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HIV and Quality of Life

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https://www.readbyqxmd.com/read/29151199/loneliness-in-older-adults-living-with-hiv
#1
Meredith Greene, Nancy A Hessol, Carla Perissinotto, Roland Zepf, Amanda Hutton Parrott, Cameron Foreman, Robert Whirry, Monica Gandhi, Malcolm John
We conducted a cross-sectional study among HIV-positive adults age ≥ 50 in San Francisco to evaluate the frequency of loneliness, characteristics of those who reported loneliness, and the association of loneliness with functional impairment and health-related quality of life (HRQoL). Participants (N = 356) were predominately male (85%); 57% were white; median age was 56. 58% reported any loneliness symptoms with 24% reporting mild, 22% moderate and 12% severe loneliness. Lonely participants were more likely to report depression, alcohol and tobacco use, and have fewer relationships...
November 18, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29141645/measuring-quality-of-life-among-people-living-with-hiv-a-systematic-review-of-reviews
#2
REVIEW
Vanessa Cooper, Jane Clatworthy, Richard Harding, Jennifer Whetham
AIM: A systematic review of reviews was conducted to identify and appraise brief measures of health-related quality of life (HRQoL) that have been used in peer-reviewed research with people living with HIV. METHODS: The review was conducted in two stages: 1) search of electronic databases to identify systematic reviews of tools used to measure HRQoL in adults living with HIV, published since the year 2000; 2) selection of HRQol scales from those identified in the reviews...
November 15, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29141626/health-related-quality-of-life-of-hiv-aids-patients-on-highly-active-anti-retroviral-therapy-at-a-university-referral-hospital-in-ethiopia
#3
Abdrrahman Shemsu Surur, Fitsum Sebsibe Teni, Wondwessen Wale, Yihenew Ayalew, Betel Tesfaye
BACKGROUND: Highly active antiretroviral therapy improves the longevity of patients living with HIV/AIDS. We conducted the study in order to assess health related quality of life of HIV/AIDS patients and the association of socio-demographic and disease related variables with health related quality of life. METHODS: Health facility based cross-sectional study among 400 HIV/AIDS patients taking highly active anti-retroviral therapy from Gondar University referral hospital was conducted...
November 15, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29136117/cost-effectiveness-of-community-based-hiv-self-testing-in-blantyre-malawi
#4
Hendramoorthy Maheswaran, Aileen Clarke, Peter MacPherson, Felistas Kumwenda, David G Lalloo, Elizabeth L Corbett, Stavros Petrou
Background: HIV self-testing (HIVST) is effective, with scale-up underway in sub-Saharan Africa. We assessed cost-effectiveness of adding HIVST to existing facility-based HIV testing and counselling (HTC) services. Both 2010 (initiate at CD4<350 cells/μl) and 2015 (initiate all) WHO guidelines for antiretroviral treatment (ART) were considered. Methods: A microsimulation model was developed that evaluated cost-effectiveness, from both health provider and societal perspectives, of an HIVST service implemented in a cluster-randomised trial (CRT) (ISRCTN02004005) in Malawi...
November 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29135895/-comparing-efficacy-and-costs-of-four-facial-fillers-in-hiv-associated-lipodystrophy-a-clinical-trial
#5
Alfonso Vallejo, Angela A Garcia-Ruano, Carmen Pinilla, Michele Castellano, Esther Deleyto, Rosa Perez-Cano
BACKGROUND: The objective was to evaluate and compare safety and effectiveness of four different dermal fillers in the treatment of facial lipoatrophy secondary to Human Immunodeficiency Virus (HIV). METHODS: We conducted a clinical trial including 147 patients suffering from HIV-induced lipoatrophy treated with Sculptra® (poly-L-lactic acid), Radiesse® (calcium hydroxylapatite), Aquamid® (polyacrylamide) or autologous fat. Objective and subjective changes were evaluated during a 24-monthfollow-up...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29135654/cost-effectiveness-of-peer-versus-venue-based-approaches-for-detecting-undiagnosed-hiv-among-heterosexuals-in-high-risk-new-york-city-neighborhoods
#6
Elizabeth R Stevens, Kimberly Nucifora, Qinlian Zhou, R Scott Braithwaite, Charles M Cleland, Amanda S Ritchie, Alexandra H Kutnick, Marya V Gwadz
INTRODUCTION: We used a computer simulation of HIV progression and transmission to evaluate the cost-effectiveness of a scale-up of three strategies to seek out and test individuals with undiagnosed HIV in New York City (NYC). SETTING: Hypothetical NYC population METHODS:: We incorporated the observed effects and costs of the three "seek and test" strategies in a computer simulation of HIV in NYC, comparing a scenario in which the strategies were scaled up with a one-year implementation or a long-term implementation with a counterfactual scenario with no scale-up...
November 6, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29131849/modelling-the-cost-effectiveness-of-hiv-care-shows-a-clear-benefit-when-transmission-risk-is-considered-in-the-calculations-a-message-for-central-and-eastern-europe
#7
Justyna D Kowalska, Grzegorz Wójcik, Jakub Rutkowski, Magdalena Ankiersztejn-Bartczak, Ewa Siewaszewicz
BACKGROUND: HIV epidemic remains a major global health issue. Data from cost-effectiveness analyses base on CD4+ count and morbidity in patients with symptomatic and asymptomatic HIV infection. The approach adopted in these analyses includes many other factors, previously not investigated. Additionally, we evaluate the impact of sexual HIV transmission due to delayed cART on the cost-effectiveness of care. METHODS: A lifetime Markov model (1-month cycle) was developed to estimate the cost per quality adjusted life years (QALY) for a 1- and 3-year delay in starting cART (as compared to starting immediately at linkage to care) lifetime costs, clinical outcomes and cost-effectiveness...
2017: PloS One
https://www.readbyqxmd.com/read/29122428/complex-problems-care-demands-and-quality-of-life-among-people-living-with-hiv-in-the-antiretroviral-era-in-indonesia
#8
Linlin Lindayani, Yen-Chin Chen, Jung-Der Wang, Nai-Ying Ko
People living with HIV (PLWH) suffer from physical and psychological distress that palliative care could alleviate. Our cross-sectional study identified HIV-related problems and demands for palliative care at different disease stages, and their interactions with quality of life (QOL) in 215 PLWH from a referral hospital and an AIDS nongovernmental organization in Indonesia. A brief survey of demographic information, the Bahasa version of Problems and Needs of Palliative Care, and the World Health Organization Quality of Live in HIV-infected Persons instrument (WHOQOL-HIV BREF; Cronbach's alpha = ...
October 10, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29120307/preliminary-investigation-of-the-stbbi-stigma-scale-description-and-pilot-results
#9
Anne C Wagner, Rachel MacLean
OBJECTIVES: Sexually transmitted and blood-borne infections (STBBIs) are associated with stigmatizing attitudes and beliefs, which can affect the quality of and access to health care, as well as mental health and quality of life. The current study describes the adaptation from an HIV-related stigma scale and pilot testing of a new STBBI Stigma Scale, assessing the stigmatizing attitudes and beliefs of health and social service providers in Canada. METHODS: 144 health and social service providers from across Canada completed the newly adapted scale assessing stigma associated with HIV, hepatitis C, other viral STBBIs and bacterial STBBIs, as well as demographic information, a scale of social desirability and measures of convergent and divergent validity...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29116878/evaluation-of-methadone-treatment-in-malaysia-findings-from-the-malaysian-methadone-treatment-outcome-study-mytos
#10
Norsiah Ali, Salina Abd Aziz, Salmah Nordin, Norliza Che Mi, Norni Abdullah, V Paranthaman, Maimunah Mahmud, Anne Yee, Mahmoud Danaee
BACKGROUND: Opioid misuse and dependence is a global issue with a huge negative impact. In Malaysia, heroin is still the main illicit drug used, and methadone maintenance treatment (MMT) has been used since 2005. OBJECTIVE: To evaluate the effectiveness of MMT. METHODS: This was a cross-sectional study conducted in 103 treatment centers between October and December 2014 using a set of standard questionnaires. Data were analyzed using SPSS Statistics 20...
November 8, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29115159/independent-and-synergistic-effects-of-self-and-public-stigmas-on-quality-of-life-of-hiv-infected-persons
#11
Linlin Lindayani, Kusman Ibrahim, Jung-Der Wang, Nai-Ying Ko
Stigma has a potential impact on the quality of life of HIV-infected individuals over time. There is little empirical evidence regarding the first appearance and dynamic changes among different types of stigma, self-stigma and public-stigma, and their impacts on quality of life over time in HIV-infected persons. The purpose of this study was to assess the dynamic changes in self-stigma and public-stigma along the time course and determined their independent and synergistic impacts on quality of life. A Cross-sectional study was conducted at Two HIV-designed hospitals and two branches of non-government an-AIDS organizations in Wes Java, Indonesia...
November 8, 2017: AIDS Care
https://www.readbyqxmd.com/read/29112062/health-related-quality-of-life-of-people-with-hiv-an-assessment-of-patient-related-factors-and-comparison-with-other-chronic-diseasess
#12
Esther A N Engelhard, Colette Smit, Peter R Van Dijk, T Martijn Kuijper, Paulien R Wermelingg, Angelique Eam Weel, Michiel R de Boer, Kees Brinkman, Suzanne E Geerlings, Pythia T Nieuwkerk
OBJECTIVES: The health-related quality of life (HRQOL) of people with HIV is lower than in the general population, but it is unknown how it compares to that of persons with other chronic medical conditions. We compared HRQOL in HIV with HRQOL in diabetes mellitus (DM) type 1, DM type 2 and rheumatoid arthritis (RA). Additionally, we investigated factors associated with HRQOL in HIV. DESIGN: cross-sectional study METHODS:: HRQOL was measured with the Medical Outcomes Study Short Form 36-item health survey (SF-36) in a nationwide sample of people with HIV in care in the Netherlands and on cART ≥ 6 months...
November 2, 2017: AIDS
https://www.readbyqxmd.com/read/29095883/patterns-of-patient-and-healthcare-provider-viewpoints-regarding-participation-in-hiv-cure-related-clinical-trials-findings-from-a-multicentre-french-survey-using-q-methodology-anrs-apsec
#13
Christel Protière, Bruno Spire, Marion Mora, Isabelle Poizot-Martin, Marie Préau, Marjolaine Doumergue, Philippe Morlat, David Zucman, Cécile Goujard, François Raffi, Olivier Lambotte, Marie Suzan-Monti
CONTEXT: Despite huge advances in the fight against HIV concerning diagnosis, clinical efficacy of antiretroviral treatments (ART), patient survival and quality of life, there is still no cure. Recent developments in HIV cure research have opened the way for clinical trials which could lead to a temporary or definitive end to ART. However, ethical questions exist about related trial-participation risks. The main goal of the ANRS-APSEC survey was, using Q-methodology, to investigate the viewpoints of people living with HIV (PLWH) and HIV healthcare providers (HHP) regarding motivations for and barriers to participation in HIV Cure-related clinical trials (HCRCT)...
2017: PloS One
https://www.readbyqxmd.com/read/29095018/nutritional-status-and-quality-of-life-in-hiv-infected-patients
#14
Barbara Fernandes De Carvalho, Sara Policarpo, Ana Catarina Moreira
INTRODUCTION: Nutritional status and the progression of the human immunodeficiency virus (HIV) are interlinked; though some studies have looked at the impact nutritional status has on quality of life (QoL) in patients with chronic diseases, few have studied this in HIV-infected individuals. OBJECTIVE: To investigate the relationship between nutritional status and QoL in adults with a recent HIV diagnosis. METHODS: Individuals with an HIV diagnosis performed in the fourteen months prior to a medical visit to one of Lisbon's central hospitals were eligible...
July 28, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29080856/formulation-and-evaluation-of-selected-transmucosal-dosage-forms-containing-a-double-fixed-dose-of-acyclovir-and-ketoconazole
#15
Joe M Viljoen, Danélia Botes, Jan H Steenekamp
Viral and fungal dermatological manifestations are often the first and only sign of HIV/AIDS. They are cosmetically disfiguring and threaten the quality of life, but can be treated by acyclovir and ketoconazole, correspondingly. This study attempted the formulation of stable, double fixed-dose acyclovir and ketoconazole novel transmucosal dosage forms, which are able to provide an efficient flux for both compounds. A cream, gel and lip balm formulation containing both drugs were formulated that can be applied to mucosal tissue...
November 1, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29080244/impaired-patient-reported-outcomes-persist-in-hiv-hcv-co-infected-patients-and-in-cirrhotic-patients-despite-hcv-clearance
#16
Fabienne Marcellin, Philippe Morlat, Linda Wittkop, Dominique Salmon-Ceron, Maria Patrizia Carrieri
Dirks et al.(1) 's recent study provides greater insight into the neuropsychiatric symptoms experienced by HCV infected patients and questions how these symptoms are associated with HCV clearance. The authors show that in HCV infected patients with mild liver disease, none of the following outcomes depend on HCV clearance: cognitive function, mood alteration, health-related quality of life (HRQL) and fatigue (FIS scores). However, these results may not be generalizable to HIV-HCV co-infected patients and cirrhotic patients, who were excluded from the study and who are generally more concerned by fatigue and neuropsychiatric symptoms...
October 27, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29076676/adrenal-insufficiency-in-pakistani-hiv-infected-patients
#17
Bahjat Afreen, Khurshid Ahmed Khan, Amna Riaz
BACKGROUND: Adrenal insufficiency (AI) is the most common endocrine complication among patients with AIDS/HIV infection and there are number of causes of AI in HIV patients. Human immunodeficiency virus directly as well as indirectly destroys adrenal glands. The estimates of its prevalence and severity vary. AI is the most life threatening but readily correctable endocrine complication that occurs in persons with HIV infection. This study was carried out to determine the frequency of Adrenal Insufficiency in HIV patients and their clinical features as proper diagnosis and timely treatment have been shown to improve quality of life and long-term mortality in AIDS patients...
July 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/29076059/impact-of-care-at-foster-homes-on-the-health-related-quality-of-life-of-hiv-infected-children-and-adolescents-a-cross-sectional-study-from-india
#18
K G Gopakumar, Kamalakshi G Bhat, Shantharam Baliga, Nitin Joseph, Neha Mohan, Avinash K Shetty
PURPOSE: To assess the impact of care at foster homes on the health-related quality of life (HRQOL) of children living with HIV (CLHIV), attending a referral ART Centre, and to compare their HRQOL with children living in their own homes. METHODS: A cross-sectional study was conducted in 144 CLHIV between 5 and 18 years of age, attending a referral ART Centre in South India to assess their HRQOL using the standard PedsQL™ 4.0 questionnaire. Data were then analysed to compare the HRQOL of children living in foster homes to those children living in their own homes...
October 26, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29075105/patient-preferences-for-antiretroviral-therapy-effectiveness-quality-of-life-access-and-novel-delivery-methods
#19
Ellen F Eaton, Chastity McDavid, Mary Katy Banasiewicz, Michael J Mugavero, Sara J Knight
OBJECTIVE: The objective of this study was to understand patient preferences for contemporary antiretroviral therapy (ART) by focusing on three areas that have been understudied: minority patients (racial/ethnic and sexual minorities), experience with novel single-tablet regimens made available in the last 10 years, and patient concerns related to ART. The rationale was that identifying ART characteristics that are most desirable could inform provider prescribing practices, increase the use of patient-centered ART, maximize durability and ART adherence, and ultimately improve HIV outcomes, such as viral suppression and AIDS-related comorbidities...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29069922/resources-to-cope-with-stigma-related-to-hiv-status-gender-identity-and-sexual-orientation-in-gay-men-and-transgender-women
#20
Inés Arístegui, Pablo D Radusky, Virginia Zalazar, Mar Lucas, Omar Sued
The stigma related to HIV status, gender identity, and sexual orientation has negative implications for the quality of life of individuals. A qualitative study was conducted to explore the resources that these stigmatized groups recognize as tools to cope with stigma and maintain their psychological well-being. Four focus groups were conducted with gay men and transgender women divided by HIV status. A thematic analysis revealed that individual, interpersonal, and institutional resources are commonly recognized as coping resources...
October 1, 2017: Journal of Health Psychology
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