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lemierre syndrome anticoagulation

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https://www.readbyqxmd.com/read/27834169/persistent-fever-with-chills-and-an-endocardial-mass-in-a-child-an-unusual-presentation-of-hughes-stovin-syndrome
#1
Marianna Fabi, Francesca Lami, Maurizio Zompatori
A 12-year-old boy with a right atrium endocardial mass was initially diagnosed as having Lemierre's syndrome on the basis of previous mastoiditis and jugular vein and cerebral venous thrombosis. Lack of response to antibiotics, persistent high fever with chills, acute-phase reactants, and peripheral arterial pseudoaneurysms made us reconsider the diagnosis. Only after the late appearance of radiological pulmonary lesions and recognition of pulmonary artery aneurysms, Hughes-Stovin syndrome was diagnosed. Hughes-Stovin syndrome is an exceedingly rare vasculitis, especially in childhood, consisting of multiple pulmonary artery aneurysms and deep venous thromboses...
November 11, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27695351/lemierre-s-syndrome-current-perspectives-on-diagnosis-and-management
#2
REVIEW
Katrine M Johannesen, Uffe Bodtger
This is a systematic review of cases with Lemierre's syndrome (LS) in the past 5 years. LS is characterized by sepsis often evolving after a sore throat or tonsillitis and then complicated by various septic emboli and thrombosis of the internal jugular vein. Symptoms include sepsis, pain, and/or swelling in the throat or neck, as well as respiratory symptoms. Laboratory findings show elevated infectious parameters and radiological findings show thrombosis of the internal jugular vein and emboli in the lungs or other organs...
2016: Infection and Drug Resistance
https://www.readbyqxmd.com/read/27497400/to-anticoagulate-controversy-in-the-management-of-thrombotic-complications-of-head-neck-infections
#3
Jenna Rebelo, Smriti Nayan, Karen Choong, Martha Fulford, Anthony Chan, Doron D Sommer
OBJECTIVE: To review the thrombotic complications of head and neck infections, including Lemierre's syndrome, and their management. METHODS: A retrospective review of pediatric patients presenting to McMaster Children's Hospital from 2009 to 2013 was undertaken. The literature was reviewed for evidence regarding the use of anticoagulation therapy in this population. RESULTS: Eleven cases (6 males, 5 females) were identified. The median age was 10...
September 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27079502/efficacy-of-non-vitamin-k-antagonist-oral-anticoagulants-for-lemierre-syndrome
#4
Masayuki Kubota, Hiroaki Daidoji, Nobuhiro Takaya, Kurato Tokunaga, Tomohiro Sonoo, Kensuke Nakamura
No abstract text is available yet for this article.
March 18, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/26638515/-loco-regional-complications-of-pharyngitis-the-example-of-lemierre-s-syndrome
#5
J Tschopp, C Chuard
Pharyngitis is a common cause of consultation in ambulatory medicine. Although it is benign in most cases, serious complications may happen and must be recognized quickly. Lemierre's syndrome is one of them. It consists in the association of thrombosis of the internal jugular vein and septic emboli that generally involve the lungs and is classically associated with Fusobacterium necrophorum. It is usually found in young and healthy adults and has an estimated mortality of 5%. Diagnosis relies essentially on the characteristic presentation of the disease...
October 7, 2015: Revue Médicale Suisse
https://www.readbyqxmd.com/read/26279962/lemierre-s-syndrome-caused-by-klebsiella-pneumoniae-in-a-diabetic-patient-a-case-report-and-review-of-the-literature
#6
REVIEW
Alan Chuncharunee, Thana Khawcharoenporn
Lemierre's syndrome is characterized by an oropharyngeal infection with internal jugular vein thrombosis followed by metastatic infections in other organs. This infection is usually caused by Fusobacterium spp. In this report, we present a rare case of Klebsiella pneumoniae-associated Lemierre's syndrome in a patient with poorly-controlled diabetes mellitus. The infection was complicated by septic emboli in many organs, which led to the patient's death, despite combined antibiotics, anticoagulant therapy, and surgical intervention...
August 2015: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/26257787/lemierre-s-syndrome-a-neglected-disease-with-classical-features
#7
Andreas V Hadjinicolaou, Yiannis Philippou
We report the case of a previously healthy, immunocompetent 23-year-old male who presented to the Emergency Department with general malaise, difficulty in breathing, fever, and chest pain. He reported a two-week history of progressively worsening sore throat that he presumed to be a viral infection and thus initially neglected. However, when his condition deteriorated, he was admitted to hospital acutely unwell and in respiratory distress. He quickly developed septic shock requiring intensive care admission for inotropic support...
2015: Case Reports in Medicine
https://www.readbyqxmd.com/read/26175788/extensive-bilateral-lemierre-syndrome-due-to-methicillin-resistant-staphylococcus-epidermidis-in-a-patient-with-lung-adenocarcinoma
#8
Bo Mi Choi, Seong Wan Son, Chan Kwon Park, Sang-Hoon Lee, Hyung Kyu Yoon
Lemierre syndrome (LS) is a septic thrombophlebitis of the internal jugular vein (IJV) following an oropharyngeal infection. LS is commonly caused by normal anaerobic flora and treated with appropriate antibiotics and anticoagulation therapy. Although the incidence of disease is very rare, 15% cases of LS are fatal even in the antibiotic era because of disseminated septic thromboemboli. We reported a case of extensive bilateral LS due to methicillin-resistant Staphylococcus epidermidis in a 63-year-old female with lung adenocarcinoma...
July 2015: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/26041393/-a-case-with-both-infectious-cavernous-sinus-thrombosis-and-lemierre-syndrome-due-to-intraoral-resident-flora
#9
REVIEW
Akihiro Nishida, Toshiyasu Ogata, Masataka Kudo, Kousuke Fukuhara, Jiro Fukae, Yoshio Tsuboi
The present report describes a 54-year-old woman with cavernous sinus thrombosis (CST) presenting with fever, and marked periorbital swelling. There is a history of untreated periodontal disease. On initial examination, periorbital pain associated with bilateral blephaloptosis, chemosis, and disturbed eye movement was present. The laboratory evaluation showed significant elevations in inflammatory and fibrinolytic markers. Diffusion-weighted MRI revealed high signal intensities in the bilateral superior ophthalmic veins (SOV)...
2015: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/25692056/lemierre-s-syndrome-recognising-a-typical-presentation-of-a-rare-condition
#10
James A Coultas, Neena Bodasing, Paul Horrocks, Anthony Cadwgan
Lemierre's syndrome is a rare complication following an acute oropharyngeal infection. The aetiological agent is typically anaerobic bacteria of the genus Fusobacterium. The syndrome is characterised by a primary oropharyngeal infection followed by metastatic spread and suppurative thrombophlebitis of the internal jugular vein. If left untreated, Lemierre's syndrome carries a mortality rate of over 90%. Whilst relatively common in the preantibiotic era, the number of cases of Lemierre's syndrome subsequently declined with the introduction of antibiotics...
2015: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/25455045/lemierre-syndrome-and-the-role-of-modern-antibiotics-and-therapeutic-anticoagulation-in-its-treatment
#11
Michalis Agrafiotis, Evdokia Moulara, Diamantis Chloros, Venetia Tsara
No abstract text is available yet for this article.
May 2015: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/25410567/a-severe-case-of-lemierre-syndrome-with-streptococcus-constellatus-infection
#12
Midori Shimada, Yoshitomo Morinaga, Takeshi Kitazaki, Minoru Fukuda, Kohji Hashiguchi, Katsunori Yanagihara, Shigeru Kohno
A 76-year-old Japanese male presenting with high fever, headache, and disturbance of consciousness was hospitalized. Contrast computed tomography revealed thrombophlebitis in the internal jugular vein and abscesses in the posterior neck region, pharynx, and pterygoid muscle. Streptococcus constellatus infection was confirmed by culture of blood samples, and the patient was diagnosed with Lemierre syndrome. In addition to the administration of antibiotics and anticoagulants, abscess drainage was performed. S...
2014: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/25387698/septic-thrombosis-of-the-internal-jugular-vein-lemierre-s-syndrome-revisited
#13
Adrian D Schubert, Michel-André Hotz, Marco D Caversaccio, Andreas Arnold
OBJECTIVES/HYPOTHESIS: Study of the clinical evolution of a primary ear, nose, and throat infection complicated by septic thrombophlebitis of the internal jugular vein. STUDY DESIGN: Retrospective case-control study. PATIENTS AND METHODS: From 1998 to 2010, 23 patients at our institution were diagnosed with a septic thrombosis of the internal jugular vein. Diagnostics included microbiologic analysis and imaging such as computed tomography, magnetic resonance imaging, and ultrasound...
April 2015: Laryngoscope
https://www.readbyqxmd.com/read/24905121/case-review-lemierre-s-syndrome
#14
Jessica Asnani, Shawnet Jones
A previously healthy 35-year-old man with a one-week history of left-sided neck pain and fever as high as 104°F sought care at our emergency department. He was given a diagnosis of viral pharyngitis and discharged. He returned the next day and indicated that he was now experiencing drenching night sweats and weakness.
April 2014: Journal of Family Practice
https://www.readbyqxmd.com/read/24668238/lemierre-s-syndrome-with-double-heterozygote-status-in-the-methylenetetrahydrofolate-reductase-gene
#15
Mostafa Behpour-Oskooee, Abdollah Karimi, Shirin Sayyahfar
BACKGROUND: There are some risk factors being more vulnerable to Lemierre's syndrome such as a hypercoagulable state. METHODS: We report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis, bilateral mastoiditis, and sigmoid sinus thrombosis. RESULTS: Genetic study revealed a double heterozygote status in the methylenetetrahydrofolate reductase gene including C677T and A1298C. CONCLUSION: It is suggested to screen patients with Lemierre's syndrome for a hypercoagulable state to consider anticoagulant therapy...
August 2014: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/24436600/lemierre-syndrome-should-we-anticoagulate-a-case-report-and-review-of-the-literature
#16
C K Phua, V M Chadachan, R Acharya
Lemierre syndrome is an uncommon condition classically described in acute oropharyngeal infection with septic thrombophlebitis of the internal jugular vein and metastatic septic embolism particularly to the lungs. It is commonly described in young healthy adults with isolation of Fusobacterium necrophorum. We describe a case of Lemierre syndrome in a 50-year-old man with newly diagnosed diabetes mellitus presenting with a neck abscess secondary to Klebsiella pneumoniae. Our patient made good recovery to appropriate antimicrobial therapy, prompt surgical drainage, and anticoagulation...
June 2013: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/24152679/lemierre-s-syndrome
#17
Wesley Eilbert, Nitin Singla
Lemierre's syndrome is a condition characterized by thrombophlebitis of the internal jugular vein and bacteremia caused by primarily anaerobic organisms, following a recent oropharyngeal infection. This has been an uncommon illness in the era of antibiotic therapy, though it has been reported with increasing frequency in the past 15 years. Lemierre's syndrome should be suspected in young healthy patients with prolonged symptoms of pharyngitis followed by symptoms of septicemia or pneumonia, or an atypical lateral neck pain...
2013: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/24053095/-clinical-case-of-the-month-an-unusual-sepsis
#18
G Dubois, F Damas, V Fraipont
Lemierre's syndrome is a rare, but significant pathology to recognize. It most often affects young patients in good health; a late diagnosis can be fatal. It consists in an anaerobic septicemia (usually, Fusobacterium necrophorum) originating from a suppurative thrombophlebitis of the internal jugular vein. Infection occurs during a common sore throat and spreads by contiguity. The clinical presentation is a sepsis with pulmonary embolisations, but other sites of dissemination can also occur. Treatment consists of prolonged intravenous antibiotherapy associated with supportive therapy, if needed...
July 2013: Revue Médicale de Liège
https://www.readbyqxmd.com/read/23797007/lemierre-syndrome-from-a-neck-abscess-due-to-methicillin-resistant-staphylococcus-aureus
#19
Agarwal Abhishek, Singla Sandeep, Pandey Tarun
Lemierre syndrome is characterized by acute septic thrombophlebitis of the internal jugular vein (IJV) that develops after an oropharyngeal infection, and can be complicated by septic emboli to lungs and other organs. The most frequent causative agent is Fusobacterium necrophorum, an anaerobic bacillus found in normal oropharyngeal flora. Staphylococcus aureus has emerged as a cause of Lemierre syndrome in the last decade. We report a case of a 24-year-old man who developed septic IJV thrombosis and necrotizing pneumonia due to S...
July 2013: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/23710815/-lemierre-syndrome-caused-by-arcanobacterium-haemolyticum-a-case-report-and-review-of-the-literature
#20
REVIEW
Wen-han Zhang, Ying-qun Ji, Zhong-he Zhang
OBJECTIVE: To emphasize the importance of the early diagnosis and treatment of Lemierre syndrome caused by Arcanobacterium haemolyticum. METHOD: A case of Lemierre syndrome caused by Arcanobacterium haemolyticum and three similar reported cases were reviewed. RESULTS: A man complained of fever with a sore throat, and examination found an enlarged left tonsil with prominent exudate, normal blood routine test and chest radiograph. Although the patient received the treatment of penicillin G and azithromycin, his condition worsened...
January 2013: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
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