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HIV and Quality of Life

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https://www.readbyqxmd.com/read/28213577/economic-evaluation-of-universal-prenatal-hiv-screening-compared-with-current-at-risk-policy-in-a-very-low-prevalence-country
#1
Michal Chowers, Oren Shavit
OBJECTIVES: Our objective was to economically evaluate universal HIV prenatal screening in Israel, a very low prevalence country (0.1%), compared with the current policy of testing only women belonging to high-risk (HR) groups. DESIGN: A cost-effectiveness analytical model was constructed. Life expectancies, direct medical costs and utility weights of an HIV-positive newborn and a healthy newborn were derived from the literature. Screening was assessed using fourth-generation combo tests...
March 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28209209/perceived-quality-of-life-among-visceral-leishmaniasis-and-hiv-coinfected-migrant-male-workers-in-northwest-ethiopia-a-qualitative-study
#2
Mekuriaw Alemayehu, Mamo Wubshet, Nebiyu Mesfin, Abebaw Gebayehu
BACKGROUND: There is paucity of data on quality of life as a dimension of treatment outcome among Visceral Leishmaniasis and HIV coinfected patients. This study sought to explore perceived quality of life among Visceral Leishmaniasis and HIV coinfected male migrant workers in Northwest Ethiopia. METHODS: Twenty Visceral Leishmaniasis and HIV coinfected study participants took part in the in-depth interviews at Visceral Leishmaniasis and HIV treatment centers. Ten participants were on antiretroviral treatment (ART) and the remaining 10 have not yet started ART...
February 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28207902/methamphetamine-treatment-outcomes-among-gay-men-attending-a-lgbti-specific-treatment-service-in-sydney-australia
#3
Toby Lea, Johann Kolstee, Sarah Lambert, Ross Ness, Siobhan Hannan, Martin Holt
Gay and bisexual men (GBM) report higher rates of methamphetamine use compared to heterosexual men, and thus have a heightened risk of developing problems from their use. We examined treatment outcomes among GBM clients receiving outpatient counseling at a lesbian, gay, bisexual, transgender and intersex (LGBTI)-specific, harm reduction treatment service in Sydney, Australia. GBM receiving treatment for methamphetamine use from ACON's Substance Support Service between 2012-15 (n = 101) were interviewed at treatment commencement, and after 4 sessions (n = 60; follow-up 1) and 8 sessions (n = 32; follow-up 2)...
2017: PloS One
https://www.readbyqxmd.com/read/28207516/economic-evaluation-of-mobile-phone-text-message-interventions-to-improve-adherence-to-hiv-therapy-in-kenya
#4
Anik R Patel, Jason Kessler, R Scott Braithwaite, Kimberly A Nucifora, Harsha Thirumurthy, Qinlian Zhou, Richard T Lester, Carlo A Marra
BACKGROUND: A surge in mobile phone availability has fueled low cost short messaging service (SMS) adherence interventions. Multiple systematic reviews have concluded that some SMS-based interventions are effective at improving antiretroviral therapy (ART) adherence, and they are hypothesized to improve retention in care. The objective of this study was to evaluate the cost-effectiveness of SMS-based adherence interventions and explore the added value of retention benefits. METHODS: We evaluated the cost-effectiveness of weekly SMS interventions compared to standard care among HIV+ individuals initiating ART for the first time in Kenya...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28199405/co-financing-for-viral-load-monitoring-during-the-course-of-antiretroviral-therapy-among-patients-with-hiv-aids-in-vietnam-a-contingent-valuation-survey
#5
Quyen Le Thi Nguyen, Long Hoang Nguyen, Bach Xuan Tran, Huong Thi Thu Phan, Huong Thi Le, Hinh Duc Nguyen, Tho Dinh Tran, Cuong Duy Do, Cuong Manh Nguyen, Vu Thi Minh Thuc, Carl Latkin, Melvyn W B Zhang, Roger C M Ho
BACKGROUND: Viral load testing is considered the gold standard for monitoring HIV treatment; however, given its high cost, some patients cannot afford viral load testing if this testing is not subsidized. Since foreign aid for HIV/AIDS in Vietnam is rapidly decreasing, we sought to assess willingness to pay (WTP) for viral load and CD4 cell count tests among HIV-positive patients, and identified factors that might inform future co-payment schemes. METHODS: A multi-site cross-sectional survey was conducted with 1133 HIV-positive patients on antiretroviral therapy (ART) in Hanoi and Nam Dinh...
2017: PloS One
https://www.readbyqxmd.com/read/28188030/unveiling-of-hiv-dynamics-among-transgender-women-a-respondent-driven-sampling-study-in-rio-de-janeiro-brazil
#6
Beatriz Grinsztejn, Emilia M Jalil, Laylla Monteiro, Luciane Velasque, Ronaldo I Moreira, Ana Cristina F Garcia, Cristiane V Castro, Alícia Krüger, Paula M Luz, Albert Y Liu, Willi McFarland, Susan Buchbinder, Valdilea G Veloso, Erin C Wilson
BACKGROUND: The burden of HIV in transgender women (transwomen) in Brazil remains unknown. We aimed to estimate HIV prevalence among transwomen in Rio de Janeiro and to identify predictors of newly diagnosed HIV infections. METHODS: We recruited transwomen from Rio de Janeiro, Brazil, by respondent-driven sampling. Eligibility criteria were self-identification as transwomen, being 18 years of age or older, living in Rio de Janeiro or its metropolitan area, and having a valid peer recruitment coupon...
February 7, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28187740/multi-year-school-based-implementation-and-student-outcomes-of-an-evidence-based-risk-reduction-intervention
#7
Bo Wang, Bonita Stanton, Lynette Deveaux, Sonja Lunn, Glenda Rolle, Richard Adderley, Maxwell Poitier, Veronica Koci, Sharon Marshall, Perry Gomez
BACKGROUND: Intervention effects observed in efficacy trials are rarely replicated when the interventions are broadly disseminated, underscoring the need for more information about factors influencing real-life implementation and program impact. Using data from the ongoing national implementation of an evidence-based HIV prevention program [Focus on Youth in The Caribbean (FOYC)] in The Bahamas, this study examines factors influencing teachers' patterns of implementation, the impact of teachers' initial implementation of FOYC, and subsequent delivery of the booster sessions on students' outcomes...
February 10, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28177965/gastrointestinal-symptom-distress-is-associated-with-worse-mental-and-physical-health-related-quality-of-life
#8
Tyler J O'neill, Janet M Raboud, Jill Tinmouth, Sean B Rourke, Sergio Rueda, Trevor A Hart, Curtis Cooper, Anita Rachlis, Ann N Burchell
BACKGROUND: The prevalence of self-reported GI symptoms and distress is high, but few studies have quantified their impact on HRQOL. METHODS: We conducted a prospective cohort study of HIV patients in care in Ontario, Canada (2007-2014). General linear mixed models were used to assess the impact of GI symptoms (diarrhea/soft stool, nausea/vomiting, bloating/painful abdomen, loss of appetite, weight loss/wasting) and distress (range: 0 to 4) on physical and mental HRQOL summary scores (range: 0 to 100) measured by the Medical Outcomes Survey SF-36...
February 7, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28176538/intimate-partner-violence-depression-and-quality-of-life-among-women-living-with-hiv-aids-in-a-coastal-city-of-south-india
#9
Basavaprabhu Achchappa, Mahak Bhandary, Bhaskaran Unnikrishnan, John T Ramapuram, Vaman Kulkarni, Satish Rao, Deepak Maadi, Anish Bhat, Shivani Priyadarshni
BACKGROUND: Intimate partner violence (IPV) is a severe form of abuse prevalent in urban and rural areas of India with its effects on mental and physical health of the person receiving it, leading to a poorer quality of life. METHODS: A cross-sectional study was conducted among 99 women living with HIV, and information was collected using abuse assessment scale. The data were entered and analyzed using SPSS version 17.0. RESULTS: The IPV was reported by 19...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28170303/trends-and-correlates-of-cigarette-smoking-and-its-impacts-on-health-related-quality-of-life-among-people-living-with-hiv-findings-from-the-ontario-hiv-treatment-network-cohort-study-2008-2014
#10
Tsegaye Bekele, Sergio Rueda, Sandra Gardner, Janet Raboud, Marek Smieja, Richard Kennedy, David Fletcher, Ann N Burchell, Jean Bacon, Sean B Rourke
We sought to examine the trends of cigarette smoking, identify correlates of smoking, and examine the impacts of smoking on health-related quality of life (HRQOL) among people living with HIV in Ontario, Canada. Study sample included 4473 individuals receiving care and enrolled in the Ontario HIV Treatment Network Cohort Study. Self-report data on cigarette smoking, HRQOL, and demographic and sociobehavioral variables were collected between 2008 and 2014 through annual face-to-face interviews. Clinical data were abstracted from participants' medical records and enhanced through linkage with a provincial public health laboratory database...
February 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28155799/-development-of-valorization-of-physical-activity-the-role-of-hiv-associations
#11
Estelle Duval, Sylvain Férez, Julie Thomas, Laura Schuft
<ce:para>With the arrival of triple combination therapy in 1996-1997, HIV infection, considered up until then to be a life-threatening condition, changed statuses within the realm of public health actions Progressively likened to a “chronic illness”, the discourse on HIV prevention targeting people living with HIV (PLHIV) began to evolve. A review of the scientific literature and the journals of four national HIV associations published between 1990 and 2010 shows that physical activities, previously discouraged because considered to be dangerous, have become increasingly presented as a means of improving quality of life and are increasingly recommended for PLHIV...
June 8, 2016: Santé Publique: Revue Multidisciplinaire Pour la Recherche et L'action
https://www.readbyqxmd.com/read/28152666/provision-of-critical-care-services-to-hiv-infected-children-in-an-era-of-advanced-intensive-care-and-availability-of-combined-antiretroviral-therapy
#12
Prakash M Jeena, Miriam Adhikari
Intensive care facilities are always in demand in the public sector and there is constant competition for beds. Appropriate allocation of children to these resources is based on the ethical principles of distributive justice and beneficence that is determined on the presumed short-term outcome of the acute illness, long-term outcome of the underlying chronic disease and the overall demand for these facilities. At the onset of the HIV epidemic in South Africa, HIV-infected children were refused admission to the paediatric intensive care unit (PICU) on the basis of poor ICU outcomes and the lack of provision of combined antiretroviral therapy (cART) for survivors...
February 3, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28150510/quality-of-life-in-an-italian-cohort-of-people-living-with-hiv-in-the-era-of-combined-antiretroviral-therapy-evidence-from-i-a-n-u-a-study-investigation-on-antiretroviral-therapy
#13
A Venturini, G Cenderello, A Di Biagio, B Giannini, M Ameri, M Giacomini, M Montefiori, M Setti, G Mazzarello, C Merlano, P Orcamo, C Viscoli, G Cassola
The aims of this study were to assess the Health Related Quality of Life (HRQoL) of People Living with HIV/AIDS (PLWHA) who attend outpatient services in Genoa, Italy, and to evaluate the relationship between HRQoL and clinical factors, primarily: CD4+ cell count, viral load and HIV-Hepatitis C Virus (HCV) coinfection. A cross-sectional study was performed involving a sample of 943 consecutive patients. Firstly the EuroQol-Five Dimensions-Three Level (EQ-5D-3L) self-reported questionnaire was used to evaluate HRQoL, while socio-demographic information was collected using a separate self-administered questionnaire...
February 2, 2017: AIDS Care
https://www.readbyqxmd.com/read/28132701/a-randomized-study-of-the-use-of-screening-brief-intervention-and-referral-to-treatment-sbirt-for-drug-and-alcohol-use-with-jail-inmates
#14
Michael L Prendergast, Kathryn McCollister, Umme Warda
BACKGROUND: Screening, brief intervention, and referral to treatment (SBIRT) is an evidence-based practice that has been shown to reduce alcohol and drug use in healthcare, educational, and other settings, but research on the effectiveness of SBIRT with populations involved in the criminal justice system is limited. These populations have high rates of substance use but have limited access to interventions. METHODS: The study randomized 732 jail inmates from a large urban jail to the SBIRT intervention or to the control group...
March 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28130990/psychiatric-symptoms-quality-of-life-and-hiv-status-among-people-using-opioids-in-saint-petersburg-russia
#15
Alethea Desrosiers, Elena Blokhina, Evgeny Krupitsky, Edwin Zvartau, Richard Schottenfeld, Marek Chawarski
BACKGROUND: The Russian Federation is experiencing a very high rate of HIV infection among people who inject drugs (PWID). However, few studies have explored characteristics of people with co-occurring opioid use disorders and HIV, including psychiatric symptom presentations and how these symptoms might relate to quality of life. The current study therefore explored a.) differences in baseline psychiatric symptoms among HIV+ and HIV- individuals with opioid use disorder seeking naltrexone treatment at two treatment centers in Saint Petersburg, Russia and b...
January 23, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28129756/a-cluster-randomised-controlled-trial-protocol-of-an-adapted-intervention-for-alcohol-use-disorders-in-people-living-with-hiv-and-aids-impact-on-alcohol-use-general-functional-ability-quality-of-life-and-adherence-to-haart
#16
Munyaradzi Madhombiro, Bazondlile Dube-Marimbe, Michelle Dube, Dixon Chibanda, Moleen Zunza, Simbarashe Rusakaniko, David Stewart, Soraya Seedat
BACKGROUND: Interventions for alcohol use disorders (AUDs) in HIV infected individuals have been primarily targeted at HIV risk reduction and improved antiretroviral treatment adherence. However, reduction in alcohol use is an important goal. Alcohol use affects other key factors that may influence treatment course and outcome. In this study the authors aim to administer an adapted intervention for AUDs to reduce alcohol use in people living with HIV/AIDS (PLWHA). METHODS: This study is a cluster randomised controlled trial at 16 HIV care clinics...
January 28, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28125951/quality-of-life-improvement-in-hiv-1-patients-treated-with-raltegravir-in-a-real-life-observational-study-racing
#17
Bruno Spire, Lella Nait-Ighil, Pascal Pugliese, Isabelle Poizot-Martin, Vincent Jullien, Anne-Geneviève Marcelin, Eric Billaud
BACKGROUND: Good efficacy and safety of raltegravir in person living with HIV was demonstrated in clinical trials over five years, but real-life data, particularly about quality of life (QoL), are lacking. QoL was evaluated over time in adult patients first treated or switched to regimens containing raltegravir in an observational cohort study. METHODS: Patient QoL was evaluated using the Fatigue Impact Scale (FIS) and the HIV Symptom Index (HSI). Data were collected at baseline and at 1, 3, 6, 12, 18, and 24 months...
January 2017: HIV Clinical Trials
https://www.readbyqxmd.com/read/28121710/improved-quality-of-life-with-immediate-initiation-of-antiretroviral-therapy-in-the-strategic-timing-of-antiretroviral-therapy-trial
#18
Alan R Lifson, Birgit Grund, Edward M Gardner, Richard Kaplan, Eileen Denning, Nicole Engen, Catherine L Carey, Fabian Chen, Sounkalo Dao, Eric Florence, Jesus Sanz, Sean Emery
OBJECTIVE: To determine if immediate compared to deferred initiation of antiretroviral therapy (ART) in healthy persons living with HIV (PLWH) had a more favorable impact on health-related quality of life (QOL), or self-assessed physical, mental and overall health status. DESIGN: QOL was measured in START (Strategic Timing of Antiretroviral Therapy), which randomized healthy ART naive PLWH with >500 CD4+ cells/μl from 35 countries to immediate versus deferred ART...
January 24, 2017: AIDS
https://www.readbyqxmd.com/read/28117537/persistent-neuropsychiatric-impairment-in-hcv-patients-despite-clearance-of-the-virus
#19
M Dirks, H Pflugrad, K Haag, H L Tillmann, H Wedemeyer, D Arvanitis, H Hecker, A Tountopoulou, A Goldbecker, H Worthmann, K Weissenborn
One of the most disabling symptoms of hepatitis C virus (HCV) infection is chronic fatigue. While this is accepted for HCV polymerase chain reaction (PCR)-positive patients, a relationship between HCV infection and chronic fatigue is questioned after successful virus eradication. As fatigue is a subjective criterion, we aimed to evaluate in addition mood alterations and cognitive function in HCV-exposed patients with only mild liver disease and to assess a) possible interrelationships between these factors and health-related quality of life and b) the impact of viremia and former interferon treatment...
January 24, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/28116101/prevalence-of-anemia-in-renal-insufficiency-among-hiv-infected-patients-initiating-art-at-a-hospital-in-northeast-ethiopia
#20
Temesgen Fiseha, Zemenu Tamir, Abdurahaman Seid, Wondmagegn Demsiss
BACKGROUND: Anemia is a strong predictor of mortality and poor quality of life among persons with either renal impairment or HIV infection. In this study, we investigated the prevalence of anemia and its association with renal insufficiency among HIV infected patients initiating ART at a hospital in Northeast Ethiopia. METHODS: In this retrospective cohort study, records of 373 patients on ART were selected in Dessie Referral hospital, South Wollo, Northeast Ethiopia from September 2010 to August 2013...
2017: BMC Hematology
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