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https://www.readbyqxmd.com/read/28221158/-urinary-lithiasis-treatment-by-laparoscopy-combined-techniques
#1
Inmaculada Fernández González, Ricardo Brime Menendez, Guillermo Celada Luis, Marco Antonio Acosta Reveles, Eduardo Mariano Albers Acosta, Pilar Mejía Celemin, Luis Alberto San José Manso, Javier Casado Varela
Over the last 30 years, the treatment of urinary lithiasis has changed dramatically. With the advent of extracorporeal lithotripsy and the advances on ureterorenoscopy and percutaneous nephrolithotomy, the need to turn to open and laparoscopic/robotic surgery has diminished. The objective of this article is to review the different indications for open and/or laparoscopic treatment of urinary lithiasis, to achieve its complete elimination with the less invasive possible means and trying to minimize the number of secondary procedures as well as complications...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28221036/review-of-the-assignment-of-the-absolute-configuration-by-nmr-using-chiral-derivatizing-agents-a-practical-guide-the-assignment-of-the-absolute-configuration-by-nmr-using-chiral-derivatizing-agents-a-practical-guide-by-jos%C3%A3-m-seco-emilio-qui%C3%A3-o%C3%A3-and-ricardo
#2
https://www.readbyqxmd.com/read/28220116/cpg-odn-shapes-alum-adjuvant-activity-signaling-via-myd88-and-il-10
#3
Luciana Mirotti, Ricardo Wesley Alberca Custódio, Eliane Gomes, Florencia Rammauro, Eliseu Frank de Araujo, Vera Lucia Garcia Calich, Momtchilo Russo
Aluminum-containing adjuvants usually referred as Alum are considered as T helper type-2 (Th2) adjuvants, while agonists of toll-like receptors (TLRs) are viewed as adjuvants that favor Th1/Th17 immunity. Alum has been used in numerous vaccine formulations; however, its undesired pro-Th2 adjuvant activity constitutes a caveat for Alum-based vaccines. Combining Alum with TLR-dependent, pro-Th1/Th17 adjuvants might dampen the pro-Th2 activity and improve the effectiveness of vaccine formulations. Here, using the ovalbumin (OVA) model of allergic lung inflammation, we found that sensitization with the synthetic TLR9 agonist, which is composed of oligodeoxynucleotides containing CpG motifs adsorbed to Alum, inhibited the development of OVA-induced lung allergic Th2 responses without shifting toward a Th1 pattern...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28220071/efficient-computation-of-functional-brain-networks-toward-real-time-functional-connectivity
#4
Juan García-Prieto, Ricardo Bajo, Ernesto Pereda
Functional Connectivity has demonstrated to be a key concept for unraveling how the brain balances functional segregation and integration properties while processing information. This work presents a set of open-source tools that significantly increase computational efficiency of some well-known connectivity indices and Graph-Theory measures. PLV, PLI, ImC, and wPLI as Phase Synchronization measures, Mutual Information as an information theory based measure, and Generalized Synchronization indices are computed much more efficiently than prior open-source available implementations...
2017: Frontiers in Neuroinformatics
https://www.readbyqxmd.com/read/28220063/vibrotactile-discrimination-training-affects-brain-connectivity-in-profoundly-deaf-individuals
#5
Andrés A González-Garrido, Vanessa D Ruiz-Stovel, Fabiola R Gómez-Velázquez, Hugo Vélez-Pérez, Rebeca Romo-Vázquez, Ricardo A Salido-Ruiz, Aurora Espinoza-Valdez, Luis R Campos
Early auditory deprivation has serious neurodevelopmental and cognitive repercussions largely derived from impoverished and delayed language acquisition. These conditions may be associated with early changes in brain connectivity. Vibrotactile stimulation is a sensory substitution method that allows perception and discrimination of sound, and even speech. To clarify the efficacy of this approach, a vibrotactile oddball task with 700 and 900 Hz pure-tones as stimuli [counterbalanced as target (T: 20% of the total) and non-target (NT: 80%)] with simultaneous EEG recording was performed by 14 profoundly deaf and 14 normal-hearing (NH) subjects, before and after a short training period (five 1-h sessions; in 2...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219769/epitranscriptomic-regulation-of-viral-replication
#6
REVIEW
Camila Pereira-Montecinos, Fernando Valiente-Echeverría, Ricardo Soto-Rifo
RNA plays central roles in biology and novel functions and regulation mechanisms are constantly emerging. To accomplish some of their functions within the cell, RNA molecules undergo hundreds of chemical modifications from which N6-methyladenosine (m(6)A), inosine (I), pseudouridine (ψ) and 5-methylcytosine (5mC) have been described in eukaryotic mRNA. Interestingly, the m(6)A modification was shown to be reversible, adding novel layers of regulation of gene expression through what is now recognized as epitranscriptomics...
February 17, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28219403/the-kiva-antibullying-program-in-primary-schools-in-chile-with-and-without-the-digital-game-component-study-protocol-for-a-randomized-controlled-trial
#7
Jorge Gaete, Daniela Valenzuela, Cristian Rojas-Barahona, Eduardo Valenzuela, Ricardo Araya, Christina Salmivalli
BACKGROUND: Bullying is a major problem worldwide and Chile is no exception. Bullying is defined as a systematic aggressive behavior against a victim who cannot defend him or herself. Victims suffer social isolation and psychological maladjustment, while bullies have a higher risk for conduct problems and substance use disorders. These problems appear to last over time. The KiVa antibullying program has been evaluated in Finland and other European countries, showing preventive effects on victimization and self-reported bullying...
February 20, 2017: Trials
https://www.readbyqxmd.com/read/28218975/stacking-transgenic-event-das-%C3%A3-15%C3%A3-7-1-alters-maize-composition-less-than-traditional-breeding
#8
Rod A Herman, Brandon J Fast, Peter N Scherer, Alyssa M Brune, Denise T de Cerqueira, Barry W Schafer, Ricardo D Ekmay, George G Harrigan, Greg A Bradfisch
The impact of crossing ("stacking") genetically modified (GM) events on maize-grain biochemical composition was compared with the impact of generating non-GM hybrids. The compositional similarity of seven GM stacks containing event DAS-Ø15Ø7-1 and their matched non-GM near-isogenic hybrids (iso-hybrids) was compared with the compositional similarity of concurrently grown non-GM hybrids and these same iso-hybrids. Scatter plots were used to visualize comparisons among hybrids and a coefficient of identity (percent of variation explained by line of identity) was calculated to quantify the relationships within analyte profiles...
February 20, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28217912/cold-adaptation-of-the-antarctic-haloarchaea-halohasta-litchfieldiae-and-halorubrum-lacusprofundi
#9
Timothy J Williams, Yan Liao, Jun Ye, Rhiannon P Kuchel, Anne Poljak, Mark J Raftery, Ricardo Cavicchioli
Halohasta litchfieldiae represents ∼ 44% and Halorubrum lacusprofundi ∼ 10% of the hypersaline, perennially cold (≥ -20°C) Deep Lake community in Antarctica. We used proteomics and microscopy to define physiological responses of these haloarchaea to growth at high (30°C) and low (10 and 4°C) temperatures. The proteomic data indicate that both species responded to low temperature by modifying their cell envelope including protein N-glycosylation, maintaining osmotic balance and translation initiation, and modifying RNA turnover and tRNA modification...
February 20, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28216274/micro-computed-tomography-assessment-of-dentinal-micro-cracks-after-root-canal-preparation-with-trushape-and-self-adjusting-file-systems
#10
Mario Luis Zuolo, Gustavo De-Deus, Felipe Gonçalves Belladonna, Emmanuel João Nogueira Leal da Silva, Ricardo Tadeu Lopes, Erick Miranda Souza, Marco Aurélio Versiani, Alexandre Augusto Zaia
INTRODUCTION: The aim of the present study was to evaluate the percentage frequency of dentinal micro-cracks observed after root canal preparation with TRUShape and Self-Adjusting File (SAF) systems by means of micro-computed tomography imaging analysis. A conventional full-sequence rotary system (BioRace) and a single-file reciprocation system (Reciproc) were used as reference techniques for comparison because of their known assertive cutting efficiency. METHODS: Forty anatomically matched mandibular incisors were selected, scanned at a resolution of 14...
February 16, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28216254/cardiac-sarcoidosis-diagnostic-challenges-due-to-unusual-clinical-presentation
#11
Karolis Kluonaitis, Sigita Glaveckaite, Giedre Balciunaite, Austeja Juskaite, Darius Palionis, Nomeda Valeviciene, Ugnius Mickys, Rimgaudas Katkus, Ricardo Fontes-Carvalho, Jelena Celutkiene
No abstract text is available yet for this article.
February 16, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/28216169/cytogenotoxicological-defense-of-retinyl-palmitate-in-the-front-damage-of-antineoplastics
#12
Ricardo Melo de Carvalho, Rai Pablo de Sousa Aguiar, Muhammad Torequl Islam, Marcus Vinicius Oliveira Barros de Alencar, Ana Maria Oliveira Ferreira da Mata, Antonio Lima Braga, Josemar José da Silva Júnior, Leonardo da Rocha Sousa, Rosália Maria Tôrres de Lima, Márcia Fernanda Correia Jardim Paz, João Marcelo de Castro E Sousa, Ana Amélia de Carvalho Melo-Cavalcante
Cancer, the multifactorial pathology and to date is the most lethal causes of death in the world. Cyclophosphamide (CPA) and doxorubicin (DOX) are the individually or combindly used two anticancer drugs. The antineoplastic drugs-mediated genetic instability can be overcome by using antioxidants. The study evaluated the cytogenotoxic modulatory potentials of retinyl palmitate (RP) caused by CPA and DOX in Swiss mice. For this, adult Mus musculus of either sex were divided equally regarding to the gender. Toxicogenetic effects were induced by the intraperitoneal (i...
February 16, 2017: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/28216048/chloroquine-blocks-the-kir4-1-channels-by-an-open-pore-blocking-mechanism
#13
Leticia G Marmolejo-Murillo, Iván A Aréchiga-Figueroa, Eloy G Moreno-Galindo, Ricardo A Navarro-Polanco, Aldo A Rodríguez-Menchaca, Meng Cui, José A Sánchez-Chapula, Tania Ferrer
Kir4.1 channels have been implicated in various physiological processes, mainly in the K(+) homeostasis of the central nervous system and in the control of glial function and neuronal excitability. Even though, pharmacological research of these channels is very limited. Chloroquine (CQ) is an amino quinolone derivative known to inhibit Kir2.1 and Kir6.2 channels with different action mechanism and binding site. Here, we employed patch-clamp methods, mutagenesis analysis, and molecular modeling to characterize the molecular pharmacology of Kir4...
February 16, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28216029/ecophysiological-responses-of-juvenile-seabass-dicentrarchus-labrax-exposed-to-increased-temperature-and-dietary-methylmercury
#14
Ana Luísa Maulvault, Vera Barbosa, Ricardo Alves, Ana Custódio, Patrícia Anacleto, Tiago Repolho, Pedro Pousão Ferreira, Rui Rosa, António Marques, Mário Diniz
The ecotoxicological effects of methylmercury (MeHg) exposure have been intensively described in literature. Yet, it is still unclear how marine biota will respond to the presence of MeHg under climate change, namely ocean warming. The present study aimed to investigate, for the first time, fish condition [Fulton's K index (K), hepatosomatic index (HIS) and brain-to-body mass ratio (BB-ratio)] and several stress-related responses in an ecologically and commercially important fish species (Dicentrachus labrax) exposed for 28days to dietary MeHg (8...
February 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28216018/prospective-randomised-controlled-study-evaluating-early-modification-of-oral-microbiota-following-admission-to-the-intensive-care-unit-and-oral-hygiene-with-chlorhexidine
#15
Felipe Francisco Tuon, Oleg Gavrilko, Saulo de Almeida, Eigi Ricardo Sumi, Thiago Alberto, Jaime Luis Rocha, Edvaldo Antonio Rosa
OBJECTIVES: Chlorhexidine (CHX) is the most commonly used oral hygiene product for the prevention of ventilator-associated pneumonia (VAP) in patients undergoing mechanical ventilation (MV). The change in dental plaque (DP) microbiota following CHX use in patients under MV has not been described previously. The aim of this study was to evaluate the incidence of pathogenic bacteria associated with VAP and the coverage of DP within the oral cavity in patients administered CHX. METHODS: This was a prospective, randomised, controlled, double-blind study in patients (n=16) under MV who were mouth-rinsed with either CHX or placebo...
February 18, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28215848/erratum-to-the-natural-history-of-renal-function-after-surgical-management-of-renal-cell-carcinoma-results-from-the-canadian-kidney-cancer-information-system-urol-oncol-34-11-2016-486-e1-486-e7
#16
Ross Mason, Anil Kapoor, Zhihui Liu, Olli Saarela, Simon Tanguay, Michael Jewett, Antonio Finelli, Louis Lacombe, Jun Kawakami, Ronald Moore, Christopher Morash, Peter Black, Ricardo A Rendon
No abstract text is available yet for this article.
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28215686/transrectal-doppler-sonography-of-uterine-blood-flow-in-ewes-during-pregnancy
#17
Renato Travassos Beltrame, Carolina Covre, Lucas Buss Littig, Amanda de Barros Martins, Celia Raquel Quirino, Aylton Bartholazzi Junior, Ricardo Lopes Dias da Costa
In sheep, there is a lack of information on the behaviour of hemodynamic indices and parameters of blood flow velocity of the uterine artery during pregnancy, making it impossible to determine the real meaning of the values found and their probable relevance in normal physiological or pathological states. The objective of the present study was to evaluate the blood flow velocity parameters and hemodynamic indices of the uterine artery in ewes (18) during pregnancy (33). Based on non-invasive colour Doppler sonography, we evaluated the peak systolic velocity (PS), end diastolic velocity (ED), time-averaged maximum and minimum velocity in a cardiac cycle (TAMAX and TAMEAN), pulsatility index (PI), resistance index (RI), systolic/diastolic ratio (S/D), heart rate (HR), arterial diameter (AD) and the blood flow volume (BFV)...
March 15, 2017: Theriogenology
https://www.readbyqxmd.com/read/28214972/avocado-oil-induces-long-term-alleviation-of-oxidative-damage-in-kidney-mitochondria-from-type-2-diabetic-rats-by-improving-glutathione-status
#18
Omar Ortiz-Avila, María Del Consuelo Figueroa-García, Claudia Isabel García-Berumen, Elizabeth Calderón-Cortés, Jorge A Mejía-Barajas, Alain R Rodriguez-Orozco, Ricardo Mejía-Zepeda, Alfredo Saavedra-Molina, Christian Cortés-Rojo
Hyperglycemia and mitochondrial ROS overproduction have been identified as key factors involved in the development of diabetic nephropathy. This has encouraged the search for strategies decreasing glucose levels and long-term improvement of redox status of glutathione, the main antioxidant counteracting mitochondrial damage. Previously, we have shown that avocado oil improves redox status of glutathione in liver and brain mitochondria from streptozotocin-induced diabetic rats; however, the long-term effects of avocado oil and its hypoglycemic effect cannot be evaluated because this model displays low survival and insulin depletion...
February 18, 2017: Journal of Bioenergetics and Biomembranes
https://www.readbyqxmd.com/read/28214945/characterization-of-tunneling-nanotubes-in-wharton-s-jelly-mesenchymal-stem-cells-an-intercellular-exchange-of-components-between-neighboring-cells
#19
Viviana Sanchez, Nerina Villalba, Luciano Fiore, Carlos Luzzani, Santiago Miriuka, Alberto Boveris, Ricardo J Gelpi, Alicia Brusco, Juan José Poderoso
Intercellular communication is one of the most important events in cell population behavior. In the last decade, tunneling nanotubes (TNTs) have been recognized as a new form of long distance intercellular connection. TNT function is to allow molecular and subcellular structure exchange between neighboring cells via the transfer of molecules and organelles such as calcium ions, prions, viral and bacterial pathogens, small lysosomes and mitochondria. New findings support the concept that mesenchymal stem cells (MSCs) can affect cell microenvironment by the release of soluble factors or the transfer of cellular components to neighboring cells, in a way which significantly contributes to cell regulation and tissue repair, although the underlying mechanisms remain poorly understood...
February 18, 2017: Stem Cell Reviews
https://www.readbyqxmd.com/read/28214641/posterior-reversible-encephalopathy-syndrome-causing-vision-loss-following-endoscopic-endonasal-resection-of-pituitary-adenoma-a-case-report
#20
Nicolas W Villelli, Daniel M Prevedello, Daniel S Ikeda, Alaa S Montaser, Bradley A Otto, Ricardo L Carrau
BACKGROUND: Posterior Reversible Encephalopathy Syndrome (PRES) is characterized by headache, altered mental status, visual changes, and seizure combined with brain imaging consistent with cerebral edema without infarction. To the best of our knowledge, we report the first case of PRES following an endoscopic endonasal resection of a pituitary macroadenoma. CASE DESCRIPTION: A 59-year-old female was diagnosed with a pituitary macroadenoma, for which she underwent endoscopic endonasal extracapsular resection...
February 15, 2017: World Neurosurgery
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