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https://www.readbyqxmd.com/read/29235862/characterization-of-the-b-center-defect-in-diamond-through-the-vibrational-spectrum-a-quantum-mechanical-approach
#1
Simone Salustro, Anna Maria Ferrari, Francesco Silvio Gentile, Jacques Kontak Desmarais, Michel Rérat, Roberto Dovesi
The B-center in diamond, that consists of a vacancy whose 4 first nearest neighbors are nitrogen atoms, has been investigated at the quantum mechanical level with an all electron Gaussian type basis set, hybrid functionals and the periodic supercell approach. In order to simulate various defect concentrations, four cubic supercells have been considered, containing (before the creation of the vacancy) 64, 216, 512 and 1000 atoms, respectively. Whereas the B-center does not affect the Raman spectrum of diamond, several intense peaks appear in the IR spectrum, that should permit to identify this defect...
December 13, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29235841/pp-heterojunction-of-nickel-oxide-decorated-cobalt-oxide-nanorods-for-enhanced-sensitivity-and-selectivity-toward-volatile-organic-compounds
#2
Jun Min Suh, Woonbae Sohn, Young-Seok Shim, Jang-Sik Choi, Young Geun Song, Taemin Ludvic Kim, Jong-Myeong Jeon, Ki Chang Kwon, Kyoung Soon Choi, Chong-Yun Kang, Hyung-Gi Byun, Ho Won Jang
The utilization of p-p isotype heterojunctions is an effective strategy to enhance the gas sensing properties of metal-oxide semiconductors, but most previous studies focused on p-n heterojunctions owing to their simple mechanism of formation of depletion layers. However, a proper choice of isotype semiconductors with appropriate energy bands can also contribute to the enhancement of the gas sensing performance. Herein, we report nickel oxide (NiO)-decorated cobalt oxide (Co3O4) nanorods (NRs) fabricated using multiple-step glancing angle deposition method...
December 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29235681/on-the-birth-and-development-of-psychoanalytic-field-theory-part-2
#3
Martin A Silverman
Advances in Contemporary Psychoanalytic Field Theory: Concept and Further Development. Edited by S. Montana Katz, Roosevelt Cassorla, and Giuseppe Civitarese. London/New York: Routledge, 2017. 212 pp.
October 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/29235528/identification-of-newly-committed-pancreatic-cells-in-the-adult-mouse-pancreas
#4
Mairobys Socorro, Angela Criscimanna, Patricia Riva, Manuj Tandon, Krishna Prasadan, Ping Guo, Abhinav Humar, Sohail Z Husain, Steven D Leach, George K Gittes, Farzad Esni
Multipotent epithelial cells with high Aldehyde dehydrogenase activity have been previously reported to exist in the adult pancreas. However, whether they represent true progenitor cells remains controversial. In this study, we isolated and characterized cells with ALDH activity in the adult mouse or human pancreas during physiological conditions or injury. We found that cells with ALDH activity are abundant in the mouse pancreas during early postnatal growth, pregnancy, and in mouse models of pancreatitis and type 1 diabetes (T1D)...
December 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29235113/postnatal-effects-of-intrauterine-treatment-of-the-growth-restricted-ovine-fetus-with-intra-amniotic-insulin-like-growth-factor-1
#5
A M Spiroski, M H Oliver, A L Jaquiery, T C R Prickett, E A Espiner, J E Harding, F H Bloomfield
Placental insufficiency-mediated fetal growth restriction (FGR) is associated with altered postnatal growth and metabolism, which are, in turn, associated with increased risk of adult disease. Intra-amniotic insulin-like growth factor-1 (IGF1) treatment of ovine FGR increases growth rate in late gestation, but the effects on postnatal growth and metabolism are unknown. We investigated the effects of intra-amniotic IGF1 administration to ovine fetuses with uteroplacental embolisation-induced FGR on phenotypic and physiologic characteristics in the two weeks after birth...
December 12, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29234842/-patients-with-a-wearable-cardioverter-defibrillator-wcd-prescription-function-and-rehabilitation-support
#6
REVIEW
A Schlitt, M Guha, M Noutsias, H H Klein, H U Klein
Assessment of a permanent risk of life-threatening ventricular arrhythmia in patients with severely reduced left ventricular ejection fraction (LVEF <35%), e. g. after myocarditis, dilated cardiomyopathy, acute myocardial infarction, in patients with postpartum cardiomyopathy or implantable cardioverter-defibrillator (ICD) and cardiac resynchronization treatment plus defibrillator (CRT-D) infection with temporary explantation of the system is a medical challenge. This is time-consuming and unsafe because life-threatening ventricular arrhythmias may occur during the time of risk assessment...
December 12, 2017: Herz
https://www.readbyqxmd.com/read/29234782/newborn-screening-of-genetic-mutations-in-common-deafness-genes-with-bloodspot-based-gene-chip-array
#7
Xuehu He, Xiuzhong Li, Yaqi Guo, Yue Zhao, Hui Dong, Jie Dong, Li Zhong, Zhiyun Shi, Yuying Zhang, Mario Soliman, Chunhua Song, Zhijun Zhao
Purpose: This study screens for deafness gene mutations in newborns in the Northwest China population. Method: The 9 sites of 4 common deafness genes (GJB2, GJB3, SLC26A4, and mt 12S rRNA) were detected by bloodspot-based gene chip array in 2,500 newborns. Results: We detected mutations of the 4 genes in 101 (4.04%) newborns; particularly, 0.20% detected the double mutations. In the Hui population, 4.58% of the newborns tested positive for mutations, whereas 4...
December 12, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29234680/myomas-and-adenomyosis-impact-on-reproductive-outcome
#8
REVIEW
Nikos F Vlahos, Theodoros D Theodoridis, George A Partsinevelos
Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evidence implies that submucosal ones have an adverse effect on conception and early pregnancy. A similar effect yet is not quite clear and has been suggested for intramural myomas. Still, it seems reasonable that intramural myomas greater than 4 cm in diameter may negatively impair reproductive outcome...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29234642/ureaplasma-species-differentially-modulate-pro-and-anti-inflammatory-cytokine-responses-in-newborn-and-adult-human-monocytes-pushing-the-state-toward-pro-inflammation
#9
Kirsten Glaser, Christine Silwedel, Markus Fehrholz, Ana M Waaga-Gasser, Birgit Henrich, Heike Claus, Christian P Speer
Background:Ureaplasma species have been associated with chorioamnionitis and preterm birth and have been implicated in the pathogenesis of neonatal short and long-term morbidity. However, being mostly commensal bacteria, controversy remains on the pro-inflammatory capacity of Ureaplasma. Discussions are ongoing on the incidence and impact of prenatal, perinatal, and postnatal infection. The present study addressed the impact of Ureaplasma isolates on monocyte-driven inflammation. Methods: Cord blood monocytes of term neonates and adult monocytes, either native or LPS-primed, were cultured with Ureaplasma urealyticum (U...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29234522/maternal-mental-health-and-child-problem-behaviours-disentangling-the-role-of-depression-and-borderline-personality-dysfunction
#10
Fay Huntley, Nicola Wright, Andrew Pickles, Helen Sharp, Jonathan Hill
Background: It is not known whether associations between child problem behaviours and maternal depression can be accounted for by comorbid borderline personality disorder (BPD) dysfunction. Aim: To examine the contributions of maternal depression and BPD symptoms to child problem behaviours. Method: Depression trajectories over the first-year postpartum were generated using repeated measurement from a general population sample of 997 mothers recruited in pregnancy...
November 2017: BJPsych Open
https://www.readbyqxmd.com/read/29234490/geminin-deficiency-enhances-survival-in-a-murine-medulloblastoma-model-by-inducing-apoptosis-of-preneoplastic-granule-neuron-precursors
#11
Savita Sankar, Ethan Patterson, Emily M Lewis, Laura E Waller, Caili Tong, Joshua Dearborn, David Wozniak, Joshua B Rubin, Kristen L Kroll
Medulloblastoma is the most common malignant brain cancer of childhood. Further understanding of tumorigenic mechanisms may define new therapeutic targets. Geminin maintains genome fidelity by controlling re-initiation of DNA replication within a cell cycle. In some contexts, Geminin inhibition induces cancer-selective cell cycle arrest and apoptosis and/or sensitizes cancer cells to Topoisomerase IIα inhibitors such as etoposide, which is used in combination chemotherapies for medulloblastoma. However, Geminin's potential role in medulloblastoma tumorigenesis remained undefined...
September 2017: Genes & Cancer
https://www.readbyqxmd.com/read/29234460/generalized-enhanced-suffix-array-construction-in-external-memory
#12
Felipe A Louza, Guilherme P Telles, Steve Hoffmann, Cristina D A Ciferri
Background: Suffix arrays, augmented by additional data structures, allow solving efficiently many string processing problems. The external memory construction of the generalized suffix array for a string collection is a fundamental task when the size of the input collection or the data structure exceeds the available internal memory. Results: In this article we present and analyze [Formula: see text] [introduced in CPM (External memory generalized suffix and [Formula: see text] arrays construction...
2017: Algorithms for Molecular Biology: AMB
https://www.readbyqxmd.com/read/29234279/long-term-effects-of-intermittent-adolescent-alcohol-exposure-in-male-and-female-rats
#13
Eva M Marco, Sara Peñasco, María-Donina Hernández, Anabel Gil, Erika Borcel, Marta Moya, Elena Giné, José Antonio López-Moreno, Consuelo Guerri, Meritxell López-Gallardo, Fernando Rodríguez de Fonseca
Alcohol is a serious public health concern that has a differential impact on individuals depending upon age and sex. Patterns of alcohol consumption have recently changed: heavy episodic drinking-known as binge-drinking-has become most popular among the youth. Herein, we aimed to investigate the consequences of intermittent adolescent alcohol consumption in male and female animals. Thus, Wistar rats were given free access to ethanol (20% in drinking water) or tap water for 2-h sessions during 3 days, and for an additional 4-h session on the 4th day; every week during adolescence, from postnatal day (pnd) 28-52...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29234270/mouse-panx1-is-dispensable-for-hearing-acquisition-and-auditory-function
#14
Veronica Zorzi, Fabiola Paciello, Gaia Ziraldo, Chiara Peres, Flavia Mazzarda, Chiara Nardin, Miriam Pasquini, Francesco Chiani, Marcello Raspa, Ferdinando Scavizzi, Andrea Carrer, Giulia Crispino, Catalin D Ciubotaru, Hannah Monyer, Anna R Fetoni, Anna M Salvatore, Fabio Mammano
Panx1 forms plasma membrane channels in brain and several other organs, including the inner ear. Biophysical properties, activation mechanisms and modulators of Panx1 channels have been characterized in detail, however the impact of Panx1 on auditory function is unclear due to conflicts in published results. To address this issue, hearing performance and cochlear function of the Panx1-/- mouse strain, the first with a reported global ablation of Panx1, were scrutinized. Male and female homozygous (Panx1-/-), hemizygous (Panx1+/-) and their wild type (WT) siblings (Panx1+/+) were used for this study...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29234019/analysis-of-the-cervical-microbiome-and-potential-biomarkers-from-postpartum-hiv-positive-women-displaying-cervical-intraepithelial-lesions
#15
Gislaine Curty, Raquel L Costa, Juliana D Siqueira, Angela I Meyrelles, Elizabeth S Machado, Esmeralda A Soares, Marcelo A Soares
The cervical microbiota composition and diversity of HIV-positive women in the postpartum period is unknown. Using a high-throughput bacterial 16S rRNA gene sequencing, we identified four community state types (CSTs). CST III (Lactobacillusdominant) and CST IV (IV-A, IV-B.1, IV-B.2; high-diversity) were found in 41% and 59% of samples, respectively. We did not find association of any CST to postpartum period (six or twelve months), HPV infection or cytology (normal or lesion). However, five bacterial genera were associated with cervical lesions (Gardnerella, Aerococcus, Schlegelella, Moryella and Bifidobacterium), with significant odds ratio (OR) of 40 (2...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29233896/retargeting-lentiviruses-via-spycatcher-spytag-chemistry-for-gene-delivery-into-specific-cell-types
#16
Nagarjun Kasaraneni, Ana M Chamoun-Emanuelli, Gus Wright, Zhilei Chen
We report a simple strategy for the creation of lentiviral vectors specific to any desired target cells. SpyTag is inserted into an engineered Sindbis virus envelope protein and displayed on the lentivirus surface to create Sindbis virus-SpyTag pseudoparticles (Sind-SpyTag-pp). The SpyTag serves as the covalent anchoring site for a target-cell-specific cell-binding protein (CBP) that is fused to a truncated SpyCatcher (SpyCatcherΔ). Target-cell-specific lentiviruses are created by mixing the Sind-SpyTag-pp and CBP-SpyCatcherΔ in vitro We first used a HER2-binding designed ankyrin repeat protein (DARPin...
December 12, 2017: MBio
https://www.readbyqxmd.com/read/29233670/safety-and-efficacy-of-lumen-apposing-metal-stents-with-and-without-simultaneous-double-pigtail-plastic-stents-for-draining-pancreatic
#17
Murad Aburajab, Zachary Smith, Abdul Khan, Kulwinder Dua
BACKGROUND AND AIMS: Lumen-apposing metal stents (LAMSs) are used to perform necrosectomy in walled-off necrosis (WON). Although necrosectomy is not required for pancreatic pseudocyst (PP), an increasing number of PPs are also being drained with LAMSs in view of their ease of deployment. The aim of the present study was to evaluate the safety and efficacy of using LAMSs to drain PPs. METHODS: At one tertiary center, from January 2014 to May 2016, all consecutive patients with PPs were drained by LAMSs, and the data were retrospectively reviewed...
December 9, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29233668/expression-of-hmgb1-in-maternal-exposure-to-fine-particulate-air-pollution-induces-lung-injury-in-rat-offspring-assessed-with-micro-ct
#18
Wenting Tang, Suran Huang, Lili Du, Wen Sun, Zhiqiang Yu, Yanmei Zhou, Jingsi Chen, Xiuying Li, Xiaomei Li, Bolan Yu, Dunjin Chen
OBJECTIVES: Maternal particulate matter with less than 2.5 μm in diameter (PM2.5) is associated with an increased risk for acute lower respiratory infections and allergic airway inflammation; however, its effect on the developing lung remains unclear. The aim of this study is to determine the effect of maternal PM2.5 during pregnancy on lung development in offspring. METHODS: Timed pregnant Sprague-Dawley rats were treated with PM2.5 (0.1, 0.5, 2.5, or 7.5 mg/kg) once every 3 days from day 0-18 of pregnancy and delivered at term...
December 9, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/29233621/corrigendum-to-eeg-signatures-accompanying-auditory-figure-ground-segregation-neuroimage-2017-volume-141-pp-108-119
#19
Brigitta Tóth, Zsuzsanna Kocsis, Gábor P Háden, Ágnes Szerafin, Barbara G Shinn-Cunningham, István Winkler
No abstract text is available yet for this article.
December 9, 2017: NeuroImage
https://www.readbyqxmd.com/read/29233554/accelerated-and-improved-differentiation-of-retinal-organoids-from-pluripotent-stem-cells-in-rotating-wall-vessel-bioreactors
#20
Tyler DiStefano, Holly Yu Chen, Christopher Panebianco, Koray Dogan Kaya, Matthew J Brooks, Linn Gieser, Nicole Y Morgan, Tom Pohida, Anand Swaroop
Pluripotent stem cells can be differentiated into 3D retinal organoids, with major cell types self-patterning into a polarized, laminated architecture. In static cultures, organoid development may be hindered by limitations in diffusion of oxygen and nutrients. Herein, we report a bioprocess using rotating-wall vessel (RWV) bioreactors to culture retinal organoids derived from mouse pluripotent stem cells. Organoids in RWV demonstrate enhanced proliferation, with well-defined morphology and improved differentiation of neurons including ganglion cells and S-cone photoreceptors...
December 1, 2017: Stem Cell Reports
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