keyword
https://read.qxmd.com/read/38635843/a-model-study-of-teaching-method-reform-of-computer-laboratory-course-integrating-internet-of-things-technology
#1
JOURNAL ARTICLE
Xiao Zhou, Ledan Qian, Haider Aziz, Marvin White
The Internet of Things (IoT) is gradually changing the way teaching and learning take place in on-campus programs. In particular, face capture services improve student concentration to create an efficient classroom atmosphere by using face recognition algorithms that support end devices. However, reducing response latency and executing face analysis services effectively in real-time is still challenging. For this reason, this paper proposed a pedagogical model of face recognition for IoT devices based on edge computing (TFREC)...
2024: PloS One
https://read.qxmd.com/read/38635661/transcriptome-analysis-of-burkitt-lymphoma-cells-treated-with-anti-convulsant-drugs-that-are-inhibitors-of-epstein-barr-virus-lytic-reactivation
#2
JOURNAL ARTICLE
Kelly L Gorres, David M Reineke, George Miller
Herpesviruses have two distinct life cycle stages, latency and lytic replication. Epstein-Barr virus (EBV), a gamma-herpesvirus, establishes latency in vivo and in cultured cells. Cell lines harboring latent EBV can be induced into the lytic cycle by treatment with chemical inducing agents. In the Burkitt lymphoma cell line HH514-16 the viral lytic cycle is triggered by butyrate, a histone deacetylase (HDAC) inhibitor. Butyrate also alters expression of thousands of cellular genes. However, valproic acid (VPA), another HDAC inhibitor with global effects on cellular gene expression blocks EBV lytic gene expression in Burkitt lymphoma cell lines...
2024: PloS One
https://read.qxmd.com/read/38635409/evaluation-of-masseteric-vestibular-evoked-myogenic-potentials-in-patients-with-migraine
#3
JOURNAL ARTICLE
Nida Tas Elibol, Meliha Başöz Behmen, Şengül Terlemez, Özlem Konukseven
PURPOSE: Masseter vestibular evoked myogenic potentials (mVEMP) involve the connection between the vestibular complex and trigeminal nerve nuclei. Given the theory that migraine is caused by increased activation of the trigeminal nerve, it is believed that mVEMP responses may have influenced in migraine patients. METHOD: The study included 20 individuals with migraine and 20 healthy controls. Latency, amplitude, and interaural amplitude asymmetry ratio of mVEMP responses recorded in migraine patients were compared with control group...
April 18, 2024: American Journal of Audiology
https://read.qxmd.com/read/38634723/the-role-of-epstein-barr-virus-in-autoimmune-and-autoinflammatory-diseases
#4
REVIEW
Abdul Hamid Borghol, Elio R Bitar, Aya Hanna, Georges Naim, Elias A Rahal
Epstein-Barr Virus (EBV), a dsDNA herpesvirus, is believed to play a significant role in exacerbating and potentially triggering autoimmune and autoinflammatory maladies. Around 90% of the world is infected with the virus, which establishes latency within lymphocytes. EBV is also known to cause infectious mononucleosis, a self-limited flu-like illness, in adolescents. EBV is often reactivated and it employs several mechanisms of evading the host immune system. It has also been implicated in inducing host immune dysfunction potentially resulting in exacerbation or triggering of inflammatory processes...
April 18, 2024: Critical Reviews in Microbiology
https://read.qxmd.com/read/38634540/electrically-evoked-auditory-brainstem-responses-in-deaf-children-with-cochlear-nerve-canal-stenosis
#5
JOURNAL ARTICLE
Wenyun Luo, Hanyu Zhu, Li Chen, Kai Shi, Xiaoyan Hou, Jingwu Sun, Jiaqiang Sun, Xiaotao Guo
BACKGROUND: Deaf children with cochlear nerve canal stenosis (CNCs) are always considered poor candidates for cochlear implantation. OBJECTIVES: To investigate the function of the peripheral auditory pathway in deaf children with CNCs, as revealed by the electrically evoked auditory brainstem response (EABR), and postoperative cochlear implants (CIs) outcomes. MATERIALS AND METHODS: Thirteen children with CNCs and 13 children with no inner ear malformations (IEMs) who received CIs were recruited...
April 18, 2024: Acta Oto-laryngologica
https://read.qxmd.com/read/38634228/the-test-retest-reliability-of-non-navigated-transcranial-magnetic-stimulation-tms-measures-of-corticospinal-pathway-excitability-early-after-stroke
#6
JOURNAL ARTICLE
Kathryn C Collins, Allan B Clark, Valerie M Pomeroy, Niamh C Kennedy
PURPOSE: Motor evoked potential (MEP) characteristics are potential biomarkers of whether rehabilitation interventions drive motor recovery after stroke. The test-retest reliability of Transcranial Magnetic Stimulation (TMS) measurements in sub-acute stroke remains unclear. This study aims to determine the test-retest reliability of upper limb MEP measures elicited by non-neuronavigated transcranial magnetic stimulation in sub-acute-stroke. METHODS: In two identical data collection sessions, 1-3 days apart, TMS measures assessed: motor threshold (MT), amplitude, latency (MEP-L), silent period (SP), recruitment curve slope in the biceps brachii (BB), extensor carpi radialis (ECR), and abductor pollicis brevis (APB) muscles of paretic and non-paretic upper limbs...
April 18, 2024: Disability and Rehabilitation
https://read.qxmd.com/read/38633776/genetic-risk-health-associated-lifestyle-and-risk-of-early-onset-total-cancer-and-breast-cancer
#7
Yin Zhang, Sara Lindström, Peter Kraft, Yuxi Liu
IMPORTANCE: Early-onset cancer (diagnosed under 50 years of age) is associated with aggressive disease characteristics and its rising incidence is a global concern. The association between healthy lifestyle and early-onset cancer and whether it varies by common genetic variants is unknown. OBJECTIVE: To examine the associations between genetic risk, lifestyle, and risk of early-onset cancers. DESIGN SETTING AND PARTICIPANTS: We analyzed a prospective cohort of 66,308 white British participants who were under age 50 and free of cancer at baseline in the UK Biobank...
April 6, 2024: medRxiv
https://read.qxmd.com/read/38633538/astrocyte-activation-in-hindlimb-somatosensory-cortex-contributes-to-electroacupuncture-analgesia-in-acid-induced-pain
#8
JOURNAL ARTICLE
Qing Ye, Jie Li, Wen-Jing Ren, Ying Zhang, Tao Wang, Patrizia Rubini, Hai-Yan Yin, Peter Illes, Yong Tang
BACKGROUND: Several studies have confirmed the direct relationship between extracellular acidification and the occurrence of pain. As an effective pain management approach, the mechanism of electroacupuncture (EA) treatment of acidification-induced pain is not fully understood. The purpose of this study was to assess the analgesic effect of EA in this type of pain and to explore the underlying mechanism(s). METHODS: We used plantar injection of the acidified phosphate-buffered saline (PBS; pH 6...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38632676/a-clinical-framework-for-video-head-impulse-testing-and-vestibular-evoked-myogenic-potential-assessments-in-primary-school-aged-children
#9
JOURNAL ARTICLE
Ruth Van Hecke, Frederik J A Deconinck, Maya Danneels, Ingeborg Dhooge, Bo Uzeel, Leen Maes
OBJECTIVES: This study aimed to offer normative data and age trends of an age-appropriate vestibular test protocol in a large group (n = 140) of school-aged children (6 to 13 years old) as well as to provide a practical and clinical framework for accurate performance and interpretation of vestibular test results in this specific age group. DESIGN: The typically developing participants (mean age of 9.51 ± 2.04 years) were recruited to provide a representative group of 20 children for each of the seven age groups that were composed of children aged from 6 to 13 years in 1-year intervals...
April 18, 2024: Ear and Hearing
https://read.qxmd.com/read/38632350/improved-data-quality-and-statistical-power-of-trial-level-event-related-potentials-with-bayesian-random-shift-gaussian-processes
#10
JOURNAL ARTICLE
Dustin Pluta, Beniamino Hadj-Amar, Meng Li, Yongxiang Zhao, Francesco Versace, Marina Vannucci
Studies of cognitive processes via electroencephalogram (EEG) recordings often analyze group-level event-related potentials (ERPs) averaged over multiple subjects and trials. This averaging procedure can obscure scientifically relevant variability across subjects and trials, but has been necessary due to the difficulties posed by inference of trial-level ERPs. We introduce the Bayesian Random Phase-Amplitude Gaussian Process (RPAGP) model, for inference of trial-level amplitude, latency, and ERP waveforms. We apply RPAGP to data from a study of ERP responses to emotionally arousing images...
April 17, 2024: Scientific Reports
https://read.qxmd.com/read/38631941/electrophysiological-changes-on-laryngeal-motor-neuropathways-cause-voice-disorders-for-postradiotherapy-patients-with-nasopharyngeal-carcinoma
#11
JOURNAL ARTICLE
Cui He, Libing Guo, Mingfen Zheng, Hong Peng, Xuhui Zhang, Changhe Fan, Xiangdong Zhao, Pinggui Gong, Zeyi Deng, Guang Xu, Cuijie Chen
OBJECTIVE: This study explored electrophysiological changes in the laryngeal motor neuropathway and determined whether lesions in the laryngeal motor cortex (LMC) and its descending tract contribute to voice deterioration and peripheral nerve palsy in patients with nasopharyngeal carcinoma (NPC) postradiotherapy (RT). STUDY DESIGNS: Prospective cohort study. METHODS: Twenty-two patients with NPC at 2 to 4years post-RT (8 female and 14 male), 22 patients with NPC at 8 to 10years post-RT (8 female and 14 male), and 22 healthy individuals (9 female and 13 male) were selected to test their magnetic evoked potentials (MEP), motor nerve conduction, and voice quality using transcranial magnetic stimulation, laryngeal electromyography, and the XION DiVAS acoustic analysis software...
April 16, 2024: Journal of Voice
https://read.qxmd.com/read/38631635/imidacloprid-reduces-the-mating-success-of-males-in-bumblebees
#12
JOURNAL ARTICLE
Xing Chen, Yuhao Wang, Yao Zhou, Feiran Wang, Jian Wang, Xudong Yao, Muhammad Imram, Shudong Luo
Bumblebees play a vital role in both natural and agricultural environments, however there has been a noticeable decline in their populations. Pesticides, particularly neonicotinoids, are widely regarded as a substantial contributing factor to the decline in bumblebee populations, as evidenced by the detrimental impacts documented across many stages of their life cycle. Mating is vital for the population maintenance of bumblebees. Nevertheless, there is a scarcity of research conducted on the effects of pesticides on the mating process...
April 15, 2024: Science of the Total Environment
https://read.qxmd.com/read/38631619/rechallenge-in-idiosyncratic-drug-induced-liver-injury-an-analysis-of-cases-in-two-large-prospective-registries-according-to-existing-definitions
#13
JOURNAL ARTICLE
J M Pinazo-Bandera, H Niu, Alvarez-Alvarez, Medina-Caliz, E Del Campo-Herrera, A Ortega-Alonso, M Robles-Díaz, N Hernández, R Paraná, Nunes, M Girala, F Bessone, M I Lucena, R J Andrade, M García Cortés
INTRODUCTION: Data on positive rechallenge in idiosyncratic drug-induced liver injury (DILI) are scarce. We aim to analyse the clinical presentation, outcome and drugs associated with positive rechallenge in two DILI registries. METHODS: Cases from the Spanish and Latin American DILI registries were included. Demographics, clinical characteristics and outcome of cases with positive rechallenge according to CIOMS/RUCAM and current definitions were analysed. RESULTS: Of 1,418 patients with idiosyncratic DILI, 58 cases had positive rechallenge (4...
April 15, 2024: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/38631074/understanding-the-variability-of-the-electrophysiologic-laryngeal-adductor-reflex
#14
JOURNAL ARTICLE
Mirela V Simon, Seward B Rutkove, Long Ngo, Corey R Fehnel, Alvin S Das, Todd Sarge, Somnath Bose, Magdy Selim, Sandeep Kumar
OBJECTIVE: The laryngeal adductor reflex (LAR) is vital for airway protection and can be electrophysiologically obtained under intravenous general anesthesia (IGA). This makes the electrophysiologic LAR (eLAR) an important tool for monitoring of the vagus nerves and relevant brainstem circuitry during high-risk surgeries. We investigated the intra-class variability of normal and expected abnormal eLAR. METHODS: Repeated measures of contralateral R1 (cR1) were performed under IGA in 58 patients...
March 26, 2024: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://read.qxmd.com/read/38630803/precise-cortical-contributions-to-sensorimotor-feedback-control-during-reactive-balance
#15
JOURNAL ARTICLE
Scott Boebinger, Aiden Payne, Giovanni Martino, Kennedy Kerr, Jasmine Mirdamadi, J Lucas McKay, Michael Borich, Lena Ting
The role of the cortex in shaping automatic whole-body motor behaviors such as walking and balance is poorly understood. Gait and balance are typically mediated through subcortical circuits, with the cortex becoming engaged as needed on an individual basis by task difficulty and complexity. However, we lack a mechanistic understanding of how increased cortical contribution to whole-body movements shapes motor output. Here we use reactive balance recovery as a paradigm to identify relationships between hierarchical control mechanisms and their engagement across balance tasks of increasing difficulty in young adults...
April 17, 2024: PLoS Computational Biology
https://read.qxmd.com/read/38630459/fast-saccades-to-faces-during-the-feedforward-sweep
#16
JOURNAL ARTICLE
Alison Campbell, James W Tanaka
Saccadic choice tasks use eye movements as a response method, typically in a task where observers are asked to saccade as quickly as possible to an image of a prespecified target category. Using this approach, face-selective saccades have been observed within 100 ms poststimulus. When taking into account oculomotor processing, this suggests that faces can be detected in as little as 70 to 80 ms. It has therefore been suggested that face detection must occur during the initial feedforward sweep, since this latency leaves little time for feedback processing...
April 1, 2024: Journal of Vision
https://read.qxmd.com/read/38630381/short-post-injection-seizure-duration-is-associated-with-reduced-power-of-ictal-brain-perfusion-spect-to-lateralize-the-seizure-onset-zone
#17
JOURNAL ARTICLE
Amir Karimzadeh, Kian Baradaran-Salimi, Berthold Voges, Ivayla Apostolova, Thomas Sauvigny, Michael Lanz, Susanne Klutmann, Stefan Stodieck, Philipp T Meyer, Ralph Buchert
BACKGROUND: The aim of this study was to assess the impact of the post-injection electrical seizure duration on the identification of the seizure onset zone (SOZ) in ictal brain perfusion SPECT in presurgical evaluation of drug-resistant epilepsy. METHODS: 176 ictal SPECT performed with 99m Tc-HMPAO (n = 140) or -ECD (n = 36) were included retrospectively. Visual interpretation of the SPECT images (together with individual MRI and statistical hyperperfusion maps) with respect to lateralization (right, left, none) and localization (temporal, frontal, parietal, occipital) of the SOZ was performed by 3 independent readers...
April 17, 2024: EJNMMI Research
https://read.qxmd.com/read/38629851/histomorphologic-biomechanical-and-functional-analysis-in-mandibular-osteogenesis-induced-by-external-distraction
#18
JOURNAL ARTICLE
Antonio Fuente-Del-Campo, Daniel Reyes Cureño
The induced bone generation procedure (osteogenic distraction [OD]) is frequently used in cases of jaw deformities in patients with, hemifacial microsomia, mandibular hypoplasia, and so on. This study was undertaken to provide criteria to perform this procedure. The authors evaluated the effects of various parameters using OD to determine the optimal variables. Sixty distractors were placed in 30 canine subjects who then underwent OD after appropriate osteotomy. The procedures were performed during varying latency periods, distraction periods, distraction rate distance, and the consolidation period...
April 17, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38629490/effect-of-dynamic-binaural-beats-on-sleep-quality-a-proof-of-concept-study-with-questionnaire-and-biosignals
#19
JOURNAL ARTICLE
Hwa-Ah-Ni Lee, Woo-Jin Lee, Seong-Uk Kim, Hyunji Kim, Minkyu Ahn, Jeong-Hee Kim, Do-Won Kim, Chang-Ho Yun, Han-Jeong Hwang
Binaural beat (BB) has been investigated as a potential modality to enhance sleep quality. In this study, we introduce a new form of BB, referred to as dynamic BB (DBB), which incorporates dynamically changing carrier frequency differences between the left and right ears. Specifically, the carrier frequency of the right ear varied between 100 and 103 Hz over a period, while the left ear remained fixed at 100 Hz, yielding a frequency difference range of 0 to 3 Hz. The objective of this study was to examine the effect of DBB on sleep quality...
April 17, 2024: Sleep
https://read.qxmd.com/read/38629395/study-on-gamma-sensory-flicker-for-insomnia
#20
JOURNAL ARTICLE
Yakun Liu, Xinrong Li, Sha Liu, Tailing Liang, Yan Wu, Xiaopan Wang, Ying Li, Yong Xu
OBJECTIVES: Insomnia has been the subject of much systematic research because it is a risk factor for a variety of diseases. There is some evidence that gamma sensory stimulation therapy has also been demonstrated to improve sleep quality for people with Alzheimer's disease. However, it is unclear whether this method is effective for treating insomnia. The principal objective of this project was to investigate the efficacy and safety of gamma sensory flicker in improving the sleep quality of insomnia patients...
April 17, 2024: International Journal of Neuroscience
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