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https://www.readbyqxmd.com/read/28644156/clinical-case-of-the-month-a-57-year-old-man-with-an-axillary-mass
#1
Palak Desai, Andrew Myers, Brian Boulmay, Fred A Lopez
A 57-year-old man presented to the surgical oncology clinic with a mildly tender mass under his right arm. Four years prior, the patient had a melanoma removed from his right shoulder along with an ipsilateral right axillary sentinel lymph sampling. Computed tomography (CT) scan was negative for metastatic disease at that time. The patient did not undergo completion axillary node dissection and was lost to follow-up. The patient was originally from Australia, did not tan but reported multiple sunburns before age 18...
May 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28643685/-disseminated-interdigitating-dendritic-cell-sarcoma
#2
Ignacio M Santarelli, Mariano Veltri, Diego J Manzella, María Alejandra Avagnina, Pablo M Pereyra, Hernán C Chavín
A 70 year-old woman was admitted to our hospital with a 3-month history of abdominal pain, weight loss and night sweats. On physical examination, she presented with a 5 cm diameter abdominal mass extended from epigastrium to the left flank, and at least three bilateral supraclavicular adenopathies. A disseminated interdigitating dendritic cell sarcoma was diagnosed through a biopsy of the abdominal mass. After that, a CHOP regime (cyclophosphamide, doxorubicin, vincristine and prednisone) was iniciated. She died after completion of the first cycle of treatment, six months after diagnosis...
2017: Medicina
https://www.readbyqxmd.com/read/28625163/gamma-delta-%C3%AE-%C3%AE-t-cell-lymphoma-another-case-unclassifiable-by-world-health-organization-classification-a-case-report
#3
Hemant Sindhu, Ruqin Chen, Hui Chen, Jonathan Wong, Rashid Chaudhry, Yin Xu, Jen C Wang
BACKGROUND: We present a case of gamma-delta T-cell lymphoma that does not fit the current World Health Organization classifications. CASE PRESENTATION: A 74-year-old Caribbean-American woman presented with lymphocytosis, pruritus, and non-drenching night sweats. Bone marrow and peripheral blood analyses both confirmed the diagnosis of gamma-delta T-cell lymphoma. An axillary lymph node biopsy was negative for lymphoma. Clinically absent hepatosplenomegaly and skin lesions with biopsy-proven gamma-delta T-cell lymphoma suggest that she is unclassifiable within the current classification system...
June 19, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28599946/a-58-year-old-man-with-fatigue-weight%C3%A2-loss-and-diffuse-miliary-pulmonary%C3%A2-opacities
#4
Udit Chaddha, Rebekah English, Jessica Daniels, Rajat Walia, Atul C Mehta, Tanmay S Panchabhai
A 58-year-old man presented with a 6-month history of profound fatigue and a weight loss of 35 to 40 pounds. He reported occasional night sweats and mildly painful knees and elbows without swelling or redness. He denied respiratory symptoms, rashes, or fevers. He had no respiratory symptoms. The patient's history was significant for rheumatoid arthritis (with arthralgias and joint involvement), paroxysmal atrial fibrillation, and hypothyroidism. His medications included digoxin and metoprolol. He had been taking methotrexate and low-dose prednisone (5 mg) for approximately 10 years but discontinued taking these medications 2 years prior to current presentation...
June 2017: Chest
https://www.readbyqxmd.com/read/28592459/the-effects-of-10-days-of-separate-heat-and-hypoxic-exposure-on-heat-acclimation-and-temperate-exercise-performance
#5
Rebecca A Neal, Jamie Prout, Joseph Costello, Heather C Massey, Michael J Tipton, John S Young, Jo Corbett
Adaptations to heat and hypoxia are typically studied in isolation, but are often encountered in combination. Whether the adaptive response to multiple stressors affords the same response as when examined in isolation is unclear. We examined: i) the influence of overnight moderate normobaric hypoxia on the time course and magnitude of adaption to daily heat exposure; ii) whether heat acclimation (HA) was ergogenic and if this was influenced by an additional hypoxic-stimulus. Eight males (V̇O2max=58.5[8.3] mL·kg(-1)·min(-1)) undertook two 11-day HA programmes (balanced-crossover design), once with overnight normobaric hypoxia (8[1] h per night; 10 nights; FIO2=0...
June 7, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28588156/clinical-presentation-of-adult-pulmonary-tuberculosis-ptb-a-study-of-103-cases-from-a-tertiary-care-hospital
#6
T K Barman, S Roy, M A Hossain, G R Bhuiyan, S Abedin
Tuberculosis, one of the oldest diseases known to affect humans, is a major cause of death worldwide. The disease, which is caused by the bacteria Mycobacterium tuberculosis complex, usually affects the lungs, although other organs are involved in up to one-third of causes. If properly treated, tuberculosis caused by drug-susceptible strains is curable in virtually all cases. If untreated, the disease may be fatal within five years in 50-65% of cases. Transmission usually takes place through the airborne spread of droplet nuclei produced by patients with infectious pulmonary tuberculosis...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28578604/does-palliative-chemotherapy-provide-a-palliative-effect-on-symptoms-in-late-palliative-stages-an-interview-study-with-oncologists
#7
Peter Strang, Jenny Bergqvist
BACKGROUND: The possible chemotherapy effects on symptoms in late stages of palliative chemotherapy are seldom registered in clinical practice or investigated as primary outcomes. The aim was therefore to study physicians' opinions and experiences about chemotherapy effects on symptoms. MATERIAL AND METHODS: Thirty-five physicians (mainly oncologists) with variation as regards age, gender and experience were included in a qualitative study with semi-structured interviews...
June 3, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28572226/a-clinical-enigma-of-ongoing-constrictive-pericarditis
#8
Deacon Zhao Jun Lee, Reshma Amin, John Baksi, Robert Gerber
A 59-year-old lady presented with a 1-week history of orthopnoea, paroxysmal nocturnal dyspnoea, night sweats and a productive cough. She had no recent history of travel. Transthoracic echocardiogram revealed preserved left ventricular systolic function with abnormal pericardial thickening and restrictive left ventricular filling consistent with pericardial constriction. Cardiac magnetic resonance imaging confirmed a globally thickened pericardium and showed evidence of pericardial inflammation and constrictive physiology...
June 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28566417/fascioliasis-a-rare-cause-of-hepatic-nodules
#9
Helena Temido, Manuel Oliveira-Santos, Francisco Parente, Lèlita Santos
Fascioliasis is a zoonotic disease that can sometimes affect humans. It presents with non-specific signs and symptoms which makes it difficult to establish an early definitive diagnosis. This can be particularly true in non-endemic countries where a high degree of suspicion is needed to make the diagnosis. Another confounding factor is that many of the initial complains and findings are very similar to those of malignancy. We report a case of an otherwise healthy 47 year-old male presenting with abdominal pain, night-time sweating, anorexia, weight loss and loose stools that had several hepatic nodules visible in the abdominal CT scan...
May 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28561959/review-of-efficacy-of-complementary-and-alternative-medicine-treatments-for-menopausal-symptoms
#10
REVIEW
Thea R Moore, Rachel B Franks, Carol Fox
Complementary and alternative medicine (CAM) treatments have been used for thousands of years around the world. There has been increased interest in utilizing CAM for menopausal symptoms since the release of results of the Women's Health Initiative elucidated long-term adverse effects associated with hormone therapy. Women looking for more natural or safer means to treat hot flushes, night sweats, and other menopausal symptoms often turn to CAM such as yoga, phytoestrogens, or black cohosh. Yet there have been few well-conducted studies looking at the efficacy of these treatments...
May 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28559756/multimodal-care-in-the-management-of-a-patient-with-chronic-tendinopathy-of-the-biceps-femoris-a-case-report
#11
Brett R Martin
OBJECTIVE: The purpose of this case report was to describe the use of dry needling in conjunction with auricular acupuncture, core exercises, and light aerobic activity for treating chronic tendinopathy of the biceps femoris. CLINICAL FEATURES: A 30-year-old white female presented with chronic biceps femoris tendinopathy. The injury had occurred 18 months prior while training for a triathlon. Active stretching of her right biceps femoris while standing with her feet 6 inches apart aggravated the pain at the origin in the right tendon of the biceps femoris at 0 degrees of movement...
June 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/28546801/the-safety-and-tolerance-of-phytotherapies-in-menopausal-medicine-a-review-of-the-literature
#12
REVIEW
Piotr Czuczwar, Tomasz Paszkowski, Marek Lisiecki, Sławomir Woźniak, Anna Stępniak
Phytoestrogens are polyphenol, non-steroidal substances of plant origin, resembling 17β-estradiol in structure. These substances can act as either agonists or antagonists of oestrogen receptors α and β. Phytoestrogens are widely used to alleviate menopausal symptoms, such as hot flushes and night sweats. Most of the currently available products of plant origin registered to soften climacteric symptoms consist of extracts obtained from soy, red clover, or black cohosh. Non-hormonal phytotherapy is a new alternative for patients suffering from menopausal symptoms...
March 2017: Przeglad Menopauzalny, Menopause Review
https://www.readbyqxmd.com/read/28544906/development-of-a-harmonized-patient-reported-outcome-questionnaire-to-assess-myelofibrosis-symptoms-in-clinical-trials
#13
Chad Gwaltney, Jean Paty, Virginia E Kwitkowski, Ruben A Mesa, Amylou C Dueck, Elektra J Papadopoulos, Lixia Wang, Joseph Feliciano, Stephen Joel Coons
Along with reducing spleen size, relieving symptom severity is a key objective of the treatment of myelofibrosis (MF). Several questionnaires have been developed for patient self-report of MF symptoms in clinical trials and each includes unique instructions, items, and/or response scales. This variability in questionnaire content increases uncertainty; it is unclear which questionnaire is the most appropriate for assessing MF symptoms and it makes comparisons across trials difficult. The Patient-Reported Outcome (PRO) Consortium's MF Working Group (WG) was established to review existing MF symptom questionnaires and to develop a harmonized, consensus-based PRO questionnaire for use in future MF trials...
May 12, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28528614/multifocal-tuberculosis-verrucosa-cutis-a-manifestation-extraordinary-of-reactivation-secondary-tuberculosis
#14
Virendra N Sehgal, Prashant Verma, Sambit N Bhattacharya, Sonal Sharma, Navjeevan Singh
A BCG (Bacillus Calmette-Guérin)-vaccinated 78-year-old man, a native Indian, reported with numerous asymptomatic, peanut-sized, dirty gray, elevated eruptions of 1 year's duration appearing over apparently normal skin on the upper and lower extremities (Figure 1). The onset of the eruptions had been sudden, but they had progressed slowly. A history of cough and/or expectoration, evening rise of temperature, night sweats, or loss of appetite and weight was denied.
2017: Skinmed
https://www.readbyqxmd.com/read/28516249/-a-67-year-old-man-with-fever-night-sweat-and-ascites
#15
A Hiseni-Kamberi, W-D Maier, K Junker, M Argirov
A 67-year-old man presented with fever, night sweat and abdominal complaints for about 4 weeks. Ultrasound and a computed tomography scan showed distinct ascites as the main finding, presenting as exsudate with predominating lymphoid cells. Because of long-term immunosuppressive therapy with the tumor necrosis factor (TNF)-α inhibitor golimumab for psoriasis, the suspicion for a possible tuberculous peritonitis arose. This was confirmed with an enzyme-linked immunospot assay, a high level of adenosine deaminase in the ascites and a peritoneum which was studded with multiple whitish nodules, corresponding to granulomas with giant cells...
May 17, 2017: Der Internist
https://www.readbyqxmd.com/read/28511822/posttraumatic-stress-disorder-ptsd-and-the-dermatology-patient
#16
Madhulika A Gupta, Patricia Jarosz, Aditya K Gupta
Dermatologic symptoms can be associated with posttraumatic stress disorder (PTSD) in several situations: (1) as features of some core PTSD symptoms, such as intrusion symptoms manifesting as cutaneous sensory flashbacks, as autonomic arousal manifesting as night sweats and idiopathic urticaria, and as dissociation manifesting as numbness and dermatitis artefacta; (2) the cutaneous psychosomatic effects of emotional and physical neglect and sexual abuse (eg, infantile eczema, cutaneous self-injury, and body-focused repetitive behaviors such as trichotillomania and skin picking disorder) and eating disorders, which can have dermatologic effects; (3) the direct effect of physical or sexual abuse or catastrophic life events (eg, earthquakes) on the skin; and (4) as a result of significant alterations in hypothalamic-pituitary-adrenal and sympatho-adrenal medullary axes, which can affect neuroendocrine and immune functions, and can lead to exacerbations of stress-reactive inflammatory dermatoses such as psoriasis, chronic urticaria, and atopic dermatitis...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28499938/allogeneic-stem-cell-transplantation-in-myelofibrosis
#17
REVIEW
Tania Jain, Ruben A Mesa, Jeanne M Palmer
Myeloproliferative neoplasm (MPN) is a category in the World Health Organization classification of myeloid tumors. BCR-ABL1-negative MPN is a subcategory that includes primary myelofibrosis (MF), post-essential thrombocythemia MF, and post-polycythemia vera MF. These disorders are characterized by stem cell-derived clonal myeloproliferation. Clinically, these diseases present with anemia and splenomegaly and significant constitutional symptoms such as severe fatigue, symptoms associated with an enlarged spleen and liver, pruritus, fevers, night sweats, and bone pain...
May 10, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28473914/isolated-splenic-abscess-in-brucellosis
#18
Sreenivasa Rao Sudulagunta, Monica Kumbhat, Mahesh Babu Sodalagunta, Aravinda Settikere Nataraju, Shiva Kumar Bangalore Raja
Brucellosis is a zoonotic infectious disease, which can attack any organ of the body but mainly involves lymphoreticular system. Our case report describes isolated splenic abscess diagnosed in a 50-year-old individual who is a milk vendor by occupation and has the habit of consuming raw milk. He was admitted with pain abdomen, high-grade fever with chills, generalized malaise, night sweats and weight loss. Ultrasound and computerized tomography of the abdomen showed splenomegaly and hypodense, nonenhancing lesion measuring 3...
February 2017: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/28472898/the-relation-among-steroid-hormone-levels-lipid-profile-and-menopausal-symptom-severity
#19
Cihan Kaya, Hüseyin Cengiz, Ali Yeşil, Murat Ekin, Levent Yaşar
INTRODUCTION: Many postmenopausal women experience hot flashes, night sweats, non-specific emotional and psychological distresses. Our aim was to investigate the relation among steroid hormone levels, lipid profile and menopausal symptom severity using the menopause rating scale (MRS). METHODS: A cross-sectional study was performed at our outpatient clinic with natural postmenopausal women. A total of 444 women were included in this study. The basic characteristics of the study population, such as age, gravidity, parity, time to menopause onset and body mass index (BMI) were recorded...
May 4, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28459892/severe-headache-neck-pain-intermittent-cough-%C3%A2-dx
#20
Claudia Lyon, Swapna Sayeneni, Jeanne Carey
A 32-year-old Chinese woman sought care from our family medicine clinic because she had a headache, neck pain, and an intermittent cough that had produced white sputum for 7 days. She described the headache as severe and pressure-like, and said that it had progressively worsened over the previous 3 weeks, coinciding with her first trip outside of China to the United States. The patient indicated that she also had occasional vomiting, dizziness, a low-grade fever, chills, night sweats, and increasing fatigue...
May 2017: Journal of Family Practice
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