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https://www.readbyqxmd.com/read/27933555/pharmacist-s-comprehensive-geriatric-assessment-introduction-and-evaluation-at-elderly-patient-admission
#1
Faiza Rhalimi, Mounir Rhalimi, Alain Rauss
BACKGROUND: The role of the clinical pharmacist within the healthcare system remains unclear. OBJECTIVE: Our objective was to describe a pharmacist's comprehensive geriatric assessment (pCGA) at admission of elderly patients and to assess its relevance in terms of medication compliance and pharmacist interventions (PIs). METHODS: We conducted a prospective interventional study over 29 months in a 34-bed medical/rehabilitation geriatric ward in a French geriatric hospital...
December 8, 2016: Drugs—Real World Outcomes
https://www.readbyqxmd.com/read/27933417/on-the-characterization-of-the-heterogeneous-mechanical-response-of-human-brain-tissue
#2
Antonio E Forte, Stephen M Gentleman, Daniele Dini
The mechanical characterization of brain tissue is a complex task that scientists have tried to accomplish for over 50 years. The results in the literature often differ by orders of magnitude because of the lack of a standard testing protocol. Different testing conditions (including humidity, temperature, strain rate), the methodology adopted, and the variety of the species analysed are all potential sources of discrepancies in the measurements. In this work, we present a rigorous experimental investigation on the mechanical properties of human brain, covering both grey and white matter...
December 8, 2016: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/27933259/deformity-correction-and-extremity-lengthening-in-the-lower-leg-comparison-of-clinical-outcomes-with-two-external-surgical-procedures
#3
Eugen Reitenbach, Robert Rödl, Georg Gosheger, Björn Vogt, Frank Schiedel
OBJECTIVE: Distraction osteogenesis is a method of stimulating the growth of new bone tissue in order to lengthen the extremities or bridge resected bone defects. In addition to the now-established intramedullary procedures, two different fixator systems are in use. The present study investigated the classical Ilizarov ring fixator (IRF) and a hexapod to assess the precision of lower-leg lengthening and complications classified using the Paley criteria for problems, obstacles, and complications...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27933156/improving-the-accuracy-of-electronic-prescribing-in-west-bay-health-center-in-qatar
#4
Wafaa Yousuf, Sheren Elkomy, Mona Soliman, Noof Al-Mansouri, Mohamed Salem, Amal Al-Ali, Mohamed H Mahmoud, Hisham Elmahdi
Primary healthcare in Qatar uses electronic prescribing to reduce the risk of medication errors. Electronic prescribing is supported by computerized Physician Order Entry systems through Cerner (electronic medical record system). There are still prescription errors, despite electronic prescribing being in place for one year at West Bay Health Center. West Bay Health Center is a famous primary healthcare center in Qatar. It is a training center for the family medicine residency program, which is accredited by the accreditation council of general medical education international (ACGME-I)...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27932987/limits-of-applicability-of-the-voronoi-tessellation-determined-by-centers-of-cell-nuclei-to-epithelium-morphology
#5
Sara Kaliman, Christina Jayachandran, Florian Rehfeldt, Ana-Sunčana Smith
It is well accepted that cells in the tissue can be regarded as tiles tessellating space. A number of approaches were developed to find an appropriate mathematical description of such cell tiling. A particularly useful approach is the so called Voronoi tessellation, built from centers of mass of the cell nuclei (CMVT), which is commonly used for estimating the morphology of cells in epithelial tissues. However, a study providing a statistically sound analysis of this method's accuracy is not available in the literature...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27932405/dentoskeletal-effects-of-oral-appliance-wear-in-obstructive-sleep-apnoea-and-snoring-patients
#6
Giulio Alessandri-Bonetti, Vincenzo D'Antò, Chiara Stipa, Roberto Rongo, Serena Incerti-Parenti, Ambrosina Michelotti
OBJECTIVES: To evaluate the dentoskeletal changes associated with long-term and continuous mandibular advancement device (MAD) use in sleep-related breathing disorder patients. METHODS: Cephalometric measurements and three-dimensional model analysis were performed at baseline and after 3.5 ± 1.1 years in 20 snoring and obstructive sleep apnoea patients treated with the Silensor® appliance. Intra-group differences were compared using paired t-test or Wilcoxon signed-rank test...
December 8, 2016: European Journal of Orthodontics
https://www.readbyqxmd.com/read/27932125/survival-outcomes-in-liver-transplantation-with-elderly-donors-analysis-of-andalusian-transplant-register
#7
C Cepeda-Franco, C Bernal-Bellido, L Barrera-Pulido, J M Álamo-Martínez, J H Ruiz-Matas, G Suárez-Artacho, L M Marín-Gómez, J Tinoco-González, C Díaz-Aunión, F J Padillo-Ruiz, M Á Gómez-Bravo
Recently, there has been a large discrepancy between the number of patients on the waiting list for a liver transplant and the availability of deceased donors, with an increase in annual wait list mortality rates. Elderly donor livers are thought to be marginal grafts; however, in recent years, their utilization has constantly increased. The aim of this study is to evaluate the utilization of elderly donors in Andalusia and post-transplant outcomes. This retrospective observational study of 2408 liver transplants, performed in Andalusia between 2000 and 2014, analyzes the outcomes from donors aged 70 plus (n = 423) in terms of survival rates of the graft and the recipient, the type of transplant, donor age, and D-MELD score (product of donor age and preoperative Model for End-stage Liver Disease score)...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931996/changes-in-the-prevalence-of-cigarette-smoking-and-quitting-smoking-determinants-in-adult-inhabitants-of-rural-areas-in-poland-between-2003-and-2012
#8
B Sozańska, N Pearce, M Błaszczyk, A Boznański, P Cullinan
OBJECTIVES: We investigate trends in the prevalence of cigarette smoking among adults at all ages in two time points 9 years apart in two neighbouring rural populations and examine social and respiratory health determinants of quitting smoking. STUDY DESIGN: Repeated cross-sectional study. METHODS: Two cross-sectional surveys were conducted in the same rural area of lower Silesia in Poland in 2003 and 2012. A total of 1328 (91% of adult eligible individuals) in 2003 and 1449 (92% of eligible) in 2012 adult inhabitants were surveyed, 908 people (560 villagers and 348 town inhabitants) participated in both surveys...
December 2016: Public Health
https://www.readbyqxmd.com/read/27931719/a-potential-pitfall-in-evaluating-her2-immunohistochemistry-for-gastric-signet-ring-cell-carcinomas
#9
Chang Gok Woo, Won Jin Ho, Young Soo Park, Sook Ryun Park, Min-Hee Ryu, Hwoon-Yong Jung, Yoon-Koo Kang
Signet ring cell carcinoma (SRC) more commonly presents as metastatic disease and renders patients to be considered for chemotherapy. While treatment options are limited overall, trastuzumab has been shown to be effective for HER2 positive SRC cases. The current algorithm for HER2 evaluation heavily relies on positive membrane-specific staining by immunohistochemistry (IHC), but several anecdotal reports have suggested that SRCs may be susceptible to misinterpretation due to non-specific staining in the marginated cytoplasm with/without nucleus...
December 5, 2016: Pathology
https://www.readbyqxmd.com/read/27931256/comparison-of-marginal-fit-of-cemented-zirconia-copings-manufactured-after-digital-impression-with-lava%C3%A2-c-o-s-and-conventional-impression-technique
#10
Rinet Dauti, Barbara Cvikl, Alexander Franz, Uwe Yacine Schwarze, Bledar Lilaj, Tina Rybaczek, Andreas Moritz
BACKGROUND: Evaluation of the marginal fit of cemented zirconia copings manufactured after digital impression with Lava™ Chairside Oral Scanner in comparison to that of zirconia copings manufactured after conventional impressions with polyvinyl siloxane. METHODS: A prepared typodont tooth #36, was replicated 40 times with a vinyl silicone and precise model resin. The dies were randomly divided into two groups according to the impression taking technique. Digital impressions with Lava™ C...
December 8, 2016: BMC Oral Health
https://www.readbyqxmd.com/read/27930717/a-patient-specific-polylactic-acid-bolus-made-by-a-3d-printer-for-breast-cancer-radiation-therapy
#11
So-Yeon Park, Chang Heon Choi, Jong Min Park, MinSoo Chun, Ji Hye Han, Jung-In Kim
PURPOSE: The aim of this study was to assess the feasibility and advantages of a patient-specific breast bolus made using a 3D printer technique. METHODS: We used the anthropomorphic female phantom with breast attachments, which volumes are 200, 300, 400, 500 and 650 cc. We simulated the treatment for a right breast patient using parallel opposed tangential fields. Treatment plans were used to investigate the effect of unwanted air gaps under bolus on the dose distribution of the whole breast...
2016: PloS One
https://www.readbyqxmd.com/read/27930656/cross-sectional-associations-between-socio-demographic-factors-and-cognitive-performance-in-an-older-british-population-the-european-investigation-of-cancer-in-norfolk-epic-norfolk-study
#12
Shabina A Hayat, Robert Luben, Nichola Dalzell, Stephanie Moore, Serena Anuj, Fiona E Matthews, Nick Wareham, Carol Brayne, Kay-Tee Khaw
BACKGROUND: Cognition covers a range of abilities, such as memory, response time and language, with tests assessing either specific or generic aspects. However differences between measures may be observed within the same individuals. OBJECTIVE: To investigate the cross-sectional association of cognitive performance and socio-demographic factors using different assessment tools across a range of abilities in a British cohort study. METHODS: Participants of the European Prospective Investigation of Cancer (EPIC) in Norfolk Study, aged 48-92 years, underwent a cognitive assessment between 2006 and 2011 (piloted between 2004 and 2006) and were investigated over a different domains using a range of cognitive tests...
2016: PloS One
https://www.readbyqxmd.com/read/27930515/usefulness-of-the-maximum-rate-of-pressure-rise-in-the-central-and-peripheral-arteries-after-weaning-from-cardiopulmonary-bypass-in-pediatric-congenital-heart-surgery-a-retrospective-analysis
#13
Jung-Won Kim, Ji-Yeon Bang, Chun Soo Park, Mijeung Gwak, Won-Jung Shin, Gyu-Sam Hwang
The maximum rate of pressure rise (dP/dtmax) in radial artery has been proposed as a noninvasive surrogate of aortic dp/dtmax, reflecting left ventricular (LV) contractility in children. The aim of this study was to investigate relationship between aortic and radial dp/dtmax at weaning from cardiopulmonary bypass (CPB) and usefulness of these indices for estimating postoperative outcomes in pediatric congenital heart surgery.Aortic and radial arterial pressure waveforms were analyzed simultaneously during weaning from CPB in 29 congenital heart surgery...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930444/a-mysterious-role-of-arginine-vasopressin-levels-in-m%C3%A3-ni%C3%A3-re-s-disease-meta-analysis-of-clinical-studies
#14
Jing Wu, Jie Zhou, Lu Dong, Wenjing Fan, Jinyu Zhang, Caiqin Wu
OBJECTIVE: There are contradicting claims that patients with Ménière's disease (MD) have elevated levels of arginine vasopressin (AVP). The results of published studies regarding the difference of AVP level between MD patients and non-MD control subjects are inconsistent. We propose that the discrepancy of AVP levels during different MD phases may be a potential reason. Thus, we conducted a meta-analysis to analyze the precise estimate of this hypothesis. DATA SOURCES: PubMed, Medline, and Cochrane databases from the earliest publication, up until September 2016; references from meta-analyses and related review articles...
December 7, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27929492/treatment-planning-for-metals-using-an-extended-ct-number-scale
#15
John P Mullins, Michael P Grams, Michael G Herman, Debra H Brinkmann, John A Antolak
Metal implants which saturate the CT number scale may require dosimetrist and physicist involvement to manually contour and assign an appropriate value to the metal for accurate dose calculation. This study investigated dose calculation based directly on extended CT scale images for different metals and geometries. The aim was to evaluate extended CT accuracy as a suitable alternative to standard CT methods in the presence of high-Z materials and artifacts, despite the reduced HU resolution of extended CT. Gafchromic film measurements were made for comparison to calculated doses...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929338/-still-feeling-healthy-after-all-these-years-the-paradox-of-subjective-stability-versus-objective-decline-in-very-old-adults-health-and-functioning-across-five-years
#16
Markus Wettstein, Oliver K Schilling, Hans-Werner Wahl
Indicators of objective functioning, such as everyday competence or sensory and sensorimotor functions, typically show pronounced declines in very old age. However, less is known about how very old adults perceive their abilities across multiple domains of health and functioning and to what extent changes in perceived functioning mirror changes in objective functioning. We compared changes in perceived versus objective health and functioning indicators among very old adults (n = 124; baseline age between 87 and 97 years, M = 90...
December 2016: Psychology and Aging
https://www.readbyqxmd.com/read/27929317/informant-discrepancies-in-externalizing-and-internalizing-symptoms-and-adaptive-skills-of-high-functioning-children-with-autism-spectrum-disorder
#17
Christin A McDonald, Christopher Lopata, James P Donnelly, Marcus L Thomeer, Jonathan D Rodgers, Allyson K Jordan
Assessment of clinical symptoms requires information from multiple informants. Discrepancies between informants' ratings can have significant implications in school settings (e.g., access to services, treatment planning, progress monitoring). This study examined parent-teacher discrepancies for ratings of internalizing and externalizing symptoms, and adaptive skills of high-functioning children with autism spectrum disorder. A total of 236 Behavior Assessment System for Children-2nd Edition ratings of children with high-functioning children with autism spectrum disorder from 2 informant groups (parents and teachers) were analyzed...
December 2016: School Psychology Quarterly
https://www.readbyqxmd.com/read/27929316/assessing-understanding-and-supporting-students-with-autism-at-school-contemporary-science-practice-and-policy
#18
Janine P Stichter, T Chris Riley-Tillman, Shane R Jimerson
Over the past 3 decades, there has been an unprecedented increase in students identified as eligible for special education as a result of students meeting criteria for autism spectrum disorder (ASD). The increasing number of students with ASD in the schools presents significant challenges to teachers, school psychologists, and other school professionals working with this population. Although there is considerable research addressing assessment, identification, and support services for children with ASD, there is a need for further research focused on these topics within the school context...
December 2016: School Psychology Quarterly
https://www.readbyqxmd.com/read/27929122/coastal-barrier-stratigraphy-for-holocene-high-resolution-sea-level-reconstruction
#19
Susana Costas, Óscar Ferreira, Theocharis A Plomaritis, Eduardo Leorri
The uncertainties surrounding present and future sea-level rise have revived the debate around sea-level changes through the deglaciation and mid- to late Holocene, from which arises a need for high-quality reconstructions of regional sea level. Here, we explore the stratigraphy of a sandy barrier to identify the best sea-level indicators and provide a new sea-level reconstruction for the central Portuguese coast over the past 6.5 ka. The selected indicators represent morphological features extracted from coastal barrier stratigraphy, beach berm and dune-beach contact...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27928750/phytoextraction-of-arsenic-contaminated-soil-with-pteris-vittata-in-henan-province-china-comprehensive-evaluation-of-remediation-efficiency-correcting-for-atmospheric-depositions
#20
Mei Lei, Xiaoming Wan, Guanghui Guo, Junxing Yang, Tongbin Chen
Research on the appropriate method for evaluating phytoremediation efficiency is limited. A 2-year field experiment was conducted to investigate phytoremediation efficiency using the hyperaccumulator Pteris vittata on an arsenic (As)-contaminated site. The remediation efficiency was evaluated through the removal rate of As in soils and extraction rate of heavy metals in plants. After 2 years of remediation, the concentration of total As in soils decreased from 16.27 mg kg(-1) in 2012 to 14.58 mg kg(-1) in 2014...
December 7, 2016: Environmental Science and Pollution Research International
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