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https://www.readbyqxmd.com/read/28789700/two-different-protein-expression-profiles-of-oral-squamous-cell-carcinoma-analyzed-by-immunoprecipitation-high-performance-liquid-chromatography
#1
Soung Min Kim, Dasul Jeong, Min Keun Kim, Sang Shin Lee, Suk Keun Lee
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most dangerous cancers in the body, producing serious complications with individual behaviors. Many different pathogenetic factors are involved in the carcinogenesis of OSCC. Cancer cells derived from oral keratinocytes can produce different carcinogenic signaling pathways through differences in protein expression, but their protein expression profiles cannot be easily explored with ordinary detection methods. METHODS: The present study compared the protein expression profiles between two different types of OSCCs, which were analyzed through immunoprecipitation high-performance liquid chromatography (IP-HPLC)...
August 8, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28765772/anti-inflammatory-effects-of-nelumbo-leaf-extracts-and-identification-of-their-metabolites
#2
Eunkyo Park, Gyoung Deuck Kim, Min-Sun Go, Dodan Kwon, In-Kyung Jung, Joong Hyuck Auh, Jung-Hyun Kim
BACKGROUND/OBJECTIVES: Nelumbo leaves have been used in traditional medicine to treat bleeding, gastritis, hemorrhoids, and halitosis. However, their mechanisms have not been elucidated. MATERIALS/METHODS: The present study prepared two Nelumbo leaf extracts (NLEs) using water or 50% ethanol. Inflammatory response was induced with LPS treatment, and expression of pro-inflammatory mediators (inducible nitric oxide synthase, cyclooxygenase-2, tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and nitric oxide (NO) and prostaglandin E2 (PGE2) productions were assessed...
August 2017: Nutrition Research and Practice
https://www.readbyqxmd.com/read/28743086/effect-of-cinnamon-cinnamomum-verum-bark-essential-oil-on-the-halitosis-associated-bacterium-solobacterium-moorei-and-in-vitro-cytotoxicity
#3
Geneviève LeBel, Bruno Haas, Andrée-Ann Adam, Marie-Pier Veilleux, Amel Ben Lagha, Daniel Grenier
OBJECTIVES: Halitosis, also known as bad breath or oral malodour, is a condition affecting a large proportion of the population. Solobacterium moorei is a Gram-positive anaerobic bacterium that has been specifically associated with halitosis. In this study, we investigated the effects of essential oils, more particularly cinnamon bark oil, on growth, biofilm formation, eradication and killing, as well as hydrogen sulfide (H2S) production by S. moorei. METHODS: A broth microdilution assay was used to determine the antibacterial activity of essential oils...
July 12, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28742057/effect-of-photodynamic-therapy-in-the-reduction-of-halitosis-in-patients-with-multiple-sclerosis-clinical-trial
#4
Marcela Leticia Leal Gonçalves, Sandra Kalil Bussadori, Yara Dadalti Fragoso, Vinícius Vieira Belarmino da Silva, Alessandro M Deana, Ana Carolina Ciarcia, Erika Horácio Pinto, Anna Carolina Ratto Tempestini Horliana, Cristiane Miranda França
Smell and odours play a vital role in social interaction. Halitosis is a social problem that affects one-third of the population causing a negative impact in the quality of life. There is little knowledge on the prevalence and management of halitosis in Multiple Sclerosis (MS) patients. The present study aimed to evaluate the presence of halitosis in patients with MS when compared to a control group and the treatment with antimicrobial photodynamic therapy (aPDT) against halitosis. This is a case-control clinical study where 60 patients were evaluated: 30 MS patients in treatment at the Specialties Clinic School of Medicine, and 30 healthy patients, matched in age and gender, for the control group...
July 25, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28727160/the-long-term-effect-of-a-zinc-acetate-and-chlorhexidine-diacetate-containing-mouth-rinse-on-intra-oral-halitosis-a-randomized-clinical-trial
#5
Seida Erovic Ademovski, Carina Mårtensson, G Rutger Persson, Stefan Renvert
AIM: To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral halitosis. MATERIALS AND METHODS: Forty-six adults with intra-oral halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral halitosis was evaluated at baseline, 3, and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2 S) and methyl mercaptan (MM) concentrations in exhaled air...
July 20, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28676903/estimated-prevalence-of-halitosis-a-systematic-review-and-meta-regression-analysis
#6
REVIEW
Manuela F Silva, Fábio R M Leite, Larissa B Ferreira, Natália M Pola, Frank A Scannapieco, Flávio F Demarco, Gustavo G Nascimento
OBJECTIVE: This study aims to conduct a systematic review to determine the prevalence of halitosis in adolescents and adults. METHODS: Electronic searches were performed using four different databases without restrictions: PubMed, Scopus, Web of Science, and SciELO. Population-based observational studies that provided data about the prevalence of halitosis in adolescents and adults were included. Additionally, meta-analyses, meta-regression, and sensitivity analyses were conducted to synthesize the evidence...
July 4, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28661108/-endoscopic-resection-of-zenker-diverticulum-a-single-center-experience
#7
Yuval Nachalon, Jacob Shvero
BACKGROUND: Zenker diverticulum (ZD) is a pseudodiverticulum and usually affects males in the 6th-9th decade of life, symptoms include dysphagia, regurgitation, chronic cough, aspiration, halitosis and weight loss. Surgery has been the mainstay treatment of symptomatic ZD and can be divided into external and intraluminal (endoscopic) techniques. METHODS: Charts of all patients who had endoscopic correction of ZD in a tertiary referral center in the last 5 years were retrieved...
June 2017: Harefuah
https://www.readbyqxmd.com/read/28512650/effect-of-antimicrobial-photodynamic-therapy-%C3%A2-and-laser-alone-as-adjunct-to-mechanical-debridement-in-the-management-of-halitosis-a-systematic-review
#8
Sergio Varela Kellesarian, Vanessa Ros Malignaggi, Abdulaziz A Al-Kheraif, Mansour Al-Askar, Michael Yunker, Fawad Javed
OBJECTIVE: The aim of the present study was to assess the efficacy of laser therapy (LT) and antimicrobial photodynamic therapy (aPDT) as adjunct to mechanical debridement (MD) on the management of halitosis. DATA SOURCES: In order to address the focused question "Is MD with adjunct LT and/or aPDT more effective in the management of halitosis compared with MD alone?" an electronic search without time or language restrictions was conducted up to January 2017 in indexed databases using the combination of different key words including photochemotherapy, lasers, light, photodynamic therapy, halitosis, and bad breath...
2017: Quintessence International
https://www.readbyqxmd.com/read/28479696/probable-benefits-of-green-tea-with-genetic-implications
#9
REVIEW
Kavita Singhal, Neerja Raj, Khushboo Gupta, Saurabh Singh
Tea is produced from the Camellia sinensis plant and can generally be divided into categories based on how they are processed. In general, green tea that is unfermented C. sinensis has been considered superior to black tea in health benefits. It contains a unique set of catechins that possess biological activity as antioxidant, anti-inflammatory and antiproliferative, which is potentially significant to the prevention and treatment of various forms of diseases. Oral cavity oxidative stress and inflammation, consequent cigarettes due to nicotine and acrolein, may be reduced in the presence of green tea polyphenols...
January 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28425827/efficacy-of-glycine-powder-air-polishing-combined-with-scaling-and-root-planing-in-the-treatment-of-periodontitis-and-halitosis-a-randomised-clinical-study
#10
Ayse Caygur, Mohammed R Albaba, Atilla Berberoglu, Hasan Guney Yilmaz
Introduction This study was performed to evaluate the clinical efficacy of using the Perio-Flow device (Electro Medical Systems, Nyon, Switzerland) adjunctively with mechanical instrumentation on periodontal parameters and halitosis. Materials and Methods Sixty patients who presented with a 4- to 6-mm probing pocket depth were recruited for the study. Patients were randomly assigned to scaling and root planing (SRP) or SRP + glycine powder air-polishing (GPAP). For both groups, the plaque index, gingival index, pocket depth, bleeding on probing, and clinical attachment level scores were recorded at baseline and 1 month...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28413322/improved-antimicrobial-effect-of-ginseng-extract-by-heat-transformation
#11
Peng Xue, Yang Yao, Xiu-Shi Yang, Jia Feng, Gui-Xing Ren
BACKGROUND: The incidence of halitosis has a prevalence of 22-50% throughout the world and is generally caused by anaerobic oral microorganisms, such as Fusobacterium nucleatum, Clostridium perfringens, and Porphyromonas gingivalis. Previous investigations on the structure-activity relationships of ginsenosides have led to contrasting results. Particularly, the antibacterial activity of less polar ginsenosides against halitosis-related bacteria has not been reported. METHODS: Crude saponins extracted from the Panax quinquefolius leaf-stem (AGS) were treated at 130°C for 3 h to obtain heat-transformed saponins (HTS)...
April 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28384990/primary-tuberculosis-of-nose-causing-bilateral-nasal-obstruction-and-halitosis-in-a-25-year-old-woman
#12
Leena Rajam, M Hari Kumar, Sabitha Hari Kumar
Primary or secondary nasal tuberculosis is rare and usually, it is considered as an extra pulmonary form of tuberculosis. Nasal tuberculosis infection may spread to maxillary palatal region by contagious or haematogenous route causing palatal perforation. In some instance, it may cause septal perforation with nasal obstruction which may give rise to halitosis. We report a case where, there was bilateral nasal mucosal involvement leading to severe nasal obstruction. This rare manifestation should be considered in areas where the disease is prevalent as delay in diagnosis and treatment could lead to serious and life threatening complications due to local spread from the nose to the para nasal sinuses and brain...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28353023/efficacy-of-gum%C3%A2-hydral-versus-biot%C3%A3-ne%C3%A2-oralbalance-mouthwashes-plus-gels-on-symptoms-of-medication-induced-xerostomia-a-randomized-double-blind-crossover-study
#13
Anna Greta Barbe, Yasmin Schmidt-Park, Stefanie Hamacher, Sonja Henny Maria Derman, Michael Johannes Noack
OBJECTIVES: The objective of this study is to determine the efficacy of GUM® Hydral versus Biotène® Oralbalance (both a mouthwash plus gel) on the subjective burden and clinical symptoms of patients with medication-induced xerostomia. MATERIALS AND METHODS: Subjects (N = 40) with medication-induced xerostomia (minimum 4/10 mm visual analog scale [VAS]) were randomized to treatment with GUM Hydral or Biotène Oralbalance mouthwash, both with gel, for 28 days...
March 28, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28326724/-research-progress-on-bisphosphonate-related-osteonecrosis-of-the-jaws
#14
REVIEW
Pan Jian, Wang Qizhang, Liu Jiyuan
Bisphosphonates (BPs), as potent drugs inhibiting bone resorption, have been widely used for treatment of several diseases. In recent years, dentists and oral and maxillofacial surgeons reported continuously increasing cases of bisphosphonate-related osteonecrosis of the jaws (BRONJ). This disease is clinically characterized by exposed bones, formation of sequestrum, pain, and halitosis. Provided that pathogenesis of BRONJ is unclear, effective treatments for this disease are currently unavailable. Thus, prevention plays an important role in the management of BRONJ...
February 1, 2017: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28304003/a-huge-thornwaldt-s-cyst-causing-hearing-loss-in-an-adult-patient
#15
Nazim Bozan, Yunus Feyyat Sakin, Pinar Kundi, Muzaffer Ari, Ferhat Bozkus
Nasopharynx (NP) is anatomically difficult to explore adequately. The pharyngeal bursa (PB) is a recess lined with respiratory epithelium along the posterior wall of the nasopharynx between the longus capitis muscles. If the opening through which the bursa drains into the nasopharynx becomes obstructed, a Thornwaldt's cyst (TC) might develop. Small-sized cysts are mostly asymptomatic, whereas large-sized cysts may lead to various nasal and otologic symptoms depending on their localization. In this report, we present a 71-year-old case with a huge TC who presented to our clinic with the complaints of snoring, nasal obstruction, periodic halitosis, postnasal drip, headache, and hearing loss in the left ear and underwent total excision of the cyst through transnasal endoscopy...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28291398/periodontal-therapy-in-dogs-using-bone-augmentation-products-marketed-for-veterinary-use
#16
Molly Angel
Periodontal disease is extremely common in companion animal practice. Patients presenting for a routine oral examination and prophylaxis may be found to have extensive periodontal disease and attachment loss. Vertical bone loss is a known sequela to periodontal disease and commonly involves the distal root of the mandibular first molar. This case report outlines two dogs presenting for oral examination and prophylaxis with general anesthesia. Both patients did not have any clinical symptoms of periodontal disease other than halitosis...
May 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28236205/influence-of-oral-probiotic-streptococcus-salivarius-k12-on-ear-and-oral-cavity-health-in-humans-systematic-review
#17
Katarina Zupancic, Valentina Kriksic, Irena Kovacevic, Dujo Kovacevic
Traditionally, probiotics are linked to the good health of the intestine and most clinical studies focus on that field. Evidence of oral probiotic use for ear and oral cavity disease prevention with impact on human health is limited. This work reviews existing studies and literature on Streptococcus salivarius K12 as an oral probiotic and effects of S. salivarius K12 on human ear and oral cavity human health. The studies were accessed via database searches: MEDLINE, PubMed, and Elsevier. The search included/focused on/encompassed publications from 2003 to 2016 with keywords related to K12 Streptococcus salivarius, bacteriocin-like inhibitory substances (BLIS) K12, probiotic K12 salivarius, and K12 probiotic health effects...
February 24, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28212110/the-impact-of-chewing-gum-on-halitosis-parameters-a-systematic-review
#18
Francisco Wilker Mustafa Gomes Muniz, Stephanie Anagnostopoulos Friedrich, Carina Folgearini Silveira, Cassiano Kuchenbecker Rösing
This study aimed to analyze the impact of chewing gum on halitosis parameters. Three databases were searched with the following focused question: 'Can chewing gum additionally reduce halitosis parameters, such as organoleptic scores and volatile sulfur compounds (VSC), when compared to a control treatment'? Controlled clinical trials presenting at least two halitosis measurements (organoleptic scores and/or VSC) were included. Ten studies were included, and different active ingredients were used. One study was performed using a chewing gum without any active ingredient...
February 17, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28033491/evaluation-of-carbohydrate-cysteamine-thiazolidines-as-pro-drugs-for-the-treatment-of-cystinosis
#19
Yasaman Ramazani, Elena N Levtchenko, Lambertus Van Den Heuvel, Ann Van Schepdael, Prasanta Paul, Ekaterina A Ivanova, Anna Pastore, Trina M Hartman, Neil P J Price
Cystinosis is a genetic disorder caused by malfunction of cystinosin and is characterized by accumulation of cystine. Cysteamine, the medication used in cystinosis, causes halitosis resulting in poor patient compliance. Halitosis is mainly caused by the formation of dimethylsulfide as the final product in the cysteamine metabolism pathway. We have synthesized carbohydrate-cysteamine thiazolidines, and hypothesized that the hydrolytic breakdown of cysteamine-thiazolidines can result in free cysteamine being released in target organs...
February 1, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28000643/pattern-of-presentation-and-outcome-of-routine-dental-interventions-in-patients-with-halitosis
#20
Olufemi Elijah Oyetola, Foluso John Owotade, Olawumi Adedoyin Fatusi, Saheed Olatunji
AIMS: The aims of this study were to describe the pattern of presentation of halitosis and to evaluate the success rate following routine dental intervention irrespective of the type of halitosis. PATIENTS AND METHODS: This cross-sectional study was conducted among sixty consecutive patients who presented in our Oral Diagnosis and Oral Medicine Clinic, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, on account of halitosis from May 2015 to April 2016...
October 2016: Nigerian Postgraduate Medical Journal
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