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Transient ischemic dilation ratio

George Angelidis, Maria Samara, Maria Papathanassiou, Maria Satra, Varvara Valotassiou, Ioannis Tsougos, Dimitrios Psimadas, Chara Tzavara, Sotiria Alexiou, John Koutsikos, Nikolaos Demakopoulos, Gregory Giamouzis, Filippos Triposkiadis, John Skoularigis, Panagoula Kollia, Panagiotis Georgoulias
BACKGROUND: Renin-angiotensin-aldosterone system (RAAS) has an important role in atherosclerosis. We investigated the effects of six RAAS gene polymorphisms on myocardial perfusion. METHODS AND RESULTS: We examined 810 patients with known or suspected coronary artery disease (CAD) using stress-rest myocardial single-photon emission computed tomography. Summed stress score (SSS), summed rest score (SRS), summed difference score (SDS), transient ischemic dilation (TID), and lung/heart ratio (LHR) were recorded...
January 17, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
A Jauhal, S Harenberg, J J Crawford, I Bare, B Prasad, L Zahorski, G Ollenberger, V Trivedi, V Chopra, A Shoker, A Lavoie, P Dehghani
Cardiac risk assessment for asymptomatic patients awaiting renal transplantation is controversial. Patients awaiting renal transplantation in Southern Saskatchewan from 2005 to 2015 were retrospectively reviewed. Patients underwent cardiac risk stratification with stress myocardial perfusion scan. Baseline clinical characteristics, nuclear scan results, all-cause mortality, and cardiovascular events were analyzed. Abnormal scans were defined as studies with reversible defects, wall motion abnormalities, lung uptake, or transient ischemic dilation...
November 2017: Transplantation Proceedings
Bruno Lefort, Matthias Lachaud, Jean Marc El Arid, Paul Neville, Nathalie Soulé, Patrice Guérin, Alain Chantepie
BACKGROUND: Several publications have considered results of percutaneous angioplasty for aortic recoarctation, but none focused on procedures performed in children aged<1 year. AIMS: To describe the immediate and midterm results of balloon angioplasty for recoarctation before the age of 1 year, and to define the factors that might influence outcome. METHODS: We retrospectively reviewed data from 20 consecutive children undergoing percutaneous dilatation for aortic recoarctation before the age of 1 year in the University Hospitals of Tours and Nantes...
October 10, 2017: Archives of Cardiovascular Diseases
Mohamed Alama, Christopher Labos, Handel Emery, Robert M Iwanochko, Michael Freeman, Mansoor Husain, Douglas S Lee
BACKGROUND: Transient ischemic dilatation (TID) of the left ventricle is a potential marker of high risk obstructive coronary artery disease on stress myocardial perfusion imaging (MPI). There is, however, interstudy variation in the diagnostic performance of TID for identification of severe and extensive coronary disease anatomy, and varied prognostic implications in the published literature. METHODS: We searched MEDLINE, EMBASE, and COCHRANE databases for studies where TID was compared with invasive or CT coronary angiography for evaluation of coronary artery stenosis...
September 25, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Yehuda Paz, Rachelle Morgenstern, Richard Weinberg, Mariana Chiles, Navdeep Bhatti, Ziad Ali, Sumit Mohan, Sabahat Bokhari
Cardiovascular disease is the leading cause of death in patients with end-stage renal disease (ESRD) and often goes undetected. Abnormal coronary flow reserve (CFR), which predicts increased risk of cardiac death, may be present in patients with ESRD without other evidence of coronary artery disease (CAD). We prospectively studied 131 patients who had rest and dipyridamole pharmacologic stress N13 -ammonia positron emission tomography myocardial perfusion imaging (PET MPI) for kidney transplant evaluation. Thirty-four patients also had left heart catheterization...
December 1, 2017: American Journal of Cardiology
Manolo Rubio, Andre Dias, Nikoloz Koshkelashvili, Jose N Codolosa, Mauricio Jalife-Bucay, Mary Rodriguez-Ziccardi, Aman M Amanullah
Single isotope 99mTc single-photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI) is the most commonly used protocol for nuclear stress testing. Transient ischemic dilation of the left ventricle (TID) has been considered a specific marker of severe coronary artery disease (CAD). Recent publications have questioned the clinical utility of TID, specifically with regadenoson as a stressor and 4DM-SPECT software for TID analysis. These findings have not been demonstrated using other imaging packages...
July 2017: World Journal of Nuclear Medicine
Arash Gholoobi, Narjess Ayati, Alireza Baghyari, Mohsen Mouhebati, Baharak Atar, Vahid Reza Dabbagh Kakhki
After dipyridamole infusion, electrocardiographic (ECG), blood pressure and heart rate (HR) changes were seen. We tried to investigate whether there is a relationship between hemodynamic, ECG and HR changes after dipyridamole infusion and gated myocardial perfusion SPECT findings. We studied 206 consecutive patients which underwent a 2-day protocol Dipyridamole Stress/Rest Tc99m-Sestamibi gated myocardial perfusion SPECT. Systolic blood pressure (SBP), diastolic blood pressure (DBP), HR and ECG were recorded...
June 2017: International Journal of Cardiovascular Imaging
Promporn Suksaranjit, Christopher J McGann, Nazem Akoum, Joseph Biskupiak, Gregory J Stoddard, Eugene G Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F Marrouche, Brent D Wilson
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with coronary artery disease, previous myocardial infarction, or hypertrophic or dilated cardiomyopathy were excluded. The end points of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death, myocardial infarction, and ischemic stroke/transient ischemic attack...
October 1, 2016: American Journal of Cardiology
Zenith A Jameria, Mouhamad Abdallah, Alok Dwivedi, Erica Washburn, Naseer Khan, Mahyar Khaleghi, Nischelle Kalakota, Myron C Gerson
BACKGROUND: Transient ischemic dilation (TID) of the left ventricle (LV) has not been validated as a marker of extensive coronary artery disease (CAD) for studies using a cadmium-zinc-telluride (CZT) camera with upright imaging. METHODS: TID ratios were obtained from upright stress and rest images on a CZT camera. Separate cut-off values were determined for exercise and for regadenoson stress. The cutoffs were then applied to 28 patients with extensive CAD and 101 patients without extensive CAD...
October 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Peter M Okin, Hooman Kamel, Sverre E Kjeldsen, Richard B Devereux
BACKGROUND: Recent findings in population-based studies suggest that abnormal P wave terminal force in lead V1 (PTFV1), a marker of left atrial abnormalities such as fibrosis, dilatation and elevated filling pressures, is associated with incident ischemic stroke, even in the absence of atrial fibrillation. However, whether PTFV1 predicts incident stroke in hypertensive patients during blood pressure lowering has not been examined. METHODS: Risk of incident stroke was examined in relation to abnormal PTFV1 on a baseline ECG in 7778 hypertensive patients with ECG left ventricular hypertrophy, no history of atrial fibrillation, in sinus rhythm on their baseline ECG with no incident atrial fibrillation during follow-up, who were randomly assigned to losartan-based or atenolol-based treatment...
September 2016: Journal of Hypertension
Haruki Tanaka, Teruyuki Takahashi, Nami Kozono, Yoshiki Tanakamaru, Norihiko Ohashi, Yuji Yasunobu, Koichi Tanaka, Takenori Okada, Shunichi Kaseda, Toshio Nakanishi, Yasuki Kihara
Although fractional flow reserve (FFR) and myocardial perfusion imaging (MPI) findings fundamentally differ, several cohort studies have revealed that these findings correlate. Here, we investigated whether flow-limiting FFR could be predicted from adenosine stress thallium-201 MPI with single-photon emission computed tomography (SPECT) findings derived from 84 consecutive, prospectively identified patients with stable coronary artery disease and 212 diseased vessels. Among them, FFR was measured in 136 diseased vessels (64%)...
May 1, 2016: American Journal of Cardiology
Davis Lester, Stephanie El-Hajj, Ayman A Farag, Pradeep Bhambhvani, Lindsey Tauxe, Jaekyeong Heo, Ami E Iskandrian, Fadi G Hage
BACKGROUND: Transient ischemic dilation (TID) of the left ventricle seen on myocardial perfusion imaging (MPI) is sometimes used as a marker of severe coronary artery disease. The prognostic value of TID obtained using regadenoson, a selective adenosine A2A receptor agonist, as a stress agent for MPI has not been studied. METHODS: TID ratio was measured using an automated software program on consecutive patients with normal and abnormal perfusion pattern on regadenoson MPI at a single institution...
October 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Chia-Ju Liu, Yen-Wen Wu, Kuan-Yin Ko, Yi-Chieh Chen, Mei-Fang Cheng, Ruoh-Fang Yen, Kai-Yuan Tzen
PURPOSE: Myocardial perfusion imaging (MPI) using gated single-photon emission tomography (gSPECT) may underestimate the severity of coronary artery disease (CAD). This study aimed to evaluate the significance of combined parameters derived from gSPECT, as well as treadmill stress test parameters, in the detection of severe CAD. METHODS: A total of 211 consecutive patients referred for exercise MPI between June 2011 and June 2013 (who received invasive coronary angiography within six months after MPI) were retrospectively reviewed...
2015: PloS One
Maryam Chavoshi, Armaghan Fard-Esfahani, Babak Fallahi, Alireza Emami-Ardekani, Davood Beiki, Arman Hassanzadeh-Rad, Mohammad Eftekhari
OBJECTIVES: Coronary artery disease is the leading cause of mortality worldwide. The goal of this study is to determine the prognostic value of semiquantitative parameters of electrocardiogram-gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) in a large Middle Eastern (Iranian) population. MATERIALS AND METHODS: This study was a prospective study including all patients referred to our center for myocardial perfusion scan...
July 2015: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
Feng-Di Liu, Rong Zhao, Shuo Wang, Wen-Ting Li, Xiao-Xiao Tao, Ting Sun, Xiao-Lei Shen, Jian-Ren Liu
BACKGROUND: Here we report a rare case of repeated transient Wallenberg's syndrome and discuss its mechanism. METHODS: Case report and literature review. RESULTS: A 57-year-old man was admitted for 1.5-month repeated transient Wallenberg's syndrome, including right-sided Horner's syndrome, lower limb weakness, and paresthesia on the right side of the body and face. His symptom appeared mostly during physical activity. Symptoms occurred nearly everyday and lasted from 5 minutes to 30 minutes...
August 2015: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Mamoru Murakami, Taketo Hatano, Akinori Miyakoshi, Daisuke Arai, Susumu Yamaguchi, Eiji Ogino, Ryo Ohtani, Tetsuya Tsukahara
BACKGROUND AND PURPOSE: We assessed whether intentional undersized dilatation of targeted lesions during carotid artery stenting (CAS) carried a higher risk of in-stent restenosis (ISR) and correlation to subsequent ischemic stroke in qualifying arteries in the follow-up period. METHODS: Consecutive patients undergoing CAS between April 2003 and May 2010 were retrospectively reviewed. The use of a filter device as a distal embolic protection device (EPD) was first approved by Japanese governmental health insurance in April 2008; previously, transient balloon occlusion was used off-label...
2015: British Journal of Neurosurgery
Yasmeen Golzar, Adebayo Olusanya, Nadith Pe, Sumeet G Dua, Jaafer Golzar, Claudia Gidea, Rami Doukky
BACKGROUND: The critical threshold and clinical significance of transient ischemic dilation (TID) for regadenoson, single-isotope (99m)Tc SPECT myocardial perfusion imaging (MPI) are not defined. METHODS: From 100 patients with low likelihood of CAD, we derived the abnormal TID threshold (mean + 2 SD). We validated the threshold in a cohort of 547 patients who received one-day, rest/regadenoson-stress, (99m)Tc-tetrofosmin SPECT-MPI followed by coronary angiography within 6 months...
June 2015: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Paulo W Pires, Saavia S Girgla, Guillermo Moreno, Jonathon L McClain, Anne M Dorrance
Hypertension causes vascular inflammation evidenced by an increase in perivascular macrophages and proinflammatory cytokines in the arterial wall. Perivascular macrophage depletion reduced tumor necrosis factor (TNF)-α expression in cerebral arteries of hypertensive rats and attenuated inward remodeling, suggesting that TNF-α might play a role in the remodeling process. We hypothesized that TNF-α inhibition would improve middle cerebral artery (MCA) structure and reduce damage after cerebral ischemia in hypertensive rats...
September 1, 2014: American Journal of Physiology. Heart and Circulatory Physiology
Asim Aldhilan, Ghulam M S Syed, Ihab Suleiman, M Al Zaibag, Henry Fielding
OBJECTIVE: A high transient ischemic dilatation ratio (TID) for the left ventricle (LV) from a gated myocardial perfusion imaging (G-MPI) study is widely believed to be associated with significant coronary artery disease (CAD). We have investigated the relationship between TID and CAD for our male Saudi Arabian patient population. METHODS: In this retrospective study, all male Saudi Arabian patients who underwent a two-day G-MPI study using Tc99m MIBI during the year 2011 having a TID ⩾ 1...
January 2014: Journal of the Saudi Heart Association
Mario Petretta, Wanda Acampa, Stefania Daniele, Maria Piera Petretta, Monica Plaitano, Alberto Cuocolo
BACKGROUND: We prospectively evaluated the incremental prognostic value of transient ischemic dilation (TID) in patients with type 2 diabetes mellitus during long-term follow-up and estimated cardiac death and nonfatal myocardial infarction (MI) using traditional approaches of prognostication to more recent methods. METHODS AND RESULTS: A total of 672 consecutive diabetic patients with available rest and stress gated myocardial perfusion single-photon emission computed tomographic data were enrolled...
November 2013: Circulation. Cardiovascular Imaging
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