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https://www.readbyqxmd.com/read/28719872/health-related-quality-of-life-in-patients-undergoing-lumbar-total-disc-replacement-a-comparison-with-the-general-population
#1
Clavel Pablo, Gheorghe Ungureanu, Catalá Ignasi, Guillermo Montes, Xavier Málaga, Moisés Ríos
OBJECTIVES: In up to half of the cases, low back pain (LBP) is thought to be related to a degeneration of the lumbar disc. Lumbar total disc replacement (LTDR) emerged as an alternative to fusion, but its use and indications are still subject to debate. The purpose of this paper was to compare Health-related Quality of life (HRQOL) in patients undergoing LTDR for one or two-level degenerative disc disease (DDD) with the paired age and gender general population values and to assess functional disability and residual pain at one year after the surgical procedure...
July 11, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28719083/subtypes-of-personality-and-locus-of-control-in-bariatric-patients-and-their-effect-on-weight-loss-eating-disorder-and-depressive-symptoms-and-quality-of-life
#2
Carolin Peterhänsel, Katja Linde, Birgit Wagner, Arne Dietrich, Anette Kersting
The present study subdivided personality types in a bariatric sample and investigated their impact on weight loss and psychopathology 6 and 12 months after surgery. One hundred thirty participants answered questionnaires on personality (NEO-FFI), 'locus of control' (IPC), depression severity (BDI-II), eating disorder psychopathology (EDE-Q), and health-related quality of life (HRQoL; SF-12). K-means cluster analyses were used to identify subtypes. Two subtypes emerged: an 'emotionally dysregulated/undercontrolled' cluster defined by high neuroticism and external orientation and a 'resilient/high functioning' cluster with the reverse pattern...
July 18, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28718189/-health-related-quality-of-life-self-esteem-and-health-behaviour-on-average-6-years-after-an-obesity-outpatient-lifestyle-program
#3
Ingo Menrath, Angelika Gminder, Olaf Hiort, Ute Thyen
Background Multimodal programs focusing on weight reduction are recommended in guidelines for the treatment of obese children. However, studies investigating the effects of such programs over time are still missing; there is especially a lack of studies considering longer periods after treatment. In the present study, adolescents' bodyweight, health-related quality of life (HRQoL), self-esteem and health behavior were assessed before and directly after the treatment as well as 3 years after the treatment. Methods Between 2005 and 2009 84 children and adolescents took part in a 10-month, multimodal training programme...
July 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28717959/-development-and-validation-of-the-stapesplasty-outcome-test%C3%A2-25-spot-25
#4
S Lailach, T Schenke, I Baumann, H Walter, M Praetorius, T Beleites, T Zahnert, M Neudert
BACKGROUND: Otosclerosis affects health-related quality of life (HRQOL). Until now, measurements have only been performed using audiometric data or non-validated quality of life questionnaires. OBJECTIVE: The objective of this study was to develop the first validated disease-specific HRQOL measuring instrument to determine HRQOL in otosclerosis. MATERIALS AND METHODS: After sequential analysis and item reduction of the initial Stapesplasty Outcome Test 47 (SPOT-47), the SPOT-25 was validated prospectively on 52 otosclerosis patients undergoing stapes surgery...
July 17, 2017: HNO
https://www.readbyqxmd.com/read/28716486/the-impact-of-a-peer-support-group-for-children-with-rheumatic-heart-disease-in-uganda
#5
Amy Scheel, Andrea Beaton, Emmy Okello, Chris T Longenecker, Isaac Omara Otim, Peter Lwabi, Craig Sable, Allison R Webel, Twalib Aliku
OBJECTIVE: To assess the impact of a peer-support group on knowledge, quality of life, and social support for children with rheumatic heart disease (RHD). METHODS: Children diagnosed with RHD and receiving 4-weekly injectable penicillin were invited to participate in a monthly support group for 6 months. Pre- and post-intervention assessments included a baseline RHD knowledge assessment, a measure of health related quality of life (HRQOL) (PedsQLTM4.0), and a measure of social support (Hawthorne Friendship Scale)...
July 11, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28716237/long-term-follow-up-on-quality-of-life-and-its-relationship-to-motor-and-cognitive-functions-in-parkinson-s-disease-after-deep-brain-stimulation
#6
Tatsuya Yamamoto, Tomoyuki Uchiyama, Yoshinori Higuchi, Masato Asahina, Shigeki Hirano, Yoshitaka Yamanaka, Liu Weibing, Satoshi Kuwabara
INTRODUCTION: We aimed to examine temporal changes in health-related quality of life (HRQOL) and its relationship with motor and cognitive functions in patients with Parkinson's disease (PD) after subthalamic nucleus deep brain stimulation (STN-DBS). METHODS: In total, 31 patients with PD were enrolled in this study (mean age: 66.7±0.9years; mean disease duration: 11.6±3.7years). Participants completed the Unified Parkinson's Disease Rating Scale and the Parkinson's Disease Questionnaire-39...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28716065/the-validity-of-the-sf-12-and-sf-6d-instruments-in-people-living-with-hiv-aids-in-kenya
#7
Anik R Patel, Richard T Lester, Carlo A Marra, Mia L van der Kop, Paul Ritvo, Lidia Engel, Sarah Karanja, Larry D Lynd
BACKGROUND: Health-related quality of life (HRQoL) and health state utility value (HSUV) measurements are vital components of healthcare clinical and economic evaluations. Accurate measurement of HSUV and HRQoL require validated instruments. The 12-item Short-Form Health Survey (SF-12) is one of few instruments that can evaluate both HRQoL and HSUV, but its validity has not been assessed in people living with HIV/AIDS (PLWHA) in east Africa, where the burden of HIV is high. METHODS: This cross-sectional study used baseline data from a randomized trial involving PLWHA in Kenya...
July 17, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28715354/validation-of-eq-5d-and-15d-in-the-assessment-of-health-related-quality-of-life-in-chronic-pain
#8
Pekka Vartiainen, Pekka Mäntyselkä, Tarja Heiskanen, Nora Hagelberg, Seppo Mustola, Heli Forssell, Hannu Kautiainen, Eija Kalso
Chronic pain has a significant impact on quality of life. Measurement of health-related quality of life (HRQoL) is essential in the assessment of pain management outcomes, but different instruments have produced varying results. We assessed the validity of 2 HRQoL instruments, EuroQol 5 dimensions questionnaire (EQ-5D) and 15-dimensional health-related quality of life measure (15D), in patients with challenging chronic pain. Three hundred ninety-one chronic noncancer pain patients referred to tertiary pain clinics completed EQ-5D, 15D, and a broad set of questionnaires mapping socioeconomic factors, self-rated health, pain intensity and interference, depression, pain acceptance, pain-related anxiety, and sleep...
August 2017: Pain
https://www.readbyqxmd.com/read/28713797/health-related-quality-of-life-after-pediatric-liver-transplantation-a-qualitative-analysis-of-the-perspectives-of-health-care-providers
#9
Mar Miserachs, David B Nicholas, Anthony R Otley, Vicky Lee Ng
With improved survival outcomes after pediatric liver transplantation (LT), health-related quality of life (HRQoL) is an important outcome metric. Understanding the elements contributing to HRQoL after LT in children would enable more targeted strategies towards optimizing best outcomes. This qualitative study aimed to explore health care providers (HCP) perceptions about HRQoL after pediatric LT. Thirteen experienced HCP participated in two focus group discussions. Data analysis via a thematic analysis approach revealed 4 major themes: "LT as a facilitator of better HRQoL," "coping and adapting to LT," "living with a transplanted liver," and "the family context...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28712159/association-of-the-cardiometabolic-staging-system-with-individual-engagement-and-quality-of-life-in-the-us-adult-population
#10
Sandra A Tsai, Lan Xiao, Nan Lv, Ying Liu, Jun Ma
OBJECTIVE: The aim of this study was to examine the relationships of Cardiometabolic Disease Staging (CMDS), a validated five-stage system for assessing risk for diabetes, cardiovascular mortality, and all-cause mortality, with measures of individual engagement and health-related quality of life (HRQOL) in the US adult population. METHODS: Data from the 2011-2014 National Health and Nutrition Examination Survey were used to derive the CMDS stages, five participant engagement measures, and four HRQOL measures among adult participants ≥ 40 years of age...
July 16, 2017: Obesity
https://www.readbyqxmd.com/read/28711372/patient-reported-outcomes-in-optimizing-myeloma-patients-health-related-quality-of-life
#11
REVIEW
Tracy A King, M T King, K J White
OBJECTIVE: To review the current state of evidence for the use of patient-reported outcomes (PROs) and health-related quality of life (HRQoL) in optimizing best supportive care for patients with multiple myeloma (MM). DATA SOURCES: Peer-reviewed journal articles, research reports, state of the science papers, and clinical guidelines. CONCLUSION: The diagnosis and treatment of MM negatively impacts an individual's HRQoL. Validated self-report tools that assess HRQoL and other PROs provide an insight into how the treatment or disease is impacting the individual, enabling early recognition of physical and emotional concerns...
July 12, 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28710895/erectile-function-after-stereotactic-body-radiotherapy-for-localized-prostate-cancer
#12
Robert T Dess, Holly E Hartman, Nima Aghdam, William C Jackson, Payal D Soni, Ahmed E Abugharib, Simeng Suy, Neil B Desai, Zachary S Zumsteg, Rohit Mehra, Todd M Morgan, Felix Y Feng, Daniel A Hamstra, Matthew J Schipper, Sean P Collins, Daniel E Spratt
OBJECTIVE: To elucidate the functional erection rate following prostate stereotactic body radiotherapy (SBRT) and to develop a comprehensive prognostic model of outcomes following treatment. PATIENTS AND METHODS: Between 2008 and 2013, 373 consecutive men with localized prostate cancer were treated with SBRT at a single academic institution as part of a prospective clinical trial or prospective registry. Prospective longitudinal patient-reported quality of life (HRQOL) was collected using the Expanded Prostate Cancer Index Composite (EPIC-26)...
July 15, 2017: BJU International
https://www.readbyqxmd.com/read/28709437/profile-and-predictors-of-health-related-quality-of-life-among-type-ii-diabetes-mellitus-patients-in-quetta-city-pakistan
#13
Qaiser Iqbal, Noman Ul Haq, Sajid Bashir, Mohammad Bashaar
BACKGROUND: This study aims to assess the profile and predictors of Health-Related Quality of Life (HRQoL) in Type II Diabetes Mellitus (T2DM) patients in Quetta, Pakistan. METHODS: The study was designed as a questionnaire based, cross sectional analysis. 300 Type II diabetic patients attending public and private hospitals were targeted for data collection. In addition to demographic and disease related information, Euroqol Quality of Life was used to measure HRQoL...
July 14, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28708279/population-based-reference-values-for-the-european-organization-for-research-and-treatment-of-cancer-head-and-neck-module
#14
Eva Hammerlid, Ali Adnan, Ewa Silander
BACKGROUND: The purpose of this study was to establish population-based norms for the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Head and Neck 35 (EORTC QLQ-HN35) to be used as references to facilitate the interpretation of results from health-related quality of life (HRQOL) studies of patients with head and neck cancer. METHODS: The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and QLQ-HN35 were sent to a random sample representing the Swedish general population...
July 14, 2017: Head & Neck
https://www.readbyqxmd.com/read/28707076/correlation-of-changes-in-patient-reported-quality-of-life-with-physician-rated-global-impression-of-change-in-patients-with-narcolepsy-participating-in-a-clinical-trial-of-sodium-oxybate-a-post-hoc-analysis
#15
Richard K Bogan, Jed Black, Todd Swick, Mortimer Mamelak, Ruzica Kovacevic-Ristanovic, Kathleen F Villa, Fannie Mori, Jacques Montplaisir
INTRODUCTION: Narcolepsy patients report lower health-related quality of life (HRQoL) than the general population, as measured by the Short Form-36 Health Survey (SF-36). This analysis evaluated whether changes in SF-36 correlated with physician-rated Clinical Global Impression of Change (CGI-C). METHODS: Data were from 209 of 228 narcolepsy patients participating in an 8-week clinical trial of sodium oxybate. Changes from baseline for SF-36 subscales (Physical Functioning, Role Physical, Bodily Pain, General Health, Vitality, Social Functioning, Role Emotional, and Mental Health) and the summary scores were evaluated for correlation with CGI-C overall and by treatment group...
July 13, 2017: Neurology and Therapy
https://www.readbyqxmd.com/read/28707048/psychometric-evaluation-of-an-item-bank-for-computerized-adaptive-testing-of-the-eortc-qlq-c30-cognitive-functioning-dimension-in-cancer-patients
#16
Linda Dirven, Mogens Groenvold, Martin J B Taphoorn, Thierry Conroy, Krzysztof A Tomaszewski, Teresa Young, Morten Aa Petersen
BACKGROUND: The European Organisation of Research and Treatment of Cancer (EORTC) Quality of Life Group is developing computerized adaptive testing (CAT) versions of all EORTC Quality of Life Questionnaire (QLQ-C30) scales with the aim to enhance measurement precision. Here we present the results on the field-testing and psychometric evaluation of the item bank for cognitive functioning (CF). METHODS: In previous phases (I-III), 44 candidate items were developed measuring CF in cancer patients...
July 13, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28705577/comparative-evaluation-of-bladder-specific-health-related-quality-of-life-hrqol-instruments-for-bladder-cancer
#17
T J Moncrief, P Balaji, B Lindgren, C J Weight, B R Konety
OBJECTIVE: To compare two bladder cancer specific health related quality of life instruments (HRQOL) in the same patient population. Previous HRQOL studies in cystectomy patients have yielded conflicting results. Using a cross sectional study design we examined the only two validated Bladder Cancer Specific (HRQOL) measures. METHODS: Of the 256 patients who had undergone (RC) from 2009-2014, 131 met both inclusion and exclusion criteria. The Functional Assessment Cancer Therapy-Vanderbilt Cystectomy Index (FACT-VCI) and Bladder Cancer Index (BCI) were mailed to these patients...
July 10, 2017: Urology
https://www.readbyqxmd.com/read/28705225/the-impact-of-social-engagement-on-health-related-quality-of-life-and-depressive-symptoms-in-old-age-evidence-from-a-multicenter-prospective-cohort-study-in-germany
#18
André Hajek, Christian Brettschneider, Tina Mallon, Annette Ernst, Silke Mamone, Birgitt Wiese, Siegfried Weyerer, Jochen Werle, Michael Pentzek, Angela Fuchs, Janine Stein, Tobias Luck, Horst Bickel, Dagmar Weeg, Michael Wagner, Kathrin Heser, Wolfgang Maier, Martin Scherer, Steffi G Riedel-Heller, Hans-Helmut König
BACKGROUND: Thus far, only a few longitudinal studies investigated the impact of social engagement on health-related quality of life (HRQoL) and depressive symptoms in old age. Therefore, we aimed to examine the impact of social engagement on HRQoL and depressive symptoms in late life. METHODS: Individuals aged 75 years and over at baseline were interviewed every 1.5 years in a multicenter prospective cohort study in Germany. While HRQoL was quantified by using the Visual Analogue Scale (EQ VAS) of the EQ-5D instrument, depressive symptoms was assessed by using the Geriatric Depression Scale (GDS)...
July 14, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28704584/patient-reported-outcomes-from-synergy-a-randomized-double-blind-multicenter-study-evaluating-combinations-of-mirabegron-and-solifenacin-compared-with-monotherapy-and-placebo-in-oab-patients
#19
Dudley Robinson, Con Kelleher, David Staskin, Elizabeth R Mueller, Christian Falconer, Jianye Wang, Arwin Ridder, Matthias Stoelzel, Asha Paireddy, Rob van Maanen, Zalmai Hakimi, Sender Herschorn
AIMS: To evaluate patient-reported outcomes (PROs) of combinations of solifenacin and mirabegron compared with solifenacin and mirabegron monotherapy and with placebo in patients with overactive bladder (OAB) from the SYNERGY trial. METHODS: Following a 4-week placebo run-in, period patients (≥18 years) with OAB were randomized 2:2:1:1:1:1 to receive solifenacin 5 mg + mirabegron 25 mg (combination 5 + 25 mg), solifenacin 5 mg + mirabegron 50 mg, (combination 5 + 50 mg), solifenacin 5 mg, mirabegron 25 mg, mirabegron 50 mg or placebo for 12 weeks, followed by a 2-week washout period...
July 13, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28704156/quality-of-life-in-patients-with-leg-ulcers-results-from-challenge-a-double-blind-randomised-controlled-trial
#20
S Meaume, A Dompmartin, C Lok, I Lazareth, M Sigal, F Truchetet, A Sauvadet, S Bohbot
OBJECTIVE: We recently showed the superiority of a matrix metalloproteinase (MMP) modulating dressing (foam impregnated with NOSF, nano-oligosaccharide factor) compared with a lipidocolloid matrix (TLC) control dressing in median wound area reduction (WAR). Here we report the results from the same study assessing the performance and safety of TLC-NOSF in the local management of venous leg ulcers (VLUs) or mixed leg ulcers and determining its impact on the patient's health-related quality of life (HRQoL)...
July 2, 2017: Journal of Wound Care
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