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Ronald Epstein

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https://www.readbyqxmd.com/read/29608090/review-of-attending-medicine-mindfulness-and-humanity
#1
Valerie Ross
Reviews the book, Attending: Medicine, Mindfulness, and Humanity by Ronald Epstein (2017). In this extraordinary book, Epstein places mindfulness at the center of the healing encounter and argues that doing so is an ethical imperative. In this time of widespread physician burnout and rapid systems change, this book is necessary reading for educators, activists, and leaders who want to promote quality, compassionate care, and physician well-being. Most important, the reviewer recommends his book to all health care providers who want to reconnect with their own heart and soul...
March 2018: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://www.readbyqxmd.com/read/29581034/preference-for-palliative-care-in-cancer-patients-are-men-and-women-alike
#2
Fahad Saeed, Michael Hoerger, Sally A Norton, Elizabeth Guancial, Ronald M Epstein, Paul R Duberstein
CONTEXT: Men and those with low educational attainment are less likely to receive palliative care. Understanding these disparities is a high priority issue. OBJECTIVE: In this study of advanced cancer patients, we hypothesized that men and those with lower levels of educational attainment would have less favorable attitudes towards palliative care. METHODS: We performed a cross-sectional analysis of data collected from 383 patients at study entry in the Values and Options in Cancer Care (VOICE) clinical trial...
March 23, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29575388/the-ecology-of-patient-and-caregiver-participation-in-consultations-involving-advanced-cancer
#3
Jennifer Freytag, Richard L Street, Guibo Xing, Paul R Duberstein, Kevin Fiscella, Daniel J Tacredi, Joshua J Fenton, Richard L Kravitz, Ronald M Epstein
OBJECTIVE: To identify predictors of participation of patients with advanced cancer in clinical encounters with oncologists and to assess the impact of patient and caregiver participation on perceptions of physician support. METHODS: This is a secondary data analysis from the Values and Options in Cancer Care (VOICE) study, a cluster randomized clinical trial of a patient-centered communication intervention. Patients and caregivers completed pre- and post-visit health and communication measures...
March 25, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29523669/community-oncologists-decision-making-for-treatment-of-older-patients-with-cancer
#4
Supriya G Mohile, Allison Magnuson, Chintan Pandya, Carla Velarde, Paul Duberstein, Arti Hurria, Kah Poh Loh, Megan Wells, Sandy Plumb, Nikesha Gilmore, Marie Flannery, Marsha Wittink, Ronald Epstein, Charles E Heckler, Michelle Janelsins, Karen Mustian, Judith O Hopkins, Jane Liu, Srihari Peri, William Dale
Background: This study's objectives were to describe community oncologists' beliefs about and confidence with geriatric care and to determine whether geriatric-relevant information influences cancer treatment decisions. Methods: Community oncologists were recruited to participate in 2 multisite geriatric oncology trials. Participants shared their beliefs about and confidence in caring for older adults. They were also asked to make a first-line chemotherapy recommendation (combination vs single-agent vs no chemotherapy) for a hypothetical vignette of an older patient with advanced pancreatic cancer...
March 2018: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29432452/a-conserved-eph-family-receptor-binding-motif-on-the-gh-gl-complex-of-kaposi-s-sarcoma-associated-herpesvirus-and-rhesus-monkey-rhadinovirus
#5
Anna K Großkopf, Armin Ensser, Frank Neipel, Doris Jungnickl, Sarah Schlagowski, Ronald C Desrosiers, Alexander S Hahn
Kaposi's sarcoma-associated herpesvirus (KSHV) is a human oncogenic virus associated with Kaposi's sarcoma and two B-cell malignancies. The rhesus monkey rhadinovirus (RRV) is a virus of nonhuman primates that is closely related to KSHV. Eph family receptor tyrosine kinases (Ephs) are cellular receptors for the gH/gL glycoprotein complexes of both KSHV and RRV. Through sequence analysis and mutational screens, we identified conserved residues in the N-terminal domain of KSHV and RRV glycoprotein H that are critical for Eph-binding in vitro...
February 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29426719/safety-and-preliminary-efficacy-of-vorinostat-with-r-epoch-in-high-risk-hiv-associated-non-hodgkin-s-lymphoma-amc-075
#6
Juan C Ramos, Joseph A Sparano, Michelle A Rudek, Page C Moore, Ethel Cesarman, Erin G Reid, David Henry, Lee Ratner, David Aboulafia, Jeanette Y Lee, Richard F Ambinder, Ronald Mitsuyasu, Ariela Noy
INTRODUCTION: Vorinostat (VOR), a histone deacetylase inhibitor, enhances the anti-tumor effects of rituximab (R) and cytotoxic chemotherapy, induces viral lytic expression and cell killing in Epstein-Barr virus-positive (EBV+ ) or human herpesvirus-8-positive (HHV-8+ ) tumors, and reactivates latent human immunodeficiency virus (HIV) for possible eradication by combination antiretroviral therapy (cART). PATIENTS AND METHODS: We performed a phase I trial of VOR given with R-based infusional EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin hydrochloride) (n = 12) and cART in aggressive HIV-associated B-cell non-Hodgkin lymphoma (NHL) in order to identify safe dosing and schedule...
March 2018: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/29148892/impact-of-prognostic-discussions-on-the-patient-physician-relationship-prospective-cohort-study
#7
Joshua J Fenton, Paul R Duberstein, Richard L Kravitz, Guibo Xing, Daniel J Tancredi, Kevin Fiscella, Supriya Mohile, Ronald M Epstein
Purpose Some research has suggested that discussion of prognosis can disrupt the patient-physician relationship. This study assessed whether physician discussion of prognosis is associated with detrimental changes in measures of the strength of the patient-physician relationship. Methods This was a longitudinal cohort study of 265 adult patients with advanced cancer who visited 38 oncologists within community- and hospital-based cancer clinics in Western New York and Northern California. Prognostic discussion was assessed by coding transcribed audio-recorded visits using the Prognostic and Treatment Choices (PTCC) scale and by patient survey at 3 months after the clinic visit...
November 17, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29109138/author-response-education-research-positive-effect-of-scheduled-faculty-modeling-on-clerkship-student-bedside-skills-exposure-and-learning
#8
Robert Thompson Stone, Trenton Tollefson, Ronald Epstein, Ralph F Jozefowicz, Jonathan W Mink
No abstract text is available yet for this article.
November 7, 2017: Neurology
https://www.readbyqxmd.com/read/28952370/preventive-dental-care-at-6-month-intervals-is-associated-with-reduced-caries-risk
#9
Valerie J Flaherman, Jacqueline Epstein, Louis Amendola, Ronald Inge, John D Featherstone, Megumi Okumura
No abstract text is available yet for this article.
February 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/28892432/patient-clinician-communication-american-society-of-clinical-oncology-consensus-guideline
#10
REVIEW
Timothy Gilligan, Nessa Coyle, Richard M Frankel, Donna L Berry, Kari Bohlke, Ronald M Epstein, Esme Finlay, Vicki A Jackson, Christopher S Lathan, Charles L Loprinzi, Lynne H Nguyen, Carole Seigel, Walter F Baile
Purpose To provide guidance to oncology clinicians on how to use effective communication to optimize the patient-clinician relationship, patient and clinician well-being, and family well-being. Methods ASCO convened a multidisciplinary panel of medical oncology, psychiatry, nursing, hospice and palliative medicine, communication skills, health disparities, and advocacy experts to produce recommendations. Guideline development involved a systematic review of the literature and a formal consensus process. The systematic review focused on guidelines, systematic reviews and meta-analyses, and randomized controlled trials published from 2006 through October 1, 2016...
November 1, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28841847/the-social-and-behavioral-influences-sbi-study-study-design-and-rationale-for-studying-the-effects-of-race-and-activation-on-cancer-pain-management
#11
Cezanne M Elias, Cleveland G Shields, Jennifer J Griggs, Kevin Fiscella, Sharon L Christ, Joseph Colbert, Stephen G Henry, Beth G Hoh, Haslyn E R Hunte, Mary Marshall, Supriya Gupta Mohile, Sandy Plumb, Mohamedtaki A Tejani, Alison Venuti, Ronald M Epstein
BACKGROUND: Racial disparities exist in the care provided to advanced cancer patients. This article describes an investigation designed to advance the science of healthcare disparities by isolating the effects of patient race and patient activation on physician behavior using novel standardized patient (SP) methodology. METHODS/DESIGN: The Social and Behavioral Influences (SBI) Study is a National Cancer Institute sponsored trial conducted in Western New York State, Northern/Central Indiana, and lower Michigan...
August 25, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28806452/sharing-experiences-of-illness-and-care
#12
Louise Locock, Richard Lehman, Ronald M Epstein
No abstract text is available yet for this article.
September 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28659511/ronald-epstein-md-bringing-mindfulness-into-the-examination-room
#13
Ronald Epstein
Advances in Mind-Body Medicine (Advances): You have come out with a book recently, titled Attending: Medicine, Mindfulness, and Humanity. What was the motive for writing this book? Dr Epstein: I knew that it was time to expand beyond writing for medical audiences and peer-reviewed journals when 2 realizations struck me. One is that important change in medicine often comes from the outside in as opposed to from the inside out. The degree to which the public is educated and energized about an issue can produce a change in medicine...
April 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28607143/education-research-positive-effect-of-scheduled-faculty-modeling-on-clerkship-student-bedside-skills-exposure-and-learning
#14
Robert Thompson Stone, Trenton Tollefson, Ronald Epstein, Ralph F Jozefowicz, Jonathan W Mink
OBJECTIVE: To evaluate the effect of scheduled bedside skills modeling for third-year medical students on their neurology clerkship. METHODS: During the 2012-2014 academic years, 56 third-year medical students participated in a curricular pilot program involving a scheduled bedside skills modeling experience during the first week of their neurology clerkship, whereas 131 students underwent the typical rotation. The experience consisted of observing a faculty member conduct a comprehensive encounter on a new outpatient...
June 13, 2017: Neurology
https://www.readbyqxmd.com/read/28602414/the-older-adult-with-locoregionally-advanced-head-and-neck-squamous-cell-carcinoma-knowledge-gaps-and-future-direction-in-assessment-and-treatment
#15
REVIEW
Ronald Maggiore, Zachary S Zumsteg, Karlynn BrintzenhofeSzoc, Kelly M Trevino, Ajeet Gajra, Beatriz Korc-Grodzicki, Joel B Epstein, Stewart M Bond, Ira Parker, Julie A Kish, Barbara A Murphy, Noam A VanderWalde
Older adults with head and neck squamous cell carcinoma (HNSCC) pose unique treatment and supportive care challenges to oncologists and other cancer care providers. The majority of patients with HNSCC present with locoregionally advanced disease, for which combined-modality treatment integrating chemotherapy and radiation therapy is often necessary to maximize tumor control. However, applying these approaches to an older population with concomitant comorbidities and a higher risk of functional impairments remains challenging and is exacerbated by the paucity of studies involving older adults...
July 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28561649/mastering-resilience-in-oncology-learn-to-thrive-in-the-face-of-burnout
#16
REVIEW
Fay J Hlubocky, Miko Rose, Ronald M Epstein
Oncology clinician burnout has become a noteworthy issue in medical oncology directly affecting the quality of patient care, patient satisfaction, and overall organizational success. Due to the increasing demands on clinical time, productivity, and the evolving medical landscape, the oncology clinician is at significant risk for burnout. Long hours in direct care with seriously ill patients/families, limited control over daily responsibilities, and endless electronic documentation, place considerable professional and personal demands on the oncologist...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28552193/the-trio-framework-conceptual-insights-into-family-caregiver-involvement-and-influence-throughout-cancer-treatment-decision-making
#17
REVIEW
Rebekah Laidsaar-Powell, Phyllis Butow, Cathy Charles, Amiram Gafni, Vikki Entwistle, Ronald Epstein, Ilona Juraskova
OBJECTIVE: Family caregivers are regularly involved in cancer consultations and treatment decision-making (DM). Yet there is limited conceptual description of caregiver influence/involvement in DM. To address this, an empirically-grounded conceptual framework of triadic DM (TRIO Framework) and corresponding graphical aid (TRIO Triangle) were developed. METHODS: Jabareen's model for conceptual framework development informed multiple phases of development/validation, incorporation of empirical research and theory, and iterative revisions by an expert advisory group...
November 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28506538/epitope-specific-immunotherapy-targeting-cd4-positive-t-cells-in-coeliac-disease-two-randomised-double-blind-placebo-controlled-phase-1-studies
#18
Gautam Goel, Tim King, A James Daveson, Jane M Andrews, Janakan Krishnarajah, Richard Krause, Gregor J E Brown, Ronald Fogel, Charles F Barish, Roger Epstein, Timothy P Kinney, Philip B Miner, Jason A Tye-Din, Adam Girardin, Juha Taavela, Alina Popp, John Sidney, Markku Mäki, Kaela E Goldstein, Patrick H Griffin, Suyue Wang, John L Dzuris, Leslie J Williams, Alessandro Sette, Ramnik J Xavier, Ludvig M Sollid, Bana Jabri, Robert P Anderson
BACKGROUND: A gluten-free diet is the only means to manage coeliac disease, a permanent immune intolerance to gluten. We developed a therapeutic vaccine, Nexvax2, designed to treat coeliac disease. Nexvax2 is an adjuvant-free mix of three peptides that include immunodominant epitopes for gluten-specific CD4-positive T cells. The vaccine is intended to engage and render gluten-specific CD4-positive T cells unresponsive to further antigenic stimulation. We assessed the safety and pharmacodynamics of the vaccine in patients with coeliac disease on a gluten-free diet...
July 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28466666/european-and-russian-physician-awareness-of-best-management-approaches-for-infections-due-to-antibiotic-resistant-gram-negative-bacteria
#19
Paurus Irani, Tehseen Salimi, Robert Epstein, Megan Leone-Perkins, Ronald Aubert, Mona Khalid, Emma Epstein, J Russell Teagarden
OBJECTIVES: The rapid spread of infections due to antibiotic-resistant, Gram-negative bacteria in Europe and surrounding regions requires a heightened level of awareness among physicians within their practice settings. METHODS: We surveyed 800 physicians who treat these infections across France, Germany, Spain, Italy, and Russia to assess their awareness of best management approaches. RESULTS: We found that more than two-thirds do not consider themselves highly aware of best management practices...
August 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28349411/what-s-the-opposite-of-burnout
#20
Ronald M Epstein
No abstract text is available yet for this article.
July 2017: Journal of General Internal Medicine
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