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https://www.readbyqxmd.com/read/28937578/trajectories-of-pain-severity-in-juvenile-idiopathic-arthritis-results-from-the-research-in-arthritis-in-canadian-children-emphasizing-outcomes-cohort
#1
N J Shiff, S Tupper, K Oen, J Guzman, H Lim, C H Lee, R Bryce, A M Huber, G Boire, P Dancey, B Feldman, R Laxer, P Miettunen, H Schmeling, K Watanabe Duffy, D M Levy, S Turvey, R Bolaria, A Bruns, D A Cabral, S Campillo, G Chedeville, D Ehrmann Feldman, E Haddad, K Houghton, N Johnson, R Jurencak, B Lang, M Larche, K Morishita, S Ramsey, J Roth, R Schneider, R Scuccimarri, L Spiegel, E Stringer, S M Tse, R Yeung, C M Duffy, L B Tucker
We studied children enrolled within 90 days of juvenile idiopathic arthritis (JIA) diagnosis in the Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh-Out) prospective inception cohort to identify longitudinal trajectories of pain severity and features that may predict pain trajectory at diagnosis. A total of 1062 participants were followed a median of 24.3 months (IQR = 16.0, 37.1 months). Latent trajectory analysis of pain severity, measured in a 100mm visual analogue scale, identified 5 distinct trajectories: (A) mild-decreasing pain (56...
September 18, 2017: Pain
https://www.readbyqxmd.com/read/28935362/modeling-oil-spill-trajectory-in-bosphorus-for-contingency-planning
#2
Şafak Nur Ertürk Bozkurtoğlu
Bosphorus, is a strongly driven international maritime route between the Black Sea and the Sea of Marmara and is a high risk area for oil spill due to the heavy tanker traffic. In this study an oil spill trajectory model was developed for investigating the potential risks of accidental oil spills in Bosphorus. The proposed oil spill trajectory model combines the surface current velocity data obtained from a calibrated hydrodynamic model with the advection, spreading, and evaporation processes that are effective only on the sea surface and dominant for a couple of hours after the oil spill...
September 18, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28928603/functional-capacity-and-motor-performance-of-upper-limbs-in-individuals-with-cerebellar-disorders-a-pilot-study
#3
Vivian Farahte Giangiardi, Sandra Maria Sbeghen F de Freitas, Flávia P de Paiva Silva, Renata Morales Banjai, Sandra Regina Alouche
In simple daily activities carried out by the upper limbs, the cerebellum is responsible for the adaptations required for the accurate movement based on previous experiences and external references. This paper aims to characterize the performance of the upper limbs after a cerebellar disease. We evaluated the digital and handgrip strength, dexterity, and function of the upper limbs. The motor performance of the upper limbs was assessed through the use of a digitizing tablet by performing aiming movements with the upper limb most affected by cerebellar disease and the paired limb of the healthy group...
2017: Behavioural Neurology
https://www.readbyqxmd.com/read/28925098/identification-of-the-trajectory-of-functional-decline-for-advance-care-planning-in-a-nursing-home-population
#4
Suanne Lawrence, Andrew Robinson, Kathy Eagar
OBJECTIVE: To identify diagnostic groups and the form of the trajectory of functional decline that has the potential to enhance advance care planning (ACP) in a nursing home (NH) population. METHODS: Retrospective, longitudinal study with dependent variable (function) derived from the Resident Classification Scale (RCS), 1997-2008. Trajectory modelling used linear and curvilinear terms. RESULTS: The organ failure or other residents have a linear average functional decline...
September 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28921538/a-fast-inverse-treatment-planning-strategy-facilitating-optimized-catheter-selection-in-image-guided-high-dose-rate-interstitial-gynecologic-brachytherapy
#5
Christian V Guthier, Antonio L Damato, Juergen W Hesser, Akila N Viswanathan, Robert A Cormack
PURPOSE: Interstitial high-dose-rate (HDR) brachytherapy is an important therapeutic strategy for the treatment of locally advanced gynecologic (GYN) cancers. The outcome of this therapy is determined by the quality of dose distribution achieved. This paper focuses on a novel yet simple heuristic for catheter selection for GYN HDR brachytherapy and their comparison against state of the art optimization strategies. The proposed technique is intended to act as a decision-supporting tool to select a favorable needle configuration...
September 18, 2017: Medical Physics
https://www.readbyqxmd.com/read/28912923/lack-of-needs-assessment-in-cancer-survivorship-care-and-rehabilitation-in-hospitals-and-primary-care-settings
#6
Charlotte Handberg, Charlotte Maria Jensen, Thomas Maribo
BACKGROUND: Formalized and systematic assessment of survivorship care and rehabilitation needs is prerequisite for ensuring cancer patients sufficient help and support through their cancer trajectory. Patients are often uncertain as to how to express and address their survivorship care and rehabilitation needs, and little is known about specific, unmet needs and the plans necessary to meet them. There is a call for both ensuring survivorship care and rehabilitation for cancer patients in need and further for documenting the specific needs related to the cancer disease and its treatment...
October 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28910614/movement-coding-at-the-mesoscale-in-posterior-parietal-cortex
#7
Jonathan R Whitlock
Neural correlates of movement planning have been studied most commonly using signals isolated from single cells. However, in this issue of Neuron, Wilber et al. (2017) show that movement trajectories are encoded and replayed in the collective activity of thousands of cells at a time in the posterior parietal cortex.
September 13, 2017: Neuron
https://www.readbyqxmd.com/read/28899609/constructing-experience-event-models-from-perception-to-action
#8
REVIEW
Lauren L Richmond, Jeffrey M Zacks
Mental representations of everyday experience are rich, structured, and multimodal. In this article we consider the adaptive pressures that led to human construction of such representations, arguing that structured event representations enable cognitive systems to more effectively predict the trajectory of naturalistic everyday activity. We propose an account of how cortical systems and the hippocampus (HPC) interact to construct, maintain, and update event representations. This analysis throws light on recent research on story comprehension, event segmentation, episodic memory, and action planning...
September 9, 2017: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/28890028/a-novel-technique-for-placement-of-sacro-alar-iliac-s2ai-screws-by-k-wire-insertion-using-intraoperative-navigation
#9
Kevin Phan, Julian Li, Gloria Giang, Ian Teng, Steven Phan, Nicholas Chang, Ralph Mobbs
Sacral-iliac fixation techniques may be indicated in the management of various lumbosacral pathologies including spinal degeneration, infection, tumour resection, fracture, pseudarthrosis, correction of spinal deformities involving long fusion constructs to the sacrum and cases with poor sacral fixation. There are a number of options for lumbosacral fixation each with their own advantages and disadvantages. Though S2-alar-iliac (S2AI) have demonstrated promising advantages over alternatives, the complex anatomy of the spinopelvic region demands precise insertion of the screws to create a biomechanically robust construct safely...
September 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28886415/burden-of-higher-lead-exposure-in-african-americans-starts-in-utero-and-persists-into-childhood
#10
Andrea E Cassidy-Bushrow, Alexandra R Sitarik, Suzanne Havstad, Sung Kyun Park, Lawrence F Bielak, Christine Austin, Christine Cole Johnson, Manish Arora
BACKGROUND: Recent public health lead crises in urban areas emphasize the need to better understand exposure to environmental toxicants, particularly in higher risk groups. Although African-American children have the highest prevalence of elevated blood lead levels in the United States, little is known about when this trajectory of disproportionate burden of lead exposure first emerges. OBJECTIVES: Using tooth-matrix biomarkers that directly measure fetal and early childhood metal levels, the primary goal of this study was to determine if there were racial disparities in lead levels during fetal development and early childhood...
September 5, 2017: Environment International
https://www.readbyqxmd.com/read/28882812/health-information-technology-hit-adaptation-refocusing-on-the-journey-to-successful-hit-implementation
#11
Po-Yin Yen, Ann Scheck McAlearney, Cynthia J Sieck, Jennifer L Hefner, Timothy R Huerta
In past years, policies and regulations required hospitals to implement advanced capabilities of certified electronic health records (EHRs) in order to receive financial incentives. This has led to accelerated implementation of health information technologies (HIT) in health care settings. However, measures commonly used to evaluate the success of HIT implementation, such as HIT adoption, technology acceptance, and clinical quality, fail to account for complex sociotechnical variability across contexts and the different trajectories within organizations because of different implementation plans and timelines...
September 7, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/28882607/efficacy-and-safety-in-frameless-robot-assisted-stereo-electroencephalography-seeg-for-drug-resistant-epilepsy
#12
I Ollivier, C Behr, H Cebula, A Timofeev, M Benmekhbi, M P Valenti, A M Staack, J Scholly, P Kehrli, E Hirsch, F Proust
INTRODUCTION: Stereo-electroencephalography (SEEG) is an invasive procedure, used to identify the epileptogenic zone that can be surgically removed in order to treat drug-resistant epilepsy. Frameless robot-assisted positioning of depth electrodes permits a 3D approach with different obliquities and trajectories. The objective of the present study was to evaluate the morbidity and the accuracy related to this frameless procedure. PATIENTS AND METHODS: Sixty-six patients were managed wherein 901 electrodes were implanted during a 6-year-period...
September 4, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28881258/time-frequency-analysis-to-a-particular-type-of-scattering-problems-involving-metallic-polymer-tubing-structures
#13
Abdelkader Elhanaoui, Elhoucein Aassif, Gérard Maze, Dominique Décultot
In this paper, recent studies of backscattered acoustic signals in thinner steel-polymer tubing structures have been presented. Reassigned smoothed pseudo Wigner-Ville (rspWV) analysis has been adopted in order to diminish the cross-term effect, and achieve high resolution spectral. Vibration modes, which are associated to the resonances of circumferential waves, have been determined by using the modal isolation plan representation. At normalized frequencies below 140, an appreciable influence from the polymer coating thickness on the A0(+) and S0 modes has been noticed...
August 19, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28876427/geographical-distribution-of-medical-graduates-from-a-public-university
#14
Oscarina da Silva Ezequiel, Giancarlo Lucchetti, Alessandra Lamas Granero Lucchetti, Maria Helena Senger, Lucas Braga, Rafael Lacerda, Marlon Filippo, Fernando Colugnati, Danette McKinley, Eliana Amaral
Objective: To evaluate the geographic distribution and career trajectory of medical graduates and the factors associated with their choice of practice location. Method: A cross-sectional study involving graduates from December 2001 to December 2010 was conducted. A self-administered questionnaire collected demographics and geographic information (place of birth, place of residence at the time of medical school admission, place of residency training and practice location), and reason for choosing the current location...
June 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28874209/subclinical-levels-of-anxiety-but-not-depression-are-associated-with-planning-performance-in-a-large-population-based-sample
#15
J M Unterrainer, K Domschke, B Rahm, J Wiltink, A Schulz, N Pfeiffer, K J Lackner, T Münzel, P S Wild, M Beutel
BACKGROUND: Major depression and anxiety disorders are known to negatively influence cognitive performance. Moreover, there is evidence for greater cognitive decline in older adults with generalized anxiety disorder. Except for clinical studies, complex executive planning functions and subclinical levels of anxiety have not been examined in a population-based sample with a broad age range. METHODS: Planning performance was assessed using the Tower of London task in a population-based sample of 4240 participants aged 40-80 years from the Gutenberg Health Study (GHS) and related to self-reported anxiety and depression by means of multiple linear regression analysis...
September 6, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28873069/fred-a-gpu-accelerated-fast-monte-carlo-code-for-rapid-treatment-plan-recalculation-in-ion-beam-therapy
#16
A Schiavi, M Senzacqua, S Pioli, A Mairani, G Magro, S Molinelli, M Ciocca, G Battistoni, V Patera
Ion beam therapy is a rapidly growing technique for tumor radiation therapy. Ions allow for a high dose deposition in the tumor region, while sparing the surrounding healthy tissue. For this reason, the highest possible accuracy in the calculation of dose and its spatial distribution is required in treatment planning. On one hand, commonly used treatment planning software solutions adopt a simplified beam-body interaction model by remapping pre-calculated dose distributions into a 3D water-equivalent representation of the patient morphology...
September 5, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28869885/development-and-validation-of-a-prognostic-index-for-6-and-12-month-mortality-in-hospitalized-older-adults
#17
Eva Gallego González, Francisco Javier Ortiz Alonso, Maria Teresa Vidán Astiz, Selene Soria Felix, Verónica García Cárdenas, John Omonte Guzmán, Pedro Abizanda, Maria Isabel Valadés Malagón, Silvia Oreja Sevilla, José Antonio Serra Rexach
BACKGROUND/AIM: Estimation of mortality in elderly patients is difficult yet very important when planning care. Previous tools are complicated or do no take into account some major determinants of mortality (i.e., frailty). We designed a simple, accurate, and non-disease-specific tool to predict individual mortality risk after hospital discharge in older adults. METHODS: Patients admitted to the Acute Geriatric Unit were assessed at adission and at discharge and contacted 6 and 12 months later...
July 23, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28867267/testing-and-linkage-to-hiv-care-in-china-a-cluster-randomised-trial
#18
Zunyou Wu, Zhenzhu Tang, Yurong Mao, Paul Van Veldhuisen, Walter Ling, David Liu, Zhiyong Shen, Roger Detels, Guanghua Lan, Lynda Erinoff, Robert Lindblad, Diane Gu, Houlin Tang, Lian Hu, Qiuying Zhu, Li Lu, Neal Oden, Albert L Hasson, Yan Zhao, Jennifer M McGoogan, Xianmin Ge, Nanci Zhang, Keming Rou, Jinhui Zhu, Hui Wei, Cynthia X Shi, Xia Jin, Jian Li, Julio S G Montaner
BACKGROUND: Multistage, stepwise HIV testing and treatment procedures can result in lost opportunities to provide timely antiretroviral therapy (ART). Incomplete engagement of patients along the care cascade translates into high preventable mortality. We aimed to identify whether a structural intervention to streamline testing and linkage to HIV health care would improve testing completeness, ART initiation, and viral suppression and reduce mortality. METHODS: We did a cluster-randomised, controlled trial in 12 hospitals in Guangxi, China...
August 31, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28860676/the-historical-disturbance-regime-of-mountain-norway-spruce-forests-in-the-western-carpathians-and-its-influence-on-current-forest-structure-and-composition
#19
Pavel Janda, Volodymyr Trotsiuk, Martin Mikoláš, Radek Bače, Thomas A Nagel, Rupert Seidl, Meelis Seedre, Robert C Morrissey, Stanislav Kucbel, Peter Jaloviar, Marián Jasík, Juraj Vysoký, Pavel Šamonil, Vojtěch Čada, Hana Mrhalová, Jana Lábusová, Markéta H Nováková, Miloš Rydval, Lenka Matějů, Miroslav Svoboda
In order to gauge ongoing and future changes to disturbance regimes, it is necessary to establish a solid baseline of historic disturbance patterns against which to evaluate these changes. Further, understanding how forest structure and composition respond to variation in past disturbances may provide insight into future resilience to climate-driven alterations of disturbance regimes. We established 184 plots (mostly 1000 m(2)) in 14 primary mountain Norway spruce forests in the Western Carpathians. On each plot we surveyed live and dead trees and regeneration, and cored around 25 canopy trees...
March 15, 2017: Forest Ecology and Management
https://www.readbyqxmd.com/read/28843373/prospective-clinical-implementation-of-a-novel-magnetic-resonance-tracking-device-for-real-time-brachytherapy-catheter-positioning
#20
Jose de Arcos, Ehud J Schmidt, Wei Wang, Junichi Tokuda, Kamal Vij, Ravi T Seethamraju, Antonio L Damato, Charles L Dumoulin, Robert A Cormack, Akila N Viswanathan
PURPOSE: We designed and built dedicated active magnetic resonance (MR)-tracked (MRTR) stylets. We explored the role of MRTR in a prospective clinical trial. METHODS AND MATERIALS: Eleven gynecologic cancer patients underwent MRTR to rapidly optimize interstitial catheter placement. MRTR catheter tip location and orientation were computed and overlaid on images displayed on in-room monitors at rates of 6 to 16 frames per second. Three modes of actively tracked navigation were analyzed: coarse navigation to the approximate region around the tumor; fine-tuning, bringing the stylets to the desired location; and pullback, with MRTR stylets rapidly withdrawn from within the catheters, providing catheter trajectories for radiation treatment planning (RTP)...
June 7, 2017: International Journal of Radiation Oncology, Biology, Physics
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