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https://www.readbyqxmd.com/read/28918316/mr-guided-joint-reconstruction-of-activity-and-attenuation-in-brain-pet-mr
#1
Abolfazl Mehranian, Habib Zaidi, Andrew J Reader
With the advent of time-of-flight (TOF) PET scanners, joint maximum-likelihood reconstruction of activity and attenuation (MLAA) maps has recently regained attention for the estimation of PET attenuation maps from emission data. However, the estimated attenuation and activity maps are scaled by unknown scaling factors. We recently demonstrated that in hybrid PET-MR, the scaling issue of this algorithm can be effectively addressed by imposing MR spatial constraints on the estimation of attenuation maps using a penalized MLAA (P-MLAA(+)) algorithm...
September 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28917283/mri-guided-laser-interstitial-thermal-therapy-for-epilepsy
#2
REVIEW
Robert Y North, Jeffrey S Raskin, Daniel J Curry
MRI-guided laser interstitial thermal therapy for epilepsy (LITT-E) has become an established, minimally invasive alternative to traditional epilepsy surgery. LITT-E is particularly valuable in cases in which open surgery poses unacceptably high morbidity or patient preference precludes craniotomy. Here we present a focused review of technical details and application of LITT to both focal and generalized epilepsy.
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28917282/interventional-mri-guided-deep-brain-stimulation-lead-implantation
#3
REVIEW
Philip S Lee, Robert Mark Richardson
Current knowledge of the functional anatomy of the subthalamic nucleus and globus pallidus, discovered through microelectrode recording and postoperative imaging, justifies purely anatomic targeting for deep brain stimulation (DBS). Interventional MRI (iMRI)-DBS is more anatomically accurate than traditional awake procedures and has similar clinical outcomes without increased risk or increased operative times. iMRI lead implantation allows patients to receive DBS therapy who cannot tolerate or do not agree to undergo an awake procedure...
October 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/28906083/are-in-house-diagnostic-mr-physicists-necessary-for-clinical-implementation-of-mri-guided-radiotherapy
#4
EDITORIAL
Minsong Cao, Kyle R Padgett, Yi Rong
No abstract text is available yet for this article.
September 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28885120/threshold-of-the-extent-of-resection-for-who-grade-iii-gliomas-retrospective-volumetric-analysis-of-122-cases-using-intraoperative-mri
#5
Yu Fujii, Yoshihiro Muragaki, Takashi Maruyama, Masayuki Nitta, Taiichi Saito, Soko Ikuta, Hiroshi Iseki, Kazuhiro Hongo, Takakazu Kawamata
OBJECTIVE WHO Grade III gliomas are relatively rare and treated with multiple modalities such as surgery, chemotherapy, and radiotherapy. The impact of the extent of resection (EOR) on improving survival in patients with this tumor type is unclear. Moreover, because of the heterogeneous radiological appearance of Grade III gliomas, the MRI sequence that best correlates with tumor volume is unknown. In the present retrospective study, the authors evaluated the prognostic significance of EOR. METHODS Clinical and radiological data from 122 patients with newly diagnosed WHO Grade III gliomas who had undergone intraoperative MRI-guided resection at a single institution between March 2000 and December 2011 were analyzed retrospectively...
September 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28871396/retrospective-comparison-of-direct-in-bore-magnetic-resonance-imaging-mri-guided-biopsy-and-fusion-guided-biopsy-in-patients-with-mri-lesions-which-are-likely-or-highly-likely-to-be-clinically-significant-prostate-cancer
#6
Wulphert Venderink, Marloes van der Leest, Annemarijke van Luijtelaar, Wendy J M van de Ven, Jurgen J Fütterer, J P Michiel Sedelaar, Henkjan J Huisman
PURPOSE: To compare clinically significant prostate cancer (csPCa) detection rates between magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion-guided prostate biopsy (FGB) and direct in-bore MRI-guided biopsy (MRGB). METHODS: We performed a comparison of csPCa detection rates between FGB and MRGB. Included patients had (1) at least one prior negative TRUS biopsy; (2) a Prostate Imaging Reporting and Data System (PI-RADS) 4 or 5 lesion and (3) a lesion size of ≥8 mm measured in at least one direction...
September 4, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28867617/total-reference-air-kerma-can-accurately-predict-isodose-surface-volumes-in-cervix-cancer-brachytherapy-a-multicenter-study
#7
Karen S Nkiwane, Else Andersen, Jerome Champoudry, Astrid de Leeuw, Jamema Swamidas, Jacob Lindegaard, Richard Pötter, Christian Kirisits, Kari Tanderup
PURPOSE: To demonstrate that V60 Gy, V75 Gy, and V85 Gy isodose surface volumes can be accurately estimated from total reference air kerma (TRAK) in cervix cancer MRI-guided brachytherapy (BT). METHODS AND MATERIALS: 60 Gy, 75 Gy, and 85 Gy isodose surface volumes levels were obtained from treatment planning systems (VTPS) for 239 EMBRACE study patients from five institutions treated with various dose rates, fractionation schedules and applicators. An equation for estimating VTPS from TRAK was derived...
August 31, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28866023/where-do-trus-and-mri-guided-biopsies-miss-significant-prostate-cancer
#8
Lars Boesen, Nis Nørgaard, Vibeke Løgager, Ingegerd Balslev, Henrik S Thomsen
OBJECTIVE: To identify the location of missed sPCa lesions by transrectal ultrasound-guided (TRUSbx) and multiparametric MRI-guided biopsies (mpMRIbx) in men undergoing repeat biopsies. METHODS: 289 men with prior negative TRUSbx underwent mpMRI. The location of any suspicious lesion was registered and scored using PIRADS v1 classification according to the likelihood of being sPCa. All patients underwent repeat (re-)TRUSbx and targeted mpMRIbx (image fusion) of any suspicious lesion...
August 30, 2017: Urology
https://www.readbyqxmd.com/read/28844600/prostate-specific-antigen-parameters-and-prostate-health-index-enhance-prostate-cancer-prediction-with-the-in-bore-3-t-mri-guided-transrectal-targeted-prostate-biopsy-after-negative-12-core-biopsy
#9
Alexander Friedl, Kathrin Stangl, Wilhelm Bauer, Danijel Kivaranovic, Jenifer Schneeweiss, Martin Susani, Stephan Hruby, Lukas Lusuardi, Fritz Lomoschitz, Edith Eisenhuber-Stadler, Wolfgang Schima, Clemens Brössner
Objectives To assess prostate cancer (PCa) detection and prediction by combining the in-bore MRI-guided transrectal targeted prostate biopsy (MRGB) with prostate-specific antigen (PSA) parameters and the prostate health index (PHI) in case of negative 12-core standard biopsy (SB). Methods A total of 112 males (2014-2016) underwent 3.0T multi-parametric MRI (mpMRI) and subsequent MRGB of Prostate Imaging Reporting and Data System (PI-RADS) lesions 3-5. Ancillary PSA parameters (PSA ratio [%fPSA], PSA density [PSAD]) and the PHI and PHI density (PHID) were recorded...
August 24, 2017: Urology
https://www.readbyqxmd.com/read/28842228/microelectrode-recording-guided-versus-intraoperative-mri-guided-in-stn-deep-brain-stimulation-surgery-for-parkinson-s-disease-a-one-year-follow-up-study
#10
Xuemeng Liu, Jibo Zhang, Kai Fu, Rui Gong, Jincao Chen, Jie Zhang
Microelectrode recording (MER) and Intraoperative MRI (iMRI) have been used in DBS surgery for Parkinson's disease (PD), but comparative methodology is as yet lacking. Therefore, we compared the one-year follow-up outcomes of MER guided and iMRI guided STN-DBS surgery in PD patients. METHOD: We conducted a review comparing PD patients who underwent MER guided (n=76, group A) and iMRI guided STN-DBS surgery (n=61, group B ) in our institution. Pre- and postoperative assessments included UPDRS-III score, PDQ-39, MMSE, LEDDs and MR images...
August 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28835335/the-positive-outcome-of-mri-guided-vacuum-assisted-core-needle-breast-biopsies-is-not-influenced-by-a-prior-negative-targeted-second-look-ultrasound
#11
Romuald Ferré, Shaza AlSharif, Ann Aldis, Benoît G Mesurolle
PURPOSE: The study sought to investigate the outcome of breast magnetic resonance-guided biopsies as a function of the indication for magnetic resonance imaging (MRI), the MRI features of the lesions, and the performance or not of a targeted second-look ultrasound (SLUS) prior breast MRI-guided biopsy. METHODS: We identified 158 women with MRI-detected breast lesions scheduled for MRI-guided biopsy (2007-2013). Patient demographics, performance of targeted SLUS, imaging characteristics, and subsequent pathology results were reviewed...
August 21, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28831732/erratum-to-%C3%A2-an-mr-conditional-high-torque-pneumatic-stepper-motor-for-mri-guided-and-robot-assisted-intervention
#12
Yue Chen, Ka-Wai Kwok, Zion Tsz Ho Tse
No abstract text is available yet for this article.
August 22, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28830847/lesion-characteristics-histopathologic-results-and-follow-up-of-breast-lesions-after-mri-guided-biopsy
#13
Füsun Taşkın, Aykut Soyder, Ahmet Tanyeri, Veli Süha Öztürk, Alparslan Ünsal
PURPOSE: We aimed to assess the effectiveness of magnetic resonance imaging (MRI)-guided vacuum assisted breast biopsy (VABB), evaluate and compare the characteristics and histopathologic findings of lesions and overview the follow-up results of benign lesions. METHODS: MRI findings and histopathologic results of breast lesions biopsied by MRI-guided VABB between 2013 and 2016 were retrospectively analyzed. MRI findings closely related with malignancy were investigated in particular...
August 23, 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28819458/focused-ultrasound-hyperthermia-mediated-drug-delivery-using-thermosensitive-liposomes-and-visualized-with-in-vivo-two-photon-microscopy
#14
Marc A Santos, David E Goertz, Kullervo Hynynen
The future of nanomedicines in oncology requires leveraging more than just the passive drug accumulation in tumors through the enhanced permeability and retention effect. Promising results combining mild hyperthermia (HT) with lyso-thermosensitive liposomal doxorubicin (LTSL-DOX) has led to improved drug delivery and potent antitumor effects in pre-clinical studies. The ultimate patient benefit from these treatments can only be realized when robust methods of HT can be achieved clinically. One of the most promising methods of non-invasive HT is the use of focused ultrasound (FUS) with MRI thermometry for anatomical targeting and feedback...
2017: Theranostics
https://www.readbyqxmd.com/read/28782985/pathologic-findings-of-breast-lesions-detected-on-magnetic-resonance-imaging
#15
Seema B Jabbar, Beverly Lynch, Stephen Seiler, Helena Hwang, Sunati Sahoo
CONTEXT: - Breast magnetic resonance imaging (MRI) is now used routinely for high-risk screening and in the evaluation of the extent of disease in newly diagnosed breast cancer patients. Morphologic characteristics and the kinetic pattern largely determine how suspicious a breast lesion is on MRI. Because of its high sensitivity, MRI identifies a large number of suspicious lesions. However, the low to moderate specificity and the additional cost have raised questions regarding its frequent use...
August 7, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28771144/effect-of-intra-fraction-motion-on-the-accumulated-dose-for-free-breathing-mr-guided-stereotactic-body-radiation-therapy-of-renal-cell-carcinoma
#16
Bjorn Stemkens, Markus Glitzner, Charis Kontaxis, Baudouin Denis de Senneville, Fieke M Prins, Sjoerd P M Crijns, Linda G W Kerkmeijer, Jan J W Lagendijk, Cornelis A T van den Berg, Rob H N Tijssen
Stereotactic body radiation therapy (SBRT) has shown great promise in increasing local control rates for renal-cell carcinoma (RCC). Characterized by steep dose gradients and high fraction doses, these hypo-fractionated treatments are, however, prone to dosimetric errors as a result of variations in intra-fraction respiratory-induced motion, such as drifts and amplitude alterations. This may lead to significant variations in the deposited dose. This study aims to develop a method for calculating the accumulated dose for MRI-guided SBRT of RCC in the presence of intra-fraction respiratory variations and determine the effect of such variations on the deposited dose...
September 1, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28764881/dosimetric-impact-of-intrafraction-changes-in-mr-guided-high-dose-rate-hdr-brachytherapy-for-prostate-cancer
#17
Alexandra Rink, Jette Borg, Anna Simeonov, Gerald O'Leary, Joelle Helou, Cynthia Ménard, Peter Chung, David A Jaffray, Alejandro Berlin
PURPOSE: To assess changes in implant and treatment volumes through the course of a prostate high-dose-rate brachytherapy procedure and their impact on plan quality metrics. METHODS AND MATERIALS: Sixteen MRI-guided high-dose-rate procedures included a post-treatment MR (ptMR) immediately after treatment delivery (135 min between MR scans). Target and organs at risk (OARs) were contoured, and catheters were reconstructed. The delivered treatment plan was applied to the ptMR image set...
July 29, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28761393/a-combined-intravascular-mri-endoscope-and-intravascular-ultrasound-ivus-transducer-for-high-resolution-image-guided-ablation
#18
Xiaoyang Liu, Nicholas Ellens, Emery Williams, Everette Clif Burdette, Parag Karmarkar, Paul Bottomley
An intravascular MRI (IMRI) loopless antenna is combined for the first time with an intravascular water-cooled ultrasound ablation transducer as a possible tool for providing high-resolution MRI-guided ablations of pathological tissue via intravascular access. High resolution anatomical MRI, and real-time MRI thermometry were used to monitor ablation delivery in phantoms and tissue specimens. Results show that IMRI can guide IVUS-mediated directional ablation with minimal image artifacts. This permits the monitoring of thermal dose and therapy titration while minimizing potential thermal damage to the vessel wall...
April 2017: Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition
https://www.readbyqxmd.com/read/28757404/intermediate-dose-volume-parameters-and-the-development-of-late-rectal-toxicity-after-mri-guided-brachytherapy-for-locally-advanced-cervix-cancer
#19
Reem Ujaimi, Michael Milosevic, Anthony Fyles, Akbar Beiki-Ardakani, Marco Carlone, Haiyan Jiang, Patricia Lindsay, Jason Xie, Rachel Gerber, Jennifer Croke, Julia Skliarenko, Wilfred Levin, Kathy Han
PURPOSE: The dose delivered to the most exposed 2 cm(3) [Formula: see text] of the rectum and bladder is predictive of late rectal and bladder toxicity in cervix cancer patients. We investigated the predictive value of intermediate doses to the rectum and bladder for late rectal/bladder toxicity after MRI-guided brachytherapy for patients with locally advanced cervix cancer. METHODS AND MATERIALS: Toxicity was prospectively graded using Common Toxicity Criteria for Adverse Events v4...
July 27, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28754486/what-is-the-yield-of-breast-mri-in-the-assessment-of-palpable-breast-findings
#20
Y Amitai, T S Menes, I Weinstein, A Filyavich, I Yakobson, O Golan
AIM: To examine the contribution of magnetic resonance imaging (MRI) to characterise palpable breast masses after conventional imaging was found to be non-contributory. MATERIALS AND METHODS: The breast MRI database was reviewed for studies performed between January 2010 and December 2015 for the clinical indication of palpable breast finding with negative standard imaging. Medical files were reviewed for demographic data, clinical information, radiology, and pathology reports...
July 25, 2017: Clinical Radiology
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