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https://www.readbyqxmd.com/read/28933748/dietary-composition-independent-of-weight-loss-in-the-management-of-non-alcoholic-fatty-liver-disease
#1
REVIEW
Tannaz Eslamparast, Puneeta Tandon, Maitreyi Raman
Poor dietary composition is an important factor in the progression of non-alcoholic fatty liver disease (NAFLD). The majority of NAFLD patients follow diets with overconsumption of simple carbohydrates, total and saturated fat, with reduced intake of dietary fiber and omega-3 rich foods. Although lifestyle modifications including weight loss and exercise remain the keystone of NAFLD management, modifying dietary composition with or without a calorie-restricted diet may also be a feasible and sustainable strategy for NAFLD treatment...
July 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28932990/treatment-opportunities-in-patients-with-metabolic-myopathies
#2
REVIEW
Mette Cathrine Ørngreen, John Vissing
Metabolic myopathies are disorders affecting utilization of carbohydrates or fat in the skeletal muscle. Adult patients with metabolic myopathies typically present with exercise-induced pain, contractures or stiffness, fatigue, and myoglobinuria. Symptoms are related to energy failure. Purpose of review In this review, the current treatment options, including exercise therapy, dietary treatment, pharmacological supplementation, gene transcription, and enzyme replacement therapy, are described. Recent findings Recognition of the metabolic block in the metabolic myopathies has started the development of new therapeutic options...
September 21, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28929343/a-comparison-of-isomaltulose-versus-maltodextrin-ingestion-during-soccer-specific-exercise
#3
Emma J Stevenson, Anthony Watson, Stephan Theis, Anja Holz, Liam D Harper, Mark Russell
PURPOSE: The performance and physiological effects of isomaltulose and maltodextrin consumed intermittently during prolonged soccer-specific exercise were investigated. METHODS: University soccer players (n = 22) performed 120 min of intermittent exercise while consuming 8% carbohydrate-electrolyte drinks (equivalent to ~ 20 g h(-1)) containing maltodextrin (Glycaemic Index: 90-100), isomaltulose (Glycaemic Index: 32) or a carbohydrate-energy-free placebo in a manner replicating the practices of soccer players (i...
September 19, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28919844/practical-nutritional-recovery-strategies-for-elite-soccer-players-when-limited-time-separates-repeated-matches
#4
REVIEW
Mayur Krachna Ranchordas, Joel T Dawson, Mark Russell
Specific guidelines that aim to facilitate the recovery of soccer players from the demands of training and a congested fixture schedule are lacking; especially in relation to evidence-based nutritional recommendations. The importance of repeated high level performance and injury avoidance while addressing the challenges of fixture scheduling, travel to away venues, and training commitments requires a strategic and practically feasible method of implementing specific nutritional strategies. Here we present evidence-based guidelines regarding nutritional recovery strategies within the context of soccer...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28919842/international-society-of-sports-nutrition-position-stand-nutrient-timing
#5
REVIEW
Chad M Kerksick, Shawn Arent, Brad J Schoenfeld, Jeffrey R Stout, Bill Campbell, Colin D Wilborn, Lem Taylor, Doug Kalman, Abbie E Smith-Ryan, Richard B Kreider, Darryn Willoughby, Paul J Arciero, Trisha A VanDusseldorp, Michael J Ormsbee, Robert Wildman, Mike Greenwood, Tim N Ziegenfuss, Alan A Aragon, Jose Antonio
The International Society of Sports Nutrition (ISSN) provides an objective and critical review regarding the timing of macronutrients in reference to healthy, exercising adults and in particular highly trained individuals on exercise performance and body composition. The following points summarize the position of the ISSN:Nutrient timing incorporates the use of methodical planning and eating of whole foods, fortified foods and dietary supplements. The timing of energy intake and the ratio of certain ingested macronutrients may enhance recovery and tissue repair, augment muscle protein synthesis (MPS), and improve mood states following high-volume or intense exercise...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28902115/repeated-high-intensity-cycling-performance-is-unaffected-by-timing-of-carbohydrate-ingestion
#6
Ren-Jay Shei, Hunter L Paris, Christopher P Beck, Robert F Chapman, Timothy D Mickleborough
To determine whether carbohydrate feeding taken immediately before, early, or late in a series of high-intensity cycling exercises affected cycling performance 16 trained, male cyclists (> 6hr post-prandial) performed three, 4-km cycling time trials (TT1, TT2, TT3) separated by 15 min of active recovery on four separate occasions. Carbohydrate feeding (80g) was given either before TT1 (PRE1), before TT2 (PRE2), before TT3 (PRE3), or not at all (control, CTL). Treatment order was randomized. Sweet-placebo was given prior to the other time trials...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28894645/re-examination-of-the-contribution-of-substrates-to-energy-expenditure-during-high-intensity-intermittent-exercise-in-endurance-athletes
#7
Zübeyde Aslankeser, Şükrü Serdar Balcı
BACKGROUND: It has been believed that the contribution of fat oxidation to total energy expenditure is becoming negligible at higher exercise intensities (about 85% VO2max). The aim of the present study was to examine the changes in substrate oxidation during high-intensity interval exercise in young adult men. METHODS: A total of 18 healthy well-trained (aged 19.60 ± 0.54 years, BMI = 22.19 ± 0.64 kg/m(2), n = 10) and untrained (aged 20.25 ± 0.41 years, BMI = 22...
2017: PeerJ
https://www.readbyqxmd.com/read/28882528/impaired-glycogen-breakdown-and-synthesis-in-phosphoglucomutase-1-deficiency
#8
Nicolai Preisler, Jonathan Cohen, Christoffer Rasmus Vissing, Karen Lindhardt Madsen, Katja Heinicke, Lydia Jane Sharp, Lauren Phillips, Nadine Romain, Sun Young Park, Marta Newby, Phil Wyrick, Pedro Mancias, Henrik Galbo, John Vissing, Ronald Gerald Haller
OBJECTIVE: We investigated metabolism and physiological responses to exercise in an 18-year-old woman with multiple congenital abnormalities and exertional muscle fatigue, tightness, and rhabdomyolysis. METHODS: We studied biochemistry in muscle and fibroblasts, performed mutation analysis, assessed physiological responses to forearm and cycle-ergometer exercise combined with stable-isotope techniques and indirect calorimetry, and evaluated the effect of IV glucose infusion and oral sucrose ingestion on the exercise response...
August 25, 2017: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/28871893/metabolism-and-whole-body-fat-oxidation-following-post-exercise-carbohydrate-or-protein-intake
#9
Ulrika Andersson Hall, Stefan Pettersson, Fredrik Edin, Anders Pedersen, Daniel Malmodin, Klavs Madsen
PURPOSE: This study investigated how post-exercise intake of placebo (PLA), protein (PRO) or carbohydrate (CHO) affected fat oxidation (FO) and metabolic parameters during recovery and subsequent exercise. METHODS: In a cross-over design, 12 moderately trained women (VO2max 45 ± 6 ml·min(-1)·kg(-1)) performed three days of testing. A 23 min control (CON) incremental FO bike test (30-80% VO2max) was followed by 60 min exercise at 75% VO2max. Immediately post-exercise, subjects ingested PLA, 20 g PRO or 40 g CHO followed by a second FO bike test 2h later...
September 5, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28871832/adding-fish-oil-to-whey-protein-leucine-and-carbohydrate-over-a-6-week-supplementation-period-attenuates-muscle-soreness-following-eccentric-exercise-in-competitive-soccer-players
#10
Jordan D Philpott, Chris Donnelly, Ian H Walshe, James Dick, Stuart D R Galloway, Kevin D Tipton, Oliver C Witard
Soccer players often experience eccentric exercise-induced muscle damage given the physical demands of soccer match-play. Since long chain n-3 polyunsaturated fatty acids (n-3PUFA) enhance muscle sensitivity to protein supplementation, dietary supplementation with a combination of fish oil-derived n-3PUFA, protein and carbohydrate may promote exercise recovery. This study examined the influence of adding n-3PUFA to a whey protein, leucine and carbohydrate containing beverage over a 6 week supplementation period on physiological markers of recovery measured over 3 days following eccentric exercise...
September 5, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28862046/glucose-metabolism-and-metabolic-flexibility-in-cultured-skeletal-muscle-cells-is-related-to-exercise-status-in-young-male-subjects
#11
Jenny Lund, Daniel S Tangen, Håvard Wiig, Hans K Stadheim, Siw A Helle, Jesper B Birk, Thorsten Ingemann-Hansen, Arild C Rustan, G Hege Thoresen, Jørgen F P Wojtaszewski, Eili T Kase, Jørgen Jensen
We hypothesised that skeletal muscles of healthy young people have a large variation in oxidative capacity and fibre-type composition, and aimed therefore to investigate glucose metabolism in biopsies and myotubes isolated from musculus vastus lateralis from healthy males with varying degrees of maximal oxygen uptake. Trained and intermediary trained subjects showed higher carbohydrate oxidation in vivo. Fibre-type distribution in biopsies and myotubes did not differ between groups. There was no correlation between fibre-type I expression in biopsies and myotubes...
September 1, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28859408/fuel-use-in-mammals-conserved-patterns-and-evolved-strategies-for-aerobic-locomotion-and-thermogenesis
#12
Grant B McClelland, Sulayman A Lyons, Cayleih E Robertson
Effective aerobic locomotion depends on adequate delivery of oxygen and an appropriate allocation of metabolic substrates. The use of metabolic substrates during exercise follows a predictive pattern of lipid and carbohydrate oxidation that is similar in lowland native cursorial mammals. We have found that in two highland lineages of mice (Phyllotis and Peromyscus) the fuel use pattern is shifted to a greater reliance on carbohydrates compared to their lowland conspecifics and congenerics. However, there is variation between lineages in the importance of phenotypic plasticity in the expression of this metabolic phenotype...
August 1, 2017: Integrative and Comparative Biology
https://www.readbyqxmd.com/read/28855275/dynamic-proteome-profiling-of-individual-proteins-in-human-skeletal-muscle-after-a-high-fat-diet-and-resistance-exercise
#13
Donny M Camera, Jatin G Burniston, Mark A Pogson, William J Smiles, John A Hawley
It is generally accepted that muscle adaptation to resistance exercise (REX) training is underpinned by contraction-induced, increased rates of protein synthesis and dietary protein availability. By using dynamic proteome profiling (DPP), we investigated the contribution of both synthesis and breakdown to changes in abundance on a protein-by-protein basis in human skeletal muscle. Age-matched, overweight males consumed 9 d of a high-fat, low-carbohydrate diet during which time they either undertook 3 sessions of REX or performed no exercise...
August 30, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28855239/closed-loop-control-during-intense-prolonged-outdoor-exercise-in-adolescents-with-type-1-diabetes-the-artificial-pancreas-ski-study
#14
Marc D Breton, Daniel R Cherñavvsky, Gregory P Forlenza, Mark D DeBoer, Jessica Robic, R Paul Wadwa, Laurel H Messer, Boris P Kovatchev, David M Maahs
OBJECTIVE: Intense exercise is a major challenge to the management of type 1 diabetes (T1D). Closed loop control (CLC) systems (artificial pancreas) improve glycemic control during limited intensity and short duration of physical activity (PA). However, CLC has not been tested during extended vigorous outdoor exercise common among adolescents. RESEARCH DESIGN AND METHODS: Skiing presents unique metabolic challenges: intense prolonged PA, cold, altitude, and stress/fear/excitement...
August 30, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28836234/weight-management-in-patients-with-type-1-diabetes-and-obesity
#15
REVIEW
Adham Mottalib, Megan Kasetty, Jessica Y Mar, Taha Elseaidy, Sahar Ashrafzadeh, Osama Hamdy
PURPOSE OF REVIEW: Patients with type 1 diabetes (T1D) are typically viewed as lean individuals. However, recent reports showed that their obesity rate surpassed that of the general population. Patients with T1D who show clinical signs of type 2 diabetes such as obesity and insulin resistance are considered to have "double diabetes." This review explains the mechanisms of weight gain in patients with T1D and how to manage it. RECENT FINDINGS: Weight management in T1D can be successfully achieved in real-world clinical practice...
August 23, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28828762/effects-of-different-doses-of-silk-peptide-on-energy-metabolism-during-exercise-in-mice
#16
Jisu Kim, Jonghoon Park, Bokyung Kim, Chi-Ho Lee, Kiwon Lim, Heajung Suh
PURPOSE: This study was carried out to determine the optimal dose of silk peptide for enhancing fat metabolism during exercise. METHODS: Fifty male ICR mice were randomly divided into five groups: Sed, SP0, SP200, SP400, and SP800. All SP mice underwent training by running on a treadmill 5 times a week for 2 weeks (20 m/min, 8° slope, 50 min/day for the first week and 25 m/min, 8° slope, 50 min/day at about 70-75% of maximum oxygen uptake for the second week)...
March 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28826372/%C3%AE-hydroxybutyrate-a-signaling-metabolite
#17
John C Newman, Eric Verdin
Various mechanisms in the mammalian body provide resilience against food deprivation and dietary stress. The ketone body β-hydroxybutyrate (BHB) is synthesized in the liver from fatty acids and represents an essential carrier of energy from the liver to peripheral tissues when the supply of glucose is too low for the body's energetic needs, such as during periods of prolonged exercise, starvation, or absence of dietary carbohydrates. In addition to its activity as an energetic metabolite, BHB is increasingly understood to have cellular signaling functions...
August 21, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28825605/effect-of-carbohydrate-caffeine-and-carbohydrate-caffeine-mouth-rinsing-on-intermittent-running-performance-in-collegiate-male-lacrosse-athletes
#18
Patrick Dolan, Kyle E Witherbee, Kimi M Peterson, Chad M Kerksick
Dolan, P, Witherbee, KE, Peterson, KM, and Kerksick, CM. Effect of carbohydrate, caffeine, and carbohydrate + caffeine mouth rinsing on intermittent running performance in collegiate male lacrosse athletes. J Strength Cond Res 31(9): 2473-2479, 2017-Recently, an interest has developed in the potential to rinse the oral cavity with key nutrients to impact various types of exercise and presumably sporting performance. Although multiple studies examining carbohydrate mouth rinsing have been completed, conflicting evidence surrounding caffeine mouth rinsing persists, and no research has explored its ability to impact high-intensity, intermittent running performance...
September 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28806275/effects-of-creatine-and-carbohydrate-loading-on-cycling-time-trial-performance
#19
Kristyen A Tomcik, Donny M Camera, Julia L Bone, Megan L Ross, Nikki A Jeacocke, Bill Tachtsis, Joan Senden, Luc J C van Loon, John A Hawley, Louise M Burke
INTRODUCTION: Creatine- and carbohydrate-loading are dietary strategies used to enhance exercise capacity. This study examined the metabolic and performance effects of a combined creatine and CHO-loading regiment on time-trial (TT) cycling bouts. METHODS: Eighteen well-trained (~65mL[BULLET OPERATOR]kg[BULLET OPERATOR]min VO2peak) males completed three performance trials (PT) comprised of a 120-km cycling TT interspersed with alternating 1- and 4-km sprints (6 sprints each) performed every 10-km followed by an inclined ride to fatigue (~90% VO2peak)...
August 11, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28806049/electrolytes-oral-electrolyte-solutions
#20
Lisa Harris
Oral electrolyte solutions are used widely for rehydration in diarrheal illness and to maintain hydration during vigorous exercise. In diarrheal illness, an oral rehydration solution (ORS) typically is preferred over intravenous fluids except for patients with severe dehydration. The preferred ORS is one similar to the glucose-containing reduced osmolarity World Health Organization ORS. There also are polymer-based solutions that use rice or wheat as the source of carbohydrates but these are not widely recommended...
August 2017: FP Essentials
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