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HIV and Quality of Life

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https://www.readbyqxmd.com/read/28344518/hypogonadism-in-the-hiv-infected-man
#1
REVIEW
Nicholas Wong, Miles Levy, Iain Stephenson
Low testosterone levels are frequently observed among men with treated and untreated HIV infection. However, the interpretations of biochemical measurements of testicular function are challenging and need to be considered in the context of the clinical presentation and scenario. The distinction between primary and secondary hypogonadism and determination of the underlying clinical pathophysiology are not always straightforward. Early recognition of clinical hypogonadism and appropriate treatment may improve clinical outcomes and quality of life for affected individuals...
2017: Current Treatment Options in Infectious Diseases
https://www.readbyqxmd.com/read/28343351/health-related-quality-of-life-hrqol-and-its-correlates-among-community-recruited-children-living-with-hiv-and-uninfected-children-born-to-hiv-infected-parents-in-west-bengal-india
#2
Aritra Das, Roger Detels, Abdelmonem A Afifi, Marjan Javanbakht, Frank J Sorvillo, Samiran Panda
PURPOSE: Helping children living with HIV (CLH) to attain an optimum quality of life is an important goal for HIV programs around the world. Our principal objectives were to determine the association of HIV infection with different domains of health-related quality of life (HRQoL) among 8- to 15-year-old CLH in India and to compare the HRQoL parameters between CLH and HIV-negative children born to HIV-infected parents ("HIV-affected"). We also assessed whether antiretroviral therapy (ART) and CD4 lymphocyte counts were associated with HRQoL among CLH...
March 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28343331/economic-and-public-health-consequences-of-delayed-access-to-medical-care-for-migrants-living-with-hiv-in-france
#3
Marlène Guillon, Michel Celse, Pierre-Yves Geoffard
In 2013, migrants accounted for 46% of newly diagnosed cases of HIV (human immunodeficiency virus) infection in France. These populations meet with specific obstacles leading to late diagnosis and access to medical care. Delayed access to care (ATC) for HIV-infected migrants reduces their life expectancy and quality of life. Given the reduction of infectivity under antiretroviral (ARV) treatment, delayed ATC for HIV-infected migrants may also hinder the control of the HIV epidemic. The objective of this study is to measure the public health and economic consequences of delayed ATC for migrants living with HIV in France...
March 25, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28329208/differentiated-hiv-rna-viral-load-monitoring-in-resource-limited-settings-an-economic-analysis
#4
Diana M Negoescu, Zhenhuan Zhang, Heiner C Bucher, Eran Bendavid
Background: Viral load (VL) monitoring for patients receiving antiretroviral therapy (ART) is recommended worldwide. However, the costs of frequent monitoring are a barrier to implementation in resource-limited settings. The extent to which personalized monitoring frequencies may be cost-effective is unknown. Methods: We created a simulation model parameterized using person-level longitudinal data to assess the benefits of flexible monitoring frequencies. Our data-driven model tracked HIV+ individuals for 10 years following ART initiation...
March 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28328545/economic-costs-and-health-related-quality-of-life-outcomes-of-hiv-treatment-following-self-and-facility-based-hiv-testing-in-a-cluster-randomised-trial
#5
Hendramoorthy Maheswaran, Stavros Petrou, Peter MacPherson, Felistas Kumwenda, David G Lalloo, Elizabeth L Corbett, Aileen Clarke
BACKGROUND: HIV self-testing (HIVST) is recommended in Africa, but little is known about how this approach influences economic outcomes following subsequent antiretroviral treatment (ART) compared to facility-based HIV testing and counselling (HTC). METHODS: HIV-positive participants attending HIV clinics, diagnosed by HIVST or facility-based HTC as part of a community cluster-randomised trial (ISRCTN02004005), were followed from initial assessment for ART until one-year postinitiation...
March 21, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28326285/impact-of-telemonitoring-approaches-on-integrated-hiv-and-tb-diagnosis-and-treatment-interventions-in-sub-saharan-africa-a-scoping-review
#6
REVIEW
Clarence S Yah, Ernest Tambo, Christopher Khayeka-Wandabwa, Jeanne Y Ngogang
Background: This paper explores telemonitoring/mhealth approaches as a promising real time and contextual strategy in overhauling HIV and TB interventions quality access and uptake, retention,adherence and coverage impact in endemic and prone-epidemic prevention and control in sub-Sahara Africa. Methods: The scoping review method was applied in acknowledged journals indexing platforms including Medline, Embase, Global Health, PubMed, MeSH PsycInfo, Scopus and Google Scholar to identify relevant articles pertaining to telemonitoring as a proxy surrogate method in reinforcing sustainability of HIV/TB prevention/treatment interventions in sub-Saharan Africa...
2017: Health Promotion Perspectives
https://www.readbyqxmd.com/read/28321877/pharmacological-interventions-for-acute-hepatitis-b-infection-an-attempted-network-meta-analysis
#7
REVIEW
Konstantinos Mantzoukis, Manuel Rodríguez-Perálvarez, Elena Buzzetti, Douglas Thorburn, Brian R Davidson, Emmanuel Tsochatzis, Kurinchi Selvan Gurusamy
BACKGROUND: Infection with hepatitis B virus (HBV) can be symptomatic or asymptomatic. Apart from chronic HBV infection, the complications related to acute HBV infection are severe acute viral hepatitis and fulminant hepatitis characterised by liver failure. The optimal pharmacological treatment of acute HBV infection remains controversial. OBJECTIVES: To assess the benefits and harms of pharmacological interventions in the treatment of acute HBV infection through a network meta-analysis and to generate rankings of the available treatments according to their safety and efficacy...
March 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28319753/the-impact-of-cannabis-and-cannabinoids-for-medical-conditions-on-health-related-quality-of-life-a-systematic-review-and-meta-analysis
#8
REVIEW
Matthew Goldenberg, Mark William Reid, Waguih William IsHak, Itai Danovitch
INTRODUCTION: The use of cannabis or cannabinoids to treat medical conditions and/or alleviate symptoms is increasingly common. However, the impact of this use on patient reported outcomes, such as health-related quality of life (HRQoL), remains unclear. METHODS: We conducted a systematic review and meta-analysis, employing guidelines from Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We categorized studies based on design, targeted disease condition, and type of cannabis or cannabinoid used...
March 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28303533/urban-health-in-tanzania-questioning-the-urban-advantage
#9
Francis Levira, Gemma Todd
How are health inequalities articulated across urban and rural spaces in Tanzania? This research paper explores the variations, differences, and inequalities, in Tanzania's health outcomes-to question both the idea of an urban advantage in health and the extent of urban-rural inequalities in health. The three research objectives aim to understand: what are the health differences (morbidity and mortality) between Tanzania's urban and rural areas; how are health inequalities articulated within Tanzania's urban and rural areas; and how are health inequalities articulated across age groups for rural-urban Tanzania? By analyzing four national datasets of Tanzania (National Census, Household Budget Survey, Demographic Health Survey, and Health Demographic Surveillance System), this paper reflects on the outcomes of key health indicators across these spaces...
March 16, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28294590/successful-omalizumab-treatment-in-hiv-positive-patient-with-chronic-spontaneous-urticaria-a-case-report
#10
E Iemoli, F Niero, L Borgonovo, M V Cossu, S Piconi
We described a case of a 56 year old homosexual HIV positive man who presented a history of CSU since one year (2012). All the allergologic, immunologic and microbiologic tests to evaluate the pathogenesis of wheals resulted negative. Therefore in June 2015 we decided to start therapy with Omalizumab while the patient kept on effective antiretroviral therapy with 310 cells/mm3 TCD4 counts and undetectable HIV viremia. After two monthly subcutaneuous injection of 150 mg of Omalizumab the patient had no more urticarial symptoms...
March 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28294498/respiratory-health-status-is-impaired-in-uk-hiv-positive-adults-with-virologically-suppressed-hiv-infection
#11
J Brown, J A McGowan, H Chouial, S Capocci, C Smith, D Ivens, M Johnson, L Sathia, R Shah, F C Lampe, A Rodger, M Lipman
OBJECTIVES: We sought to evaluate whether people living with HIV (PLWH) using effective antiretroviral therapy (ART) have worse respiratory health status than similar HIV-negative individuals. METHODS: We recruited 197 HIV-positive and 93 HIV-negative adults from HIV and sexual health clinics. They completed a questionnaire regarding risk factors for respiratory illness. Respiratory health status was assessed using the St George's Respiratory Questionnaire (SGRQ) and the Medical Research Council (MRC) breathlessness scale...
March 13, 2017: HIV Medicine
https://www.readbyqxmd.com/read/28291302/psychosocial-group-interventions-to-improve-psychological-well-being-in-adults-living-with-hiv
#12
REVIEW
Ingrid van der Heijden, Naeemah Abrahams, David Sinclair
BACKGROUND: Being diagnosed with human immunodeficiency virus (HIV), and labelled with a chronic, life-threatening, and often stigmatizing disease, can impact on a person's well-being. Psychosocial group interventions aim to improve life-functioning and coping as individuals adjust to the diagnosis. OBJECTIVES: To examine the effectiveness of psychosocial group interventions for improving the psychological well-being of adults living with HIV/AIDS. SEARCH METHODS: We searched the following electronic databases up to 14 March 2016: the Cochrane Central Register of Controlled Trials (CENTRAL) published in the Cochrane Library (Issue 2, 2016), PubMed (MEDLINE) (1996 to 14 March 2016), Embase (1996 to 14 March 2016), and Clinical Trials...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28282245/live-with-the-disease-like-you-used-to-before-you-knew-you-were-infected-a-qualitative-study-among-10-year-survivors-living-with-hiv-in-haiti
#13
Samuel Pierre, Vanessa Riviera, Circee Phara Jean, Marie Jude Jean Louis, Lindsey K Reif, Patrice Severe, Vanessa Rouzier, Warren D Johnson, Jean W Pape, Daniel W Fitzgerald, Margaret L McNairy, Carla Boutin-Foster
In 2003, the Haitian Study Group on Kaposi's Sarcoma and Opportunistic Infections (GHESKIO), a nonprofit organization, began administering antiretroviral therapy (ART) to its patients. This practice transformed HIV from a fatal disease to a more manageable chronic condition. However, relatively few studies focus on the experiences of survivors. This study provided a unique opportunity to interview patients who survived at least 10 years after being treated with ART at GHESKIO. The goal of the study was to elicit from patients their perspectives on what enabled them to survive with AIDS...
March 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28278753/psychological-distress-among-ugandan-adolescents-living-with-hiv-examining-stressors-and-the-buffering-role-of-general-and-religious-coping-strategies
#14
Massy Mutumba, Jose A Bauermeister, Gary W Harper, Victor Musiime, James Lepkowski, Ken Resnicow, Rachel C Snow
HIV infection increases the risk of psychological distress among adolescents living with HIV (ALHIV), which, in turn, increases risky behaviours such as medication non-adherence, substance use, and sexual risk-taking. The majority of studies on psychological distress among ALHIV have been conducted in high-income countries; data on the prevalence and correlates of psychological distress among ALHIV in sub-Saharan Africa (SSA) are scarce, yet over two-thirds of the global population of ALHIV resides in SSA. The purpose of this study was to identify the contextually relevant correlates of psychological distress among Ugandan ALHIV...
April 11, 2016: Global Public Health
https://www.readbyqxmd.com/read/28278567/screening-for-depression-among-youth-with-hiv-in-an-integrated-care-setting
#15
Audra St John Walsh, Katherine L Wesley, Sim Yin Tan, Courtney Lynn, Kimberly O'Leary, Yan Wang, Diep Nguyen, Tiffany Chenneville, Carina A Rodriguez
Youth living with HIV (YLWH) are at risk for depression. Depressive symptoms can impact treatment engagement, health outcomes, and quality of life. Early identification of symptoms can guide treatment planning. This study aimed to identify trends in depressive symptoms for YLWH in a specialty-care clinic and follow-up clinical treatment procedures. An archival review of a clinical database provided depression screening information for a sample of 130 YLWH between 11 and 25 years old in the southeastern United States...
February 13, 2017: AIDS Care
https://www.readbyqxmd.com/read/28278562/depression-partially-mediated-the-relationship-between-basic-psychological-needs-and-quality-of-life-among-people-living-with-hiv
#16
Zahraa Majeed, Edwin van Wijngaarden, James G Dolan, Krupa N Shah
Few studies have examined the relationship between basic psychological needs (BPN), depression and quality of life (QOL) in people living with HIV (PLWH). This cross-sectional study (N = 65; 37% females, 37% Caucasian, mean age = 55 ± 6 years, mean CD4 count = 668 ± 368 cells/mm(3), average duration of HIV = 18 ± 4 years) found that BPN frustration was related with lower QOL. The strength of this relationship was reduced after controlling for depression. This suggests that depression partially mediated the relationship between BPN and QOL...
March 5, 2017: AIDS Care
https://www.readbyqxmd.com/read/28275444/the-impact-of-thailand-s-public-health-response-to-the-hiv-epidemic-1984-2015-understanding-the-ingredients-of-success
#17
EDITORIAL
Taweesap Siraprapasiri, Sumet Ongwangdee, Patchara Benjarattanaporn, Wiwat Peerapatanapokin, Mukta Sharma
INTRODUCTION: Thailand has been heralded as a global leader in HIV prevention and treatment, and its experience with the HIV/AIDS epidemic holds valuable lessons for public health. This paper documents Thailand's response to its HIV epidemic from the late 1980s until today, and analyses its epidemiological impact (incidence and mortality). We discuss the association between the trajectory of HIV incidence and mortality rates over time, and the programmatic investments, policies and interventions that were implemented in the last three decades...
November 28, 2016: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28266230/the-introduction-of-syphilis-point-of-care-tests-in-resource-limited-settings
#18
Michael Marks, David Cw Mabey
Syphilis remains an important and preventable cause of stillbirth and neonatal mortality. About 1 million women with active syphilis become pregnant each year. Without treatment, 25% of them will deliver a stillborn baby and 33% a low birth weight baby with an increased chance of dying in the first month of life. Adverse pregnancy outcomes due to syphilis can be prevented by screening pregnant women, and treating those who test positive with a single dose of penicillin before 28 weeks' gestation. Areas covered: This manuscript covers the impact of syphilis on pregnancy outcome, the diagnosis of syphilis, with a special focus on point of care (POC) tests, and challenges to the introduction of POC tests, and their potential impact on the control and prevention of syphilis in resource limited settings...
March 14, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/28264630/female-sex-workers-empowerment-strategies-amid-hiv-related-socioeconomic-vulnerabilities-in-cameroon
#19
Charles W Cange, Matthew LeBreton, Karen Saylors, Serge Billong, Ubald Tamoufe, Pamella Fokam, Stefan Baral
Research has consistently demonstrated that female sex workers use a variety of empowerment strategies to protect one another and their families. This study examines the strategies Cameroonian sex workers employ to do so. In-depth interviews and focus-group discussions were conducted with 100 sex workers. Coded texts were analysed for recurring themes. Sex workers reported being concerned with physical violence and sexual assault and demands from authorities for bribes to avoid fines and/or imprisonment. Women described strategies such as 'looking out for' each other when faced with security threats...
March 7, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28264016/how-are-women-living-with-hiv-in-france-coping-with-their-perceived-side-effects-of-antiretroviral-therapy-results-from-the-eve-study
#20
Guillemette Quatremère, Marguerite Guiguet, Patricia Girardi, Marie-Noëlle Liaud, Coline Mey, Cynthia Benkhoucha, Franck Barbier, Graciela Cattaneo, Anne Simon, Daniela Rojas Castro
OBJECTIVE: Side effects of antiretroviral therapy (ART) can have a negative impact on health-related quality of life threatening long-term retention in HIV care and adherence to ART. The aim of the French community-based survey EVE was to document personal experiences with side effects, the related physician-patient communication, and solutions found to deal with them. DESIGN: Cross-sectional study of women between September 2013 to September 2014. METHODS: An anonymous online questionnaire included the HIV Symptom Distress Module, which explores 20 symptoms...
2017: PloS One
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