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https://www.readbyqxmd.com/read/28503333/peritoneal-keratin-granulomatosis-associated-with-endometrioid-adenocarcinoma-of-the-uterine-corpus-in-a-woman-with-polycystic-ovaries-a-potential-pitfall-a-case-report-and-review-of-the-literature
#1
Helen J Trihia, Maria Papazian, Natasa Novkovic, John Provatas, Sotiria Tsangouri, Dimitrios C Papatheodorou
Peritoneal keratin granulomatosis is a rare condition included under granulomatous lesions of the peritoneum. It can be secondary to neoplasms of the female genital tract and can mimic carcinomatosis intraoperatively. A case of a 40-year-old woman with a history of polycystic ovaries and a chief complaint of vaginal bleeding is presented. She was diagnosed with endometrioid adenocarcinoma with squamous differentiation in endometrial curettings. Intraoperatively, many peritoneal nodules were found, interpreted as peritoneal carcinomatosis...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28494525/ultrasonography-of-pediatric-urogenital-emergencies-review-of-classic-and-new-techniques
#2
Masahiro Kitami
Urogenital emergencies are fairly common in the pediatric population, and a timely and correct diagnosis is necessary to avoid possible future infertility. In this field, ultrasonography is essential, as it has the advantages of being radiation-free and readily accessible. In particular, a high-frequency transducer allows precise evaluation of the morphology and vascularity of the scrotum, which is on the surface of the body. Beyond conventional techniques, new advanced imaging techniques have been developed, including elastography and contrast-enhanced ultrasonography...
March 30, 2017: Ultrasonography
https://www.readbyqxmd.com/read/28493071/nontraumatic-large-bowel-perforation-spectrum-of-etiologies-and-ct-findings
#3
REVIEW
Kunal Kothari, Barak Friedman, Gregory M Grimaldi, John J Hines
Large bowel perforation is an abdominal emergency that results from a wide range of etiologies. Computed tomography is the most reliable modality in detecting the site of large bowel perforation. The diagnosis is made by identifying direct CT findings such as extraluminal gas or contrast and discontinuity along the bowel wall. Indirect CT findings can help support the diagnosis, and include bowel wall thickening, pericolic fat stranding, abnormal bowel wall enhancement, abscess, and a feculent collection adjacent to the bowel...
May 10, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28492924/handheld-reflectance-confocal-microscopy-for-the-detection-of-recurrent-extramammary-paget-disease
#4
Oriol Yélamos, Brian P Hibler, Miguel Cordova, Travis J Hollmann, Kivanc Kose, Michael A Marchetti, Patricia L Myskowski, Melissa P Pulitzer, Milind Rajadhyaksha, Anthony M Rossi, Manu Jain
Importance: Extramammary Paget disease (EMPD) is commonly refractory to surgical and nonsurgical therapies. Identifying recurrent or persistent EMPD is challenging because the disease is multifocal, and multiple blind scouting biopsies are usually performed in this setting. Handheld reflectance confocal microscopy (HRCM) has been used to diagnose and map primary EMPD and therefore may be used to identify EMPD recurrences. Objective: To evaluate HRCM's diagnostic accuracy in the setting of recurrent or persistent EMPD as well as its potential diagnostic pitfalls...
May 10, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28489715/assessment-of-malpractice-claims-associated-with-acute-compartment-syndrome
#5
John Mason DePasse, Rachel Sargent, Amanda J Fantry, Steven L Bokshan, Mark A Palumbo, Alan H Daniels
BACKGROUND: Because acute compartment syndrome is one of the few limb-threatening and life-threatening orthopaedic conditions and is difficult to diagnose, it is a frequent source of litigation. Understanding the factors that lead to plaintiff verdicts and higher indemnity payments may improve patient care by identifying common pitfalls. METHODS: The VerdictSearch legal claims database was queried for the term "compartment syndrome." After 46 cases were excluded for missing information or irrelevancy, 139 cases were reviewed...
June 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28473139/tricuspid-valve-dysfunction-following-pacemaker-or-cardioverter-defibrillator-implantation
#6
REVIEW
James D Chang, Warren J Manning, Elisa Ebrille, Peter J Zimetbaum
The potential for cardiac implantable electronic device leads to interfere with tricuspid valve (TV) function has gained increasing recognition as having hemodynamic and clinical consequences associated with incremental morbidity and death. The diagnosis and treatment of lead-related (as distinct from functional) tricuspid regurgitation pose unique challenges. Because of pitfalls in routine diagnostic imaging, a high level of clinical suspicion must be maintained to avoid overlooking the possibility that worsening heart failure is a consequence of mechanical interference with TV leaflet mobility or coaptation and is amenable to lead extraction or valve repair or replacement...
May 9, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28467215/a-systematic-analysis-of-discordant-diagnoses-in-digital-pathology-compared-with-light-microscopy
#7
Bethany J Williams, Philip DaCosta, Edward Goacher, Darren Treanor
CONTEXT: - Relatively little is known about the significance and potential impact of glass-digital discordances, and this is likely to be of importance when considering digital pathology adoption. OBJECTIVE: - To apply evidence-based medicine to collect and analyze reported instances of glass-digital discordance from the whole slide imaging validation literature. DESIGN: - We used our prior systematic review protocol to identify studies assessing the concordance of light microscopy and whole slide imaging between 1999 and 2015...
May 3, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28461968/the-tactics-and-technique-of-musculoskeletal-biopsy
#8
REVIEW
G Ulrich Exner, Michael O Kurrer, Nadja Mamisch-Saupe, Stephen R Cannon
The treatment of musculoskeletal neoplasms and infection is usually based on an initial diagnostic biopsy.Prior to biopsy, a hypothesis should be formed about the most likely diagnosis and a differential diagnosis. These deliberations should consider whether the lesion is a primary benign or malignant tumour, a metastasis, a haematological problem or an infection.A tactical plan should be developed which evaluates the necessity, the risk, the approach and finally defines the technique of biopsy most likely to achieve a representative result in the clinical case...
February 2017: EFORT Open Rev
https://www.readbyqxmd.com/read/28456990/prenatal-diagnosis-of-lysosomal-storage-disorders-using-chorionic-villi
#9
Jyotsna Verma, Sunita Bijarnia-Mahay, Ishwar C Verma
Prenatal enzymatic diagnosis for an array of lysosomal storage disorders (LSDs) can be performed accurately, provided that a confirmed diagnosis by biochemical/molecular study in the index case is available and a strict defined protocol, specific to each individual disorder is followed. The present chapter describes the protocols for reliable and accurate prenatal enzymatic diagnoses by fluorometric and spectrophotometric methods of lysosomal storage disorders: Gaucher, Fabry, Pompe, Niemann Pick A/B, Tay Sach, Sandhoff, GM1, Mucoplysaccharidoses, Wolman, Krabbe, Metachromatic leukodystrophy, and Batten diseases using uncultured chorionic villi samples...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28447662/expert-consensus-document-echocardiography-and-lung-ultrasonography-for-the-assessment-and-management-of-acute-heart-failure
#10
REVIEW
Susanna Price, Elke Platz, Louise Cullen, Guido Tavazzi, Michael Christ, Martin R Cowie, Alan S Maisel, Josep Masip, Oscar Miro, John J McMurray, W Frank Peacock, F Javier Martin-Sanchez, Salvatore Di Somma, Hector Bueno, Uwe Zeymer, Christian Mueller
Echocardiography is increasingly recommended for the diagnosis and assessment of patients with severe cardiac disease, including acute heart failure. Although previously considered to be within the realm of cardiologists, the development of ultrasonography technology has led to the adoption of echocardiography by acute care clinicians across a range of specialties. Data from echocardiography and lung ultrasonography can be used to improve diagnostic accuracy, guide and monitor the response to interventions, and communicate important prognostic information in patients with acute heart failure...
April 27, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28442807/epidemiology-and-clinico-investigative-study-of-organisms-causing-vaginal-discharge
#11
Swetha Venugopal, Kannan Gopalan, Asha Devi, A Kavitha
BACKGROUND: Abnormal vaginal discharge is a common clinical problem in reproductive age group. It is the second most common problem after abnormal uterine bleeding. It is a neglected health problem, most commonly caused due to vulvovaginal candidiasis, trichomoniasis, and bacterial vaginosis (BV). OBJECTIVES: The present study was conducted to determine the prevalence of common organisms causing vaginal discharge and also to know the variety of clinical presentation...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28439689/divergent-schwannoma-like-phenotype-in-a-pleomorphic-adenoma
#12
Srinivasa R Chandra, Farah Karim, Yeshwant B Rawal
The schwannoma-like pleomorphic adenoma is a rare histopathological variant of the pleomorphic adenoma. Five previous reports with seven cases exist in English language literature. These tumors present in the parotid gland most commonly. Intraparotid schwannomas of the facial nerve and schwannomas with glandular differentiation have also been reported. A 60-year-old male presented with an asymptomatic swelling over the left angle of the mandible. The swelling had been present for about 12 years with a recent increase in size...
April 24, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28432659/current-role-of-blood-and-urine-biomarkers-in-the-clinical-care-of-adults-with-congenital-heart-disease
#13
REVIEW
Saurabh Rajpal, Laith Alshawabkeh, Alexander R Opotowsky
PURPOSE OF REVIEW: There is an increasing number of adult patients with congenital heart disease (CHD). While several biomarkers have been validated and integrated into general cardiology clinical practice, these tests are often applied to adults with CHD in the absence of disease-specific validation. Although these patients are often grouped into a single population, there is heterogeneous pathophysiology, variable disease chronicity, extensive multisystem involvement, and a low event rate relative to acquired heart disease...
June 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28429200/achalasia-it-is-not-all-black-and-white
#14
REVIEW
Santosh Sanagapalli, Rami Sweis
PURPOSE OF REVIEW: This review aims to shed light on subtleties of achalasia diagnosis, including potential pitfalls that may lead to errors. Optimal methods for assessment of disease severity and the relationship between achalasia and other motility disorders will also be reviewed with an emphasis on recent findings from the literature. RECENT FINDINGS: Adjunctive testing with viscous substances or larger water volumes should be used routinely as it improves the accuracy of achalasia diagnosis...
June 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28421710/synovial-sarcoma-metastatic-to-the-parotid-gland-a-possible-pitfall-in-salivary-gland-fine-needle-aspiration-cytology-report-of-a-case-with-immunocytochemical-and-fluorescence-in-situ-hybridization-findings
#15
Franco Fulciniti, Jessica Barizzi, Vittoria Martin, Vittorio Tarallo, Stefano Ermanni
We report one case of metastatic synovial sarcoma (SS) to the parotid gland in a 93-year-old male. The patient had undergone upper left pulmonary lobectomy with mediastinal lymphadenectomy for SS of the lung 5 years before. The cytopathologic presentation and the immunocytochemical findings on the FNA sample were suggestive of a spindle cell myoepithelioma, while a SYT rearrangement was identified by a FISH performed on a cytological smear of the lesion. The diagnosis was further confirmed also by positive immunocytochemical expression of TLE1 on a section from the obtained cell block...
April 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28413206/differential-diagnostic-significance-of-hbme-1-ck19-and-s100-in-various-thyroid-lesions
#16
S Palo, D S Biligi
OBJECTIVE: Due several overlapping histomorphological features and pitfalls in thyroid pathology, there is need to establish a panel of immunomarkers that would aid in proper diagnosis. This study was carried out to investigate the ability of HBME-1, CK19, and S100 in differentiating between hyperplastic, benign and malignant thyroid lesions. MATERIALS AND METHODS: Immunohistochemical analysis of 60 thyroidectomy specimens (10 hyperplastic nodules, 14 follicular adenomas and 36 malignant thyroid neoplasms) was carried out...
April 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28411397/chondrosarcoma-like-metastasis-from-a-poorly-differentiated-uterine-cervical-squamous-cell-carcinoma-a-unique-morphology-and-diagnostic-pitfall-in-cytology
#17
Shohei Ikoma, Marlo Nicolas, Jaishree Jagirdar, Maria Luisa Policarpio-Nicolas
Rare cases of metastatic squamous cell carcinoma with chondroid differentiation from esophageal primary have been reported but none from the uterine cervix. Given the rarity of this phenomenon and potential diagnostic pitfall, we present this unusual case. The patient is a 25-year-old woman who presented with shortness of breath. Computerized tomography (CT) showed several lung and pleural-based nodules. CT-guided core biopsy with touch preparations were performed on the pleural-based nodule. The touch preparations showed large, spindle-to-oval shaped cells with pleomorphic nuclei embedded in metachromatic chondroid stroma...
April 14, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28399846/palliative-sedation-challenging-the-professional-competency-of-health-care-providers-and-staff-a-qualitative-focus-group-and-personal-written-narrative-study
#18
Danièle Leboul, Régis Aubry, Jean-Michel Peter, Victor Royer, Jean-François Richard, Frédéric Guirimand
BACKGROUND: Despite recent advances in palliative medicine, sedating a terminally ill patient is regarded as an indispensable treatment to manage unbearable suffering. With the prospect of widespread use of palliative sedation, the feelings and representations of health care providers and staff (carers) regarding sedation must be carefully explored if we are to gain a better understanding of its impact and potential pitfalls. The objective of the study was to provide a comprehensive description of the opinions of carers about the use of sedation practices in palliative care units (PCU), which have become a focus of public attention following changes in legislation...
April 11, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28398699/pneumocytoma-sclerosing-hemangioma-a-potential-pitfall
#19
Erika Hissong, Rema Rao
Pneumocytoma is an uncommon benign tumor of the lung, derived from primitive respiratory epithelium, with a predilection for middle-aged females. A single, well-circumscribed mass is commonly identified on imaging, necessitating pathologic evaluation for further assessment. Fine-needle aspiration cytology is a minimally invasive and cost-effective method that can be utilized in the diagnosis of these lesions. Yet, distinction of pneumocytoma from other entities such as well-differentiated adenocarcinoma or carcinoid tumor can be quite challenging...
April 11, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28393379/surveillance-neck-sonography-after-thyroidectomy-for-papillary-thyroid-carcinoma-pitfalls-in-the-diagnosis-of-locally-recurrent-and-metastatic-disease
#20
Wynne Yuru Chua, Jill E Langer, Lisa P Jones
A sonographic examination of the neck performed 6 to 12 months after thyroid surgery in patients with differentiated thyroid cancer is strongly recommended by the American Thyroid Association and considered mandatory by the European Thyroid Association for locoregional surveillance. The aim of this article is to review the normal anatomic changes expected after thyroid surgery and the pathologic mimics of thyroid carcinoma recurrence in post-thyroidectomy patients as they appear on neck sonography. We hope to offer some pearls to increase diagnostic confidence in this setting...
April 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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