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https://www.readbyqxmd.com/read/28228138/current-management-practices-for-patients-presenting-with-low-back-pain-to-a-large-emergency-department-in-canada
#1
Matthew L Nunn, Jill A Hayden, Kirk Magee
BACKGROUND: Low back pain (LBP) is one of the leading causes of disability. Presentations to the emergency department (ED) are common and consume significant healthcare resources. However, treatment of patients with LBP is variable and highly physician dependent. Our study objective was to describe the demographic and clinical characteristics of patients presenting to the ED with LBP, the diagnostic strategies employed by ED physicians, and the subsequent management. METHODS: We conducted a retrospective study using clinical and electronic health data at the Queen Elizabeth II Health Science Center's Charles V...
February 23, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28223688/sequence-variant-at-8q24-21-associates-with-sciatica-caused-by-lumbar-disc-herniation
#2
Gyda Bjornsdottir, Stefania Benonisdottir, Gardar Sveinbjornsson, Unnur Styrkarsdottir, Gudmar Thorleifsson, G Bragi Walters, Aron Bjornsson, Ingvar H Olafsson, Elfar Ulfarsson, Arnor Vikingsson, Ragnheidur Hansdottir, Karl O Karlsson, Thorunn Rafnar, Ingileif Jonsdottir, Michael L Frigge, Augustine Kong, Asmundur Oddsson, Gisli Masson, Olafur T Magnusson, Tomas Gudbjartsson, Hreinn Stefansson, Patrick Sulem, Daniel Gudbjartsson, Unnur Thorsteinsdottir, Thorgeir E Thorgeirsson, Kari Stefansson
Lumbar disc herniation (LDH) is common and often debilitating. Microdiscectomy of herniated lumbar discs (LDHsurg) is performed on the most severe cases to resolve the resulting sciatica. Here we perform a genome-wide association study on 4,748 LDHsurg cases and 282,590 population controls and discover 37 highly correlated markers associating with LDHsurg at 8q24.21 (between CCDC26 and GSDMC), represented by rs6651255[C] (OR=0.81; P=5.6 × 10(-12)) with a stronger effect among younger patients than older. As rs6651255[C] also associates with height, we performed a Mendelian randomization analysis using height polygenic risk scores as instruments to estimate the effect of height on LDHsurg risk, and found that the marker's association with LDHsurg is much greater than predicted by its effect on height...
February 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/28216749/percutaneous-endoscopic-lumbar-discectomy-results-of-first-100-cases
#3
Kanthila Mahesha
BACKGROUND: Lumbar disc herniation is a major cause of back pain and sciatica. The surgical management of lumbar disc prolapse has evolved from exploratory laminectomy to percutaneous endoscopic discectomy. Percutaneous endoscopic discectomy is the least invasive procedure for lumbar disc prolapse. The aim of this study was to analyze the clinical outcome, quality of life, neurologic function, and complications. MATERIALS AND METHODS: One hundred patients with lumbar disc prolapse who were treated with percutaneous endoscopic discectomy from May 2012 to January 2014 were included in this retrospective study...
January 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28202486/granulocytic-sarcoma-a-rare-cause-of-sciatica
#4
Epaminondas Markos Valsamis, Thomas Edward Glover
We describe a case report of a man aged 56 years with a 4-month history of right-sided sciatica-type pain with subclinical disc prolapse evident on MRI. Worsening pain together with the appearance of a tender mass in his right buttock prompted further imaging, which demonstrated an infiltrative mass engulfing the lumbosacral plexus. This was later shown to be a granulocytic sarcoma on biopsy. Intervertebral disc herniation can be an incidental finding and is not always the cause of sciatica.
February 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28181641/risk-factors-for-low-back-pain-and-sciatica-in-elderly-men-the-mros-sweden-study
#5
Mehrsa Kherad, Björn E Rosengren, Ralph Hasserius, Jan-Åke Nilsson, Inga Redlund-Johnell, Claes Ohlsson, Dan Mellström, Mattiaz Lorentzon, Östen Ljunggren, Magnus K Karlsson
No abstract text is available yet for this article.
January 8, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28169960/non-steroidal-anti-inflammatory-drugs-for-sciatica-an-updated-cochrane-review
#6
Eva Rasmussen-Barr, Ulrike Held, Wilhelmus Ja Grooten, Pepijn Ddm Roelofs, Bart W Koes, Maurits W van Tulder, Maria M Wertli
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To determine the efficacy of Nonsteroidal anti-inflammatory drugs (NSAIDs) on pain reduction, overall improvement, and reported adverse effects in people with sciatica. SUMMARY OF BACKGROUND DATA: NSAIDs are one of the most frequently prescribed drugs for sciatica. METHODS: We updated a 2008 Cochrane Review through June 2015. Randomized controlled trials that compared NSAIDs to placebo, to other NSAIDs, or to other medication were included...
February 6, 2017: Spine
https://www.readbyqxmd.com/read/28160759/five-herbs-plus-thiamine-reduce-pain-and-improve-functional-mobility-in-patients-with-pain-a-pilot-study
#7
Robert Hedaya
: Context • Five herbs-Urtica dioica (stinging nettle), Boswellia serrata, Equisetum arvense, Allium sativum, and Apium graveolens-have been demonstrated to have activity at several anti-inflammatory pathways and have analgesic properties that are effective in treating chronic musculoskeletal pain. Objectives • The study intended to evaluate the clinical efficacy of a proprietary blend of U dioica, B serrata, E arvense, A sativum, A graveolens, and thiamine (vitamin B1), or "the blend," in the treatment of chronic musculoskeletal pain...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28146015/reoperation-for-recurrent-intervertebral-disc-herniation-in-the-spine-patient-outcomes-research-trial-analysis-of-rate-risk-factors-and-outcome
#8
Robert W Abdu, William A Abdu, Adam M Pearson, Wenyan Zhao, Jon D Lurie, James N Weinstein
STUDY DESIGN: This study was a post-hoc subgroup analysis of prospectively collected data in the Spine Patient Outcomes Research Trial (SPORT). OBJECTIVE: Determine the risk factors for and to compare the outcomes of patients undergoing revision disc excision surgery in SPORT. SUMMARY OF BACKGROUND DATA: Risk factors for reherniation and outcomes after revision surgery have not been well-studied. This information is critical for proper patient counseling and decision making...
January 31, 2017: Spine
https://www.readbyqxmd.com/read/28129548/a-preliminary-randomised-control-trial-of-the-effects-of-dru-yoga-on-psychological-well-being-in-northern-irish-first-time-mothers
#9
Deirdre Timlin, Ellen Elizabeth Anne Simpson
BACKGROUND: the transition to motherhood can be stressful, especially for first time mothers. Recent research has shown that yoga can be effective for enhancing psychological well-being. OBJECTIVES: the purpose of this study was to establish if a postpartum Dru yoga intervention improves psychological well-being in first time mothers. DESIGN: a randomised controlled study was conducted. SETTING AND PARTICIPANTS: first time mothers were recruited from a Sure Start Community Centre and included in the study if they had a baby aged between 6 weeks to one-year-old...
January 13, 2017: Midwifery
https://www.readbyqxmd.com/read/28119770/lumbar-herniated-disc-spontaneous-regression
#10
Idiris Altun, Kasım Zafer Yüksel
BACKGROUND: Low back pain is a frequent condition that results in substantial disability and causes admission of patients to neurosurgery clinics. To evaluate and present the therapeutic outcomes in lumbar disc hernia (LDH) patients treated by means of a conservative approach, consisting of bed rest and medical therapy. METHODS: This retrospective cohort was carried out in the neurosurgery departments of hospitals in Kahramanmaraş city and 23 patients diagnosed with LDH at the levels of L3-L4, L4-L5 or L5-S1 were enrolled...
January 2017: Korean Journal of Pain
https://www.readbyqxmd.com/read/28115269/stretching-of-roots-contributes-to-the-pathophysiology-of-radiculopathies
#11
Jean-Marie Berthelot, Jean-Denis Laredo, Christelle Darrieutort-Laffite, Yves Maugars
PURPOSE: To perform a synthesis of articles addressing the role of stretching on roots in the pathophysiology of radiculopathy. METHODS: Review of relevant articles on this topic available in the PubMed database. RESULTS: An intraoperative microscopy study of patients with sciatica showed that in all patients the hernia was adherent to the dura mater of nerve roots. During the SLR (Lasègue's) test, the limitation of nerve root movement occurs by periradicular adhesive tissue, and temporary ischemic changes in the nerve root induced by the root stretching cause transient conduction disturbances...
January 20, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28102451/cauda-equina-syndrome-presentation-outcome-and-predictors-with-focus-on-micturition-defecation-and-sexual-dysfunction
#12
N S Korse, J A Pijpers, E van Zwet, H W Elzevier, C L A Vleggeert-Lankamp
BACKGROUND: Even though micturition, defecation, and sexual function are substantially affected in cauda equina syndrome (CES), data on outcome are scarce. METHODS: Medical files of patients operated on lumbar herniated disc were screened for CES and retrospectively analyzed for baseline characteristics, outcome of micturition, defecation, and sexual function and possible predictors. RESULTS: Seventy-five CES patients (52% men) were included with a mean age of 44 years...
January 19, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28091818/lumbar-microdiscectomy-for-sciatica-in-adolescents-a-multicentre-observational-registry-based-study
#13
Sasha Gulati, Mattis A Madsbu, Tore K Solberg, Andreas Sørlie, Charalampis Giannadakis, Marius K Skram, Øystein P Nygaard, Asgeir S Jakola
BACKGROUND: Lumbar disc herniation (LDH) is rare in the adolescent population. Factors predisposing to LDH in adolescents differ from adults with more cases being related to trauma or structural malformations. Further, there are limited data on patient-reported outcomes after lumbar microdiscectomy in adolescents. Our aim was to compare clinical outcomes at 1 year following single-level lumbar microdiscectomy in adolescents (13-19 years old) compared to younger adults (20-50 years old) with LDH...
March 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28065875/comparing-quality-of-life-in-cervical-spondylotic-myelopathy-with-other-chronic-debilitating-diseases-using-the-sf-36-survey
#14
Taemin Oh, Renaud Lafage, Virginie Lafage, Themistocles Protopsaltis, Vincent Challier, Christopher Shaffrey, Han Jo Kim, Paul Arnold, Jens Chapman, Frank Schwab, Eric Massicotte, Tim Yoon, Shay Bess, Michael Fehlings, Justin Smith, Christopher Ames
BACKGROUND: Although cervical spondylotic myelopathy (CSM) can be devastating, its relative impact on general health remains unclear. Patient responses to the SF-36 PCS/MCS were compared between CSM and other diseases to evaluate their respective impacts on quality of life. OBJECTIVE: Compare SF-36 PCS/MCS scores in CSM to population and disease-specific norms. METHODS: Retrospective analysis of a prospective, multi-center AOSpine North American CSM Study database...
January 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28062522/low-back-pain-and-sciatica-summary-of-nice-guidance
#15
Ian A Bernstein, Qudsia Malik, Serena Carville, Stephen Ward
No abstract text is available yet for this article.
January 6, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28033733/isolation-crystal-structure-determination-and-cholinesterase-inhibitory-potential-of-isotalatizidine-hydrate-from-delphinium-denudatum
#16
Hanif Ahmad, Shujaat Ahmad, Ezzat Khan, Adnan Shahzad, Mumtaz Ali, Muhammad Nawaz Tahir, Farzana Shaheen, Manzoor Ahmad
CONTEXT: Delphinium denudatum Wall (Ranunculaceae) is a rich source of diterpenoid alkaloids and is widely used for the treatment of various neurological disorders such as epilepsy, sciatica and Alzheimer's disease. OBJECTIVE: The present study describes crystal structure determination and cholinesterase inhibitory potential of isotalatazidine hydrate isolated from the aerial part of Delphinium denudatum. MATERIALS AND METHODS: Phytochemical investigation of Delphinium denudatum resulted in the isolation of isotalatazidine hydrate in crystalline form...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28028573/diffusion-tensor-imaging-and-tractography-of-the-sciatic-nerve-assessment-of-fractional-anisotropy-and-apparent-diffusion-coefficient-values-relative-to-the-piriformis-muscle-a-preliminary-study
#17
Keizo Wada, Takuya Hashimoto, Ryo Miyagi, Toshinori Sakai, Koichi Sairyo
OBJECTIVE: Piriformis muscle syndrome (PMS) is underdiagnosed. To evaluate the potential of diffusion tensor imaging and diffusion tensor tractography as innovative tools for the diagnosis of PMS by functional assessment of the sciatic nerve, the aims of this study are to assess the reproducibility and to evaluate the changes in the parameters at levels proximal and distal to the piriformis. MATERIALS AND METHODS: Fractional anisotropy (FA) and the apparent diffusion coefficient (ADC) of the sciatic nerve at three levels were quantified twice each by two examiners using the fiber-tracking method...
December 27, 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/28011175/atypical-onset-of-sciatica-in-a-patient-with-a-filum-terminale-hemangioblastoma
#18
Tarek Carlos Salman-Monte, Francisco Castro-Dominguez, Gloria Villalba, Jaume Capellades, Jordi Monfort
No abstract text is available yet for this article.
December 20, 2016: Reumatología Clinica
https://www.readbyqxmd.com/read/28003290/surgical-versus-conservative-treatment-for-lumbar-disc-herniation-a-prospective-cohort-study
#19
Marinella Gugliotta, Bruno R da Costa, Essam Dabis, Robert Theiler, Peter Jüni, Stephan Reichenbach, Hans Landolt, Paul Hasler
OBJECTIVES: Evidence comparing the effectiveness of surgical and conservative treatment of symptomatic lumbar disc herniation is controversial. We sought to compare short-term and long-term effectiveness of surgical and conservative treatment in sciatica symptom severity and quality of life in patients with lumbar disc herniation in a routine clinical setting. METHODS: A prospective cohort study of a routine clinical practice registry consisting of 370 patients...
December 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27994785/baastrup-s-disease-is-associated-with-recurrent-of-sciatica-after-posterior-lumbar-spinal-decompressions-utilizing-floating-spinous-process-procedures
#20
Masao Koda, Chikato Mannoji, Masazumi Murakami, Tomoaki Kinoshita, Jiro Hirayama, Tomohiro Miyashita, Yawara Eguchi, Masashi Yamazaki, Takane Suzuki, Masaaki Aramomi, Mitsutoshi Ota, Satoshi Maki, Kazuhisa Takahashi, Takeo Furuya
STUDY DESIGN: Retrospective case-control study. PURPOSE: To determine whether kissing spine is a risk factor for recurrence of sciatica after lumbar posterior decompression using a spinous process floating approach. OVERVIEW OF LITERATURE: Kissing spine is defined by apposition and sclerotic change of the facing spinous processes as shown in X-ray images, and is often accompanied by marked disc degeneration and decrement of disc height. If kissing spine significantly contributes to weight bearing and the stability of the lumbar spine, trauma to the spinous process might induce a breakdown of lumbar spine stability after posterior decompression surgery in cases of kissing spine...
December 2016: Asian Spine Journal
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