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https://www.readbyqxmd.com/read/28811848/skull-base-tumors-and-tumor-like-lesions-a-pictorial-review
#1
REVIEW
Akira Kunimatsu, Natsuko Kunimatsu
A number of tumors and tumor-like non-neoplastic lesions with different cell types on histology occur in the skull base. A wide variety in disease and lesion appearance often complicates the process of radiological diagnosis. The main role of radiographic imaging is the detection and characterization of skull base lesions, with evaluation of the extent of invasion or preservation of adjacent critical organs. Evaluation of the skull base anatomy and surgical planning by using image guidance are also important for surgeons...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28809829/horizontal-whole-mount-a-novel-processing-and-imaging-protocol-for-thick-three-dimensional-tissue-cross-sections-of-skin
#2
Lucia Salz, Ryan R Driskell
Processing a tissue of interest to generate a microscopic image that supports a scientific argument can be challenging. The acquisition of high-quality microscopic images is not entirely dependent upon the quality of the microscope, but also upon the methods of tissue processing, which often involve multiple critical actions or steps. Furthermore, mesenchymal cell types in the skin and other tissues represent a new challenge for tissue preparation and imaging. Here, we present a complete process, from tissue harvest to microscopy...
August 2, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28808298/standards-for-arsenic-in-drinking-water-implications-for-policy-in-mexico
#3
Andrew T Fisher, Lizbeth López-Carrillo, Brenda Gamboa-Loira, Mariano E Cebrián
Global concern about arsenic in drinking water and its link to numerous diseases make translation of evidence-based research into national policy a priority. Delays in establishing a maximum contaminant level (MCL) to preserve health have increased the burden of disease and caused substantial and avoidable loss of life. The current Mexican MCL for arsenic in drinking water is 25 μg/l (2.5 times higher than the World Health Organization (WHO) recommendation from 1993). Mexico's struggles to set its arsenic MCL offer a compelling example of shortcomings in environmental health policy...
August 14, 2017: Journal of Public Health Policy
https://www.readbyqxmd.com/read/28808033/multiplex-quantitative-cellular-analysis-in-large-tissue-volumes-with-clearing-enhanced-3d-microscopy-ce3d
#4
Weizhe Li, Ronald N Germain, Michael Y Gerner
Organ homeostasis, cellular differentiation, signal relay, and in situ function all depend on the spatial organization of cells in complex tissues. For this reason, comprehensive, high-resolution mapping of cell positioning, phenotypic identity, and functional state in the context of macroscale tissue structure is critical to a deeper understanding of diverse biological processes. Here we report an easy to use method, clearing-enhanced 3D (Ce3D), which generates excellent tissue transparency for most organs, preserves cellular morphology and protein fluorescence, and is robustly compatible with antibody-based immunolabeling...
August 14, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28805266/hypothermic-pulsatile-preservation-of-kidneys-from-uncontrolled-deceased-donors-after-cardiac-arrest
#5
Xavier Matillon, Fabrice Danjou, Palmina Petruzzo, Olivier Thaunat, Thomas Rimmele, Claire Delsuc, Alexandre Faure, Maud Rabeyrin, Vannary Meas Yedid, William Hanf, Emmanuel Morelon, Lionel Badet, Ricardo Codas
Kidneys from uncontrolled donors after cardiac arrest (uDCD) suffer from a period of warm ischemia between cardiac arrest and cold flushing. Aim of the study was to evaluate renal outcomes of uDCD kidneys selected on the basis of renal Resistance Index (RI) and its influence on graft function and survival. The study included 44 kidneys procured from 26 uDCD starting 1.1.2006 until 31.12.2013. The donors (Maastricht category II) underwent cardiopulmonary resuscitation by assisted ventilation and chest compression; the organs were preserved with "in situ" cold perfusion or a normothermic regional perfusion...
August 14, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28805205/erratum-molecular-preservation-of-1-88-ga-gunflint-organic-microfossils-as-a-function-of-temperature-and-mineralogy
#6
Julien Alleon, Sylvain Bernard, Corentin Le Guillou, Johanna Marin-Carbonne, Sylvain Pont, Olivier Beyssac, Kevin D McKeegan, François Robert
This corrects the article DOI: 10.1038/ncomms11977.
August 14, 2017: Nature Communications
https://www.readbyqxmd.com/read/28804783/functional-corticostriatal-connection-topographies-predict-goal-directed-behaviour-in-humans
#7
Andre F Marquand, Koen V Haak, Christian F Beckmann
Anatomical tracing studies in non-human primates have suggested that corticostriatal connectivity is topographically organized: nearby locations in striatum are connected with nearby locations in cortex. The topographic organization of corticostriatal connectivity is thought to underpin many goal-directed behaviours, but these topographies have not been completely characterised in humans and their relationship to uniquely human behaviours remains to be fully determined. Instead, the dominant approach employs parcellations that cannot model the continuous nature of the topography, nor accommodate overlapping cortical projections in the striatum...
August 2017: Nature Human Behaviour
https://www.readbyqxmd.com/read/28804744/reduced-rich-club-connectivity-is-related-to-disability-in-primary-progressive-ms
#8
Jan-Patrick Stellmann, Sibylle Hodecker, Bastian Cheng, Nadine Wanke, Kim Lea Young, Claus Hilgetag, Christian Gerloff, Christoph Heesen, Götz Thomalla, Susanne Siemonsen
OBJECTIVE: To investigate whether the structural connectivity of the brain's rich-club organization is altered in patients with primary progressive MS and whether such changes to this fundamental network feature are associated with disability measures. METHODS: We recruited 37 patients with primary progressive MS and 21 healthy controls for an observational cohort study. Structural connectomes were reconstructed based on diffusion-weighted imaging data using probabilistic tractography and analyzed with graph theory...
September 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/28802943/pregnancy-outcomes-after-transvaginal-sacrospinous-hysteropexy
#9
Sabri Cavkaytar, Mahmut Kuntay Kokanalı, Umit Tasdemir, Melike Doganay, Orhan Aksakal
AIM: To evaluate the pregnancy outcomes in women who underwent transvaginal sacrospinous hysteropexy with the review of the literature STUDY DESIGN: 54 women who underwent transvaginal sacrospinous hysteropexy due to ≥grade 2 uterine prolapse during six-year period were identified from a computer based database. 8 of these who had pregnancy resulted in live birth subsequent to transvaginal sacrospinous hysteropexy were enrolled in this study. They were examined in case of pelvic organ prolapse recurrence and were questioned about their current self satisfaction status and PISQ-12 questionnaire...
August 4, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28802909/variable-prognostic-value-of-blood-pressure-response-to-exercise
#10
Yuko Kato, Shinya Suzuki, Tokuhisa Uejima, Hiroaki Semba, Takeshi Yamashita
AIM: The aim of this study was to evaluate the impact of patient background including exercise capacity on the relationship between the blood pressure (BP) response to exercise and prognosis in patients visiting a cardiovascular hospital. METHODS: A total of 2134 patients who were referred to our hospital underwent symptom-limited maximal cardiopulmonary exercise testing, and were followed through medical records and mail. The BP response to exercise was defined as the difference between peak and rest systolic BP...
August 9, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28802570/organ-preservation-is-less-frequently-performed-in-women-surgically-treated-for-papillary-renal-cell-carcinoma-results-of-a-comprehensive-multicenter-study
#11
Ingmar Wolff, Anna Scavuzzo, Umberto Capitanio, Tobias Klatte, Shahrokh F Shariat, Nina Wagener, Stefan Zastrow, Hendrik Borgmann, Laura-Maria Krabbe, Georg Hutterer, Matthias May, Sabine D Brookman-May
OBJECTIVE: To analyze the impact of gender on clinico-pathological features and survival of patients with surgically treated papillary renal cell carcinoma (RCC) using a comprehensive international multicenter database. MATERIALS AND METHODS: Data of 2,325 patients undergoing surgery for unilateral papillary RCC between 1984 and 2015 in 17 European and North-American centers were retrospectively collated. The impact of clinico-pathological features on the likelihood of nephron-sparing surgery (NSS) was evaluated using a multivariable logistic regression model...
August 9, 2017: Urology
https://www.readbyqxmd.com/read/28802382/evaluation-of-the-possible-protective-role-of-naringenin-on-gentamicin-induced-ototoxicity-a-preliminary-study
#12
I Koçak, S Sarac, E Aydogan, E Şentürk, D Akakın, K Koroglu, Ö F Özer
OBJECTIVES: The purpose of this study is to evaluate the possible protective role of naringenin in gentamicin-induced ototoxicity through an audiological, biochemical and histopathological evaluation. METHODS: This study was conducted on 32 adult male rats that were randomized into 4 groups(control, gentamicin, naringenin + gentamicin, and naringenin). Naringenin was given to the rats via oral gavage in a dose of 50 mg/kg/day during the 14 day study period. Gentamicin was given by the intraperitoneal route in a dose of 120 mg/kg/day...
September 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28801944/the-emergence-of-second-generation-lethal-injection-protocols-a-brief-history-and-review
#13
Daniel R Malcom, Frank Romanelli
The history of capital punishment in the United States is long and controversial. In many cases, lethal injection has brought medical personnel, ethically and professionally charged with preserving life, into the arena of assisting the state in taking life. Recent US Supreme Court decisions, including Baze v. Rees and Glossip v. Gross, have evaluated and condoned lethal injection protocols. Despite the judicial validation of some midazolam-containing protocols, controversy exists as to the level of unconsciousness provided due to the ceiling effects of the drug...
August 12, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28800588/non-lethal-genotyping-of-tribolium-castaneum-adults-using-genomic-dna-extracted-from-wing-tissue
#14
Frederic Strobl, J Alexander Ross, Ernst H K Stelzer
The red flour beetle Tribolium castaneum has become the second most important insect model organism and is frequently used in developmental biology, genetics and pest-associated research. Consequently, the methodological arsenal increases continuously, but many routinely applied techniques for Drosophila melanogaster and other insect species are still unavailable. For example, a protocol for non-lethal genotyping has not yet been adapted but is particularly useful when individuals with known genotypes are required for downstream experiments...
2017: PloS One
https://www.readbyqxmd.com/read/28799082/mathematical-model-of-interaction-between-bacteriocin-producing-lactic-acid-bacteria-and-listeria-part-2-bifurcations-and-applications
#15
Roberta Regina Delboni, Hyun Mo Yang
The big challenge for the food industry is the attending to demands for minimally processed foods, avoiding intense heat treatments and reducing the addition of chemical preservatives, but at the same time ensuring microbiological safety of these products. Lactic acid bacteria are traditionally used in the production of fermented foods. They are responsible for the production of antimicrobial compounds, such as organic acids and bacteriocins, which are protein compounds with bactericidal effect against related species and bacteria such as Listeria monocytogenes and Staphylococcus aureus...
August 10, 2017: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/28798742/preservation-and-significance-of-extracellular-dna-in-ferruginous-sediments-from-lake-towuti-indonesia
#16
Aurèle Vuillemin, Fabian Horn, Mashal Alawi, Cynthia Henny, Dirk Wagner, Sean A Crowe, Jens Kallmeyer
Extracellular DNA is ubiquitous in soil and sediment and constitutes a dominant fraction of environmental DNA in aquatic systems. In theory, extracellular DNA is composed of genomic elements persisting at different degrees of preservation produced by processes occurring on land, in the water column and sediment. Extracellular DNA can be taken up as a nutrient source, excreted or degraded by microorganisms, or adsorbed onto mineral matrices, thus potentially preserving information from past environments. To test whether extracellular DNA records lacustrine conditions, we sequentially extracted extracellular and intracellular DNA from anoxic sediments of ferruginous Lake Towuti, Indonesia...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28797564/impact-of-anxiety-apathy-and-reduced-functional-autonomy-on-perceived-quality-of-life-in-parkinson-s-disease
#17
Alfonsina D'Iorio, Carmine Vitale, Fausta Piscopo, Chiara Baiano, Anna Paola Falanga, Katia Longo, Marianna Amboni, Paolo Barone, Gabriella Santangelo
INTRODUCTION: Parkinson's disease (PD) is characterized by a wide spectrum of non-motor symptoms that may impact negatively on the activities of the patient's daily life and reduce Health-related quality of life (HRQoL). The present study explored the impact of specific non-motor symptoms on the HRQoL in PD. METHODS: Eighty-four outpatients underwent the Montreal Cognitive Assessment (MoCA) assessing global functioning and several questionnaires to assess depression, apathy, impulse control disorders (ICD), anxiety, anhedonia and functional impact of cognitive impairment...
August 5, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/28797118/effect-of-trichoderma-enriched-organic-charcoal-in-the-integrated-wood-protection-strategy
#18
Javier Ribera, Mónica Gandía, Jose F Marcos, Maria Del Carmen Bas, Siegfried Fink, Francis W M R Schwarze
The gradual elimination of chromium from wood preservative formulations results in higher Cu leaching and increased susceptibility to wood decay fungi. Finding a sustainable strategy in wood protection has become of great interest among researchers. The objective of these in vitro studies was to demonstrate the effect of T-720-enriched organic charcoal (biochar) against five wood decay basidiomycetes isolated from strongly damaged poles. For this purpose, the antagonistic potential of Trichoderma harzianum (strain T-720) was confirmed among other four Trichoderma spp...
2017: PloS One
https://www.readbyqxmd.com/read/28796287/optimization-of-ripe-olive-processing-with-a-single-lye-treatment
#19
Manuel Brenes, Concepción Romero, Pedro García-García
The development of a method for darkening black ripe olives during the washing step with a single NaOH treatment and preservation liquid was studied. Olives of the Hojiblanca cultivar were darkened at pilot plant scale, packed, sterilized, and analyzed after 2 mo of storage at ambient temperature. It was found that the use of a mixture of preservation liquid:water at a ratio of 1:1 during the first washing gave rise to darker olives with slightly better firmness and no effect on sensory quality. However, care must be taken with the concentration of acetic acid in the preservation solution, as a content of this organic acid higher than 25 g/L can cause adverse effects on olive color due to the low pH that can be reached in the flesh of the fruit...
August 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28795092/-data-characterizing-microfabricated-human-blood-vessels-created-via-hydrodynamic-focusing
#20
Kyle A DiVito, Michael A Daniele, Steven A Roberts, Frances S Ligler, André A Adams
This data article provides further detailed information related to our research article titled "Microfabricated Blood Vessels Undergo Neovascularization" (DiVito et al., 2017) [1], in which we report fabrication of human blood vessels using hydrodynamic focusing (HDF). Hydrodynamic focusing with advection inducing chevrons were used in concert to encase one fluid stream within another, shaping the inner core fluid into 'bullseye-like" cross-sections that were preserved through click photochemistry producing streams of cellularized hollow 3-dimensional assemblies, such as human blood vessels (Daniele et al...
October 2017: Data in Brief
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