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https://www.readbyqxmd.com/read/28213709/high-efficiency-removal-of-triclosan-by-structure-directing-agent-modified-mesoporous-mil-53-al
#1
Rongni Dou, Junya Zhang, Yuancai Chen, Siyuan Feng
In order to expand the potential applications of metal-organic frameworks (MOFs), structure directing agents modified mesoporous MIL-53(Al) (MIL-53(Al)-1) was investigated to adsorb triclosan (TCS) with two different initial concentrations. MIL-53(Al)-1 with high mesoporosity and total pore volume exhibited higher adsorption capacity and 4.4 times faster adsorption of TCS at low concentration (1 mg L(-1)) than that of microporous MIL-53(Al). Also, mesoporous as well as microporous MIL-53(Al) showed significant higher adsorption capacity and two orders of magnitude greater fast uptake of TCS than two kinds of mesoporous-activated carbon...
February 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28211869/non-apoptotic-cell-death-in-animal-development
#2
REVIEW
Lena M Kutscher, Shai Shaham
Programmed cell death (PCD) is an important process in the development of multicellular organisms. Apoptosis, a form of PCD characterized morphologically by chromatin condensation, membrane blebbing, and cytoplasm compaction, and molecularly by the activation of caspase proteases, has been extensively investigated. Studies in Caenorhabditis elegans, Drosophila, mice, and the developing chick have revealed, however, that developmental PCD also occurs through other mechanisms, morphologically and molecularly distinct from apoptosis...
February 17, 2017: Cell Death and Differentiation
https://www.readbyqxmd.com/read/28211501/high-resolution-3d-imaging-of-whole-organ-after-clearing-taking-a-new-look-at-the-zebrafish-testis
#3
Maxence Frétaud, Laurie Rivière, Élodie De Job, Stéphanie Gay, Jean-Jacques Lareyre, Jean-Stéphane Joly, Pierre Affaticati, Violette Thermes
Zebrafish testis has become a powerful model for reproductive biology of teleostean fishes and other vertebrates and encompasses multiple applications in applied and basic research. Many studies have focused on 2D images, which is time consuming and implies extrapolation of results. Three-dimensional imaging of whole organs recently became an important challenge to better understand their architecture and allow cell enumeration. Several protocols have thus been developed to enhance sample transparency, a limiting step for imaging large biological samples...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28210833/energy-transfer-in-anabaena-variabilis-filaments-adapted-to-nitrogen-depleted-and-nitrogen-enriched-conditions-studied-by-time-resolved-fluorescence
#4
Aya Onishi, Shimpei Aikawa, Akihiko Kondo, Seiji Akimoto
Nitrogen is among the most important nutritious elements for photosynthetic organisms such as plants, algae, and cyanobacteria. Therefore, nitrogen depletion severely compromises the growth, development, and photosynthesis of these organisms. To preserve their integrity under nitrogen-depleted conditions, filamentous nitrogen-fixing cyanobacteria reduce atmospheric nitrogen to ammonia, and self-adapt by regulating their light-harvesting and excitation energy-transfer processes. To investigate the changes in the primary processes of photosynthesis, we measured the steady-state absorption and fluorescence spectra and time-resolved fluorescence spectra (TRFS) of whole filaments of the nitrogen-fixing cyanobacterium Anabaena variabilis at 77 K...
February 16, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28209925/the-stress-polarity-pathway-ampk-giv-es-protection-against-metabolic-insults
#5
Pradipta Ghosh
Loss of cell polarity impairs organ development and function; it can also serve as one of the first triggers for oncogenesis. In 2006-2007 two groups simultaneously reported the existence of a special pathway for maintaining epithelial polarity in the face of environmental stressors. In this pathway, AMPK, a key sensor of metabolic stress stabilizes tight junctions, preserves cell polarity, and thereby, maintains epithelial barrier functions. Accumulating evidence since has shown that pharmacologic activation of AMPK by Metformin protects the epithelial barrier against multiple environmental and pathological stressful states and suppresses tumorigenesis...
February 15, 2017: Aging
https://www.readbyqxmd.com/read/28207814/jmjd-5-kdm8-regulates-h3k36me2-and-is-required-for-late-steps-of-homologous-recombination-and-genome-integrity
#6
Pier Giorgio Amendola, Nico Zaghet, João J Ramalho, Jens Vilstrup Johansen, Mike Boxem, Anna Elisabetta Salcini
The eukaryotic genome is organized in a three-dimensional structure called chromatin, constituted by DNA and associated proteins, the majority of which are histones. Post-translational modifications of histone proteins greatly influence chromatin structure and regulate many DNA-based biological processes. Methylation of lysine 36 of histone 3 (H3K36) is a post-translational modification functionally relevant during early steps of DNA damage repair. Here, we show that the JMJD-5 regulates H3K36 di-methylation and it is required at late stages of double strand break repair mediated by homologous recombination...
February 16, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28205549/local-ph-oscillations-witness-autocatalytic-self-organization-of-biomorphic-nanostructures
#7
M Montalti, G Zhang, D Genovese, J Morales, M Kellermeier, J M García-Ruiz
Bottom-up self-assembly of simple molecular compounds is a prime pathway to complex materials with interesting structures and functions. Coupled reaction systems are known to spontaneously produce highly ordered patterns, so far observed in soft matter. Here we show that similar phenomena can occur during silica-carbonate crystallization, the emerging order being preserved. The resulting materials, called silica biomorphs, exhibit non-crystallographic curved morphologies and hierarchical textures, much reminiscent of structural principles found in natural biominerals...
February 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28205515/tailored-protein-encapsulation-into-a-dna-host-using-geometrically-organized-supramolecular-interactions
#8
Andreas Sprengel, Pascal Lill, Pierre Stegemann, Kenny Bravo-Rodriguez, Elisa-C Schöneweiß, Melisa Merdanovic, Daniel Gudnason, Mikayel Aznauryan, Lisa Gamrad, Stephan Barcikowski, Elsa Sanchez-Garcia, Victoria Birkedal, Christos Gatsogiannis, Michael Ehrmann, Barbara Saccà
The self-organizational properties of DNA have been used to realize synthetic hosts for protein encapsulation. However, current strategies of DNA-protein conjugation still limit true emulation of natural host-guest systems, whose formation relies on non-covalent bonds between geometrically matching interfaces. Here we report one of the largest DNA-protein complexes of semisynthetic origin held in place exclusively by spatially defined supramolecular interactions. Our approach is based on the decoration of the inner surface of a DNA origami hollow structure with multiple ligands converging to their corresponding binding sites on the protein surface with programmable symmetry and range-of-action...
February 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28205422/ophthalmologic-wax-models-as-an-educational-tool-for-18th-century-vision-scientists
#9
Fabio Zampieri, Francesco Comacchio, Alberto Zanatta
The Medical Faculties of the University of Padua (Italy) and the University of Vienna (Austria) preserved two series of wax models, made by the Austrian Johann Nepomuk Hoffmayr at the beginning of the 19th century. These models were created in a period of evolution of both medical specialties and organ pathology, which brought morbid organs at the centre of medical investigation. Ceroplastic was considered a useful tool for didactic and research, as it provided a three-dimensional realistically coloured reproduction of organic lesions...
February 16, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28199408/high-quality-rna-extraction-from-the-sea-urchin-paracentrotus-lividus-embryos
#10
Nadia Ruocco, Susan Costantini, Valerio Zupo, Giovanna Romano, Adrianna Ianora, Angelo Fontana, Maria Costantini
The sea urchin Paracentrotus lividus (Lamarck, 1816) is a keystone herbivore in the Mediterranean Sea due to its ability to transform macroalgal-dominated communities into barren areas characterized by increased cover of bare substrates and encrusting coralline algae, reduced biodiversity and altered ecosystem functions. P. lividus is also an excellent animal model for toxicology, physiology and biology investigations having been used for more than a century as a model for embryological studies with synchronously developing embryos which are easy to manipulate and analyze for morphological aberrations...
2017: PloS One
https://www.readbyqxmd.com/read/28199303/mechanical-stretch-triggers-rapid-epithelial-cell-division-through-piezo1
#11
S A Gudipaty, J Lindblom, P D Loftus, M J Redd, K Edes, C F Davey, V Krishnegowda, J Rosenblatt
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body. However, epithelial cell division must be tightly linked to cell death to preserve barrier function and prevent tumour formation. How does the number of dying cells match those dividing to maintain constant numbers? When epithelial cells become too crowded, they activate the stretch-activated channel Piezo1 to trigger extrusion of cells that later die. However, it is unclear how epithelial cell division is controlled to balance cell death at the steady state...
February 15, 2017: Nature
https://www.readbyqxmd.com/read/28199049/towards-organic-zeolites-and-inclusion-catalysts-heptazine-imide-salts-can-exchange-metal-cations-in-the-solid-state
#12
Markus Antonietti, Aleksandr Savateev, Sergey Pronkin, Marc Willinger, Dariya Dontsova
Highly crystalline potassium (heptazine imides) were prepared by the thermal condensation of substituted 1,2,4-triazoles in eutectic salt melts. These semiconducting salts are already known to be highly active photocatalysts, e.g. for the visible light driven generation of hydrogen from water. Herein, we show that within the solid state structure, potassium ions can be exchanged to other metal ions while the crystal habitus is essentially preserved.
February 15, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28198677/decipher-the-ancestry-of-the-plant-specific-lbd-gene-family
#13
Yimeng Kong, Peng Xu, Xinyun Jing, Longxian Chen, Laigeng Li, Xuan Li
BACKGROUND: Lateral Organ Boundaries Domain (LBD) genes arise from charophyte algae and evolve essential functions in land plants in regulating organ development and secondary metabolism. Although diverse plant species have been investigated to construct the phylogeny of LBD gene family, a detailed and reliable ancestry that characterizes their evolutionary patterns has not been revealed. RESULTS: We develop an improved bioinformatic method that allows robust detection of 431 LBD genes in 11 high-quality land plant genomes...
January 25, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28195822/microflora-of-retained-intracochlear-electrodes-from-infected-cochlear-implants
#14
Varun V Varadarajan, Carolyn O Dirain, Patrick J Antonelli
Objectives Cochlear implant infections may be refractory to medical management and require device removal with subsequent reimplantation. During device removal, the intracochlear electrode array is commonly left in place to prevent obliteration of the cochlear lumen. If the electrode is colonized with pathogens, this risks contaminating the replacement implant. In this study, we compare the microorganisms detected on infected cochlear implants against those on the retained electrode using culture and microbial gene-sequencing techniques...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28195482/the-influence-of-interfacial-effects-on-the-photophysics-of-rhodamine-6g-thin-films-on-a-poly-vinylidene-fluoride-surface
#15
Matthew Mullen, William B Euler
The spectral response of ultrathin films of rhodamine 6G (Rh6G) cast onto polyvinylidene fluoride (PVDF) coated glass slides are studied to investigate a perceived fluorescence emission enhancement. Varying the thickness of the Rh6G layer (submonolayer - multiple layers) on the PVDF layer revealed the existence of multiple Rh6G species on the surface, similar to previous reports on glass. Excitation spectra show that J-type excitons are not responsible for an emission enhancement. Trends in the fluorescence emission intensity show that the surface roughness of the PVDF layer prevents the Rh6G molecules from organizing the way they would on a smooth glass surface...
February 14, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28195244/health-technology-assessment-introducing-a-vacuum-based-preservation-system-for-biological-materials-in-the-anatomic-pathology-workflow
#16
R Saliceti, E Nicodemo, A Giannini, A Cortese
INTRODUCTION: The objective of this work is to assess the implementation of a newly introduced medical equipment technology for the vacuum-based preservation of biological materials within an Anatomic Pathology service. METHODS: The approach selected for the analysis is the Health Technology Assessment (HTA ), a comprehensive evaluation method based on relevant scientific evidence and designed to support healthcare decision makers in purchasing, replacing or disposing of technologies...
March 2016: Pathologica
https://www.readbyqxmd.com/read/28194034/high-pressure-carbon-monoxide-preserves-rat-kidney-grafts-from-apoptosis-and-inflammation
#17
Toyofumi Abe, Koji Yazawa, Masayuki Fujino, Ryoichi Imamura, Naoyuki Hatayama, Yoichi Kakuta, Koichi Tsutahara, Masayoshi Okumi, Naotsugu Ichimaru, Jun-Ya Kaimori, Yoshitaka Isaka, Kunihiro Seki, Shiro Takahara, Xiao-Kang Li, Norio Nonomura
Renal ischemia-reperfusion (I/R) injury is unavoidable in kidney transplantation (KTx) and frequently influences both short- and long-term allograft survival. Carbon monoxide (CO) has attracted attention as a medical gas with anti-inflammatory and anti-apoptotic effects. We investigated a new strategy for organ preservation using ex vivo application of high-pressure CO in an experimental rat KTx model. We preserved kidney grafts using a high-pressure chamber filled with mixed gases composed of CO and O2. We found that cold I/R injury resulted in progressive deterioration of renal graft function in University of Wisconsin solution, whereas CO significantly improved renal function...
February 13, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28193419/chemical-stability-of-astaxanthin-integrated-into-a-food-matrix-effects-of-food-processing-and-methods-for-preservation
#18
REVIEW
Alejandra Anahí Martínez-Delgado, Sanghamitra Khandual, Socorro Josefina Villanueva-Rodríguez
Astaxanthin is a carotenoid pigment found in numerous organisms ranging from bacteria to algae, yeasts, plants, crustaceans and fish such as salmon. Technological importance of this pigment emerged from various studies demonstrating that it is a powerful antioxidant, even with higher activity than alpha-tocopherol and other carotenoids. It has been included in various pharmaceutical products because of several beneficial properties. By its nature, astaxanthin is susceptible to degradation and can undergo chemical changes during food processing...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28192076/thermo-mechanical-stress-analysis-of-cryopreservation-in-cryobags-and-the-potential-benefit-of-nanowarming
#19
Prem Solanki, John C Bischof, Yoed Rabin
Cryopreservation by vitrification is the only promising solution for long-term organ preservation which can save millions of lives across the world. One of the challenges in cryopreservation of large-size tissues and organs is to prevent fracture formation due to the tendency of the material to contract with temperature. The current study focuses on a pillow-like shape of a cryobag, while exploring various strategies to reduce thermo-mechanical stress during the rewarming phase of the cryopreservation protocol, where maximum stresses are typically found...
February 9, 2017: Cryobiology
https://www.readbyqxmd.com/read/28192055/a-community-checklist-for-health-sector-resilience-informed-by-hurricane-sandy
#20
Eric S Toner, Meghan McGinty, Monica Schoch-Spana, Dale A Rose, Matthew Watson, Erin Echols, Eric G Carbone
This is a checklist of actions for healthcare, public health, nongovernmental organizations, and private entities to use to strengthen the resilience of their community's health sector to disasters. It is informed by the experience of Hurricane Sandy in New York and New Jersey and analyzed in the context of findings from other recent natural disasters in the United States. The health sector is defined very broadly, including-in addition to hospitals, emergency medical services (EMS), and public health agencies-healthcare providers, outpatient clinics, long-term care facilities, home health providers, behavioral health providers, and correctional health services...
January 2017: Health Security
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