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https://www.readbyqxmd.com/read/28600616/utilization-of-body-contouring-procedures-following-weight-loss-surgery-a-study-of-37-806-patients
#1
Maria S Altieri, Jie Yang, Jihye Park, David Novikov, Lijuan Kang, Konstantinos Spaniolas, Andrew Bates, Mark Talamini, Aurora Pryor
BACKGROUND: Bariatric surgery has substantial health benefits; however, some patients desire body contouring (BC) procedures following rapid weight loss. There is a paucity of data regarding the true rate of BC following bariatric procedures. The purpose of our study is to examine the utilization of two common procedures, abdominoplasty, and panniculectomy, following bariatric surgery in New York State. METHODS: The SPARCS longitudinal administrative database was used to identify bariatric procedures by using ICD-9 and CPT codes between 2004 and 2010...
June 9, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28558193/influence-of-size-and-shape-on-the-anatomical-distribution-of-endotoxin-free-gold-nanoparticles
#2
Laura Talamini, Martina B Violatto, Qi Cai, Marco P Monopoli, Karsten Kantner, Željka Krpetić, André Perez-Potti, Jennifer Cookman, David Garry, Camila P Silveira, Luca Boselli, Beatriz Pelaz, Tommaso Serchi, Sébastien Cambier, Arno C Gutleb, Neus Feliu, Yan Yan, Mario Salmona, Wolfgang J Parak, Kenneth A Dawson, Paolo Bigini
The transport and the delivery of drugs through nanocarriers is a great challenge of pharmacology. Since the production of liposomes to reduce the toxicity of doxorubicin in patients, a plethora of nanomaterials have been produced and characterized. Although it is widely known that elementary properties of nanomaterials influence their in vivo kinetics, such interaction is often poorly investigated in many preclinical studies. The present study aims to evaluate the actual effect of size and shape on the biodistribution of a set of gold nanoparticles (GNPs) after intravenous administration in mice...
June 27, 2017: ACS Nano
https://www.readbyqxmd.com/read/28480391/anthelmintic-effects-of-dried-ground-banana-plant-leaves-musa-spp-fed-to-sheep-artificially-infected-with-haemonchus-contortus-and-trichostrongylus-colubriformis
#3
Lilian Gregory, Eidi Yoshihara, Leandro Kataoaka Fernandes Silva, Eduardo Carvalho Marques, Bruno Leonardo Mendonça Ribeiro, Enoch Brandão de Souza Meira, Rodolfo Santos Rossi, Alessandro Francisco Talamini do Amarante, Marjorie Yumi Hasegawa
BACKGROUND: Helminths is a endoparasites that cause the major losses for profitable sheep production in Brazil. The increased development of resistant strains of endoparasites have enforced the search for sustainable alternatives. The aim of this paper was to provide information about endoparasites control with banana leaves in infected sheep as alternative control strategies and see its viability. MATERIALS AND METHODS: In this study, we performed two trials to investigate the anthelmintic properties of banana leaves on endoparasites in sheep...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28299620/patient-acuity-and-operative-technique-associated-with-post-colectomy-mortality-across-new-york-state-an-analysis-of-160-792-patients-over-20%C3%A2-years
#4
Ryan Lamm, Steven N Mathews, Jie Yang, Jihye Park, Mark Talamini, Aurora D Pryor, Dana Telem
This study sought to characterize in-hospital post-colectomy mortality in New York State. One hundred sixty thousand seven hundred ninety-two patients who underwent colectomy from 1995 to 2014 were analyzed from the all-payer New York Statewide Planning and Research Cooperative System (SPARCS) database. Linear trends of in-hospital mortality rate over 20 years were calculated using log-linear regression models. Chi-square tests were used to compare categorical variables between patients. Multivariable regression models were further used to calculate risk of in-hospital mortality associated with specific demographics, co-morbidities, and perioperative complications...
May 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28282007/hospital-charge-and-health-care-quality-in-bariatric-surgery
#5
Dana A Telem, Jie Yang, Maria Altieri, Mark Talamini, Qiao Zhang, Aurora D Pryor
To determine if hospital charges correlate with patient outcomes after bariatric surgery. A retrospective review of 46,180 patients who underwent bariatric surgery from 2004-2010 was performed. Patients were identified using the New York Statewide Planning and Research Cooperative System database. Hospitals were categorized on estimates from a multiple linear regression model for charge: low (<$25,027.00), medium ($25,027.00-$35,449.00), and high (≥$35,449.01). Patient outcomes were compared among the charge classification...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28242087/surgeons-perceptions-on-industry-relations-a-survey-of-822-surgeons
#6
Maria S Altieri, Jie Yang, Lily Wang, Donglei Yin, Mark Talamini, Aurora D Pryor
BACKGROUND: The relationships between industry and medical professionals are controversial. The purpose of our study was to evaluate surgeons' current opinions regarding the industry-surgery partnership, in addition to self-reported industry ties. METHODS: After institutional review board approval, a survey was sent via RedCap to 3,782 surgeons across the United States. Univariate and multivariable regression analyses were performed to evaluate the responses. RESULTS: The response rate was 23%...
February 24, 2017: Surgery
https://www.readbyqxmd.com/read/28228204/hospital-charge-and-health-care-quality-in-bariatric-surgery
#7
Dana A Telem, Jie Yang, Maria Altieri, Mark Talamini, Qiao Zhang, Aurora D Pryor
To determine if hospital charges correlate with patient outcomes after bariatric surgery. A retrospective review of 46,180 patients who underwent bariatric surgery from 2004-2010 was performed. Patients were identified using the New York Statewide Planning and Research Cooperative System database. Hospitals were categorized on estimates from a multiple linear regression model for charge: low (<$25,027.00), medium ($25,027.00-$35,449.00), and high (≥$35,449.01). Patient outcomes were compared among the charge classification...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28174235/an-integrated-approach-identifies-mediators-of-local-recurrence-in-head-and-neck-squamous-carcinoma
#8
Francesca Citron, Joshua Armenia, Giovanni Franchin, Jerry Polesel, Renato Talamini, Sara D'Andrea, Sandro Sulfaro, Carlo M Croce, William Klement, David Otasek, Chiara Pastrello, Tomas Tokar, Igor Jurisica, Deborah French, Riccardo Bomben, Emanuela Vaccher, Diego Serraino, Barbara Belletti, Andrea Vecchione, Luigi Barzan, Gustavo Baldassarre
Purpose: Head and neck squamous cell carcinomas (HNSCCs) cause more than 300,000 deaths worldwide each year. Locoregional and distant recurrences represent worse prognostic events and accepted surrogate markers of patients' overall survival. No valid biomarker and salvage therapy exist to identify and treat patients at high-risk of recurrence. We aimed to verify if selected miRNAs could be used as biomarkers of recurrence in HNSCC.Experimental Design: A NanoString array was used to identify miRNAs associated with locoregional recurrence in 44 patients with HNSCC...
February 7, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27936802/biocompatible-polymer-nanoformulation-to-improve-the-release-and-safety-of-a-drug-mimic-molecule-detectable-via-icp-ms
#9
Raffaele Ferrari, Laura Talamini, Martina Bruna Violatto, Paola Giangregorio, Mattia Sponchioni, Massimo Morbidelli, Mario Salmona, Paolo Bigini, Davide Moscatelli
Fluorescent poly(ε-caprolactone)-based nanoparticles (NPs) have been synthesized and successfully loaded with a titanium organometallic compound as a mimic of a water-insoluble drug. The nature of this nanovector enabled us to combine the quantification of the metal in tissues after systemic administration in healthy immunocompetent mice by inductively coupled plasma mass spectroscopy (ICP-MS) followed by the visualization of NPs in organ sections by confocal microscopy. This innovative method of nanodrug screening has enabled us to elucidate the crucial parameters of their kinetics...
January 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/27924393/autologous-augmentation-of-hiatal-hernia-repair-with-filtered-platelet-concentrate-improves-tissue-remodeling-in-a-swine-model
#10
Maria S Altieri, Gabriel Pagnotti, Angelique Corthals, Kenneth Shroyer, Aurora D Pryor, Mark Talamini, Dana A Telem
INTRODUCTION: Autologus augmentation of wound remodeling with platelet concentrate is a burgeoning field with promising results. We hypothesized that the addition of filtered platelet concentrate (fPC) to an acellular biologic graft would improve crural healing and tissue integrity in hiatal hernia repair. METHODS: Sixteen healthy Yorkshire female pigs were divided into three groups: hiatus repair (HR) (n = 7), HR with biologic graft (HRM; n = 8, and HR with biologic graft and fPC (fPC; n = 9)...
December 6, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27815743/presence-of-a-fellowship-improves-perioperative-outcomes-following-hepatopancreatobiliary-procedures
#11
Maria S Altieri, Jie Yang, Donglei Yin, Catherine Frenkel, Mark Talamini, Dana A Telem, Aurora Pryor
INTRODUCTION: There is an increase in subspecialization and in the number of surgeons seeking fellowship training in the USA. Little is known regarding the effect of hepatopancreatobiliary (HPB) fellowship programs' status of an institution on perioperative outcomes. This study aims to examine the effect of such status on perioperative outcomes across all institutions following complex surgeries involving HPB procedures in the State of New York (NYS). METHODS: The Statewide Planning and Research Cooperative System administrative database was used to identify several complex surgeries involving the pancreas, liver, and gallbladder by using ICD-9 codes for inpatient procedures between 2012 and 2014...
July 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/27770111/correction-sunitinib-prevents-cachexia-and-prolongs-survival-of-mice-bearing-renal-cancer-by-restraining-stat3-and-murf-1-activation-in-muscle
#12
Francesca Pretto, Carmen Ghilardi, Michele Moschetta, Andrea Bassi, Alessandra Rovida, Valentina Scarlato, Laura Talamini, Fabio Fiordaliso, Cinzia Bisighini, Giovanna Damia, Maria Rosa Bani, Rosanna Piccirillo, Raffaella Giavazzi
No abstract text is available yet for this article.
June 21, 2016: Oncotarget
https://www.readbyqxmd.com/read/27613732/factors-associated-with-repeated-health-resource-utilization-in-patients-with-diverticulitis
#13
Steven N Mathews, Ryan Lamm, Jie Yang, Lijuan Kang, Dana Telem, Aurora D Pryor, Mark Talamini, Jill Genua
Conservative management trends in diverticulitis may lead to increased hospitalizations secondary to repeated attacks. The study aimed to characterize trends in management and risk-assess patients with diverticulitis that required multiple admissions to identify high utilizers. A total of 265,724 patients with diverticulitis were identified from 1995 to 2014 from the New York SPARCS database. Patients with ≥2 hospital admissions were stratified across demographics, comorbidities, insurance status, and surgical intervention...
January 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27604366/nineteen-year-trends-in-incidence-and-indications-for-laparoscopic-cholecystectomy-the-ny-state-experience
#14
Vamsi V Alli, Jie Yang, Jianjin Xu, Andrew T Bates, Aurora D Pryor, Mark A Talamini, Dana A Telem
BACKGROUND: Since the introduction of laparoscopic cholecystectomy (LC), there has been continued evolution in technique, instrumentation and postoperative management. With increased experience, LC has migrated to the outpatient setting. We asked whether increased availability and experience has impacted incidence of and indications for LC. METHODS: The New York (NY) State Planning and Research Cooperative System longitudinal administrative database was utilized to identify patients who underwent cholecystectomy between 1995 and 2013...
April 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/27456012/20-year-trends-in-the-management-of-diverticulitis-across-new-york-state-an-analysis-of-265-724-patients
#15
Ryan Lamm, Steven N Mathews, Jie Yang, Lijuan Kang, Dana Telem, Aurora D Pryor, Mark Talamini, Jill Genua
INTRODUCTION: Management of acute diverticulitis (AD) has considerably changed over time. This study evaluates practice patterns for diverticulitis across demographic populations in New York State. METHODS: Two hundred sixty-five thousand seven hundred twenty-four patients with acute diverticulitis were analyzed from 1995 to 2014 from the New York-Statewide Planning and Research Cooperative System database. The likelihood of having surgery over time was compared across patient demographic subgroups using logistic regression models to calculate estimated odds ratio with their 95 % confidence intervals...
January 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27451226/determination-of-pesticides-in-coconut-cocos-nucifera-linn-water-and-pulp-using-modified-quechers-and-lc-ms-ms
#16
Jordana Alves Ferreira, Joana Maria Santos Ferreira, Viviane Talamini, Janice de Fátima Facco, Tiele Medianeira Rizzetti, Osmar Damian Prestes, Martha Bohrer Adaime, Renato Zanella, Carla Beatriz Grespan Bottoli
The use of pesticides is directly linked to improvements in productivity and to the preservation of coconut palms. However pesticide analysis is necessary to determine whether pesticide residues in the food products containing coconut are within the maximum residue limits (MRLs), ensuring the quality of these products. This work aimed to develop a method for multiresidue determination of ten pesticides in coconut water and pulp using QuEChERS and LC-MS/MS. The method was effective in terms of selectivity, linearity, matrix effect, accuracy and precision, providing LOD of 3μgkg(-1), LOQ of 10μgkg(-1) and recoveries between 70 and 120% with RSD lower than 20%...
December 15, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27441900/protection-of-brain-injury-by-amniotic-mesenchymal-stromal-cell-secreted-metabolites
#17
Francesca Pischiutta, Laura Brunelli, Pietro Romele, Antonietta Silini, Eliana Sammali, Lara Paracchini, Sergio Marchini, Laura Talamini, Paolo Bigini, Giorgio B Boncoraglio, Roberta Pastorelli, Maria-Grazia De Simoni, Ornella Parolini, Elisa R Zanier
OBJECTIVES: To define the features of human amniotic mesenchymal stromal cell secretome and its protective properties in experimental models of acute brain injury. DESIGN: Prospective experimental study. SETTING: Laboratory research. SUBJECTS: C57Bl/6 mice. INTERVENTIONS: Mice subjected to sham or traumatic brain injury by controlled cortical impact received human amniotic mesenchymal stromal cells or phosphate-buffered saline infused intracerebroventricularly or intravenously 24 hours after injury...
November 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27369285/long-term-incidence-of-contralateral-primary-hernia-repair-following-unilateral-inguinal-hernia-repair-in-a-cohort-of-32-834-patients
#18
Richard Zheng, Maria S Altieri, Jie Yang, Hao Chen, Aurora D Pryor, Andrew Bates, Mark A Talamini, Dana A Telem
BACKGROUND: Asymptomatic contralateral inguinal hernias are often present during initial inguinal hernia repair. Data on long-term results and progression to symptomaticity are sparse. The purpose of this study was to assess long-term rates and risk factors for contralateral inguinal hernia repair following unilateral inguinal hernia repair. METHODS: Using New York Statewide Planning and Research Collaborative administrative data, 32,384 adults who underwent initial inguinal hernia repair during 2002-2003 in New York State and achieved 10-year follow-up were identified...
February 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/27212031/activation-of-the-sdf1-cxcr4-pathway-retards-muscle-atrophy-during-cancer-cachexia
#19
G B Martinelli, D Olivari, A D Re Cecconi, L Talamini, L Ottoboni, S H Lecker, C Stretch, V E Baracos, O F Bathe, A Resovi, R Giavazzi, L Cervo, R Piccirillo
Cancer cachexia is a life-threatening syndrome that affects most patients with advanced cancers and causes severe body weight loss, with rapid depletion of skeletal muscle. No treatment is available. We analyzed microarray data sets to identify a subset of genes whose expression is specifically altered in cachectic muscles of Yoshida hepatoma-bearing rodents but not in those with diabetes, disuse, uremia or fasting. Ingenuity Pathways Analysis indicated that three genes belonging to the C-X-C motif chemokine receptor 4 (CXCR4) pathway were downregulated only in muscles atrophying because of cancer: stromal cell-derived factor 1 (SDF1), adenylate cyclase 7 (ADCY7), and p21 protein-activated kinase 1 (PAK1)...
December 1, 2016: Oncogene
https://www.readbyqxmd.com/read/27129561/effect-of-minimally-invasive-surgery-fellowship-on-residents-operative-experience
#20
Maria S Altieri, Catherine Frenkel, Richard Scriven, Deborah Thornton, Caitlin Halbert, Mark Talamini, Dana A Telem, Aurora D Pryor
INTRODUCTION: There is an increased need for surgical trainees to acquire advanced laparoscopic skills as laparoscopy becomes the standard of care in many areas of general surgery. Since the introduction of minimally invasive surgery (MIS) fellowships, there has been a continuing debate as to whether these fellowships adversely affect general surgery resident exposure to laparoscopic cases. The aim of our study was to examine whether the introduction of an MIS fellowship negatively impacts general surgery residents' experience at a single academic center...
January 2017: Surgical Endoscopy
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