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https://www.readbyqxmd.com/read/27911756/activation-of-group-ii-metabotropic-glutamate-receptors-promotes-ltp-induction-at-schaffer-collateral-ca1-pyramidal-cell-synapses-by-priming-nmda-receptors
#1
Nadia Rosenberg, Urs Gerber, Jeanne Ster
: It is well established that selective activation of group I metabotropic glutamate (mGlu) receptors induces LTD of synaptic transmission at Schaffer collateral-CA1 synapses. In contrast, application of 1S,3R-ACPD, a mixed agonist at group I and group II mGlu receptors, induces LTP. Using whole-cell recordings from CA1 pyramidal cells and field recordings in the hippocampal CA1 region, we investigated the specific contribution of group II mGlu receptors to synaptic plasticity at Schaffer collateral-CA1 synapses in acute slices of adult mice...
November 9, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27906664/pearls-oy-sters-plasma-cell-meningitis-an-uncommon-complication-of-multiple-myeloma
#2
Neville Jadeja, Krishna Nalleballe, Jerome Graber
No abstract text is available yet for this article.
November 15, 2016: Neurology
https://www.readbyqxmd.com/read/27868244/ddw-2016-review-advances-in-therapeutic-upper-gastrointestinal-endoscopy
#3
REVIEW
Shannon Melissa Chan, Baldwin Yeung, Philip Wai Yan Chiu
This editorial provides a review of the lectures and abstracts presented at Digestive Disease Week 2016 in San Diego on advances in therapeutic upper gastrointestinal procedures. There were a significant number of reports on expanded indications for endoscopic submucosal dissection (ESD) of early gastric cancers, advanced endoscopic techniques for resection including submucosal tunnel endoscopic resection (STER) and endoscopic full thickness resection (EFTR), per oral endoscopic myotomy (POEM), and novel endoscopic techniques including antireflux mucosectomy (ARMS) as well as endoscopic suturing...
November 21, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27864722/comparison-between-submucosal-tunneling-endoscopic-resection-and-endoscopic-full-thickness-resection-for-gastric-stromal-tumors-originating-from-the-muscularis-propria-layer
#4
Yuyong Tan, Xiaoyu Tang, Ting Guo, Dongzi Peng, Yao Tang, Tianying Duan, Xuehong Wang, Liang Lv, Jirong Huo, Deliang Liu
BACKGROUND: Both submucosal tunneling endoscopic resection (STER) and endoscopic full-thickness resection (EFTR) are effective method for treating gastric gastrointestinal stromal tumors (GISTs); however, little is known about the comparison between STER and EFTR. The aim of the study was to compare the safety and efficacy of STER and EFTR for treating gastric GIST. METHODS: We retrospectively collected the clinical data about patients with gastric GISTs who received STER or EFTR at our hospital from April 2011 to June 2016...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27855187/characterization-of-a-vrag-mutant-in-a-genetically-stable-staphylococcus-aureus-small-colony-variant-and-preliminary-assessment-for-use-as-a-live-attenuated-vaccine-against-intrammamary-infections
#5
Julie Côté-Gravel, Eric Brouillette, Nataša Obradović, Céline Ster, Brian G Talbot, François Malouin
Staphylococcus aureus is a leading cause of bovine intramammary infections (IMIs) that can evolve into difficult-to-treat chronic mastitis. To date, no vaccine formulation has shown high protective efficacy against S. aureus IMI, partly because this bacterium can efficiently evade the immune system. For instance, S. aureus small colony variants (SCVs) have intracellular abilities and can persist without producing invasive infections. As a first step towards the development of a live vaccine, this study describes the elaboration of a novel attenuated mutant of S...
2016: PloS One
https://www.readbyqxmd.com/read/27821572/pearls-oy-sters-visual-agnosia-an-overlooked-cortical-sign
#6
Bruno Bergmans, Olivier Deryck, Rose Bruffaerts
No abstract text is available yet for this article.
November 8, 2016: Neurology
https://www.readbyqxmd.com/read/27765828/pearls-oy-sters-an-unusual-cause-of-hypokalemic-paralysis
#7
Ritu Shree, Manoj Kumar Goyal, Rajveer Singh, Manish Modi, Vivek Lal, Nandita Kakkar
No abstract text is available yet for this article.
October 11, 2016: Neurology
https://www.readbyqxmd.com/read/27747286/an-innovative-ex-vivo-porcine-upper-gastrointestinal-model-for-submucosal-tunnelling-endoscopic-resection-ster
#8
Baldwin Yeung, Philip Chiu, Anthony Teoh, Linfu Zheng, Shannon Chan, Kelvin Lam, Raymond Tang, Enders K W Ng
Background and study aims: Submucosal tunnelling endoscopic resection (STER) is a novel endoscopic technique to remove submucosal tumour (SMT). We propose a novel, low cost simulator for training of techniques for STER. Patients and methods: The model consisted of an ex-planted porcine oesophagus, stomach and duodenum with marbles embedded surgically in the submucosal plane. Two expert endoscopists with experience in submucosal tunnelling and 5 board-certified endoscopists with no experience in submucosal tunnelling were recruited...
October 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27738443/self-care-for-common-colds-by-primary-care-patients-a-european-multicenter-survey-on-the-prevalence-and-patterns-of-practices-the-coco-study
#9
Anika Thielmann, Biljana Gerasimovska-Kitanovska, Krzysztof Buczkowski, Tuomas H Koskela, Vildan Mevsim, Slawomir Czachowski, Ferdinando Petrazzuoli, Marija Petek-Šter, Heidrun Lingner, Robert D Hoffman, Selda Tekiner, Juliette Chambe, Tamer Edirne, Kathryn Hoffmann, Enzo Pirrotta, Ayşegül Uludağ, Hülya Yikilkan, Sanda Kreitmayer Pestic, Andrzej Zielinski, Clara Guede Fernández, Birgitta Weltermann
Background. Patients use self-care to relieve symptoms of common colds, yet little is known about the prevalence and patterns across Europe. Methods/Design. In a cross-sectional study 27 primary care practices from 14 countries distributed 120 questionnaires to consecutive patients (≥18 years, any reason for consultation). A 27-item questionnaire asked for patients' self-care for their last common cold. Results. 3,074 patients from 27 European sites participated. Their mean age was 46.7 years, and 62.5% were females...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27707004/n-tuple-topological-geometric-cutoffs-for-3d-n-linear-algebraic-molecular-codifications-variability-linear-independence-and-qsar-analysis
#10
C R García-Jacas, Y Marrero-Ponce, S J Barigye, T Hernández-Ortega, L Cabrera-Leyva, A Fernández-Castillo
Novel N-tuple topological/geometric cutoffs to consider specific inter-atomic relations in the QuBiLS-MIDAS framework are introduced in this manuscript. These molecular cutoffs permit the taking into account of relations between more than two atoms by using (dis-)similarity multi-metrics and the concepts related with topological and Euclidean-geometric distances. To this end, the kth two-, three- and four-tuple topological and geometric neighbourhood quotient (NQ) total (or local-fragment) spatial-(dis)similarity matrices are defined, to represent 3D information corresponding to the relations between two, three and four atoms of the molecular structures that satisfy certain cutoff criteria...
December 2016: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/27701926/twenty-five-years-of-the-international-bled-course-for-teachers-of-family-medicine-in-europe-glancing-back-and-looking-forward
#11
Zalika Klemenc-Ketis, Igor Svab, Marija Petek-Ster, Mateja Bulc, Josephine Buchanan, Henry Finnegan, Jaime Correia de Sousa, John Yaphe
The international Bled course for teacher training has played a central role in faculty development in family medicine for the past 25 years. The course was originally designed to promote faculty development for family medicine teachers in the new academic discipline of family medicine in Slovenia in 1990 and to introduce new topics into the family medicine curriculum. In this background paper, we perform a SCOT analysis (strengths, challenges, opportunities, and threats) of the current course, evaluating participant feedback and reviewing past topics and their impact on local and international teaching programmes...
October 5, 2016: European Journal of General Practice
https://www.readbyqxmd.com/read/27672168/pearls-oy-sters-tacrolimus-neurotoxicity-presenting-as-an-isolated-brainstem-lesion
#12
Gregory Y Chang, Altaf Saadi, Jeremy D Schmahmann
No abstract text is available yet for this article.
September 27, 2016: Neurology
https://www.readbyqxmd.com/read/27671744/submucosal-tunneling-endoscopic-resection-using-methylene-blue-guidance-for-cardial-subepithelial-tumors-originating-from-the-muscularis-propria-layer
#13
Xin-Li Mao, Li-Ping Ye, Hai-Hong Zheng, Xian-Bin Zhou, Lin-Hong Zhu, Yu Zhang
Submucosal tunneling endoscopic resection (STER) of subepithelial tumors (SETs) originating from the muscularis propria (MP) layer in the cardia is rarely performed due to the difficulty of creating a submucosal tunnel for resection. The aim of this study was to evaluate the feasibility of STER using methylene-blue guidance for SETs originating from the MP layer in the cardia. From January 2012 to December 2014, 56 patients with SETs originating from the MP layer in the cardia were treated with STER using methylene-blue guidance...
September 26, 2016: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/27647414/assessing-empathic-attitudes-in-medical-students-the-re-validation-of-the-jefferson-scale-of-empathy-student-version-report
#14
Marija Petek Šter, Polona Selič
INTRODUCTION: Self-reported scales, such as the Jefferson Scale of Empathy - Student version (JSE-S), had been recognised to measure the empathic disposition rather than behavioural expression. This study aimed to re-validate the JSE-S and its factor structure prior further research on empathy in medical students. METHODS: A convenience sampling method was employed in two consecutive academic years, in 2012/13 and 2013/14, at the Faculty of Medicine in Ljubljana, Slovenia; first and final year students participated voluntarily...
December 2015: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/27597558/pearls-and-oy-sters-the-chapeau-de-gendarme-sign-and-other-localizing-gems-in-frontal-lobe-epilepsy
#15
Yee-Leng Tan, Wolfgang Muhlhofer, Robert Knowlton
No abstract text is available yet for this article.
September 6, 2016: Neurology
https://www.readbyqxmd.com/read/27551062/predictors-of-fever-related-admissions-to-a-paediatric-assessment-unit-ward-and-reattendances-in-a-south-london-emergency-department-the-cabin-2-study
#16
Amaya L Bustinduy, Irina Chis Ster, Rebecca Shaw, Adam Irwin, Jaiganesh Thiagarajan, Rhys Beynon, Shamez Ladhani, Mike Sharland
OBJECTIVE: To explore the risk factors for ward and paediatric assessment unit (PAU) admissions from the emergency department (ED). DESIGN: Prospective observational study. SETTING AND PATIENTS: Febrile children attending a large tertiary care ED during the winter of 2014-2015. MAIN OUTCOME MEASURES: Ward and PAU admissions, National Institute for Health and Care Excellence (NICE) guidelines classification, reattendance to the ED within 28 days and antibiotic use...
August 22, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27550898/pearls-oy-sters-niemann-pick-disease-type-c-in-a-65-year-old-patient
#17
Niraj Kumar, Philippe Rizek, Yahia Mohammad, Mandar Jog
No abstract text is available yet for this article.
August 23, 2016: Neurology
https://www.readbyqxmd.com/read/27462043/pearls-oy-sters-vascular-eds-presenting-with-acute-proptosis-always-revisit-the-history
#18
Amal P R Samaraweera, Etienne Laverse, Alex Henderson
No abstract text is available yet for this article.
July 26, 2016: Neurology
https://www.readbyqxmd.com/read/27432182/pearls-oy-sters-a-rare-presentation-of-chronic-intracranial-hypertension-with-concurrent-deafness-and-blindness
#19
Mersedeh Bahr Hosseini, Laura Stone McGuire, Milena Stosic, Heather E Moss, Michael D Carrithers
No abstract text is available yet for this article.
July 19, 2016: Neurology
https://www.readbyqxmd.com/read/27338009/women-with-congenital-factor-vii-deficiency-clinical-phenotype-and-treatment-options-from-two-international-studies
#20
M Napolitano, M N D Di Minno, A Batorova, A Dolce, M Giansily-Blaizot, J Ingerslev, J-F Schved, G Auerswald, G Kenet, M Karimi, T Shamsi, A Ruiz de Sáez, R Dolatkhah, A Chuansumrit, M A Bertrand, G Mariani
INTRODUCTION: A paucity of data exists on the incidence, diagnosis and treatment of bleeding in women with inherited factor VII (FVII) deficiency. AIM: Here we report results of a comprehensive analysis from two international registries of patients with inherited FVII deficiency, depicting the clinical picture of this disorder in women and describing any gender-related differences. METHODS: A comprehensive analysis of two fully compatible, international registries of patients with inherited FVII deficiency (International Registry of Factor VII deficiency, IRF7; Seven Treatment Evaluation Registry, STER) was performed...
September 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
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