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Elastography ARFI

Yasser A Elhosary, Saleh M Saleh, Wafaa M Ezzat, Dirk-André Clevert
BACKGROUND: Acoustic radiation force impulse (ARFI) evaluates liver stiffness non-invasively and was invented recently. This technique can easily and accurately assess the degree of liver fibrosis in clinical practice. AIM: The aim of this study was to detect the diagnostic performance of ARFI elastography in the staging of fibrosis in some Egyptian patients with chronic HCV infection. PATIENTS AND METHODS: One hundred ninety patients with chronic HCV infection; 142 men and 48 women were enrolled in the study...
September 15, 2016: Open Access Macedonian Journal of Medical Sciences
Steffen Zopf, Lara Rösch, Peter C Konturek, Ruediger S Goertz, Markus F Neurath, Deike Strobel
BACKGROUND Non-invasive procedures such as acoustic radiation force impulse imaging (ARFI) shear-wave elastography are currently used for the assessment of liver fibrosis. In the course of chronic hepatitis C, significant liver fibrosis or cirrhosis develops in approximately 25% of patients, which is a negative predictor of antiviral treatment response. Cirrhosis can be prevented by successful virus elimination. In this prospective study, a pretreatment ARFI cutoff value of 1.5 m/s was evaluated in relation to sustained virological response to anti-HCV therapy...
2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Maya Balakrishnan, Fernanda Souza, Carolina Muñoz, Salvador Augustin, Nicole Loo, Yanhong Deng, Maria Ciarleglio, Guadalupe Garcia-Tsao
OBJECTIVES: Measurements of liver stiffness and spleen stiffness are useful noninvasive ways to assess fibrosis and portal hypertension in patients with chronic liver disease. One method for assessing stiffness is by point shear wave elastography via acoustic radiation force impulse imaging (ARFI). Its advantage is that sites where stiffness is measured are visualized sonographically. However, its reliability has not been well established, and all studies done to date evaluating the use of ARFI in chronic liver disease have been performed outside the United States...
September 23, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Liang Wang
Acoustic radiation force impulse (ARFI) imaging is an emerging technique with great promise in the field of elastography. Previous studies have validated ARFI quantification as a method of estimating fibrosis in chronic liver disease. Similarly, fibrosis is the principal process underlying the progression of chronic kidney disease, which is the major cause of renal failure. However, the quantification of tissue stiffness using ARFI imaging is more complex in the kidney than in the liver. Moreover, not all previous studies are comparable because they employed different procedures...
October 2016: Ultrasonography
Katharina Hollerieth, Bernhard Gaßmann, Stefan Wagenpfeil, Philipp Moog, Minh-Truc Vo-Cong, Uwe Heemann, Konrad Friedrich Stock
PURPOSE: The purpose of this study was to compare the reliability of ultrasound-based shear wave elastography in regions of homogeneous versus heterogeneous elasticity by using two different probes. METHODS: Using acoustic radiation force impulse (ARFI) elastography, we measured the shear wave velocity (SWV) in different lesions of an elastography phantom with the convex 4C1 probe and the linear 9L4 probe. The region of interest (ROI) was positioned in such a way that it was partly filled by one of the lesions (0%, 25%, 50%, 75%, and 100%) and partly by the background of the phantom (100%, 75%, 50%, 25%, and 0%, respectively)...
October 2016: Ultrasonography
Bao-Ding Chen, Hui-Xiong Xu, Yi-Feng Zhang, Bo-Ji Liu, Le-Hang Guo, Dan-Dan Li, Chong-Ke Zhao, Xiao-Long Li, Dan Wang, Shuang-Shuang Zhao
BACKGROUND: Non-calcified thyroid nodules are relatively difficult to diagnose only relying at conventional US images. OBJECTIVE: To investigate the diagnostic performances of conventional strain elastography (SE), acoustic radiation force impulse (ARFI) SE and point shear-wave speed (pSWS) for non-calcified thyroid nodules. METHODS: A total of 201 non-calcified thyroid nodules in 195 patients were studied. They were examined with conventional ultrasound (US), conventional SE, ARFI SE and pSWS...
August 16, 2016: Clinical Hemorheology and Microcirculation
Florian Bert, Jona T Stahmeyer, Siegbert Rossol
BACKGROUND: Early discovery of liver fibrosis is becoming more popular because of enhanced incidence of hepatocellular carcinoma. Ultrasound-based liver elastography is a method used to approve suspected liver fibrosis or cirrhosis. We assessed the clinical usefulness of acoustic radiation force impulse shear wave elasticity imaging (ARFI-SWEI) as a preventive screening method to uncover fibrosis. METHODS: We screened 382 patients by native routine sonography for abnormal liver results and divided them into six groups: group 1: normal liver, groups 2-4: fatty liver grade I-III, group 5: liver cirrhosis, and group 6: inhomogenic liver tissue...
September 2016: Journal of Clinical Medicine Research
Malene Roland Pedersen, Palle Jørn Sloth Osther, Søren Rafael Rafaelsen
BACKGROUND: Elastography of the testis can be used as a part of multiparametric examination of the scrotum. PURPOSE: To determine the testicular stiffness using acoustic radiation force impulse imaging (ARFI) technique in men with testicular microlithiasis (TML). MATERIAL AND METHODS: In 2013, 12 patients with diagnosed testicular microlithiasis in 2008 (mean age, 51 years; age range, 25-76 years) underwent a 5-year follow-up B-mode ultrasonography with three ARFI elastography measurements of each testis...
July 2016: Acta Radiologica Open
V Knop, D Hoppe, T Welzel, J Vermehren, E Herrmann, A Vermehren, M Friedrich-Rust, C Sarrazin, S Zeuzem, M-W Welker
It is still controversial, whether and to what amount cirrhosis and portal hypertension are reversible in patients with hepatitis C virus (HCV)-associated cirrhosis and sustained virologic response (SVR) after interferon-free antiviral therapy. In this study, we prospectively evaluated dynamics of liver and spleen stiffness in HCV-infected patients with advanced liver disease and SVR after interferon-free treatment. A total of 54 patients with HCV-associated cirrhosis and SVR were included. Liver and spleen stiffness was measured at therapy baseline (BL), end of treatment (EOT) and 24 weeks after EOT (FU24) by transient liver elastography (L-TE) as well as by acoustic radiation force impulse of the liver (L-ARFI) and spleen (S-ARFI), as well as biochemical, virologic and clinical data...
August 8, 2016: Journal of Viral Hepatitis
Laura Kassym, Mohammed A Nounou, Zauresh Zhumadilova, Asad I Dajani, Nurgul Barkibayeva, Ayan Myssayev, Tolebay Rakhypbekov, Adnan M Abuhammour
BACKGROUND: The diagnosis of chronic liver disease (CLD) leading to fibrosis, cirrhosis, and portal hypertension had witnessed dramatic changes after the introduction of noninvasive figure accessible tools over the past few years. Imaging techniques that are based on evaluation of the liver stiffness was particularly useful in this respect. Acoustic radiation force impulse (ARFI) emerged as an interesting figure tool with reliable repute and high precision. AIMS: To evaluate liver stiffness measurement (LSM) and splenic stiffness measurement (SSM) in healthy volunteers as concluded by the ARFI technique and to out a numeric calculated ratio that may reflect their correlation in the otherwise healthy liver...
July 2016: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
JianQiao Zhou, ZhiFang Yang, WeiWei Zhan, YiJie Dong, Chun Zhou
The goal of our study was to investigate the anisotropy of normal breast glandular and fatty tissue with acoustic radiation force impulse (ARFI) quantification. A total of 137 breasts in 137 women were enrolled. These breasts were divided into the duct-apparent group and the duct-inapparent group, divided into the ligament-apparent group and the ligament-inapparent group. Shear wave velocity (SWV) in the radial (SWV(r)) and anti-radial (SWV(a-r)) directions was measured. The elastic anisotropy of glandular tissue and fatty tissue was evaluated as the ratio between SWV(r) and SWV(a-r)...
October 2016: Ultrasound in Medicine & Biology
Erbil Karaman, Harun Arslan, Orkun Çetin, Hanιm Güler Şahin, Aydin Bora, Alparslan Yavuz, Sadi Elasan, İbrahim Akbudak
AIM: The aim of this research was to study and compare placental elasticity with acoustic radiation force impulse (ARFI) elastography in pre-eclamptic and normal pregnancies. METHODS: A total of 107 singleton pregnancies in the third trimester (38 healthy control subjects, 34 patients with gestational hypertension, and 35 pre-eclampsia patients) were included in the study. ARFI elastography was used to determine the placental elasticity in the three predetermined regions of the placenta (the fetal edge, maternal edge, and central part of the placenta)...
July 26, 2016: Journal of Obstetrics and Gynaecology Research
Camilo Julio Llamoza-Torres, Maria Fuentes-Pardo, Francisco Javier Álvarez-Higueras, Fernando Alberca-de-Las-Parras, Fernando Carballo-Álvarez
OBJECTIVE: To determine the accuracy of the acoustic radiation force impulse (ARFI) technique for the diagnosis of chronic pancreatitis. MATERIALS AND METHODS: We present an observational, single-center study that included patients with suspected chronic pancreatitis in the period between October 2012 and September 2015 who underwent endoscopic ultrasound (EUS) and were classified according to the standard and Rosemont criteria. The same group of patients was assessed by the ARFI technology using ACUSON S2000™ equipment with Virtual Touch™ Quantification software for the assessment of pancreatic stiffness by obtaining the shear wave velocity (SWV) in the head, body and tail of the pancreas...
August 2016: Revista Española de Enfermedades Digestivas
Bircan Alan, Senem Tunç, Elif Agacayak, Aslan Bilici
OBJECTIVE: To assess the value of placental shear wave velocity (SWV) measurement by acoustic radiation force impulse (ARFI) imaging for the diagnosis of pre-eclampsia and to determine the relationship between the SWV and the severity of pre-eclampsia. METHODS: A prospective study was performed at a center in Turkey between August 2014 and March 2015. The study included consecutive pregnant women in the second or third trimester diagnosed with pre-eclampsia and healthy pregnant women without pre-eclampsia of similar ages...
October 2016: International Journal of Gynaecology and Obstetrics
Yi-Hung Lin, Ming-Lun Yeh, Ching-I Huang, Jeng-Fu Yang, Po-Cheng Liang, Chung-Feng Huang, Chia-Yen Dai, Zu-Yau Lin, Shinn-Cherng Chen, Jee-Fu Huang, Ming-Lung Yu, Wan-Long Chuang
Sonography-based noninvasive liver fibrosis assessment is promising in the prediction of treatment efficacy and prognosis in chronic liver disease (CLD) patients. Acoustic radiation force impulse imaging (ARFI) is a newly-developed transient elastography (TE) method integrated into a conventional ultrasound machine. The study aimed to assess the performance of ARFI imaging in the diagnosis of liver fibrosis in Taiwanese CLD patients. We also aimed to search for the optimal cut-off values in different fibrosis stages...
July 2016: Kaohsiung Journal of Medical Sciences
Christine Neuwirt, Heike Jaeger, Wolfgang Kratzer, Suemeyra Tasdemir, Mark Martin Haenle, Tilmann Graeter
OBJECTIVES: To investigate potential subject-related confounding factors for thyroid acoustic radiation force impulse (ARFI) elastography. METHODS AND MATERIALS: A total of 194 subjects participated in the study. RESULTS: The standard values in the right lobe were 2.52±0.35m/s (ventral half) and 2.43±0.40m/s (dorsal half). In the left lobe, velocities of 2.56±0.37m/s (ventral) and 2.48±0.42m/s (dorsal) were noted. A clear difference was observed between measurement values in the ventral and dorsal half (P<...
September 2016: Clinical Imaging
Christian Fischer, Daniel Krammer, Andreas Hug, Marc-André Weber, Hans-Ulrich Kauczor, Martin Krix, Thomas Bruckner, Pierre Kunz, Gerhard Schmidmaier, Felix Zeifang
BACKGROUND: The outcome after reverse shoulder arthroplasty (RSA) depends on the condition of the deltoid muscle, which we assessed with new ultrasound modalities and electromyography (EMG). Contrast-enhanced ultrasound (CEUS) and acoustic radiation force impulse (ARFI) were applied to assess perfusion and elasticity of the deltoid muscle compared with the clinical and functional outcome. METHODS: The study recruited 64 patients (mean age, 72.9 years) treated with RSA between 2004 and 2013...
June 30, 2016: Journal of Shoulder and Elbow Surgery
D Attia, H Bantel, H Lenzen, M P Manns, M J Gebel, A Potthoff
BACKGROUND: Obesity and overweight are global health problems. AIM: To evaluate the diagnostic accuracy of liver stiffness measurement (LSM) using acoustic radiation force impulse (ARFI) elastography in overweight and obese patients for staging liver fibrosis. METHODS: Ninety-seven patients (mean age: 50 years, 50% male) with body mass index (BMI) ≥25 kg/m(2) (mean BMI: 31 kg/m(2) ) were prospectively enrolled. All patients underwent ARFI elastography and liver biopsy...
August 2016: Alimentary Pharmacology & Therapeutics
Y Tachi, T Hirai, Y Kojima, A Miyata, K Ohara, Y Ishizu, T Honda, T Kuzuya, K Hayashi, M Ishigami, H Goto
BACKGROUND: Acoustic radiation force impulse (ARFI) elastography is a non-invasive method for measuring liver stiffness. However, there are no reports evaluating the value of ARFI elastography for liver fibrosis in chronic hepatitis C patients with a sustained virological response (SVR). AIM: To investigate the diagnostic performance of ARFI elastography for the assessment of liver fibrosis in hepatitis C virus (HCV) infected patients with an SVR. METHODS: In this prospective study, we enrolled 336 patients: 121 HCV patients with an SVR (44...
August 2016: Alimentary Pharmacology & Therapeutics
Chris L de Korte, Stein Fekkes, Aart J Nederveen, Rashindra Manniesing, Hendrik Rik H G Hansen
Cardiovascular disease (CVD) is a leading cause of death and is in the majority of cases due to the formation of atherosclerotic plaques in arteries. Initially, thickening of the inner layer of the arterial wall occurs. Continuation of this process leads to plaque formation. The risk of a plaque to rupture and thus to induce an ischemic event is directly related to its composition. Consequently, characterization of the plaque composition and its proneness to rupture are of crucial importance for risk assessment and treatment strategies...
October 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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