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https://www.readbyqxmd.com/read/29040800/ocriplasmin-for-symptomatic-vitreomacular-adhesion
#1
REVIEW
James E Neffendorf, Varo Kirthi, Edward Pringle, Timothy L Jackson
BACKGROUND: Symptomatic vitreomacular adhesion (sVMA) is a recognised cause of visual loss and by tradition has been managed by pars plana vitrectomy (PPV). A less invasive alternative to surgery in some people is enzymatic vitreolysis, using an intravitreal injection of ocriplasmin. OBJECTIVES: To assess the efficacy and safety of ocriplasmin compared to no treatment, sham or placebo for the treatment of sVMA. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Trials Register) (2017, Issue 1), MEDLINE Ovid (1946 to 24 February 2017), Embase Ovid (1947 to 24 February 2017), PubMed (1946 to 24 February 2017), the ISRCTN registry (www...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29039969/clinical-outcomes-and-failure-rates-of-osteochondral-allograft-transplantation-in-the-knee-a-systematic-review
#2
Filippo Familiari, Mark E Cinque, Jorge Chahla, Jonathan A Godin, Morten Lykke Olesen, Gilbert Moatshe, Robert F LaPrade
BACKGROUND: Cartilage lesions are a significant cause of morbidity and impaired knee function; however, cartilage repair procedures have failed to reproduce native cartilage to date. Thus, osteochondral allograft (OCA) transplantation represents a 1-step procedure to repair large chondral defects without the donor site morbidity of osteochondral autograft transplantation. PURPOSE: To perform a systematic review of clinical outcomes and failure rates after OCA transplantation in the knee at a minimum mean 2 years' follow-up...
October 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29036793/clinical-relevance-of-early-sublingual-microcirculation-monitoring-in-septic-shock-patients
#3
Nivin Sharawy, Reham Mahrous, Sara Whynot, Ronald George, Christian Lehmann
INTRODUCTION: Although microcirculation dysfunction plays unique role in septic shock, translation of microcirculation to clinical practices is limited by current semi-quantities analysis and unclear clinical relevance of microcirculation monitoring. Our aim was to critically evaluate the characteristic nature and relevant clinical important of microcirculation. EVIDENCE ACQUISITION: Pubmed (2000 to August 2015) were searched to identify observation, case-control, intervention and randomized clinical studies evaluating the relationship between microcirculation alterations and mortality, morbidity and drug responses...
October 7, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29035966/effectiveness-of-rifampicin-chemoprophylaxis-in-preventing-leprosy-in-patient-contacts-a-systematic-review-of-quantitative-and-qualitative-evidence
#4
Silvana Margarida Benevides Ferreira, Tatiana Yonekura, Eliane Ignotti, Larissa Bertacchini de Oliveira, Juliana Takahashi, Cassia Baldini Soares
BACKGROUND: Individuals in contact with patients who have leprosy have an increased risk of disease exposure, which reinforces the need for chemoprophylactic measures, such as the use of rifampicin. OBJECTIVES: The objective of the review was to synthesize the best available evidence regarding the effectiveness of rifampicin chemoprophylaxis for contacts with patients with leprosy, and to synthesize the best available evidence on the experience and acceptability of rifampicin chemoprophylaxis as reported by the contacts and health professionals involved in the treatment of leprosy or Hansen's disease...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035965/effectiveness-of-bedrails-in-preventing-falls-among-hospitalized-older-adults-a-systematic-review
#5
Paulo Marques, Carmen Queirós, João Apóstolo, Daniela Cardoso
BACKGROUND: Falls are a major problem today affecting adults of any age, but the elderly are a population that is more susceptible to falls. Falls are the leading cause of injury or death among older adults. Hospitalized older people are particularly vulnerable to falls. Falls cause direct injuries (minor injuries, severe wounds of the soft tissues and bone fractures) to patients and increased length of stay. The prevention of falls is commonly considered an indicator of the quality of care...
October 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29035425/inhaled-versus-systemic-corticosteroids-for-the-treatment-of-bronchopulmonary-dysplasia-in-ventilated-very-low-birth-weight-preterm-infants
#6
REVIEW
Sachin S Shah, Arne Ohlsson, Henry L Halliday, Vibhuti S Shah
BACKGROUND: This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia (BPD) is a serious and common problem among very low birth weight infants, despite the use of antenatal steroids and postnatal surfactant therapy to decrease the incidence and severity of respiratory distress syndrome. Due to their anti-inflammatory properties, corticosteroids have been widely used to treat or prevent BPD...
October 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29034533/efficacy-tolerability-and-safety-of-cannabis-based-medicines-for-chronic-pain-management-an-overview-of-systematic-reviews
#7
REVIEW
W Häuser, F Petzke, M-A Fitzcharles
Medicinal cannabis has already entered mainstream medicine in some countries. This systematic review (SR) aimed at evaluating the efficacy, acceptability and safety of cannabis-based medicines for chronic pain management. Qualitative systematic review of SRs of randomized controlled trials with cannabis-based medicines for chronic pain management. The Cochrane databases of SRs, Database of Abstracts of Reviews of Effects and PubMed were searched for SR published in the period January 2009 to January 2017. Assessment of the methodological quality of SR was performed by the AMSTAR checklist...
October 15, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29033570/atypical-depression-current-perspectives
#8
REVIEW
Dorota Łojko, Janusz K Rybakowski
The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with atypical feature is present for both diagnostic groups, that is, depressive disorders and bipolar and related disorders. This specifier includes mood reactivity, hyperphagia, hypersomnia, leaden paralysis, and interpersonal rejection sensitivity...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29032354/exercise-for-hand-osteoarthritis-a-cochrane-systematic-review
#9
Nina Østerås, Ingvild Kjeken, Geir Smedslund, Rikke H Moe, Barbara Slatkowsky-Christensen, Till Uhlig, Kåre Birger Hagen
OBJECTIVE: To assess the benefits and harms of exercise compared with other interventions, including placebo or no intervention, in people with hand osteoarthritis (OA). METHODS: Systematic review using Cochrane Collaboration methodology. Six electronic databases were searched up until September 2015. INCLUSION CRITERIA: randomized or controlled clinical trials comparing therapeutic exercise versus no exercise, or comparing different exercise programs...
October 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/29032130/nonmedical-treatments-of-vocal-fold-nodules-a-systematic-review
#10
REVIEW
Banafshe Mansuri, Seyed Abolfazl Tohidast, Nasibe Soltaninejad, Mohammad Kamali, Leila Ghelichi, Hadi Azimi
OBJECTIVES: The aim of the present systematic review was to investigate the nonmedical treatments of vocal fold nodules (VFNs). STUDY DESIGN: The present study is a systematic review. METHODS: The following electronic databases were searched from inception until August 2016: PubMed, Scopus, ScienceDirect, Ovid, ISI (Web of Sciences), Cochrane, PsychINFO, The Cochrane Central Register of Controlled Trials, and Google Scholar. Reference lists of included articles were evaluated for additional data...
October 11, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29032016/neuropsychological-outcomes-following-paediatric-temporal-lobe-surgery-for-epilepsies-evidence-from-a-systematic-review
#11
REVIEW
Alice E Flint, Mitch Waterman, Grace Bowmer, Gayatri Vadlamani, Paul Chumas, Matthew C H J Morrall
OBJECTIVE: The systematic review aimed to assess the neuropsychological outcomes of temporal lobe resections for epilepsy in children. Additional objectives included determining whether earlier age at surgery leads to better neuropsychological outcomes; the relationships between and predictors of these outcomes. METHODS: Using advanced search terms, a systematic review of electronic databases was conducted, comprising MEDLINE, Embase, PsycINFO, Global Health, Web of Science and CINAHL...
September 19, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29030329/effect-of-a-website-that-presents-patients-experiences-on-self-efficacy-and-patient-competence-of-colorectal-cancer-patients-web-based-randomized-controlled-trial
#12
Jürgen M Giesler, Bettina Keller, Tim Repke, Rainer Leonhart, Joachim Weis, Rebecca Muckelbauer, Nina Rieckmann, Jacqueline Müller-Nordhorn, Gabriele Lucius-Hoene, Christine Holmberg
BACKGROUND: Patients often seek other patients' experiences with the disease. The Internet provides a wide range of opportunities to share and learn about other people's health and illness experiences via blogs or patient-initiated online discussion groups. There also exists a range of medical information devices that include experiential patient information. However, there are serious concerns about the use of such experiential information because narratives of others may be powerful and pervasive tools that may hinder informed decision making...
October 13, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29029684/validation-of-the-three-web-quality-dimensions-of-a-minimally-invasive-surgery-e-learning-platform
#13
Juan Francisco Ortega-Morán, J Blas Pagador, Luisa Fernanda Sánchez-Peralta, Patricia Sánchez-González, José Noguera, Daniel Burgos, Enrique J Gómez, Francisco M Sánchez-Margallo
INTRODUCTION: E-learning web environments, including the new TELMA platform, are increasingly being used to provide cognitive training in minimally invasive surgery (MIS) to surgeons. A complete validation of this MIS e-learning platform has been performed to determine whether it complies with the three web quality dimensions: usability, content and functionality. METHODS: 21 Surgeons participated in the validation trials. They performed a set of tasks in the TELMA platform, where an e-MIS validity approach was followed...
November 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29029675/a-meta-analysis-of-compassion-based-interventions-current-state-of-knowledge-and-future-directions
#14
REVIEW
James N Kirby, Cassandra L Tellegen, Stanley R Steindl
OBJECTIVE: Scientific research into compassion has burgeoned over the past 20 years and interventions aiming to cultivate compassion towards self and others have been developed. This meta-analysis examined the effects of compassion-based interventions on a range of outcome measures. METHOD: Twenty-one randomized controlled trials (RCTs) from the last 12 years were included in the meta-analysis, with data from 1,285 participants analyzed. Effect sizes were standardized mean differences calculated using the difference in pre-post change in the treatment group and control group means, divided by the pooled pre-intervention standard deviation...
November 2017: Behavior Therapy
https://www.readbyqxmd.com/read/29029557/do-exercise-interventions-improve-participation-in-life-roles-in-older-adults-a-systematic-review-and-meta-analysis
#15
REVIEW
Marla K Beauchamp, Annemarie Lee, Rachel F Ward, Samantha M Harrison, Paul A Bain, Roger S Goldstein, Dina Brooks, Jonathan F Bean, Alan M Jette
Background: The World Health Organization recognizes participation in meaningful life roles as a key component of health. However, the evidence base for interventions to improve participation remains inconclusive. In particular, whether exercise interventions improve participation in life roles is unclear. Purpose: The aim of this review was to evaluate the effect of physical exercise interventions on participation in life roles in older adults residing in the community...
October 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29027648/prevention-of-type-2-diabetes-with-the-chinese-herbal-medicine-tianqi-capsule-a-systematic-review-and-meta-analysis
#16
REVIEW
Bing Pang, Ying Zhang, Jing Liu, Li-Sha He, Yu-Jiao Zheng, Feng-Mei Lian, Xiao-Lin Tong
INTRODUCTION: Prevention of the rapid growth in incidence of type 2 diabetes (T2DM) is a big challenge for clinicians. In China, many trials have indicated that Tianqi capsule, which contains several Chinese herbal medicines as part of a large healing system called traditional Chinese medicine, could decrease the incidence of T2DM. The review assessed the effectiveness of Tianqi capsule in prevention of T2DM. METHODS: Seven electronic databases were searched to identify eligible trials published from the inception of the databases up until May 1, 2017...
October 13, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29026933/measurement-properties-of-the-most-commonly-used-foot-and-ankle-specific-questionnaires-the-ffi-faos-and-faam-a%C3%A2-systematic-review
#17
REVIEW
I N Sierevelt, R Zwiers, W Schats, D Haverkamp, C B Terwee, P A Nolte, G M M J Kerkhoffs
PURPOSE: In the foot and ankle literature, a wide range of patient-reported outcome measures (PROMs) is used, however, consensus as to which PROMs are preferred is lacking. Selection of a PROM is among other reasons, often based on measurement properties without considering the methodological quality of the studies that evaluate these measurement properties. The aim of current study was first to identify the most frequently used foot and ankle-specific PROMs in recent orthopaedic foot and ankle literature, and second to conduct a systematic review to synthesize and critically appraise the measurement properties of these PROMS...
October 12, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29026889/study-design-of-real-world-evidence-for-treatment-of-hyperkalemia-in-the-emergency-department-reveal-ed-a-multicenter-prospective-observational-study
#18
Zubaid Rafique, Mikhail Kosiborod, Carol L Clark, Adam J Singer, Stewart Turner, Joseph Miller, Douglas Char, W Frank Peacock
OBJECTIVE: Hyperkalemia affects up to 10% of hospitalized patients and, if left untreated, can lead to serious cardiac arrhythmias or death. Although hyperkalemia is frequently encountered in the emergency department (ED), and is potentially life-threatening, standard of care for the treatment is poorly defined, with little supporting evidence. The main objectives of this observational study are to define the overall burden of hyperkalemia in the ED setting, describe its causes, the variability in treatment patterns and characterize the effectiveness and safety of ED standard of care therapies used in the United States...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29026838/tumor-necrosis-factor-alpha-antibodies-in-fistulizing-crohn-s-disease-an-updated-systematic-review-and-meta-analysis
#19
REVIEW
Pardis Zaboli, Mohammad Abdollahi, Shilan Mozaffari, Shekoufeh Nikfar
Medical treatment for fistulizing Crohn's disease (FCD) is changing rapidly over the time by the introduction of novel therapeutic medicines, while no global consensus is available. This study aims to accomplish a systematic review and meta-analysis on the efficacy of tumor necrosis factor-alpha antibodies (anti-TNF-α antibodies) versus placebo in FCD. A systematic review of published literature was carried out till December 2016, and a meta-analysis of identified studies was done. Data have been explored from PubMed, Scopus, Cochrane Library Database, and Web of Science...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29025197/adenosine-versus-intravenous-calcium-channel-antagonists-for-supraventricular-tachycardia
#20
REVIEW
Samer Alabed, Ammar Sabouni, Rui Providencia, Edmond Atallah, Mohammed Qintar, Timothy Ja Chico
BACKGROUND: People with supraventricular tachycardia (SVT) frequently are symptomatic and present to the emergency department for treatment. Although vagal manoeuvres may terminate SVT, they often fail, and subsequently adenosine or calcium channel antagonists (CCAs) are administered. Both are known to be effective, but both have a significant side effect profile. This is an update of a Cochrane review previously published in 2006. OBJECTIVES: To review all randomised controlled trials (RCTs) that compare effects of adenosine versus CCAs in terminating SVT...
October 12, 2017: Cochrane Database of Systematic Reviews
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