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https://www.readbyqxmd.com/read/29348141/cellulase-6-and-mannanase-7-affect-cell-differentiation-and-silique-dehiscence
#1
Hanjun He, Mei Bai, Panpan Tong, Yanting Hu, Ming Yang, Hong Wu
Cellulases, hemicellulases and pectinases play important roles in fruit development and maturation, but mutants with defects in the fruit have not been reported for cellulase or hemicellulase genes. Here we report the functional characterization of cellulase gene CEL6 and hemicellulase gene MAN7 in silique development and dehiscence in Arabidopsis. These genes were found to be expressed in vegetative and reproductive organs, and their expression in the silique partially depended on the IND and ALC transcriptional factors...
January 18, 2018: Plant Physiology
https://www.readbyqxmd.com/read/29329309/time-series-sightability-modeling-of-animal-populations
#2
Althea A ArchMiller, Robert M Dorazio, Katherine St Clair, John R Fieberg
Logistic regression models-or "sightability models"-fit to detection/non-detection data from marked individuals are often used to adjust for visibility bias in later detection-only surveys, with population abundance estimated using a modified Horvitz-Thompson (mHT) estimator. More recently, a model-based alternative for analyzing combined detection/non-detection and detection-only data was developed. This approach seemed promising, since it resulted in similar estimates as the mHT when applied to data from moose (Alces alces) surveys in Minnesota...
2018: PloS One
https://www.readbyqxmd.com/read/29319126/autophagy-activation-promotes-removal-of-damaged-mitochondria-and-protects-against-renal-tubular-injury-induced-by-albumin-overload
#3
Jin Tan, Miaohong Wang, Shuling Song, Shuling Miao, Qiang Zhang
Proteinuria (albuminuria) is an important cause of aggravating tubulointerstitial injury. Previous studies have shown that autophagy activation can alleviate renal tubular epithelial cell injury caused by urinary protein, but the mechanism is not clear. Here, we investigated the role of clearance of damaged mitochondria in this protective effect. We found that albumin overload induces a significant increase in turnover of LC3-II and decrease in p62 protein level in renal proximal tubular (HK-2) cells in vitro...
January 10, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29289199/adaptive-laser-conditioning-of-reflective-thin-film-based-on-photo-thermal-lens-probe
#4
Zhichao Liu, Yi Zheng, Qinghua Zhang, Feng Pan, Yaowei Wei, Jian Wang, Qiao Xu
A novel laser conditioning (LC) concept that performs adaptive control of exposure fluence is proposed. As photo-thermal absorption effect can discover defects responsible for laser-induced damage of reflective thin film, in situ photo-thermal lens probe is introduced in conventional LC procedure to detect defects during raster-scanning. The absorptance signal is fed back to guide the adaptive control of exposure fluence. By this method, the damage risk accompanying with LC can be reduced to a rather low level...
December 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29288139/molecular-taxonomy-and-subgeneric-classification-of-tapeworms-of-the-genus-moniezia-blanchard-1891-cestoda-anoplocephalidae-in-northern-cervids-alces-and-rangifer
#5
Voitto Haukisalmi, Sauli Laaksonen, Antti Oksanen, Kimberlee Beckmen, Ali Halajian, Tetsuya Yanagida, Minoru Nakao
Phylogenetic relationships of tapeworms of the genus Moniezia Blanchard, 1891 (Cestoda, Anoplocephalidae) parasitizing the Eurasian elk Alces alces, the moose A. americanus and the reindeer/caribou Rangifer tarandus (Cervidae) were studied using DNA sequences of two mitochondrial genes (cox1 and nad1). Several isolates from domestic ruminants, representing Moniezia expansa (Rudolphi, 1810) sensu lato and M. benedeni (Moniez, 1879) sensu lato, and one unidentified isolate from an African antelope, were also included in the analysis...
December 26, 2017: Parasitology International
https://www.readbyqxmd.com/read/29287223/is-recovery-from-cannabis-use-problems-different-from-alcohol-and-other-drugs-results-from-a-national-probability-based-sample-of-the-united-states-adult-population
#6
John F Kelly, M Claire Greene, Brandon G Bergman
BACKGROUND: The policy landscape regarding the legal status of cannabis (CAN) in the US and globally is changing rapidly. Research on CAN has lagged behind in many areas, none more so than in understanding how individuals suffering from the broad range of cannabis-related problems resolve those problems, and how their characteristics and problem resolution pathways are similar to or different from alcohol [ALC] or other drugs [OTH]. Greater knowledge could inform national policy debates as well as the nature and scope of any additional needed services as CAN population exposure increases...
December 26, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29282442/impact-of-cyberknife-radiosurgery-on-overall-survival-and-various-parameters-of-patients-with-1-3-versus-%C3%A2-4-brain-metastases
#7
Judith Murovic, Victoria Ding, Summer S Han, John R Adler, Steven D Chang
Introduction This study's objective is to compare the overall survivals (OSs) and various parameters of patients with 1-3 versus ≥ 4 brain metastases post-CyberKnife radiosurgery (CKRS) (Accuray, Sunnyvale, California) alone. Methods Charts of 150 patients, from 2009-2014, treated with only CKRS for brain metastases were reviewed retrospectively for overall survival (OS) and patient, tumor, and imaging characteristics. Parameters included demographics, Eastern Cooperative Oncology Group (ECOG) performance scores, number and control of extracranial disease (ECD) sites, cause of death (COD), histology, tumor volume (TV), and post-CKRS whole brain radiotherapy (WBRT)...
October 24, 2017: Curēus
https://www.readbyqxmd.com/read/29281648/yew-taxus-intoxication-in-free-ranging-cervids
#8
Kjell Handeland, Turid Vikøren, Terje D Josefsen, Knut Madslien, Belinda Valdecanas, Silvio Uhlig
Wild ruminants, including deer species (cervids) have incorrectly been regarded as refractory to yew (Taxus) intoxication. This assumption has been based upon anecdotal observations of individual deer browsing on yew over time without apparent adverse effect. A single case of yew intoxication was reported in a free-ranging Norwegian moose (Alces alces) in 2008. The current report describes five additional cases of yew toxicosis in moose, seven in roe deer (Capreolus capreolus) and two in reindeer (Rangifer tarandus tarandus), all in Norway...
2017: PloS One
https://www.readbyqxmd.com/read/29278859/acetyl-l-carnitine-attenuates-arsenic-induced-liver-injury-by-abrogation-of-mitochondrial-dysfunction-inflammation-and-apoptosis-in-rats
#9
Vida Bodaghi-Namileh, Mohammad Reza Sepand, Ameneh Omidi, Mehdi Aghsami, Seyed Afshin Seyednejad, Sara Kasirzadeh, Omid Sabzevari
Industrial and agricultural developments in recent years have resulted in the excessive discharge of arsenic into the environment, making arsenic toxicity a major worldwide concern. Oxidative stress is considered the primary mechanism for arsenic toxicity. The main objective of this study was to evaluate acetyl-l-carnitine's (ALC) protective ability against the arsenic-induced hepatotoxicity. For this purpose, male Wistar rats were distributed randomly into 5 groups of 8 rats each: control, arsenic (5 mg/kg) and arsenic plus ALC (5 mg/kg; 100, 200, 300 mg/kg)...
December 12, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/29258374/falls-prevention-process-in-assisted-living-communities
#10
DaRae Coughlin, Susan E Nordman-Oliveira, Mary Schlaak, James H Ford
Falls are a significant issue for older adults, and many older adults who once received care in nursing homes now reside in assisted living communities (ALCs). ALC staff needs to address resident falls prevention; however, federal or state requirements or oversight are limited. This research explores falls prevention in Wisconsin ALCs in the context of the Kotter Change Model to identify strategies and inform efforts to establish a more consistent, proactive falls prevention process for ALCs. A mixed methods approach demonstrated inconsistency and variability in the use of falls risk assessments and prevention programs, which led to the development of standardized, proactive falls prevention process flowcharts...
December 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/29249975/fluoride-alters-klk4-expression-in-maturation-ameloblasts-through-androgen-and-progesterone-receptor-signaling
#11
Michael H Le, Yukiko Nakano, Dawud Abduweli Uyghurturk, Li Zhu, Pamela K Den Besten
Fluorosed maturation stage enamel is hypomineralized in part due to a delay in the removal of matrix proteins to inhibit final crystal growth. The delay in protein removal is likely related to reduced expression of kallikrein-related peptidase 4 (KLK4), resulting in a reduced matrix proteinase activity that found in fluorosed enamel. Klk4 transcription is known to be regulated in other cell types by androgen receptor (AR) and progesterone receptors (PR). In this study, we determined the possible role of fluoride in down-regulation of KLK4 expression through changes in AR and PR...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29243370/neurological-nutritional-and-alcohol-consumption-factors-underlie-cognitive-and-motor-deficits-in-chronic-alcoholism
#12
Rosemary Fama, Anne-Pascale Le Berre, Cheshire Hardcastle, Stephanie A Sassoon, Adolf Pfefferbaum, Edith V Sullivan, Natalie M Zahr
Variations in pattern and extent of cognitive and motor impairment occur in alcoholism (ALC). Causes of such heterogeneity are elusive and inconsistently accounted for by demographic or alcohol consumption differences. We examined neurological and nutritional factors as possible contributors to heterogeneity in impairment. Participants with ALC (n = 96) and a normal comparison group (n = 41) were examined on six cognitive and motor domains. Signs of historically determined subclinical Wernicke's encephalopathy were detected using the Caine et al...
December 15, 2017: Addiction Biology
https://www.readbyqxmd.com/read/29241306/combined-and-isolated-effects-of-alcohol-intake-and-one-night-of-sleep-deprivation-on-mood-states-hormonal-and-inflammatory-responses-in-healthy-male-adults-a-crossover-randomized-controlled-trial
#13
Rodrigo Rodrigues, Rodrigo de Azevedo Franke, Bruno Costa Teixeira, Rodrigo Cauduro de Oliveira Macedo, André Luiz Lopes, Álvaro Reischak-Oliveira, Bruno Manfredini Baroni, Marco Aurélio Vaz
Alcohol intake and sleep deprivation are conditions that cause changes in the physiological status. However, the relationship between biological markers and mood states is not entirely clear yet. The purpose of the study was to compare isolated and combined effects of alcohol intake and sleep deprivation on hormonal and inflammatory responses and in changes in the state of mood. Also, we intended to explain possible changes in mood states through biochemical variations using multiple stepwise regression analysis...
December 15, 2017: Chinese Journal of Physiology
https://www.readbyqxmd.com/read/29234028/the-representation-of-colored-objects-in-macaque-color-patches
#14
Le Chang, Pinglei Bao, Doris Y Tsao
An important question about color vision is how does the brain represent the color of an object? The recent discovery of "color patches" in macaque inferotemporal (IT) cortex, the part of the brain responsible for object recognition, makes this problem experimentally tractable. Here we recorded neurons in three color patches, middle color patch CLC (central lateral color patch), and two anterior color patches ALC (anterior lateral color patch) and AMC (anterior medial color patch), while presenting images of objects systematically varied in hue...
December 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/29226555/climate-warming-is-associated-with-smaller-body-size-and-shorter-lifespans-in-moose-near-their-southern-range-limit
#15
Sarah R Hoy, Rolf O Peterson, John A Vucetich
Despite the importance of body size for individual fitness, population dynamics and community dynamics, the influence of climate change on growth and body size is inadequately understood, particularly for long-lived vertebrates. Although temporal trends in body size have been documented, it remains unclear whether these changes represent the adverse impact of climate change (environmental stress constraining phenotypes) or its mitigation (via phenotypic plasticity or evolution). Concerns have also been raised about whether climate change is indeed the causal agent of these phenotypic shifts, given the length of time-series analysed and that studies often do not evaluate - and thereby sufficiently rule out - other potential causes...
December 10, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29211747/profiling-of-volatile-fragrant-components-in-a-mini-core-collection-of-mango-germplasms-from-seven-countries
#16
Li Li, Xiao-Wei Ma, Ru-Lin Zhan, Hong-Xia Wu, Quan-Sheng Yao, Wen-Tian Xu, Chun Luo, Yi-Gang Zhou, Qing-Zhi Liang, Song-Biao Wang
Aroma is important in assessing the quality of fresh fruit and their processed products, and could provide good indicators for the development of local cultivars in the mango industry. In this study, the volatile diversity of 25 mango cultivars from China, America, Thailand, India, Cuba, Indonesia, and the Philippines was investigated. The volatile compositions, their relative contents, and the intervarietal differences were detected with headspace solid phase microextraction tandem gas chromatography-mass spectrometer methods...
2017: PloS One
https://www.readbyqxmd.com/read/29208835/effects-of-fuchs-uveitis-syndrome-on-the-ultrastructure-of-the-anterior-lens-epithelium-a-transmission-electron-microscopic-study
#17
Kemal Tekin, Yasemin Ozdamar Erol, Mustafa Fevzi Sargon, Merve Inanc, Pinar Cakar Ozdal, Nilufer Berker
PURPOSE: The purpose of the study was to investigate the electron microscopic findings of the lens epithelial cells (LECs) in patients with Fuchs uveitis syndrome (FUS) who suffered from cataracts and to compare those with age-matched controls. METHODS: This study was a prospective, comparative case series. The anterior lens capsules (ALC: basement membrane and associated LECs) were taken from 12 eyes of 12 cases of FUS and ten eyes of ten control patients. The ALCs were obtained from cataract surgery and prepared for transmission electron microscopy (TEM)...
December 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29202283/brominated-flame-retardants-and-toxic-elements-in-the-meat-and-liver-of-red-deer-cervus-elaphus-wild-boar-sus-scrofa-and-moose-alces-alces-from-latvian-wildlife
#18
D Zacs, J Rjabova, L E Ikkere, K Bavrins, V Bartkevics
In order to evaluate the contamination status of terrestrial biota in Latvia, muscle and liver tissues of red deer (Cervus elaphus), wild boar (Sus scrofa), and moose (Alces alces) were analyzed for the content of polybrominated diphenyl ethers (PBDE), hexabromocyclododecane (HBCD), tetrabromobisphenol A (TBBPA), as well as cadmium and lead. The highest mean concentrations of PBDEs (46.6pgg-1 wet weight (w.w.)), cadmium (0.95mgkg-1 w.w.), and lead (0.22mgkg-1 w.w.) were observed in the tissues of moose, while the wild boar samples contained the highest levels of HBCD, with the mean concentration equal to 264pgg-1 w...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29191664/immune-reconstitution-following-autologous-stem-cell-transplantation-in-patients-with-high-risk-neuroblastoma-at-the-time-of-immunotherapy
#19
Michele L Nassin, Elitsa Nicolaou, Sandeep Gurbuxani, Susan L Cohn, John M Cunningham, James L LaBelle
Outcomes for patients with high-risk neuroblastoma (HR-NBL) are significantly improved with the addition of immunotherapy (dinutuximab + cytokines) following autologous hematopoietic stem cell transplantation (autoHSCT). We hypothesized that the immune system is not fully reconstituted at the initiation of immunotherapy. To test this hypothesis, we evaluated hematologic and immune subsets in thirty-four patients with HR-NBL before and following autoHSCT(s). We found that absolute T-, B-, and NK cell counts at the time of immunotherapy were below normal in 80% of patients...
November 27, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29189995/acetyl-l-carnitine-attenuates-arsenic-induced-oxidative-stress-and-hippocampal-mitochondrial-dysfunction
#20
Hedieh Keshavarz-Bahaghighat, Mohammad Reza Sepand, Mohammad Hossein Ghahremani, Mehdi Aghsami, Nima Sanadgol, Ameneh Omidi, Vida Bodaghi-Namileh, Omid Sabzevari
Augmentation of mitochondrial oxidative stress through activating a series of deadly events has implicated as the main culprit of arsenic toxicity and therapeutic approaches based on improving mitochondrial function hold a great promise for attenuating the arsenic-induced toxicity. Acetyl-L-carnitine (ALC) through balancing the coenzyme A (CoA)/acyl-CoA ratio plays an important role in mitochondrial metabolism and thereby can help protect hippocampal neurons from oxidative damage. In the present study, we aimed to explore the effect of arsenic interactions on the mitochondrial function in the hippocampus of rats...
November 30, 2017: Biological Trace Element Research
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