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https://www.readbyqxmd.com/read/29474192/characterization-of-chemical-constituents-of-human-sweat-a-study-based-on-indian-population
#1
Aafrinnaz Moulvi, Pooja Minz, Subrata Rath, Richa Ashma
There is a strong evidence in the literature that human odor is unique to an individual; therefore, the focus of this study was to strengthen this evidence through the testing of sweat samples on unrelated individuals with the same ethnicity. Sweat samples were collected from 42 unrelated Indian males and females residing in the same city to determine the chemical constituents in human sweat. The volatile compounds of sweat were subsequently analyzed and identified using gas chromatography-mass spectrometry, and a National Institute of Standards and Technology library was used for individual profiling...
February 23, 2018: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/29472169/malignant-hidradenocarcinoma-in-the-lower-extremity-a-case-report-of-a-rare-tumor
#2
Brendan Kane, Evan Adler, Tarun Bhandari, Michael Rose, Nicola DiGuglielmo, Xiu Sun
Malignant hidradenocarcinomas are rare soft tissue tumors of sweat gland origin. We present the case of a soft tissue, fungating tumor of 15 years' duration of the medial ankle in an 85-year-old male that exhibited malignant features clinically and radiographically. Subsequent punch biopsy revealed a diagnosis of malignant hidradenocarcinoma. Given the risk of recurrence and the poor radiation and chemotherapy options, the patient initially decided to leave the lesion untreated. However, he soon developed lower extremity cellulitis from the exposed lesion and decided to have the tumor excised, eliminating the source of the infection...
February 19, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29471280/stretchable-wireless-system-for-sweat-ph-monitoring
#3
Wenting Dang, Libu Manjakkal, William Taube Navaraj, Leandro Lorenzelli, Vincenzo Vinciguerra, Ravinder Dahiya
Sensor-laden wearable systems that are capable of providing continuous measurement of key physiological parameters coupled with data storage, drug delivery and feedback therapy have attracted huge interest. Here we report a stretchable wireless system for sweat pH monitoring, which is able to withstand up to 53% uniaxial strain and more than 500 cycles to 30% strain. The stretchability of the pH sensor patch is provided by a pair of serpentine-shaped stretchable interconnects. The pH sensing electrode is made of graphite-polyurethane composite, which is suitable for biosensor application...
February 10, 2018: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29469738/dermatologic-manifestations-of-acromegaly-a-case-in-point-and-a-focused-review
#4
Ece Nur Degirmentepe, Sule Gungor, Emek Kocaturk, Utkan Kiziltac, Mine Adas, Selver Ozekinci, Amor Khachemoune
Acromegaly is a systemic syndrome caused by overproduction of growth hormone. Cutaneous, endocrine, cardiovascular, skeletal, and respiratory systems are affected. Cutaneous changes in acromegaly relate to overexpression of growth hormone and insulin-like growth factor 1 on skin cells and adnexa. Dermal glycosaminoglycan accumulation and edema cause skin distention that is most prominent in the face, hands, and feet. Oily skin with large pores, hypertrichosis, and excessive sweating are common features. Pigmented skin tags, acanthosis nigricans, and psoriasis are also encountered...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469728/generalized-eruptive-syringomas
#5
Amy Huang, Gina Taylor, Tracey N Liebman
Eruptive syringoma is a rare variant of syringoma, benign neoplasms of the eccrine sweat ducts that appear on the face, neck, chest, and axillae of predominately Asian and African American women before or during puberty [1, 2]. Lesions appear as small skin-colored or slightly pigmented, flat-topped papules [2]. The condition can be cosmetically disfiguring and difficult to treat, especially in dark-skinned patients. The investigators report a 52-year old Guyanese woman who presented with widespread, chronic, non-pruritic and nontender, skin-colored papules that arose approximately 20 years earlier...
September 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29468166/suspicion-of-postanesthetic-femoral-paralysis-of-the-non-dependent-limb-in-a-horse
#6
Alessandro Mirra, Micaël David Klopfenstein Bregger, Olivier Louis Levionnois
A 15-year-old Selle Francais gelding was presented to the equine referral hospital for treatment of a left guttural pouch mycosis previously diagnosed. After induction, the horse was shortly hoisted by all four feet, moved on a padded surgical table, and positioned in right lateral recumbency. In order to reduce the risk of bleeding during surgical manipulation of the carotid and maxillary arteries, a mean arterial pressure between 60 and 70 mmHg was targeted. After surgery, the horse was moved in a padded recovery box keeping the same lateral recumbency...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29464384/versajet-assisted-hydraulic-epilation-through-small-incisions-for-axillary-osmidrosis
#7
Jin Ho Han, June-Kyu Kim, Kun Chul Yoon, Hyun Woo Shin
BACKGROUND: Osmidrosis is a malodorous disease caused by the breakdown of sweat secreted from the apocrine glands by surface bacteria. The aim of this study was to evaluate the effect of Versajet-assisted hydraulic epilation for the treatment of axillary osmidrosis. METHODS: Thirty-two patients with axillary osmidrosis (64 axillae) underwent Versajet-assisted hydraulic epilation between January 2016 and January 2017. Subjective assessments were evaluated by a patient survey at least 3 months after the procedure...
February 20, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29464177/tb-or-not-tb-mycobacterium-celatum-mimicking-mycobacterium-tuberculosis-a-case-of-mistaken-identity
#8
Michael Chavarria, Larry Lutwick, Bonny L Dickinson
Mycobacterium celatum is a slow-growing, non-tuberculous mycobacterium (NTM) and a rare cause of infection in humans. Infection occurs primarily by inhalation or direct inoculation from environmental sources, and this pathogen has been reported to cause localized infections in the lungs and lymph nodes of both immunocompetent and immunocompromised patients, and disseminated disease in immunocompromised patients. Here, we present a case of pulmonary infection with M. celatum in an immunocompetent 68-year-old male with clinical features similar to tuberculosis...
2018: IDCases
https://www.readbyqxmd.com/read/29463352/precooling-and-warm-up-effects-on-time-trial-cycling-during-heat-stress
#9
Ramzi A Al-Horani, Jonathan E Wingo, Jason Ng, Phillip Bishop, Mark Richardson
BACKGROUND: Heat stress limits endurance exercise performance. Combining precooling and warm-up prior to endurance exercise in the heat may exploit the benefits of both strategies while avoiding the potential negative consequences of each. This study tested the hypothesis that precooling combined with warm-up improves time trial cycling performance in the heat relative to either treatment alone. METHODS: Nine healthy men completed three 16.1-km time trials in 33°C after: 1) precooling (ice slurry and ice vest) alone (PREC); 2) warm-up alone (WU); or 3) PREC plus WU (COMBO)...
February 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29461905/a-case-and-literature-review-of-orbital-microcystic-adnexal-carcinoma
#10
Alexander J Brent, Sundeep S Deol, Ram Vaidhyanath, Gerald Saldanha, Raghavan Sampath
Microcystic adnexal carcinoma (MAC) is a very rare and locally aggressive sweat gland tumour. MAC has been well reported presenting as a periocular cutaneous lesion, rarely with subsequent direct orbital invasion and only once as a primary orbital lesion. Local recurrence is frequent after primary surgical excision and the role of adjuvant radiotherapy is ill-defined. We describe a case of orbital MAC treated successfully with radiotherapy after incomplete margin clearance post exenteration surgery and review the associated literature...
February 20, 2018: Orbit
https://www.readbyqxmd.com/read/29461870/randomized-double-blind-crossover-study-of-the-adhesiveness-of-two-formulations-of-rotigotine-transdermal-patch-in-patients-with-parkinson-s-disease
#11
Jan-Peer Elshoff, Lars Bauer, Nadine Goldammer, Marga Oortgiesen, Hanna Pesch, Lars Timmermann
OBJECTIVE: In patch-based transdermal drug delivery, adhesiveness is critical for safe and effective treatment, especially in Parkinson's disease (PD) where excessive sweating is common. This study compared the adhesiveness of two transdermal patch formulations of rotigotine (improved room temperature-stable [PR2.3.1/Treatment A] and intermediate cold storage product [PR2.1.1/Treatment B]), using the largest patch size (40 cm2 ). METHODS: PD0018 (NCT02230904) was a multicenter, randomized, double-blind, crossover study...
February 20, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29460624/multifunctional-nickel-phosphate-nano-micro-flakes-3d-electrode-for-electrochemical-energy-storage-non-enzymatic-glucose-and-sweat-ph-sensors
#12
Narayanasamy Padmanathan, Han Shao, Kafil M Razeeb
Multifunctional, low-cost electrode and catalyst are desirable for next generation electrochemical energy storage and sensor applications. In this study, we demonstrate the fabrication of Ni3(PO4)2·8H2O nano/micro flakes layer on nickel foam (NF) by a facile one-pot hydrothermal approach and investigated this electrode for multiple applications including sweat based glucose and pH sensor as well as hybrid energy storage device, e. g., supercapattery. The electrode displays a specific capacity of 301.8 mAh g-1 (1552 F g-1) at an applied current of 5 mA cm-2 and able to retain 84% of its initial capacity after 10,000 cycles...
February 20, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29460300/catheter-associated-venous-air-embolism-in-hospitalized-horses-32-cases
#13
Nicholas J Parkinson, Harold C McKenzie, Michelle H Barton, Jennifer L Davis, Bettina Dunkel, Amy L Johnson, Elizabeth S MacDonald
BACKGROUND: Venous air embolism is a potentially life-threatening complication of IV catheter use in horses. Despite widespread anecdotal reports of their occurrence, few cases have been reported in the literature and the prognosis is currently unknown. HYPOTHESIS/OBJECTIVES: Our objective was to describe the surrounding circumstances, clinical signs, treatment, progression, and outcome of venous air embolism in hospitalized horses. ANIMALS: Thirty-two horses with acute onset of compatible clinical signs associated with IV catheter disconnection or damage...
February 20, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29460105/the-importance-of-standardisation-of-measurement-and-reference-intervals-for-detection-of-phaeochromocytoma-and-paraganglioma-ppgl
#14
REVIEW
Tomás P Griffin, Delia Bogdanet, Patrick Navin, Grace Callagy, Paula M O'Shea, Marcia Bell
A 51-year-old male presented 25 years ago with excessive sweating and haematuria. Blood pressure was labile. CT abdomen showed a large right-sided adrenal mass. Two 24-h urine collections showed elevated urinary catecholamines. Right adrenal resection was performed; a phaeochromocytoma (PC) was confirmed histologically. Two decades later, the patient represented with excessive sweating and measured variable blood pressure readings. Measurement of plasma metanephrines (PMets) showed elevated normetanephrine (NMN) [50,250 (R...
February 19, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29459303/the-human-skin-as-a-sub-thz-receiver-does-5g-pose-a-danger-to-it-or-not
#15
Noa Betzalel, Paul Ben Ishai, Yuri Feldman
In the interaction of microwave radiation and human beings, the skin is traditionally considered as just an absorbing sponge stratum filled with water. In previous works, we showed that this view is flawed when we demonstrated that the coiled portion of the sweat duct in upper skin layer is regarded as a helical antenna in the sub-THz band. Experimentally we showed that the reflectance of the human skin in the sub-THz region depends on the intensity of perspiration, i.e. sweat duct's conductivity, and correlates with levels of human stress (physical, mental and emotional)...
February 16, 2018: Environmental Research
https://www.readbyqxmd.com/read/29451946/first-experience-in-switzerland-in-phe508del-homozygous-cystic-fibrosis-patients-with-end-stage-pulmonary-disease-enrolled-in-a-lumacaftor-ivacaftor-therapy-trial-preliminary-results
#16
Christian Murer, Lars Christian Huber, Thomas Kurowski, Astrid Hirt, Cécile A Robinson, Urs Bürgi, Christian Benden
AIMS OF THE STUDY: Cystic fibrosis is the most common genetic disorder in Caucasians. The combination of the cystic fibrosis transmembrane conductance regulator (CFTR) corrector lumacaftor / potentiator ivacaftor (LUM/IVA) has been shown to increase forced expiratory volume in 1 second (FEV1) moderately, but predominantly reduce acute exacerbation rate (AER) in Phe508del homozygous cystic fibrosis patients; however, patients with FEV1 <40% predicted were excluded from studies. We used LUM/IVA on a "compassionate use" basis in cystic fibrosis patients with end-stage pulmonary disease...
February 16, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29447045/a-four-channel-electrical-impedance-spectroscopy-module-for-cortisol-biosensing-in-sweat-based-wearable-applications
#17
Devangsingh Sankhala, Sriram Muthukumar, Shalini Prasad
A four-channel electrochemical impedance spectroscopy (EIS) analyzer module has been demonstrated on flexible chemi-impedance sensors fabricated with gold electrodes for wearable applications. The module can perform time division multiplexed (TDM) impedance measurements on four sensors at 1 kHz. In this work, we characterize the system for the detection of cortisol in an ultralow volume (1-3 µL) of perspired human sweat, sensor performance, and effects during continuous cortisol dosing and with pH and temperature variations expected on the surface of the skin that would be representative of use conditions as seen by a wearable device...
February 1, 2018: SLAS Technology
https://www.readbyqxmd.com/read/29444631/accumulation-of-laforin-and-other-related-proteins-in-canine-lafora-disease-with-epm2b-repeat-expansion
#18
James K Chambers, Atigan Thongtharb, Takanori Shiga, Daigo Azakami, Miyoko Saito, Masumi Sato, Motoji Morozumi, Hiroyuki Nakayama, Kazuyuki Uchida
Canine Lafora disease (LD) is an autosomal recessive genetic disorder causing nonfatal structural epilepsy, mainly affecting miniature wirehaired dachshunds. Repeat expansion in the EPM2B gene causes a functional impairment of the ubiquitin ligase malin which regulates glycogen metabolism. Abnormally structured glycogen accumulates and develop polyglucosan bodies predominantly in the central nervous system. The authors performed a comprehensive clinical, genetic, and pathological study of 4 LD cases affecting miniature wirehaired dachshund dogs with EPM2B repeat expansions, with systemic distribution of polyglucosan bodies and accumulation of laforin and other functionally associated proteins in the polyglucosan bodies...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29443738/hodgkin-lymphoma-involving-the-tonsil-misdiagnosed-as-tonsillar-carcinoma-a-case-report-and-review-of-the-literature
#19
You Qin, Lijuan Lu, Yanwei Lu, Kunyu Yang
RATIONALE: Primary Hodgkin lymphoma (HL) involving the tonsil is extremely rare. Only about 20 such cases with verification of biopsy and immunohistochemistry have been reported. Because of its rarity and unremarkable clinical presentation, a timely correct diagnosis is very challenging. PATIENT CONCERNS: A 43-year-old man complained left tonsillar enlargement and painless masses in left neck, with night sweat. The clinical examination found a marked tonsillar asymmetry, with an enlarged left tonsil and ipsilateral cervical lymphadenopathy and a normal right tonsil...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29439398/a-real-time-wireless-sweat-rate-measurement-system-for-physical-activity-monitoring
#20
Andrew Brueck, Tashfin Iftekhar, Alicja B Stannard, Kumar Yelamarthi, Tolga Kaya
There has been significant research on the physiology of sweat in the past decade, with one of the main interests being the development of a real-time hydration monitor that utilizes sweat. The contents of sweat have been known for decades; sweat provides significant information on the physiological condition of the human body. However, it is important to know the sweat rate as well, as sweat rate alters the concentration of the sweat constituents, and ultimately affects the accuracy of hydration detection...
February 10, 2018: Sensors
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