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https://www.readbyqxmd.com/read/27894763/extended-spectrum-beta-lactamase-esbl-producing-bacteria-urinary-tract-infections-and-complex-pediatric-urology
#1
Ruth Wragg, Anna Harris, Mitul Patel, Andrew Robb, Harish Chandran, Liam McCarthy
AIM OF THE STUDY: Extended spectrum beta lactamase (ESBL) producing bacteria are resistant to most beta-lactam antibiotics including third-generation cephalosporins, quinolones and aminoglycosides. This resistance is plasmid-borne and can spread between species. Management of ESBL is challenging in children with recurrent urinary tract infections (UTIs) and complex urological abnormalities. We aim to quantify the risk in children and specifically in urological patients. METHODS: Retrospective review of a microbiology database (April 2014 to November 2015)...
November 13, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27891664/healthcare-costs-doubled-when-children-had-urinary-tract-infections-caused-by-extended-spectrum-%C3%AE-lactamase-producing-bacteria
#2
Oona Nieminen, Matti Korppi, Merja Helminen
AIM: The impact of the emergence of antimicrobial resistant organisms has rarely been studied in children, including the healthcare costs of urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria. We evaluated the effect of ESBL on UTI healthcare costs and risk factors for paediatric UTIs. METHODS: This retrospective case-control study covered 2005-2014 and focused on children below 16 years of age treated in a University hospital: 22 children with UTIs caused by ESBL-producing bacteria and 56 ESBL-negative UTI controls...
November 7, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27891414/paediatric-urinary-tract-infection-a-hospital-based-experience
#3
Khursheed Ahmed Wani, Mohd Ashraf, Javaid Ahmed Bhat, Nazir Ahmed Parry, Lubna Shaheen, Sartaj Ali Bhat
INTRODUCTION: Paediatric Urinary Tract Infection (UTI) is one of the commonly encountered entities by paediatricians. Studies have shown easy vulnerability of paediatric urinary tract in any acute febrile illness and a miss in diagnosis could have long term consequences like renal scaring with its adverse effects. Bearing these evidence based preludes in view we designed our study to know the prevalence of UTI in Kashmir province. AIM: Aim of the present study was to know the prevalence of UTI in febrile children and to know the sensitivity of different imaging modalities like Renal and Urinary Bladder Ultrasonography (RUS), Voiding Cystourethrography (VCUG) and Dimercaptosuccinic Acid (DMSA) scan in diagnosing UTI...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890813/international-travel-is-a-risk-factor-for-extended-spectrum-%C3%AE-lactamase-producing-enterobacteriaceae-acquisition-in-children-a-single-center-case-case-control-study-in-an-urban-u-s-hospital
#4
Jonathan P Strysko, Vidya Mony, Jeremiah Cleveland, Hanna Siddiqui, Peter Homel, Christina Gagliardo
BACKGROUND: Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL) infections are increasing in both adults and children. The aim of this study was to describe the epidemiology of children with ESBL in an urban and ethnically-diverse population, to determine what proportion of these infections were community-onset, and to identify risk factors predisposing children to ESBL acquisition. METHODS: A case-case-control study of children aged 0-18 years was conducted from 2012-2014...
November 24, 2016: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/27889492/surgical-complications-following-early-genitourinary-reconstructive-surgery-for-congenital-adrenal-hyperplasia-interim-analysis-at-6-years
#5
Pankaj Dangle, Andy Lee, Rajeev Chaudhry, Francis X Schneck
OBJECTIVE: To review the intermediate to long-term surgical complications following feminizing reconstructive surgery for patients with congenital adrenal hyperplasia (CAH), at a single tertiary center. Genitourinary reconstructive surgery is pivotal for favorable cosmetic and functional outcome for patients with CAH. MATERIAL AND METHODS: We conducted a retrospective review identifying 26 patients from April 2003 to April 2015 who underwent genitourinary reconstructive surgeries...
November 23, 2016: Urology
https://www.readbyqxmd.com/read/27889221/the-swedish-infant-high-grade-reflux-trial-study-presentation-and-vesicoureteral-reflux-outcome
#6
Josefin Nordenström, Gundela Holmdahl, Per Brandström, Rune Sixt, Eira Stokland, Ulla Sillén, Sofia Sjöström
INTRODUCTION: High-grade vesicoureteral reflux (VUR) in infants is associated with congenital renal abnormalities, recurrent UTI, and bladder dysfunction. Endoscopic treatment (ET) is a well-established method in children with low to moderate reflux grades, but there is a lack of randomised controlled trials regarding the use of ET versus continuous antibiotic prophylaxis in infants with high-grade VUR. OBJECTIVE: This study aimed to determine whether high-grade VUR in infants can be treated with endoscopic injection and whether ET is superior to antibiotic prophylaxis in the treatment of VUR...
October 24, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27888411/to-screen-or-not-to-screen-for-vesicoureteral-reflux-in-children-with-ureteropelvic-junction-obstruction-a-systematic-review
#7
REVIEW
Marcus Weitz, Maria Schmidt
: Ureteropelvic junction obstruction (UPJO) and vesicoureteral reflux (VUR) are the most common uropathies. The co-occurrence of both anomalies has led to the practice of screening for VUR in children with UPJO to prevent deterioration of kidney function due to renal scarring following urinary tract infections (UTIs). We determined the prevalence of VUR in children with UPJO for a critical assessment of VUR screening by voiding cystourethrography (VCUG). A systematic search strategy in MEDLINE, EMBASE, and CENTRAL was carried out for all articles that included VCUG, and renal scintigraphy or any other appropriate imaging technique for the diagnosis of UPJO...
November 25, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27887911/does-perception-of-catheterization-limit-its-use-in-pediatric-uti
#8
Rachel E Selekman, Melissa T Sanford, Lauren N Ko, I Elaine Allen, Hillary L Copp
INTRODUCTION: Urinary tract infections (UTIs) affect 3-8% of febrile children annually, but correctly diagnosing UTI in young children can present a challenge. Diagnosis requires a non-contaminated urine sample, which requires catheterization or suprapubic aspiration in infants and young children that have not completed toilet training. To improve adherence to these guidelines, it is critical to understand the barriers to urine testing and catheterization. OBJECTIVE: The purpose of this study was to investigate parental perception of pediatric UTI evaluation to better understand factors that impede urine testing prior to treatment of suspected UTI...
October 20, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27882009/functional-and-structural-abnormalities-of-the-kidney-and-urinary-tract-in-severely-malnourished-children-a-hospital-based-study
#9
Misbah Anjum, Khemchand N Moorani, Ifra Sameen, Muhammad Ayaz Mustufa, Shazia Kulsoom
OBJECTIVES: The association of malnutrition and systemic diseases like chronic kidney disease (CKD) is well known. Various urinary tract abnormalities may be associated with malnutrition. So objective of current study was to determine the frequency of functional and structural urinary tract abnormalities in severely malnourished children admitted in Nutritional Rehabilitation Unit (NRU) of a tertiary care facility, Karachi. METHODS: This descriptive cases series of 78 children was conducted in NRU from October 2014 - March 2015...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27878110/discontinuation-of-antimicrobial-prophylaxis-ap-in-children-with-spina-bifida-a-case-series-analysis
#10
Kevin G Couloures, Michael Anderson, Michael Machiorlatti, Olivera Marsenic, Lawrence Opas
BACKGROUND: Spina bifida increases the risk for urinary tract infections (UTI). Antimicrobial prophylaxis (AP) reduces symptomatic UTI's but selects resistant organisms. Measures to ensure regular and complete emptying of the bladder combined with treatment of constipation reduce the risk for UTI. OBJECTIVES: Demonstrate that close adherence to a catheterization regimen in children with spina bifida (Selective Treatment - ST) reduces the need for antimicrobial prophylaxis...
September 2016: Nephro-urology Monthly
https://www.readbyqxmd.com/read/27866177/cranberries-for-preventing-recurrent-urinary-tract-infections-in-uncircumcised-boys
#11
Kong-Sang Wan, Chih-Kuang Liu, Wen-Kai Lee, Ming-Chung Ko, Che-Sheng Huang
Background • Highly concentrated cranberry juice has long been considered to have protective properties against urinary tract infections (UTIs), on the basis of its content of cranberry proanthocyanidins, with A-type interflavan bonds. Objective • This study intended to evaluate the benefits of a highly concentrated cranberry juice for the prevention of repeated episodes of UTI in uncircumcised boys. Design • The study was a randomized, controlled trial. Setting • The study took place at Taipei City Hospital, Renai and Zhongxing Branches (Taipei City, Taiwan)...
November 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27848095/endemic-bladder-calculi-in-children
#12
Neveen A Soliman, S Adibul Hasan Rizvi
Urinary calculi are being recognized more frequently in children and the urinary bladder is the most common site for stone formation in the lower urinary tract. Bladder calculi are grouped into three basic categories: primary idiopathic/endemic, secondary, and migrant. The incidence of vesical calculi has declined significantly in the last 70 years in developed nations owing to improvements in nutrition and socioeconomic conditions, but it is still high in developing nations. Primary idiopathic/endemic bladder calculi typically occur in children, in the absence of urinary tract infection (UTI), urinary stasis, or foreign body, and diet lacking in animal proteins is the major contributor factor...
November 15, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27843222/prolapsing-cystitis-cystica-causing-bladder-outlet-obstruction-an-unusual-complication
#13
Pankaj Halder, Kartik Chandra Mandal, Sumedha Mukherjee
Cystitis cystica (CC) is aproliferative disorder of bladder urothelium and usually subsides with medical therapy. However, this is not true for severe CC where surgical intervention is required to control breakthrough urinary tract infection (UTI). It may be mistaken as bladder neoplasm or posterior urethral valve, especially in children. Here, we report a case of CC in a 2-year-old boy where we had to excise the large pedunculated intravesical lesion to control breakthrough UTI and ongoing renal damage.
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27836442/intravesical-ureteric-reimplantation-for-primary-obstructed-megaureter-in-infants-under-1-year-of-age
#14
Emily Jude, Aniruddh Deshpande, Andrew Barker, Japinder Khosa, Naeem Samnakay
PURPOSE: This study aimed to assess the outcome of intravesical ureteric reimplantation for primary obstructed megaureter (POM) performed in infants under 1 year of age. MATERIALS AND METHODS: A retrospective cohort study was carried out of all infants undergoing intravesical ureteric reimplantation surgery for POM at two pediatric centers in the 12 years between 2003 and 2014. Outcomes were compared with those of children aged over 1 year undergoing intravesical reimplantation for POM during this period...
October 24, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27834092/urinary-tract-infection-in-childhood-and-inflammatory-markers
#15
S Tamgumus, J Geoghan, D Coghlan, M Nadeem
Acute urinary tract infections are common in children. Our aim was to establish whether peripheral blood tests correlate with urinary culture. We also examined the relationship between peripheral blood results and the length of stay (LOS) in children and adolescents with UTI. We studied 135 patients admitted with UTI, mean (SD) age 3.0 (4.1) years. Of these 135 patients, 16 (11.9%) had combined normal serum WCC, normal neutrophil count and CRP < 5 mg/L. In this group of patients, there was no significant association between LOS and serum WCC, serum neutrophil values, E...
August 8, 2016: Irish Medical Journal
https://www.readbyqxmd.com/read/27833443/urine-interleukin-6-interleukin-8-and-transforming-growth-factor-%C3%AE-1-in-infants-with-urinary-tract-infection-and-asymptomatic-bacteriuria
#16
Grażyna Krzemień, Agnieszka Szmigielska, Agnieszka Turczyn, Małgorzata Pańczyk-Tomaszewska
INTRODUCTION: Urinary tract infection (UTI) occurs in 1.1% of girls and 1.4% of boys during the first year of life. Asymptomatic bacteriuria (ABU) is usually detected incidentally in 0.9% of girls and 2.5% of boys at this age. The aim of the study was to assess the usefulness of measurement of pro-inflammatory urine interleukin (IL)-6 and IL-8 concentrations and anti-inflammatory transforming growth factor β1 (TGF-β1) level in infants with febrile UTI, non-febrile UTI and ABU. MATERIAL AND METHODS: A total of 35 children, mean age 6...
2016: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/27821091/model-estimates-of-the-burden-of-outpatient-visits-attributable-to-influenza-in-the-united-states
#17
Gonçalo Matias, François Haguinet, Roger L Lustig, Laurel Edelman, Gerardo Chowell, Robert J Taylor
BACKGROUND: Although many studies have modelled the national burdens of hospitalizations and deaths due to influenza, few studies have considered the outpatient burden. To fill this gap for the United States (US), we applied traditional statistical modelling approaches to time series derived from large medical claims databases held in the private sector. METHODS: We accessed ICD-9-coded office visit data extracted from Truven Health Analytics' MarketScan Commercial database covering about one third of the US population <65 years during 2001-2009, and Medicare Supplemental data covering about one fifth of US seniors 65+ during 2006-2009...
November 7, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27819162/evaluation-of-abnormal-radiological-findings-in-children-aged-2-to-36-months-followed-by-recurrent-urinary-tract-infection-a-retrospective-study
#18
Cinar Ozen, Pelin Ertan, Feray Aras, Gul Gumuser, Mine Ozkol, Gonul Horasan Dinc
Our aim is to determine the rational usage of imaging techniques in order to prevent or minimize permanent renal damage in recurrent urinary tract infections (UTIs). This study was enrolled children aged between 2 and 36 months, following-up with the diagnosis of recurrent UTI. All children had ultrasonography (USG) and dimercaptosuccinic acid scanning, 39 of them had underwent on voiding cystourethrography. There were 133 children (87 girls, 46 boys) with the mean age of 32.82 ± 38.10 months included into the study...
November 6, 2016: Renal Failure
https://www.readbyqxmd.com/read/27801524/detection-of-pct-and-urinary-%C3%AE-2-mg-enhances-the-accuracy-for-localization-diagnosing-pediatric-urinary-tract-infection
#19
Jian Fang, Jiangwei Luan, Gaohong Zhu, Chang Qi, Dandan Wang
OBJECTIVE: The purpose of this article was to investigate whether the combination of urinary beta 2 microglobulin (urinary β2 -MG) and procalcitonin (PCT) diagnosis could enhance the localization diagnostic precision of pediatric urinary tract infection comparing with single diagnosis. METHODS: A study was conducted in the Nephrology Department of Wuhan women and children's health care centre. This study incorporated 85 participants, including 35 children who were diagnosed as upper urinary tract infection (UUTI) with the symptom of fever and 50 children who conducted lower urinary tract infection (LUTI)...
November 1, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27785466/taking-the-sting-out-of-ureteral-obstruction
#20
Jack Crozier, Ivan Aw, Philip Huang Min Tan, David Clarke
Vesicoureteral reflux (VUR) is diagnosed in ∼1% of children. The main goal of treatment is preservation of renal function by preventing recurrent urinary tract infection (UTI) refractory to antibiotic therapy. Surgical treatment options include endoscopic injection or ureteral reimplantation. Subureteral Teflon (polytetrafluoroethylene) injection (STING) is an endoscopic treatment option no longer in common practice. Use of Teflon is no longer advised because of a number of documented complications secondary to local and distant migration of injected material...
2016: Journal of Endourology Case Reports
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