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https://www.readbyqxmd.com/read/29151051/subclinical-propionibacterium-acnes-infection-estimation-in-the-intervertebral-disc-spine-id-protocol-for-a-prospective-cohort
#1
Nelson Astur, Delio E Martins, Marcelo Wajchenberg, Mario Ferretti, Fernando G Menezes, Andre M Doi, Laercio A Rosemberg, Durval C B Santos, Alexandre S Iutaka, Luciano M R Rodrigues, Marines D V Martino, Jorge R Pagura, Eduardo N Kihara Filho, Mario Lenza
INTRODUCTION: Low back pain and vertebral endplate abnormalities are common conditions within the population. Subclinical infection caused by indolent pathogens can potentially lead to these findings, with differentiation between them notably challenging from a clinical perspective. Progressive infection of the intervertebral disc has been extensively associated with increasing low back pain, with Propionibacterium acnes specifically implicated with in relation to sciatica. The main purpose of this study is to identify if the presence of an infective pathogen within the intervertebral disc is primary or is a result of intraoperative contamination, and whether this correlates to low back pain...
November 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/29147155/endovascular-stent-graft-repair-of-a-persistent-sciatic-artery-aneurysm
#2
Hayato Fukuda, Seiji Onitsuka, Shohei Yoshida, Yuichiro Hirata, Shinichi Hiromatsu, Hiroyuki Tanaka
Persistent sciatic artery (PSA) is a rare anomaly that may cause various symptoms, such as aneurysm, rupture, thromboembolism, and sciatica. Direct surgery can be performed to treat PSA aneurysm (PSAA), but is associated with complications; e.g., anatomical problems such as sciatic nerve injury. Herein we report a case of a 74-year-old woman with acute limb ischemia that developed from a distal embolism caused by a thrombus in the left PSAA; favorable results were obtained for her by treatment with a stent-graft after rapid anticoagulation therapy for limb salvage...
September 25, 2017: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/29138591/anatomical-etiology-of-pseudo-sciatica-from-superior-cluneal-nerve-entrapment-a-laboratory-investigation
#3
Tomoyuki Konno, Yoichi Aota, Hiroshi Kuniya, Tomoyuki Saito, Ning Qu, Shogo Hayashi, Shinichi Kawata, Masahiro Itoh
Objective: The superior cluneal nerve (SCN) may become entrapped where it pierces the thoracolumbar fascia over the iliac crest; this can cause low back pain (LBP) and referred pain radiating into the posterior thigh, calf, and occasionally the foot, producing the condition known as "pseudo-sciatica." Because the SCN was thought to be a cutaneous branch of the lumbar dorsal rami, originating from the dorsal roots of L1-L3, previous anatomical studies failed to explain why SCN causes "pseudo-sciatica"...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29131732/yoga-and-healthcare-in-the-united-kingdom
#4
Heather Mason, Nicole Schnackenberg, Robin Monro
The emergence of yoga therapy in the United Kingdom began about 45 years ago with the emergence of yoga therapy organizations that offered both treatment and training. The integration of yoga into the National Health Service (NHS) is gradually happening Because: (a) yoga research supports its efficacy as a cost-effective, preventive and complementary treatment for a host of non-communicable diseases; and (b) the escalating economic burden of long-term conditions is overwhelming the NHS. The NHS is actively developing 'sustainability and transformation plans' that include yoga...
November 2017: International Journal of Yoga Therapy
https://www.readbyqxmd.com/read/29097408/-18-f-fdg-pet-mri-in-chronic-sciatica-early-results-revealing-spinal-and-non-spinal-abnormalities
#5
Peter Cipriano, Daehyun Yoon, Harsh Gandhi, Dawn Holley, Dushyant Thakur, Ma Ith, Brian Hargreaves, David Kennedy, Matthew Smuck, Ivan Cheng, Sandip Biswal
Chronic sciatica is a major cause of disability worldwide, but accurate diagnosis of the offending pathology remains challenging. In this report, the feasibility of a fluorodeoxyglucose ((18)F-FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) approach for improved diagnosis of chronic sciatica is presented. Methods:(18)F-FDG PET/MRI was performed on 9 chronic sciatica patients and 5 healthy volunteers. Region-of-interest analysis using maximum standardized uptake values (SUVmax) was performed, and (18)F-FDG uptake in lesions was compared with the corresponding areas in healthy controls...
November 2, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29086028/association-between-chronic-inflammation-and-latent-infection-of-propionibacterium-acnes-in-non-pyogenic-degenerated-intervertebral-discs-a-pilot-study
#6
Ye Yuan, Yong Chen, Zezhu Zhou, Yucheng Jiao, Changwei Li, Yuehuan Zheng, Yazhou Lin, Jiaqi Xiao, Zhe Chen, Peng Cao
PURPOSE: Propionibacterium acnes may be considered a new pathogeny for disc degeneration, but its pathological role has remained unclear. This study was designed to determine whether the latent infection of P. acnes was associated with chronic inflammation in degenerated intervertebral discs via quantification of the levels of a series of cytokines and neutrophils. METHODS: Here, 76 degenerated intervertebral discs were harvested from patients with lower back pain and/or sciatica...
October 31, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29084706/review-ricinus-cmmunis-ethnomedicinal-uses-and-pharmacological-activities
#7
Sarfaraz Khan Marwat, Fazalur Rehman, Ejaz Ahmad Khan, Mohammad Safdar Baloch, Muhammad Sadiq, Imdad Ullah, Sadaf Javaria, Salma Shaheen
Ricinus cmmunis L. (Castor oil plant) is an important medicinal plant belonging to family Euphorbiaceae. Its phytochemistry, biological and pharmacological activities, and ethnomedicinal uses have been reviewed in the present study. The reported chemical constituents showed the presence of flavonoids, phenolic compounds, fatty acids, amino acids, terpenoids, phytosterol etc. The compounds have been reported to exhibit anticonceptive, antidiabetic, antifertility, anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, insecticidal and wound-healing activities...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29074423/percutaneous-endoscopic-lumbar-reoperation-for-recurrent-sciatica-symptoms-a-retrospective-analysis-of-outcomes-and-prognostic-factors-in-94-patients
#8
Junlong Wu, Chao Zhang, Kang Lu, Changqing Li, Yue Zhou
BACKGROUND: Recurrent sciatica symptoms after the prior surgical intervention is a relatively common and troublesome clinical problem. Percutaneous endoscopic lumbar decompression has been proved an effective method for recurrent lumbar disc herniation. However, the prognostic factors and outcomes of percutaneous endoscopic lumbar reoperation (PELR) for recurrent sciatica symptoms were still unknown. The purpose of this study was to evaluate the outcomes and prognostic factors of patients who underwent PELR for recurrent sciatica symptoms...
October 23, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29069932/lumbar-intravertebral-disc-herniation-secondary-to-idiopathic-calcific-discitis
#9
Ahmed-Ramadan Sadek, Christopher Dare, Stephen McGillion, Ali Nader-Sepahi, Vasileios Skiadas
Calcific discitis is a well recognized entity in the paediatric population but more recently has been increasingly reported in adults. It typically involves the lower thoracic vertebrae and is of unknown aetiology. Herniation of the calcified fragment is rare but typically occurs out through the annulus fibrosus into the canal space. Herein we describe the first reported case of calcific discitis involving the lumbar vertebrae with subsequent herniation of the calcified disc into and through the anterior aspect of the L5 vertebra...
October 26, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29063827/subcutaneous-injection-of-adalimumab-trial-compared-with-control-sciatic-a-randomised-controlled-trial-of-adalimumab-injection-compared-with-placebo-for-patients-receiving-physiotherapy-treatment-for-sciatica
#10
Nefyn H Williams, Alison Jenkins, Nia Goulden, Zoe Hoare, Dyfrig A Hughes, Eifiona Wood, Nadine E Foster, David A Walsh, Dawn Carnes, Valerie Sparkes, Elaine M Hay, John Isaacs, Kika Konstantinou, Dylan Morrissey, Jaro Karppinen, Stephane Genevay, Clare Wilkinson
BACKGROUND: Biological treatments such as adalimumab (Humira(®); AbbVie Ltd, Maidenhead, UK) are antibodies targeting tumour necrosis factor alpha, released from ruptured intervertebral discs, which might be useful in sciatica. Recent systematic reviews concluded that they might be effective, but that a definitive randomised controlled trial was needed. Usual care in the NHS typically includes a physiotherapy intervention. OBJECTIVES: To test whether or not injections of adalimumab plus physiotherapy are more clinically effective and cost-effective than injections of saline plus physiotherapy for patients with sciatica...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29051870/an-unusual-case-report-of-bertolotti-s-syndrome-extraforaminal-stenosis-and-l5-unilateral-root-compression-castellvi-type-iii-an-lstv
#11
Stylianos Kapetanakis, Constantinos Chaniotakis, Constantinos Paraskevopoulos, Pavlos Pavlidis
INTRODUCTION: Castellvi Type III lumbosacral transitional vertebrae (LSTV) is an unusual case of Bertolotti's syndrome (BS) due to extraforaminal stenosis, especially manifesting in elderly patients. CASE REPORT: We report a case of BS in a 62 years old Greek female. The signs of the clinical examination are low back pain, sciatica, hypoesthesia, and pain to the contribution of L5 nerve. Imaging techniques revealed an LSTV Type III a (complete sacralization between LSTV and sacrum)...
May 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29025735/which-pain-medications-are-effective-for-sciatica-radicular-leg-pain
#12
Rafael Zambelli Pinto, Annemieke J H Verwoerd, Bart W Koes
No abstract text is available yet for this article.
October 12, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29023556/lumbar-spinal-canal-mri-diameter-is-smaller-in-herniated-disc-cauda-equina-syndrome-patients
#13
Nina S Korse, Mark C Kruit, Wilco C Peul, Carmen L A Vleggeert-Lankamp
INTRODUCTION: Correlation between magnetic resonance imaging (MRI) and clinical features in cauda equina syndrome (CES) is unknown; nor is known whether there are differences in MRI spinal canal size between lumbar herniated disc patients with CES versus lumbar herniated discs patients without CES, operated for sciatica. The aims of this study are 1) evaluating the association of MRI features with clinical presentation and outcome of CES and 2) comparing lumbar spinal canal diameters of lumbar herniated disc patients with CES versus lumbar herniated disc patients without CES, operated because of sciatica...
2017: PloS One
https://www.readbyqxmd.com/read/29017307/incarceration-of-spinal-nerve-root-through-incidental-durotomy-as-a-cause-of-sciatica
#14
Young-Jin Kim
Incidental durotomies are a frequent complication during spinal surgery. Cerebrospinal fluid (CSF) leakage from a dural tear may be visually apparent intraoperatively, but occasionally, a tear may not be recognized during the procedure. We report our experience in 2 cases of postoperative incarceration of nerve root as a cause of sciatica, without CSF leakage intraoperatively. When durotomy attributable to surgical manipulation does occur, intraoperative identification is mandated. If a patient develops unexplainable postoperative pain and neurological deficits after lumbar discectomy, incarceration of nerve root should be considered in the differential diagnosis...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28948841/comment-a-comparison-of-the-efficacy-and-tolerability-of-the-treatments-for-sciatica-a-network-meta-analysis
#15
Matthew K Bagg, James H McAuley
No abstract text is available yet for this article.
September 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28948840/reply-a-comparison-of-the-efficacy-and-tolerability-of-the-treatments-for-sciatica-a-network-meta-analysis
#16
Jian-Rong Guo, Xiao-Ju Jin, Hua-Chun Shen, Huan Wang, Xun Zhou, Xiao-Qian Liu, Na-Na Zhu
No abstract text is available yet for this article.
September 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28946543/a-misdiagnosed-case-of-osteoid-osteoma-of-l5
#17
Xiaoyong Sheng, Guangyong Cai, Xingjun Gong, Zouying Yao, Ye Zhu
Clinically, it is difficult to differentiate osteoid osteoma, more than 50% of which occur in the fibia or tibia, from other diseases, i.e. spinal degenerative diseases, inflammatory and noninflammatory arthritis. In this case report, we presented an unusual case of lumbar osteoid osteoma in a 38-year-old male, who experienced low back pain and sciatica as initial symptoms. The patient was initially misdiagnosed as lumbar disc herniation for more than 10 years. With the usage of computed tomography (CT) and magnetic resonance imaging (MRI), the patient was finally diagnosed as osteoid osteoma in L5...
September 8, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28946515/effects-of-biofeedback-versus-switch-triggered-functional-electrical-stimulation-on-sciatica-related-foot-drop
#18
Dragos Petrica Sardaru, Daniela Matei, Dan Zaharia-Kezdi, Liviu Pendefunda
BACKGROUND: Sciatica-related Foot Drop is a peripheral nervous condition that produces a loss of power in the ankle dorsiflexion muscles. Functional electrical stimulation is a modality of electrical stimulation that produces muscle contraction in a functional movement of the limb. This technique was utilized with positive effects in central nervous afflictions but it is not known whether or not it has any influence in motor recovery following peripheral nervous system problems. This study aims to clarify the effects of functional electrical stimulation on foot drop caused by peripheral nerve compression resulting from lumbar disc herniation...
September 8, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28934536/glomus-tumor-of-the-sciatic-nerve-an-extraspinal-cause-of-sciatica
#19
Basilia Onyinyechukwu Nwankwo, Robert M Henshaw, Dhruv Kumar
Glomus tumors are small, benign tumors that arise from glomus bodies, structures found normally within the dermis that assist in temperature regulation via their vasoconstrictive response to sympathetic stimuli. Glomus tumors are found typically in the hand and are classically a cause of focal pain and temperature sensitivity. They often present as a small blue lesion seen under the nail bed of a finger or a toe and cause point tenderness. Glomus tumors of peripheral nerves are exceedingly rare and can lead to disability akin to compressive neuropathy when present...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28933238/staged-decrease-of-physical-ability-on-the-locomotive-syndrome-risk-test-is-related-to-neuropathic-pain-nociceptive-pain-shoulder-complaints-and-quality-of-life-in-middle-aged-and-elderly-people-the-utility-of-the-locomotive-syndrome-risk-test
#20
Shiro Imagama, Yukiharu Hasegawa, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Mikito Tsushima, Yoshihiro Nishida, Naoki Ishiguro
OBJECTIVES: A locomotive syndrome (LS) risk test for evaluation of physical ability is recently proposed. The objective of this study is to evaluate the utility of this test by examining physical ability, neuropathic pain, nociceptive pain, shoulder complaints, and quality of life (QOL). METHODS: A prospective cohort study was conducted in 523 subjects (240 males, 283 females; mean age: 63.3 years) at a health checkup. Data collected using visual analog scales (VAS) for shoulder pain, low back pain, sciatica, and knee pain, neuropathic pain, shoulder complaint, body mass index (BMI), osteoporosis, and SF-36 were compared among three LS risk stages...
November 2017: Modern Rheumatology
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