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UTI in children

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https://www.readbyqxmd.com/read/28638940/laparoscopic-vesico-ureteral-reimplantation-with-lich-gregoir-approach-in-children-medium-term-results-of-159-renal-units-in-117-children
#1
Victor Soulier, Aure Lien Scalabre, Manuel Lopez, Chi-Ying Li, Sodara Thach, Sophie Vermersch, Franc Ois Varlet
PURPOSE: Vesico-ureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Surgery is an important part of its management. Laparoscopic ureteric reimplantation using the Lich-Gregoir technique is an option for VUR. The aim of this study is to assess short- and medium-term outcomes of this approach. MATERIALS AND METHODS: This is a retrospective study including all children with VUR treated by laparoscopic extravesical ureteral reimplantation with the Lich-Gregoir technique in University Hospital of Saint-Etienne from August 2007 to May 2016...
June 21, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28637056/-urosepsis-in-children
#2
Josef Oswald
Urinary tract infections (UTI) are the most common infectious diseases in children. Urosepsis in childhood, though rare, is the most complicated possible variant. In newborns and infants, unspecific symptoms are a significant barrier to a fast and reliable diagnosis, which is crucial to successful treatment. In addition to urine and laboratory tests as well as non-invasive examinations (ultrasound), there may be an indication for invasive examinations of the kidneys (DMSA scans) in cases of a severe infection...
June 21, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28630017/vesicoureteral-reflux-is-a-phenotype-not-a-disease-a-population-centered-approach-to-pediatric-urinary-tract-infection
#3
REVIEW
Jathin Bandari, Steven G Docimo
We performed a review of the recent literature concerning urinary tract infection (UTI) evaluation and management. In modeling options for management, one overriding conclusion became apparent: in most affected children, the presence of vesicoureteral reflux (VUR) is inconsequential since it has no bearing on optimal management or outcome. In fact, knowing that a child does not have reflux might bias the provider to withhold potentially helpful therapeutic modalities to decrease UTI morbidity, such as antibiotic prophylaxis...
May 22, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28612056/critical-appraisal-of-the-top-down-approach-for-vesicoureteral-reflux
#4
REVIEW
Ahmed Abdelhalim, Antoine E Khoury
Vesicoureteral reflux (VUR) has been linked to recurrent urinary tract infections (UTIs), renal scarring, hypertension, renal insufficiency and end-stage kidney disease. Different imaging strategies have been proposed to approach children presenting with UTI to sort out patients with significant VUR while minimizing patient morbidity, radiation exposure and financial burden. None of these imaging strategies is universally accepted. The"top-down approach" (TDA) aims at restricting the number of voiding cystourethrograms (VCUGs) and its associated morbidity while identifying patients with clinically-significant reflux...
June 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28595971/bladder-debris-on-renal-and-bladder-ultrasound-a-significant-predictor-of-positive-urine-culture
#5
Joseph W McQuaid, Michael P Kurtz, Tanya Logvinenko, Caleb P Nelson
BACKGROUND: Renal and bladder ultrasound (RBUS) is recommended in evaluation of children after an initial, febrile urinary tract infection. Although it is not uncommon to observe debris within the bladder lumen on sonography, the significance of this finding is uncertain. Debris may be interpreted as an indication of ongoing infection, but there have been no studies to date investigating the association of bladder debris with a positive culture. OBJECTIVE: The aim of this study was to evaluate the association of bladder debris noted at the time of RBUS with positive urine culture results obtained from a catheterized specimen, among patients undergoing RBUS and voiding cystourethrogram (VCUG) on the same day...
May 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28592391/long-term-fate-of-the-upper-tracts-following-complete-primary-repair-of-bladder-exstrophy
#6
Jonathan S Ellison, Jennifer Ahn, Margarett Shnorhavorian, Richard Grady, Paul A Merguerian
INTRODUCTION: Complete primary repair of bladder exstrophy (CPRE) is widely used for classic bladder exstrophy (CBE) closure. Long-term renal function with or without dilation in these patients is poorly characterized and may be impacted by bladder storage parameters or recurrent urinary tract infections (UTIs). OBJECTIVE: We sought to assess our long-term experience with CPRE and investigate factors that may influence upper-tract deterioration. STUDY DESIGN: A retrospective review of patients at our institution with CBE undergoing CPRE from 1990 to 2015 was performed...
May 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28587907/-a-family-history-of-renal-lithiasis-in-children-diagnosed-of-urinary-tract-infection-by-escherichia-coli
#7
Víctor García Nieto, Jorge Sotoca Fernández, Monica O'Hagan, Pedro Arango Sancho, Maria Isabel Luis Yanes
INTRODUCTION: Urinary tract infections (UTI) caused by Escherichia coli (E. coli) are common in patients with idiopathic hypercalciuria. As both UTI and hypercalciuria (prelithiasis) have a genetic basis, we wanted to know whether the family history of urolithiasis is more common in children with UTIs caused by E. coli. Secondarily, we wondered if the renal scars are more common in children with prelithiasis. MATERIAL AND METHODS: Ambispective study with collected data from 104 patients (40 male, 64 female) followed after having been diagnosed of UTI by E...
June 3, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28583570/clinical-outcomes-in-pediatric-renal-transplant-recipients-who-received-steroid-based-immunosuppressive-regimen
#8
S Chantarogh, K Tangnararatchakit, W Tirapanich, W Viseshsindh, P Saisawat, K Pirojsakul
BACKGROUND: Although the clinical outcomes of pediatric renal transplantation (RT) in developed countries have improved significantly, the data on clinical outcomes in developing countries are wildly different. METHODS: Children and adolescents who had undergone RT at Ramathibodi Hospital between March 2001 and August 2014 were included. RESULTS: Patients were divided into 2 groups: living related donor (LRD) group (n = 13) and deceased donor (DD) group (n = 30)...
June 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28579135/urinary-tract-infection-after-voiding-cystourethrogram
#9
E K Johnson, N R Malhotra, R Shannon, D L Jacobson, J Green, C K Rigsby, J L Holl, E Y Cheng
BACKGROUND: Reported rates of post-procedural urinary tract infection (ppUTI) after voiding cystourethrogram (VCUG) are highly variable (0-42%). OBJECTIVE: This study aimed to determine the risk of ppUTI after cystogram, and evaluate predictors of ppUTI. STUDY DESIGN: A retrospective cohort study of children undergoing VCUG or radionuclide cystogram (henceforth 'cystogram') was conducted. Children with neurogenic bladder who underwent cystogram in the operating room and without follow-up at the study institution were excluded...
May 25, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28579134/the-impact-of-obesity-on-pediatric-inpatients-with-urinary-tract-infections-in-the-united-states
#10
Yusuke Okubo, Atsuhiko Handa
INTRODUCTION: Urinary tract infections (UTI) are common infectious disorders, and obesity is an increasing public health problem worldwide. Several studies have suggested that childhood obesity may be associated with the development of UTI. However, the potential effects of obesity on the clinical outcomes of UTI in children remain unknown. MATERIALS AND METHODS: Hospital discharge records for patients aged 18 years or younger with a diagnosis of UTI were extracted from the 2012 Kids' Inpatient Database...
May 24, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28557737/antibiotic-prophylaxis-for-urinary-tract-infection-related-renal-scarring-a-systematic-review
#11
REVIEW
Ian K Hewitt, Marco Pennesi, William Morello, Luca Ronfani, Giovanni Montini
CONTEXT: Acute pyelonephritis may result in renal scarring. Recent prospective studies have shown a small benefit of antibiotic prophylaxis in preventing symptomatic and febrile urinary tract infections (UTIs), while being underpowered to detect any influence in prevention of renal damage. OBJECTIVES: Review of the literature and a meta-analysis to evaluate the effect of antibiotic prophylaxis on UTI-related renal scarring. DATA SOURCES: Medline, Embase, and Cochrane Controlled Trials Register electronic databases were searched for studies published in any language and bibliographies of identified prospective randomized controlled trials (RCTs) performed and published between 1946 and August 2016...
May 2017: Pediatrics
https://www.readbyqxmd.com/read/28555450/usefulness-of-parametric-renal-clearance-images-in-the-assessment-of-basic-risk-factors-for-renalnal-clearance-images-in-the-assessment-of-basic-risk-factors-for-renal-scarring-in-children-with-recurrent-urinary-tract-infections
#12
Ewa Pietrzak-Stelasiak, Małgorzata Bieńkiewicz, Wojciech Woźnicki, Krystyna Bubińska, Magdalena Kowalewska-Pietrzak, Anna Płachcińska, Jacek Kuśmierek
BACKGROUND: Clinically confirmed incidents of acute pyelonephritis (APN) following recurrent infections of urinary tract (UTI) form basic risk factors for renal scarring in children. Vesico-uretheral reflux (VUR) of higher grade is additional risk factor for this scarring. Opinions on diagnostic value of summed sequential images of renal uptake phase (SUM) of dynamic renal scintigraphy in detection of renal scars are diverse. However, several publications point to higher diagnostic efficacy of clearance parametric images (PAR) generated from this study...
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28533635/tc-99m-ethylenedicysteine-and-tc-99m-dimercaptosuccinic-acid-scintigraphy-comparison-of-the-two-for-detection-of-scarring-and-differential-cortical-function
#13
Anitha Dharmalingam, Shwetal U Pawar, Sandesh V Parelkar, Suruchi S Shetye, Mangala K Ghorpade, Gundu H Tilve
CONTEXT: The differential cortical function obtained by Tc-99m EC is comparable to that of Tc-99m DMSA. However, identification of scars on Tc-99m EC images needs to be studied. AIMS: The aim of the study is to evaluate role of Tc-99m EC for detection of scarring and differential cortical function by comparing with Tc-99m DMSA. SETTINGS AND DESIGN: Prospective observational study of recurrent UTI; minimum 6 weeks after acute episode; when urine examination is negative for pus cells...
April 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28532765/prenatal-complicated-duplex-collecting-system-and-ureterocele-important-risk-factors-for-urinary-tract-infection
#14
Sofia Visuri, Timo Jahnukainen, Seppo Taskinen
PURPOSE: To evaluate the risk of urinary tract infections (UTIs) in infants with prenatally detected complicated duplex collecting system (CDS) or ureterocele. MATERIALS AND METHODS: All patients with prenatally detected CDS (n=34) or single system ureterocele (n=7) who were admitted to our institution between 2003 and 2013 were enrolled in this retrospective analysis. Duplex collecting systems with ureterocele (n=13), vesicoureteral reflux (VUR) (n=20) or nonrefluxing megaureter without ureterocele (n=7) were determined as complicated...
May 11, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28528936/efficacy-of-non-carbapenem-antibiotics-for-pediatric-patients-with-first-febrile-urinary-tract-infection-due-to-extended-spectrum-beta-lactamase-producing-escherichia-coli
#15
Yoshifusa Abe, Işil Inan-Erdogan, Kunihiko Fukuchi, Hitomi Wakabayashi, Yasuha Ogawa, Satoshi Hibino, Shunsuke Sakurai, Kazuhiko Matsuhashi, Yoshitaka Watanabe, Kaori Hashimoto, Kazuhisa Ugajin, Kazuo Itabashi
Although carbapenem is the recommended for urinary tract infection (UTI) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms, non-carbapenems have been reported to be effective for adult patients with UTI caused by ESBL-producing organisms. The purpose of this study was to evaluate the efficacy of non-carbapenems for pediatric patients with UTI due to ESBL-producing Escherichia coli (E. coli) based on the microbiologic and clinical outcomes. Fifteen children, who were treated for first febrile UTI caused by ESBL-producing E...
May 18, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28507631/voiding-urosonography-with-second-generation-ultrasound-contrast-agent-for-diagnosis-of-vesicoureteric-reflux-first-local-pilot-study
#16
Dafina Kuzmanovska, Aleksandar Risteski, Margarita Kambovska, Tase Trpcevski, Emilija Sahpazova, Mile Petrovski
BACKGROUND: Vesicoureteric reflux (VUR) is an important association of paediatric urinary tract infection (UTI) found in 30-50% of all children presenting with first UTI. Contrast-enhanced voiding ultrasonography (ceVUS) has become an important radiation-free method for VUR detection in children. Its sensitivity in detecting VUR has greatly improved due to the development of the contrast-specific ultrasound techniques and the introduction of the second-generation ultrasound contrast agent, superseding the diagnostic accuracy of standard radiological procedures...
April 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28505288/effect-of-different-antibiotics-on-biofilm-produced-by-uropathogenic-escherichia-coli-isolated-from-children-with-urinary-tract-infection
#17
María José González, Luciana Robino, Victoria Iribarnegaray, Pablo Zunino, Paola Scavone
Recurrent urinary tract infections (UTIs) occur frequently in children and women. Intracellular bacterial communities (IBCs) and biofilm formation by Escherichia coli are risk factors for recurrence. The aim of this study was to evaluate the effect of different antibiotics on biofilms by E. coli strains isolated from children with UTI and to correlate virulence factors and IBCs with biofilm formation. A total of 116 E. coli strains were tested for biofilm formation using the crystal violet microplate technique...
June 1, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28497052/etiological-and-resistance-profile-of-bacteria-involved-in-urinary-tract-infections-in-young-children
#18
Antonio Sorlózano-Puerto, José María Gómez-Luque, Juan de Dios Luna-Del-Castillo, José María Navarro-Marí, José Gutiérrez-Fernández
Background. The objective of this study was to identify the bacteria most frequently responsible for urinary tract infection (UTI) in the population of under-2-year-olds in our geographic area and to evaluate the activity of antibiotics widely used for UTI treatment during a 4-year study period. Materials and Methods. A retrospective analysis was conducted of data on the identification and susceptibility of microorganisms isolated in urine samples from children under 2 years of age. Results. A total of 1,045 uropathogens were isolated...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28488726/prediction-of-renal-cortical-defect-and-scar-using-neutrophil-to-lymphocyte-ratio-in-children-with-febrile-urinary-tract-infection
#19
Jeong Won Lee, Joon Soo Park, Kyeong Bae Park, Gyeong Hee Yoo, Seung Soo Kim, Sang Mi Lee
AIM: This study is aimed to evaluate the predictive value of the neutrophil-to-lymphocyte ratio (NLR) for cortical defect on initial and follow-up Tc-99m dimercaptosuccinic acid (DMSA) scan in children with the first febrile urinary tract infection (UTI). METHODS: We retrospectively enrolled 179 children with the first febrile UTI who underwent DMSA scan and laboratory tests. In patients with abnormal DMSA scan findings, follow-up DMSA scan was performed at least 6 months after the initial scan...
May 10, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/28487733/do-routine-preoperative-and-intraoperative-urine-cultures-benefit-pediatric-vesicoureteral-reflux-surgery
#20
Daniel R Hettel, Bradley C Gill, Audrey C Rhee
Objective. To determine if routine preoperative and intraoperative urine cultures (UCx) are necessary in pediatric vesicoureteral (VUR) reflux surgery by identifying their association with each other, preoperative symptoms, and surgical outcomes. Materials and Methods. A retrospective review of patients undergoing ureteral reimplant(s) for primary VUR at a tertiary academic medical center between years 2000 and 2014 was done. Preoperative UCx were defined as those within 30 days before surgery. A positive culture was defined as >50,000 colony forming units of a single organism...
2017: Advances in Urology
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