edwin L Pynegar, Alexandra N Robinson, Katia Sanchez-Ortiz, Rebecca A Senior, Benno I Simmons, Hannah J White, Hanbin Zhang, Job Aben, Stefan Abrahamczyk, Gilbert B Adum, Virginia Aguilar-Barquero, Marcelo A Aizen, Belén Albertos, E L Alcala, Maria Del Mar Alguacil, Audrey Alignier, Marc Ancrenaz, Alan N Andersen, Enrique Arbeláez-Cortés, Inge Armbrecht, Víctor Arroyo-Rodríguez, Tom Aumann, Jan C Axmacher, Badrul Azhar, Adrián B Azpiroz, Lander Baeten, Adama Bakayoko, András Báldi, John E Banks, Sharad K Baral, Jos Barlow, Barbara I P Barratt, Lurdes Barrico, Paola Bartolommei, Diane M Barton, Yves Basset, Péter Batáry, Adam J Bates, Bruno Baur, Erin M Bayne, Pedro Beja, Suzan Benedick, Åke Berg, Henry Bernard, Nicholas J Berry, Dinesh Bhatt, Jake E Bicknell, Jochen H Bihn, Robin J Blake, Kadiri S Bobo, Roberto Bóçon, Teun Boekhout, Katrin Böhning-Gaese, Kevin J Bonham, Paulo A V Borges, Sérgio H Borges, Céline Boutin, Jérémy Bouyer, Cibele Bragagnolo, Jodi S Brandt, Francis Q Brearley, Isabel Brito, Vicenç Bros, Jörg Brunet, Grzegorz Buczkowski, Christopher M Buddle, Rob Bugter, Erika Buscardo, Jörn Buse, Jimmy Cabra-García, Nilton C Cáceres, Nicolette L Cagle, María Calviño-Cancela, Sydney A Cameron, Eliana M Cancello, Rut Caparrós, Pedro Cardoso, Dan Carpenter, Tiago F Carrijo, Anelena L Carvalho, Camila R Cassano, Helena Castro, Alejandro A Castro-Luna, Cerda B Rolando, Alexis Cerezo, Kim Alan Chapman, Matthieu Chauvat, Morten Christensen, Francis M Clarke, Daniel F R Cleary, Giorgio Colombo, Stuart P Connop, Michael D Craig, Leopoldo Cruz-López, Saul A Cunningham, Biagio D'Aniello, Neil D'Cruze, Pedro Giovâni da Silva, Martin Dallimer, Emmanuel Danquah, Ben Darvill, Jens Dauber, Adrian L V Davis, Jeff Dawson, Claudio de Sassi, Benoit de Thoisy, Olivier Deheuvels, Alain Dejean, Jean-Louis Devineau, Tim Diekötter, Jignasu V Dolia, Erwin Domínguez, Yamileth Dominguez-Haydar, Silvia Dorn, Isabel Draper, Niels Dreber, Bertrand Dumont, Simon G Dures, Mats Dynesius, Lars Edenius, Paul Eggleton, Felix Eigenbrod, Zoltán Elek, Martin H Entling, Karen J Esler, Ricardo F de Lima, Aisyah Faruk, Nina Farwig, Tom M Fayle, Antonio Felicioli, Annika M Felton, Roderick J Fensham, Ignacio C Fernandez, Catarina C Ferreira, Gentile F Ficetola, Cristina Fiera, Bruno K C Filgueiras, Hüseyin K Fırıncıoğlu, David Flaspohler, Andreas Floren, Steven J Fonte, Anne Fournier, Robert E Fowler, Markus Franzén, Lauchlan H Fraser, Gabriella M Fredriksson, Geraldo B Freire, Tiago L M Frizzo, Daisuke Fukuda, Dario Furlani, René Gaigher, Jörg U Ganzhorn, Karla P García, Juan C Garcia-R, Jenni G Garden, Ricardo Garilleti, Bao-Ming Ge, Benoit Gendreau-Berthiaume, Philippa J Gerard, Carla Gheler-Costa, Benjamin Gilbert, Paolo Giordani, Simonetta Giordano, Carly Golodets, Laurens G L Gomes, Rachelle K Gould, Dave Goulson, Aaron D Gove, Laurent Granjon, Ingo Grass, Claudia L Gray, James Grogan, Weibin Gu, Moisès Guardiola, Nihara R Gunawardene, Alvaro G Gutierrez, Doris L Gutiérrez-Lamus, Daniela H Haarmeyer, Mick E Hanley, Thor Hanson, Nor R Hashim, Shombe N Hassan, Richard G Hatfield, Joseph E Hawes, Matt W Hayward, Christian Hébert, Alvin J Helden, John-André Henden, Philipp Henschel, Lionel Hernández, James P Herrera, Farina Herrmann, Felix Herzog, Diego Higuera-Diaz, Branko Hilje, Hubert Höfer, Anke Hoffmann, Finbarr G Horgan, Elisabeth Hornung, Roland Horváth, Kristoffer Hylander, Paola Isaacs-Cubides, Hiroaki Ishida, Masahiro Ishitani, Carmen T Jacobs, Víctor J Jaramillo, Birgit Jauker, F Jiménez Hernández, McKenzie F Johnson, Virat Jolli, Mats Jonsell, S Nur Juliani, Thomas S Jung, Vena Kapoor, Heike Kappes, Vassiliki Kati, Eric Katovai, Klaus Kellner, Michael Kessler, Kathryn R Kirby, Andrew M Kittle, Mairi E Knight, Eva Knop, Florian Kohler, Matti Koivula, Annette Kolb, Mouhamadou Kone, Ádám Kőrösi, Jochen Krauss, Ajith Kumar, Raman Kumar, David J Kurz, Alex S Kutt, Thibault Lachat, Victoria Lantschner, Francisco Lara, Jesse R Lasky, Steven C Latta, William F Laurance, Patrick Lavelle, Violette Le Féon, Gretchen LeBuhn, Jean-Philippe Légaré, Valérie Lehouck, María V Lencinas, Pia E Lentini, Susan G Letcher, Qi Li, Simon A Litchwark, Nick A Littlewood, Yunhui Liu, Nancy Lo-Man-Hung, Carlos A López-Quintero, Mounir Louhaichi, Gabor L Lövei, Manuel Esteban Lucas-Borja, Victor H Luja, Matthew S Luskin, M Cristina MacSwiney G, Kaoru Maeto, Tibor Magura, Neil Aldrin Mallari, Louise A Malone, Patrick K Malonza, Jagoba Malumbres-Olarte, Salvador Mandujano, Inger E Måren, Erika Marin-Spiotta, Charles J Marsh, E J P Marshall, Eliana Martínez, Guillermo Martínez Pastur, David Moreno Mateos, Margaret M Mayfield, Vicente Mazimpaka, Jennifer L McCarthy, Kyle P McCarthy, Quinn S McFrederick, Sean McNamara, Nagore G Medina, Rafael Medina, Jose L Mena, Estefania Mico, Grzegorz Mikusinski, Jeffrey C Milder, James R Miller, Daniel R Miranda-Esquivel, Melinda L Moir, Carolina L Morales, Mary N Muchane, Muchai Muchane, Sonja Mudri-Stojnic, A Nur Munira, Antonio Muoñz-Alonso, B F Munyekenye, Robin Naidoo, A Naithani, Michiko Nakagawa, Akihiro Nakamura, Yoshihiro Nakashima, Shoji Naoe, Guiomar Nates-Parra, Dario A Navarrete Gutierrez, Luis Navarro-Iriarte, Paul K Ndang'ang'a, Eike L Neuschulz, Jacqueline T Ngai, Violaine Nicolas, Sven G Nilsson, Norbertas Noreika, Olivia Norfolk, Jorge Ari Noriega, David A Norton, Nicole M Nöske, A Justin Nowakowski, Catherine Numa, Niall O'Dea, Patrick J O'Farrell, William Oduro, Sabine Oertli, Caleb Ofori-Boateng, Christopher Omamoke Oke, Vicencio Oostra, Lynne M Osgathorpe, Samuel Eduardo Otavo, Navendu V Page, Juan Paritsis, Alejandro Parra-H, Luke Parry, Guy Pe'er, Peter B Pearman, Nicolás Pelegrin, Raphaël Pélissier, Carlos A Peres, Pablo L Peri, Anna S Persson, Theodora Petanidou, Marcell K Peters, Rohan S Pethiyagoda, Ben Phalan, T Keith Philips, Finn C Pillsbury, Jimmy Pincheira-Ulbrich, Eduardo Pineda, Joan Pino, Jaime Pizarro-Araya, A J Plumptre, Santiago L Poggio, Natalia Politi, Pere Pons, Katja Poveda, Eileen F Power, Steven J Presley, Vânia Proença, Marino Quaranta, Carolina Quintero, Romina Rader, B R Ramesh, Martha P Ramirez-Pinilla, Jai Ranganathan, Claus Rasmussen, Nicola A Redpath-Downing, J Leighton Reid, Yana T Reis, José M Rey Benayas, Juan Carlos Rey-Velasco, Chevonne Reynolds, Danilo Bandini Ribeiro, Miriam H Richards, Barbara A Richardson, Michael J Richardson, Rodrigo Macip Ríos, Richard Robinson, Carolina A Robles, Jörg Römbke, Luz Piedad Romero-Duque, Matthias Rös, Loreta Rosselli, Stephen J Rossiter, Dana S Roth, T'ai H Roulston, Laurent Rousseau, André V Rubio, Jean-Claude Ruel, Jonathan P Sadler, Szabolcs Sáfián, Romeo A Saldaña-Vázquez, Katerina Sam, Ulrika Samnegård, Joana Santana, Xavier Santos, Jade Savage, Nancy A Schellhorn, Menno Schilthuizen, Ute Schmiedel, Christine B Schmitt, Nicole L Schon, Christof Schüepp, Katharina Schumann, Oliver Schweiger, Dawn M Scott, Kenneth A Scott, Jodi L Sedlock, Steven S Seefeldt, Ghazala Shahabuddin, Graeme Shannon, Douglas Sheil, Frederick H Sheldon, Eyal Shochat, Stefan J Siebert, Fernando A B Silva, Javier A Simonetti, Eleanor M Slade, Jo Smith, Allan H Smith-Pardo, Navjot S Sodhi, Eduardo J Somarriba, Ramón A Sosa, Grimaldo Soto Quiroga, Martin-Hugues St-Laurent, Brian M Starzomski, Constanti Stefanescu, Ingolf Steffan-Dewenter, Philip C Stouffer, Jane C Stout, Ayron M Strauch, Matthew J Struebig, Zhimin Su, Marcela Suarez-Rubio, Shinji Sugiura, Keith S Summerville, Yik-Hei Sung, Hari Sutrisno, Jens-Christian Svenning, Tiit Teder, Caragh G Threlfall, Anu Tiitsaar, Jacqui H Todd, Rebecca K Tonietto, Ignasi Torre, Béla Tóthmérész, Teja Tscharntke, Edgar C Turner, Jason M Tylianakis, Marcio Uehara-Prado, Nicolas Urbina-Cardona, Denis Vallan, Adam J Vanbergen, Heraldo L Vasconcelos, Kiril Vassilev, Hans A F Verboven, Maria João Verdasca, José R Verdú, Carlos H Vergara, Pablo M Vergara, Jort Verhulst, Massimiliano Virgilio, Lien Van Vu, Edward M Waite, Tony R Walker, Hua-Feng Wang, Yanping Wang, James I Watling, Britta Weller, Konstans Wells, Catrin Westphal, Edward D Wiafe, Christopher D Williams, Michael R Willig, John C Z Woinarski, Jan H D Wolf, Volkmar Wolters, Ben A Woodcock, Jihua Wu, Joseph M Wunderle, Yuichi Yamaura, Satoko Yoshikura, Douglas W Yu, Andrey S Zaitsev, Juliane Zeidler, Fasheng Zou, Ben Collen, Rob M Ewers, Georgina M Mace, Drew W Purves, Jörn P W Scharlemann, Andy Purvis
The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a large, reasonably representative database of comparable samples of biodiversity from multiple sites that differ in the nature or intensity of human impacts relating to land use. We have used this evidence base to develop global and regional statistical models of how local biodiversity responds to these measures. We describe and make freely available this 2016 release of the database, containing more than 3...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/27902947/what-factors-affect-implementation-of-early-rehabilitation-into-intensive-care-unit-practice-a-qualitative-study-with-clinicians
#10
Selina M Parry, Louisa Remedios, Linda Denehy, Laura D Knight, Lisa Beach, Thomas C Rollinson, Sue Berney, Zudin A Puthucheary, Peter Morris, Catherine L Granger
PURPOSE: To identify the barriers and enablers that influence clinicians' implementation of early rehabilitation in critical care. MATERIALS AND METHODS: Qualitative study involving 26 multidisciplinary participants who were recruited using purposive sampling. Four focus groups were conducted using semistructured questions to explore attitudes, beliefs, and experiences. Data were transcribed verbatim and thematic analysis was performed. RESULTS: Six themes emerged, as follows: (1) the clinicians' expectations and knowledge (including rationale for rehabilitation, perceived benefits, and experience), (2) the evidence for and application of rehabilitation (including beliefs regarding when to intervene), (3) patient factors (including prognosis, sedation, delirium, cooperation, motivation, goals, and family), (4) safety considerations (including physiological stability and presence of devices or lines), (5) environmental influences (staffing, resources, equipment, time, and competing priorities), and (6) culture and teamwork...
April 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/27742425/relation-among-clot-burden-right-sided-heart-strain-and-adverse-events-after-acute-pulmonary-embolism
#11
Praveen Hariharan, David M Dudzinski, Rachel Rosovsky, Farris Haddad, Peter MacMahon, Blair Parry, Yuchiao Chang, Christopher Kabrhel
Computed tomography pulmonary angiogram (CTPA) provides a volumetric assessment of clot burden in acute pulmonary embolism (PE). However, it is unclear if clot burden is associated with right-sided heart strain (RHS) or adverse clinical events (ACE). We prospectively enrolled Emergency Department patients with PE (in CTPA) from 2008 to 2011. We assigned 1 to 9 points as clot burden score, based on whether emboli were saddle, central, lobar, segmental, and subsegmental. We evaluated a novel score (the "CT-PASS") based on the sum (in millimeters) of the largest filling defects in the right and left pulmonary vasculature...
November 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27708812/a-mixed-method-study-of-pain-management-practice-in-a%C3%A2-uk-children-s-hospital-identification-of-barriers-and-developing-strategies-to-maintain-effective-in-patient-paediatric-pain-management
#12
Kate Beckett, Ellen M Henderson, Sarah Parry, Peter Stoddart, Margaret Fletcher
AIM: To assess Acute Pain Service and paediatric pain management efficacy in a UK specialist paediatric hospital to inform wider recommendations for future sustainability. BACKGROUND: UK paediatric acute pain services vary. Although comprehensive pain management guidelines exist, consensus on the best model of care is lacking. Worldwide, medical and pharmacological advances and rapid patient turnover have increased the challenges of managing hospitalized children's pain...
January 2016: Nursing Open
https://www.readbyqxmd.com/read/27686459/esicm-lives-2016-part-three-milan-italy-1-5-october-2016
#13
T Velasquez, G Mackey, J Lusk, U G Kyle, T Fontenot, P Marshall, L S Shekerdemian, J A Coss-Bu, A Nishigaki, T Yatabe, T Tamura, K Yamashita, M Yokoyama, J C Ruiz-Rodriguez, B Encina, R Belmonte, I Troncoso, P Tormos, M Riveiro, J Baena, A Sanchez, J Bañeras, J Cordón, N Duran, A Ruiz, J Caballero, X Nuvials, J Riera, J Serra, A M F Rutten, S N M van Ieperen, E P H M Der Kinderen, T Van Logten, L Kovacikova, P Skrak, M Zahorec, U G Kyle, A Akcan-Arikan, J C Silva, G Mackey, J Lusk, M Goldsworthy, L S Shekerdemian, J A Coss-Bu, D Wood, D Harrison, R Parslow, P Davis, J Pappachan, S Goodwin, P Ramnarayan, S Chernyshuk, H Yemets, V Zhovnir, S M Pulitano', S De Rosa, A Mancino, G Villa, F Tosi, P Franchi, G Conti, B Patel, H Khine, A Shah, D Sung, L Singer, S Haghbin, S Inaloo, Z Serati, M Idei, T Nomura, N Yamamoto, Y Sakai, T Yoshida, Y Matsuda, Y Yamaguchi, S Takaki, O Yamaguchi, T Goto, N Longani, S Medar, I R Abdel-Aal, A S El Adawy, H M E H Mohammed, A N Mohamed, S M Parry, L D Knight, L Denehy, N De Morton, C E Baldwin, D Sani, G Kayambu, V Z M da Silva, P Phongpagdi, Z A Puthucheary, C L Granger, J E Rydingsward, C M Horkan, K B Christopher, D McWilliams, C Jones, E Reeves, G Atkins, C Snelson, L M Aitken, J Rattray, J Kenardy, A M Hull, A Ullman, R Le Brocque, M Mitchell, C Davis, B Macfarlane, J C Azevedo, L L Rocha, F F M De Freitas, A M Cavalheiro, N M Lucinio, M S Lobato, G Ebeling, A Kraegpoeth, E Laerkner, I De Brito-Ashurst, C White, S Gregory, L G Forni, E Flowers, A Curtis, C A Wood, K Siu, K Venkatesan, J B H Muhammad, L Ng, E Seet, N Baptista, A Escoval, E Tomas, R Agrawal, R Mathew, A Varma, E Dima, E Charitidou, E Perivolioti, M Pratikaki, C Vrettou, A Giannopoulos, S Zakynthinos, C Routsi, E Atchade, S Houzé, S Jean-Baptiste, G Thabut, C Genève, S Tanaka, B Lortat-Jacob, P Augustin, M Desmard, P Montravers, F J González de Molina, S Barbadillo, R Alejandro, F Álvarez-Lerma, J Vallés, R M Catalán, E Palencia, A Jareño, R M Granada, M L Ignacio, N Cui, D Liu, H Wang, L Su, H Qiu, R Li, K Jaffal, A Rouzé, J Poissy, B Sendid, S Nseir, E Paramythiotou, M Rizos, F Frantzeskaki, A Antoniadou, S Vourli, L Zerva, A Armaganidis, J Riera, J Gottlieb, M Greer, O Wiesner, M Martínez, M Acuña, J Rello, T Welte, E Atchade, T Mignot, S Houzé, S Jean-Baptiste, G Thabut, B Lortat-Jacob, S Tanaka, P Augustin, M Desmard, P Montravers, S Soussi, E Dudoignon, A Ferry, M Chaussard, M Benyamina, A Alanio, S Touratier, M Chaouat, M Lafaurie, M Mimoun, A Mebazaa, M Legrand, M A Sheils, C Patel, L Mohankumar, N Akhtar, S K Pacheco Noriega, N Navarrete Aldana, J L Ávila León, J Durand Baquero, F Fernández Bernal, E Ahmadnia, J S Hadley, M Millar, D Hall, H Hewitt, H Yasuda, M Sanui, T Komuro, S Kawano, K Andoh, H Yamamoto, E Noda, J Hatakeyama, N Saitou, H Okamoto, A Kobayashi, T Takei, S Matsukubo, H B Rotzel, A Serrano Lázaro, D Aguillón Prada, M Rodriguez Gimillo, O Diaz Barinas, M L Blasco Cortes, J Ferreres Franco, J M Segura Roca, A Carratalá, B Gonçalves, R Turon, A Mendes, F Miranda, P J Mata, D Cavalcanti, N Melo, P Lacerda, P Kurtz, C Righy, L E de la Cruz Rosario, S P Gómez Lesmes, J C García Romero, A N García Herrera, E D Díaz Pertuz, M J Gómez Sánchez, E Regidor Sanz, J Barado Hualde, A Ansotegui Hernández, J M Guergué Irazabal, V Spatenkova, O Bradac, P Suchomel, T Urli, E Heusch Lazzeri, R Aspide, M Zanello, L Perez-Borrero, J M Garcia-Alvarez, M D Arias-Verdu, E Aguilar-Alonso, R Rivera-Fernandez, J Mora-Ordoñez, C De La Fuente-Martos, E Castillo-Lorente, F Guerrero-Lopez, S P Gómez Lesmes, L E De la Cruz Rosario, E D Díaz Pertuz, A Ansotegui Hernández, J C García Romero, M J Gómez Sánchez, A N García Herrera, J Roldán Ramírez, E Regidor Sanz, J Barado Hualde, J P Tirapu León, L Navarro-Guillamón, S Cordovilla-Guardia, A Iglesias-Santiago, F Guerrero-López, E Fernández-Mondéjar, A Vidal, M Perez, A Juez, N Arias, L Colino, J L Perez, H Pérez, P Calpe, M A Alcala, D Robaglia, C Perez, S K Lan, M M Cunha, 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Theodorakopoulou, M Stamouli, K Gkirkas, I K Dimopoulou, S Makiko, M Tsunoda, M Kang, J Yuzawa, N Akiduki, M Namiki, M Takeda, A Yaguchi, S Preau, M Ambler, A Sigurta, S Saeed, M Singer, S Jochmans, J Chelly, L V P Vong, O Sy, J Serbource-Goguel, N Rolin, C M Weyer, R I Abdallah, C Adrie, C Vinsonneau, M Monchi, U Mayr, W Huber, E Karsten, T Lahmer, P Thies, B Henschel, G Fischer, R M Schmid, O Ediboglu, S Ataman, I Naz, G Yaman, C Kirakli, P L Su, P S Kou, W C Lin, C W Chen, J A Benítez Lozano, P Carmona Sánchez, J E Barrueco Francioni, F Ruiz Ferrón, J M Serrano Simón, Z Riad, M Mezidi, M Aublanc, S Perinel, F Lissonde, A Louf-Durier, H Yonis, R Tapponnier, J C Richard, B Louis, C Guérin, M Mezidi, H Yonis, M Aublanc, F Lissonde, A Louf-Durier, S Perinel, R Tapponnier, J C Richard, C Guérin, K Marmanidou, M Oikonomou, C Nouris, C Loizou, E Soilemezi, D Matamis, P Somhorst, D Gommers, K Hayashi, T Hirayama, T Yumoto, K Tsukahara, A Iida, N Nosaka, K Sato, T Ugawa, A Nakao, Y Ujike, S Hirohata, F Mojoli, F Torriglia, M Giannantonio, A Orlando, S Bianzina, G Tavazzi, S Mongodi, M Pozzi, G A Iotti, A Braschi, D Jansen, S Gadgil, J Doorduin, L Roesthuis, J G van der Hoeven, L M A Heunks, G Q Chen, X M Sun, X He, Y L Yang, Z H Shi, M Xu, J X Zhou, S M Pereira, M R Tucci, B F F Tonelotto, C M Simoes, C C A Morais, M S Pompeo, F U Kay, M B P Amato, J E Vieira, S Suzuki, Y Mihara, Y Hikasa, S Okahara, H Morimatsu, H M Kwon, Y J Moon, S H Lee, K W Jung, W J Shin, I G Jun, J G Song, G S Hwang, S Lee, Y J Moon, H M Kwon, K Jung, W J Shin, I G Jun, J G Song, G S Hwang, A Ramelli, T Manca, F Corradi, C Brusasco, F Nicolini, T Gherli, R Brianti, P Fanzaghi, A Vezzani, B A Tudor, D A Klaus, D Lebherz-Eichinger, C Lechner, C Schwarz, M Bodingbauer, R Seemann, K Kaczirek, E Fleischmann, G A Roth, C G Krenn, A Malyshev, S Sergey, Y Yamaguchi, T Nomura, E Yoshitake, M Idei, T Yoshida, S Takaki, O Yamaguchi, M Kaneko, T Goto, N Tencé, I Zaien, M Wolf, P Trouiller, F M Jacobs, J M Kelly, P Veigas, S Hollands, A Min, S Rizoli, C M Coronado Robles, M A Montes de Oca Sandoval, O Tarabrin, D Gavrychenko, G Mazurenko, P Tarabrin, I Palacios Garcia, A Diaz Martin, M Casado Mendez, V Arellano Orden, R Leal Noval, C McCue, L Gemmell, A MacKay, J Luján, P Villa, B Llorente, R Molina, L Alcázar, C Arenillas Juanas, S Rogero, T Pascual, J A Cambronero, P Matía Almudévar, J Palamidessi Domínguez, S Alcántara Carmona, D Palacios Castañeda, A Naharro Abellán, A Pérez Lucendo, L Pérez Pérez, R Fernández Rivas, N Martínez Sanz, J Veganzones Ramos, P Rodríguez Villamizar, S Javadpour, N Kalani, T Amininejad, S Jamali, S Sobhanian, A Laurent, M Bonnet, R Rigal, P Aslanian, P Hebert, G Capellier, M R Diaz Contreras, C Rodriguez Mejías, F C Santiago Ruiz, M Duro Lombardo, J Castaño Perez, E Aguayo de Hoyos, A Estella, R Viciana, L Perez Fontaiña, T Rico, V Perez Madueño, M Recuerda, L Fernández, A Sandiumenge, S Bonet, C Mazo, M Rubiera, J C Ruiz-Rodríguez, R M Gracia, E Espinel, T Pont, A Kotsopoulos, N Jansen, W F Abdo, A Gopcevic, Z Gavranovic, M Vucic, M Zlatic Glogoski, L Videc Penavic, A Horvat, L Martin-Villen, J J Egea-Guerero, J Revuelto-Rey, T Aldabo-Pallas, E Correa-Chamorro, A I Gallego-Corpa, P Ruiz Del Portal-Ruiz Granados, V Faivre, L Wildenberg, B Huot, A C Lukaszewicz, M Simsir, C Mengelle, D Payen, N Martinez Sanz, B Lobo Valbuena, M Valdivia de la Fuente, P Matía Almudena, L Pérez Pérez, S Alcántara Carmona, A Navarro Abellán, I Fernández Simón, J J Rubio Muñoz, J Veganzones Ramos, S Alcantara Carmona, P Matia Almudevar, A Naharro Abellan, M A Perez Lucendo, L Perez Perez, J Palamidessi Dominguez, R Fernandez Rivas, P Rodriguez Villamizar, S Wee, C Ong, Y H Lau, Y Wong, M E Banderas-Bravo, V Olea-Jiménez, J M Mora-Ordóñez, C Gómez-Jiménez, J L Muñoz-Muñoz, J Vallejo-Báez, D Daga-Ruiz, M Lebrón-Gallardo, G Rialp, J M Raurich, I Morán, M C Martín, G Heras, A Mas, I Vallverdú, S Hraiech, J Bourenne, C Guervilly, J M Forel, M Adda, P Sylla, A Mouaci, M Gainnier, L Papazian, P R Bauer, A Kumbamu, M E Wilson, J K Pannu, J S Egginton, R Kashyap, O Gajic, S Yoshihiro, M Sakuraya, M Hayakawa, A Hirata, N Kawamura, T Tsutui, K Yoshida, Y Hashimoto, C H Chang, H C Hu, L C Chiu, C Y Hung, S H Li, K C Kao, S Sibley, J Drover, C D'Arsigny, C Parker, D Howes, S Moffatt, J Erb, R Ilan, D Messenger, I Ball, J G Boyd, M Harrison, S Ridi, J Muscedere, A H Andrade, R C Costa, V A Souza, V Gonzalez, V Amorim, F Rolla, C A C Abreu Filho, R Miranda, S Atchasiri, P Buranavanich, T Wathanawatthu, S Suwanpasu, C Bureau, C Rolland-Debord, T Poitou, M Clavel, S Perbet, N Terzi, A Kouatchet, T Similowski, A Demoule, P Diaz, J Nunes, S Escórcio, G Silva, S Chaves, M Jardim, M Câmara, N Fernandes, R Duarte, J J Jardim, C A Pereira, J J Nóbrega, C M Chen, C C Lai, K C Cheng, W Chou, S J Lee, Y S Cha, W Y Lee, M Onodera, E Nakataki, J Oto, H Imanaka, M Nishimura, A Khadjibaev, D Sabirov, A Rosstalnaya, R Akalaev, F Parpibaev, E Antonucci, P Rossini, S Gandolfi, E Montini, S Orlando, M van Nes, F Karachi, S Hanekom, A H Andrade, U V Pereira, C A C Abreu Filho, R C Costa, M S W Parkin, M Moore, A H Andrade, R C Costa, K V Silva Carvalho, C A C Abreu Filho, H J Min, H J Kim, D S Lee, Y Y Choi, E Y Lee, I Song, D J Kim, Y Y E, J W Kim, J S Park, Y J Cho, J H Lee, J W Suh, Y H Jo, K S Kim, Y J Lee, J Ferrero-Calleja, D Merino-Vega, A I González-Jiménez, M Sigcha Sigcha, A Hernández-Tejedor, A Martin-Vivas, Á Gabán-Díez, R Ruiz-de Luna, N De la Calle-Pedrosa, I Temprano-Gómez, D Afonso-Rivero, J I Pellin-Ariño, A Algora-Weber, R R L Fumis, A B Ferraz, J M Vieira Junior, H Kirca, O Cakin, M Unal, H Mutlu, A Ramazanoglu, M Cengiz, E A Nicolini, F G F Pelisson, R S Nunes, S L da Silva, M M Carreira, F Bellissimo-Rodrigues, M A Ferez, A Basile-Filho, H C Chao, C M Chen, L Chen, M Hravnak, G Clermont, M Pinsky, A Dubrawski, J Luján Varas, R Molina Montero, L Alcázar Sánchez-Elvira, P Villa Díaz, C Pintado Delgado, B Llorente Ruiz, A Pardo Guerrero, J A Cambronero Galache, H Sherif, H Hassanin, R El Hossainy, W Samy, H Ly, H David, P Burtin, C Charpentier, M Barral, P Courant, E Fournel, L Gaide-Chevronnay, M Durand, P Albaladejo, J F Payen, O Chavanon, A Blandino Ortiz, S Pozzebon, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, F Fumagalli, S Scala, R Affatato, M De Maglie, D Zani, D Novelli, C Marra, A Luciani, D De Zani, M Luini, T Letizia, D Pravettoni, L Staszewsky, S Masson, A Belloli, M Di Giancamillo, E Scanziani, R Latini, G Ristagno, Y C Kye, G J Suh, W Y Kwon, K S Kim, K M Yu, G Babini, G Ristagno, L Grassi, F Fumagalli, S Bendel, M De Maglie, R Affatato, S Masson, R Latini, E Scanziani, M Reinikainen, M Skrifvars, F Kappler, M Blobner, S J Schaller, A Roasio, E Costanzo, S Cardellino, E Iesu, F Zama Cavicchi, V Fontana, L Nobile, J L Vincent, J Creteur, F S Taccone, M Park, K M You, G J Suh, W Y Kwon, S B Ko, K S Kim, A Xini, L Marca, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, A Beane, M C K T Thilakasiri, A P De Silva, T Stephens, C S Sigera, P Athapattu, S Jayasinghe, A Padeniya, R Haniffa, A Iglesias Santiago, V Chica Sáez, R de la Chica Ruiz-Ruano, A Sánchez González, N Kunze-Szikszay, S Wand, P Klapsing, A Wetz, T Heyne, K Schwerdtfeger, M Troeltzsch, M Bauer, M Quintel, O Moerer, D J Cook, W B Rutherford, D C Scales, N K Adhikari, B H Cuthbertson, T Suzuki, T Takei, K Fushimi, M Iwamoto, S Nakagawa, N Mendsaikhan, T Begzjav, G Lundeg, M W Dünser, D González Romero, J L Santana Cabrera, J D Martín Santana, Y Santana Padilla, H Rodríguez Pérez, R Lorenzo Torrent, R Kleinpell, I Chouris, V Radu, M Stougianni, A Lavrentieva, D Lagonidis, R D T Price, A Day, N Arora, M A Henderson, S Hickey, M I Almeida Costa, J P Carvalho, A A Gomes, P J Mergulhão, K K C Chan, H P Shum, W W Yan, B Maghsoudi, S H Tabei, M Masjedi, G Sabetian, H R Tabatabaei, A Akbarzadeh, S Saigal, A Pakhare, R Joshi, S K Pattnaik, B Ray, A F Rousseau, L Michel, M Bawin, E Cavalier, J Y Reginster, P Damas, O Bruyere, J C Zhou, H Cauwenberghs, A De Backer, H Neels, I Deblier, J Berghmans, D Himpe, J A Barea-Mendoza, I Prieto Portillo, M Valiente Fernández, R Garcia Gigorro, J L Perez Vela, H Marín Mateos, S Chacón Alves, G Morales Varas, A Rodriguez-Biendicho, E Renes Carreño, J C Montejo González, J S Yang, C H Chiang, W T Hung, W C Huang, C C Cheng, K C Lin, S C Lin, K R Chiou, S R Wann, K L Lin, P L Kang, G Y Mar, C P Liu, J C Zhou, Y J Choi, S Z Yoon, A Gordillo-Brenes, M D Fernandez-Zamora, L Perez-Borrero, M D Arias-Verdu, E Aguilar-Alonso, A Herruzo-Aviles, M Garcia-Delgado, R Hinojosa-Perez, E Curiel-Balsera, R Rivera-Fernandez, S P Gómez Lesmes, L E De la Cruz Rosario, A Ansotegui Hernández, A N García Herrera, E Regidor Sanz, M J Gómez Sánchez, J Barado Hualde, O Agudo Pascual, J P Tirapu León, J M Guergue Irazabal, A González Pérez, P Alvarez Fernández, L Lopéz Amor, G Muñiz Albaiceta, S P Gómez Lesmes, L E De la Cruz Rosario, A Ansotegui Hernández, E Regidor Sanz, M J Gómez Sánchez, S Aldunate Calvo, A N García Herrera, J Barado Hualde, O Agudo Pascual, J P Tirapu León, A Corona, C Ruffini, A Spazzadeschi, F Marrazzo, A Gandola, R Sciurti, C Savi, E Catena, M W Ke, C C Cheng, W C Huang, C H Chiang, W T Hung, K C Lin, S C Lin, S R Wann, K R Chiou, C J Tseng, P L Kang, G Y Mar, C P Liu, P Bertini, F De Sanctis, F Guarracino, P Bertini, R Baldassarri, F Guarracino, S H Buitinck, P H J van der Voort, J Oto, E Nakataki, Y Tsunano, M Izawa, N Tane, M Onodera, M Nishimura, S Ghosh, A Gupta, A De Gasperi, E Mazza, R Limuti, M Prosperi, N Bissenova, A Yergaliyeva, L Talan, G Yılmaz, G Güven, F Yoruk, N D Altıntas, D N Mukherjee, L K Agarwal, K Mandal, M Palomar, B Balsera, M Vallverdu, M Martinez, M Garcia, D Castellana, R Lopez, F Barcenilla, G E Kaminsky, R Carreño, A Escribá, M Fuentes, V Gálvez, R Del Olmo, B Nieto, C Vaquerizo, J Alvarez, M A De la Torre, E Torres, E Bogossian, S Aranha Nouer, D Ribeiro Salgado, S Carvalho Brugger, G Jiménez Jiménez, M Miralbés Torner, M Vallverdú Vidal, B Balsera Garrido, X Nuvials Casals, F Barcenilla Gaite, J Trujillano Cabello, M Palomar Martínez, M Doganci, S Izdes, S Guzeldag Besevli, A Alkan, B Kayaaslan, C Sánchez Ramírez, L Caipe Balcázar, M Cabrera Santana, M A Hernández Viera, S Hípola Escalada, C F Lübbe Vázquez, S M Marrero Penichet, F Artiles Campelo, M A De La Cal López, P Saavedra Santana, S Ruíz Santana, X Repessé, M Artiguenave, S Paktoris-Papine, F Espinasse, A Dinh, F El Sayed, C Charron, G Géri, A Vieillard-Baron, K Marmanidou, M Oikonomou, C Nouris, K Dimitroulakis, E Soilemezi, D Matamis, A Ferré, M Guillot, J L Teboul, D Lichtenstein, G Mézière, C Richard, X Monnet, T Pham, G Beduneau, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, S Prīdāne, O Sabeļņikovs, F Mojoli, A Orlando, I Bianchi, F Torriglia, S Bianzina, M Pozzi, G A Iotti, A Braschi, G Beduneau, T Pham, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, E Kondili, C Psarologakis, S Kokkini, V Amargianitakis, D Babalis, A Chytas, I Chouvarda, K Vaporidi, D Georgopoulos, O Trapp, A Kalenka, F Mojoli, A Orlando, I Bianchi, F Torriglia, S Bianzina, M Pozzi, G A Iotti, A Braschi, J A Benítez Lozano, P Carmona Sánchez, J E Barrueco Francioni, F Ruiz Ferrón, J M Serrano Simón, S Spadaro, D S Karbing, A Gioia, F Moro, F Dalla Corte, T Mauri, C A Volta, S E Rees, M V Petrova, R Mohan, A V Butrov, S D Beeharry, M V Vatsik, F I Sakieva, F Gobert, H Yonis, R Tapponnier, R Fernandez, M A Labaune, J F Burle, J Barbier, B Vincent, M Cleyet, J C Richard, C Guérin, C Righy Shinotsuka, J Creteur, F S Taccone, S Törnblom, S Nisula, S Vaara, M Poukkanen, S Andersson, V Pettilä, E Pesonen, Z Xie, X Liao, Y Kang, J Zhang, K Kubota, M Egi, S Mizobuchi, S Hegazy, A El-Keraie, E El Sayed, M Abd El Hamid, N J Rodrigues, M Pereira, I Godinho, J Gameiro, M Neves, J Gouveia, Z Costa E Silva, J A Lopes, J Mckinlay, M Kostalas, G Kooner, G Dudas, A Horton, C Kerr, N Karanjia, B Creagh-Brown, L Forni, A Yamazaki, M Sanz Ganuza, J A Martinez Molina, F Hidalgo Martinez, M T Chiquito Freile, N Garcia Fernandez, P Medrano Travieso, A Bandert, R Frithiof, M Lipcsey, D Smekal, P Schlaepfer, J D Durovray, V Plouhinec, C Chiappa, R Bellomo, A G Schneider, S Mitchell, J Durrant, H Street, E Dunthorne, J Shears, C Hernandez Caballero, R Hutchison, S Schwarze, S Ghabina, E Thompson, J R Prowle, C J Kirwan, C A Gonzalez, J L Pinto, V Orozco, J A Patiño, P K Garcia, K M Contreras, P Rodriguez, J E Echeverri
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27676247/a-novel-approach-to-proactive-primary-care-based-case-finding-and-multidisciplinary-management-of-falls-syncope-and-dizziness-in-a-one-stop-service-preliminary-results
#14
Steve W Parry, Harry Hill, Joanna Lawson, Nick Lawson, David Green, Heidi Trundle, Judith McNaught, Victoria Strassheim, Alma Caldwell, Richard Mayland, Phillip Earley, Peter McMeekin
National and international evidence and guidelines on falls prevention and management in community-dwelling elderly adults recommend that falls services should be multifactorial and their interventions multicomponent. The way that individuals are identified as having had or being at risk of falls in order to take advantage of such services is far less clear. A novel multidisciplinary, multifactorial falls, syncope, and dizziness service model was designed with enhanced case ascertainment through proactive, primary care-based screening (of individual case notes of individuals aged ≥60) for individual fall risk factors...
November 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27661864/point-prevalence-study-of-mobilization-practices-for-acute-respiratory-failure-patients-in-the-united-states
#15
Sarah Elizabeth Jolley, Marc Moss, Dale M Needham, Ellen Caldwell, Peter E Morris, Russell R Miller, Nancy Ringwood, Megan Anders, Karen K Koo, Stephanie E Gundel, Selina M Parry, Catherine L Hough
OBJECTIVE: Early mobility in mechanically ventilated patients is safe, feasible, and may improve functional outcomes. We sought to determine the prevalence and character of mobility for ICU patients with acute respiratory failure in U.S. ICUs. DESIGN: Two-day cross-sectional point prevalence study. SETTING: Forty-two ICUs across 17 Acute Respiratory Distress Syndrome Network hospitals. PATIENTS: Adult patients (≥ 18 yr old) with acute respiratory failure requiring mechanical ventilation...
February 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/27625317/scan_tcga-tools-for-integrated-epigenomic-and-transcriptomic-analysis-of-tumor-subgroups
#16
Aniruddha Chatterjee, Peter A Stockwell, Euan J Rodger, Matthew F Parry, Michael R Eccles
AIM: The Cancer Genome Atlas contains multiple levels of genomic data (mutation, gene expression, DNA methylation, copy number variation) for 33 cancer types for almost 11,000 patients. However, a dearth of appropriate software tools makes it difficult for bench scientists to use these data effectively. MATERIALS & METHODS: Here, we present a suite of flexible, fast and command line-based scripts that will allow retrieval and analysis of DNA methylation (tool: scan_tcga_methylation...
October 2016: Epigenomics
https://www.readbyqxmd.com/read/27625211/beyond-cdr-grafting-structure-guided-humanization-of-framework-and-cdr-regions-of-an-anti-myostatin-antibody
#17
James R Apgar, Michelle Mader, Rita Agostinelli, Susan Benard, Peter Bialek, Mark Johnson, Yijie Gao, Mark Krebs, Jane Owens, Kevin Parris, Michael St Andre, Kris Svenson, Carl Morris, Lioudmila Tchistiakova
Antibodies are an important class of biotherapeutics that offer specificity to their antigen, long half-life, effector function interaction and good manufacturability. The immunogenicity of non-human-derived antibodies, which can be a major limitation to development, has been partially overcome by humanization through complementarity-determining region (CDR) grafting onto human acceptor frameworks. The retention of foreign content in the CDR regions, however, is still a potential immunogenic liability. Here, we describe the humanization of an anti-myostatin antibody utilizing a 2-step process of traditional CDR-grafting onto a human acceptor framework, followed by a structure-guided approach to further reduce the murine content of CDR-grafted antibodies...
October 2016: MAbs
https://www.readbyqxmd.com/read/27468772/introduction-priority-setting-equitable-access-and-public-involvement-in-health-care
#18
Albert Weale, Katharina Kieslich, Peter Littlejohns, Aviva Tugendhaft, Emma Tumilty, Krisantha Weerasuriya, Jennifer A Whitty
Purpose - The purpose of this paper is to introduce the special issue on improving equitable access to health care through increased public and patient involvement (PPI) in prioritization decisions by discussing the conceptualization, scope and rationales of PPI in priority setting that inform the special issue. Design/methodology/approach - The paper employs a mixed-methods approach in that it provides a literature review and a conceptual discussion of the common themes emerging in the field of PPI and health priority setting...
August 15, 2016: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/27447437/situational-awareness-what-it-means-for-clinicians-its-recognition-and-importance-in-patient-safety
#19
REVIEW
B Green, D Parry, R S Oeppen, S Plint, T Dale, P A Brennan
A thorough understanding of the role of human factors in error in health care for improving patient safely is paramount. One area particularly crucial for optimising clinical performance is the recognising the importance of situational awareness. Loss of situation awareness can occur in many different settings, particularly during stressful and unexpected situations. Tunnel vision is a classic example where clinicians focus on one aspect of care, often to the detriment of overall patient management. Loss of situational awareness can result in serious compromise to patient safety if it is not recognised by either the individual or clinical team...
July 22, 2016: Oral Diseases
https://www.readbyqxmd.com/read/27367766/standardized-rehabilitation-and-hospital-length-of-stay-among-patients-with-acute-respiratory-failure-a-randomized-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Peter E Morris, Michael J Berry, D Clark Files, J Clifton Thompson, Jordan Hauser, Lori Flores, Sanjay Dhar, Elizabeth Chmelo, James Lovato, L Douglas Case, Rita N Bakhru, Aarti Sarwal, Selina M Parry, Pamela Campbell, Arthur Mote, Chris Winkelman, Robert D Hite, Barbara Nicklas, Arjun Chatterjee, Michael P Young
IMPORTANCE: Physical rehabilitation in the intensive care unit (ICU) may improve the outcomes of patients with acute respiratory failure. OBJECTIVE: To compare standardized rehabilitation therapy (SRT) to usual ICU care in acute respiratory failure. DESIGN, SETTING, AND PARTICIPANTS: Single-center, randomized clinical trial at Wake Forest Baptist Medical Center, North Carolina. Adult patients (mean age, 58 years; women, 55%) admitted to the ICU with acute respiratory failure requiring mechanical ventilation were randomized to SRT (n=150) or usual care (n=150) from October 2009 through May 2014 with 6-month follow-up...
June 28, 2016: JAMA: the Journal of the American Medical Association
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