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HIV and Quality of Life

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https://www.readbyqxmd.com/read/29789984/the-role-of-hiv-stigma-in-art-adherence-and-quality-of-life-among-rural-women-living-with-hiv-in-india
#1
Maria L Ekstrand, Elsa Heylen, Amanda Mazur, Wayne T Steward, Catherine Carpenter, Kartik Yadav, Sanjeev Sinha, Adey Nyamathi
HIV stigma continues to be a barrier to physical and mental health among people living with HIV globally, especially in vulnerable populations. We examined how stigma is associated with health outcomes and quality of life among rural women living with HIV in South India (N = 600). Interviewer-administered measures assessed multiple dimensions of stigma, as well as loneliness, social support, ART adherence, time since diagnosis, and quality of life. Internalized stigma and a lack of social support were associated with a lower quality of life, while the association between internalized stigma and adherence was mediated by the use of stigma-avoidant coping strategies, suggesting that keeping one's diagnosis a secret may make it more difficult to take one's medications...
May 22, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29783965/unmet-basic-needs-negatively-affect-health-related-quality-of-life-in-people-aging-with-hiv-results-from-the-positive-spaces-healthy-places-study
#2
Phan Sok, Sandra Gardner, Tsegaye Bekele, Jason Globerman, Mary V Seeman, Saara Greene, Michael Sobota, Jay J Koornstra, LaVerne Monette, Keith Hambly, Stephen W Hwang, James Watson, Glen Walker, Sean B Rourke
BACKGROUND: Basic needs (e.g., food security and stable housing) are important determinants of health and well-being, yet their impact on health-related quality of life (HRQoL) in the context of HIV and aging has not been systematically investigated. METHODS: Multiple linear regression models examined the relationship between unmet basic needs, and physical and mental HRQoL by age strata (20-34, 35-49 and 50+) in a cross-sectional sample of 496 people living with HIV in Ontario, Canada...
May 21, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29771096/-patient-physician-relation-a-grounded-theory-of-the-experience-of-hiv-treatment-side-effects
#3
Caroline Dufour, Marilou Gagnon
Antivirals induce many significant side effects and reduce the quality of life for People Living with HIV (PLWHIV). The management of side effects is crucial to maintain the patient's quality of life and adherence to treatments. The patient-physician relation is essential when managing side effects as it influences the experience for the PLWHIV. This grounded theory analyzes the patient-physician relationship in context with side effects. In the greater Ottawa/Gatineau area, 50 PLWHIV have participated in a semi-structured interview to share their experience with side effects...
March 2018: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/29769038/impact-of-new-daa-therapy-on-real-clinical-practice-a-multicenter-region-wide-cohort-study
#4
Simone Lanini, Paola Scognamiglio, Alessandra Mecozzi, Lorella Lombardozzi, Vincenzo Vullo, Mario Angelico, Antonio Gasbarrini, Gloria Taliani, Adolfo Francesco Attili, Carlo Federico Perno, Adriano De Santis, Vincenzo Puro, Fabio Cerqua, Gianpiero D'Offizi, Adriano Pellicelli, Orlando Armignacco, Francesco Saverio Mennini, Massimo Siciliano, Enrico Girardi, Vincenzo Panella, Giuseppe Ippolito
BACKGROUND: Management of chronic hepatitis C (CHC) has significantly accelerated in the last few years. Currently, second generation direct acting antivirals (DAAs) promise clearance of infection in most of patients. Here we present the results of the first analysis carried out on data of Lazio clinical network for DAAs. METHODS: The study was designed as a multicenter cohort: a) to assess the evolution of treatment during the first 24 months of the activity of the Clinical Network; b) to report overall efficacy of treatments; c) to analyze potential factors associated with lack of virological response at 12 weeks after therapy (SVR12); d) to evaluate the variation of ALT at baseline and 12 weeks after therapy in those who achieved SVR12 in comparison to those who did not...
May 16, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29764440/psychometric-properties-of-the-korean-version-of-the-medical-outcomes-study-hiv-health-survey-results-from-a-multicenter-survey-in-korea
#5
Eun-Jung Shim, Hyeju Ha, Sun Hee Lee, Nam Joong Kim, Eu Suk Kim, Ji Hwan Bang, Kyoung-Ho Song, Bo Kyung Sohn, Hye Youn Park, Kyung-Lak Son, Heesung Hwang, Kwang-Min Lee, Bong-Jin Hahm
BACKGROUND: Precise assessment of health-related quality of life (HRQOL) with a reliable and valid measure is a prerequisite to the enhancement of HRQOL. This study examined the psychometric properties of the Korean version of the Medical Outcomes Study HIV Health Survey (K-MOS-HIV). METHODS: The reliability and validity of the K-MOS-HIV were examined in a multicenter survey involving 201 outpatients with human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS) from four teaching hospitals throughout Korea...
May 15, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29750006/a-novel-integrated-cognitive-behavioral-therapy-for-anxiety-and-medication-adherence-among-persons-living-with-hiv-aids
#6
Charles P Brandt, Daniel J Paulus, Monica Garza, Chad Lemaire, Peter J Norton, Michael J Zvolensky
Persons living with HIV/AIDS (PLHIV) are able to live full lifespans after infection, however, rates of anxiety disorders among this population are elevated compared to national samples. Importantly, these anxiety symptoms and disorders have a negative effect on medication adherence, quality of life and other psychological disorders, such as depression. In order to reduce the impact of anxiety among PLHIV, a six-session transdiagnostic CBT-based treatment manual for anxiety among PLHIV named the HIV/Anxiety Management-Reduction Treatment (HAMRT) was developed and implemented...
February 2018: Cognitive and Behavioral Practice
https://www.readbyqxmd.com/read/29748343/physical-activity-among-hiv-positive-patients-receiving-antiretroviral-therapy-in-hanoi-and-nam-dinh-vietnam-a-cross-sectional-study
#7
Anh Kim Dang, Long Hoang Nguyen, Anh Quynh Nguyen, Bach Xuan Tran, Tung Thanh Tran, Carl A Latkin, Melvyn W B Zhang, Roger C M Ho
OBJECTIVES: Antiretroviral therapy (ART) has facilitated the transition of HIV infection into a chronic disease, where adherence to medications is required along with keeping a healthy lifestyle. Therefore, an increase in physical activity has been recommended for patients with HIV in order to maintain their health status. This study looked to determine the physical activity level and its associated factors among patients with HIV receiving ART treatment. SETTINGS: Eight outpatient clinic sites across different levels of the health systems in both rural and urban settings in Hanoi and Nam Dinh, Vietnam...
May 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29746617/a-wake-up-call-for-human-immunodeficiency-virus-hiv-providers-obstructive-sleep-apnea-in-people-living-with-hiv
#8
Robert L Owens, Charles B Hicks
Obstructive sleep apnea (OSA) is defined by repetitive collapse of the upper airway during sleep leading to transient hypoxemia and arousals from sleep. Surges in sympathetic activity, repeated oxygen desaturation, and sleep fragmentation can lead to cardiovascular (eg, myocardial infarction) and neurocognitive (eg, excessive daytime sleepiness) consequences. Emerging data suggest that OSA is common in people living with human immunodeficiency virus (PLWH) and that traditional risk factors for OSA, such as obesity, are not highly predictive of OSA in PLWH...
May 9, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29740676/adverse-reactions-associated-with-first-line-regimens-in-patient-initiating-antiretroviral-therapy
#9
Jullye Campos Mendes, Palmira de Fátima Bonolo, Maria das Graças Braga Ceccato, Juliana de Oliveira Costa, Adriano Max Moreira Reis, Henrique Dos Santos, Micheline Rosa Silveira
OBJECTIVE: To evaluate the prevalence of adverse drug reactions (ADR) and associated factors during the use of Highly Active Antiretroviral Therapy (HAART) in patients initiating treatment. METHODS: This is a cross-sectional analysis of a prospective study conducted in three public referral services specialized in HIV/AIDS care in Belo Horizonte, Brazil. Self-reported ADR and explanatory variables were obtained from face-to-face interview and from Information Systems...
May 8, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29736274/burden-of-physical-psychological-and-social-ill-health-during-and-after-pregnancy-among-women-in-india-pakistan-kenya-and-malawi
#10
Mary McCauley, Barbara Madaj, Sarah A White, Fiona Dickinson, Sarah Bar-Zev, Mamuda Aminu, Pamela Godia, Pratima Mittal, Shamsa Zafar, Nynke van den Broek
Introduction: For every woman who dies during pregnancy and childbirth, many more suffer ill-health, the burden of which is highest in low-resource settings. We sought to assess the extent and types of maternal morbidity. Methods: Descriptive observational cross-sectional study at primary-level and secondary-level healthcare facilities in India, Pakistan, Kenya and Malawi to assess physical, psychological and social morbidity during and after pregnancy. Sociodemographic factors, education, socioeconomic status (SES), quality of life, satisfaction with health, reported symptoms, clinical examination and laboratory investigations were assessed...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/29736073/a-study-of-neuropsychological-profile-of-human-immunodeficiency-virus-positive-children-and-adolescents-on-antiretroviral-therapy
#11
Vasantmeghna S Murthy, Ajita S Nayak, Minal K Joshi, Kaneenica Ninawe
Aims: The aim is to study the neuropsychological and functional profile of children and adolescents with human immunodeficiency virus (HIV) infection on antiretroviral therapy (ART) and the association between the neuropsychological status and medical illness variables, treatment variables, and functional status in the cases of the sample and compare with normal controls. Materials and Methods: Forty-two HIV-positive children and adolescents on ART were evaluated and compared with 40 matched controls not known to be HIV-positive...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29733939/ethnic-differences-and-comorbidities-of-909-prurigo-nodularis-patients
#12
Emily Boozalis, Olive Tang, Shivani Patel, Yevgeniy R Semenov, Manuel P Pereira, Sonja Stander, Sewon Kang, Shawn G Kwatra
BACKGROUND: Prurigo Nodularis (PN) is a poorly understood, understudied pruritic dermatosis that reduces quality of life. OBJECTIVE: To characterize the demographics and comorbidities associated with PN. METHODS: Cross-sectional study of patients ≥ 18 years old seen at the Johns Hopkins Health System (JHHS) between 12/6/2012-12/6/2017. RESULTS: Over the last five years, 909 patients with PN were seen at JHHS. African-American patients were 3...
May 4, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29732363/human-milk-oligosaccharides-and-associations-with-immune-mediated-disease-and-infection-in-childhood-a-systematic-review
#13
Alice M Doherty, Caroline J Lodge, Shyamali C Dharmage, Xin Dai, Lars Bode, Adrian J Lowe
Complex sugars found in breastmilk, human milk oligosaccharides (HMOs), may assist in early-life immune programming and prevention against infectious diseases. This study aimed to systematically review the associations between maternal levels of HMOs and development of immune-mediated or infectious diseases in the offspring. PubMed and EMBASE databases were searched (last search on 22 February 2018) according to a predetermined search strategy. Original studies published in English examining the effect of HMOs on immune-mediated and infectious disease were eligible for inclusion...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29731602/universal-rapid-human-immunodeficiency-virus-screening-at-delivery-a-cost-effectiveness-analysis
#14
Rachel K Scott, Stacia Crochet, Chun-Chih Huang
Objective: To determine the cost-effectiveness of universal maternal HIV screening at time of delivery to decrease mother-to-child transmission (MTCT), by comparing the cost and quality-adjusted life years (QALYs) of universal rapid HIV screening at time of delivery to two current standards of care for prenatal HIV screening in the United States. Study Design: We conducted a cost-effectiveness analysis to compare the cost and QALY of universal intrapartum rapid HIV screening with two current standards of care: (I) opt-out rapid HIV testing limited to patients without previous third-trimester screening and (II) opt-out rapid HIV testing limited to patients without any prenatal screening...
2018: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29724705/recommendations-for-the-development-of-a-mobile-hiv-prevention-intervention-for-men-who-have-sex-with-men-and-hijras-in-mumbai-qualitative-study
#15
Shruta Rawat, J Michael Wilkerson, Sylvia M Lawler, Pallav Patankar, B R Simon Rosser, Kanjani Shukla, Seyram Butame, Maria L Ekstrand
BACKGROUND: As Internet and mobile phone use expands in India, there is an opportunity to develop mobile health (mHealth) interventions for marginalized populations, including men who have sex with men (MSM) and hijras (transgender women), hesitant to access traditional health care systems. OBJECTIVE: The purpose of this study was to determine if an mHealth intervention was acceptable to MSM and hijras living in Mumbai, and if so, what features would be useful in targeting the prevention of HIV acquisition and to increase the quality of life among persons living with HIV/AIDS...
May 3, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29718965/comparison-of-pain-burden-and-psychological-factors-in-brazilian-women-living-with-hiv-and-chronic-neuropathic-or-nociceptive-pain-an-exploratory-study
#16
Andressa de Souza, Wolnei Caumo, Prisla Ucker Calvetti, Rachel Nunes Lorenzoni, Gisele Keller da Rosa, Alexandre Ramos Lazzarotto, Jairo Alberto Dussan-Sarria
Psychological factors including pain catastrophizing and resilience associate with adjustment and quality of life in people living with chronic pain. Nevertheless, their presentation among females living with HIV and chronic pain has been poorly studied. Given that chronic pain in those living with HIV might occur due to different mechanisms (nociceptive or neuropathic), we hypothesize that the associated psychological states could also differ between these groups. We aimed to compare pain frequency and interference, psychological factors and sleep quality between females living with chronic nociceptive or neuropathic pain...
2018: PloS One
https://www.readbyqxmd.com/read/29718082/integration-of-neuropsychological-services-in-a-va-hiv-primary-care-clinic
#17
Moira C Dux, Terry Lee-Wilk
The Department of Veteran Affairs (VA) is the largest health care provider for individuals with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), with >28,000 Veterans with HIV/AIDS enrolled in care. Advances in medical treatment have improved the life-limiting effects of the disease, though many chronic symptoms persist. Comprehensive care is critical to manage the diverse constellation of symptoms. However, many patients face challenges to receiving optimal care due to limited resources, mistrust of health care providers, and/or co-occurring medical, psychiatric, and substance use disorders...
May 1, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29717630/knowledge-and-causal-attributions-for-mental-disorders-in-hiv-positive-children-and-adolescents-results-from-rural-and-urban-uganda
#18
W Nalukenge, F Martin, J Seeley, E Kinyanda
Increasing availability of antiretroviral treatment (ART) has led HIV to be considered a chronic disease, shifting attention to focus on quality of life including mental wellbeing. We investigated knowledge and causal attributions for mental disorders in HIV-positive children and adolescents in rural and urban Uganda. This qualitative study was nested in an epidemiological mental health study among HIV-positive children and adolescents aged 5-17 years in rural and urban Uganda. In-depth interviews were conducted with caregivers of HIV-positive children (5-11 years) and adolescents (12-17 years) in HIV care...
May 2, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29705605/the-role-of-catecholamines-in-hiv-neuropathogenesis
#19
R Nolan, P J Gaskill
The success of anti-retroviral therapy has improved the quality of life and lifespan of HIV+ individuals, transforming HIV infection into a chronic condition. These improvements have come with a cost, as chronic HIV infection and long-term therapy have resulted in the emergence of a number of new pathologies. This includes a variety of the neuropathological and neurocognitive effects collectively known as HIVassociated neurocognitive disorders (HAND) or NeuroHIV. These effects persist even in the absence of viral replication, suggesting that they are mediated the long-term changes in the CNS induced by HIV infection rather than by active replication...
April 26, 2018: Brain Research
https://www.readbyqxmd.com/read/29692315/impact-of-infectious-diseases-on-population-health-using-incidence-based-disability-adjusted-life-years-dalys-results-from-the-burden-of-communicable-diseases-in-europe-study-european-union-and-european-economic-area-countries-2009-to-2013
#20
Alessandro Cassini, Edoardo Colzani, Alessandro Pini, Marie-Josee J Mangen, Dietrich Plass, Scott A McDonald, Guido Maringhini, Alies van Lier, Juanita A Haagsma, Arie H Havelaar, Piotr Kramarz, Mirjam E Kretzschmar, On Behalf Of The BCoDE Consortium
Background and aimsThe Burden of Communicable Diseases in Europe (BCoDE) study aimed to calculate disability-adjusted life years (DALYs) for 31 selected diseases in the European Union (EU) and European Economic Area (EEA). Methods: DALYs were estimated using an incidence-based and pathogen-based approach. Incidence was estimated through assessment of data availability and quality, and a correction was applied for under-estimation. Calculation of DALYs was performed with the BCoDE software toolkit without applying time discounting and age-weighting...
April 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
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