Rosa Klotz, Jan Larmann, Christina Klose, Thomas Bruckner, Laura Benner, Colette Doerr-Harim, Solveig Tenckhoff, Johan F Lock, Elmar-Marc Brede, Roberto Salvia, Enrico Polati, Jörg Köninger, Jan-Henrik Schiff, Uwe A Wittel, Alexander Hötzel, Tobias Keck, Carla Nau, Anca-Laura Amati, Christian Koch, Thomas Eberl, Michael Zink, Ales Tomazic, Vesna Novak-Jankovic, Stefan Hofer, Markus K Diener, Markus A Weigand, Markus W Büchler, Phillip Knebel
IMPORTANCE: Morbidity is still high in pancreatic surgery, driven mainly by gastrointestinal complications such as pancreatic fistula. Perioperative thoracic epidural analgesia (EDA) and patient-controlled intravenous analgesia (PCIA) are frequently used for pain control after pancreatic surgery. Evidence from a post hoc analysis suggests that PCIA is associated with fewer gastrointestinal complications. OBJECTIVE: To determine whether postoperative PCIA decreases the occurrence of gastrointestinal complications after pancreatic surgery compared with EDA...
July 1, 2020: JAMA Surgery