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HIV and Quality of Life

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https://www.readbyqxmd.com/read/29327518/a-study-of-cardiovascular-abnormalities-in-hiv-positive-patients-in-a-tertiary-care-hospital-in-northern-india
#1
Shyam Chaudhary, Apurva, Kamal Kumar Sawlani, D Himanshu Reddy, Sharad Chandra Yadav, Munna Lal Patel, Anil Kumar Tripathi, Arvind Kumar Vaish
Introduction: Cardiovascular illness is common in patients with HIV infection, particularly in the later course of disease. Cardiovascular abnormalities in people living with HIV disease (PLHIV) often go unrecognized or untreated resulting in increased cardiovascular related morbidity and mortality and reduced quality of life. The prevalence of cardiac involvement in PLHIV has been reported to range between 28 to 73%. However, the incidence of symptomatic heart failure in HIV positive patients is 8-10%...
December 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29323557/neuropsychological-assessment-of-412-hiv-infected-individuals-in-s%C3%A3-o-paulo-brazil
#2
Maria Rita Polo Gascón, José Ernesto Vidal, Yolanda Marques Mazzaro, Jerusa Smid, Rosa Maria Nascimento Marcusso, Claudio Garcia Capitão, Elizeu Macedo Coutinho, Glaucia Rosana Guerra Benute, Mara Cristina Souza De Lucia, Augusto César Penalva de Oliveira
HIV-associated neurocognitive disorders (HAND) remain frequent even among individuals receiving combined antiretroviral therapy (cART). In addition, HAND may adversely affect the quality of life and adherence to cART. There is scarce epidemiological information about HAND in Latin America. This cross-sectional study recruited HIV-infected patients from a tertiary teaching institution in São Paulo, Brazil, between May 2013 and February 2015. The patients were adults with at least 4 years of education and patients with current neurological or psychiatric diseases were excluded...
January 2018: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/29323108/clinical-study-of-tuberculosis-in-the-head-and-neck-region-11-years-experience-and-a-review-of-the-literature
#3
Pai Pang, Weiyi Duan, Shuchun Liu, Shuang Bai, Yanan Ma, Ruiwu Li, Fayu Liu, Changfu Sun
Tuberculosis (TB) is an infectious disease and major health concern. Head and neck tuberculosis (HNTB) is relatively rare, but can arise in many regions, including the lymph nodes, larynx, oral cavity and pharynx. We retrospectively reviewed the clinical records of 60 patients diagnosed with HNTB in our department between March 2005 and January 2016. A review and summary of previous HNTB articles published in PubMed since 1885 was also performed. The subjects consisted of 17 males and 43 females, and the average age of patients was 45 ± 14...
January 10, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29313284/endocrinological-aspects-of-hiv-infection
#4
REVIEW
F S Mirza, P Luthra, L Chirch
PURPOSE: Patients with human immunodeficiency virus (HIV) are living longer with effective antiretroviral therapies and are enjoying near normal life span. Therefore, they are encountering endocrine issues faced by the general population along with those specific to HIV infection. The purpose of this article is to review the common endocrine aspects of HIV infection, and the early detection and management strategies for these complications. METHODS: Recent literature on HIV and endocrine disease was reviewed...
January 8, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29297790/burden-of-care-among-caregivers-of-persons-living-with-hiv-aids-in-rural-namibia-correlates-and-outcomes
#5
Eveline Ndinelao Kalomo, Minli Liao
This study examined the correlates of burden of caregivers providing care to people living with HIV/AIDS in rural northern Namibia and the consequences of caregivers' burden on their physical health and mental health. A purposive sampling method was used to recruit a total of 97 primary caregivers (N = 97) in rural Namibia. We found that hunger and HIV stigma were both positively associated with caregiver burden. Caregiver burden was positively related to depression and negatively related to quality of life...
2018: Social Work in Public Health
https://www.readbyqxmd.com/read/29297112/relationship-among-hiv-related-stigma-mental-health-and-quality-of-life-for-hiv-positive-patients-in-tehran
#6
Mehrnaz Rasoolinajad, Nasrin Abedinia, Ahmad Ali Noorbala, Minoo Mohraz, Banafsheh Moradmand Badie, Abdulqader Hamad, Leyla Sahebi
People living with HIV/AIDS (PLHA) face several challenges in terms of the medical management of their disease. Alongside this are stigma, discrimination and psychosocial issues associated with HIV infection. In this study, the relationships associated with HIV-related stigma, mental health and quality of life for HIV-positive patients were investigated. This cross-sectional study examined a sample of 450 HIV positive patients from the Infectious Diseases and Behavioral Health Clinic of Imam Khomeini Hospital in the city of Tehran, Iran...
January 2, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29295020/disclosing-sex-trading-histories-to-providers-barriers-and-facilitators-to-navigation-of-social-services-among-women-impacted-by-commercial-sexual-exploitation
#7
Lara Gerassi, Tonya E Edmond, Vanessa Fabbre, Abby Howard, Andrea J Nichols
Sex trafficking and commercial sexual exploitation (CSE) can lead to devastating health and mental health consequences for women, such as elevated rates of substance use, trauma, posttraumatic stress disorder, depression, sexually transmitted infections (STIs), and HIV. Consequently, engagement with services that address addiction, mental health, and housing, and provide general advocacy is critically important to women's increased safety, stabilization, and quality of life. The purpose of this study is to identify perceived barriers and facilitators to service access and engagement with social services among women involved in CSE...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29277410/hiv-related-stigma-racial-discrimination-and-gender-discrimination-pathways-to-physical-and-mental-health-related-quality-of-life-among-a-national-cohort-of-women-living-with-hiv
#8
Carmen H Logie, Ying Wang, Ashley Lacombe-Duncan, Anne C Wagner, Angela Kaida, Tracey Conway, Kath Webster, Alexandra de Pokomandy, Mona R Loutfy
Social inequities compromise health-related quality of life (HR-QoL) among women living with HIV (WLWH). Little is known about health impacts of intersecting stigma based on HIV status, race and gender among WLWH or potential mechanisms to promote HR-QoL. We tested pathways from multiple types of stigma (HIV-related, racial, gender) to physical and mental HR-QoL utilizing baseline survey data from a national cohort of WLWH in Canada (2013-2015). Structural equation modeling was conducted using maximum likelihood estimation methods to test the direct effects of HIV-related stigma, racial discrimination and gender discrimination on HR-QoL and indirect effects via social support and economic insecurity, adjusting for socio-demographic factors...
December 22, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29258342/gender-differences-in-health-related-quality-of-life-at-the-time-of-a-positive-hiv-test-a-cross-sectional-study-in-a-resource-poor-high-prevalence-setting-in%C3%A2-nairobi-kenya
#9
Mia L van der Kop, Samuel Muhula, Anik Patel, Lehana Thabane, Patricia Awiti, Lennie Kyomuhangi, Bonface Abunah, Patrick I Nagide, Kirsten Smillie, David I Ojakaa, Joshua Kimani, Anna Mia Ekström, Richard T Lester
Few studies have examined gender differences in sub-Saharan Africa, where HIV disproportionately affects women. Objectives of this cross-sectional study were to determine gender differences in HRQoL at the time of a positive HIV test, and whether factors associated with HRQoL differed between men and women. Adults testing HIV-positive were recruited from two clinics located in informal settlements. HRQoL was measured with the SF-12. Multiple linear regression was used to test whether there were gender differences in physical (PCS) and mental composite summary (MCS) scores...
December 19, 2017: AIDS Care
https://www.readbyqxmd.com/read/29246657/consequences-of-restricted-sti-testing-for-young-heterosexuals-in-the-netherlands-on-test-costs-and-qaly-losses
#10
Anita W M Suijkerbuijk, Eelco A B Over, Fleur van Aar, Hannelore M Götz, Birgit H B van Benthem, Anna K Lugnér
BACKGROUND: Due to rising costs caused by increasing demand for sexually transmitted infection (STI) care, the Dutch government changed the funding of STI clinics. In 2015, a more restrictive testing policy was introduced with syphilis and HIV tests only on indication for younger, heterosexual clients. We evaluated intended savings and missed syphilis and/or HIV infections and explored efficiency of possible test policies. METHODS: Using surveillance data from 2011 to 2013 with extensive testing for all, we estimated effects of restrictive testing on test costs, number of infections missed, costs per Quality Adjusted Life Year (QALY) lost, and calculated the net monetary benefit from a government perspective...
December 8, 2017: Health Policy
https://www.readbyqxmd.com/read/29228820/associations-between-depressive-symptomatology-and-neurocognitive-impairment-in-hiv-aids
#11
Sarah Tymchuk, Daniela Gomez, Noshin Koenig, M John Gill, Esther Fujiwara, Christopher Power
OBJECTIVE: Mood disorders and neurocognitive impairments are debilitating conditions among patients with HIV/AIDS. How these comorbidities interact and their relationships to systemic factors remain uncertain. Herein, we investigated factors contributing to depressive symptomatology (DS) in a prospective cohort of patients with HIV/AIDS in active care that included neuropsychological assessment. METHODS: Among patients with HIV/AIDS receiving combination antiretroviral therapy (cART) and ongoing clinical assessments including measures of sleep, health-related quality of life (HQoL), neuropsychological testing, and mood evaluation (Patient Health Questionnaire-9 [PHQ-9]) were performed...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29223583/the-global-burden-of-tuberculosis-results-from-the-global-burden-of-disease-study-2015
#12
(no author information available yet)
BACKGROUND: An understanding of the trends in tuberculosis incidence, prevalence, and mortality is crucial to tracking of the success of tuberculosis control programmes and identification of remaining challenges. We assessed trends in the fatal and non-fatal burden of tuberculosis over the past 25 years for 195 countries and territories. METHODS: We analysed 10 691 site-years of vital registration data, 768 site-years of verbal autopsy data, and 361 site-years of mortality surveillance data using the Cause of Death Ensemble model to estimate tuberculosis mortality rates...
December 6, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29222081/media-consumption-and-creation-in-attitudes-toward-and-knowledge-of-inflammatory-bowel-disease-web-based-survey
#13
Jacob Groshek, Miles Basil, Ling Guo, Sarah Parker Ward, Francis A Farraye, Jason Reich
BACKGROUND: Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition affecting over 5 million people globally and 1.6 million in the United States but currently lacks a precisely determined cause or cure. The range of symptoms IBD patients experience are often debilitating, and the societal stigmas associated with some such symptoms can further degrade their quality of life. Better understanding the nature of this public reproach then is a critical component for improving awareness campaigns and, ultimately, the experiences of IBD patients...
December 8, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29220598/hope-for-the-future-but-fear-the-risk-of-stigma-ethiopian-family-caregivers-lived-experience-of-caring-for-their-hiv-positive-child-two-years-after-starting-antiretroviral-treatment
#14
Mulatu Biru, Pia Lunqvist, Mitikie Molla, Degu Jerene, Inger Hallström
Family caregivers are believed to be the primary source of support for HIV-affected children. There is limited evidence about practices of support for caregivers, to strengthen them and to enhance the welfare of HIV positive children, especially in African settings. Our aim was therefore to illuminate caregivers' lived experiences of caring for a child in Ethiopia 2 years after the child was enrolled in antiretroviral therapy. Qualitative interviews with 18 family caregivers of 18 children were performed and analyzed using an inductive design with a hermeneutic phenomenological approach...
December 8, 2017: Comprehensive Child and Adolescent Nursing
https://www.readbyqxmd.com/read/29219811/non-targeted-hiv-screening-in-emergency-departments-in-the-netherlands
#15
G P M Luiken, I K Joore, A Taselaar, S C E Schuit, S E Geerlings, A Govers, P P M Rood, J M Prins, B E Nichols, A Verbon, T E M S de Vries-Sluijs
BACKGROUND: In the Netherlands a substantial proportion of newly diagnosed human immunodeficiency virus (HIV) patients present late for care and an estimated 12-34% of people living with HIV are undiagnosed. Linkage to care of these patients is important to decrease HIV transmission and to improve individual patient outcomes. We investigated if non-targeted HIV testing in emergency departments is a useful and cost-effective way to identify these patients. METHODS: In a cross-sectional multicentre study, eligible adult patients who underwent phlebotomy were given an active choice to be additionally tested for HIV...
November 2017: Netherlands Journal of Medicine
https://www.readbyqxmd.com/read/29210832/quality-of-caregiving-is-positively-associated-with-neurodevelopment-during-the-first-year-of-life-among-hiv-exposed-uninfected-children-in-uganda
#16
Itziar Familiar, Shalean M Collins, Alla Sikorskii, Horacio Ruisenor-Escudero, Barnabas Natamba, Paul Bangirana, Elizabeth M Widen, Daniel Achidri, Harriet Achola, Daniel Onen, Michael Boivin, Sera L Young
OBJECTIVE: We sought to evaluate if maternal characteristics and infant developmental milieu were predictive of early cognitive development in HIV-exposed uninfected (HEU) and un-exposed uninfected (HU) infants in Uganda. DESIGN: Longitudinal pregnancy study. METHODS: Ugandan women (n=228) were enrolled into the Postnatal Nutrition and Psychosocial Health Outcomes (PostNAPS) study with a 2:1 HIV-uninfected:infected ratio. Maternal socio-demographic, perceived social support, and depressive symptomatology were assessed...
November 27, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29204296/quality-of-life-of-people-living-with-hiv-aids-in-the-ho-municipality-ghana-a-cross-sectional-study
#17
James Osei-Yeboah, William K B A Owiredu, Gameli Kwame Norgbe, Sylvester Yao Lokpo, Christian Obirikorang, Emmanuel Alote Allotey, John Gameli Deku, Emmanuel Akomanin Asiamah, Nana Yaw Barimah Manaphraim, Prince Senyo Kwasi Nyamadi, Edward Yiadom Boakye, Tibemponi Ntoni, Roseline Avorkliyah, Romeo Asumbasiya Aduko, Seyram Tetteh Quarshie, Maxwell Jenkins Gbemu
Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). This study was aimed at evaluating the QoL of PLHIV attending the antiretroviral clinics in the Ho municipality. A cross-sectional study was conducted from January 2017 to April 2017 involving 158 purposively selected HIV-positive patients who were attending the antiretroviral clinics both in the Volta Regional Hospital and Ho Municipal Hospital. An Interviewer administered standard questionnaire (WHOQOL-HIV Bref) was used to collect information on sociodemography, medical history, and the quality of life (QoL) of the respondents...
2017: AIDS Research and Treatment
https://www.readbyqxmd.com/read/29189172/cardiovascular-complications-of-human-immunodeficiency-virus-infection
#18
Daniela Sofia Martins Pinto, Manuel Joaquim Lopes Vaz da Silva
BACKGROUND: Since the introduction of antiretroviral therapy (ART), the life expectancy and health quality for patients infected with human immunodeficiency virus (HIV) have significantly improved. Nevertheless, as a result of not only the deleterious effects of the virus itself and prolonged ART, but also the effects of aging, cardiovascular diseases have emerged as one of the most common causes of death among these patients. OBJECTIVE: The purpose of this review is to explore the new insights on the spectrum of cardiovascular disease (CVD) in HIV infection, with emphasis on the factors that contribute to the atherosclerotic process and its role in the development of acute coronary syndrome in the setting of infection...
November 29, 2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/29186458/four-days-a-week-antiretroviral-maintenance-therapy-in-virologically-controlled-hiv-1-infected-adults-the-anrs-162-4d-trial
#19
Pierre de Truchis, Lambert Assoumou, Roland Landman, Dominique Mathez, Damien Le Dû, Jonathan Bellet, Karine Amat, Christine Katlama, Guillaume Gras, Olivier Bouchaud, Martin Duracinsky, Emuri Abe, Jean-Claude Alvarez, Jacques Izopet, Juliette Saillard, Jean-Claude Melchior, Jacques Leibowitch, Dominique Costagliola, Pierre-Marie Girard, Christian Perronne
Background: Intermittent treatment could improve the convenience, tolerability and cost of ART, as well as patients' quality of life. We conducted a 48 week multicentre study of a 4-days-a-week antiretroviral regimen in adults with controlled HIV-1-RNA plasma viral load (VL). Methods: Eligible patients were adults with VL < 50 copies/mL for at least 1 year on triple therapy with a ritonavir-boosted PI (PI/r) or an NNRTI. The study protocol consisted of the same regimen taken on four consecutive days per week followed by a 3 day drug interruption...
November 25, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29183228/recommendations-for-buprenorphine-and-methadone-therapy-in-opioid-use-disorder-a-european-consensus
#20
Maurice Dematteis, Marc Auriacombe, Oscar D'Agnone, Lorenzo Somaini, Néstor Szerman, Richard Littlewood, Farrukh Alam, Hannu Alho, Amine Benyamina, Julio Bobes, Jean Pierre Daulouede, Claudio Leonardi, Icro Maremmani, Marta Torrens, Stephan Walcher, Michael Soyka
Management of patients with opioid use disorder (OUD) commonly includes opioid agonist therapy (OAT) as a part of an integrated treatment plan. These interventions are associated with proven benefits to the individual and society. Areas covered: The use of methadone and buprenorphine within an integrated treatment plan in the management of patients with OUD: this work provides consensus recommendation on pharmacotherapy in OUD to assist clinicians with practical decision making in this field. Expert opinion: Pharmacotherapy is recommended as part of an integrated OUD treatment approach with psychosocial interventions, with the goal of reducing risks of illicit opioid use, overdose mortality, infection with HIV or HCV, improving health, psychological and social outcomes...
November 29, 2017: Expert Opinion on Pharmacotherapy
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