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https://www.readbyqxmd.com/read/29156108/optimizing-quality-of-dental-carving-by-preclinical-dental-students-through-anatomy-theory-reinforcement
#1
Renato A de Azevedo, Marcos B Correa, Marcos A Torriani, Rafael G Lund
Knowledge of dental anatomy is of great importance in the practice of dentistry, especially in oral rehabilitation, because without this knowledge, professional practice is not possible. Dental carving plays a major role in training dental students as it develops their manual dexterity. This randomized controlled trial aimed to evaluate the influence of didactic-theoretical reinforcement on the theoretical and practical knowledge of dental anatomy of preclinical students by examining the quality of the anatomical restorations performed by these students before and after a didactic-theoretical reinforcement...
November 20, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29155305/hey1-and-hey2-are-differently-expressed-during-mouse-tooth-development
#2
Kotono Kibe, Mitsushiro Nakatomi, Shinji Kataoka, Takashi Toyono, Yuji Seta
The Hey family (also known as Chf, Herp, Hesr, and Hrt) is a set of Hairy/Enhancer of Split-related basic helix-loop-helix type transcription factors. Hey1, Hey2, and HeyL have been identified in mammals. Although Hey proteins are known to regulate cardiovascular development, muscle homeostasis, osteogenesis, neurogenesis, and oncogenesis, their roles in tooth development have been largely obscure. Therefore, this study aimed to clarify detailed spatiotemporal expression patterns of Hey1 and Hey2 in developing molars and incisors of mice by section in situ hybridization...
November 16, 2017: Gene Expression Patterns: GEP
https://www.readbyqxmd.com/read/29154250/functional-endoscopic-sinus-surgery-fess-in-unilateral-sinus-disease
#3
Daniela Mielcarek-Kuchta, Karolina Simon, Dawid Kondratowicz, Zofia Łukomska, Aleksandra Rybak-Korytowska
BACKGROUND: Unilateral sinus disease (USD) occurs in 23 % of all cases. It is believed that it is mainly associated with cancer development. Retrospective data from large rhinological centers show that the most common USD is chronic rhinosinusitis (CRS), followed by mycosis, inverted papilloma and finally cancer, but only in a small percent of cases. THE AIM OF THE STUDY: The analysis of USD in the group of patients who underwent FESS at the secondary referral center...
October 30, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29152787/an-oral-hygiene-protocol-improves-oral-health-for-patients-in-inpatient-stroke-rehabilitation
#4
Joanne Murray, Ingrid Scholten
THE OBJECTIVE: To determine whether a simple oral hygiene protocol improves the oral health of inpatients in stroke rehabilitation. THE BACKGROUND DATA DISCUSSING THE PRESENT STATUS OF THE FIELD: Poor oral health can lead to serious complications, such as pneumonia. The comorbidities associated with stroke, such as dysphagia, hemiparesis and cognitive impairment, can further impede independent oral care. International stroke guidelines recommend routine oral care but stop short of detailing specific regimes...
November 20, 2017: Gerodontology
https://www.readbyqxmd.com/read/29150379/changes-in-maxillofacial-morphology-and-velopharyngeal-function-with-two-stage-maxillary-distraction-mandibular-setback-surgery-in-patients-with-cleft-lip-and-palate
#5
T Susami, Y Mori, K Ohkubo, M Takahashi, Y Hirano, H Saijo, T Takato
Maxillary distraction is increasingly used for the correction of severe maxillary retrusion in patients with cleft lip and palate. However, control of the maxillary movement is difficult, and the need to wear visible distractors for a long period of time causes psychosocial problems. A two-stage surgical approach consisting of maxillary distraction and mandibular setback was developed to overcome these problems. In this study, changes in maxillofacial morphology and velopharyngeal function were examined in 22 patients with cleft lip and palate who underwent this two-stage approach...
November 14, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29150134/stress-generation-in-mandibular-anterior-teeth-restored-with-different-types-of-post-and-core-at-various-levels-of-ferrule
#6
Anatolii Savychuk, Marianthi Manda, Christos Galanis, Christofer Provatidis, Petros Koidis
STATEMENT OF PROBLEM: Pertinent evidence regarding the mechanical integrity of mandibular anterior teeth restored with a post-and-core is limited. PURPOSE: The purpose of this finite element analysis study was to compare the impact of the post type (glass fiber post-and-resin core or cast post-and-core) along with the ferrule effect on the stress fields generated in endodontically treated mandibular lateral incisors and canines. MATERIAL AND METHODS: Three-dimensional models of the segmented mandible were developed...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29148207/esthetic-evaluation-of-implant-supported-single-crowns-the-implant-restoration-esthetic-index-and-patient-perception
#7
Xiachen Li, Bilin Wu, Xiaohui Cheng, Yiming Li, Xin Xie, Feilong Deng
PURPOSE: To test the validity and reliability of a newly developed Implant Restoration Esthetic Index (IREI) and to compare esthetic outcomes reported by patients and professionals. MATERIALS AND METHODS: Ten graduate students and 10 prosthodontists assessed esthetic outcomes of 27 single-tooth implants with the IREI. Six peri-implant soft tissue parameters were measured using visual analog scales: mesial papilla presence, distal papilla presence, gingival trigone, soft tissue curvature, alveolar process deficiency, and soft tissue color and texture, as well as the six crown parameters: crown contour, crown position, crown labial convexity, crown characterization, crown color and translucency, and abutment visibility...
November 17, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29148101/homeobox-protein-msx-1-inhibits-expression-of-bone-morphogenetic-protein-2-bone-morphogenetic-protein-4-and-lymphoid-enhancer-binding-factor-1-via-wnt-%C3%AE-catenin-signaling-to-prevent-differentiation-of-dental-mesenchymal-cells-during-the-late-bell-stage
#8
Xiao-Yu Feng, Xiao-Shan Wu, Jin-Song Wang, Chun-Mei Zhang, Song-Lin Wang
Homeobox protein MSX-1 (hereafter referred to as MSX-1) is essential for early tooth-germ development. Tooth-germ development is arrested at bud stage in Msx1 knockout mice, which prompted us to study the functions of MSX-1 beyond this stage. Here, we investigated the roles of MSX-1 during late bell stage. Mesenchymal cells of the mandibular first molar were isolated from mice at embryonic day (E)17.5 and cultured in vitro. We determined the expression levels of β-catenin, bone morphogenetic protein 2 (Bmp2), Bmp4, and lymphoid enhancer-binding factor 1 (Lef1) after knockdown or overexpression of Msx1...
November 17, 2017: European Journal of Oral Sciences
https://www.readbyqxmd.com/read/29143221/controlling-streptococcus-mutans-and-staphylococcus-aureus-biofilms-with-direct-current-and-chlorhexidine
#9
Hao Wang, Dacheng Ren
Microbial biofilms formed on biomaterials are major causes of chronic infections. Among them, Gram-positive bacteria Streptococcus mutans and Staphylococcus aureus are important pathogens causing infections associated with dental caries (tooth-decay) and other medical implants. Unfortunately, current antimicrobial approaches are ineffective in disrupting established biofilms and new methods are needed to improve the efficacy. In this study, we report that the biofilm cells of S. mutans and S. aureus can be effectively killed by low-level direct current (DC) and through synergy in concurrent treatment with DC and chlorhexidine (CHX) at low concentrations...
November 15, 2017: AMB Express
https://www.readbyqxmd.com/read/29142877/removal-efficacy-and-cytotoxicity-of-a-calcium-hydroxide-paste-using-n-2-methyl-pyrrolidone-as-a-vehicle
#10
Myung-Jin Lim, Hyun-Jin Jang, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
Objectives: This study investigated the removal efficacy and cytotoxicity of a newly developed calcium hydroxide paste (cleaniCal, Maruchi) using N-2-methyl-pyrrolidone (NMP) as a vehicle in comparison with ApexCal (Ivoclar Vivadent) and Calcipex II (Nishika), which use different vehicles such as polyethylene glycol and propylene glycol, respectively. Materials and Methods: Thirty maxillary premolars with oval-shaped canals were divided into 3 groups and the teeth were filled with one of the pastes...
November 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/29140096/redesigning-existing-provisional-restorations-while-maintaining-established-transmucosal-anatomy-in-a-multi-implant-system-natural-tooth-full-arch-case
#11
Michael A Weiss, Barry P Levin, Kevan S Green
Redesigning existing provisional restorations when a combination of two different implant systems and natural teeth exist in the same arch can be challenging. Problems such as acrylic locking into undercuts and loss of spatial landmarks both subgingivally and supragingivally are common concerns for the practitioner. Two techniques, presented herein, offer treatment options to retain the previously developed transmucosal anatomies of implant-level provisional abutments while allowing for redesign of the clinical crown component of the same long-term provisional restorations...
November 2017: Compendium of Continuing Education in Dentistry
https://www.readbyqxmd.com/read/29139600/arcr-modulates-biofilm-formation-in-the-dental-plaque-colonizer-streptococcus-gordonii
#12
Jill C Robinson, Nadia Rostami, John Casement, Waldemar Vollmer, Alexander H Rickard, Nicholas S Jakubovics
Biofilm formation and cell-cell sensing by the pioneer dental plaque coloniser Streptococcus gordonii is dependent upon arginine. This study aimed to identify genetic factors linking arginine-dependent responses and biofilm formation in S. gordonii. Isogenic mutants disrupted in genes required for biosynthesis or catabolism of arginine, or for arginine-dependent gene regulation, were screened for their ability to form biofilms in a static culture model. Biofilm formation by a knockout mutant of arcR, encoding an arginine-dependent regulator of transcription, was reduced to <50% that of the wild-type whereas other strains were unaffected...
November 15, 2017: Molecular Oral Microbiology
https://www.readbyqxmd.com/read/29139559/associations-among-tooth-loss-systemic-inflammation-and-antibody-titers-to-periodontal-pathogens-in-japanese-patients-with-cardiovascular-disease
#13
N Aoyama, J-I Suzuki, N Kobayashi, T Hanatani, N Ashigaki, A Yoshida, Y Shiheido, H Sato, M Minabe, Y Izumi, M Isobe
BACKGROUND AND OBJECTIVE: It is well known that there is a strong relationship between periodontitis and cardiovascular disease (CVD). Tooth loss reflects an end-stage condition of oral diseases, such as periodontitis. Infection with specific periodontal pathogens is known as a possible factor that influences development of CVD. The aim of this study was to assess the relationship between the number of residual teeth and systemic inflammatory conditions in patients with CVD. MATERIAL AND METHODS: We divided 364 patients with CVD into four groups, according to the number of residual teeth: (i) ≥20 teeth; (ii) 10-19 teeth; (iii) 1-9 teeth; and (iv) edentulous...
November 15, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29137807/mapping-the-mechanical-gradient-of-human-dentin-enamel-junction-at-different-intratooth-locations
#14
Zhengzhi Wang, Kun Wang, Wanyin Xu, Xiaoyu Gong, Feiyu Zhang
OBJECTIVES: The local structures and mechanical properties within tooth dentin-enamel-junction (DEJ) regions have been focused for numerous studies. The reported results, however, remain inconsistent particularly on the functional width and gradient architecture of the DEJ. The current study aims at systematically determining the mechanical gradient of the DEJ at different intratooth locations such that a clearer understanding on the tooth properties and the potential correlations with the tooth function could be obtained...
November 11, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/29132069/risk-factors-for-tooth-loss-in-middle-and-older-age-after-up-to-10-years-an-observational-cohort-study
#15
Alexander Jochen Hassel, Volkan Safaltin, Sabine Grill, Johannes Schröder, Hans-Werner Wahl, Anna-Luisa Klotz, Edriss Habibi, Peter Rammelsberg, Andreas Zenthöfer
OBJECTIVE: The objective of this research was to identify risk factors for tooth loss in two birth cohorts, quinquagenarians and septuagenarians, after up to 10 years of clinical observation. DESIGN: One hundred and twenty-three participants were recruited from the Interdisciplinary Study of Adult Development (ILSE) and examined at baseline and up to 10 years after. Thirty-nine and 84 participants belonged to the older (OC; born in 1930/32) cohort and younger (YC; born in 1950/52) cohort, respectively...
November 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29131694/role-of-neuron-glial-interaction-mediated-by-il-1%C3%AE-in-ectopic-tooth-pain
#16
H Komiya, K Shimizu, N Noma, Y Tsuboi, K Honda, K Kanno, K Ohara, M Shinoda, B Ogiso, K Iwata
Although many reports have demonstrated that ectopic pain develops in the orofacial region following tooth pulp inflammation, which often causes misdiagnosis and inappropriate treatment for patients with pulpitis, the precise mechanism remains unknown. In the present study, we hypothesized that the functional interaction between satellite glial cells and neurons mediated by interleukin 1β (IL-1β) in the trigeminal ganglion (TG) is involved in ectopic orofacial pain associated with tooth pulp inflammation...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29130364/fluorescent-labeling-and-2-photon-imaging-of-mouse-tooth-pulp-nociceptors
#17
A Kadala, P Sotelo-Hitschfeld, Z Ahmad, P Tripal, B Schmid, A Mueller, L Bernal, Z Winter, S Brauchi, U Lohbauer, K Messlinger, J K Lennerz, K Zimmermann
Retrograde fluorescent labeling of dental primary afferent neurons (DPANs) has been described in rats through crystalline fluorescent DiI, while in the mouse, this technique was achieved with only Fluoro-Gold, a neurotoxic fluorescent dye with membrane penetration characteristics superior to the carbocyanine dyes. We reevaluated this technique in the rat with the aim to transfer it to the mouse because comprehensive physiologic studies require access to the mouse as a model organism. Using conventional immunohistochemistry, we assessed in rats and mice the speed of axonal dye transport from the application site to the trigeminal ganglion, the numbers of stained DPANs, and the fluorescence intensity via 1) conventional crystalline DiI and 2) a novel DiI formulation with improved penetration properties and staining efficiency...
November 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/29129749/quantitative-proteomic-analysis-of-deciduous-molars-during-cap-to-bell-transition-in-miniature-pig
#18
Yang Li, Yiyi Gong, Xiaoshan Wu, Fu Wang, Yilin Xie, Zhao Zhu, Yingying Su, Jinsong Wang, Chunmei Zhang, Junqi He, Haiteng Deng, Songlin Wang
Taking advantage of genetic manipulation tools and accessibility, almost all molecular knowledge on vertebrate tooth development was obtained from rodent models that only have one dentition in their entire lives. Whether the tooth development in other vertebrates such as swine or human follows the same rules remains elusive. Rodent dentitions differ considerably from human dentitions, therefore limiting the application of knowledge from rodent tooth to human tooth. Signal-mediated communication between cells and complex gene and protein regulatory networks are key components of tooth development...
November 10, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/29126984/osteopontin-as-a-novel-substrate-for-the-proprotein-convertase-5-6-pcsk5-in-bone
#19
Betty Hoac, Delia Susan-Resiga, Rachid Essalmani, Edwige Marcinkiweicz, Nabil G Seidah, Marc D McKee
Seven proprotein convertases cleave the basic amino acid consensus sequence K/R-Xn-K/R↓ (where n=0, 2, 4 or 6 variable amino acids) to activate precursor proteins. Despite similarities in substrate specificity, basic amino acid-specific proprotein convertases have a distinct tissue distribution allowing for enzymatic actions on tissue-resident substrates. Proprotein convertase 5/6 (PC5/6) has two splice variants - soluble PC5/6A and membrane-bound PC5/6B - and is expressed during mouse development in many tissues including bone and tooth, but little is known about the substrates for PC5/6 therein...
November 7, 2017: Bone
https://www.readbyqxmd.com/read/29125503/patient-preferences-for-treatments-of%C3%A2-neuromuscular-diseases-a-systematic-literature-review
#20
Erik Landfeldt, Josefin Edström, Peter Lindgren, Hanns Lochmüller
BACKGROUND: Treatment decisions of neuromuscular diseases involve weighing clinical benefits and risks, as well as impact on patient social life, work status, other activities of daily living, and health-related quality of life. OBJECTIVE: To conduct a systemic literature review of patient preferences for treatments of neuromuscular diseases. METHODS: We searched Embase, Web of Science, and PubMed for full-text articles reporting results from studies of patient preferences for treatments of neuromuscular diseases...
November 8, 2017: Journal of Neuromuscular Diseases
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