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https://www.readbyqxmd.com/read/29165592/folate-deficiency-induces-mitotic-aberrations-and-chromosomal-instability-by-compromising-the-spindle-assembly-checkpoint-in-cultured-human-colon-cells
#1
Xihan Guo, Juan Ni, Yuqian Zhu, Tao Zhou, Xiaoling Ma, Jinglun Xue, Xu Wang
Folates comprise the essential B9 vitamin that act as cofactors and cosubstrates in one-carbon metabolism for both biosynthesis and methylation of DNA and RNA. Folate deficiency (FD) has been shown to induce chromosomal instability (CIN), yet the underlying mechanisms are poorly understood. Here, we used human NCM460 colon mucosal cells as a model to investigate the effect of FD on spindle assembly checkpoint (SAC), a cell-cycle regulatory pathway preventing CIN during mitosis. Cells were maintained in medium containing 1...
November 19, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29121662/qualitative-and-quantitative-assessment-of-illumina-s-forensic-str-and-snp-kits-on-miseq-fgx%C3%A2
#2
Vishakha Sharma, Hoi Yan Chow, Donald Siegel, Elisa Wurmbach
Massively parallel sequencing (MPS) is a powerful tool transforming DNA analysis in multiple fields ranging from medicine, to environmental science, to evolutionary biology. In forensic applications, MPS offers the ability to significantly increase the discriminatory power of human identification as well as aid in mixture deconvolution. However, before the benefits of any new technology can be employed, a thorough evaluation of its quality, consistency, sensitivity, and specificity must be rigorously evaluated in order to gain a detailed understanding of the technique including sources of error, error rates, and other restrictions/limitations...
2017: PloS One
https://www.readbyqxmd.com/read/29096076/regulation-of-mrna-translation-in-neurons-a-matter-of-life-and-death
#3
REVIEW
Mridu Kapur, Caitlin E Monaghan, Susan L Ackerman
Dynamic regulation of mRNA translation initiation and elongation is essential for the survival and function of neural cells. Global reductions in translation initiation resulting from mutations in the translational machinery or inappropriate activation of the integrated stress response may contribute to pathogenesis in a subset of neurodegenerative disorders. Aberrant proteins generated by non-canonical translation initiation may be a factor in the neuron death observed in the nucleotide repeat expansion diseases...
November 1, 2017: Neuron
https://www.readbyqxmd.com/read/29090392/perceived-risk-of-intimate-partner-violence-among-sti-clinic-patients-implications-for-partner-notification-and-patient-delivered-partner-therapy
#4
Steven A John, Jennifer L Walsh, Young Ik Cho, Lance S Weinhardt
Patient-delivered partner therapy (PDPT) is the practice of providing patients diagnosed with a bacterial sexually transmitted infection (STI) medication to give directly to their partner for treatment without requiring the partner to participate in diagnostic testing and counseling. Despite a growing body of evidence in support of PDPT, literature is limited to date on the influence of perceived risk of intimate partner violence (IPV) on PDPT use. We analyzed mixed-method data from 196 quantitative surveys (61% male, M age = 31...
October 31, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29077548/jealousy-gender-and-culture-of-honor-a-study-in-portugal-and-brazil
#5
Jesús M Canto, José Luis Alvaro, Cícero Pereira, Alicia Garrido, Ana R Torres, Marcos Emanoel Pereira
The purpose of this study was to examine whether gender and culture of honor were associated with the type of infidelity (sexual or emotional) that affected our subjects more. Samples of 192 Portuguese university students (119 women and 73 men) and 415 Brazilian university students (214 men and 201 women) participated in this research. Participants responded to six dilemmas reflecting a type of infidelity (sexual or emotional), a gender scale, and a culture of honor scale. The results of both samples are compatible with the cultural theses about jealousy...
August 18, 2017: Journal of Psychology
https://www.readbyqxmd.com/read/29072437/from-love-and-fidelity-to-infidelity-individual-experiences-of-women-with-breast-cancer-regarding-relationships-with-their-spouses
#6
Hajar Nouri Sanchuli, Mozhgan Rahnama, Hossein Shahdadi, Mahdieh Poudineh Moghaddam
Background and Objective: Breast cancer and its treatment processes not only involve the patients but also their spouses and can impact on mutual relationships. Spouses of women with breast cancer may experience devastating consequences of the disease in their marital and sexual relationships. Therefore, in the present study we aimed to investigate individual experiences of women with breast cancer in their relationships with their spouses. Materials and Methods: This was a qualitative study with a conventional approach to content analysis...
October 26, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29058100/human-mating-theory-migration-and-marital-dissolution
#7
Roberto Ippoliti
Marriage dissolution has been extensively analyzed in the last few decades, looking for the determinants of this well-known phenomenon, but so far the relationship between female migration and marriage dissolution does not seem to have been thoroughly investigated. This work aimed to analyze the correlation between marriage dissolution and migration, which might bias the sex ratio within a given society, introducing new social and cultural values. Considering the Regions of Italy between 2002 and 2007 (i.e...
October 20, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29025484/-it-makes-the-patient-s-spirit-weaker-tuberculosis-stigma-and-gender-interaction-in-dar-es-salaam-tanzania
#8
C Miller, J Huston, L Samu, S Mfinanga, P Hopewell, E Fair
SETTING: Dar es Salaam, Tanzania. OBJECTIVES: To describe tuberculosis (TB) related stigma and to understand how it interacts with gender to affect access to care. DESIGN: Eight focus group discussions were held among 48 TB patients and their household members, and a thematic content analysis was carried out. RESULTS: The main components of stigma were fear, self-isolation, ostracization, loss of status in the community, and discrimination by providers...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28982311/-wtf-is-prep-attitudes-towards-pre-exposure-prophylaxis-among-men-who-have-sex-with-men-and-transgender-women-in-new-york-city
#9
Matthew Thomann, Ashley Grosso, Richard Zapata, Mary Ann Chiasson
In the USA, gay and other men who have sex with men and transgender women are disproportionately affected by HIV. Uptake of pre-exposure prophylaxis (PrEP), anti-retroviral therapy to prevent HIV-negative individuals from seroconverting if exposed to HIV, by members of this population remains low, particularly among African-Americans. We conducted two focus groups to assess responses to an online social media campaign focusing on PrEP use in New York City. We designed, produced and disseminated the campaign to address knowledge of PrEP; its physical and psychological side effects; and psychosocial barriers related to PrEP adherence and sex shaming...
October 6, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28949230/induced-cavities-for-photonic-quantum-gates
#10
Ohr Lahad, Ofer Firstenberg
Effective cavities can be optically induced in atomic media and employed to strengthen optical nonlinearities. Here we study the integration of induced cavities with a photonic quantum gate based on Rydberg blockade. Accounting for loss in the atomic medium, we calculate the corresponding finesse and gate infidelity. Our analysis shows that the conventional limits imposed by the blockade optical depth are mitigated by the induced cavity in long media, thus establishing the total optical depth of the medium as a complementary resource...
September 15, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28929303/the-facial-width-to-height-ratio-predicts-sex-drive-sociosexuality-and-intended-infidelity
#11
Steven Arnocky, Justin M Carré, Brian M Bird, Benjamin J P Moreau, Tracy Vaillancourt, Triana Ortiz, Nicole Marley
Previous research has linked the facial width-to-height ratio (FWHR) to a host of psychological and behavioral characteristics, primarily in men. In two studies, we examined novel links between FWHR and sex drive. In Study 1, a sample of 145 undergraduate students revealed that FWHR positively predicted sex drive. There were no significant FWHR × sex interactions, suggesting that FWHR is linked to sexuality among both men and women. Study 2 replicated and extended these findings in a sample of 314 students collected from a different Canadian city, which again demonstrated links between the FWHR and sex drive (also in both men and women), as well as sociosexuality and intended infidelity (men only)...
September 19, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28922011/south-asian-immigrant-women-s-suggestions-for-culturally-tailored-hiv-education-and-prevention-programs
#12
Roula N Hawa, Angela Underhill, Carmen H Logie, Shazia Islam, Mona Loutfy
Using a community-based, socialist feminist qualitative study, and an emergent research design, we explored the unique individual experiences of South Asian immigrant women living with HIV in the Greater Toronto Area (GTA) of Ontario, Canada. We assessed both the HIV risk context and the strategies for HIV education and prevention as expressed by study participants. Grounded in Connell's social theory of gender, a thematic analysis of semi-structured interviews with 12 women yielded six themes related to the power and impact of stigmatization, community's denial of HIV, infidelity, manifested in resistance to discussing sex and condom use, non-disclosure, and lack of HIV knowledge...
September 18, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/28885047/dating-infidelity-in-turkish-couples-the-role-of-attitudes-and-intentions
#13
Ezgi Toplu-Demirtaş, Frank D Fincham
Studies on dating infidelity have mostly been carried out in individualistic, Western cultures and have tended to investigate either attitudes or intentions toward infidelity in isolation from each other. The current study therefore investigated dating infidelity in a more collectivist, predominantly Muslim culture. Informed by the theory of planned behavior, it tested intentions as a potential mechanism that might account for the association between attitudes toward infidelity and reported infidelity. In doing so, the role of gender and infidelity history was also investigated in regard to attitudes and intentions toward infidelity...
September 8, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28882079/using-qualitative-methods-to-understand-perceptions-of-risk-and-condom-use-in-african-american-college-women-implications-for-sexual-health-promotion
#14
TyWanda L McLaurin-Jones, Maudry-Beverley Lashley, Vanessa J Marshall
BACKGROUND: Young African American women are disproportionately affected with sexually transmitted infections (STIs) and unintentional pregnancies. Despite adequate knowledge, assertiveness, and negotiation skills, consistent condom use remains low. AIMS: We sought to assess the role of pregnancy and STI risk perception in condom decision making among African American women. METHOD: We conducted a phenomenological qualitative study. Utilizing a purposive sampling strategy, 100 African American women (18-24 years) were recruited from a historically Black college and university for an open discussion of condom use...
October 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28873087/women-s-and-men-s-reports-of-past-year-prevalence-of-intimate-partner-violence-and-rape-and-women-s-risk-factors-for-intimate-partner-violence-a-multicountry-cross-sectional-study-in-asia-and-the-pacific
#15
Rachel Jewkes, Emma Fulu, Ruchira Tabassam Naved, Esnat Chirwa, Kristin Dunkle, Regine Haardörfer, Claudia Garcia-Moreno
BACKGROUND: Understanding the past-year prevalence of male-perpetrated intimate partner violence (IPV) and risk factors is essential for building evidence-based prevention and monitoring progress to Sustainable Development Goal (SDG) 5.2, but so far, population-based research on this remains very limited. The objective of this study is to compare the population prevalence rates of past-year male-perpetrated IPV and nonpartner rape from women's and men's reports across 4 countries in Asia and the Pacific...
September 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28862050/synthetic-cannabinoid-black-mamba-infidelity-in-patients-presenting-for-emergency-stabilization-in-colorado-a-p-scan-cohort
#16
Nicklaus Brandehoff, Axel Adams, Kyle McDaniel, Samuel D Banister, Roy Gerona, Andrew A Monte
BACKGROUND: Use of new psychoactive substances (NPS) has increased over the last decade. During this period, variability of both clinical presentations and chemical compositions of these compounds has increased. Synthetic cannabinoids (SCs) are the most commonly used NPS and there are more than 100 documented unique molecules in this class. "Black Mamba", often associated to ADB-FUBINACA, is the most commonly used SC in Colorado. It has been linked to kidney injury, myocardial toxicity, seizures, and death...
September 1, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28855884/consideration-of-cosmetic-surgery-as-part-of-women-s-benefit-provisioning-mate-retention-strategy
#17
Mohammad Atari, Nicole Barbaro, Yael Sela, Todd K Shackelford, Razieh Chegeni
Individuals perform mate retention behaviors to minimize the risk of partner infidelity and relationship dissolution. The current study investigates whether consideration of cosmetic surgery can be conceptualized as part of a broader strategy of mate retention for women, but not men. We hypothesized that women's consideration of cosmetic surgery would be positively associated with performance frequencies of Benefit-Provisioning and Cost-Inflicting mate retention behaviors. We recruited 203 individuals (54% women) in committed heterosexual relationships from Tehran, Iran...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28852250/delusion-of-triplet-pregnancy-in-abdominal-cavity-a-case-report-with-a-review-of-literature
#18
Shri Gopal Goyal, Ananya Mahapatra, Priti Kumari Goyal, Sudhir Kumar Khandelwal
The two terms, pseudocyesis and delusion of pregnancy, were frequently used for pseudopregnancy. Delusion of pregnancy is a special form of hypochondriacal/somatic delusion reported in various psychiatric and organic disorders. The origin of the delusion of pregnancy in schizophrenia has often been explained by psycho-analytic interpretations attributing wish fulfilling, protective role to false beliefs, and mother establishes an undisturbed union with her fetus during pregnancy, which eliminate loneliness and helplessness...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28832596/femicide-in-turkey-between-2000-and-2010
#19
Sadik Toprak, Gokhan Ersoy
Although intimate partner violence (IPV) is an important problem that threatens women's health, very few studies focus on the victim-perpetrator relationship or examine this relationship across Turkey. The aim of this study is to contribute to a better understanding of femicide cases in Turkey and to describe the socio-demographic, clinical, forensic, and criminological characteristics of femicide victims and offenders. This study analysed 162 femicide cases that occurred in 12 cities in Turkey from 1 January 2000 to 31 December 2010...
2017: PloS One
https://www.readbyqxmd.com/read/28813298/infidelity-in-romantic-relationships
#20
REVIEW
Frank D Fincham, Ross W May
This article summarizes the current state of research on the prediction of infidelity and provides a foundation for advancing knowledge on this topic by offering specific recommendations for future research. The prevalence, terminological diversity, and impact of infidelity on numerous indicators of wellness is first discussed. This is followed by a discussion of the individual, relationship, and contextual factors that have received systematic attention in attempting to predict infidelity. Highlights include various demographics, the closing gender gap, cohabitation, religion, and the role of the internet in facilitating infidelity...
February 2017: Current Opinion in Psychology
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