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https://www.readbyqxmd.com/read/29552808/-research-advance-in-metabolism-of-effective-ingredients-from-traditional-chinese-medicines-by-probiotics
#1
REVIEW
Cheng-En Dai, Hai-Long Li, Xiao-Ping He, Fen-Fen Zheng, Hua-Liu Zhu, Liang-Feng Liu, Wei Du
The pharmacological activity of active ingredients from Chinese medicine depends greatly on the microecological environment of probiotics in the human body. After effective ingredients from traditional Chinese medicines are metabolized or biotransformed by probiotics, their metabolites can increase pharmacological activity, and can be absorbed more easily to improve the bioavailability. Therefore, the combination of Chinese medicines with probiotics is the innovation point in R&D of functional food and Chinese medicines, and also a new thinking for the modernization of Chinese medicine...
January 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29495243/-advances-in-research-on-the-relationship-between-intestinal-microecology-and-cardiovascular-diseases
#2
K T Yan, Y Liu, J Gao
No abstract text is available yet for this article.
February 24, 2018: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29461224/-microecological-changes-in-the-intestine-and-its-effect-on-the-condition-of-hard-tissues-of-teeth-in-adolescence
#3
T Shishniashvili, T Suladze, M Makhviladze, M Pkhaladze
On the background of microecological changes in the gastrointestinal tract, mineral and protein metabolism is disrupted, biochemical changes occur in the phosphorus-calcium metabolism in the bones of the skeleton and hard tissues of the teeth. The aim of the research was to study the activity of the caries process, characterized by progressive decalcification, under conditions of microecological changes in the intestine and its effect on the processes of endogenous calcium assimilation in adolescence. Within the frames of the research 68 adolescents aged 11 to 17 years with various degrees of pathology of the gastrointestinal tract were examined...
January 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29445360/the-dynamic-distribution-of-small-tail-han-sheep-microbiota-across-different-intestinal-segments
#4
Hao Zhang, Mingxu Shao, He Huang, Shujuan Wang, Lili Ma, Huining Wang, Liping Hu, Kai Wei, Ruiliang Zhu
The sheep intestinal tract is characterized by a diverse microbial ecosystem that is vital for the host to digest diet material. The importance of gut microbiota (GM) of animals has also been widely acknowledged because of its pivotal roles in the health and well-being of animals. However, there are no relevant studies on GM of small-tail Han sheep, a superior mutton variety domestic in China. In this study, the structure and distribution of gut microflora were studied by high-throughput sequencing technology...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29397594/-efficacy-of-probiotics-on-the-treatment-of-non-alcoholic-fatty-liver-disease
#5
W Wang, L P Shi, L Shi, L Xu
Objective: To study the clinical effect of probiotics in the treatment of non-alcoholic fatty liver disease (NAFLD). Methods: A total of 200 patients with NAFLD were randomly divided into 4 groups: control group (routine treatment group) and combined treatment group A, B and C. Each group had equal patients. The control group received orally polyene phosphatidylcholine capsules; whereas combined group A, B and C were given orally the live "combined Bifidobacterium Lactobacillus and Enterococcus powder" , "two live combined Bacillus subtilis and Enterococcus" , and the both probiotics respectively...
February 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29280118/-effects-of-perioperative-intestinal-microecological-treatment-on-postoperative-complications-and-gastrointestinal-function-in-patients-with-refractory-functional-constipation
#6
Qiyi Chen, Xiaobo Feng, Ling Ni, Hongliang Tian, Guangke Li, Jun Jiang, Ning Li, Jieshou Li
OBJECTIVE: To investigate the effects of perioperative intestinal microecological treatment on postoperative complications and gastrointestinal function in patients with refractory functional constipation by nonrandomized controlled trial. METHODS: A total of 198 patients with refractory functional constipation who underwent Jinling procedure in our department from 2014 to 2015 were prospectively enrolled, and were divided into conventional treatment group (n=100, routine intestinal preparation was used before operation; probiotics and prebiotics were applied if diarrhea or abdominal distention occurred after operation) and microecological treatment group (n=98, routine perioperative management was applied; probiotics, prebiotics and enteral nutrition were administered since 2 weeks before operation; probiotics and prebiotics were given again when exhaust and defecation recovered after operation)...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29280114/-promotion-of-basic-research-in-efficacy-enhancement-of-chronic-constipation
#7
Li Wang, Weidong Tong
The incidence of chronic constipation increases year by year, but it is underestimated in affecting the health of patients. Clinical diagnosis and treatment of chronic intractable constipation is difficult, owing to the diversity of clinical manifestations and the unclear pathogenesis. The basic research is expected to identify the pathophysiological mechanism of chronic intractable constipation in the future, which can find out a ultimate solution approach and improve clinical efficacy. At present there are several basic research ways attracting our attention, including enteric nervous system (such as nerve cells, intestinal neurotransmitters, intestinal sensory nerve regulation mechanism), intestinal smooth muscle cells, Cajal interstitial cells and sacral neuromodulation and intestinal microecology...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29280110/-update-of-the-rome-iiii-criteria-for-functional-constipation
#8
Ting Yu, Liuqin Jiang, Lin Lin
The Rome IIII( criteria were released in May 2016. Based on the development of brain-intestinal axis theory, intestinal microecology, pharmacogenomics and social psychology, the Rome IIII( criteria revise the definition, diagnostic criteria, clinical evaluation process, and treatments of functional constipation (FC). The revisions are as follows: (1) Definition: FC and constipation-predominant irritable bowel syndrome are considered to be on a continuum rather than as independent entities. (2) Diagnostic criteria: the Bristol stool scale type 1, type 2 and spontaneous bowel movements are added in the diagnostic criteria, respectively, refining the criteria for stool consistency and frequency...
December 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29210899/distinct-microbial-populations-exist-in-the-mucosa-associated-microbiota-of-diarrhea-predominant-irritable-bowel-syndrome-and-ulcerative-colitis
#9
Wenting Zhong, Xiaolan Lu, Haitao Shi, Gang Zhao, Yahua Song, Yonghua Wang, Jing Zhang, Yaofeng Jin, Shenhao Wang
GOALS: The goal of this study was to observe the bacterial colonization in the intestinal mucosa in the patients with diarrhea predominant irritable bowel syndrome (IBS-D) and ulcerative colitis (UC), and compare the mucosa-associated microbiota among the IBS-D patients, UC patients and the healthy control, and explore the correlation of the mucosa-associated microbiota with clinical manifestations. STUDY: A total of 20 IBS-D patients, 28 patients with UC (16 active, 12 inactive) and 16 healthy subjects were enrolled in the study...
November 28, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29198923/enteromorpha-and-polysaccharides-from-enteromorpha-ameliorate-loperamide-induced-constipation-in-mice
#10
Xinxiu Ren, Lei Liu, Yaser Gamallat, Bingqiang Zhang, Yi Xin
Slow-transit constipation(STC)is a disease characterized by functional gastrointestinal disorder. Common laxatives used in clinical practice against constipation such as Senna have side effects. Enteromorpha(EP)is a common marine alga, and the polysaccharide extracted from EP has been reported possessing anti-cancer and anti-inflammation effects. The aim of this study is to investigate the effects of EP and Polysaccharides from Enteromorpha (PEP) on loperamide induced constipated mice model and illustrating mechanism of action...
December 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29134144/composition-diversity-and-function-of-intestinal-microbiota-in-pacific-white-shrimp-litopenaeus-vannamei-at-different-culture-stages
#11
Shenzheng Zeng, Zhijian Huang, Dongwei Hou, Jian Liu, Shaoping Weng, Jianguo He
Intestinal microbiota is an integral component of the host and plays important roles in host health. The pacific white shrimp is one of the most profitable aquaculture species commercialized in the world market with the largest production in shrimp consumption. Many studies revealed that the intestinal microbiota shifted significantly during host development in other aquaculture animals. In the present study, 22 shrimp samples were collected every 15 days from larval stage (15 day post-hatching, dph) to adult stage (75 dph) to investigate the intestinal microbiota at different culture stages by targeting the V4 region of 16S rRNA gene, and the microbial function prediction was conducted by PICRUSt...
2017: PeerJ
https://www.readbyqxmd.com/read/29113344/polysaccharides-from-chrysanthemum-morifolium-ramat-ameliorate-colitis-rats-by-modulating-the-intestinal-microbiota-community
#12
Jin-Hua Tao, Jin-Ao Duan, Shu Jiang, Nan-Nan Feng, Wen-Qian Qiu, Yong Ling
The gut microflora dysbiosis has been closely related with the inflammatory bowel disease (IBD). In this study, the effect of polysaccharides from Chrysanthemum morifolium Ramat on the gut microbiota was evaluated by ulcerative colitis (UC) rat model. Physiological and pathological analyses suggested that Chrysanthemum polysaccharides possessed notably protective effects on UC in vivo. Based on the Illumina MiSeq platform, 16S rRNA sequencing of the rat colonic contents indicated that the intestinal flora structure remarkably changed in the model rats and the tendency was alleviated to a certain degree by treatment with different dosages of Chrysanthemum polysaccharides...
October 6, 2017: Oncotarget
https://www.readbyqxmd.com/read/28768551/feed-additive-probiotics-accelerate-yet-antibiotics-delay-intestinal-microbiota-maturation-in-broiler-chicken
#13
Pengfei Gao, Chen Ma, Zheng Sun, Lifeng Wang, Shi Huang, Xiaoquan Su, Jian Xu, Heping Zhang
BACKGROUND: Reducing antibiotics overuse in animal agriculture is one key in combat against the spread of antibiotic resistance. Probiotics are a potential replacement of antibiotics in animal feed; however, it is not clear whether and how probiotics and antibiotics differ in impact on physiology and microbial ecology of host animals. RESULTS: Host phenotype and fecal microbiota of broilers with either antibiotics or probiotics as feed additive were simultaneously sampled at four time points from birth to slaughter and then compared...
August 3, 2017: Microbiome
https://www.readbyqxmd.com/read/28382453/metabolic-adaptation-to-the-aqueous-leaf-extract-of-moringa-oleifera-lam-supplemented-diet-is-related-to-the-modulation-of-gut-microbiota-in-mice
#14
Xiaoyu Gao, Qiuhong Xie, Ling Liu, Ping Kong, Jun Sheng, Hongyu Xiang
The aqueous leaf extract of Moringa oleifera Lam. (LM-A) is reported to have many health beneficial bioactivities and no obvious toxicity, but have mild adverse effects. Little is known about the mechanism of these reported adverse effects. Notably, there has been no report about the influence of LM-A on intestinal microecology. In this study, animal experiments were performed to explore the relationships between metabolic adaptation to an LM-A-supplemented diet and gut microbiota changes. After 8-week feeding with normal chow diet, the body weight of mice entered a stable period, and one of the group received daily doses of 750-mg/kg body weight LM-A by gavage for 4 weeks (assigned as LM); the other group received the vehicle (assigned as NCD)...
June 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28346920/microbial-composition-of-the-initial-colonization-of-newborns
#15
REVIEW
Samuli Rautava
Early-life interaction with indigenous intestinal microbes is a prerequisite for healthy immune and metabolic maturation. Human infants acquire their gut microbiota predominantly from the mother. A considerable inoculum of microbes is received by the neonate during vaginal delivery. Recent observations suggest that human gut colonization may be initiated prenatally by microbes in amniotic fluid, but the significance of this phenomenon remains unknown. After birth, neonatal gut colonization is guided by human milk factors, which selectively promote the growth of specific microbes, as well as by live microbes present in human milk...
2017: Nestlé Nutrition Institute Workshop Series
https://www.readbyqxmd.com/read/28257664/intake-of-total-saponins-and-polysaccharides-from-polygonatum-kingianum-affects-the-gut-microbiota-in-diabetic-rats
#16
Hongli Yan, Jianmei Lu, Yanfang Wang, Wen Gu, Xingxin Yang, Jie Yu
BACKGROUND: The gut microbiota has been reported to play a critical role in metabolic diseases, including in diabetes. Polygonatum kingianum has been used in the treatment of diabetes and related diseases in China for centuries. Total saponins (TSPK) and total polysaccharides (PSPK) were reported to be major types of active constituents of P. kingianum. This research aims at investigation of their therapeutical mechanisms on diabetes based on the regulation of gut microbiota. STUDY DESIGN: Type 2 diabetes (T2D) rats were induced by high-fat diet (HFD) and streptozotocin-injection from male Sprague-Dawley (SD) rats...
March 15, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/28229287/role-of-neurochemicals-in-the-interaction-between-the-microbiota-and-the-immune-and-the-nervous-system-of-the-host-organism
#17
Alexander V Oleskin, Boris A Shenderov, Vladimir S Rogovsky
This work is concerned with the role of evolutionary conserved substances, neurotransmitters, and neurohormones, within the complex framework of the microbial consortium-immune system-nervous system axis in the human or animal organism. Although the operation of each of these systems per se is relatively well understood, their combined effects on the host organism still await further research. Drawing on recent research on host-produced and microbial low-molecular-weight neurochemicals such as biogenic amines, amino acids, and short-chain fatty acids (SCFAs), we suggest that these mediators form a part of a universal neurochemical "language...
September 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28000183/-operation-key-points-and-efficacy-evaluation-of-jinling-procedure-for-mixed-refractory-constipation
#18
Jun Jiang, Qiyi Chen
For chronic transit constipation (STC), surgery should be considered when all pharmacological interventions, biofeedback, and sacral nerve stimulation failed to relieve severe symptoms. Chronic functional constipation can be subdivided into three subtypes: colonic slow-transit constipation, outlet obstruction and mixed refractory constipation. The pathological changes of colonic slow transit and outlet obstruction constipation can influence each other. Mixed refractory constipation accounts for 90.2% of chronic constipation...
December 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/27622371/probiotics-for-the-treatment-of-symptomatic-uncomplicated-diverticular-disease-rationale-and-current-evidence
#19
Carmelo Scarpignato, Anna Bertelé, Antonio Tursi
Changes in the colonic microbiota are critical to the pathogenesis of diverticular complications such as diverticulitis and peridiverticular abscesses. However, more subtle changes in microbiota composition may well be important to the more chronic manifestations of diverticulosis. Some studies have shown the presence of bacterial overgrowth in subgroups of patients with diverticular disease and recent studies, using molecular biology techniques, found an increase of proteobacteria and actinobacteria in patients with symptomatic uncomplicated diverticular disease (SUDD), compared with healthy controls...
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27387020/fecal-microbiota-transplantation-in-combination-with-soluble-dietary-fiber-for-treatment-of-slow-transit-constipation-a-pilot-study
#20
Xiaolong Ge, Hongliang Tian, Chao Ding, Lili Gu, Yao Wei, Jianfeng Gong, Weiming Zhu, Ning Li, Jieshou Li
BACKGROUND AND AIMS: Intestinal microbiota and soluble dietary fiber play an important role in intestinal microecology, which is closely related to gut motility. Regulating intestinal microecology comprised of fecal microbiota transplantation (FMT) or fiber supplementation is becoming a novel therapy for functional gastrointestinal disease. We launched this study to evaluate the efficacy and safety of FMT combined with fiber for slow transit constipation (STC). METHODS: We performed a study of 21 patients with STC...
April 2016: Archives of Medical Research
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