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schmorl's nodes

Uruj Zehra, Luke Flower, Katharine Robson-Brown, Michael A Adams, Patricia Dolan
BACKGROUND CONTEXT: Bony vertebral endplates must be porous to allow metabolite transport into the disc, and yet strong to resist high intradiscal pressure. Endplate defects may therefore have nutritional and mechanical consequences for the disc, depending on their size and type. We hypothesise that broad, diffuse defects are more closely associated with disc decompression and degeneration than are focal Schmorl's node-type defects. PURPOSE: To determine how the size and type of endplate defects are related to decompression and degeneration in the adjacent intervertebral disc...
January 17, 2017: Spine Journal: Official Journal of the North American Spine Society
Jun Zhang, Fei Zhao, Feng-Liang Wang, Yong-Feng Yang, Chen Zhang, Yue Cao, You-Lin Wang, Xiao-Juan Shi, Yi Wan, Min Zhang, Meng-Qiao Liu, Chun-Guang Zuo, Hai-Qiang Wang
BACKGROUND: Lumbar disc disease has a disabling impact on global people with heavy burden on society, mainly consisting of lumbar disc degeneration (LDD) and lumbar disc herniation (LDH). The recently released lumbar disc nomenclature version 2.0 deepens our understandings on the diseases. Consequently, there is an urgent need to clarify the occurrence and distribution features of LDD and LDH in a large-scale sample in terms of the novel version. QUESTION/PURPOSES: We asked: (1) Is there a difference in the occurrence and distribution hallmarks of LDD and LDH in a population-based large-scale sample? (2) Does the novel nomenclature version bring novel vision on lumbar disc disease? METHODS: Five thousand two hundred eighty-eight consecutive cases (26,440 lumbar discs) undergoing lumbar spine MRI were retrospectively included from Jan 2008 to Dec 2010 in a territory university hospital...
2016: SpringerPlus
Zhengming Wang, Daqing Ma, Jigang Yang
BACKGROUND: Differentiation of vertebral metastases from Schmorl's nodes, especially with fluorine-18-fluorodeoxyglucose ((18)F-FDG) uptake, is very important for the appropriate management of these patients in case they have malignancy. We aimed to evaluate the value of (18)F-FDG positron emission tomography/computed tomography (PET/CT) in differentiating vertebral metastases from Schmorl's nodes with (18)F-FDG uptake. SUBJECTS AND METHODS: Fourteen patients with malignancy underwent (18)F-FDG PET/CT, which showed abnormal (18)F-FDG uptake in 19 Schmorl's nodes...
September 2016: Hellenic Journal of Nuclear Medicine
Hye Jin Yoo, Sung Hwan Hong, Dong Hyun Kim, Ja-Young Choi, Hee Dong Chae, Bo Mi Jeong, Joong Mo Ahn, Heung Sik Kang
PURPOSE: To determine whether fat-signal-fraction (FF) map using a modified Dixon sequence could help differentiate benign from malignant bone lesions. MATERIALS AND METHODS: Spine magnetic resonance images (MRIs) of 120 consecutive patients were studied by using a 3T MRI with standard T1 -weighted image (T1 WI) and modified-Dixon sequence for FF measurement. There were three groups: a control group (n = 51) with normal vertebrae; a benign group (n = 40) with focal red marrow deposition, Schmorl's nodes, benign compression fracture, or Modic type 1 endplate degeneration; a malignant group (n = 29) with spinal malignancies...
September 30, 2016: Journal of Magnetic Resonance Imaging: JMRI
S Rajasekaran, Rishi Mugesh Kanna, Ranjani Raja Reddy, Senthil Natesan, Muthuraja Raveendran, Kenneth Mc Cheung, Danny Chan, Patrick Yp Kao, Anita Yee, Ajoy Prasad Shetty
STUDY DESIGN: Prospective genetic association study OBJECTIVE.: To document the variations in the genetic associations, when different MRI phenotypes, age stratification, cohort size and sequence of cohort inclusion are varied in the same study population. SUMMARY OF BACKGROUND DATA: Genetic associations with disc degeneration have shown high inconsistency, generally attributed to hereditary factors and ethnic variations. However the effect of different phenotypes, size of the study population, age of the cohort etc have not been documented clearly...
August 10, 2016: Spine
Stephen Michael Sandelich, Terry A Adirim
A 10-year-old girl with a 2-week history of atraumatic back pain presented to the emergency department with difficulty ambulating and a history of 2 episodes of urinary incontinence in the past week. Her examination was significant for pain with movement, tenderness to palpation in the lower thoracic spine, and no neurological deficits. In this case, the child was found to have a Schmorl node at T8 in the superior aspect of the vertebral body. Schmorl nodes are protrusions of the cartilage of the intervertebral disc through the vertebral body endplate and into the adjacent that is more commonly reported in the adult population...
July 23, 2016: Pediatric Emergency Care
Devimeenal Jagannathan, Venkatraman Indiran, Fouzal Hithaya
INTRODUCTION: Schmorl's Nodes (SN), which appear as defects in superior and inferior endplates of vertebrae, are commonly seen around the thoracolumbar junction. They may be asymptomatic or symptomatic. Their prevalence varies with respect to age, gender, regions involved and other associated disc or vertebral findings. AIM: SN is quite a common finding on the Magnetic Resonance Imaging (MRI) of the spine. The purpose of the study was to evaluate the prevalence of SN in the patients who underwent MRI whole spine in the radiology department, ascertain its clinical relevance and to compare the prevalence of SN in the study population with the prevalence in rest of the Indian and global population described already in the literature...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
D Samartzis, F P S Mok, J Karppinen, D Y T Fong, K D K Luk, K M C Cheung
OBJECTIVE: Schmorl's nodes (SN) are highly associated with lumbar disc degeneration (DD). However, SN present with different morphologies/topographies that may be associated with varying degrees of DD. This study proposed a classification of SN to determine their morphological/topographical prevalence and association with the severity of DD. METHODS: Sagittal T2-weighted MRIs were assessed to identify SN and additional imaging findings from L1-S1 in 2,449 individuals...
October 2016: Osteoarthritis and Cartilage
Felix E Diehn, Timothy P Maus, Jonathan M Morris, Carrie M Carr, Amy L Kotsenas, Patrick H Luetmer, Vance T Lehman, Kent R Thielen, Ahmad Nassr, John T Wald
Beyond the familiar disk herniations with typical clinical features, intervertebral disk pathologic conditions can have a wide spectrum of imaging and clinical manifestations. The goal of this review is to illustrate and discuss unusual manifestations of intervertebral disk pathologic conditions that radiologists may encounter, including disk herniations in unusual locations, those with atypical imaging features, and those with uncommon pathophysiologic findings. Examples of atypical disk herniations presented include dorsal epidural, intradural, symptomatic thoracic (including giant calcified), extreme lateral (retroperitoneal), fluorine 18 fluorodeoxyglucose-avid, acute intravertebral (Schmorl node), and massive lumbar disk herniations...
May 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
M Moustarhfir, B Bresson, P Koch, A Perozziello, G Barreau, E Schouman-Claeys, M-C Henry-Feugeas, P Ou, B Dallaudière
PURPOSE: The purpose of our prospective study was to assess the presentation of Schmorl's nodes (SN) on magnetic resonance imaging (MRI) and investigate their possible association with demographic and clinical findings. MATERIALS AND METHODS: Three hundred and thirty-three patients were prospectively included. Thirteen (3.9%) patients were excluded because of contraindication to MRI and/or Scheuermann's disease. The final study population included 320 patients. T1-weighted and short TI inversion recovery sequences were performed to assess SN prevalence, the vertebral level and their anatomical distribution in vertebra...
April 2016: Diagnostic and Interventional Imaging
Julie A Nelson, Chang Y Ho, Meredith R Golomb
BACKGROUND: Acute monoplegia is a rare presentation for spinal cord stroke, which usually presents with paraplegia or paraparesis. PATIENT DESCRIPTION: We describe an athletic girl who presented after a week of heavy athletic activity complaining of back and left leg pain, followed by flaccid left leg paralysis. RESULTS: The prothrombotic evaluation was unremarkable. Cerebrospinal fluid studies demonstrated elevated myelin basic protein but no oligoclonal bands...
March 2016: Pediatric Neurology
Georgios Z Papadakis, Corina Millo, Ulas Bagci, Samira M Sadowski, Constantine A Stratakis
Schmorl node (SN) is the herniation of the nucleus pulposus through the cartilaginous and bony endplate into the adjacent vertebral body. It is documented that SNs produce areas of moderately increased F-FDG uptake. We present a case of a patient with history of neuroendocrine tumor, who underwent Ga DOTATATE PET/CT for follow-up, showing increased focal vertebral uptake suggestive of bone metastasis. CT revealed typical findings of an SN. The presented case indicates that SNs should be considered when encountering focally increased skeletal uptake in Ga DOTATATE PET/CT studies, which can mimic metastasis in patients with history of neuroendocrine tumors...
March 2016: Clinical Nuclear Medicine
Florence P S Mok, Dino Samartzis, Jaro Karppinen, Daniel Y T Fong, Keith D K Luk, Kenneth M C Cheung
BACKGROUND CONTEXT: Modic changes (MC) are bone marrow lesions on magnetic resonance imaging (MRI), suggestive of being associated with low back pain (LBP). Data on determinants of MC and their association with disc degeneration and other spinal phenotypes, as well as that of LBP, rely mostly on small-scale patient populations and remain controversial. PURPOSE: This study addressed the potential determinants of MC and their association with disc degeneration and LBP among Southern Chinese...
January 1, 2016: Spine Journal: Official Journal of the North American Spine Society
Seon Joo Park, Hyeun Sung Kim, Hyun Sook Kim, Seok Won Kim
A Schmorl's node is defined as a simple endplate intravertebral herniation resulting from trauma or idiopathic causes. Although Schmorl's nodes have been considered clinically insignificant, they might indicate an active symptomatic process or cause serious complications. In this study, we report an interesting case of complete separation of a vertebral body caused by an untreated Schmorl's node accompanying severe osteoporosis. To our knowledge, this is the first clinical report in the published literature to evaluate the complete separation of a vertebral body associated with a Schmorl's node...
August 2015: Journal of Korean Neurosurgical Society
Cory P Daignault, Edwin L Palmer, James A Scott, John S Swan, Gilbert H Daniels
A Schmorl's node is a common incidental finding encountered during radiologic imaging. Despite the vertebral body being a common site of metastatic disease, a lytic lesion adjacent to an endplate with typical imaging features can often confidently be called a Schmorl's node. This is a case report of a patient with a single well-defined FDG-avid papillary thyroid carcinoma metastasis to the spine that had imaging findings characteristic of a Schmorl's node on CT and MRI. This case is important to consider as it demonstrates that the imaging characteristics of metastatic disease and Schmorl's nodes can overlap...
September 2015: Nuclear Medicine and Molecular Imaging
Juhani H Määttä, Jaro I Karppinen, Keith D K Luk, Kenneth M C Cheung, Dino Samartzis
BACKGROUND CONTEXT: Modic changes (MC) are associated with low back pain. They represent vertebral endplate and adjacent vertebral marrow changes on magnetic resonance imaging (MRI), classified into three types. Because of small sample sizes, patient cohorts, and limited phenotype assessment, the morphology and involvement of MC and their association with other spinal phenotypes remain speculative. PURPOSE: We addressed and proposed a phenotypic profiling of MC and their relationship with lumbar MRI phenotypes in a large-scale population-based study...
September 1, 2015: Spine Journal: Official Journal of the North American Spine Society
Gabriele Masselli, Riccardo Monti, Marianna Guida, Gianfranco Gualdi
Bone metastasis in prostate cancer are detected by choline positron emission tomography/computed tomography (PET/CT) with high sensitivity and specificity. We report the case of a patient with previous prostatectomy for prostate cancer who underwent F-choline PET/CT for a recent increased of prostate-specific antigen value and showed focal vertebral uptake suggestive for skeletal metastasis; magnetic resonance imaging revealed unexpectedly a Schmorl's node (SN). False positives on choline PET-CT caused by SN has not be reported in the literature and the present case highlights that this possibility should be considered in case of choline vertebral increased uptake in the patient with prostate cancer...
May 2015: World Journal of Nuclear Medicine
Naoya Niwa, Toru Nishiyama, Choichiro Ozu, Yasuto Yagi, Shiro Saito
Bone is the third most common site of metastasis from upper tract urothelial carcinoma after radical nephroureterectomy. Although bone biopsy is the gold standard for the diagnosis of bone metastases, they can usually be diagnosed on the basis of imaging tests. We describe a case of upper tract urothelial carcinoma after radical nephroureterectomy presenting with a Schmorl node in the third lumbar vertebra, mimicking lytic bone metastasis. Differentiation of bone metastases from Schmorl nodes is essential for the appropriate management of patients with malignancy...
July 2015: Urology
Pokhraj Suthar, Rupal Patel, Chetan Mehta, Narrotam Patel
INTRODUCTION: Lower back pain secondary to degenerative disc disease is a condition that affects young to middle-aged persons with peak incidence at approximately 40 y. MRI is the standard imaging modality for detecting disc pathology due to its advantage of lack of radiation, multiplanar imaging capability, excellent spinal soft-tissue contrast and precise localization of intervertebral discs changes. AIMS AND OBJECTIVE: To evaluate the characterization, extent, and changes associated with the degenerative lumbar disc disease by Magnetic Resonance Imaging...
April 2015: Journal of Clinical and Diagnostic Research: JCDR
G Armbrecht, D Felsenberg, M Ganswindt, M Lunt, S K Kaptoge, K Abendroth, A Aroso, D Banzer, A K Bhalla, J Dequeker, R Eastell, K Hoszowski, G Lyritis, P D Delmas, P Masaryk, T Miazgowski, J Cannata, R Nuti, L Oei, G Poor, I Redlund-Johnell, D M Reid, W Reisinger, H Schatz, C J Todd, A D Woolf, K Javaid, F Rivadeneira, A J Silman, C Cooper, T W O'Neill, J Reeve
UNLABELLED: In 27 centres across Europe, the prevalence of deforming spinal Scheuermann's disease in age-stratified population-based samples of over 10,000 men and women aged 50+ averaged 8% in each sex, but was highly variable between centres. Low DXA BMD was un-associated with Scheuermann's, helping the differential diagnosis from osteoporosis. INTRODUCTION: This study aims to assess the prevalence of Scheuermann's disease of the spine across Europe in men and women over 50 years of age, to quantitate its association with bone mineral density (BMD) and to assess its role as a confounder for the radiographic diagnosis of osteoporotic fracture...
October 2015: Osteoporosis International
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