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orbital pseudotumor

Promil Jain, Rajeev Sen, Nisha Sharma, Shilpi Bhargava, Virender Singh
Tumefactive fibroinflammatory lesions (TFLs) are rare idiopathic benign fibrosclerosing lesions that clinically simulate a malignancy. TFLs are seen more frequently in males between 10 and 74 years of age. The usual site of involvement is the head and neck region, but rarely the extremities may be involved. Coexisting fibrosclerotic processes have been reported including retroperitoneal fibrosis, sclerosing cholangitis, sclerosing mediastinal fibrosis, and orbital pseudotumors. The etiology of this poorly understood entity remains unknown...
March 2017: Iranian Journal of Medical Sciences
A K Tanon, C Assouan, E Anzouan-Kacou, D N'guessan, A Salami, S Boni, E Konan
INTRODUCTION: The invasive fungal infection of the maxillary sinus is a rare and serious disease generally favored by immunosuppression. We report an exceptional case of pseudotumoral invasive fungal infection of the maxillary sinus in an immunocompetent patient. OBSERVATION: A 32-year-old patient consulted for labial and left temporal swelling associated with proptosis and chemosis that has been developing for 18 months. The scanner objectified a filling of the left maxillary sinus, and the ipsilateral orbital cavity, and the surrounding muscles...
March 20, 2017: Journal de Mycologie Médicale
Rachna Meel, Rebika Dhiman, Meenakshi Wadhwani, Seema Kashyap, Sanjay Sharma, Ajay Gogia
PURPOSE: Natural killer T-cell lymphoma (NKTL) is a highly malignant tumor that typically arises in the nose and/or paranasal sinuses. Isolated orbital involvement by NKTL is extremely rare, and only few case reports exist in the literature. Herein, we report a case of primary orbital NKTL in a young patient who showed very good response to chemotherapy with the SMILE regimen. METHODS: A 28-year-old healthy female presented to us with epiphora and fullness of the lower eyelid...
January 2017: Ocular Oncology and Pathology
Iman Aouidad, Pierre Schneider, Mathieu Zmuda, Jeremy Gottlieb, Manuelle Viguier
No abstract text is available yet for this article.
March 1, 2017: JAMA Dermatology
M Leo, F Maggi, G R Dottore, G Casini, P Mazzetti, M Pistello, S Sellari-Franceschini, M Nardi, P Vitti, C Marcocci, M Marinò
OBJECTIVE: One of the hypotheses on the pathogenesis of autoimmune diseases, including Graves' disease (GD) and Graves' orbitopathy (GO), involves bacterial or viral infections. Recently, Epstein-Barr virus (EBV) has been proposed to play a role in the pathogenesis of idiopathic orbital inflammatory pseudotumor (IOIP) in Asians. The aim of the present study was to investigate the possible association of GO with EBV infection/exposure, as compared with IOIP, using serum and tissue samples, as well as primary cultures of orbital fibroblasts...
December 16, 2016: Journal of Endocrinological Investigation
Omer Doron, Jose E Cohen, Moshe Gomori, Sergey Spektor
Carotid ophthalmic aneurysms constitute 0.9-6.5% of the aneurysms of the ICA with up to 20% of the cases presenting with visual symptoms. We report a case of an adult woman, presented with chronic headaches and protracted visual alterations progressing to left eye amaurosis. Neuroradiological exams, revealed a giant partially thrombosed carotid ophthalmic aneurysm extending anteriorly, causing pseudotumoral spheno-orbital bone erosion. The patient underwent surgical clipping, evacuation of the thrombotic mass and decompression of the optic pathways with rapid recovery of the vision...
February 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
María Rico, José Bernardino Díaz-López, Jorge Peña, Pedro Oliva-Nacarino
Orbital inflammatory pseudotumor is a rare complication of systemic lupus erythematosus. It may present a challenge for differential diagnosis, especially in the context of treatment with hydroxychloroquine, although dosage and duration of the treatment may guide us. Although high antibody titers can be found, this is not specific.
November 2016: Clinical Case Reports
Antonio Augusto V Cruz, Eliza V C Alves-Ferreira, Gherusa Milbratz-Moré, Fernando Chahud, Patricia C Ruy, Maria Irma Seixas Duarte, Angela Kaysel Cruz
Orbital biopsy of nonspecific orbital inflammation, commonly referred to as "orbital pseudotumor," typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein, we report a patient with a positive history of mucocutaneous leishmaniasis who presented with an orbital mass with a histological profile of idiopathic orbital inflammation. Immunohistochemical and molecular analysis of the orbital specimens demonstrated that the orbital inflammation was associated with the presence of antigens of Leishmania braziliensis and DNA from the parasite...
January 11, 2017: American Journal of Tropical Medicine and Hygiene
Jianhua Yan
PURPOSE/BACKGROUND: To report a rare patient with idiopathic orbital inflammatory pseudotumor showing obvious bone erosion of the orbital wall. METHODS: Clinical features and imaging findings, orbital surgery, and histopathological examination are presented. RESULTS: A 56-year-old Chinese man showed a gradually growing unilateral proptosis of the left eye for 6 months. Visual acuity, intraocular pressure, anterior segment, and fundi were normal in both eyes...
October 2016: Journal of Craniofacial Surgery
Ryuya Hashimoto, Michihiro Uchiyama, Takatoshi Maeno
BACKGROUND: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare, highly malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose tissue. No case of SPTCL with the earliest symptoms occurring in the eye region has been reported. We report a case of SPTCL complicated by eyelid swelling. CASE PRESENTATION: A 19-year-old Japanese man presented with worsening left eyelid swelling. The patient's best-corrected visual acuity (BCVA) was 0...
July 20, 2016: BMC Ophthalmology
Rodrigo Carrasco-Moro, Juan Martínez-San Millán, Héctor Pian
The inflammatory pseudotumour (IPT) is a non-neoplastic entity of unknown origin, and is characterised by a proliferation of connective tissue and a polyclonal inflammatory infiltrate. Central nervous system involvement is uncommon, and usually represents a diagnostic and therapeutic challenge even for the experienced clinician. This reports deals with the case of a 56year-old woman diagnosed with a giant, infiltrating mass centred in the left cavernous sinus, who had a rapid clinical and radiological response to steroid therapy...
July 12, 2016: Neurocirugía
Benjamin Misselwitz, Jana Epprecht, Joachim Mertens, Luc Biedermann, Michael Scharl, Eugenia Haralambieva, Andreas Lutterotti, Konrad P Weber, Beat Müllhaupt, Karla Chaloupka
Hepatitis C is frequently accompanied by immune-related extrahepatic manifestations affecting the skin, kidneys, central and peripheral nervous system and exocrine glands. We present the case of a 40-year-old man with left-sided ptosis, exophthalmos and headache. MRI demonstrated left-sided orbital pseudotumor with lacrimal and retro-orbital contrast enhancement extending to the cavernous sinus and the vestibulocochlear nerve. Immunological tests of serum and cerebrospinal fluid identified hepatitis C virus (HCV) as a potential causative agent but did not indicate any additional infectious, malignant or immunological disorder...
January 2016: Case Reports in Gastroenterology
Jahangir Ahmed Afridi, Faisal Manzoor, Kamran Ashfaq Ahmed Butt, Sarfraz Janjua
Inflammatory pseudotumor is a solid fibro-inflammatory tumor that clinically mimics a neoplastic lesion. Inflammatory pseudotumor is usually found in the orbits and lungs, but rarely in the sinonasal area. Presence of pseudotumor in nasal cavity is even scarce and there are only a few reports to date. We present a case of pseudotumor involving the nasal tip area in an adult female mimicking as a slowly enlarging mass.
June 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Akihiro Nakamura, Tomoya Miyamura, Eiichi Suematsu
No abstract text is available yet for this article.
2016: Internal Medicine
María Costales, Fernando López, Andrés Coca, José Luis Llorente
No abstract text is available yet for this article.
January 2017: Acta Otorrinolaringológica Española
Jing Li, Xin Ge, Jian-Min Ma
AIM: To determine the clinical features of the dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor and its relationship with paranasal sinusitis. METHODS: A retrospective analysis of 46 patients who received surgical treatment at the Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University for the dacryoadenitis subtype of idiopathic orbital inflammatory pseudotumor from October 2010 to December 2012. Each patient underwent magnetic resonance imaging (MRI) of the orbits and the 4 paranasal sinuses...
2016: International Journal of Ophthalmology
Krzysztof Oles, Jacek Sładzień, Krzysztof Bartuś, Joanna Leszczyńska, Emila Bojanowska, Łukasz Krakowczyk, Joanna Mika
Thanks to detailed studies conducted in recent years, a new disease syndrome was identified in 2001. It is known as a IgG4-related disease and its differentiation is based on the analysis of IgG4 levels in the affected tissues. The IgG4-related disease is considered to be a generalized pathological process involving a wide spectrum of various disorders that may affect distant organs. Orbital IgG4-related disease is a recently reported issue that may prove important for the elucidation of the etiology of idiopathic, lymphoplasmacytic or fibrotic disorders of various organs, including the orbits...
June 2016: Pharmacological Reports: PR
Avni Patel, Bobeck S Modjtahedi, Suzanne K Freitag, Lucia Sobrin, Melanie A Kazlas
Idiopathic orbital inflammation or orbital pseudotumor is rare in the pediatric population and may present with ocular findings not normally seen in the adult population. The authors report the case of a 14-year-old boy with idiopathic orbital inflammation who presented with bilateral panuveitis to highlight the features that make this diagnosis more difficult in the pediatric population.
April 23, 2016: Journal of Pediatric Ophthalmology and Strabismus
Jing Li, Jian-Min Ma, Xin Ge
AIM: To explore the role of IgG4 serology in identifying common orbital lymphoproliferative disorders. METHODS: Eighty-one patients with orbital lymphoproliferative diseases were treated in the Department of Ocular Oncology, Beijing Tongren Hospital, Capital Medical University between September 2010 and December 2012. Serum IgG4 levels were measured in 46 cases of idiopathic orbital inflammatory pseudotumor (IOIP), 17 benign lymphoepithelial lesion (BLEL), 12 cases of orbital mucosa-associated lymphoid tissue (MALT), and 6 cases of diffuse large B-cell lymphoma (DLBL) using immuno-scatter turbidmetry (ISTM)...
2016: International Journal of Ophthalmology
Enrico Tedeschi, Lorenzo Ugga, Ferdinando Caranci, Francesca Califano, Sirio Cocozza, Giacomo Lus, Arturo Brunetti
BACKGROUND: Orbital inflammatory pseudotumor is a rare inflammatory condition of unknown cause that may extend intracranially, usually as a dural-based infiltrate. Here we report the first case of orbital pseudotumor presenting with intra-axial Magnetic Resonance Imaging (MRI) changes. CASE PRESENTATION: A 57-year-old white female, with a 3-month history of headache and right palpebral edema, presented with marked right temporal lobe edema with ominous MRI appearance, and ipsilateral alterations of orbital and periorbital structures...
2016: BMC Neurology
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