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Elizabeth R Smith, Yue Meng, Robert Moore, Jeffrey D Tse, Arn G Xu, Xiang-Xi Xu
BACKGROUND: Nuclear size and shape are specific to a cell type, function, and location, and can serve as indicators of disease and development. We previously found that lamin A/C and associated nuclear envelope structural proteins were upregulated when murine embryonic stem (ES) cells differentiated to primitive endoderm cells. Here we further investigated the morphological changes of nuclei that accompany this differentiation. RESULTS: The nuclei of undifferentiated wild type cells were found shaped as flattened, irregular ovals, whereas nuclei of Gata4-positive endoderm cells were more spherical, less flattened, and with a slightly reduced volume...
January 14, 2017: BMC Cell Biology
Christina Balderrama-Durbin, Kimberley Stanton, Douglas K Snyder, Jeffrey A Cigrang, G Wayne Talcott, Amy M Smith Slep, Richard E Heyman, Daniel G Cassidy
Military deployment can create significant relationship strain. Although most couples navigate the challenges of deployment successfully, this period may render some couples more vulnerable to adverse relationship outcomes such as infidelity due to a convergence of factors including geographic separation and reduced emotional and physical intimacy. Despite anecdotal reports of increased rates of infidelity during deployment, empirical findings are lacking. This study used a prospective design to examine the prevalence and risk factors of infidelity across the deployment cycle including a year-long deployment to Iraq...
January 5, 2017: Journal of Family Psychology: JFP
Alexander W Cheesman, Lucas A Cernusak
The isotopic composition of leaf water in terrestrial plants is highly dependent upon a plant's environment. This isotopic signature can become integrated into organic molecules, allowing the isotopic composition of biomarkers such as cellulose to be used as sensitive paleo and climatic proxies. However, the mechanisms by which cellulose isotopic composition reflect environmental conditions are complex, and may vary between leaf and woody tissues. To date few empirical tests have been made on the relative roles of leaf-water enrichment and source water on the isotopic composition of leaf and wood cellulose within the same plant...
December 21, 2016: Tree Physiology
Laura C Funk, Lauren M Zasadil, Beth A Weaver
Errors in chromosome segregation during mitosis have been recognized as a hallmark of tumor cells since the late 1800s, resulting in the long-standing hypothesis that mitotic abnormalities drive tumorigenesis. Recent work has shown that mitotic defects can promote tumors, suppress them, or do neither, depending on the rate of chromosome missegregation. Here we discuss the causes of chromosome missegregation, their effects on tumor initiation and progression, and the evidence that increasing the rate of chromosome missegregation may be an effective chemotherapeutic strategy...
December 19, 2016: Developmental Cell
David Rodrigues, Diniz Lopes, C Veronica Smith
Sociosexuality refers to individual differences in interest and willingness to engage in sexual activity without an emotional connection. Unrestricted sociosexuality is associated with a greater likelihood of infidelity and with poorer relationship quality. However, previous research has failed to examine relationship-specific characteristics that may moderate these findings. Two studies of romantically involved adults examined whether relationship commitment and different relationship agreement types moderate the associations between unrestricted sociosexuality and infidelity...
December 2, 2016: Journal of Sex Research
Ali Ismail, Jawed A Mallick, Dahui Qin, Mohammad O Hussaini
AIM: To report the first case of a Richter syndrome where small lymphocytic lymphoma (SLL) progressed to a CD3+ diffuse large B-cell lymphoma (DLBCL). METHODS: Macrodissection of small and large cell lymphomatous components was performed. This was followed by flow cytometric analysis along with molecular B-cell immunoglobulin (heavy and light chains) and T-cell receptor (γ and β chains) gene rearrangement studies to investigate a clonal relationship between the components...
November 29, 2016: Journal of Clinical Pathology
Maria Giuseppina Pacilli, Stefano Pagliaro, Steve Loughnan, Sarah Gramazio, Federica Spaccatini, Anna Costanza Baldry
This paper examines the influence of female sexualization on people's willingness to provide help in cases of intimate partner violence (IPV). We examined how sexualization may make women seem lacking moral patiency and moral virtue both of which may lead to a reduced willingness to help. In the first study, participants read a fictitious newspaper article describing an IPV incident. They were then presented with a picture of the ostensible victim depicting the woman with either a sexualized or non-sexualized appearance...
November 2, 2016: British Journal of Social Psychology
Gladys E Ibañez, Elaine Whitt, Tenesha Avent, Steve S Martin, Leah M Varga, Miguel A Cano, Daniel J O'Connell
OBJECTIVES: Latina women are disproportionately affected by HIV in the US, and account for 30% of all HIV infections in Miami-Dade County, Florida. The main risk for Latina women is heterosexual contact. Little is known about the relational and cultural factors that may impact women's HIV risk perception. This study aims to describe Latina women's perception of their HIV risk within a relational, cultural, and linguistic context. DESIGN: Eight focus groups of Latina women (n = 28), four English speaking groups and four Spanish speaking groups, were conducted between December 2013 and May 2014...
October 21, 2016: Ethnicity & Health
Brunhild Kring
No abstract text is available yet for this article.
November 16, 2016: Journal of Sex & Marital Therapy
Anna M F Harts, Isobel Booksmythe, Michael D Jennions
In many birds, males are presumed to protect their paternity by closely guarding their mate or copulating frequently with her. Both these costly behaviors are assumed to reduce the risk and/or intensity of sperm competition. However, despite many studies on avian extra-pair paternity, it remains unclear how strongly these behaviors are related to fitness and other key life-history traits. Here, we conduct meta-analyses to address two questions. First, are mate guarding and/or frequent copulation positively correlated with a male's share of paternity at his nest? We find a significant positive correlation between both presumed paternity protection behaviors and paternity share...
October 7, 2016: Evolution; International Journal of Organic Evolution
Benjamin L Compton, Jonathan M Bowman
For individuals in exclusive romantic relationships, the dynamics of sexual experimentation are nuanced. Extradyadic behavior outside of a relationship may be perceived as cheating or infidelity, with much of those perceptions driven by the biological sex of the perceiver. This study significantly reframes seminal research on perceptions of cheating with third-party friends by Kruger et al. (2013), to further nuance an evolutionary threat-based model. In doing so, this furthers our understanding of the associated perceptions of individuals in heterosexual relationships when confronted by partners' cheating with their same-sex cross-orientation friends...
October 5, 2016: Journal of Homosexuality
Mark A Stillman, Tyler Brown, Eva C Ritvo, Ira D Glick
The focus of this paper is to provide an update on the use of psychotherapy as a treatment in sport psychiatry, and the use of this approach to address common psychiatric issues encountered with this population. Specifically, family therapy, individual therapy, and group psychotherapy prescribed alone, or in combination with medication, will be examined as methods to manage issues/disorders often associated with athletes. These include obsessive-compulsive rituals and perfectionism, and aggressive and risky behaviours, such as gambling, infidelity, substance use, and suicidal ideation, narcissism, and aggression in the context of individual and team competitive sports...
August 12, 2016: International Review of Psychiatry
C J Ballance, T P Harty, N M Linke, M A Sepiol, D M Lucas
We demonstrate laser-driven two-qubit and single-qubit logic gates with respective fidelities 99.9(1)% and 99.9934(3)%, significantly above the ≈99% minimum threshold level required for fault-tolerant quantum computation, using qubits stored in hyperfine ground states of calcium-43 ions held in a room-temperature trap. We study the speed-fidelity trade-off for the two-qubit gate, for gate times between 3.8  μs and 520  μs, and develop a theoretical error model which is consistent with the data and which allows us to identify the principal technical sources of infidelity...
August 5, 2016: Physical Review Letters
David Rodrigues, Diniz Lopes
Sociosexuality refers to a personal predisposition to engage in uncommitted sex. Romantically involved individuals are more likely to engage in infidelity when more unrestricted in their sociosexuality and less committed to their current partners. However, commitment reliably predicts relationship maintenance and the activation of pro-relationship behaviors, regardless of sociosexuality levels. In two studies (Study 1: N = 566 heterosexuals; M age = 21.24, SD = 4.45; Study 2: N = 168 heterosexuals; M age = 23...
July 27, 2016: Archives of Sexual Behavior
Keith M Harris, Elias Aboujaoude
Online relationships are increasingly central to many people's lives. As a result, there is a growing need to scientifically examine their psychosocial implications. This study developed and tested the Online Relationship Initiation Scale (ORIS) through classical and item response theory analyses to address this need. An anonymous online survey included 713 adults, aged 18-71 years. The ORIS was tested on psychometric properties and examined for associations with gender and several standardized psychosocial measures...
August 2016: Cyberpsychology, Behavior and Social Networking
Bin Wu, Bethany Vallangeon, Jonathan Galeotti, Siby Sebastian, Catherine Rehder, Endi Wang
Expression of CD3 on a mature B cell neoplasm, such as diffuse large B cell lymphoma (DLBCL), is extremely rare. When it is present, it will cause diagnostic confusion since the classification of lymphoid neoplasms is largely based on immunophenotyping to determine the cell lineage. We report three cases of DLBCL with CD3 and other T cell-associated antigens. A literature search identifies 30 additional cases of DLBCL expressing CD3, with the majority (78.6 %) displaying cytoplasmic expression, while two of our cases demonstrate membranous staining...
October 2016: Annals of Hematology
Julia Schroeder, Yu-Hsun Hsu, Isabel Winney, Mirre Simons, Shinichi Nakagawa, Terry Burke
One predicted cost of female infidelity in socially monogamous species is that cuckolded males should provide less parental care. This relationship is robust across species, but evidence is ambiguous within species. We do not know whether individual males reduce their care when paired with cheating females compared with when paired with faithful females (within-male adjustment) or, alternatively, if the males that pair with cheating females are the same males that provide less parental care in general (between-male effect)...
August 2016: American Naturalist
Alexey Rozov, Natalia Demeshkina, Eric Westhof, Marat Yusupov, Gulnara Yusupova
The fidelity of translation depends strongly on the selection of the correct aminoacyl-tRNA that is complementary to the mRNA codon present in the ribosomal decoding center. The ribosome occasionally makes mistakes by selecting the wrong substrate from the pool of aminoacyl-tRNAs. Here, we summarize recent structural advances that may help to clarify the origin of missense errors that occur during decoding. These developments suggest that discrimination between tRNAs is based primarily on steric complementarity and shape acceptance rather than on the number of hydrogen bonds between the molding of the decoding center and the codon-anticodon duplex...
September 2016: Trends in Biochemical Sciences
M Dolores Gil-Llario, Cristina Giménez, Rafael Ballester-Arnal, Georgina Cárdenas-López, Ximena Durán-Baca
This study explores the relation between gender differences and sexuality among young Hispanic people. Eight hundred and forty young people from Spain and Mexico filled out a self-administered questionnaire about sexuality (sexual experience, sexual orientation, and sexual relationships) and gender (self-identification). Men in both Spain and Mexico more commonly report the practice of masturbation and vaginal sex, and are more likely to be unfaithful than women. Women in both countries report more steady partners and longer length of relationships...
July 1, 2016: Journal of Sex & Marital Therapy
David Rodrigues, Diniz Lopes, Marco Pereira
In sexually monogamous relationships (SMR), sociosexuality, or the predisposition to engage in extradyadic casual sex, is negatively associated with relationship outcomes. However, mutually consenting to sexually non-MR (SNMR) does not hinder relationship outcomes. Recent research has extended these findings to the phenomenon of online extradyadic sexual behavior. The aim of this study was to examine whether this sexual agreement moderates the association between sociosexuality and relationship satisfaction in a sample of romantically involved heterosexuals registered on a dating Web site directed at other romantically involved heterosexuals-Second Love...
June 2016: Cyberpsychology, Behavior and Social Networking
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