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https://www.readbyqxmd.com/read/28923621/extended-spectrum-beta-lactamase-producing-enterobacteriaceae-related-urinary-tract-infection-in-kidney-transplant-recipients-risk-factors-treatment-and-long-term-outcome
#1
S Brakemeier, S I Taxeidi, B Zukunft, D Schmidt, J Gaedeke, M Dürr, S Hansen, K Budde
BACKGROUND: Prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has risen in kidney transplant (KT) patients, with no long-term data so far on graft function or survival. METHODS: KT patients with ESBL-E-positive urine culture were retrospectively analyzed regarding initial adequate antimicrobial therapy, recurrent infection, transplant function, and survival compared with an ESBL-E-negative KT control cohort. RESULTS: ESBL-E-positive KT patients (n = 93) were older (55...
October 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28919833/conventional-culture-versus-nucleic-acid-amplification-tests-for-screening-of-urethral-neisseria-gonorrhea-infection-among-asymptomatic-men-who-have-sex-with-men
#2
Jiratha Budkaew, Bandit Chumworathayi, Chamsai Pientong, Tipaya Ekalaksananan
BACKGROUND: Many methods are used to detect urethral Neisseria gonorrhea (NG) infection among asymptomatic men who have sex with men (MSM). The objective of this study was to define the performance of conventional culture compared to real-time polymerase chain reaction (PCR) for diagnosis of asymptomatic urethral gonorrhea among MSM. METHODS: In this cross-sectional study, 147 clinical specimens for NG testing from asymptomatic participants were evaluated. MSM >18 years old who consented to undergo urethral swab and collection of urine samples from two clinics (one was the sexually transmitted diseases (STDs) mobile clinic and the second was the antiretroviral clinic) located in Khon Kaen, Thailand, were recruited...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28919055/antimicrobial-resistance-in-women-with-urinary-tract-infection-in-primary-care-no-relation-with-type-2-diabetes-mellitus
#3
Johanna E M Vinken, Helen E Mol, Theo J M Verheij, Sanne van Delft, Marion Kolader, Miquel B Ekkelenkamp, Guy E H M Rutten, Berna D L Broekhuizen
AIMS: To determine if type 2 diabetes mellitus (T2DM) is associated with the spectrum of uropathogens and antimicrobial resistance in urinary tract infections (UTI) in primary care. METHODS: A cross-sectional study in female outpatients ≥30 years with positive urine cultures. T2DM patients were 1:1 matched to controls by age group and general practitioner (GP). GPs were sent questionnaires for additional data. Uropathogens and resistance patterns were compared between patients with and without T2DM...
September 14, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28906365/the-antibiotic-susceptibility-patterns-of-uropathogens-among-children-with-urinary-tract-infection-in-shiraz
#4
Gholamreza Pouladfar, Mitra Basiratnia, Mojtaba Anvarinejad, Pejman Abbasi, Fatemeh Amirmoezi, Samaneh Zare
Urinary tract infection (UTI) is one of the most common bacterial infections in pediatrics. Delay in diagnosis and treatment can cause significant morbidity. The physicians knowledge regarding the symptoms, microorganisms that caused UTI, and effective antibiotics in a geographical area can help them to select the appropriate antibiotics. This study was performed to determine the prevalence of bacteria that cause UTI and their susceptibility to common antibiotics as well as the common symptoms and associated factors in children of Shiraz, Southern Iran...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28903867/detection-accuracy-of-renibacterium-salmoninarum-in-chinook-salmon-oncorhynchus-tshawytscha-walbaum-from-non-lethally-collected-samples-effects-of-exposure-route-and-disease-severity
#5
Carolyn A Richards, Cheryl A Murphy, Travis O Brenden, Thomas P Loch, Mohamed Faisal
Bacterial kidney disease (BKD), caused by Renibacterium salmoninarum, threatens salmonid populations throughout the Northern hemisphere. Many fishery regulatory authorities require ongoing disease monitoring in hatcheries and spawning runs prior to gamete collection to prevent BKD outbreaks and spread. According to diagnostic protocols of the American Fisheries Society-Fish Health Section, monitoring for R. salmoninarum generally consists of lethal sampling of visceral organs from fish. However, non-lethal sampling would be preferable, especially for valuable broodstock or endangered species...
September 15, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28902383/-bcgitis-with-involvement-of-lung-liver-and-bone-marrow%C3%A2-after-immunotherapy-of-urothelial-cancer
#6
Hilte Friederike Geerdes-Fenge, Franziska Stubbe, Micha Löbermann, Philipp Warnke, Andreas Erbersdobler, Emil Christian Reisinger
Medical history A 77-year-old patient with transurethral resection of a bladder tumor was transferred due to persistent fever and progressive dyspnea despite antibiotic therapy for suspected urinary tract infection. Repeating the medical history revealed that a BCG immunotherapy of his non-muscle-invasive bladder carcinoma was performed the day before fever developed. Therefore, BCGitis was suspected. Examinations Laboratory parameters showed pancytopenia, elevated liver enzymes, eleveated C-reactive protein and hypoxemia...
September 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28899877/multiresistant-e-coli-urine-infections-in-children-a-case-control-study
#7
Gayathri Raman, Brendan McMullan, Peter Taylor, Kylie-Ann Mallitt, Sean E Kennedy
OBJECTIVE: Urinary tract infections (UTIs) caused by resistant organisms are increasing which poses challenges when selecting empirical antimicrobial therapy. The aim of this study is to determine risk factors for multiresistant Escherichia coliUTIs in children. DESIGN: We included all reported urinary isolates from a children's hospital collected between January 2010 and June 2013. Patients who had multiresistant E. coliUTIs were identified and a retrospective review of medical records performed...
September 12, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28894842/retroperitoneal-actinomycosis-a-rare-sequela-of-an-infected-obstructing-ureteral-stone
#8
Elizabeth Bearrick, Colby A Dixon, Joshua Rhein, Michael S Borofsky
Background: Actinomycosis is a condition in which Actinomyces, a normal component of the oral and gastrointenstial flora, becomes pathogenic in the setting of damaged tissue, leading to widespread tissue destruction across fascial planes. Prior literature describing this condition is rare, particularly cases involving the retroperitoneum. In this study, we report a case of retroperitoneal actinomycosis caused by an infected, obstructing ureteral stone. Case Presentation: A 48-year-old woman with a history of substance abuse, malnutrition, and gastric bypass presented to the emergency room with a 3-week history of abdominal pain and fevers...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28894690/management-of-asymptomatic-bacteriuria-urinary-catheters-and-symptomatic-urinary-tract-infections-in-patients-undergoing-surgery-for-joint-replacement-a-position-paper-of-the-expert-group-infection-of-swissorthopaedics
#9
REVIEW
Parham Sendi, Olivier Borens, Peter Wahl, Martin Clauss, Ilker Uçkay
In this position paper, we review definitions related to this subject and the corresponding literature. Our recommendations include the following statements. Asymptomatic bacteriuria, asymptomatic leukocyturia, urine discolouration, odd smell or positive nitrite sediments are not an indication for antimicrobial treatment. Antimicrobial treatment of asymptomatic bacteriuria does not prevent periprosthetic joint infection, but is associated with adverse events, costs and antibiotic resistance development. Urine analyses or urine cultures in asymptomatic patients undergoing orthopaedic implants should be avoided...
2017: Journal of bone and joint infection
https://www.readbyqxmd.com/read/28893132/prediction-of-infection-caused-by-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-development-of-a-clinical-decision-making-nomogram
#10
Ana García-Tello, Helena Gimbernat, Cristina Redondo, Elisa Meilán, David M Arana, Juana Cacho, Juan F Dorado, Javier C Angulo
OBJECTIVE: This study aimed to assess the population at risk of infection by extended-spectrum beta-lactamase (ESBL)-producing organisms, using clinical criteria. MATERIALS AND METHODS: All urine cultures positive for Enterobacteriaceae in a Spanish hospital department from January 2010 to 2014 were reviewed. All isolates with ESBL-positive strains were collected, and isolates received during the first week of each month with ESBL-negative strains from symptomatic patients hospitalized or admitted to the emergency room...
September 11, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28892892/antibiotic-screening-of-urine-culture-for-internal-quality-audit-at-amrita-hospital-kochi
#11
Aswathy Suresh, Anusha Gopinathan, Kavitha R Dinesh, Anil Kumar
INTRODUCTION: Urine antimicrobial activity is a seldom analysed laboratory test which greatly impacts the quantification of urine specimens. Presence of antimicrobial activity in the urine reduces the bacterial load in these specimens. Hence, the chances of erroneously reporting insignificant bacteriuria can be reduced on analysis of the antimicrobial activity in urine. AIM: The aim of the study was to measure the antimicrobial activity of urine samples obtained from patients in a tertiary care hospital...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889140/multiple-bilateral-renal-abscesses-in-a-previously-healthy-young-patient
#12
R Y Tang, B M Cheong
The incidence of renal abscesses is not common. Patients usually have risk factors like diabetes mellitus or an underlying condition which predisposes to urinary tract infections. We report a case of a previously healthy young girl with multiple bilateral renal abscesses. Ultrasonography revealed multiple renal abscesses with a possible differential diagnosis of polycystic kidney disease with infected cysts. No renal calculi were seen. CT-scan of kidneys confirmed the diagnosis. Blood and urine cultures were repeatedly negative...
August 2017: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28885414/urinary-symptoms-and-their-associations-with-urinary-tract-infections-in-urogynecologic-patients
#13
Tanaka J Dune, Travis K Price, Evann E Hilt, Krystal J Thomas-White, Stephanie Kliethermes, Cynthia Brincat, Linda Brubaker, Paul Schreckenberger, Alan J Wolfe, Elizabeth R Mueller
OBJECTIVE: To assess urinary symptoms associated with urinary tract infection (UTI) in a urogynecologic population of women. METHODS: In this cohort study, we enrolled 150 urogynecologic patients who completed the validated UTI Symptom Assessment questionnaire and contributed transurethral catheterized urine samples. The primary measure (UTI diagnosis) was defined in three ways. Self-report (a nonculture-based UTI diagnosis) was defined by a yes or no response to the query "Do you think you have a UTI?" Two culture-based UTI diagnoses also were analyzed: standard urine culture (10 colony-forming units [CFU]/mL or greater) and enhanced quantitative urine culture (10 CFU/mL or greater) of any uropathogen...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28883510/disseminated-tuberculosis-among-hospitalised-hiv-patients-in-south-africa-a-common-condition-that-can-be-rapidly-diagnosed-using-urine-based-assays
#14
Andrew D Kerkhoff, David A Barr, Charlotte Schutz, Rosie Burton, Mark P Nicol, Stephen D Lawn, Graeme Meintjes
HIV-associated disseminated TB (tuberculosis) has been under-recognised and poorly characterised. Blood culture is the gold-standard diagnostic test, but is expensive, slow, and may under-diagnose TB dissemination. In a cohort of hospitalised HIV patients, we aimed to report the prevalence of TB-blood-culture positivity, performance of rapid diagnostics as diagnostic surrogates, and better characterise the clinical phenotype of disseminated TB. HIV-inpatients were systematically investigated using sputum, urine and blood testing...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28882961/efficacy-of-n-acetylcysteine-d-mannose-and-morinda-citrifolia-to-treat-recurrent-cystitis-in-breast-cancer-survivals
#15
Debora Marchiori, Pier Paolo Zanello
BACKGROUND/AIM: Breast cancer survivors in adjuvant therapy, frequently experience the estrogen deficiency with genitourinary symptoms mostly represented by recurrent bacterial cystitis. The objective of the present study was to evaluate the effectiveness of N-acetylcysteine, D-mannose and Morinda citrifolia fruit extract (NDM), when associated to antibiotic therapy, in reducing the persistence of recurrent cystitis in this risk population. PATIENTS AND METHODS: Sixty breast cancer survived women with recurrent cystitis were retrospectively examined...
September 2017: In Vivo
https://www.readbyqxmd.com/read/28872426/enhancing-quality-practice-for-prevention-and-diagnosis-of-urinary-tract-infection-during-inpatient-spinal-cord-rehabilitation
#16
Seyed Mohammad Alavinia, Maryam Omidvar, Farnoosh Farahani, Mark Bayley, Joana Zee, Beverley Catharine Craven
Objectives To reduce the incidence of Urinary Tract Infection (UTI) in subacute SCI individuals admitted for tertiary inpatient rehabilitation. Design A quality improvement team was assembled to improve UTI prevention/diagnosis. To plan data collection, UTI-related factors were mapped in an Ishikawa (fishbone) driver diagram. Data including patient demographics, presence and frequency of signs and/or symptoms of UTI and antibiotic initiation from August to December 2015 were recorded. Sensitivity, Specificity, Positive and Negative Predictive Values (PPV, NPV), and Likelihood Ratios (LR) were calculated for each sign and symptom...
September 5, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28869004/performance-assessment-of-urine-flow-cytometry-ufc-to-screen-urines-to-reflex-to-culture-in-immunocompetent-and-immunosuppressed-hosts
#17
Aleksandra Stefanovic, Diane Roscoe, Romali Ranasinghe, Titus Wong, Elizabeth Bryce, Charlene Porter, Adelina Lim, Jennifer Grant, Karen Ng, Morris Pudek
PURPOSE: Urine flow cytometry (UFC) is an automated method to quantify bacterial and white blood cell (WBC) counts. We aimed to determine whether a threshold for these parameters can be set to use UFC as a sensitive screen to predict which urine samples will subsequently grow in culture. METHODOLOGY: Urines submitted to our microbiology laboratory at a tertiary care centre from 22 July 2015-17 February 2016 underwent UFC (Sysmex UF-1000i) analysis, regular urinalysis and urine culture...
September 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28868229/a-very-unlikely-finding-in-a-male-child-urethral-prolapse
#18
Çiğdem Ulukaya Durakbaşa, Gonca Gercel, Murat Huseyin Mutus, Burhan Aksu, Seyma Ozkanli
Urethral prolapse is a disease of prepubertal black girls and postmenopausal women with an unknown cause. It may be congenital in origin or an acquired condition. It has never been reported in males. We report a 10-year-old Caucasian boy who presented because of recurrent right undescended testis. He had been operated on for bilateral undescended testes 7 years ago in another hospital, and circumcision was done during the same operation. The boy complained of a weak urinary stream during voiding. The physical examination was consistent with recurrent right undescended testis...
January 2017: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/28866698/isolation-by-culture-and-pcr-identification-of-lipl32-gene-of-pathogenic-leptospira-spp-in-wild-rats-of-kuala-lumpur
#19
I Latifah, A Abdul Halim, M S Rahmat, M F Nadia, Z E Ubil, H Asmah, I Shafariatul Akmar, M Picardeau, O Siti Haslina, M A Nasir
BACKGROUND: A study was conducted to confirm the status of rats as the carrier of pathogenic leptospira in Kuala Lumpur, Malaysia. METHOD: A total of 140 urine samples were collected from trapped rats. These samples were cultured in EMJH enriched media and 18 of these samples (12.9%) were found to be positive when observed under x40 by dark field microscope. Genomic DNA was extracted from all the 18 native isolates for PCR. RESULT: All the 18 isolates generated the expected 786 base pair band when the set of primers known to amplify LipL32 gene were utilized...
August 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28865741/long-term-outcomes-of-inappropriate-antibiotic-therapy-for-upper-urinary-tract-infections-caused-by-extended-spectrum-beta-lactamase-producing-enterobacteriaceae-a-retrospective-cohort-study
#20
Inbal Greenhouse, Frida Babushkin, Talya Finn, Zvi Shimoni, Moran Aliman, Ronen Ben-Ami, Regev Cohen
BACKGROUND: To evaluate the short- and long-term outcomes of different antimicrobial treatment options for upper urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae. METHODS: We retrospectively analyzed patients with a first episode of febrile UTI and positive urine culture with ESBL-producing E. coli or K. pneumoniae during 2012-2015. We compared outcomes among patients who received: (1) definitive treatment with a carbapenem (CP), (2) a microbiologically appropriate intravenous non-carbapenem agent (NCA), (3) a non-appropriate antimicrobial (NAA), and (4) an intravenous NAA followed by an oral NCA (NAA-PO)...
July 28, 2017: Diagnostic Microbiology and Infectious Disease
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