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HIV and Quality of Life

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https://www.readbyqxmd.com/read/28637906/anogenital-warts-and-other-hpv-associated-anogenital-lesions-in-the-hiv-positive-patient-a-systematic-review-and-meta-analysis-of-the-efficacy-and-safety-of-interventions-assessed-in-controlled-clinical-trials
#1
Ricardo Niklas Werner, Lukas Westfechtel, Corinna Dressler, Alexander Nast
OBJECTIVES: Anogenital warts (AGW, condylomata acuminata) and intraepithelial neoplasia (IEN) do not only impact health and social well-being, they are also associated with considerable costs for the healthcare systems. Immunocompromised and HIV-positive patients carry the highest epidemiological burden of human papillomavirus (HPV) infection and comprise a population specifically susceptible to treatment failures and recurrences. This systematic review aimed at identifying and appraising the available evidence from controlled studies of interventions for the treatment of AGW and IEN in immunocompromised patients...
June 21, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28631491/a-longitudinal-examination-of-factors-associated-with-social-support-satisfaction-among-hiv-positive-young-black-men-who-have-sex-with-men
#2
Charlotte McCullagh, Katherine Quinn, Dexter R Voisin, John Schneider
This study examined the long-term predictors of social support satisfaction among HIV-positive young Black men who have sex with men (YBMSM). Data were collected across three waves between October 2012 and November 2014 as part of the baseline assessment from Project nGage, a preliminary efficacy randomized control study examining the role of social support in improving HIV care among YBMSM. The sample included 92 YBMSM aged 18-29. Major results controlling for age, education and intervention effects indicated that psychological health, social network size, and education at baseline predicted differences in social support satisfaction at Wave 3, with no significant effects based on length of HIV diagnosis...
June 20, 2017: AIDS Care
https://www.readbyqxmd.com/read/28623928/the-effects-of-beliefs-about-aids-related-death-on-quality-of-life-in-chinese-married-couples-with-both-husband-and-wife-infected-with-hiv-examining-congruence-using-the-actor-partner-interdependence-model
#3
Nancy Xiaonan Yu
BACKGROUND: This cross-sectional study examined the actor and partner effects of beliefs about AIDS-related death on quality of life in Chinese married couples in which both were living with HIV. METHODS: A total of 49 married couples in central China who were both infected with HIV completed measures to assess their beliefs about AIDS-related death and quality of life. RESULTS: In the actor-partner interdependence model, the husband-wife dyad showed congruence in their beliefs about AIDS-related death (r = ...
June 17, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28619295/effects-of-massage-therapy-on-anxiety-depression-hyperventilation-and-quality-of-life-in-hiv-infected-patients-a-randomized-controlled-trial
#4
Reychler Gregory, Caty Gilles, Arcq Aude, Lebrun Laurie, Belkhir Leïla, Yombi Jean-Cyr, Marot Jean-Christophe
INTRODUCTION: HIV infection is often preceded or accompanied by psychiatric comorbidities. These disorders improve with complementary therapies. The aim of this study was to measure the effect of massage therapy on anxiety, depression, hyperventilation and quality of life in HIV infected patients. METHOD: Adult HIV-infected patients were randomized (n=29) in massage therapy group (one hour a week during four weeks) and control group. Anxiety and depression (HADS-A and HADS-D), hyperventilation (Nijmegen questionnaire) and quality of life (WHOQOL-HIV) were evaluated at inclusion and after 4 weeks...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28619271/the-impact-of-motivational-interviewing-on-adherence-and-symptom-severity-in-adolescents-and-young-adults-with-chronic-illness-a-systematic-review
#5
REVIEW
Megan R Schaefer, Jan Kavookjian
OBJECTIVE: Given the negative consequences associated with non-adherence in adolescents and young adults (AYAs) with chronic illness, it is important to identify interventions to address this issue. Therefore, this review's primary objective is to evaluate the impact of motivational interviewing (MI) on adherence and symptom level/severity in AYAs with chronic illness using a modified Cochrane method. METHOD: Four databases (e.g., CINAHL, Medline, PsychINFO, and International Pharmaceutical Abstracts) were systematically reviewed...
June 12, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28617733/economic-costs-and-health-related-quality-of-life-outcomes-of-hiv-treatment-after-self-and-facility-based-hiv-testing-in-a-cluster-randomized-trial
#6
Hendramoorthy Maheswaran, Stavros Petrou, Peter MacPherson, Felistas Kumwenda, David G Lalloo, Elizabeth L Corbett, Aileen Clarke
BACKGROUND: The scale-up of HIV self-testing (HIVST) in Africa is recommended, but little is known about how this novel approach influences economic outcomes following subsequent antiretroviral treatment (ART) compared with established facility-based HIV testing and counseling (HTC) approaches. SETTING: HIV clinics in Blantyre, Malawi. METHODS: Consecutive HIV-positive participants, diagnosed by HIVST or facility-based HTC as part of a community cluster-randomized trial (ISRCTN02004005), were followed from initial assessment for ART until 1-year postinitiation...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28605418/should-we-be-testing-for-baseline-integrase-resistance-in-patients-newly-diagnosed-with-hiv
#7
Yiannis Koullias, Paul E Sax, Naomi F Fields, Rochelle P Walensky, Emily P Hyle
Background: Current guidelines recommend genotype resistance testing at diagnosis to guide initial selection of antiretroviral therapy (ART). Many standard resistance genotypes exclude testing for resistance to integrase inhibitors ("IR-testing"), although this class of drugs is a component of most recommended first-line regimens. Methods: We compared the 96-week clinical outcomes and cost-effectiveness of two strategies: no IR-testing vs. IR-testing performed at HIV diagnosis...
June 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28591373/-vulnerability-to-hiv-infection-in-serodiscordant-couples-in-rio-de-janeiro-brazil
#8
Nilo Martinez Fernandes, Élida Azevedo Hennington, Jefferson de Souza Bernardes, Beatriz G Grinsztejn
A new era in HIV/AIDS treatment began in 1996 with the advent of highly active antiretroviral therapy (HAART). The advent of these new medicines expanded the treatment resources and improved life expectancy and quality of life for persons living with HIV and AIDS, favoring the maintenance and initiation of relationships between partners with discordant HIV serological status. The main objective of this study with serodiscordant couples was to understand the three dimensions of vulnerability - programmatic, social, and individual - in these couples...
June 1, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28591161/health-related-quality-of-life-among-military-hiv-patients-on-antiretroviral-therapy
#9
Leonard Emuren, Seth Welles, Alison A Evans, Marcia Polansky, Jason F Okulicz, Grace Macalino, Brian K Agan
OBJECTIVE: The aims of this study were: (i) to determine the factors associated with HRQOL at baseline in our cohort, and (ii) to evaluate if there are differences in baseline HRQOL measures by antiretroviral treatment. METHODS: The Short Form 36 (SF-36) was administered between 2006 and 2010 among members of the United States HIV Natural History Study cohort (NHS), and participants who completed the SF-36 were included in the study. Physical component summary (PCS) and mental component summary (MCS) scores were computed based on standard algorithms...
2017: PloS One
https://www.readbyqxmd.com/read/28589797/use-of-the-wellness-thermometer-to-improve-consultations-for-patients-with-human-immunodeficiency-virus
#10
Michelle Croston, Jenny Petrak, Andrew Ustianowski
The care paradigm for patients with human immunodeficiency virus (HIV) has changed from managing an infectious condition with a suboptimal prognosis, to managing a long-term chronic disease. The wellness thermometer is a tool that was developed to assist with monitoring the biological, psychological, social and spiritual well-being of patients with HIV. Aim To evaluate the effectiveness of using the wellness thermometer in healthcare consultations with patients with HIV. Method This was a service evaluation that was undertaken in three UK HIV clinics in 2014...
June 7, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28582993/mapping-evidence-of-interventions-and-strategies-to-bridge-the-gap-in-the-implementation-of-the-prevention-of-mother-to-child-transmission-of-hiv-programme-policy-in-sub-saharan-countries-a-scoping-review
#11
Wilbroda H Ngidi, Joanne R Naidoo, Busisiwe P Ncama, Zamasomi P B Luvuno, Tivani P Mashamba-Thompson
BACKGROUND: Prevention of mother-to-child transmission (PMTCT) of HIV is a life-saving public health intervention. Sub-Saharan African (SSA) countries have made significant progress in the programme, but little is known about the strategies used by them to eliminate mother-to-child transmission of HIV. AIM: To map evidence of strategies and interventions employed by SSA in bridging the implementation gap in the rapidly changing PMTCT of HIV programme policy. METHODS: Electronic search of the databases MEDLINE, PubMed and SABINET for articles published in English between 2001 and August 2016...
May 29, 2017: African Journal of Primary Health Care & Family Medicine
https://www.readbyqxmd.com/read/28577690/value-of-comprehensive-hcv-treatment-among-vulnerable-high-risk-populations
#12
Gigi A Moreno, Alice Wang, Yuri Sánchez González, Oliver Díaz Espinosa, Diana K Vania, Brian R Edlin, Ronald Brookmeyer
OBJECTIVES: The objective of this study was to explore the trade-offs society and payers make when expanding treatment access to patients with chronic hepatitis C virus (HCV) infection in early stages of disease as well as to vulnerable, high-risk populations, such as people who inject drugs (PWID) and HIV-infected men who have sex with men (MSM-HIV). METHODS: A discrete time Markov model simulated HCV progression and treatment over 20 years. Population cohorts were defined by behaviors that influence the risk of HCV exposure: PWID, MSM-HIV, an overlap cohort of individuals who are both PWID and MSM-HIV, and all other adults...
June 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28574965/impact-of-comorbidity-and-ageing-on-health-related-quality-of-life-in-hiv-positive-and-hiv-negative-individuals
#13
Nienke Langebeek, Katherine W Kooij, Ferdinand W Wit, Ineke G Stolte, Mirjam A G Sprangers, Peter Reiss, Pythia T Nieuwkerk
BACKGROUND: HIV-infected individuals may be at risk for the premature onset of age-associated noncommunicable comorbidities. Being HIV-positive, having comorbidities and being of higher age may adversely impact health-related quality of life (HRQL). We investigated the possible contribution of HIV infection, comorbidities and age on HRQL and depression. METHODS: HIV-infected individuals and uninfected controls from the AGEhIV Cohort Study were screened for the presence of comorbidities...
June 19, 2017: AIDS
https://www.readbyqxmd.com/read/28570572/optimal-costs-of-hiv-pre-exposure-prophylaxis-for-men-who-have-sex-with-men
#14
Jennie McKenney, Anders Chen, Karen W Hoover, Jane Kelly, David Dowdy, Parastu Sharifi, Patrick S Sullivan, Eli S Rosenberg
INTRODUCTION: Men who have sex with men (MSM) are disproportionately affected by HIV due to their increased risk of infection. Oral pre-exposure prophylaxis (PrEP) is a highly effictive HIV-prevention strategy for MSM. Despite evidence of its effectiveness, PrEP uptake in the United States has been slow, in part due to its cost. As jurisdictions and health organizations begin to think about PrEP scale-up, the high cost to society needs to be understood. METHODS: We modified a previously-described decision-analysis model to estimate the cost per quality-adjusted life-year (QALY) gained, over a 1-year duration of PrEP intervention and lifetime time horizon...
2017: PloS One
https://www.readbyqxmd.com/read/28562539/false-positive-18fdg-pet-ct-results-due-to-exogenous-lipoid-pneumonia-secondary-to-oily-drug-inhalation-a-case-report
#15
David Chardin, Guillaume Nivaggioni, Philippe Viau, Caherine Butori, Bernard Padovani, Caroline Grangeaon, Micheline Razzouk-Cadet
RATIONALE: Exogenous lipoid pneumonia is a rare condition due to abnormal presence of oily substances in the lungs. It is a rarely known cause for false positive FDG PET-CT results and can sometimes lead to invasive investigations. Searching and finding the source of the oily substance is one of the keys to the diagnosis. Inhalation of oily drugs during snorting has rarely been described. PATIENT CONCERNS: A patient with well controlled HIV infection was referred for an FDG PET-CT to assess extension of Kaposi's disease, recently removed from his right foot...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28560631/genetics-of-hiv-associated-sensory-neuropathy-and-related-pain-in-africans
#16
REVIEW
Huguette Gaelle Ngassa Mbenda, Antonia Wadley, Zane Lombard, Catherine Cherry, Patricia Price, Peter Kamerman
Despite the use of safer antiretroviral medications, the rate of HIV-associated sensory neuropathy (HIV-SN), the most common neurological complication of HIV, remains high. This condition is often painful and has a negative effect on quality of life. Up to 90% of those with HIV-SN experience pain for which there is no effective analgesic treatment. Genetic factors are implicated, but there is a lack of a comprehensive body of research for African populations. This knowledge gap is even more pertinent as Africans are most affected by HIV...
May 30, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28560611/have-you-talked-about-it-advance-care-planning-among-african-americans-living-with-hiv-in-baltimore
#17
Allysha C Maragh-Bass, Yiqing Zhao, Sarina R Isenberg, Mary M Mitchell, Amy R Knowlton
Advance care planning (ACP) is the process of planning for when individuals are unable to make their own healthcare decisions. Research suggests ACP is understudied among HIV-positive African Americans. We explored ACP knowledge, preferences, and practices with HIV-positive African Americans from an urban HIV-specialty clinic (AFFIRM study). Participants completed surveys and interviews. Descriptive analyses and Poisson regression were conducted on survey data. Qualitative interviews were coded using grounded theory/constant comparative method...
May 30, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28558805/development-of-a-12-item-short-version-of-the-hiv-stigma-scale
#18
Maria Reinius, Lena Wettergren, Maria Wiklander, Veronica Svedhem, Anna Mia Ekström, Lars E Eriksson
BACKGROUND: Valid and reliable instruments for the measurement of enacted, anticipated and internalised stigma in people living with HIV are crucial for mapping trends in the prevalence of HIV-related stigma and tracking the effectiveness of stigma-reducing interventions. Although longer instruments exist, e.g., the commonly used 40-item HIV Stigma Scale by Berger et al., a shorter instrument would be preferable to facilitate the inclusion of HIV stigma in more and broader surveys. Therefore, the aim of this work was to develop a substantially shorter, but still valid, version of the HIV Stigma Scale...
May 30, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28552210/immune-reconstitution-inflammatory-syndrome-iris-what-pathologists-should-know
#19
REVIEW
Ann Marie Nelson, Yukari C Manabe, Sebastian B Lucas
Antiretroviral therapy has significantly improved the quality and length of life for those patients able to access effective and sustained treatment. The resulting restoration of the immune response is associated with a change in the clinical presentation of opportunistic infections, and the histologic reaction to pathogens. A complex combination of alterations in host response across the stages of HIV infection has been documented over the past 3 decades. The defects are seen in both acute and chronic phases of inflammation and involve innate and adaptive immunity...
April 26, 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28547996/predicting-health-related-quality-of-life-in-people-living-with-hiv-in-nepal-mental-health-disorders-and-substance-use-determinants
#20
Khem N Pokhrel, Vidya D Sharma, Akira Shibanuma, Kalpana G Pokhrel, Linda B Mlunde, Masamine Jimba
HIV-positive people often experience mental health disorders and engage in substance use. Such conditions tend to impair their health-related quality of life (QOL). Evidence, however, is limited about the influence of mental health disorders and substance use on QOL by gender. Also, little is known about the influences of anxiety and high levels of stress on QOL. We recruited 682 HIV-positive people in Nepal and measured their depression, anxiety, stress levels, substance use, and QOL. Multiple linear regressions assessed the association of mental health disorders and substance use with QOL...
May 26, 2017: AIDS Care
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