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HIV and Quality of Life

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https://www.readbyqxmd.com/read/27906007/what-happens-to-cardiovascular-system-behind-the-undetectable-level-of-hiv-viremia
#1
REVIEW
Gabriella d'Ettorre, Giancarlo Ceccarelli, Paolo Pavone, Pietro Vittozzi, Gabriella De Girolamo, Ivan Schietroma, Sara Serafino, Noemi Giustini, Vincenzo Vullo
Despite the combined antiretroviral therapy has improved the length and quality of life of HIV infected patients, the survival of these patients is always decreased compared with the general population. This is the consequence of non-infectious illnesses including cardio vascular diseases. In fact large studies have indicated an increased risk of coronary atherosclerotic disease, myocardial infarction even in HIV patients on cART. In HIV infected patients several factors may contribute to the pathogenesis of cardiovascular problems: life-style, metabolic parameters, genetic predisposition, viral factors, immune activation, chronic inflammation and side effects of antiretroviral therapy...
April 27, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27905351/-visualizing-research-lines-in-public-health-an-analysis-based-on-bibliometric-maps-applied-to-the-revista-espa%C3%A3-ola-de-salud-p%C3%A3%C2%BAblica-2006-2015
#2
Carmen Gálvez
OBJECTIVE: Identifying research lines is essential to understand the knowledge structure of a scientific domain. The aim of this study was to identify the main research topics of within the domain of public health, in the Revista Española de Saslud Pública during 2006-2015. METHODS: Original articles included in the Social Sciences Citation Index (SSCI) database, available online through the Web of Science (WoS), were selected. The analysis units used were the keywords, KeyWords Plus (KW+), extracted automatically by SSCI...
December 1, 2016: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/27904976/hiv-related-shame-and-health-related-quality-of-life-among-older-hiv-positive-adults
#3
Wilson Vincent, Xindi Fang, Sarah K Calabrese, Timothy G Heckman, Kathleen J Sikkema, Nathan B Hansen
This study investigated how HIV-related shame is associated with health-related quality of life (HRQoL) in older people living with HIV (PLHIV). Structural equation modeling tested whether HIV-related shame was associated with three dimensions of HRQoL (physical, emotional, and social well-being) and whether there were significant indirect associations of HIV-related shame with the three HRQoL dimensions via depression and loneliness in a sample of 299 PLHIV ≥50 years old. Results showed that depression and loneliness were key mechanisms, with depression at least partially accounting for the association between HIV-related shame and both emotional and physical well-being, respectively, and loneliness accounting for the association between HIV-related shame and social well-being...
November 30, 2016: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27903303/associated-factors-of-self-reported-psychopathology-and-health-related-quality-of-life-among-men-who-have-sex-with-men-msm-with-hiv-aids-in-dalian-china-a-pilot-study
#4
Tesfaldet Habtemariam Hidru, Feng Wang, Sainyugu Lolokote, Yong Jia, Min Chen, Wei Tong, Xiao-Feng Li
BACKGROUND: Despite the availability of Anti-Retroviral Therapy (ART), the health-related quality of life (HRQoL) among HIV-positive men who have sex with men (HIVMSM) in China remains poor. This study aimed to explore the relationship between self-reported psychopathology and HRQoL among HIVMSM in Dalian, China. METHODS: A cross-sectional study was conducted in 112 HIVMSM. Symptom check list 90 (SCL 90): a measure of psychopathology and World Health Organization quality of life in HIV infection (WHOQOL-HIV-Bref): a measure of HRQoL were used...
December 1, 2016: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/27900931/hiv-positive-migrants-encounters-with-the-swedish-health-care-system
#5
Manijeh Mehdiyar, Rune Andersson, Katarina Hjelm, Lene Povlsen
BACKGROUND: There is limited knowledge about human immunodeficiency virus (HIV)-positive migrants and their experiences in the Swedish health care system. It is necessary to increase our knowledge in this field to improve the quality of care and social support for this vulnerable group of patients. OBJECTIVE: The aim of this study was to describe the experiences of HIV-positive migrants and their encounters with the health care system in Sweden. DESIGN: This is a Grounded Theory study based on qualitative interviews with 14 HIV-positive migrants living in Sweden, aged 29-55 years...
2016: Global Health Action
https://www.readbyqxmd.com/read/27893864/cost-effectiveness-of-the-one4all-hiv-linkage-intervention-in-guangxi-zhuang-autonomous-region-china
#6
Xiao Zang, Houlin Tang, Jeong Eun Min, Diane Gu, Julio S G Montaner, Zunyou Wu, Bohdan Nosyk
BACKGROUND: In Guangxi Zhuang Autonomous Region, China, an estimated 80% of newly-identified antiretroviral therapy (ART)-eligible patients are not engaged in ART. Delayed ART uptake ultimately translates into high rates of HIV morbidity, mortality, and transmission. To enhance HIV testing receipt and subsequent treatment uptake in Guangxi, the Chinese Center for Disease Control and Prevention (CDC) executed a cluster-randomized trial to assess the effectiveness and cost-effectiveness of a streamlined HIV testing algorithm (the One4All intervention) in 12 county-level hospitals...
2016: PloS One
https://www.readbyqxmd.com/read/27890944/role-of-high-sensitivity-c-reactive-protein-measurements-in-hiv-patients
#7
REVIEW
Arun Vishwanath, Saif Quaiser, Ruhi Khan
As we herald into the 21(st) century, the quality of life and the repertoire of highly active antiretroviral therapy (HAART) have considerably improved. However, considerable work is still needed to educate the population about primary and secondary prevention modalities. Moreover, regular monitoring of immune response with patients on HAART with conventional biomarkers is still a problem in low resource settings which needs to be addressed. We aim to review high-sensitivity C-reactive protein as a potential biomarker in this regard...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27890943/recapitulation-of-acquired-immuno-deficiency-syndrome-associated-kaposi-s-sarcoma
#8
REVIEW
Balaji Govindan
Acquired immuno deficiency syndrome (AIDS) associated Kaposi's sarcoma (KS) is one of the clinical forms of KS. KS is caused by human herpes viruses 8 or KS associated herpes virus (KSHV). In India, till now, only 16 cases of AIDS associated KS was reported. Of all the clinical forms of KS, AIDS associated KS is distinct in many ways viz.; cutaneous manifestations commonly affects face and trunk rather than lower limbs, more mucosal lesions, rapidly progressive, and early systemic involvement. When human immunodeficiency virus (HIV) is co-infected with KSHV, in addition to the other pathogenic factors for the development of KS, HIV Tat protein promotes the proliferation of cytokine-activated endothelial cells and stimulates KS...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27887666/contributions-of-national-and-global-health-estimates-to-monitoring-health-related-sustainable-development-goals
#9
Kanitta Bundhamcharoen, Supon Limwattananon, Khanitta Kusreesakul, Viroj Tangcharoensathien
The millennium development goals triggered an increased demand for data on child and maternal mortalities for monitoring progress. With the advent of the sustainable development goals and growing evidence of an epidemiological transition toward non-communicable diseases, policymakers need data on mortality and disease trends and distribution to inform effective policies and support monitoring progress. Where there are limited capacities to produce national health estimates (NHEs), global health estimates (GHEs) can fill gaps for global monitoring and comparisons...
2016: Global Health Action
https://www.readbyqxmd.com/read/27885046/the-role-of-basic-psychological-need-satisfaction-sleep-and-mindfulness-in-the-health-related-quality-of-life-of-people-living-with-hiv
#10
Rachel Campbell, Maarten Vansteenkiste, Liesbeth Delesie, Bart Soenens, Els Tobback, Dirk Vogelaers, An Mariman
Research has not yet examined the relationship between psychological need satisfaction, sleep, mindfulness, and health-related quality of life in people living with HIV. This cross-sectional study (N = 101; 84% male; mean age = 45.48, SD = 12.75) found need satisfaction to relate positively to physical and mental health. Sleep quality fully mediated the association with physical health and partially mediated the association with mental health. Furthermore, mindfulness related to higher sleep quality through higher need satisfaction...
November 23, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27878297/hydroxyproline-containing-collagen-peptide-derived-from-the-skin-of-the-alaska-pollack-inhibits-hiv-1-infection
#11
In Seung Jang, Sun Joo Park
The human immunodeficiency virus (HIV) is a lentivirus that results in acquired immunodeficiency syndrome (AIDS). HIV treatment involving chemical therapeutic agents has improved the quality of life of HIV/AIDS patients. The present study demonstrates that a hydroxyproline-containing marine collagen peptide (APHCP) derived from Alaska pollack inhibits HIV‑1 infection in the MT-4 human T cell‑line. APHCP inhibited HIV-1IIIB-induced cell lysis, syncytia formation, reverse transcriptase activity and viral p24 production at non‑cytotoxic concentrations; however, APHCP did not inhibit HIV‑2ROD infection in MT‑4 cells...
November 16, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27875835/the-relevance-of-palliative-care-in-hiv-and-aging
#12
Jacqueline Shorthill, Rosanna F DeMarco
The connection between palliative care and HIV infection has deep and wide roots in the United States that go back to the time when many gay men in the early 1980s were dying from a disease we knew little about, and there was no way to help but to alleviate symptoms in hospice and end of life centers across the United States. More individuals (adults and children), families, and communities attribute the success of antiretroviral therapies and other therapeutic approaches to advancing quality of life and life itself today...
2017: Interdisciplinary Topics in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27875827/disability-among-persons-aging-with-hiv-aids
#13
Suzanne G Leveille, Saurja Thapa
Persons surviving to older ages with HIV/AIDS often face an accelerated aging accompanied by increased comorbidity and decline in health and function. In this chapter, we review the process of disablement among persons aging with HIV/AIDS, from chronic conditions to impairments and functional limitations, leading to disability. Chronic immune activation related to chronic HIV infection may contribute to early development of chronic conditions that are common in older adults resulting in premature disablement...
2017: Interdisciplinary Topics in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27875824/multimorbidity-and-burden-of-disease
#14
Todd T Brown, Giovanni Guaraldi
With effective antiretroviral therapy, HIV has become a chronic disease, and life expectancy among HIV-infected persons is approaching that of HIV-uninfected persons. Despite this success, epidemiologic evidence suggests that the burden of multiple aging-related diseases, including cardiovascular disease, liver disease, metabolic abnormalities, chronic kidney disease, cognitive dysfunction, and osteoporosis, is higher in HIV-infected persons compared to their HIV-uninfected peers. These comorbid diseases tend to cluster in a single person, leading to multimorbidity and polypharmacy...
2017: Interdisciplinary Topics in Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27872004/hiv-and-men
#15
REVIEW
Haci Ibrahim Cimen, Arie Stewart Parnham, Ege Can Serefoglu
INTRODUCTION: Since the initial description of HIV and AIDS, monumental efforts have been made both in the developed and developing countries to devise strategies and medications to control the disease. The advent of highly active antiretroviral therapy has now meant that the diagnosis of HIV is no longer a life-sentence and compliant patients with HIV can expect life expectancy similar to their noninfected peers. Consequently new challenges have arisen in the management of benign conditions...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27864625/the-impact-of-comorbidities-depression-and-substance-use-problems-on-quality-of-life-among-older-adults-living-with-hiv
#16
Brett M Millar, Tyrel J Starks, Sitaji Gurung, Jeffrey T Parsons
Older adults living with HIV (OALWH) comprise a growing population with a range of complex and interconnecting medical and psychosocial needs. Based on the biopsychosocial model with its emphasis on a holistic approach to various aspects of people's lives, the current study explored associations between physical health, psychological health, substance use, and overall quality of life. Drawing on data from 114 substance-using OALWH (aged 50 or older), we employed linear regression to show associations between the number of current comorbid health conditions on quality of life, over and above depression, substance use problems, and demographic characteristics (age, race/ethnicity, gender, sexual orientation, education, and relationship status)...
November 18, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27863194/pomalidomide-for-symptomatic-kaposi-s-sarcoma-in-people-with-and-without-hiv-infection-a-phase-i-ii-study
#17
Mark N Polizzotto, Thomas S Uldrick, Kathleen M Wyvill, Karen Aleman, Cody J Peer, Margaret Bevans, Irini Sereti, Frank Maldarelli, Denise Whitby, Vickie Marshall, Priscila H Goncalves, Vikram Khetani, William D Figg, Seth M Steinberg, Jerome B Zeldis, Robert Yarchoan
Purpose Kaposi's sarcoma (KS) is a multicentric tumor caused by Kaposi's sarcoma-associated herpesvirus. Unmet needs include therapies that are oral, anthracycline sparing, and deliverable in resource-limited settings. We evaluated pomalidomide, an oral immune modulatory agent, in patients with symptomatic KS. Methods The primary objectives were to assess tolerability, pharmacokinetics, and activity. Initial dosage level was 5 mg once per day for 21 days per 28-day cycle, with a de-escalated level of 3 mg if not tolerable, and aspirin 81 mg once per day thromboprophylaxis...
December 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27852291/shifting-human-resources-for-health-in-the-context-of-art-provision-qualitative-and-quantitative-findings-from-the-lablite-baseline-study
#18
Misheck J Nkhata, Margaret Muzambi, Deborah Ford, Adrienne K Chan, George Abongomera, Harriet Namata, Ivan Mambule, Annabelle South, Paul Revill, Caroline Grundy, Travor Mabugu, Levison Chiwaula, James Hakim, Cissy Kityo, Andrew Reid, Elly Katabira, Sumeet Sodhi, Charles F Gilks, Diana M Gibb, Janet Seeley, Fabian Cataldo
BACKGROUND: Lablite is an implementation project supporting and studying decentralized antiretroviral therapy (ART) rollout to rural communities in Malawi, Uganda and Zimbabwe. Task shifting is one of the strategies to deal with shortage of health care workers (HCWs) in ART provision. Evaluating Human Resources for Health (HRH) optimization is essential for ensuring access to ART. The Lablite project started with a baseline survey whose aim was to describe and compare national and intercountry delivery of ART services including training, use of laboratories and clinical care...
November 16, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27849111/pharmacological-interventions-for-pruritus-in-adult-palliative-care-patients
#19
REVIEW
Waldemar Siemens, Carola Xander, Joerg J Meerpohl, Sabine Buroh, Gerd Antes, Guido Schwarzer, Gerhild Becker
BACKGROUND: This is an update of the original Cochrane review published in 2013 (Issue 6). Pruritus occurs in patients with disparate underlying diseases and is caused by different pathologic mechanisms. In palliative care patients, pruritus is not the most prevalent but is one of the most puzzling symptoms. It can cause considerable discomfort and affects patients' quality of life. OBJECTIVES: To assess the effects of different pharmacological treatments for preventing or treating pruritus in adult palliative care patients...
November 16, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27842557/exercise-stereotypes-and-health-related-outcomes-in-french-people-living-with-hiv-development-and-validation-of-an-hiv-exercise-stereotypes-scale-hivess
#20
Laura Gray, Charlène Falzon, Alessandro Bergamaschi, Laura Schuft, Jacques Durant, Eric Rosenthal, Christian Pradier, Martin Duracinsky, Isabelle Rouanet, Serge S Colson, Fabienne d'Arripe-Longueville
BACKGROUND: The main objective of the current study was to develop and validate a French exercise stereotype scale for people living with HIV (PLHIV) in order to gain visibility to the possible barriers and facilitators for exercise in PLHIV and thus enhance their quality of life. METHODS: A series of four complementary studies was carried out with a total sample of 524 participants to: (a) develop a preliminary version of the HIV Exercise Stereotype Scale (HIVESS) (Stage 1), (b) confirm the factorial structure of the instrument (Stage 2), (c) evaluate the stability of the instrument (Stage 3), and (d) examine the construct and divergent validity of the scale (Stage 4)...
November 14, 2016: Health and Quality of Life Outcomes
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