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https://www.readbyqxmd.com/read/28079260/an-experimentally-validated-couch-and-mlc-tracking-simulator-used-to-investigate-hybrid-couch-mlc-tracking
#1
Jakob Toftegaard, Rune Hansen, Thomas Ravkilde, Kristijan Macek, Per Rugaard Poulsen
PURPOSE/OBJECTIVE: Couch and MLC tracking are two novel techniques to mitigate intrafractional tumor motion on a conventional linear accelerator, but both techniques still have residual dosimetric errors. Here, we first propose and experimentally validate a software tool to simulate couch and MLC tracking, and then use the simulator to study hybrid couch-MLC tracking for improved tracking performance. MATERIALS AND METHODS: The tracking simulator requires a treatment plan and a motion trajectory as input and simulates the delivered monitor units and motion of all accelerator parts as function of time...
January 12, 2017: Medical Physics
https://www.readbyqxmd.com/read/28076435/walking-ahead-the-headed-social-force-model
#2
Francesco Farina, Daniele Fontanelli, Andrea Garulli, Antonio Giannitrapani, Domenico Prattichizzo
Human motion models are finding an increasing number of novel applications in many different fields, such as building design, computer graphics and robot motion planning. The Social Force Model is one of the most popular alternatives to describe the motion of pedestrians. By resorting to a physical analogy, individuals are assimilated to point-wise particles subject to social forces which drive their dynamics. Such a model implicitly assumes that humans move isotropically. On the contrary, empirical evidence shows that people do have a preferred direction of motion, walking forward most of the time...
2017: PloS One
https://www.readbyqxmd.com/read/28062328/optimal-nutrition-and-hydration-through-the-surgical-treatment-trajectory
#3
REVIEW
Carol DeNysschen, Mary E Platek, Drew Hemler, Nell Aronoff, Michelle L Zafron
OBJECTIVES: To review oncology nurses role of informational continuity in regards to nutrition and hydration to ensure continuity of care from one care center to another. DATA SOURCES: Peer-reviewed literature, PubMed, CINAHL, EMBASE, and web-based resources. CONCLUSION: Optimal nutrition and hydration during cancer treatment and survivorship requires assessment and preplanning of needs. Oncology nurses play a vital role in preparing patients and caregivers for optimal nutrition during the surgical treatment trajectory...
January 4, 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28061535/perioperative-goal-setting-consultations-by-surgical-colleagues-a-new-model-for-supporting-patients-families-and-surgeons-in-shared-decision-making
#4
Ana Berlin, Anastasia Kunac, Anne C Mosenthal
Patients with postoperative complications are often subjected to prolonged life-sustaining treatment based on erroneous assumptions about their goals of care. Shared decision making (SDM) is an evidence-based approach that helps ensure patients' wishes and values are honored in their course of treatment. Perioperative palliative care can help create goal-concordant trajectories of care for high risk, seriously ill, or complicated patients, through sophisticated prognostication, higher-level communication, and recommendations based on the best available evidence and patients' stated goals and priorities...
November 29, 2016: Annals of Palliative Medicine
https://www.readbyqxmd.com/read/28052046/fast-approximate-delivery-of-fluence-maps-for-imrt-and-vmat
#5
Marleen Balvert, David L Craft
In this article we provide a method to generate the trade-off between delivery time and fluence map matching quality for dynamically delivered fluence maps. At the heart of our method lies a mathematical programming model that, for a given duration of delivery, optimizes leaf trajectories and dose rates such that the desired fluence map is reproduced as well as possible. We begin with the single fluence map case and then generalize the model and the solution technique to the delivery of sequential fluence maps...
January 4, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28050345/functional-mri-vs-navigated-tms-to-optimize-m1-seed-volume-delineation-for-dti-tractography-a-prospective-study-in-patients-with-brain-tumours-adjacent-to-the-corticospinal-tract
#6
Carolin Weiss Lucas, Irada Tursunova, Volker Neuschmelting, Charlotte Nettekoven, Ana-Maria Oros-Peusquens, Gabriele Stoffels, Andrea Maria Faymonville, Shah N Jon, Karl Josef Langen, Hannah Lockau, Roland Goldbrunner, Christian Grefkes
BACKGROUND: DTI-based tractography is an increasingly important tool for planning brain surgery in patients suffering from brain tumours. However, there is an ongoing debate which tracking approaches yield the most valid results. Especially the use of functional localizer data such as navigated transcranial magnetic stimulation (nTMS) or functional magnetic resonance imaging (fMRI) seem to improve fibre tracking data in conditions where anatomical landmarks are less informative due to tumour-induced distortions of the gyral anatomy...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28048763/su-g-brc-10-feasibility-of-a-web-based-monte-carlo-simulation-tool-for-dynamic-electron-arc-radiotherapy-dear
#7
A Rodrigues, D Sawkey, Q Wu
PURPOSE: DEAR is a radiation therapy technique utilizing synchronized motion of gantry and couch during delivery to optimize dose distribution homogeneity and penumbra for treatment of superficial disease. Dose calculation for DEAR is not yet supported by commercial TPSs. The purpose of this study is to demonstrate the feasibility of using a web-based Monte Carlo (MC) simulation tool (VirtuaLinac) to calculate dose distributions for a DEAR delivery. METHODS: MC simulations were run through VirtuaLinac, which is based on the GEANT4 platform...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048673/su-f-t-288-impact-of-trajectory-log-files-for-clarkson-based-independent-dose-verification-of-imrt-and-vmat
#8
R Takahashi, T Kamima, H Tachibana
PURPOSE: To investigate the effect of the trajectory files from linear accelerator for Clarkson-based independent dose verification in IMRT and VMAT plans. METHODS: A CT-based independent dose verification software (Simple MU Analysis: SMU, Triangle Products, Japan) with a Clarksonbased algorithm was modified to calculate dose using the trajectory log files. Eclipse with the three techniques of step and shoot (SS), sliding window (SW) and Rapid Arc (RA) was used as treatment planning system (TPS)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048583/su-f-t-503-trajectory-modulated-arc-therapy-of-intracranial-lesions-development-of-a-standardized-path-based-technique-for-fully-dynamic-couch-gantry-modulated-treatments
#9
S Khan, E Chin, K Otto, L Xing, D Hristov, B Fahimian
PURPOSE: The integration of couch motion during arc delivery is necessitated to enable irradiation trajectories such as coronal arcs, and to enhance the geometrical sampling for dynamic deliveries to the highest extent. To enable such capability, a platform of Trajectory Modulated Arc Therapy (TMAT) is developed in conjunction with standardized noncollisional dynamic path-set for irradiation of intracranial lesions. METHODS: A generalized path-set was constructed through the combination of sagittal arcs (45 degrees from the CAX), axial arcs, and coronal arcs produced through modulation of the dynamic rotation of couch...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048582/th-ab-brb-03-4n-radiotherapy
#10
K Sheng
: Current state-of-the art digital C-arm medical linear accelerators are capable of delivering radiation treatments with high level of automation, which affords coordinated motions of gantry, couch, and multileaf collimator (MLC) with dose rate modulations. The new machine capacity has shown the potential to bring substantially improved radiation dosimetry and/or delivery efficiency to many challenging diseases. Combining an integrated beam orientation optimization algorithm with automated machine navigation, markedly improved dose conformity has been achieved using 4ρ therapy...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048155/th-ef-brb-04-4%C3%AF-dynamic-conformal-arc-therapy-dynamic-conformal-arc-therapy-dcat-for-sbrt
#11
T Chiu, T Long, A Modiri, Z Tian, A Sawant, Y Yan, S Jiang, X Gu
PURPOSE: To develop an efficient and effective trajectory optimization methodology for 4π dynamic conformal arc treatment (4π DCAT) with synchronized gantry and couch motion; and to investigate potential clinical benefits for stereotactic body radiation therapy (SBRT) to breast, lung, liver and spine tumors. METHODS: The entire optimization framework for 4π DCAT inverse planning consists of two parts: 1) integer programming algorithm and 2) particle swarm optimization (PSO) algorithm...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048115/mo-fg-campus-tep1-05-rapid-and-efficient-3d-dosimetry-for-end-to-end-patient-specific-qa-of-rotational-sbrt-deliveries-using-a-high-resolution-epid
#12
Y M Yang, B Han, L Xing, L Wang
PURPOSE: EPID-based patient-specific quality assurance provides verification of the planning setup and delivery process that phantomless QA and log-file based virtual dosimetry methods cannot achieve. We present a method for EPID-based QA utilizing spatially-variant EPID response kernels that allows for direct calculation of the entrance fluence and 3D phantom dose. METHODS: An EPID dosimetry system was utilized for 3D dose reconstruction in a cylindrical phantom for the purposes of end-to-end QA...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048105/su-g-bra-17-tracking-multiple-targets-with-independent-motion-in-real-time-using-a-multi-leaf-collimator
#13
Y Ge, P Keall, P Poulsen
PURPOSE: Multiple targets with large intrafraction independent motion are often involved in advanced prostate, lung, abdominal, and head and neck cancer radiotherapy. Current standard of care treats these with the originally planned fields, jeopardizing the treatment outcomes. A real-time multi-leaf collimator (MLC) tracking method has been developed to address this problem for the first time. This study evaluates the geometric uncertainty of the multi-target tracking method. METHODS: Four treatment scenarios are simulated based on a prostate IMAT plan to treat a moving prostate target and static pelvic node target: 1) real-time multi-target MLC tracking; 2) real-time prostate-only MLC tracking; 3) correcting for prostate interfraction motion at setup only; and 4) no motion correction...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047988/su-f-t-302-implementation-of-the-radcalc-image-analysis-tool-for-imrt-qa
#14
A Soldner, C Fitzherbert, F Zhou, C Hand
PURPOSE: To assess RadCalc as a means for analyzing fluence maps of IMRT QA patient plans. Eclipse generated fluence maps were compared to RadCalc fluence maps generated from both Eclipse parameters and from dynalog trajectory files. METHODS: Six IMRT plans consisting of fifty individual fields were compared both field-by-field and as composite plans. These plans were exported from Eclipse to RadCalc. Each plan was then delivered in QA mode on a Varian Clinac iX, while recording and saving the dynalog trajectory files...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047855/th-ab-brb-00-research-opportunities-with-digital-linear-accelerators
#15
Ke Sheng
: Current state-of-the art digital C-arm medical linear accelerators are capable of delivering radiation treatments with high level of automation, which affords coordinated motions of gantry, couch, and multileaf collimator (MLC) with dose rate modulations. The new machine capacity has shown the potential to bring substantially improved radiation dosimetry and/or delivery efficiency to many challenging diseases. Combining an integrated beam orientation optimization algorithm with automated machine navigation, markedly improved dose conformity has been achieved using 4ρ therapy...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047736/su-f-p-42-to-navigate-or-not-to-navigate-hdr-bt-in-recurrent-spine-lesions
#16
L Voros, G Cohen, M Zaider, Y Yamada
PURPOSE: We compare the accuracy of HDR catheter placement for paraspinal lesions using O-arm CBCT imaging combined with StealthStation navigation and traditional fluoroscopically guided catheter placement. METHODS: CT and MRI scans were acquired pre-treatment to outline the lesions and design treatment plans (pre-plans) to meet dosimetric constrains. The pre-planned catheter trajectories were transferred into the StealthStation Navigation system prior to the surgery...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047705/th-ef-brb-02-feasibility-of-optimization-for-dynamic-trajectory-radiotherapy
#17
M K Fix, D Frei, W Volken, D Terribilini, D M Aebersold, P Manser
PURPOSE: Over the last years, volumetric modulated arc therapy (VMAT) has been widely introduced into clinical routine using a coplanar delivery technique. However, VMAT might be improved by including dynamic couch and collimator rotations, leading to dynamic trajectory radiotherapy (DTRT). In this work the feasibility and the potential benefit of DTRT was investigated. METHODS: A general framework for the optimization was developed using the Eclipse Scripting Research Application Programming Interface (ESRAPI)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047685/su-f-j-151-evaluation-of-a-magnetic-resonance-image-gated-radiotherapy-system-using-a-motion-phantom-and-radiochromic-film
#18
J Lamb, J Ginn, D O'Connell, D Thomas, N Agazaryan, M Cao, Y Yang, D Low
PURPOSE: Magnetic resonance image (MRI) guided radiotherapy enables gating directly on target position for soft-tissue targets in the lung and abdomen. We present a dosimetric evaluation of a commercially-available FDA-approved MRI-guided radiotherapy system's gating performance using a MRI-compatible respiratory motion phantom and radiochromic film. METHODS: The MRI-compatible phantom was capable of one-dimensional motion. The phantom consisted of a target rod containing high-contrast target inserts which moved inside a body structure containing background contrast material...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047673/su-d-207a-06-pediatric-abdominal-organ-motion-quantified-via-a-novel-4d-mri-method
#19
J Uh, M J Krasin, J T Lucas, C Tinkle, T E Merchant, C Hua
PURPOSE: To develop a 4D MRI method for assessing respiration-induced abdominal organ motion in children receiving radiation therapy. METHODS: A 4D MRI using internal image-based respiratory surrogate has been developed and implemented on a clinical scanner (1.5T Siemens Avanto). Ten patients (younger group: N=6, 2-5 years, anesthetized; older group: N=4, 11-15 years) with neuroblastoma, Wilm's tumor rhabdomyosarcoma, or desmoplastic small round cell tumor received free breathing 4D MRI scans for treatment planning...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047620/th-cd-207a-12-impacts-of-inter-and-intra-fractional-organ-motion-for-high-risk-prostate-cancer-stereotactic-body-radiation-therapy
#20
N Hassan Rezaeian, Y Chi, Y Zhou, Z Tian, S Jiang, R Hannan, X Jia
PURPOSE: We are conducting a clinical trial on stereotactic body radiation therapy (SBRT) for high-risk prostate cancer. Doses to three targets, prostate, intra-prostatic lesion, and pelvic lymph node (PLN) region, are escalated to three different levels via simultaneous integrated boost technique. Inter-/intra-fractional organ motions deteriorate planned dose distribution. This study aims at developing a dose reconstruction system to comprehensively understand the impacts of organ motion in our clinical trial...
June 2016: Medical Physics
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