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Friedriechs ataxia

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https://www.readbyqxmd.com/read/24632794/modeling-inherited-cardiac-disorders
#1
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Karim Sallam, Kazuki Kodo, Joseph C Wu
Advances in the understanding and treatment of cardiac disorders have been thwarted by the inability to study beating human cardiac cells in vitro. Induced pluripotent stem cells (iPSCs) bypass this hurdle by enabling the creation of patient-specific iPSC-derived cardiomyocytes (iPSC-CMs). These cells provide a unique platform to study cardiac diseases in vitro, especially hereditary cardiac conditions. To date, iPSC-CMs have been used to successfully model arrhythmic disorders, showing excellent recapitulation of cardiac channel function and electrophysiologic features of long QT syndrome types 1, 2, 3, and 8, and catecholaminergic polymorphic ventricular tachycardia (CPVT)...
2014: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/14172029/heart-in-friedriech-s-ataxia
#2
T M MCCALLA, F A HASKINS
No abstract text is available yet for this article.
September 19, 1964: British Medical Journal (1857-1980)
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