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"Real-time MRI"

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https://www.readbyqxmd.com/read/27871890/respiratory-dynamics-in-phonation-and-breathing-a-real-time-mri-study
#1
Louisa Traser, Ali Caglar Özen, Fabian Burk, Michael Burdumy, Michael Bock, Bernhard Richter, Matthias Echternach
The respiratory system is a central part of voice production, but for phonation neither the underlying functional relations between diaphragm (DPH) and rib cage (RC), nor differences to normal breathing are yet understood. This study aims to compare respiratory dynamics in phonation and breathing via dynamic MRI of the lung. Images of the breathing apparatus of 6 professional singers were captured in a 1.5T MRI system in supine position during vital capacity breathing and maximal long sustained phonation at 3 different pitches and loudness conditions...
November 18, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27842671/real-time-mri-of-the-temporomandibular-joint-at-15-frames-per-second-a-feasibility-study
#2
Sebastian Krohn, Nikolaus Gersdorff, Torsten Wassmann, Klaus-Dietmar Merboldt, Arun A Joseph, Ralf Buergers, Jens Frahm
The purpose of this study was to develop and evaluate a novel method for real-time MRI of TMJ function at high temporal resolution and with two different contrasts. Real-time MRI was based on undersampled radial fast low angle shot (FLASH) acquisitions with iterative image reconstruction by regularized nonlinear inversion. Real-time MRI movies with T1 contrast were obtained with use of a radiofrequency-spoiled FLASH sequence, while movies with T2/T1 contrast employed a gradient-refocused FLASH version. TMJ function was characterized in 40 randomly selected volunteers by sequential 20s acquisitions of both the right and left joint during voluntary opening and closing of the mouth (in a medial, central and lateral oblique sagittal section perpendicular to the long axis of the condylar head)...
December 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27814819/an-abbreviated-protocol-for-high-risk-screening-breast-mri-saves-time-and-resources
#3
Susan C Harvey, Phillip A Di Carlo, Bonmyong Lee, Eniola Obadina, Dorothy Sippo, Lisa Mullen
PURPOSE: To review the ability of an abbreviated, high-risk, screening, breast MRI protocol to detect cancer and save resources. METHODS: High-risk screening breast MR images were reviewed, from both an abbreviated protocol and a full diagnostic protocol. Differences in cancer detection, scanner utilization, interpretation times, and need for additional imaging were recorded in an integrated data form, and reviewed and compared. RESULTS: A total of 568 MRI cases were reviewed, with the abbreviated and full protocols...
November 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/27779127/towards-real-time-mri-guided-3d-localization-of-deforming-targets-for-non-invasive-cardiac-radiosurgery
#4
S Ipsen, O Blanck, N J Lowther, G P Liney, R Rai, F Bode, J Dunst, A Schweikard, P J Keall
Radiosurgery to the pulmonary vein antrum in the left atrium (LA) has recently been proposed for non-invasive treatment of atrial fibrillation (AF). Precise real-time target localization during treatment is necessary due to complex respiratory and cardiac motion and high radiation doses. To determine the 3D position of the LA for motion compensation during radiosurgery, a tracking method based on orthogonal real-time MRI planes was developed for AF treatments with an MRI-guided radiotherapy system. Four healthy volunteers underwent cardiac MRI of the LA...
November 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27770070/evaluation-of-dysphagia-by-novel-real-time-mri
#5
Arno Olthoff, Per-Ole Carstens, Shuo Zhang, Eva von Fintel, Tim Friede, Joachim Lotz, Jens Frahm, Jens Schmidt
OBJECTIVE: To assess safety and feasibility of real-time (RT) MRI for evaluation of dysphagia and to compare this technique to standard assessment by flexible endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VF) in a cohort of patients with inclusion body myositis (IBM). METHODS: Using RT-MRI, FEES, and VF, an unselected cohort of 20 patients with IBM was studied as index disease with a uniform dysphagia. Symptoms of IBM and dysphagia were explored by standardized tools including Swallowing-Related Quality of Life Questionnaire (SWAL-QoL), IBM Functional Rating Scale, Patient-Reported Functional Assessment, and Medical Research Council Scale...
November 15, 2016: Neurology
https://www.readbyqxmd.com/read/27690659/intracerebral-laser-interstitial-thermal-therapy-followed-by-tumor-resection-to-minimize-cerebral-edema
#6
Sindhura Pisipati, Kyle A Smith, Kushal Shah, Koji Ebersole, Roukoz B Chamoun, Paul J Camarata
OBJECTIVE Laser interstitial thermal therapy (LITT) is used in numerous neurosurgical applications including lesions that are difficult to resect. Its rising popularity can be attributed to its minimally invasive approach, improved accuracy with real-time MRI guidance and thermography, and enhanced control of the laser. One of its drawbacks is the possible development of significant edema, which contributes to extended hospital stays and often necessitates hyperosmolar or steroid therapy. Here, the authors discuss the use of minimally invasive craniotomy to resect tissue ablated with LITT in attempt to minimize cerebral edema...
October 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27687293/real-time-mri-of-swallowing-intraoral-pressure-reduction-supports-larynx-elevation
#7
Arno Olthoff, Arun A Joseph, Matthias Weidenmüller, Blake Riley, Jens Frahm
The reduction in intraoral pressure during swallowing has previously been linked to bolus transport, although no such relation has yet been proven. The purpose of this work was to evaluate the time course of intraoral pressure during swallowing using simultaneous real-time magnetic resonance imaging (MRI) and dynamic pressure recordings. Real-time MRI based on highly undersampled radial fast low-angle shot (FLASH) and regularized nonlinear inverse reconstruction was performed at 3 T using a standard head coil and a mid-sagittal section covering the entire oral cavity...
September 30, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27675260/reducing-magnetic-field-dosimetric-impact-on-real-time-mri-guided-radiation-therapy-patients-by-reversing-the-mri-magnetic-field-inside-patients-halfway-through-fractionated-radiation-therapy-delivery
#8
S M Zhou
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27631028/real-time-magnetic-resonance-imaging-guidance-improves-the-diagnostic-yield-of-endomyocardial-biopsy
#9
Toby Rogers, Kanishka Ratnayaka, Parag Karmarkar, Adrienne E Campbell-Washburn, William H Schenke, Jonathan R Mazal, Ozgur Kocaturk, Anthony Z Faranesh, Robert J Lederman
BACKGROUND: Diagnostic yield of endomyocardial biopsy is low, particularly in disease that affects the myocardium in a non-uniform distribution. We hypothesized that real-time MRI guidance could improve the yield through targeted biopsy of focal myocardial pathology. METHODS: An animal model of focal myocardial pathology was created by infusing 3mL of fluorescent microspheres (NuFlow Hydrocoat, 15μm diameter, 5 million spheres/mL) followed by 2mL of 100% ethanol to a branch coronary artery...
August 2016: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/27618834/real-time-mri-for-precise-and-predictable-intra-arterial-stem-cell-delivery-to-the-central-nervous-system
#10
Piotr Walczak, Joanna Wojtkiewicz, Adam Nowakowski, Aleksandra Habich, Piotr Holak, Jiadi Xu, Zbigniew Adamiak, Moussa Chehade, Monica S Pearl, Philippe Gailloud, Barbara Lukomska, Wojciech Maksymowicz, Jeff Wm Bulte, Miroslaw Janowski
Stem cell therapy for neurological disorders reached a pivotal point when the efficacy of several cell types was demonstrated in small animal models. Translation of stem cell therapy is contingent upon overcoming the challenge of effective cell delivery to the human brain, which has a volume ∼1000 times larger than that of the mouse. Intra-arterial injection can achieve a broad, global, but also on-demand spatially targeted biodistribution; however, its utility has been limited by unpredictable cell destination and homing as dictated by the vascular territory, as well as by safety concerns...
September 12, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27618633/predictive-parameters-identifying-men-eligible-for-a-sole-mri-ultrasound-fusion-guided-targeted-biopsy-without-an-additional-systematic-biopsy
#11
Karsten Günzel, Matthias Haas, Andreas Maxeiner, Carsten Stephan, John Buckendahl, Patrick Asbach, Kurt Miller, Carsten Kempkensteffen, Hannes Cash
OBJECTIVE: Evaluating the predictive factors that enable identifying men in which a sole MRI/ultrasound (MRI/US) fusion-guided targeted biopsy (TB) detects the maximal prostate cancer (PCa) risk group. PATIENTS AND METHODS: Retrospective analysis of 251 consecutive patients who received a sensor-based, real-time MRI/US TB in combination with a 10-core systematic biopsy (SB) between August 2013 and July 2015. Univariate and multivariate binary regression analyses were performed to evaluate the predictors for equal/superior detection of the PCa risk group by TB compared to SB...
September 13, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27597889/open-source-small-animal-magnetic-resonance-guided-focused-ultrasound-system
#12
Megan E Poorman, Vandiver L Chaplin, Ken Wilkens, Mary D Dockery, Todd D Giorgio, William A Grissom, Charles F Caskey
BACKGROUND: MR-guided focused ultrasound or high-intensity focused ultrasound (MRgFUS/MRgHIFU) is a non-invasive therapeutic modality with many potential applications in areas such as cancer therapy, drug delivery, and blood-brain barrier opening. However, the large financial costs involved in developing preclinical MRgFUS systems represent a barrier to research groups interested in developing new techniques and applications. We aim to mitigate these challenges by detailing a validated, open-source preclinical MRgFUS system capable of delivering thermal and mechanical FUS in a quantifiable and repeatable manner under real-time MRI guidance...
2016: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/27587958/real-time-mri-navigated-ultrasound-for-preoperative-tumor-evaluation-in-breast-cancer-patients-technique-and-clinical-implementation
#13
Ah Young Park, Bo Kyoung Seo
Real-time magnetic resonance imaging (MRI) navigated ultrasound is an image fusion technique to display the results of both MRI and ultrasonography on the same monitor. This system is a promising technique to improve lesion detection and analysis, to maximize advantages of each imaging modality, and to compensate the disadvantages of both MRI and ultrasound. In evaluating breast cancer stage preoperatively, MRI and ultrasound are the most representative imaging modalities. However, sometimes difficulties arise in interpreting and correlating the radiological features between these two different modalities...
September 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/27487907/cnr-considerations-for-rapid-real-time-mri-tumor-tracking-in-radiotherapy-hybrid-devices-effects-of-b0-field-strength
#14
K Wachowicz, N De Zanche, E Yip, V Volotovskyy, B G Fallone
PURPOSE: This work examines the subject of contrast-to-noise ratio (CNR), specifically between tumor and tissue background, and its dependence on the MRI field strength, B0. This examination is motivated by the recent interest and developments in MRI/radiotherapy hybrids where real-time imaging can be used to guide treatment beams. The ability to distinguish a tumor from background tissue is of primary importance in this field, and this work seeks to elucidate the complex relationship between the CNR and B0 that is too often assumed to be purely linear...
August 2016: Medical Physics
https://www.readbyqxmd.com/read/27417271/water-and-fat-separation-in-real-time-mri-of-joint-movement-with-phase-sensitive-bssfp
#15
Valentina Mazzoli, Aart J Nederveen, Jos Oudeman, Andre Sprengers, Klaas Nicolay, Gustav J Strijkers, Nico Verdonschot
PURPOSE: To introduce a method for obtaining fat-suppressed images in real-time MRI of moving joints at 3 Tesla (T) using a bSSFP sequence with phase detection to enhance visualization of soft tissue structures during motion. METHODS: The wrist and knee of nine volunteers were imaged with a real-time bSSFP sequence while performing dynamic tasks. For appropriate choice of sequence timing parameters, water and fat pixels showed an out-of-phase behavior, which was exploited to reconstruct water and fat images...
July 15, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27396404/glioma-targeted-superparamagnetic-iron-oxide-nanoparticles-as-drug-carrying-vehicles-for-theranostic-effects
#16
He-Lin Xu, Kai-Li Mao, Yin-Ping Huang, Jing-Jing Yang, Jie Xu, Pian-Pian Chen, Zi-Liang Fan, Shuang Zou, Zheng-Zheng Gao, Jia-Yu Yin, Jian Xiao, Cui-Tao Lu, Bao-Lin Zhang, Ying-Zheng Zhao
Multifunctional nanoparticles capable of the specific delivery of therapeutics to diseased cells and the real-time imaging of these sites have the potential to improve cancer treatment through personalized therapy. In this study, we have proposed a multifunctional nanoparticle that integrate magnetic targeting, drug-carrier functionality and real-time MRI imaging capabilities in one platform for the theranostic treatment of tumors. The multifunctional nanoparticle was designed with a superparamagnetic iron oxide core and a multifunctional shell composed of PEG/PEI/polysorbate 80 (Ps 80) and was used to encapsulate DOX...
August 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27246950/robotic-assisted-real-time-mri-guided-tavr-from-system-deployment-to-in-vivo-experiment-in-swine-model
#17
Joshua L Chan, Dumitru Mazilu, Justin G Miller, Timothy Hunt, Keith A Horvath, Ming Li
PURPOSE: Real-time magnetic resonance imaging (rtMRI) guidance provides significant advantages during transcatheter aortic valve replacement (TAVR) as it provides superior real-time visualization and accurate device delivery tracking. However, performing a TAVR within an MRI scanner remains difficult due to a constrained procedural environment. To address these concerns, a magnetic resonance (MR)-compatible robotic system to assist in TAVR deployments was developed. This study evaluates the technical design and interface considerations of an MR-compatible robotic-assisted TAVR system with the purpose of demonstrating that such a system can be developed and executed safely and precisely in a preclinical model...
October 2016: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/27096935/morphometric-differences-of-vocal-tract-articulators-in-different-loudness-conditions-in-singing
#18
Matthias Echternach, Fabian Burk, Michael Burdumy, Louisa Traser, Bernhard Richter
INTRODUCTION: Dynamic MRI analysis of phonation has gathered interest in voice and speech physiology. However, there are limited data addressing the extent to which articulation is dependent on loudness. MATERIAL AND METHODS: 12 professional singer subjects of different voice classifications were analysed concerning the vocal tract profiles recorded with dynamic real-time MRI with 25fps in different pitch and loudness conditions. The subjects were asked to sing ascending scales on the vowel /a/ in three loudness conditions (comfortable=mf, very soft=pp, very loud=ff, respectively)...
2016: PloS One
https://www.readbyqxmd.com/read/27085581/magnetic-resonance-imaging-guided-transcatheter-cavopulmonary-shunt
#19
Kanishka Ratnayaka, Toby Rogers, William H Schenke, Jonathan R Mazal, Marcus Y Chen, Merdim Sonmez, Michael S Hansen, Ozgur Kocaturk, Anthony Z Faranesh, Robert J Lederman
OBJECTIVES: The aim of this study was to test the hypothesis that real-time magnetic resonance imaging (MRI) would enable closed-chest percutaneous cavopulmonary anastomosis and shunt by facilitating needle guidance along a curvilinear trajectory, around critical structures, and between a superior vena cava "donor" vessel and a pulmonary artery "target." BACKGROUND: Children with single-ventricle physiology require multiple open heart operations for palliation, including sternotomies and cardiopulmonary bypass...
May 9, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27079944/image-denoising-for-real-time-mri
#20
Jakob Klosowski, Jens Frahm
PURPOSE: To develop an image noise filter suitable for MRI in real time (acquisition and display), which preserves small isolated details and efficiently removes background noise without introducing blur, smearing, or patch artifacts. THEORY AND METHODS: The proposed method extends the nonlocal means algorithm to adapt the influence of the original pixel value according to a simple measure for patch regularity. Detail preservation is improved by a compactly supported weighting kernel that closely approximates the commonly used exponential weight, while an oracle step ensures efficient background noise removal...
April 15, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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