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https://www.readbyqxmd.com/read/29752555/minimally-invasive-surgery-procedure-in-isthmic-spondylolisthesis
#1
Francesco Ciro Tamburrelli, Maria Concetta Meluzio, Aaron Burrofato, Andrea Perna, Luca Proietti
PURPOSE: The aim of the study was to evaluate the efficacy and safety of the direct lateral approach to the lumbar spine in the treatment of painful isthmic spondylolisthesis in adults. METHODS: Twenty-one patients affected by isthmic spondylolisthesis and treated with extreme lateral interbody fusion and posterior percutaneous pedicle screw fixation were enrolled. All included patients were clinically evaluated with Oswestry Disability Index, SF36 and Visual Scale Anatomy (VAS) for back pain at 1, 3 months and at 1 year...
May 11, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29746993/combination-of-exercise-and-acupuncture-vs-acupuncture-alone-for-treatment-of-myofascial-pain-syndrome-a-randomized-clinical-trial
#2
Bina Eftekharsadat, Elmira Porjafar, Fariba Eslamian, Seyed Kazem Shakouri, Hamid Reza Fadavi, Seyed Ahmad Raeissadat, Arash Babaei-Ghazani
Myofascial pain syndrome (MPS) is a common musculoskeletal disorder. This study was designed to compare the effects of aerobic exercise plus acupuncture with acupuncture alone in treatment of patients with MPS. Sixty four patients (55 female and 9 male) with myofascial pain syndrome in their neck and shoulders participated in the study with mean age of 33.1± 6.4. Participants were randomly allocated to aerobic exercise plus acupuncture (n = 32) or acupuncture alone (n = 32) groups. Outcome measurements included Visual Analog Scale (VAS), Pressure Pain Threshold (PPT), Neck Disability Index (NDI) and Quality of Life which was measured with QoL-SF36 scale...
May 7, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29726939/the-effects-of-ustekinumab-on-health-related-quality-of-life-in-patients-with-moderate-to-severe-crohn-s-disease
#3
Bruce E Sands, Chenglong Han, Christopher Gasink, Douglas Jacobstein, Philippe Szapary, Long-Long Gao, Yinghua Lang, Stephan Targan, William J Sandborn, Brian G Feagan
Background and Aims: We assessed the effect of ustekinumab on health-related quality of life (HRQOL) in adults with Crohn's disease (CD). Methods: Patients with moderately-to-severely active CD and inadequate response or intolerance to tumor necrosis factor antagonists (UNITI1, N=741), or conventional therapy (UNITI-2, N=627) were randomized to placebo, ustekinumab 130 mg, or 6 mg/kg intravenous induction therapy. At Week 8, ustekinumab-treated responders (CDAI reduction≥100 or CDAI<150 points) were re-randomized to subcutaneous maintenance therapy (IM-UNITI, N=388) with placebo, ustekinumab 90mg q12w, or q8w for 44 additional weeks...
May 3, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29722640/extracorporeal-shockwave-therapy-for-intermittent-claudication-medium-term-outcomes-from-a-double-blind-randomised-placebo-controlled-pilot-trial
#4
Jordan Luke Green, Amy Elizabeth Harwood, George Edward Smith, Tushar Das, Ali Raza, Thomas Cayton, Tom Wallace, Daniel Carradice, Ian Clifford Chetter
Objectives Peripheral arterial disease most commonly presents as intermittent claudication (IC). Early evidence has suggested that extracorporeal shockwave therapy is efficacious in the short term for the management of intermittent claudication. The objective of this pilot trial was to evaluate the medium-term efficacy of this treatment. Methods This double-blind randomised placebo-controlled pilot trial randomised patients with unilateral intermittent claudication in a 1:1 fashion to receive extracorporeal shockwave therapy or a sham treatment for three sessions per week over three weeks...
January 1, 2018: Vascular
https://www.readbyqxmd.com/read/29705914/a-longitudinal-study-of-painless-and-painful-intercostobrachial-neuropathy-after-breast-cancer-surgery
#5
S La Cesa, P Sammartino, C Mollica, G Cascialli, G Cruccu, A Truini, M Framarino-Dei-Malatesta
Intercostobrachial neuropathy, often resulting in neuropathic pain, is a common complication of breast cancer surgery. In this 1-year longitudinal study, we aimed at seeking information on the frequency, clinical features, and course of painless and painful intercostobrachial neuropathy. We enrolled 40 women previously undergoing breast cancer surgery. In these patients, we collected, at 3, 6 and 12 months after surgery, clinical and quantitative sensory testing (QST) variables to diagnose intercostobrachial neuropathy, DN4 questionnaire to identify neuropathic pain, Neuropathic Pain Symptom Inventory to assess the different neuropathic pain symptoms, the Beck Depression Inventory to assess depressive symptoms, and SF36 to assess quality of life and Patient Global Impression of Change...
April 29, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29698250/the-analgesic-and-emotional-response-to-intravenous-lidocaine-infusion-in-the-treatment-of-postherpetic-neuralgia-a-randomized-double-blinded-placebo-controlled-study
#6
Hui Liu, Fan Lu, Dan Zhou, Yan Yin, Jun Li, BangXiang Yang, Li Song, Ling Ye, Hong Xiao
OBJECTIVES: This study evaluates the analgesic efficacy and emotional response of intravenous lidocaine infusion compared with placebo in patients with postherpetic neuralgia(PHN). METHODS: In this randomized, double-blinded study, patients with PHN received 5▒mg/kg intravenous lidocaine infusion or placebo. The primary outcome was pain relief measured by Visual Analogue Scale (VAS), Von Frey and area of allodynia. Moreover, emotional status of anxiety and depression were evaluated by Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS)...
April 25, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29694512/quality-of-life-on-hemodialysis-and-inflammation-a-descriptive-analysis
#7
M R Bacci, F Adami, F W S Figueiredo, B C A Alves, G L da Veiga, F L A Fonseca
Chronic kidney disease (CKD) is highly prevalent worldwide. Patients with CKD on hemodialysis are more likely to present behavioral changes and worse quality of life as a result of their routine and complications. They also have higher levels of cytokines. The aim of this study is to assess the relationship between the inflammatory profile and quality of life measured by KDOQL-SF36 in hemodialysis outpatients. Patients older than 21 years of age and on routine hemodialysis for at least 6 months with treatment on a regular weekly basis were included and their anthropometric parameters and serum inflammatory markers were evaluated...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29687005/medium-long-term-radiographic-and-clinical-outcomes-after-surgical-treatment-of-intra-articular-tibial-pilon-fractures-by-three-different-techniques
#8
Carlo Biz, Andrea Angelini, Marco Zamperetti, Filippo Marzotto, Silvano Pierluigi Sperotto, Diego Carniel, Claudio Iacobellis, Pietro Ruggieri
Introduction: The goal of this retrospective, observational, case series study was to evaluate the medium-long-term clinical and radiographic results of the three most common surgical osteosynthesis techniques used for the treatment of articular tibial pilon fractures: ORIF, MIPO, and EF. Materials and Methods: A consecutive series of patients with articular pilon fractures who underwent surgery at our institution were enrolled in this study. Fractures were classified according to the Müller AO classification system...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29675674/osteoporotic-thoracolumbar-compression-fractures-long-term-retrospective-comparison-between-vertebroplasty-and-conservative-treatment
#9
Konstantinos Martikos, Tiziana Greggi, Cesare Faldini, Francesco Vommaro, Antonio Scarale
PURPOSE: To compare long term clinical and radiographic outcomes in osteoporotic vertebral compression fractures of the thoracolumbar spine treated with conservative treatment and percutaneous vertebroplasty. METHODS: The retrospective study with inclusion criteria focused on osteoporotic fractures of the thoracolumbar junction (T10-L2). Clinical outcomes were evaluated by using the VAS, Oswestry and SF36 questionnaires. Radiographic outcomes were evaluated by comparing the following sagittal parameters: body angle, sagittal index of fractured vertebral body and adjacent vertebral segments kyphosis...
April 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29660525/gastric-peroral-endoscopic-pyloromyotomy-reduces-symptoms-increases-quality-of-life-and-reduces-healthcare-usage-for-patients-with-gastroparesis
#10
Parit Mekaroonkamol, Sunil Dacha, Lei Wang, Xiaoyu Li, Yueping Jiang, Lianyong Li, Tian Li, Nikrad Shahnavaz, Sonali Sakaria, Francis E LeVert, Steven Keilin, Field Willingham, Jennifer Christie, Qiang Cai
BACKGROUND AND AIMS: Gastric per-oral endoscopic pyloromyotomy (GPOEM) is becoming a promising treatment option for patients with refractory gastroparesis. We aimed to systematically assess the efficacy of GPOEM and its effects on healthcare usage. METHODS: We performed a retrospective study on 30 patients with refractory gastroparesis who underwent GPOEM from June 2015 through July 2017 at a tertiary center. We compared outcomes with those of 7 patients with refractory gastroparesis who did not undergo the procedure (controls)...
April 13, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29649527/recommendations-for-evaluation-and-management-of-pain-in-patients-with-mucopolysaccharidosis-in-latin-america
#11
J M Politei, G Gordillo-González, N Guelbert, C F M Souza, C M Lourenço, M L Solano, M M Junqueira, T S P C Magalhães, A M Martins
The mucopolysaccharidosis (MPS) constitute a heterogeneous group of rare genetic disorders caused by enzymatic deficiencies that lead to the accumulation of glycosaminoglycans (GAGs). Several types of MPS are described, historically numbered from I to IX. Clinical observations strongly suggest the presence of chronic pain in patients with all types of MPS. There are few data in the literature on the evaluation and management of pain in these patients, a fact which can compromise the quality of life even more...
April 9, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29614328/recommendations-for-evaluation-and-management-of-pain-in-patients-with-mucopolysaccharidosis-in-latin-america
#12
J M Politei, G Gordillo-González, N Guelbert, C F M Souza, C M Lourenço, M L Solano, M M Junqueira, T S P C Magalhães, A M Martins
The mucopolysaccharidosis (MPS) constitute a heterogeneous group of rare genetic disorders caused by enzymatic deficiencies that lead to the accumulation of glycosaminoglycans (GAGs). Several types of MPS are described, historically numbered from I to IX. Clinical observations strongly suggest the presence of chronic pain in patients with all types of MPS. There are few data in the literature on the evaluation and management of pain in these patients, a fact which can compromise the quality of life even more...
March 31, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29609220/burden-of-psoriatic-arthritis-in-different-definitions-of-disease-activity-comparing-minimal-disease-activity-and-disease-activity-index-for-psoriatic-arthritis
#13
Kim Wervers, Marijn Vis, Ilja Tchetverikov, Andreas H Gerards, Marc R Kok, Cathelijne W Y Appels, Wiebo L van der Graaff, Johannes H L M van Groenendael, Lindy-Anne Korswagen, Josien J Veris-van Dieren, Johanna M W Hazes, Jolanda J Luime
OBJECTIVE: Treat-to-target strategies have improved outcomes in rheumatic diseases. In psoriatic arthritis (PsA), the proposed targets are the multidimensional target Minimal Disease Activity (MDA) and the articular target Disease Activity index for PsA (DAPSA). We aimed to compare burden of PsA in patients with low disease activity according to the two definitions MDA and DAPSA-Low Disease Activity (DAPSA-LDA), one year after diagnosis. METHODS: We obtained data on MDA, DAPSA-LDA and disease burden one year after diagnosis from patients included in the Dutch southwest early PsA cohort...
April 2, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29582172/gender-differences-in-the-presentation-of-dysphonia-related-to-laryngopharyngeal-reflux-disease-a-case-control-study
#14
Jérôme R Lechien, Kathy Huet, Mohamad Khalife, Anne-Françoise Fourneau, Camille Finck, Véronique Delvaux, Myriam Piccaluga, Bernard Harmegnies, Sven Saussez
OBJECTIVE: To investigate the voice quality impairments in patients with laryngopharyngeal reflux (LPR) according to the gender. DESIGN: Controlled multi-center study. MATERIALS AND METHODS: 80 LPR patients (40 males and 40 females) with reflux finding score (RFS) > 7 and reflux symptom index (RSI) > 13 were included and clinically compared according to gender. To be considered as LPR patients, subjects responded to an empiric therapeutic trial based on pantoprazole intake and diet recommendations for 3 months or had positive pH/Impedance metry...
March 26, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29571888/evaluation-of-the-quality-of-life-in-patients-followed-for-differentiated-cancer-of-the-thyroid
#15
Nassim Essabah Haraj, Hicham Bouri, Siham El Aziz, Samira Nani, Noureddine Habti, Asma Chadli
Thyroid cancer often has good prognosis but can impact quality of life. The objective of this study is to evaluate quality of life in patients treated for differentiated thyroid carcinoma and look for associated factors. An observational cross-sectional study with comparison group was conducted in the Endocrinology Department of the Ibn Rochd University Hospital between October 2013 and February 2015. The patient group included 124 adult patients followed for differentiated thyroid carcinoma; the control group comprised 124 healthy subjects of the same age...
March 20, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29567463/long-term-quality-of-life-of-caregivers-of-cardiac-arrest-survivors-and-the-impact-of-witnessing-a-cardiac-event-of-a-close-relative
#16
Janine Van't Wout Hofland, Veronique Moulaert, Caroline van Heugten, Jeanine Verbunt
BACKGROUND: The incidence of cardiac arrest is high, with a poor survival rate of 8-14%. Currently, only limited evidence is available about long-term consequences of cardiac arrest on quality of life of caregivers. AIMS: First, to determine the level of daily functioning and quality of life in caregivers of cardiac arrest survivors two years after the cardiac arrest. Second, to study the long-term impact of witnessing the event of a cardiac arrest. METHODS: A longitudinal cohort study including caregivers of cardiac arrest survivors...
March 19, 2018: Resuscitation
https://www.readbyqxmd.com/read/29529002/nrs20-combined-back-and-leg-pain-score-a-simple-and-effective-assessment-of-adult-spinal-deformity
#17
Derek T Cawley, Daniel Larrieu, Takashi Fujishiro, David Kieser, Louis Bossiere, Emre Acaroglu, Ahmet Alanay, Frank Kleinsteück, Ferran Pellisé, Francisco Sánchez Pérez-Grueso, Jean-Marc Vital, Olivier Gille, Ibrahim Obeid
STUDY DESIGN: Multicenter, prospective study of consecutive adult spinal deformity (ASD) patients. OBJECTIVE: To evaluate back and leg pain as a combined score in ASD and compare their relative and cumulative correlations with HRQOL and sagittal parameters. SUMMARY OF BACKGROUND DATA: Pain and disability are commonly reported in patients with ASD. This can affect their back, their legs or both. ASD-associated pain has been correlated with numerous health-related quality of life (HRQOL) scores and radiological parameters...
March 9, 2018: Spine
https://www.readbyqxmd.com/read/29495049/-restricted-sleep-as-a-secondary-psychosocial-consequence-of-facial-palsy
#18
Susanne Worrack, Orlando Guntinas-Lichius, Gerd Fabian Volk, Magdalena C Kaczmarek, Julia Mühleck, Katja Brenk-Franz, Bernhard M Strauß, Uwe Altmann
BACKGROUND: Facial palsy (FP) is a paralysis of facial muscles and one of the most common motor failures. It is associated with intense impairment of health related quality of life and depressive symptoms. Sleep disorders as a result of FP are often attributed to illness-related impairments, although psychosocial problems might also be the cause. This study examined the direct and indirect effects of FP on sleep quality. METHODS: The sample of this cross-sectional study included N = 81 patients with FP...
March 1, 2018: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/29490001/nitrogen-single-breath-washout-test-for-evaluating-exercise-tolerance-and-quality-of-life-in-patients-with-chronic-obstructive-pulmonary-disease
#19
C A L Deus, P S Vigário, F S Guimarães, A J Lopes
Pulmonary function tests (PFTs) traditionally used in clinical practice do not accurately predict exercise intolerance in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to assess whether the nitrogen single-breath washout (N2SBW) test explains exercise intolerance and poor quality of life in stable COPD patients. This cross-sectional study included 31 patients with COPD subjected to PFTs (including the N2SBW test) and a cardiopulmonary exercise test (CPET). Patients were also evaluated using the following questionnaires: the COPD assessment test (CAT), the 36-Item Short Form Health Survey (SF36) and St...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29459766/greater-corneal-nerve-loss-at-the-inferior-whorl-is-related-to-the-presence-of-diabetic-neuropathy-and-painful-diabetic-neuropathy
#20
Alise Kalteniece, Maryam Ferdousi, Ioannis Petropoulos, Shazli Azmi, Safwaan Adam, Hassan Fadavi, Andrew Marshall, Andrew J M Boulton, Nathan Efron, Catharina G Faber, Giuseppe Lauria, Handrean Soran, Rayaz A Malik
We assessed whether a measure of more distal corneal nerve fibre loss at the inferior whorl(IW) region is better than proximal measures of central corneal nerve damage in relation to the diagnosis of diabetic peripheral neuropathy(DPN), painful DPN and quality of life(QoL). Participants underwent detailed assessment of neuropathy, QoL using the SF36 questionnaire, pain visual analogue score(VAS), and corneal confocal microscopy(CCM). Corneal nerve fibre density (CNFD), branch density (CNBD) and length (CNFL) at the central cornea and inferior whorl length (IWL) and average(ANFL) and total(TNFL) nerve fibre length were compared in patients with and without DPN and between patients with and without painful DPN and in relation to QoL...
February 19, 2018: Scientific Reports
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