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https://www.readbyqxmd.com/read/28634691/modulation-of-rotavirus-severe-gastroenteritis-by-the-combination-of-probiotics-and-prebiotics
#1
REVIEW
Guadalupe Gonzalez-Ochoa, Lilian K Flores-Mendoza, Ramona Icedo-Garcia, Ricardo Gomez-Flores, Patricia Tamez-Guerra
Annual mortality rates due to infectious diarrhea are about 2.2 million; children are the most vulnerable age group to severe gastroenteritis, representing group A rotaviruses as the main cause of disease. One of the main factors of rotavirus pathogenesis is the NSP4 protein, which has been characterized as a viral toxin involved in triggering several cellular responses leading to diarrhea. Furthermore, the rotavirus protein NSP1 has been associated with interferon production inhibition by inducing the degradation of interferon regulatory factors IRF3, IRF5, and IRF7...
June 20, 2017: Archives of Microbiology
https://www.readbyqxmd.com/read/28627061/glycaemic-and-insulinaemic-responses-of-adult-healthy-warm-blooded-mares-following-feeding-with-jerusalem-artichoke-meal
#2
M Glatter, M Bochnia, F Goetz, J Gottschalk, G Koeller, N Mielenz, D Hillegeist, J M Greef, A Einspanier, A Zeyner
This study aimed to investigate the impact of the supplementation of a pre-biotic compound [Jerusalem artichoke meal (JAM)] on the glycaemic and insulinaemic response in healthy, non-obese warm-blooded horses. Six adult mares [mean body weight (bwt) 529 ± 38.7 kg; body condition score 5.1 ± 0.49/9] were used. In two equal meals per day, the horses received crushed oat grains (1 g starch/kg bwt per day) and meadow hay (2 kg/100 kg bwt per day) which together were likely to meet the energy recommendation for light work (GfE, )...
June 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28618173/inter-individual-differences-determine-the-outcome-of-wheat-bran-colonization-by-the-human-gut-microbiome
#3
Kim De Paepe, Frederiek-Maarten Kerckhof, Joran Verspreet, Christophe M Courtin, Tom Van de Wiele
Gut microbiota research reveals a vital role for the luminal and mucosal gut microbiota in human health. Fewer studies, however, have characterized the microbiome associated with undigested, insoluble dietary particles in the gut. These particles can act as a food source for bacteria and offer a physical platform to which they can attach. In this study, the microbiome colonizing wheat bran particles was analyzed. In a batch experiment, wheat bran particles were separately incubated with the fecal microbiota derived from ten donors and washed after 48h to remove loosely attached bacteria...
June 15, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28616072/the-advanced-strategy-for-enhancing-biobutanol-production-and-high-efficient-product-recovery-with-reduced-wastewater-generation
#4
Chuang Xue, Xiaotong Zhang, Jufang Wang, Min Xiao, Lijie Chen, Fengwu Bai
BACKGROUND: Butanol as an important chemical and potential fuel could be produced via ABE fermentation from lignocellulosic biomass. The use of food-related feedstocks such as maize and sugar cane may not be a sustainable solution to world's energy needs. Recently, Jerusalem artichoke tubers containing inulin have been used as feedstock for butanol production, but this bioprocess is not commercially feasible due to the great value of inulin as functional food. Till now, there is a gap on the utilization of Jerusalem artichoke stalk (JAS) as feedstock for microbial butanol production...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28596023/prebiotic-reduces-body-fat-and-alters-intestinal-microbiota-in-children-with-overweight-or-obesity
#5
Alissa C Nicolucci, Megan P Hume, Inés Martínez, Shyamchand Mayengbam, Jens Walter, Raylene A Reimer
BACKGROUND & AIMS: It might be possible to manipulate the intestinal microbiota with prebiotics or other agents to prevent or treat obesity. However, little is known about the ability of prebiotics to specifically modify gut microbiota in children with overweight/obesity or reduce body weight. We performed a randomized controlled trial to study the effects of prebiotics on body composition, markers of inflammation, bile acids in fecal samples, and composition of the intestinal microbiota in children with overweight or obesity...
June 3, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28594860/effect-of-probiotic-lactobacillus-on-lipid-profile-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#6
Yucheng Wu, Qingqing Zhang, Yin Ren, Zhongbao Ruan
OBJECTIVE: To assess the efficacy of probiotic Lactobacillus on serum lipids using a meta-analysis of randomized, controlled trials. METHODS: Fifteen studies containing 15 trials, with 976 subjects were included. The pooled WMD was calculated by random effects model. RESULTS: Probiotic Lactobacillus consumption significantly reduced TC by 0.26mmol/l (95% CI, -0.40 to -0.12) and LDL-C by 0.23mmol/l (95% CI, -0.36 to -0.10). Subgroup analysis of trials found significantly reduction of TC using L...
2017: PloS One
https://www.readbyqxmd.com/read/28590342/supplementation-of-low-and-high-fat-diets-with-fermentable-fiber-exacerbates-severity-of-dss-induced-acute-colitis
#7
Jennifer P Miles, Jun Zou, Matam-Vijay Kumar, Michael Pellizzon, Edward Ulman, Matthew Ricci, Andrew T Gewirtz, Benoit Chassaing
BACKGROUND: Lack of dietary fiber has been suggested to increase the risk of developing various chronic inflammatory diseases, whereas supplementation of diets with fiber might offer an array of health-promoting benefits. Consistent with this theme, we recently reported that in mice, compositionally defined diets that are made with purified ingredients and lack fermentable fiber promote low-grade inflammation and metabolic syndrome, both of which could be ameliorated by supplementation of such diets with the fermentable fiber inulin...
July 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28586546/a-bioartificial-environment-for-kidney-epithelial-cells-based-on-a-supramolecular-polymer-basement-membrane-mimic-and-an-organotypical-culture-system
#8
Björne B Mollet, Iven L J Bogaerts, Geert C van Almen, Patricia Y W Dankers
Renal applications in healthcare, such as renal replacement therapies and nephrotoxicity tests, could potentially benefit from bioartificial kidney membranes with fully differentiated and functional human tubular epithelial cells. A replacement of the natural environment of these cells is required to maintain and study cell functionality cell differentiation in vitro. Our approach was based on synthetic supramolecular biomaterials to mimic the natural basement membrane (BM) on which these cells grow and a bioreactor to provide the desired organotypical culture parameters...
June 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28586162/chain-length-dependent-effects-of-inulin-type-fructan-dietary-fiber-on-human-systemic-immune-responses-against-hepatitis-b
#9
Leonie M Vogt, Marlies E Elderman, Theo Borghuis, Bart J de Haan, Marijke M Faas, Paul de Vos
SCOPE: In vivo studies demonstrating that only specific dietary-fibers contribute to immunity are still inconclusive, as measuring immune effects in healthy humans remains difficult. We applied a relatively inefficacious vaccination-challenge to study chain length-dependent effects of inulin-type fructan (ITF) dietary fibers on human immunity. METHODS AND RESULTS: ITFs with two different 'degree of polymerization-' (DP)-profiles were tested in vitro for effects on PBMC-cytokines and TLR2 activation...
June 6, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28583137/protective-effects-of-synbiotic-diets-of-bacillus-coagulans-lactobacillus-plantarum-and-inulin-against-acute-cadmium-toxicity-in-rats
#10
Dornoush Jafarpour, Seyed Shahram Shekarforoush, Hamid Reza Ghaisari, Saeed Nazifi, Javad Sajedianfard, Mohammad Hadi Eskandari
BACKGROUND: Cadmium is a heavy metal that causes oxidative stress and has toxic effects in humans. The aim of this study was to investigate the influence of two probiotics along with a prebiotic in preventing the toxic effects of cadmium in rats. METHODS: Twenty-four male Wistar rats were randomly divided into four groups namely control, cadmium only, cadmium along with Lactobacillus plantarum (1 × 109 CFU/day) and inulin (5% of feedstuff) and cadmium along with Bacillus coagulans (1 × 109 spore/day) and inulin (5% of feedstuff)...
June 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28580332/enhancement-of-toxic-substances-clearance-from-blood-equvalent-solution-and-human-whole-blood-through-high-flux-dialyzer-by-1-mhz-ultrasound
#11
M B Shiran, M Barzegar Marvasti, A Shakeri-Zadeh, M Shahidi, N Tabkhi, F Farkhondeh, E Kalantar, A Asadinejad
BACKGROUND: Hemodialysis is a process of removing waste and excess fluid from blood when kidneys cannot function efficiently. It often involves diverting blood to the filter of the dialysis machin to be cleared of toxic substances. Fouling of pores in dialysis membrane caused by adhesion of plasma protein and other toxins will reduce the efficacy of the filtre. OBJECTIVE: In This study, the influence of pulsed ultrasound waves on diffusion and the prevention of fouling in the filter membrane were investigated...
June 2017: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/28578041/microbiota-source-impact-in-vitro-metabolite-colonic-production-and-anti-proliferative-effect-of-spent-coffee-grounds-on-human-colon-cancer-cells-ht-29
#12
Angélica María Hernández-Arriaga, B Dave Oomah, Rocio Campos-Vega
Human gut flora-mediated non-digestible fraction of spent coffee grounds (hgf-NDSCG) was evaluated for its chemopreventive effect and molecular mechanisms involved on human colon adenocarcinoma HT-29 cell survival using two different microbiota source [lean (L) and overweight (OW)]. The source of human gut flora (hgf) (L or OW) affected the pH of hgf-NDSCG only minimally, but linearly reduced those of hgf-inulin. The variability between lean and overweight microbiota was characterized by the metabolism and/or bioaccessibility of different phenolic metabolites, their intermediate and end products as well as by variable time courses...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28578032/processing-rheological-properties-of-wheat-flour-dough-and-bread-containing-high-levels-of-soluble-dietary-fibres-blends
#13
S Arufe, H Chiron, J Doré, I Savary-Auzeloux, L Saulnier, G Della Valle
Wheat flour doughs were processed with soluble dietary fibres (DF) added up to 40% (w/w flour). DF were made of a ternary mixture of maltodextrins (MT, 3/5), pectins (PE, 1/5) and inulin (IN, 1/5). The addition of DF decreased the specific mechanical energy developed by the mixer, mainly because of water addition. It increased the ratio of storage moduli and the elongational viscosity of the dough, but decreased the strain hardening index. Energy input and rheological changes at mixing largely explained the decreases of porosity characteristic time and stability time during fermentation...
July 2017: Food Research International
https://www.readbyqxmd.com/read/28575959/multifunctional-inulin-tethered-silver-graphene-quantum-dots-nanotheranostic-module-for-pancreatic-cancer-therapy
#14
Preeti Nigam Joshi, Sachin Agawane, Meghana C Athalye, Vrushali Jadhav, Dhiman Sarkar, Rajiv Prakash
Cancer nanotechnology is an emerging area of cancer diagnosis and therapy. Although considerable progress has been made for targeted drug delivery systems to deliver anticancer agents to particular site of interest, new nanomaterials are frequently being developed and explored for better drug delivery efficiency. In the present work, we have explored a novel nanoformulation based on silver-graphene quantum dots (Ag-GQDs) nanocomposite for its successful implementation for pancreatic cancer specific drug delivery in wistar rats...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28560515/stimulating-effects-of-sucrose-and-inulin-on-growth-lactate-and-bacteriocin-productions-by-pediococcus-pentosaceus
#15
Pamela Oliveira de Souza de Azevedo, Attilio Converti, José Manuel Domínguez, Ricardo Pinheiro de Souza Oliveira
Sucrose and inulin, when combined with glucose, behaved as stimulating agents of bacteriocin production by Pediococcus pentosaceus ATCC 43200. When such microbial strain was grown in glucose-based Man, Rogosa, and Sharpe (MRS) medium, without any additional supplement, it showed higher maximum cell concentration (2.68 ± 1.10 g/L) and longer generation time (2.17 ± 0.02 h), but lower specific growth rate (0.32 ± 0.01 h(-1)) than in the same medium supplemented with 1.0% of both ingredients (2.53 ± 1...
May 30, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28559623/rheological-properties-of-reduced-fat-ice-cream-mix-containing-octenyl-succinylated-pearl-millet-starch
#16
Monika Sharma, Ashish K Singh, Deep N Yadav
The octenyl succinyl anhydride (OSA) esterified pearl millet (Pennisetum typhoides) starch was evaluated as fat replacer in soft serve ice cream in comparison to other fat replacers viz. inulin, whey protein concentrate-70 and commercial starch. During temperature sweep test, the yield stress and flow behaviour index of un-pasteurized ice cream mixes increased as the temperature increased from 40 to 80 °C, while the consistency index decreased. Consistency index of aged ice cream mixes containing 2% fat replacer was higher as compared to mixes with 1% level...
May 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28559592/gut-microbiota-inulin-regulates-endothelial-function-a-prebiotic-smoking-gun
#17
Francesca Fava, Kieran M Tuohy
No abstract text is available yet for this article.
May 31, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28555924/physical-mechanical-characterization-of-cosmetic-formulations-and-correlation-between-instrumental-measurements-and-sensorial-properties
#18
Lívia Salomão Calixto, Patrícia M B G Maia Campos
OBJECTIVE: The correct choice of raw materials in the development of cosmetic formulations is essential for obtaining stable and pleasant skin care products. Therefore, rheological, texture and sensory analyses are important to understand the behavior and stability of the formulations. In this context, the aim of the present study was to develop cosmetic formulations containing or not (vehicle) UV filters and chicory root extract, to evaluate their stability as well as to characterize their physical and texture properties and correlate them with the sensory attributes...
May 28, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28552770/synbiotic-loaded-chitosan-ca-alginate-microparticles-reduces-inflammation-in-the-tnbs-model-of-rat-colitis
#19
Tanja Petreska Ivanovska, Kristina Mladenovska, Zoran Zhivikj, Maja Jurhar Pavlova, Ivica Gjurovski, Trpe Ristoski, Lidija Petrushevska-Tozi
New therapeutic strategies against inflammatory bowel disease (IBD) consider the usage of probiotics, prebiotics and synbiotics as beneficial for the intestinal microbial balance. Limitations of such an approach are addressed into difference in survival, persistence, colonization and variable effects among different probiotic strains, lack in understanding of probiotic mechanisms of action, as well the complex etiology of IBD. The anti-inflammatory activity of Lactobacillus casei 01 (L. casei 01) was assessed in trinitrobenzenesulphonic (TNBS) acid model of rat colitis when the probiotic was used alone and/or in combination with oligofructose-enriched inulin (Synergy 1), and as synbiotic (L...
May 25, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28548573/inulin-type-fructan-degradation-capacity-of-clostridium-cluster-iv-and-xiva-butyrate-producing-colon-bacteria-and-their-associated-metabolic-outcomes
#20
F Moens, L De Vuyst
Four selected butyrate-producing colon bacterial strains belonging to Clostridium cluster IV (Butyricicoccus pullicaecorum DSM 23266(T) and Faecalibacterium prausnitzii DSM 17677(T)) and XIVa (Eubacterium hallii DSM 17630 and Eubacterium rectale CIP 105953(T)) were studied as to their capacity to degrade inulin-type fructans and concomitant metabolite production. Cultivation of these strains was performed in bottles and fermentors containing a modified medium for colon bacteria, including acetate, supplemented with either fructose, oligofructose, or inulin as the sole energy source...
May 30, 2017: Beneficial Microbes
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