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Sciatica

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https://www.readbyqxmd.com/read/28812185/reliability-of-standing-weight-bearing-0-25t-mr-imaging-findings-and-positional-changes-in-the-lumbar-spine
#1
Bjarke B Hansen, Philip Hansen, Anders F Christensen, Charlotte Trampedach, Zoreh Rasti, Henning Bliddal, Mikael Boesen
OBJECTIVE: To test the reliability and absolute agreement of common degenerative findings in standing positional magnetic resonance imaging (pMRI). METHODS AND MATERIALS: Low back pain patients with and without sciatica were consecutively enrolled to undergo a supine and standing pMRI. Three readers independently evaluated the standing pMRI for herniation, spinal stenosis, spondylolisthesis, HIZ lesions and facet joint effusion. The evaluation included a semi-quantitative grading of spinal stenosis, foraminal stenosis and spinal nerve root compression...
August 15, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28803493/health-related-quality-of-life-of-people-with-multimorbidity-at-a-community-based-interprofessional-student-assisted-clinic-implications-for-assessment-and-intervention
#2
Zephanie Tyack, Suzanne Kuys, Petrea Cornwell, Kerrie-Anne Frakes, Steven McPhail
Objective This study examined the relationship between the number of comorbidities and health-related quality of life (HRQoL) and between select physical conditions and HRQoL. Differences in HRQoL in comparison to a normative sample were also examined. Method A cross-sectional study among people with multimorbidity ( n = 401) attending a community-based, interdisciplinary health clinic was conducted. HRQoL was measured using the eight dimensions of the SF-36. Multiple linear regression and t-tests were used to analyse the data...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28779960/efficacy-and-safety-of-etanercept-in-the-treatment-of-sciatica-a-systematic-review-and-meta-analysis
#3
REVIEW
Shangfei Jing, Chenyuan Yang, Xiaofei Zhang, Shuzheng Wen, Yuankui Li
Etanercept might be promising to alleviate sciatica caused by lumbar disc herniation and spinal stenosis. However, the results remained controversial. We conducted a systematic review and meta-analysis to evaluate the efficacy of etanercept in patients with sciatica. PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) and Controlled clinical trials (CCT) assessing the efficacy of etanercept on sciatica caused by lumbar disc herniation and spinal stenosis were included...
August 2, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28762109/dual-lumbar-bronchogenic-and-arachnoid-cyst-presenting-with-sciatica-and-left-foot-drop
#4
Nicholas Candy, Adam Young, Abel Devadass, Andrew Dean, Jason McMillen, Rikin Trivedi
INTRODUCTION: Spinal bronchogenic cysts are rare findings, with only four cases of lumbar bronchogenic cysts reported in the literature. All of these bronchogenic cysts involved the conus medullaris. We present the first case of a lumbar bronchogenic cyst and arachnoid cyst arising from the cauda equina in a 68-year-old male. Uniquely, this bronchogenic cyst also contained components of an arachnoid cyst. METHODS: Magnetic resonance imaging (MRI) demonstrated a compressive cystic lesion at the level of the L3 vertebra splaying the cauda equina...
July 31, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28750940/lifestyle-risk-factors-increase-the-risk-of-hospitalization-for-sciatica-findings-of-four-prospective-cohort-studies
#5
Rahman Shiri, Ulla Euro, Markku Heliövaara, Mirja Hirvensalo, Kirsti Husgafvel-Pursiainen, Jaro Karppinen, Jouni Lahti, Ossi Rahkonen, Olli T Raitakari, Svetlana Solovieva, Yang Xiaolin, Eira Viikari-Juntura, Tea Lallukka
BACKGROUND: To assess the effects of lifestyle risk factors on the risk of hospitalization for sciatica and to determine whether overweight or obesity modifies the effect of leisure-time physical activity on hospitalization for sciatica. METHODS: We included four Finnish prospective cohort studies (Health 2000 Survey, Mobile Clinic Survey, Helsinki Health Study and Young Finns Study) consisting of 34,589 participants and 1259 hospitalizations for sciatica during 12 to 30 years follow-up...
July 24, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28746067/perturbing-nr2b-psd-95-interaction-relieves-neuropathic-pain-by-inactivating-camkii-creb-signaling
#6
Fangxia Xu, Xin Zhao, Lin Liu, Jia Song, Yingjun Zhu, Shuaishuai Chu, Xueming Shao, Xiuxiu Li, Zhengliang Ma, Xiaoping Gu
Neuropathic pain is characterized by central sensitization. The interaction between N-methyl-D-aspartate receptors (NMDARs) and postsynaptic density protein-95 (PSD-95) plays a major role in central sensitization. Here, we aimed to investigate the analgesic effect of disruption of the interaction between NMDAR and PSD-95. Chronic dorsal root ganglia compression model rats were used to mimic sciatica. Thermal hyperalgesia and mechanical allodynia were evaluated. The expression of spinal phospho-NR2B, PSD-95, calcium/calmodulin-dependent protein kinase II (CaMKII), and cAMP response element binding protein (CREB) was measured using western blotting...
September 6, 2017: Neuroreport
https://www.readbyqxmd.com/read/28745066/a-comparison-of-the-efficacy-and-tolerability-of-the-treatments-for-sciatica-a-network-meta-analysis
#7
Jian-Rong Guo, Xiao-Ju Jin, Hua-Chun Shen, Huan Wang, Xun Zhou, Xiao-Qian Liu, Na-Na Zhu
BACKGROUND: There remains a lack of a systematic summary of the efficacy and safety of various medicines for sciatica, and discrepancies among these exist. OBJECTIVE: The aim of this study is to comprehensively assess the efficacy of and tolerance to several medical options for the treatment of sciatica. METHODS: We performed a network meta-analysis and illustrated the results by the mean difference or odds ratio. The surface under the cumulative ranking curve (SUCRA) was used for indicating the preferable treatments...
July 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28741033/refractory-sciatica-caused-by%C3%A2-gluteal-varicosities
#8
Zheng Zhang, Xuebing Zhang, Chen Yang, Xiaoyu Wen
We report a case of sciatica that fulfilled the diagnostic criteria for inferior gluteal vein varicosities according to patient history and on magnetic resonance imaging. Since conservative treatment was ineffective, excision-ligation of the varicose vein was performed as recommended in the previous literature. However, pain was only slightly relieved and then aggravated. Reoperation involving wide release and resection of the piriformis outlet was performed. Pain resolved immediately thereafter. We suggest that this case of sciatica resulted from both piriformis entrapment and vein varicosities...
July 24, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28735122/ventral-lumbar-synovial-cyst-causing-cauda-equina-compression-case-report-and-literature-review
#9
Anan Shtaya, Ahmed-Ramadan Sadek, Mark Walker, Ali Nader-Sepahi
BACKGROUND: Juxtafacet spinal cysts are cystic synovial lesions that are often indistinguishable clinically or radiologically and require histopathology analysis to confirm the diagnosis. Lumbar synovial cysts usually arising from the synovium of the facet joints. They have been described posterolateral or rarely in the posterior midline. However, we describe the first synovial cyst ventral to the dural sac. CASE DESCRIPTION: We report a lumbar 3-4 lesion causing cauda equina compression in a 57-year-old man who presented with 3 months history of low back pain and bilateral sciatica, intermittent urinary incontinence and erectile dysfunction...
July 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28727705/activation-of-the-rage-stat3-pathway-in-the-dorsal-root-ganglion-contributes-to-the-persistent-pain-hypersensitivity-induced-by-lumbar-disc-herniation
#10
Xin-Sheng Zhang, Xiao Li, Hai-Jie Luo, Zhu-Xi Huang, Cui-Cui Liu, Qing Wan, Shu-Wei Xu, Shao-Ling Wu, Song-Jian Ke, Chao Ma
BACKGROUND: Clinically, chronic low back pain and sciatica associated with lumbar disc herniation (LDH) is a common musculoskeletal disorder. Due to the unawareness of detailed mechanisms, it is difficult to get an effective therapy. OBJECTIVE: The aim of the present study was to identify the role of the RAGE/STAT3 pathway in the dorsal root ganglion (DRG) on the formation and development of persistent pain hypersensitivity induced by LDH. STUDY DESIGN: Controlled animal study...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28720992/ganglion-cyst-of-the-hip-mimicking-lumbar-disk-herniation-a-case-report
#11
Devendra Lakhotia, Kumar Prashant, Won Yong Shon
Sciatic nerve compression due to a ganglion cyst around the posterior aspect of the hip joint is not commonly described in literature. We report a rare case of a 63-year-old man with a ganglion cyst around his hip joint, who presented with symptoms of sciatica. After excision of the cyst, the patient was symptom free. A high index of clinical doubt and detailed clinical examination is required for non-palpable cystic lesions in close proximity to the sciatic nerve in patients presenting with symptoms of sciatica and in patients with concomitant of lumbar disk herniation...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28720991/transforaminal-epidural-etanercept-for-the-treatment-of-prolapsed-lumbar-intervertebral-disc-induced-sciatica
#12
Ashish Dagar, Ramesh Kumar, Abhishek Kashyap, Vinay Prabhat, Hitesh Lal, Lalit Kumar
STUDY DESIGN: Hospital based prospective study. OBJECTIVE: To study clinical response of transforaminal epidural Etanercept for lumbar prolapsed intervertebral disc induced sciatica. METHOD: Patients presenting to O.P.D and Emergency services of our hospital were screened for inclusion and exclusion criteria & suitable candidates were enrolled in study. Patients received 2 transforaminal epidural injections of Etanercept 2 mg, 2 weeks apart, and were assessed for efficacy at 2 week, 1 month and 3 months after the second injection...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28716031/a-rare-case-of-intradural-and-extramedullary-epidermoid-cyst-after-repetitive-epidural-anesthesia-case-report-and-review-of-the-literature
#13
Haruki Funao, Norihiro Isogai, Kenshi Daimon, Yuichiro Mima, Hitoshi Sugiura, Takahiro Koyanagi, Masaya Nakamura, Morio Matsumoto, Ken Ishii
BACKGROUND: Spinal epidermoid cysts are benign tumors, which are rarely seen as an intradural extramedullary spinal cord tumor in the conus medullaris region. Acquired spinal epidermoid cysts are mostly caused by iatrogenic procedures, such as lumbar puncture, and the majority of acquired spinal epidermoid cysts have been reported below the L1 level, because lumbar puncture is usually performed around the iliac crest. Here, we report an extremely rare case of an epidermoid cyst that occurred as an intradural and extramedullary spinal cord tumor attached to the conus medullaris after repetitive epidural anesthesia...
July 17, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28715826/in-moderate-to-severe-sciatica-pregabalin-did-not-reduce-leg-pain-intensity-or-improve-quality-of-life
#14
Eyad Al-Hihi, Robert G Badgett
No abstract text is available yet for this article.
July 18, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28705700/incidental-primary-intradural-carcinoid-tumor-in-a-patient-with-lumbar-radiculopathy
#15
Stavros Koustais, Philip O'Halloran, Alfrazdaq Hassan, Francesca Brett, Steven Young
BACKGROUND: Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, as well as primary skeletal or extradural disease resulting in compressive myelo-radiculopathy. There are two previously reported cases of primary intradural extramedullary carcinoid tumor, presenting with compressive symptoms. We report the first case of primary incidental intradural extramedullary carcinoid tumor...
July 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28679342/percutaneous-laser-disc-decompression-versus-microdiscectomy-for-sciatica-cost-utility-analysis-alongside-a-randomized-controlled-trial
#16
M Elske van den Akker-van Marle, Patrick A Brouwer, Ronald Brand, Bart Koes, Wilbert B van den Hout, Mark A van Buchem, Wilco C Peul
Background Percutaneous laser disc decompression (PLDD) for patients with lumbar disc herniation is believed to be cheaper than surgery. However, cost-effectiveness has never been studied. Materials and Methods A cost utility analysis was performed alongside a randomized controlled trial comparing PLDD and conventional surgery. Patients reported their quality of life using the EuroQol five dimensions questionnaire (EQ-5D), 36-item short form health survey (SF-36 and derived SF-6D) and a visual analogue scale (VAS)...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28676098/noncontiguous-multi-tiered-spinal-tuberculosis-associated-with-sternal-localization-a-case-report
#17
Mariam Erraoui, Bouchra Amine, Latifa Tahiri, Imane El Binoune, Jihane Bahha, Najia Hajjaj-Hassouni
BACKGROUND: Tuberculous spondylodiscitis is a frequent localization of tuberculosis. Multi-tiered involvement and an association with sternal localization are rare. CASE PRESENTATION: We report a case of multi-tiered tuberculous spondylodiscitis with sternal localization in an immunocompetent 41-year-old Arab woman who had inflammatory bilateral sciatica L5 and S1 and a history of low back pain caused by a trauma. Radiography, computed tomography, and a vertebral biopsy were useful for diagnosis...
July 5, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28658038/immediate-versus-delayed-surgical-treatment-of-lumbar-disc-herniation-for-acute-motor-deficits-the-impact-of-surgical-timing-on-functional-outcome
#18
Ondra Petr, Bernhard Glodny, Konstantin Brawanski, Johannes Kerschbaumer, Christian Freyschlag, Daniel Pinggera, Rafael Rehwald, Sebastian Hartmann, Martin Ortler, Claudius Thomé
STUDY DESIGN: A retrospective cohort study. OBJECTIVE: The aim of the study was to assess the impact of time to surgery in patients with MDs on their functional outcome. The current single-center study presents results of emergency surgery for LDH in a group of patients with acute paresis in a "real-world" setting. SUMMARY OF BACKROUND DATA: Motor deficits (MDs) are a frequent symptom of lumbar disc herniation (LDH). While surgery within 48 hours has been recommended for cauda-equina syndrome, the best timing of surgery for acute MDs continues to be debated...
June 27, 2017: Spine
https://www.readbyqxmd.com/read/28652808/persistent-cauda-equina-syndrome-after-caudal-epidural-injection-under-severe-spinal-stenosis-a-case-report
#19
Young Tak Seo, Hyun Ho Kong, Goo Joo Lee, Heui Je Bang
Caudal epidural injection (CEI) is one of the most common treatments for low-back pain with sciatica. CEI rarely leads to neurologic complications. We report a case of persistent cauda equina syndrome after CEI. A 44-year-old male patient with severe L4 and L5 spinal ste-nosis underwent CEI for low-back pain and sciatica. The CEI solution consisted of bupivacaine, hyaluronidase, triamcinolone acetonide, and normal saline. He experienced motor weakness and sensory loss in both lower extremities and neurogenic bladder for more than 1 year after the procedure...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28632645/management-of-symptomatic-lumbar-disk-herniation-an-international-perspective
#20
Pravesh S Gadjradj, Mark P Arts, Maurits W van Tulder, Wim J R Rietdijk, Wilco C Peul, Biswadjiet S Harhangi
STUDY DESIGN: A questionnaire survey. OBJECTIVE: To evaluate the current practice patterns of surgeons regarding both the surgical and nonsurgical management of lumbar disk herniation (LDH) worldwide and to compare this with the current literature. SUMMARY OF BACKGROUND DATA: Sciatica is a common diagnosis in the general population. Sciatica is most frequently caused by LDH. Multiple surgical techniques and treatment modalities are available to treat LDH, albeit some with small effect sizes or without compelling evidence...
June 19, 2017: Spine
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