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https://www.readbyqxmd.com/read/29165689/oculomotor-disturbances-in-patients-with-chronic-nonspecific-spinal-pain
#1
Ruth Ruscheweyh, Antonia Fritz, Thomas Eggert, Shahnaz-Christina Azad, Andreas Straube
Objective: There is increasing evidence that the cerebellum has a role in pain processing. The present study investigates whether chronic pain patients, who are likely to have altered pain processing, exhibit signs of subtle cerebellar dysfunction. We used oculomotor tasks to assess dysfunction of the associated neuronal networks, including the cerebellum. Methods: Thirty patients with chronic nonspecific spinal pain and 30 age- and sex-matched controls were enrolled...
November 18, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29164724/intraoperative-localization-of-the-subthalamic-nucleus-using-long-latency-somatosensory-evoked-potentials
#2
Carlos Trenado, Saskia Elben, Lena Friggemann, Stefan Jun Groiss, Jan Vesper, Alfons Schnitzler, Lars Wojtecki
BACKGROUND: Target localization for deep brain stimulation (DBS) is a challenging step that determines not only the correct placement of stimulation electrodes, but also influences the success of the DBS procedure as reflected in the desired clinical outcome of a patient. OBJECTIVE: We report on the feasibility of DBS target localization in the subthalamic nucleus (STN) by long-latency somatosensory evoked potentials (LL-SSEPs) (>40 msec) in Parkinson's disease (PD) patients...
November 22, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29164702/window-door-opening-mediated-bedroom-ventilation-and-its-impact-on-sleep-quality-of-healthy-young-adults
#3
A K Mishra, A M van Ruitenbeek, M G L C Loomans, H S M Kort
This work examined window/door opening as means of bedroom ventilation and the consequent effect upon occupants' sleep, using data from 17 healthy volunteers. Bedroom CO2 level, temperature, and relative humidity were measured over 5 days, for two cases: open window or door (internal, bedroom door), and closed window and door. Participant filled questionnaires and sleep diary provided subjective measure of sleep quality. Actigraphy objectively monitored the participants during sleep. Additionally, a FlexSensor, placed under pillows of participants, detected movement during sleep...
November 21, 2017: Indoor Air
https://www.readbyqxmd.com/read/29164609/who-benefits-from-adolescent-sleep-interventions-moderators-of-treatment-efficacy-in-a-randomized-controlled-trial-of-a-cognitive-behavioral-and-mindfulness-based-group-sleep-intervention-for-at-risk-adolescents
#4
Matthew J Blake, Laura M Blake, Orli Schwartz, Monika Raniti, Joanna M Waloszek, Greg Murray, Julian G Simmons, Elizabeth Landau, Ronald E Dahl, Dana L McMakin, Paul Dudgeon, John Trinder, Nicholas B Allen
BACKGROUND: The aim of this study was to test moderators of therapeutic improvement in an adolescent cognitive-behavioral and mindfulness-based group sleep intervention. Specifically, we examined whether the effects of the program on postintervention sleep outcomes were dependent on participant gender and/or measures of sleep duration, anxiety, depression, and self-efficacy prior to the interventions. METHOD: Secondary analysis of a randomized controlled trial conducted with 123 adolescent participants (female = 59...
November 22, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29164571/assessment-of-mismatch-negativity-and-p300-response-in-patients-with-disorders-of-consciousness
#5
X-Y Wang, H-Y Wu, H-T Lu, T-T Huang, H Zhang, T Zhang
OBJECTIVE: To evaluate changes in mismatch negativity (MMN) and P300 response in vegetative state (VS) and minimally conscious state (MCS) patients before and after treatment, and their value for prediction of prognosis. PATIENTS AND METHODS: Event-related potentials (ERPs), performed on 11 patients classified as VS (n = 6) or MCS (n = 5), and five healthy participants (i.e., control group). We performed a six months telephone follow-up to monitor changes in consciousness recovery...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164485/music-listening-and-stress-in-daily-life-a-matter-of-timing
#6
Alexandra Linnemann, Mario Wenzel, Jennifer Grammes, Thomas Kubiak, Urs M Nater
PURPOSE: Despite increasing evidence suggesting that music listening in daily life has stress-reducing effects, studies mostly rely on subjective, retrospective data on music listening. Thus, the temporal dynamics underlying the stress-reducing effect of music listening remain unclear. Therefore, we aimed to examine the temporal dynamics of the associations between stress and music listening by assessing subjective and objective data on music in daily life. DESIGN: An exploratory Ambulatory Assessment study examining a total of 60 participants (37 women), aged 18 to 34 years (M = 22...
November 21, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29164341/mathematical-models-of-hiv-latency
#7
Alison L Hill
Viral latency is a major barrier to curing HIV infection with antiretroviral therapy, and consequently, for eliminating the disease globally. The establishment, maintenance, and potential clearance of latent infection are complex dynamic processes and can be best understood and described with the help of mathematical models. Here we review the use of viral dynamics models for HIV, with a focus on applications to the latent reservoir. Such models have been used to explain the multiphasic decay of viral load during antiretroviral therapy, the early seeding of the latent reservoir during acute infection and the limited inflow during treatment, the dynamics of viral blips, and the phenomenon of posttreatment control...
November 22, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/29163964/occult-liver-disease-burden-analysis-from-a-large-general-practitioners-database
#8
Andrea Martini, Elena Ceranto, Angelo Gatta, Paolo Angeli, Patrizia Pontisso
Background: Cirrhosis represents the end stage of chronic liver disease, characterized by high mortality and morbidity. The prevalence of liver disease is difficult to assess, given its clinical latency up to the late stage. Objective: We aimed to assess the prevalence of unrecognized chronic liver disease and cirrhosis using surrogate indicators from medical records of family physicians. Methods: Medical records of 139,104 subjects, collected from 99 family physicians of the Veneto region, were used...
November 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29163615/assessing-the-pathogenic-ability-of-ralstonia-pseudosolanacearum-ralstonia-solanacearum-phylotype-i-from-ornamental-rosa-spp-plants
#9
Napoleon N A Tjou-Tam-Sin, Jeroen L J van de Bilt, Marcel Westenberg, Peggy P M A Gorkink-Smits, N Marco Landman, Maria Bergsma-Vlami
Ralstonia pseudosolanacearum (Ralstonia solanacearum phylotype I) isolates found in stunted, yellowing, and wilted ornamental rose (Rosa spp.) were assessed for their pathogenic ability in two rose cultivars (cv. "Armando" and cv. "Red Naomi") and in four solanaceous crops: tomato (Solanum lycopersicum cv. "Money Maker"), tobacco (Nicotiana tabacum cv. "White Burley"), eggplant (Solanum melongena cv. "Black Beauty") and sweet pepper (Capsicum annum cv. "Yolo Wonder"). Significant differences were observed in susceptibility between the two rose cultivars as well as between the two modes of inoculation performed...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29163433/what-goes-around-comes-around-hsv-1-replication-in-monocyte-derived-dendritic-cells
#10
REVIEW
Linda Grosche, Mirko Kummer, Alexander Steinkasserer
HSV-1 is a very successful human pathogen, known for its high sero-prevalence and the ability to infect a wide range of different cell types, including dendritic cells (DCs). As very potent antigen-presenting cells DCs play an important role in the induction of antiviral immune responses and therefore represent a strategic target for viral-mediated immune escape mechanisms. It is known that HSV-1 completes its gene expression profile in immature as well as in mature DCs, while lytic infection is only found in immature DCs (iDCs)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29163348/intermediate-latency-evoked-potentials-of-multimodal-cortical-vestibular-areas-galvanic-stimulation
#11
Stefan Kammermeier, Arun Singh, Kai Bötzel
Introduction: Human multimodal vestibular cortical regions are bilaterally anterior insulae and posterior opercula, where characteristic vestibular-related cortical potentials were previously reported under acoustic otolith stimulation. Galvanic vestibular stimulation likely influences semicircular canals preferentially. Galvanic stimulation was compared to previously established data under acoustic stimulation. Methods: 14 healthy right-handed subjects, who were also included in the previous acoustic potential study, showed normal acoustic and galvanic vestibular-evoked myogenic potentials...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29163320/morpheme-based-reading-and-writing-in-spanish-children-with-dyslexia
#12
Paz Suárez-Coalla, Cristina Martínez-García, Fernando Cuetos
It has been well documented that morphemic structure (roots and affixes) have an impact in reading, but effects seem to depend on the reading experience of readers and lexical characteristics of the stimuli. Specifically, it has been reported that morphemes constitute reading units for developing readers and children with dyslexia when they encounter a new word. In addition, recent studies have stated that the effect of morphology is also present in spelling, as morphological information facilitates spelling accuracy and influences handwriting times...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29163235/electrophysiological-anomalies-in-face-name-memory-encoding-in-young-binge-drinkers
#13
Rocío Folgueira-Ares, Fernando Cadaveira, Socorro Rodríguez Holguín, Eduardo López-Caneda, Alberto Crego, Paula Pazo-Álvarez
A growing body of evidence indicates that the intake of large amounts of alcohol during one session may have structural and functional effects on the still-maturing brains of young people. These effects are particularly pronounced in prefrontal and hippocampal regions, which appear to be especially sensitive to the neurotoxic effects of alcohol. However, to date, few studies have used the event-related potentials (ERPs) technique to analyze the relationship between binge drinking (BD) and associative memory...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29163075/pauses-in-striatal-cholinergic-interneurons-what-is-revealed-by-their-common-themes-and-variations
#14
REVIEW
Yan-Feng Zhang, Stephanie J Cragg
Striatal cholinergic interneurons, the so-called tonically active neurons (TANs), pause their firing in response to sensory cues and rewards during classical conditioning and instrumental tasks. The respective pause responses observed can demonstrate many commonalities, such as constant latency and duration, synchronous occurrence in a population of cells, and coincidence with phasic activities of midbrain dopamine neurons (DANs) that signal reward predictions and errors. Pauses can however also show divergent properties...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/29163062/difference-in-perseverative-errors-during-a-visual-attention-task-with-auditory-distractors-in-alpha-9-nicotinic-receptor-subunit-wild-type-and-knock-out-mice
#15
Pascal Jorratt, Paul H Delano, Carolina Delgado, Alexies Dagnino-Subiabre, Gonzalo Terreros
The auditory efferent system is a neural network that originates in the auditory cortex and projects to the cochlear receptor through olivocochlear (OC) neurons. Medial OC neurons make cholinergic synapses with outer hair cells (OHCs) through nicotinic receptors constituted by α9 and α10 subunits. One of the physiological functions of the α9 nicotinic receptor subunit (α9-nAChR) is the suppression of auditory distractors during selective attention to visual stimuli. In a recent study we demonstrated that the behavioral performance of alpha-9 nicotinic receptor knock-out (KO) mice is altered during selective attention to visual stimuli with auditory distractors since they made less correct responses and more omissions than wild type (WT) mice...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29163017/electrical-neuroimaging-of-music-processing-reveals-mid-latency-changes-with-level-of-musical-expertise
#16
Clara E James, Mathias S Oechslin, Christoph M Michel, Michael De Pretto
This original research focused on the effect of musical training intensity on cerebral and behavioral processing of complex music using high-density event-related potential (ERP) approaches. Recently we have been able to show progressive changes with training in gray and white matter, and higher order brain functioning using (f)MRI [(functional) Magnetic Resonance Imaging], as well as changes in musical and general cognitive functioning. The current study investigated the same population of non-musicians, amateur pianists and expert pianists using spatio-temporal ERP analysis, by means of microstate analysis, and ERP source imaging...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29162502/vagus-nerve-magnetic-modulation-facilitates-dysphagia-recovery-in-patients-with-stroke-involving-the-brainstem-a-proof-of-concept-study
#17
Wang-Sheng Lin, Chen-Liang Chou, Miao-Hsiang Chang, Yuh-Mei Chung, Fu-Gong Lin, Po-Yi Tsai
BACKGROUND & AIMS: Stroke involving the brainstem (SBS) causes severe oropharyngeal dysphagia (OD). Research on the therapeutic efficacy of vagus nerve modulation (VNM) by using repetitive transcranial magnetic stimulation (rTMS) in SBS patients with OD has been limited thus far. We aimed to assess the effect of VNM by using rTMS in improving swallowing function after SBS. METHOD: We conducted a sham-controlled, double-blinded, parallel pilot study in 28 SBS patients with OD randomly allocated to a real rTMS group (n = 13; TMSreal) or a sham group (n = 15; TMSsham)...
November 7, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29162039/experiences-and-wishes-of-women-regarding-systemic-aspects-of-midwifery-care-in-germany-a-qualitative-study-with-focus-groups
#18
Elke Mattern, Susanne Lohmann, Gertrud M Ayerle
BACKGROUND: Knowledge of pregnant women's and mothers' viewpoints on midwifery care is crucial for its appropriate delivery and research. In Germany, comprehensive research to more fully understand women's needs in pregnancy, labour, birth and the postpartum period until weaning is lacking. International studies provide some knowledge of women's expectations, their choices, and subjective criteria indicating good midwifery care. METHODS: This study explores pregnant women's and mothers' experiences, needs and wishes regarding systemic aspects of midwifery care (access, availability, choices, model of midwifery care; maternity care in the healthcare system)...
November 21, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29161976/a-new-approach-for-the-determination-of-ecap-thresholds
#19
Sebastian Hoth, Philipp Spitzer, Mark Praetorius
BACKGROUND: Electrically evoked compound action potentials (ECAPs) of the auditory nerve are routinely recorded for testing the cochlear implant integrity and its functional connection to the auditory system. The response thresholds derived from ECAP recordings are widely used as a helpful guide in the fitting of the dynamic range of electric stimulation, although they may not always predict the behavioral thresholds of individuals well. Conventionally, this threshold is based on the identification of a minimum N peak and maximum P peak and linear extrapolation of the resulting amplitude growth function (AGF)...
November 22, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/29161899/how-long-should-routine-eeg-be-recorded-to-get-relevant-information
#20
Hannah Doudoux, Kristina Skaare, Thomas Geay, Philippe Kahane, Jean L Bosson, Cécile Sabourdy, Laurent Vercueil
OBJECTIVE: The optimal duration of routine EEG (rEEG) has not been determined on a clinical basis. This study aims to determine the time required to obtain relevant information during rEEG with respect to the clinical request. METHOD: All rEEGs performed over 3 months in unselected patients older than 14 years in an academic hospital were analyzed retrospectively. The latency required to obtain relevant information was determined for each rEEG by 2 independent readers blinded to the clinical data...
March 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
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