keyword
https://read.qxmd.com/read/38640860/sijunzi-decoction-a-classical-chinese-herbal-formula-improves-fatigue-symptoms-with-changes-in-gut-microbiota-in-chronic-fatigue-syndrome-a-randomized-double-blind-placebo-controlled-multi-center-clinical-trial
#1
JOURNAL ARTICLE
Liang Dai, Zhidong Liu, Wenjuan Zhou, Li Zhang, Minjie Miao, Lei Wang, Haibing Hua, Bing Wang, Guang Ji
BACKGROUD: Chronic fatigue syndrome (CFS) severely impact patients' quality of life and lacks well-acknowledged drug therapy. Sijunzi decoction (SJZD), a classical Chinese herbal formula, has been widely used for spleen deficiency syndrome like fatigue in China. However, there is a lack of evidence on the efficacy of SJZD in treating CFS. PURPOSE: To evaluate the efficacy and safety of SJZD for CFS. STUDY DESIGN: A multi-center, double-blinded, randomized controlled trial...
April 13, 2024: Phytomedicine
https://read.qxmd.com/read/38616570/robotic-assisted-and-exoskeleton-gait-training-effect-in-mental-health-and-fatigue-of-multiple-sclerosis-patients-a-systematic-review-and-a-meta-analysis
#2
REVIEW
Vasileios N Christodoulou, Dimitrios N Varvarousis, Georgios Ntritsos, Dimitrios Dimopoulos, Nikolaos Giannakeas, Georgios I Vasileiadis, Anastasios Korompilias, Avraam Ploumis
PURPOSE: Robotic and Exoskeleton Assisted Gait Training (REAGT) has become the mainstream gait training module. Studies are investigating the psychosocial effects of REAGT mostly as secondary outcomes. Our systematic review and meta-analysis aims to investigate the effects of REAGT in MS patients' mental health and fatigue. MATERIALS AND METHODS: We searched the electronic databases (Scopus, PubMed, Pedro, Cochrane Trials, Dare) for RCT studies fulfilling our inclusion criteria...
April 14, 2024: Disability and Rehabilitation
https://read.qxmd.com/read/38584653/comparison-of-high-intensity-laser-therapy-with-extracorporeal-shock-wave-therapy-in-the-treatment-of-patients-with-plantar-fasciitis-a-double-blind-randomized-clinical-trial
#3
RANDOMIZED CONTROLLED TRIAL
Marzieh Zare Bidoki, Mohammad Reza Vafaeei Nasab, Amidodin Khatibi Aghda
BACKGROUND: The most common cause of heel pain is plantar fasciitis (PF). Although conservative treatments relieve pain in more than 90% of patients, it may remain painful in some cases. This study aimed to compare High-intensity Laser Therapy (HILT) with Extracorporeal Shock Wave Therapy (ESWT) in patients with PF. METHODS: In this double-blinded randomized clinical trial (conducted in Yazd, Iran, from May 2020 to March 2021), patients were classified into two groups, including the ESWT and HILT, using online randomization...
March 2024: Iranian Journal of Medical Sciences
https://read.qxmd.com/read/38575104/the-mediating-role-of-pain-cognitions-and-pain-sensitivity-in-the-treatment-effect-of-perioperative-pain-neuroscience-education-in-people-undergoing-surgery-for-lumbar-radiculopathy
#4
JOURNAL ARTICLE
Wouter Van Bogaert, Eva Huysmans, Iris Coppieters, Jo Nijs, Koen Putman, Kelly Ickmans, Maarten Moens, Lisa Goudman, Lara Stas, Ronald Buyl
Though perioperative pain neuroscience education (PPNE) positively influences patients' surgical outcomes, little is known about the mechanisms behind this treatment's success. Therefore, this study aims to evaluate the potential mediating role of pain cognitions and pain sensitivity in the treatment effect of PPNE on postoperative quality of life in people undergoing surgery for lumbar radiculopathy. This secondary analysis uses data from 120 participants of a randomized controlled trial who were randomized to receive either PPNE or perioperative biomedical education before undergoing surgery for lumbar radiculopathy...
April 2, 2024: Journal of Pain
https://read.qxmd.com/read/38571727/a-comparison-of-two-obesity-related-hypoventilation-disorders-impact-on-sleep-quality-of-life-and-neurocognitive-outcomes-and-the-effects-of-positive-airway-pressure%C3%A2-therapy
#5
JOURNAL ARTICLE
Yizhong Zheng, Brendon J Yee, Keith Wong, Ronald R Grunstein, Amanda J Piper
STUDY OBJECTIVES: Symptom impact and neurocognitive function have not been previously compared between patients with obesity-associated hypoventilation disorders (obesity hypoventilation syndrome [OHS]) and hypoventilation in the setting of obesity and obstructive airways disease (OHAD). The aim of this study is to compare baseline sleep-related symptoms, health-related quality of life, and neurocognitive function between OHS and OHAD and the impact of PAP therapy on these outcomes. METHODS: Epworth Sleepiness Scale (ESS), Pittsburgh Sleepiness Quality Index (PSQI), SF36, and various neurocognitive tests, in addition to anthropometric, polysomnography, lung function, and blood gas data from participants with OHS and participants with OHAD, were included in the analysis...
2024: Sleep advances: a journal of the Sleep Research Society
https://read.qxmd.com/read/38519516/importance-of-modifiable-non-radiographic-functional-parameters-for-adult-spinal-deformity
#6
JOURNAL ARTICLE
Kozaburo Mizutani, Tetsuya Kobayashi, Issei Senoo, Mutsuya Shimizu, Hiroki Okayasu
We clarified non-radiographic physical parameters associated with the severity of adult spinal deformity (ASD) using community-dwelling adult volunteers. They were subjected to upright entire spine radiographs for standard radiographic parameters and the number of sagittal modifiers of SRS-Schwab ASD classification (Schwab-SM). Clinical evaluations included isometric muscle strength of trunk extensor (TEX), trunk flexor (TFL), quadriceps femoris (QF), gluteus maximus, and iliopsoas; range of motion (ROM) of hip, knee, ankle, and active back extension (BET); SF36 physical component score (PCS), VAS for back and knee pain, and the degree of ambulatory kyphosis (dTIA)...
March 22, 2024: Scientific Reports
https://read.qxmd.com/read/38491840/home-versus-hospital-rehabilitation-of-older-adults-following-hip-fracture-yields-similar-patient-reported-outcome-measures
#7
JOURNAL ARTICLE
Hanna S Schroeder, Avi Israeli, Meir Iri Liebergall, Omer Or, Wiessam Abu Ahmed, Ora Paltiel, Dan Justo, Eyal Zimlichman
The increase in hip fractures (HF) due to aging of the population and the rise in attractiveness of services provided at home following the COVID-19 pandemic, emphasize the need to compare outcomes of home versus hospital HF rehabilitation. To date, studies comparing the 2 services have focused primarily on clinical outcomes rather than patient-reported outcomes (PROs). This longitudinal observational study evaluated PROs of older adults with HF in the 2 settings. The SF36 questionnaire was used to measure PROs 3 times after surgery...
2024: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://read.qxmd.com/read/38485902/the-musculoskeletal-tumor-society-scoring-system-is-a-valid-subjective-and-objective-tool-to-evaluate-outcomes-of-surgical-treatment-of-patients-affected-by-upper-and-lower-extremity-tumors
#8
JOURNAL ARTICLE
A Rizzo, M Paderno, M F Saccomanno, F Milano, G Milano
PURPOSE: The main purpose of the present study was to evaluate if there is a difference between objective or subjective administration of the MSTS score in a cohort of patients affected by musculoskeletal oncological diseases. MATERIALS AND METHODS: All patients who underwent surgery for bone or soft tissue localization of neoplastic disease in lower or upper limb from June 2015 to June 2020 were considered eligible. In order to administer the score as a PROM, the MSTS was first translated and cross-culturally adapted in Italian...
March 14, 2024: Musculoskeletal Surgery
https://read.qxmd.com/read/38483435/longitudinal-impact-of-intracerebral-low-grade-glioma-disease-on-health-related-quality-of-life
#9
JOURNAL ARTICLE
Laurèl Rauschenbach, Pauline Bartsch, Alejandro N Santos, Anna Michel, Hanah H Gull, Pikria Ketelauri, Marvin Darkwah Oppong, Börge Schmidt, Celia Dobersalske, Tobias Blau, Yahya Ahmadipour, Ramazan Jabbarli, Karsten H Wrede, Ulrich Sure, Philipp Dammann
BACKGROUND: The aim of this study was to assess health-related quality of life (HRQOL) before and after treatment for intracerebral low-grade glioma. METHODS: Patients with low-grade glioma who underwent surgical tumor removal between 2012 and 2018 were eligible for this study. All individuals and their closest relatives received thorough preoperative (<seven days before surgery) and posttreatment (12 months after surgery) neuropsychological testing investigating quality of life...
March 14, 2024: Journal of Neurosurgical Sciences
https://read.qxmd.com/read/38479110/clinical-and-imaging-outcomes-of-different-phenotypes-of-axial-spondyloarthritis-5-year-analysis-of-the-desir-cohort
#10
JOURNAL ARTICLE
Alexandre Sepriano, Sofia Ramiro, Désirée van der Heijde, Anna Moltó, Cécile Gaujoux-Viala, Maxime Dougados, Robert Landewé
OBJECTIVES: To compare the long-term outcomes of three phenotypes of axial SpA (axSpA). METHODS: Patients with a clinical diagnosis of axSpA from the DESIR cohort were grouped into three phenotypes at baseline: 'Pure axSpA' ('Axial'), 'axSpA with peripheral signs' ('IBP+Peripheral') and 'axSpA at risk' ('At risk') by latent class analysis. Clinical and imaging data were collected up to 5 years. Clinical outcomes, measured in each visit, included disability (BASFI) and quality of life (QoL; SF36)...
March 2, 2024: Seminars in Arthritis and Rheumatism
https://read.qxmd.com/read/38460544/a-patient-centered-assessment-of-the-2016-acr-eular-myositis-response-criteria-evaluating-the-meaningfulness-of-response
#11
JOURNAL ARTICLE
Didem Saygin, Anjana Chandrasekhara Pillai, Siamak Moghadam-Kia, Chester V Oddis, Dianxu Ren, Catherine Najem, Harman Dhatt, Rohit Aggarwal
OBJECTIVES: The ACR-EULAR Myositis Response Criteria (Total Improvement Score [TIS]) is a composite measure calculated using changes in myositis core set measures. It is unclear if achieving improvement per TIS reflects improvement in any symptoms of myositis patients. In this study, we examined the association between achieving TIS improvement and patient-centered outcome measures (PCOMs). METHODS: Adults with myositis were enrolled in a prospective study with baseline and 6-month visits...
March 9, 2024: Rheumatology
https://read.qxmd.com/read/38458961/early-ambulation-impacts-on-quality-of-life-outcomes-positively-after-lower-limb-burn-injury-a-group-trajectory-analysis
#12
JOURNAL ARTICLE
Chelsea K Evans, Dana A Hince, Claudia J Tatlow, Pip C Pienaar, Piers Truter, Fiona M Wood, Max Bulsara, Aaron Berghuber, Paul M Gittings, Dale W Edgar
INTRODUCTION: Despite the challenges of providing burn care throughout the 2.5MKm2 jurisdiction of Western Australia, early intervention after injury remains a key premise of the multidisciplinary model of care applied by the State Adult Burn Unit (SABU) team. In particular, contemporary guidelines support the facilitation of early ambulation after lower limb burn and skin grafting. Thus, this study aimed to evaluate the association between the timing of ambulation after burn and surgery on quality of life (QoL) outcomes...
February 28, 2024: Burns
https://read.qxmd.com/read/38429110/first-contact-physiotherapy-an-evaluation-of-clinical-effectiveness-and-costs
#13
JOURNAL ARTICLE
Nicola Walsh, Serena Halls, Rachel Thomas, Alice Berry, Cathy Liddiard, Margaret Elizabeth Cupples, Heather Gage, Dan Jackson, Fiona Cramp, Hannah Stott, Paula Kersten, Justin Jagosh, Dave Foster, Peter Williams
BACKGROUND: First Contact Physiotherapy Practitioners (FCPPs) are embedded within general practice, providing expert assessment, diagnosis and management plans for patients with musculoskeletal disorders (MSKDs), without the prior need for GP consultation. AIM: To determine the clinical effectiveness and costs of FCPP-led compared to GP-led models of care. DESIGN AND SETTING: Multiple site case study design. UK GP practices. METHOD: General Practice sites were recruited representing three models: 1...
March 1, 2024: British Journal of General Practice
https://read.qxmd.com/read/38406376/preferences-adherence-and-satisfaction-three-years-of-treatment-experiences-of-people-with-multiple-sclerosis
#14
JOURNAL ARTICLE
Olaf Hoffmann, Friedemann Paul, Rocco Haase, Raimar Kern, Tjalf Ziemssen
BACKGROUND: To reduce the risk of long-term disability in people with Multiple Sclerosis (pwMS), an increasing number of disease-modifying immune therapies (DMT) are available, involving diverse mechanisms of action, levels of efficacy, treatment risks, and tolerability aspects. Including patient preferences and expectations in shared decision-making may improve treatment satisfaction, adherence, and persistence. PURPOSE: To investigate long-term alignment of individual preferences and expectations of pwMS with their actual DMT and its effect on treatment satisfaction, health-related quality of life (HRQoL), adherence, and treatment discontinuation...
2024: Patient Preference and Adherence
https://read.qxmd.com/read/38389408/erectile-dysfunction-in-patient-with-obstructive-sleep-apnea-effects-of-continuous-positive-airway-pressure
#15
JOURNAL ARTICLE
Hyeyun Kim, Keun Tae Kim, Won Chul Shin, Kwang Ik Yang, Ji Yong Ha, Yong Won Cho
BACKGROUND: Obstructive sleep apnea (OSA) is linked to various health complications, including erectile dysfunction (ED), which is more prevalent in individuals with OSA. This study explored ED in Korean OSA patients and assessed the impact of continuous positive airway pressure (CPAP) therapy on ED. METHODS: A total of 87 male patients with OSA from four different sleep centers underwent physical measurements and completed sleep and mental health (MH) questionnaires, including the Korean version of the International index of erectile function (IIEF), before and three months after initiating CPAP therapy...
December 2024: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://read.qxmd.com/read/38374685/completely-portal-robotic-lobectomy-in-lung-cancer-is-subcostal-specimen-removal-necessary
#16
JOURNAL ARTICLE
Murat Akkuş, Yunus Seyrek
BACKGROUND: The best place for specimen extraction is a relevant question since either after robotic or video-thoracoscopic lobectomy, both intercostal and subcostal routes can be potential extraction routes. In this study, we studied completely portal robotic lobectomies (CPRL-4) for pulmonary neoplasms to investigate the efficacy and feasibility of subcostal specimen removal by comparing the two techniques. MATERIAL AND METHODS: Between January 2014 and July 2021, data from 90 patients who underwent robotic thoracic surgery with a Da Vinci Surgical System SI (Intuitive Surgical Inc...
February 19, 2024: Acta Chirurgica Belgica
https://read.qxmd.com/read/38372523/-not-available
#17
JOURNAL ARTICLE
Sihem Mensi, Abir Ezzine, Teheni Dardouri, Mohamed Ben Rejeb, Maha Ben Fredj, Kaouther Chatti
INTRODUCTION: Differentiated thyroid cancer (DTC), despite its good prognosis, affects the quality of life (QOL) of patients by its physical and psychological repercussions and by the toxicity of treatment. A study of the quality of life as well as the potentially associated factors is necessary in order to carry out targeted actions. AIM: This work was conducted to assess the quality of life of patients treated for thyroid cancer. METHODS: 89 patients treated surgically and by iratherapy for DTC responded from January 2018 to December 2019 to the SF36 questionnaire in its validated version in Tunisian dialect...
May 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38358513/long-term-functional-outcomes-in-polytrauma-a-fundamentally-new-approach-is-needed-in-prediction
#18
JOURNAL ARTICLE
Simone Meakes, Natalie Enninghorst, Natasha Weaver, Benjamin M Hardy, Zsolt J Balogh
PURPOSE: Modern trauma care has reduced mortality but poor long-term outcomes with low follow-up rates are common with limited recommendations for improvements. The aim of this study was to describe the impact of severe injury on the health-related quality of life, specifically characterise the non-responder population and to identify modifiable predictors of poorer outcomes. METHODS: Five-year (2012-2016) prospective cohort study was performed at a level 1 trauma centre...
February 15, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38334259/health-related-quality-of-life-and-cognitive-function-in-children-with-crigler-najjar-syndrome-type-1
#19
JOURNAL ARTICLE
Noha El-Anwar, Mortada El-Shabrawi, Ola Omar Shahin, Reem Abdel Kareem, Ahmed Mohamed Salama, Sherif Baroudy
BACKGROUND: The aim of the study was to assess the health-related quality of life (HRQOL) and cognitive function in patients with Crigler-Najjar syndrome (CNS) type I and its impact on their lives. METHODS: Twenty-one patients diagnosed with CNS type I aged 1 month to 18 years in the Paediatric Hepatology Unit of Cairo University Children's Hospital were enrolled in this cross-sectional observational study. The patients' health-related quality of life (HRQOL) was assessed using the World Health Organization Quality Of Life BREF questionnaire (WHOQOL-BREF) and the Short Form 36 Health Survey Questionnaire (SF-36)...
February 9, 2024: Paediatrics and International Child Health
https://read.qxmd.com/read/38294621/the-influence-of-lifestyle-and-biological-factors-on-semen-variability
#20
JOURNAL ARTICLE
Hannah E Lyons, Prabin Gyawali, Nicola Mathews, Patience Castleton, Shadrack M Mutuku, Nicole O McPherson
PURPOSE: Semen parameters are subjected to within-individual variability over time. The driving factors for this variability are likely multi-factorial, with healthier lifestyle associated with better semen quality. The extent in which variations in individual's lifestyle contributes to within-individual semen variability is unknown. METHODS: A total of 116 repeat semen samples from 29 men aged 19-37 over 6 months were collected. Basic semen analysis as per 5th WHO manual and extended semen parameters (sperm DNA fragmentation, redox potential and lipid peroxidation, sperm binding to hyaluronan and hyperactive motility) were assessed...
January 31, 2024: Journal of Assisted Reproduction and Genetics
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