keyword
https://read.qxmd.com/read/38531748/development-of-a-machine-learning-model-for-prediction-of-the-duration-of-unassisted-spontaneous-breathing-in-patients-during-prolonged-weaning-from-mechanical-ventilation
#1
JOURNAL ARTICLE
Sebastian Johannes Fritsch, Morris Riedel, Gernot Marx, Johannes Bickenbach, Andreas Schuppert
PURPOSE: Treatment of patients undergoing prolonged weaning from mechanical ventilation includes repeated spontaneous breathing trials (SBTs) without respiratory support, whose duration must be balanced critically to prevent over- and underload of respiratory musculature. This study aimed to develop a machine learning model to predict the duration of unassisted spontaneous breathing. MATERIALS AND METHODS: Structured clinical data of patients from a specialized weaning unit were used to develop (1) a classifier model to qualitatively predict an increase of duration, (2) a regressor model to quantitatively predict the precise duration of SBTs on the next day, and (3) the duration difference between the current and following day...
March 26, 2024: Journal of Critical Care
https://read.qxmd.com/read/38528264/two-lung-ventilation-with-artificial-pneumothorax-on-cerebral-desaturation-and-early-postoperative-cognitive-outcome-a-randomized-controlled-trial
#2
JOURNAL ARTICLE
Lihua Lei, Yanlin Wu, Wencong Chen, Min Chen, Qiaoping Liu, Wenshu Chen, Qun Lin
BACKGROUND: The effect of two lung ventilation (TLV) with carbon dioxide artificial pneumothorax on cerebral desaturation and postoperative neurocognitive changes in elderly patients undergoing elective minimally invasive esophagectomy (MIE) is unclear. OBJECTIVES: The first aim of this study was to compare the effect of TLV and one lung ventilation (OLV) on cerebral desaturation. The second aim was to assess changes in early postoperative cognitive outcomes of two ventilation methods...
March 25, 2024: Surgical Endoscopy
https://read.qxmd.com/read/38528066/a-predictive-model-for-post-thoracoscopic-surgery-pulmonary-complications-based-on-the-pbnn-algorithm
#3
JOURNAL ARTICLE
Cheng-Mao Zhou, Qiong Xue, HuiJuan Li, Jian-Jun Yang, Yu Zhu
We constructed an early prediction model for postoperative pulmonary complications after thoracoscopic surgery using machine learning and deep learning algorithms. The artificial intelligence prediction models were built in Python, primarily using artificial intelligencealgorithms including both machine learning and deep learning algorithms. Correlation analysis showed that postoperative pulmonary complications were positively correlated with age and surgery duration, and negatively correlated with serum albumin...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38518051/the-intervention-of-artificial-intelligence-to-improve-the-weaning-outcomes-of-patients-with-mechanical-ventilation-practical-applications-in-the-medical-intensive-care-unit-and-the-covid-19-intensive-care-unit-a-retrospective-study
#4
JOURNAL ARTICLE
Yang-Han Lin, Ting-Chia Chang, Chung-Feng Liu, Chih-Cheng Lai, Chin-Ming Chen, Willy Chou
Patients admitted to intensive care units (ICU) and receiving mechanical ventilation (MV) may experience ventilator-associated adverse events and have prolonged ICU length of stay (LOS). We conducted a survey on adult patients in the medical ICU requiring MV. Utilizing big data and artificial intelligence (AI)/machine learning, we developed a predictive model to determine the optimal timing for weaning success, defined as no reintubation within 48 hours. An interdisciplinary team integrated AI into our MV weaning protocol...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38511126/nebulized-furosemide-for-pulmonary-inflammation-in-intubated-patients-with-covid-19-a-phase-2-randomized-controlled-double-blind-study
#5
JOURNAL ARTICLE
John Muscedere, David M Maslove, Christopher J Barden, Donald F Weaver, J Gordon Boyd, Stephanie Sibley, Tracy Boyd, Oleksa Rewa, Martin Albert, Marios Roussos, Patrick A Norman, Andrew G Day
OBJECTIVES: Respiratory failure secondary to COVID-19 is associated with morbidity and mortality. Current anti-inflammatory therapies are effective but are given systemically and have significant side effects. Furosemide has anti-inflammatory properties, can be administered by inhalation, and is inexpensive. We investigated the efficacy of nebulized furosemide as an adjunctive therapy for COVID-19 respiratory failure. DESIGN: A double-blind, randomized, placebo-controlled trial...
February 2024: Critical care explorations
https://read.qxmd.com/read/38506888/association-between-a-low-risk-covid-19-extracorporeal-membrane-oxygenation-criteria-and-mortality-a-retrospective-study
#6
JOURNAL ARTICLE
Igor Gostyuzhev, Adham Mohamed, Carole E Freiberger-O'Keefe, Michelle M Haines, Jonathan B Kozinn
OBJECTIVE: Our study aimed to compare the outcomes of COVID-19 patients who met a low-risk inclusion criteria for veno-venous extra corporeal membrane oxygenation (VV ECMO) with those who did not meet criteria due to higher risk but were subsequently cannulated. METHODS: This was a retrospective observational cohort study that included adult patients who were placed on VV ECMO for COVID-19 related acute respiratory distress syndrome (ARDS) at a tertiary care academic medical center...
March 20, 2024: International Journal of Artificial Organs
https://read.qxmd.com/read/38505007/analysis-of-the-hemostatic-effect-of-preset-wrapping-technique-for-type-a-aortic-dissection-with-abnormal-coagulation
#7
JOURNAL ARTICLE
Zhixiang Cai, Tao Yan, Ben Zhang, Weida Zhang, Chenjie Su, Hanwei Chen, Xianyue Wang
BACKGROUND: There are many techniques to reduce anastomotic bleeding for the total arch replacement, but hemostasis is sometimes difficult to achieve after surgery for acute dissection, especially in patients with abnormal coagulation (AC). This study aimed to investigate the hemostatic effect and early efficacy of a pre-set bovine pericardium wrapper in the right heart system shunt for total arch replacement in patients with type A aortic dissection (TAAD) and preoperative AC. METHODS: A retrospective analysis was conducted on 85 patients with TAAD and AC who underwent total arch replacement between January 2018 and December 2022...
February 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38498214/predictive-role-of-regional-thigh-tissue-oxygen-saturation-monitoring-during-cardiopulmonary-bypass-in-lung-injury-after-cardiac-surgery
#8
JOURNAL ARTICLE
Tomoki Tamura, Fumiaki Shikata, Tadashi Kitamura, Masaomi Fukuzumi, Yuki Tanaka, Tomoyo Ebine, Kiyotaka Fujii, Satoshi Kohira, Kagami Miyaji
Acute respiratory distress syndrome (ARDS) is a serious complication following cardiac surgery mainly associated with the use of cardiopulmonary bypass (CPB), which could increase the risk of mortality and morbidity. This study investigated the association of regional oxygen saturation (rSO2 ) during CPB with postoperative outcomes, including respiratory function. Patients who underwent cardiac surgery with CPB from 2015 to 2019 were included. Near-infrared spectroscopy was used to monitor rSO2 at the forehead, abdomen, and thighs throughout the surgery...
March 18, 2024: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://read.qxmd.com/read/38497128/stimulatory-effect-of-methylglyoxal-on-capsaicin-sensitive-lung-vagal-afferents-in-rats-role-of-trpa1
#9
JOURNAL ARTICLE
You Shuei Lin, Nai-Ju Chan, Pei-Yu Xiao, Ching Jung Lai
Methylglyoxal (MG), a reactive metabolic byproduct of glycolysis, is a causative of painful diabetic neuropathy. Patients with diabetes are associated with more frequent severe asthma exacerbation. Stimulation of capsaicin-sensitive lung vagal (CSLV) afferents may contribute to the pathogenesis of hyperreactive airway diseases such as asthma. However, the possibility of the stimulatory effect of MG on CSLV afferents and the underlying mechanisms remain unknown. Our results showed that intravenous injection of MG (25 mg/kg, MG25) in anesthetized, spontaneously breathing rats elicited pulmonary chemoreflexes characterized by apnea, bradycardia, and hypotension...
March 18, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/38486268/flow-starvation-during-square-flow-assisted-ventilation-detected-by-supervised-deep-learning-techniques
#10
MULTICENTER STUDY
Candelaria de Haro, Verónica Santos-Pulpón, Irene Telías, Alba Xifra-Porxas, Carles Subirà, Montserrat Batlle, Rafael Fernández, Gastón Murias, Guillermo M Albaiceta, Sol Fernández-Gonzalo, Marta Godoy-González, Gemma Gomà, Sara Nogales, Oriol Roca, Tai Pham, Josefina López-Aguilar, Rudys Magrans, Laurent Brochard, Lluís Blanch, Leonardo Sarlabous
BACKGROUND: Flow starvation is a type of patient-ventilator asynchrony that occurs when gas delivery does not fully meet the patients' ventilatory demand due to an insufficient airflow and/or a high inspiratory effort, and it is usually identified by visual inspection of airway pressure waveform. Clinical diagnosis is cumbersome and prone to underdiagnosis, being an opportunity for artificial intelligence. Our objective is to develop a supervised artificial intelligence algorithm for identifying airway pressure deformation during square-flow assisted ventilation and patient-triggered breaths...
March 14, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38481306/a-review-of-the-current-status-and-progress-in-difficult-airway-assessment-research
#11
REVIEW
Haoming Chen, Yuqi Zheng, Qiang Fu, Peng Li
A difficult airway is a situation in which an anesthesiologist with more than 5 years of experience encounters difficulty with intubation or mask ventilation. According to the 2022 American Society of Anesthesiologists Practice Guidelines for the Management of Difficult Airway, difficult airways are subdivided into seven detailed categories. This condition can lead to serious adverse events and therefore must be diagnosed accurately and quickly. In this review, we comprehensively summarize and discuss the different methods used in clinical practice and research to assess difficult airways, including medical history, simple bedside assessment, comprehensive assessment of indicators, preoperative endoscopic airway examination, imaging, computer-assisted airway reconstruction, and 3D-printing techniques...
March 13, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38459726/phosgene-toxicity-clinical-manifestations-and-treatment-a-systematic-review
#12
JOURNAL ARTICLE
Alireza Asgari, Mohammadreza Parak, Yazdan Hasani Nourian, Mostafa Ghanei
Exposure to phosgene, a colourless poisonous gas, can lead to various health issues including eye irritation, a dry and burning throat, vomiting, coughing, the production of foamy sputum, difficulty in breathing, and chest pain. This systematic review aims to provide a comprehensive overview of the clinical manifestations and treatment of phosgene toxicity by systematically analyzing available literature. The search was carried out on various scientific online databases to include related studies based on inclusion and exclusion criteria with the use of PRISMA guidelines...
February 1, 2024: Cell Journal
https://read.qxmd.com/read/38456068/cardiac-rehabilitation-after-cardiac-surgery-an-important-underutilized-treatment-strategy
#13
EDITORIAL
Christos Kourek, Stavros Dimopoulos
Physical inactivity remains in high levels after cardiac surgery, reaching up to 50%. Patients present a significant loss of functional capacity, with prominent muscle weakness after cardiac surgery due to anesthesia, surgical incision, duration of cardiopulmonary bypass, and mechanical ventilation that affects their quality of life. These complications, along with pulmonary complications after surgery, lead to extended intensive care unit (ICU) and hospital length of stay and significant mortality rates. Despite the well-known beneficial effects of cardiac rehabilitation, this treatment strategy still remains broadly underutilized in patients after cardiac surgery...
February 26, 2024: World Journal of Cardiology
https://read.qxmd.com/read/38452638/anesthetic-management-of-thyroid-carcinoma-invading-the-upper-tracheal-segment-a-case-report
#14
Yuyan Ding, Lianbing Gu, Lijun Wang, Lingxi Xing, Yihu Zhou, Yueyi Jiang
INTRODUCTION AND IMPORTANCE: Intratracheal tumors account for approximately 0.2 % of respiratory tumors, including primary and secondary tumors. Secondary tumors of the upper trachea are most commonly derived from advanced thyroid cancer. Surgical resection is currently the general curative modality for thyroid cancer with tracheal invasion. Patients with tracheal tumors invading and protruding into the lumen may have reduced oxygen reserve capacity, leading to a shorter safe window for general anesthesia induction...
February 27, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38446842/percutaneous-venopulmonary-extracorporeal-membrane-oxygenation-as-bridge-to-lung-transplantation
#15
JOURNAL ARTICLE
Asad Ali Usman, Audrey Elizabeth Spelde, Wasim Lutfi, Jacob T Gutsche, William J Vernick, Omar Toubat, Salim E Olia, Edward Cantu, Andrew Courtright, Maria M Crespo, Joshua Diamond, Mauer Biscotti, Christian A Bermudez
Mechanical circulatory support (MCS) as a bridge to lung transplant is an infrequent but accepted pathway in patients who have refractory end-stage pulmonary failure. The American Association of Thoracic Surgeons Expert Consensus Guidelines, published in 2023, recommends venovenous (VV) extracorporeal membrane oxygenation (ECMO) as the initial configuration for those patients who have failed conventional medical therapy, including mechanical ventilation, while waiting for lung transplantation and needing MCS...
March 6, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38435993/the-application-of-two-drainage-angles-in-neurocritical-care-patients-with-complicated-pneumonia-a-randomized-controlled-trial
#16
Anna Zhao, Huangrong Zeng, Hui Yin, Jinlin Wang, Wenming Yuan, Chao Li, Yan Zhong, Lanlan Ma, Chongmao Liao, Hong Zeng, Yan Li
BACKGROUND: Although head elevation is an early first-line treatment for elevated intracranial pressure (ICP), the use of the head-down or prone position in managing neurocritical patients is controversial because a change in a position directly affects the intracranial and cerebral perfusion pressure, which may cause secondary brain injury and affect patient outcomes. This study compared the effects of two postural drainage positions (30° head-up tilt and 0° head flat) on the prognosis of neurocritical care patients with complicated pneumonia and a clinical pulmonary infection score (CPIS) ≥5 points to provide a reference for selecting appropriate postural drainage positions for patients with pneumonia in neurocritical care units...
2024: PeerJ
https://read.qxmd.com/read/38431593/the-impact-of-obesity-on-ventilator-associated-pneumonia-a-us-nationwide-study
#17
JOURNAL ARTICLE
Mohamad El Labban, Michella Abi Zeid Daou, Hiba Smaily, Abbas Hammoud, Ghandi Hassan, Syed Khan, Imad Bou Akl
BACKGROUND: Ventilator-associated pneumonia (VAP) is one of the leading causes of mortality in patients with critical care illness. Since obesity is highly prevalent, we wanted to study its impact on the outcomes of patients who develop VAP. METHODS: Using the National Inpatient Sample (NIS) database from 2017 to 2020, we conducted a retrospective study of adult patients with a principal diagnosis of VAP with a secondary diagnosis with or without obesity according to 10th revision of the International Statistical Classification of Diseases (ICD-10) codes...
March 2, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38426432/outcomes-of-minimally-invasive-aortic-valve-replacement-in-obese-patients-a-propensity-matched-study
#18
JOURNAL ARTICLE
Federico Cammertoni, Piergiorgio Bruno, Natalia Pavone, Marialisa Nesta, Giovanni Alfonso Chiariello, Maria Grandinetti, Serena D'Avino, Valerio Sanesi, Denise D'Errico, Massimo Massetti
INTRODUCTION: Obese patients are at risk of complications after cardiac surgery. The aim of this study is to investigate safety and efficacy of a minimally invasive approach via upper sternotomy in this setting. METHODS: We retrospectively reviewed 203 obese patients who underwent isolated, elective aortic valve replacement between January 2014 and January 2023 - 106 with minimally invasive aortic valve replacement (MIAVR) and 97 with conventional aortic valve replacement (CAVR)...
March 1, 2024: Brazilian Journal of Cardiovascular Surgery
https://read.qxmd.com/read/38423099/oxygenation-through-oral-ox66-in-a-two-hit-rodent-model-of-respiratory-distress
#19
JOURNAL ARTICLE
Bjorn K Song, Danuel A Carr, Erica D Bruce, William H Nugent
Acute respiratory distress syndrome (ARDS) is a complication of pulmonary disease that produces life-threatening hypoxaemia. Despite ventilation and hyperoxic therapies, undetected hypoxia can manifest in capillary beds leading to multi-organ failure. Ox66™ is an ingestible, solid-state form of oxygen designed to supplement oxygen deficits. Twenty-four anaesthetized rats underwent a two-hit model of respiratory distress (ARDS), where a single dose (5 mg/kg) of lipopolysaccharide (LPS) was given intratracheally, and then the respiratory tidal volume was reduced by 40%...
December 2024: Artificial Cells, Nanomedicine, and Biotechnology
https://read.qxmd.com/read/38421440/venoarterial-extracorporeal-membrane-oxygenation-implementation-in-septic-shock-rat-model
#20
JOURNAL ARTICLE
Tianlong Wang, Mingru Zhang, Wenhao Dong, Jing Wang, Han Zhang, Yuefu Wang, Bingyang Ji
Septic shock, a global health concern, boasts high mortality rates. Research exploring the efficacy of venoarterial extracorporeal membrane oxygenation (VA-ECMO) in septic shock remains limited. Our study aimed to establish a rodent model employing VA-ECMO in septic shock rats, assessing the therapeutic impact of VA-ECMO on septic shock. Nineteen Sprague-Dawley rats were randomly assigned to sham, septic shock, and (septic shock + VA-ECMO; SSE) groups. Septic shock was induced by intravenous lipopolysaccharides, confirmed by a mean arterial pressure drop to 25-30% of baseline...
February 20, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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