keyword
https://read.qxmd.com/read/38337989/genome-wide-association-study-gwas-for-identifying-snps-and-genes-related-to-phosphate-induced-phenotypic-traits-in-tomato-solanum-lycopersicum-l
#21
JOURNAL ARTICLE
Haroon Rashid Hakla, Shubham Sharma, Mohammad Urfan, Rushil Mandlik, Surbhi Kumawat, Prakriti Rajput, Bhubneshwari Khajuria, Rehana Chowdhary, Rupesh Deshmukh, Rajib Roychowdhury, Sikander Pal
Phosphate (P) is a crucial macronutrient for normal plant growth and development. The P availability in soils is a limitation factor, and understanding genetic factors playing roles in plant adaptation for improving P uptake is of great biological importance. Genome-wide association studies (GWAS) have become indispensable tools in unraveling the genetic basis of complex traits in various plant species. In this study, a comprehensive GWAS was conducted on diverse tomato ( Solanum lycopersicum L.) accessions grown under normal and low P conditions for two weeks...
February 5, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38284126/secreted-adamts-like-proteins-as-regulators-of-connective-tissue-function
#22
REVIEW
Nandaraj Taye, Charlene Redhead, Dirk Hubmacher
The extracellular matrix (ECM) determines functional properties of connective tissues through structural components, such as collagens, elastic fibers, or proteoglycans. The ECM also instructs cell behavior through regulatory proteins, including proteases, growth factors, and matricellular proteins, which can be soluble or tethered to ECM scaffolds. The secreted <u>a</u> <u>d</u>isintegrin <u>a</u>nd <u>m</u>etalloproteinase with <u>t</u>hrombo<u>s</u>pondin type 1 repeats/motifs-<u>l</u>ike (ADAMTSL) proteins constitute a family of regulatory ECM proteins that are related to ADAMTS proteases, but lack their protease domains...
January 29, 2024: American Journal of Physiology. Cell Physiology
https://read.qxmd.com/read/38271974/evaluation-of-accuracies-of-genomic-predictions-for-body-conformation-traits-in-korean-holstein
#23
JOURNAL ARTICLE
Md Azizul Haque, Mohammad Zahangir Alam, Asif Iqbal, Yun Mi Lee, Chang Gwon Dang, Jong Joo Kim
OBJECTIVE: This study aimed to assess the genetic parameters and accuracy of genomic predictions for twenty-four linear body conformation traits and overall conformation scores in Korean Holstein dairy cows. METHODS: A dataset of 2,206 Korean Holsteins was collected, and genotyping was performed using the Illumina Bovine 50K SNP chip. The traits investigated included body traits (stature, height at front end, chest width, body depth, angularity, body condition score, and locomotion), rump traits (rump angle, rump width, and loin strength), feet and leg traits (rear leg set, rear leg rear view, foot angle, heel depth, and bone quality), udder traits (udder depth, udder texture, udder support, fore udder attachment, front teat placement, front teat length, rear udder height, rear udder width, and rear teat placement), and overall conformation score...
January 20, 2024: Animal bioscience
https://read.qxmd.com/read/38258831/genetic-associations-with-acceleration-change-of-direction-jump-height-and-speed-in-english-academy-football-players
#24
JOURNAL ARTICLE
Alexander B T McAuley, David C Hughes, Loukia G Tsaprouni, Ian Varley, Bruce Suraci, Ben Bradley, Joseph Baker, Adam J Herbert, Adam L Kelly
McAuley, ABT, Hughes, DC, Tsaprouni, LG, Varley, I, Suraci, B, Bradley, B, Baker, J, Herbert, AJ, and Kelly, AL. Genetic associations with acceleration, change of direction, jump height, and speed in English academy football players. J Strength Cond Res 38(2): 350-359, 2024-High-intensity movements and explosive actions are commonly assessed during athlete development in football (soccer). Although many environmental factors underpin these power-orientated traits, research suggests that there is also a sizeable genetic component...
February 1, 2024: Journal of Strength and Conditioning Research
https://read.qxmd.com/read/38256802/genome-wide-association-study-for-agronomic-traits-in-gamma-ray-derived-mutant-kenaf-hibiscus-cannabinus-l
#25
JOURNAL ARTICLE
Woon Ji Kim, Baul Yang, Ye-Jin Lee, Jae Hoon Kim, Sang Hoon Kim, Joon-Woo Ahn, Si-Yong Kang, Seong-Hoon Kim, Jaihyunk Ryu
Kenaf ( Hibiscus cannabinus L.), in the Malvaceae family, is an important crop for not only fiber production, but also various other industrial materials. We performed phylogenetic analysis and a genome-wide association study (GWAS) of seven agronomic traits: days to flowering, plant height, fresh weight, dry weight, flower color, stem color, and leaf shape, using 96 kenaf genotypes, including gamma-irradiation-derived mutant lines. Genotypes were determined by genotyping-by-sequencing (GBS) and a total of 49,241 single-nucleotide polymorphisms (SNPs) were used in the analysis...
January 16, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38243199/signatures-of-local-adaptation-to-current-and-future-climate-in-phenology-related-genes-in-natural-populations-of-quercus-robur
#26
JOURNAL ARTICLE
Joanna Meger, Bartosz Ulaszewski, Daniel J Chmura, Jarosław Burczyk
BACKGROUND: Local adaptation is a key evolutionary process that enhances the growth of plants in their native habitat compared to non-native habitats, resulting in patterns of adaptive genetic variation across the entire geographic range of the species. The study of population adaptation to local environments and predicting their response to future climate change is important because of climate change. RESULTS: Here, we explored the genetic diversity of candidate genes associated with bud burst in pedunculate oak individuals sampled from 6 populations in Poland...
January 19, 2024: BMC Genomics
https://read.qxmd.com/read/38229016/single-nucleotide-polymorphism-snp19140160-a%C3%A2-%C3%A2-c-is-a-potential-breeding-locus-for-fast-growth-largemouth-bass-micropterus-salmoides
#27
JOURNAL ARTICLE
Jixiang Hua, Chunyi Zhong, Wenhua Chen, Jianjun Fu, Jian Wang, Qingchun Wang, Geyan Zhu, Yan Li, Yifan Tao, Maoyou Zhang, Yalun Dong, Siqi Lu, Wenting Liu, Jun Qiang
BACKGROUND: Largemouth bass (Micropterus salmoides) has significant economic value as a high-yielding fish species in China's freshwater aquaculture industry. Determining the major genes related to growth traits and identifying molecular markers associated with these traits serve as the foundation for breeding strategies involving gene pyramiding. In this study, we screened restriction-site associated DNA sequencing (RAD-seq) data to identify single nucleotide polymorphism (SNP) loci potentially associated with extreme growth differences between fast-growth and slow-growth groups in the F1 generation of a largemouth bass population...
January 16, 2024: BMC Genomics
https://read.qxmd.com/read/38227151/uncovering-the-genomic-regions-associated-with-yield-maintenance-in-rice-under-drought-stress-using-an-integrated-meta-analysis-approach
#28
JOURNAL ARTICLE
Parisa Daryani, Nazanin Amirbakhtiar, Jahad Soorni, Fatemeh Loni, Hadi Darzi Ramandi, Zahra-Sadat Shobbar
The complex trait of yield is controlled by several quantitative trait loci (QTLs). Given the global water deficit issue, the development of rice varieties suitable for non-flooded cultivation holds significant importance in breeding programs. The powerful approach of Meta-QTL (MQTL) analysis can be used for the genetic dissection of complicated quantitative traits. In the current study, a comprehensive MQTL analysis was conducted to identify consistent QTL regions associated with drought tolerance and yield-related traits under water deficit conditions in rice...
January 16, 2024: Rice
https://read.qxmd.com/read/38187330/association-of-genetic-polymorphisms-of-edn1-gene-and-endothelin-1-level-in-patients-with-type-2-diabetes-mellitus-in-the-jordanian-population
#29
JOURNAL ARTICLE
Ahmed O Maslat, Omar M Al-Mahmood, Nahla M Al Khawaja, Ramadan Al-Shdefat
Endothelin-1 (ET-1) is one of the most potent vasoconstrictors, encoded by the endothelin-1 (EDN 1) gene. It has been shown to play an important role in different diseases including Diabetes Mellitus (DM). Various single nucleotide polymorphisms (SNPs) in the EDN 1 gene are related to microvascular complications of type 2 diabetes mellitus (T2DM) such as retinopathy, neuropathy and nephropathy. This study aims to determine the association between two selected EDN 1 gene polymorphisms (rs2071942 G > A, rs5370 G > T) and T2DM in the Jordanian population, also to measure the level of ET-1 in T2DM...
January 15, 2024: Heliyon
https://read.qxmd.com/read/38184855/genetic-and-brain-similarity-independently-predict-childhood-anthropometrics-and-neighborhood-socioeconomic-conditions
#30
JOURNAL ARTICLE
Andreas Dahl, Espen M Eilertsen, Sara F Rodriguez-Cabello, Linn B Norbom, Anneli D Tandberg, Esten Leonardsen, Sang Hong Lee, Eivind Ystrom, Christian K Tamnes, Dag Alnæs, Lars T Westlye
Linking the developing brain with individual differences in clinical and demographic traits is challenging due to the substantial interindividual heterogeneity of brain anatomy and organization. Here we employ an integrative approach that parses individual differences in both cortical thickness and common genetic variants, and assess their effects on a wide set of childhood traits. The approach uses a linear mixed model framework to obtain the unique effects of each type of similarity, as well as their covariance...
January 4, 2024: Developmental Cognitive Neuroscience
https://read.qxmd.com/read/38170788/nad-precursors-and-bile-acid-sequestration-treat-preclinical-refractory-environmental-enteric-dysfunction
#31
JOURNAL ARTICLE
Atika Malique, Shengxiang Sun, Kanta Chandwe, Beatrice Amadi, Talin Haritunians, Umang Jain, Brian D Muegge, Jennifer Frein, Yo Sasaki, Amanda Foster, Chad E Storer, Emebet Mengesha, Justin Kern, Dermot P B McGovern, Richard D Head, Paul Kelly, Ta-Chiang Liu
Environmental enteric dysfunction (EED) is a diffuse small bowel disorder associated with poor growth, inadequate responses to oral vaccines, and nutrient malabsorption in millions of children worldwide. We identify loss of the small intestinal Paneth and goblet cells that are critical for innate immunity, reduced villous height, increased bile acids, and dysregulated nicotinamide adenine dinucleotide (NAD+ ) synthesis signaling as potential mechanisms underlying EED and which also correlated with diminished length-for-age z score...
January 3, 2024: Science Translational Medicine
https://read.qxmd.com/read/38166623/genomic-evaluation-for-breeding-and-genetic-management-in-cordia-africana-a-multipurpose-tropical-tree-species
#32
JOURNAL ARTICLE
Kedra M Ousmael, Eduardo P Cappa, Jon K Hansen, Prasad Hendre, Ole K Hansen
BACKGROUND: Planting tested forest reproductive material is crucial to ensure the increased resilience of intensively managed productive stands for timber and wood product markets under climate change scenarios. Single-step Genomic Best Linear Unbiased Prediction (ssGBLUP) analysis is a cost-effective option for using genomic tools to enhance the accuracy of predicted breeding values and genetic parameter estimation in forest tree species. Here, we tested the efficiency of ssGBLUP in a tropical multipurpose tree species, Cordia africana, by partial population genotyping...
January 2, 2024: BMC Genomics
https://read.qxmd.com/read/38166525/genome-wide-association-study-of-agronomic-traits-related-to-nitrogen-use-efficiency-in-henan-wheat
#33
JOURNAL ARTICLE
Zaicheng Zhang, Chaojun Peng, Weigang Xu, Yan Li, Xueli Qi, Mingzhong Zhao
BACKGROUND: Nitrogen use efficiency (NUE) is closely related to crop yield and nitrogen fertilizer application rate. Although NUE is susceptible to environments, quantitative trait nucleotides (QTNs) for NUE in wheat germplasm populations have been rarely reported in genome-wide associated study. RESULTS: In this study, 244 wheat accessions were phenotyped by three NUE-related traits in three environments and genotyped by 203,224 SNPs. All the phenotypes for each trait were used to associate with all the genotypes of these SNP markers for identifying QTNs and QTN-by-environment interactions via 3VmrMLM...
January 2, 2024: BMC Genomics
https://read.qxmd.com/read/38149679/identification-of-ago2-and-plec-genes-polymorphisms-in-hu-sheep-and-their-relationship-with-body-size-traits
#34
JOURNAL ARTICLE
Jia Liu, Wenxin Zheng, Weimin Wang, Xiaobin Yang, Yongliang Huang, Panpan Cui, Zongwu Ma, Xiwen Zeng, Rui Zhai, Xiuxiu Weng, Weiwei Wu, Xiaoxue Zhang
The body size traits are major traits in livestock, which intuitively displays the development of the animal's bones and muscles. This study used PCR amplification, Sanger sequencing, KASPar genotyping, and quantitative real-time reverse transcription PCR (qRT-PCR) to analyze the Single-nucleotide polymorphism and expression characteristics of Argonaute RISC catalytic component 2 ( AGO2 ) and Plectin ( PLEC ) genes in Hu sheep. Two intron mutations were found in Hu sheep, which were AGO2 g.51700 A > C and PLEC g...
December 27, 2023: Animal Biotechnology
https://read.qxmd.com/read/38142253/identification-of-a-novel-snp-in-the-mir172-binding-site-of-q-homoeolog-ap2l-d5-is-associated-with-spike-compactness-and-agronomic-traits-in-wheat-triticum-aestivum-l
#35
JOURNAL ARTICLE
Victoria Zeng, Cristobal Uauy, Yi Chen
This study found that the compact spike locus of ANK-15 is on chromosome 5D instead of 2B. We have identified a new allele of AP2L-D5 as the candidate causal polymorphism. Spike architecture is a key determinant of wheat yield, a crop which supports much of the human diet but whose yield gains are stagnating. Spike architecture mutants offer opportunities to identify genetic factors contributing to inflorescence development. Here, we investigate the locus underlying the compact spike phenotype of mutant line ANK-15 by conducting mRNA-sequencing and genetic mapping using ANK-15 and its non-compact spike near-isogenic line Novosibirskaya 67 (N67)...
December 23, 2023: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://read.qxmd.com/read/38136962/functional-characterization-of-the-almstn2-gene-and-its-association-with-growth-traits-in-the-yellowfin-seabream-acanthopagrus-latus-hottuyn-1782
#36
JOURNAL ARTICLE
Jianyi Guo, Huayang Guo, Chuanghua Chen, Fangzhao Yu, Baosuo Liu, Nan Zhang, Lin Xian, Zhiping Luo, Wen Liu, Kecheng Zhu, Dianchang Zhang
Myostatin (mstn), also known as GDF8, is a growth and differentiation factor of the transforming growth factor-β (TGF-β) superfamily and plays a key inhibitory effect in the regulation of skeletal muscle development and growth in vertebrates. In the present study, to comprehend the role of the mstn2 gene of the yellowfin seabream Acanthopagrus latus ( Almstn2b ), the genomic sequence of Almstn2b is 2359 bp, which encodes 360 amino acids and is composed of three exons and two introns, was obtained...
November 27, 2023: Genes
https://read.qxmd.com/read/38135043/genome-wide-association-study-of-age-at-puberty-and-its-co-variances-with-fertility-and-stature-in-growing-and-lactating-holstein-friesian-dairy-cattle
#37
JOURNAL ARTICLE
M A Stephen, C R Burke, N Steele, J E Pryce, S Meier, P R Amer, C V C Phyn, D J Garrick
Reproductive performance is a key determinant of cow longevity in a pasture-based, seasonal dairy system. Unfortunately, direct fertility phenotypes such as inter-calving interval or pregnancy rate tend to have low heritabilities and occur relatively late in an animal's life. In contrast, age at puberty (AGEP) is a moderately heritable, early-in-life trait, that may be estimated using an animal's age at first measured elevation in blood plasma progesterone (AGEP4) concentrations. Understanding the genetic architecture of AGEP4 in addition to genetic relationships between AGEP4 and fertility traits in lactating cows is important, as is its relationship with body size in the growing animal...
December 20, 2023: Journal of Dairy Science
https://read.qxmd.com/read/38111387/inheritance-of-body-size-and-ultrasound-carcass-traits-in-yearling-anatolian-buffalo-calves
#38
JOURNAL ARTICLE
Samet Çinkaya, Mustafa Tekerli
The body size and ultrasound carcass traits are related to the growth and muscling of animals. These characters promise future improvement through genetic selection in animal breeding. In breeding programs, knowing the (co)variance components serves to reveal the performance differences among animals and detection of suitable traits for selection. The research was carried out with 313 Anatolian buffalo calves born in 2019 at 36 farm operations. The least-square means for body weight (BW), wither height (WH), rump height (RH), body length (BL), chest width (CW), hip width (HW), chest circumference (CC), cannon-bone circumference (CBC), longissimus muscle area (LMA), longissimus muscle depth (LMD), and subcutaneous fat thickness (SFT) in yearling calves were 175...
2023: Archives animal breeding
https://read.qxmd.com/read/38110866/ridge-regression-and-deep-learning-models-for-genome-wide-selection-of-complex-traits-in-new-mexican-chile-peppers
#39
JOURNAL ARTICLE
Dennis N Lozada, Karansher Singh Sandhu, Madhav Bhatta
BACKGROUND: Genomewide prediction estimates the genomic breeding values of selection candidates which can be utilized for population improvement and cultivar development. Ridge regression and deep learning-based selection models were implemented for yield and agronomic traits of 204 chile pepper genotypes evaluated in multi-environment trials in New Mexico, USA. RESULTS: Accuracy of prediction differed across different models under ten-fold cross-validations, where high prediction accuracy was observed for highly heritable traits such as plant height and plant width...
December 18, 2023: BMC genomic data
https://read.qxmd.com/read/38110604/the-polymorphism-of-the-ovine-insulin-like-growth-factor-2-igf2-gene-and-their-associations-with-growth-related-traits-in-tibetan-sheep
#40
JOURNAL ARTICLE
Xianlin Zhao, Jinyun Yan, Hanping Chu, Zhenling Wu, Wendi Li, Qing Zhang, Yu Zhang, Yanmin Guo, Zhaobin Fan
In the current study, the role of the ovine IGF2 as a potential candidate gene was investigated as though marker-assisted selection in Chinese Tibetan sheep. The Sanger DNA sequencing method explored five single nucleotide polymorphisms (SNPs) in 5'UTR of the ovine IGF2 gene (C15640T, G15801A, G15870A, C15982G and G15991A) in Chinese Tibetan sheep. The frequencies of four SNPs were within the Hardy-Weinberg Equilibrium (chi-square test) except C15982G. The statistical analysis indicated that the C15640T and G15801A were significantly associated with body height, body length, chest circumference, and body weight (P < 0...
December 18, 2023: Tropical Animal Health and Production
keyword
keyword
4671
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.