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https://www.readbyqxmd.com/read/28915804/prevalence-and-predictors-of-persistent-pelvic-girdle-pain-12%C3%A2-years-postpartum
#1
Cecilia Bergström, Margareta Persson, Kari-Anne Nergård, Ingrid Mogren
BACKGROUND: Pelvic girdle pain (PGP) is not always a self-limiting condition. Women with more pronounced persistent PGP (PPGP) report poorer health status compared to women with less pronounced symptoms. The knowledge concerning the long-term consequences of PPGP is limited, thus more knowledge in this area is needed. The overall aim was to study the prevalence and predictors of PPGP 12 years after delivery. METHODS: This is a long-term follow-up study based on a previous cohort study that commenced in 2002...
September 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28906149/a-rare-cause-of-sciatica-discovered-during-digital-rectal-examination-case-report-of-an-intrapelvic-sciatic-notch-schwannoma
#2
Peter Y M Woo, Jason M K Ho, Joanna W K Ho, Calvin H K Mak, Alain K S Wong, Hoi-Tung Wong, Kwong-Yau Chan
Intrapelvic sciatic nerve schwannomas are rare causes for non-discogenic sciatica. We describe a 44-year-old female who had a palpable mass on digital rectal examination that exhibited a positive Tinel's sign. The schwannoma was excised by a posterior transgluteal approach. Patients with negative spinal imaging should undergo pelvic scanning to rule out these tumors.
September 14, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28904328/a-narrative-review-of-non-operative-treatment-especially-traditional-chinese-medicine-therapy-for-lumbar-intervertebral-disc-herniation
#3
Bo Zhang, Haidong Xu, Juntao Wang, Bin Liu, Guodong Sun
Lumbar intervertebral disc herniation (LIDH), as the main contributor to low back pain and sciatica, imposes a heavy burden on both the individual and society. Non-operative treatment or conservative treatment has proven effective in alleviation of the symptoms of LIDH and are considered to be a first-line choice for most cases. Active lifestyle, physical therapy, complementary and alternative medicine therapy or Traditional Chinese medicine (TCM) therapy, and pharmacotherapy are routinely used as effective non-operative treatment for LIDH patients...
2017: Bioscience Trends
https://www.readbyqxmd.com/read/28873992/genetic-susceptibility-for-sciatica-and-lumbar-disc-herniation
#4
Ziev B Moses, John H Chi
No abstract text is available yet for this article.
July 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28843115/double-level-isthmic-spondylolisthesis-treated-with-posterior-lumbar-interbody-fusion-a-review-of-32-cases
#5
DeYong Song, DeWei Song, KeHui Zhang, Zhong Chen, Feng Wang, TianHang Xuan
OBJECTIVE: The incidence of double-level isthmic spondylolisthesis is rare. The aim of this study is to evaluate the short-term functional and radiological outcomes of surgical treatment for double-level isthmic spondylolisthesis. PATIENTS AND METHODS: Between 2004 and 2014, thirty-two patients with double-level isthmic spondylolisthesis who underwent posterior lumbar interbody fusion (PLIF) with autogenous bone chips were reviewed retrospectively. The clinical outcomes were measured by VAS (Visual analog scale) and JOA(Japanese Orthopedic Association) score...
August 19, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28840995/novel-4-bp-intronic-deletion-c-1560-3_1560-6del-in-lemd3-in-a-korean-patient-with-osteopoikilosis
#6
In Young Yoo, Ju Sun Song, Chang Seok Ki, Jong Won Kim, Hoon Suk Cha, Yong Ki Min
Osteopoikilosis is an autosomal dominant bone disorder characterized by symmetric multiple osteosclerotic lesions throughout the axial and appendicular skeleton. Pathogenic variants in the LEMD3 have been identified as the cause of osteopoikilosis. LEMD3 encodes an inner nuclear membrane protein that interacts with bone morphogenetic protein (BMP) and transforming growth factor (TGF)-β pathways. We report the case of a 19-year-old man presenting with lower back pain and sciatica. His radiograph revealed bilateral and symmetrical multiple osteosclerotic bone lesions in both scapular areas...
November 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28838872/the-value-of-short-term-pain-relief-in-predicting-the-long-term-outcome-of-lumbar-transforaminal-epidural-steroid-injections
#7
Holger Joswig, Armin Neff, Christina Ruppert, Gerhard Hildebrandt, Martin Nikolaus Stienen
BACKGROUND: A previous report demonstrated the predictive power of short-term leg pain relief after lumbar transforaminal epidural steroid injection for 1-month treatment response. The question whether the long-term response could be similarly predicted remained unanswered. METHODS: A prospective cohort of n=57 patients who underwent transforaminal epidural steroid injection for sciatica secondary to a lumbar disc herniation was followed for 24 months. Leg and back pain on the visual analog scale, health-related quality of life with the Short Form-12 and functional outcome with the Oswestry Disability Index were assessed...
August 21, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28836092/four-symptoms-define-the-piriformis-syndrome-an-updated-systematic-review-of-its-clinical-features
#8
REVIEW
Kevork Hopayian, Armine Danielyan
PURPOSE: To update the evidence on the clinical features of the piriformis syndrome since the first systematic review published in 2010. METHOD: A systematic review of all case, cross-sectional and prevalence studies. RESULTS: The commonest features reported were: buttock pain, pain aggravated on sitting, external tenderness near the greater sciatic notch and pain on any maneuver that increases piriformis muscle tension, and limitation of straight leg raising...
August 23, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28812185/reliability-of-standing-weight-bearing-0-25t-mr-imaging-findings-and-positional-changes-in-the-lumbar-spine
#9
Bjarke B Hansen, Philip Hansen, Anders F Christensen, Charlotte Trampedach, Zoreh Rasti, Henning Bliddal, Mikael Boesen
OBJECTIVE: To test the reliability and absolute agreement of common degenerative findings in standing positional magnetic resonance imaging (pMRI). METHODS AND MATERIALS: Low back pain patients with and without sciatica were consecutively enrolled to undergo a supine and standing pMRI. Three readers independently evaluated the standing pMRI for herniation, spinal stenosis, spondylolisthesis, HIZ lesions and facet joint effusion. The evaluation included a semi-quantitative grading of spinal stenosis, foraminal stenosis and spinal nerve root compression...
August 15, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28803493/health-related-quality-of-life-of-people-with-multimorbidity-at-a-community-based-interprofessional-student-assisted-clinic-implications-for-assessment-and-intervention
#10
Zephanie Tyack, Suzanne Kuys, Petrea Cornwell, Kerrie-Anne Frakes, Steven McPhail
Objective This study examined the relationship between the number of comorbidities and health-related quality of life (HRQoL) and between select physical conditions and HRQoL. Differences in HRQoL in comparison to a normative sample were also examined. Method A cross-sectional study among people with multimorbidity ( n = 401) attending a community-based, interdisciplinary health clinic was conducted. HRQoL was measured using the eight dimensions of the SF-36. Multiple linear regression and t-tests were used to analyse the data...
January 1, 2017: Chronic Illness
https://www.readbyqxmd.com/read/28779960/efficacy-and-safety-of-etanercept-in-the-treatment-of-sciatica-a-systematic-review-and-meta-analysis
#11
REVIEW
Shangfei Jing, Chenyuan Yang, Xiaofei Zhang, Shuzheng Wen, Yuankui Li
Etanercept might be promising to alleviate sciatica caused by lumbar disc herniation and spinal stenosis. However, the results remained controversial. We conducted a systematic review and meta-analysis to evaluate the efficacy of etanercept in patients with sciatica. PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases were systematically searched. Randomized controlled trials (RCTs) and Controlled clinical trials (CCT) assessing the efficacy of etanercept on sciatica caused by lumbar disc herniation and spinal stenosis were included...
October 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28762109/dual-lumbar-bronchogenic-and-arachnoid-cyst-presenting-with-sciatica-and-left-foot-drop
#12
Nicholas Candy, Adam Young, Abel Devadass, Andrew Dean, Jason McMillen, Rikin Trivedi
INTRODUCTION: Spinal bronchogenic cysts are rare findings, with only four cases of lumbar bronchogenic cysts reported in the literature. All of these bronchogenic cysts involved the conus medullaris. We present the first case of a lumbar bronchogenic cyst and arachnoid cyst arising from the cauda equina in a 68-year-old male. Uniquely, this bronchogenic cyst also contained components of an arachnoid cyst. METHODS: Magnetic resonance imaging (MRI) demonstrated a compressive cystic lesion at the level of the L3 vertebra splaying the cauda equina...
July 31, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28750940/lifestyle-risk-factors-increase-the-risk-of-hospitalization-for-sciatica-findings-of-four-prospective-cohort-studies
#13
Rahman Shiri, Ulla Euro, Markku Heliövaara, Mirja Hirvensalo, Kirsti Husgafvel-Pursiainen, Jaro Karppinen, Jouni Lahti, Ossi Rahkonen, Olli T Raitakari, Svetlana Solovieva, Yang Xiaolin, Eira Viikari-Juntura, Tea Lallukka
BACKGROUND: To assess the effects of lifestyle risk factors on the risk of hospitalization for sciatica and to determine whether overweight or obesity modifies the effect of leisure-time physical activity on hospitalization for sciatica. METHODS: We included four Finnish prospective cohort studies (Health 2000 Survey, Mobile Clinic Survey, Helsinki Health Study and Young Finns Study) consisting of 34,589 participants and 1259 hospitalizations for sciatica during 12 to 30 years follow-up...
July 24, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28746067/perturbing-nr2b-psd-95-interaction-relieves-neuropathic-pain-by-inactivating-camkii-creb-signaling
#14
Fangxia Xu, Xin Zhao, Lin Liu, Jia Song, Yingjun Zhu, Shuaishuai Chu, Xueming Shao, Xiuxiu Li, Zhengliang Ma, Xiaoping Gu
Neuropathic pain is characterized by central sensitization. The interaction between N-methyl-D-aspartate receptors (NMDARs) and postsynaptic density protein-95 (PSD-95) plays a major role in central sensitization. Here, we aimed to investigate the analgesic effect of disruption of the interaction between NMDAR and PSD-95. Chronic dorsal root ganglia compression model rats were used to mimic sciatica. Thermal hyperalgesia and mechanical allodynia were evaluated. The expression of spinal phospho-NR2B, PSD-95, calcium/calmodulin-dependent protein kinase II (CaMKII), and cAMP response element binding protein (CREB) was measured using western blotting...
September 6, 2017: Neuroreport
https://www.readbyqxmd.com/read/28745066/a-comparison-of-the-efficacy-and-tolerability-of-the-treatments-for-sciatica-a-network-meta-analysis
#15
Jian-Rong Guo, Xiao-Ju Jin, Hua-Chun Shen, Huan Wang, Xun Zhou, Xiao-Qian Liu, Na-Na Zhu
BACKGROUND: There remains a lack of a systematic summary of the efficacy and safety of various medicines for sciatica, and discrepancies among these exist. OBJECTIVE: The aim of this study is to comprehensively assess the efficacy of and tolerance to several medical options for the treatment of sciatica. METHODS: We performed a network meta-analysis and illustrated the results by the mean difference or odds ratio. The surface under the cumulative ranking curve (SUCRA) was used for indicating the preferable treatments...
July 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28741033/refractory-sciatica-caused-by%C3%A2-gluteal-varicosities
#16
Zheng Zhang, Xuebing Zhang, Chen Yang, Xiaoyu Wen
We report a case of sciatica that fulfilled the diagnostic criteria for inferior gluteal vein varicosities according to patient history and on magnetic resonance imaging. Since conservative treatment was ineffective, excision-ligation of the varicose vein was performed as recommended in the previous literature. However, pain was only slightly relieved and then aggravated. Reoperation involving wide release and resection of the piriformis outlet was performed. Pain resolved immediately thereafter. We suggest that this case of sciatica resulted from both piriformis entrapment and vein varicosities...
July 24, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28735122/ventral-lumbar-synovial-cyst-causing-cauda-equina-compression-case-report-and-literature-review
#17
Anan Shtaya, Ahmed-Ramadan Sadek, Mark Walker, Ali Nader-Sepahi
BACKGROUND: Juxtafacet spinal cysts are cystic synovial lesions that are often indistinguishable clinically or radiologically and require histopathology analysis to confirm the diagnosis. Lumbar synovial cysts usually arising from the synovium of the facet joints. They have been described posterolateral or rarely in the posterior midline. However, we describe the first synovial cyst ventral to the dural sac. CASE DESCRIPTION: We report a lumbar 3-4 lesion causing cauda equina compression in a 57-year-old man who presented with 3 months history of low back pain and bilateral sciatica, intermittent urinary incontinence and erectile dysfunction...
July 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28727705/activation-of-the-rage-stat3-pathway-in-the-dorsal-root-ganglion-contributes-to-the-persistent-pain-hypersensitivity-induced-by-lumbar-disc-herniation
#18
Xin-Sheng Zhang, Xiao Li, Hai-Jie Luo, Zhu-Xi Huang, Cui-Cui Liu, Qing Wan, Shu-Wei Xu, Shao-Ling Wu, Song-Jian Ke, Chao Ma
BACKGROUND: Clinically, chronic low back pain and sciatica associated with lumbar disc herniation (LDH) is a common musculoskeletal disorder. Due to the unawareness of detailed mechanisms, it is difficult to get an effective therapy. OBJECTIVE: The aim of the present study was to identify the role of the RAGE/STAT3 pathway in the dorsal root ganglion (DRG) on the formation and development of persistent pain hypersensitivity induced by LDH. STUDY DESIGN: Controlled animal study...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28720992/ganglion-cyst-of-the-hip-mimicking-lumbar-disk-herniation-a-case-report
#19
Devendra Lakhotia, Kumar Prashant, Won Yong Shon
Sciatic nerve compression due to a ganglion cyst around the posterior aspect of the hip joint is not commonly described in literature. We report a rare case of a 63-year-old man with a ganglion cyst around his hip joint, who presented with symptoms of sciatica. After excision of the cyst, the patient was symptom free. A high index of clinical doubt and detailed clinical examination is required for non-palpable cystic lesions in close proximity to the sciatic nerve in patients presenting with symptoms of sciatica and in patients with concomitant of lumbar disk herniation...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28720991/transforaminal-epidural-etanercept-for-the-treatment-of-prolapsed-lumbar-intervertebral-disc-induced-sciatica
#20
Ashish Dagar, Ramesh Kumar, Abhishek Kashyap, Vinay Prabhat, Hitesh Lal, Lalit Kumar
STUDY DESIGN: Hospital based prospective study. OBJECTIVE: To study clinical response of transforaminal epidural Etanercept for lumbar prolapsed intervertebral disc induced sciatica. METHOD: Patients presenting to O.P.D and Emergency services of our hospital were screened for inclusion and exclusion criteria & suitable candidates were enrolled in study. Patients received 2 transforaminal epidural injections of Etanercept 2 mg, 2 weeks apart, and were assessed for efficacy at 2 week, 1 month and 3 months after the second injection...
April 2017: Journal of Clinical Orthopaedics and Trauma
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