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https://www.readbyqxmd.com/read/28943247/space-time-epidemiology-of-crimean-congo-hemorrhagic-fever-cchf-in-iran
#1
Mohsen Ahmadkhani, Ali Asghar Alesheikh, Sahar Khakifirouz, Mostafa Salehi-Vaziri
Iran, as an endemic country of Crimean-Congo hemorrhagic fever (CCHF), has been suffering from severe health issues and substantial economic burdens imposed by the disease. We analyzed monthly and yearly spatial and temporal distributions of CCHF to better understand the epidemiology of the disease in Iran. A cross-sectional survey was performed on 1027 recorded cases between 2000 and 2014. Global Moran's I analysis was applied to statistically evaluate the spatial pattern of the disease. Additionally, spatial and space-time scan statistics were used to study the presence of possible spatial and space-time hotspots...
September 18, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28942662/-ophthalmological-symptoms-of-measles-and-their-treatment
#2
Mihály Végh, András Hári-Kovács, Hans-Walter Roth, Andrea Facskó
Measles, caused by the Morbilli virus, is a highly (about 95 %) contagious disease affecting primarily children, but without proper immunisation, adults can also be infected. The leading symptoms of the disease are high fever that presents after an incubation period of 9-10 days and the red rash that begins several days after the fever starts. Beyond specific generalized symptoms, measles may have ocular symptoms. The most commonly occurring conjunctivitis, the so-called "red eye symptom", is not characteristic only for measles infection, however, by taking the generalized symptoms it can suggest the diagnosis at the beginning of the disease...
October 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28942479/tumor-necrosis-factor-associated-periodic-syndrome-in-adults
#3
REVIEW
Sharika Gopakumar Menon, Petros Efthimiou
Tumor necrosis factor-associated periodic syndrome is an autoinflammatory disorder classified under hereditary periodic fever syndromes. Mutations in the tumor necrosis factor receptor contribute to tumor necrosis factor-associated periodic syndrome. Decreased shedding of receptors and increased mitochondrial reactive oxygen species production leading to elevated proinflammatory cytokines are documented. Inflammation in various organs is hallmark of tumor necrosis factor-associated periodic syndrome and manifests as spiking fever, abdominal pain, conjunctivitis and polyserositis in adults...
September 23, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28941816/risk-factors-associated-with-milk-fever-occurrence-in-grazing-dairy-cattle
#4
A Saborío-Montero, B Vargas-Leitón, J J Romero-Zúñiga, J M Sánchez
The aim of this study was to determine risk factors associated with milk fever (MF) occurrence in Costa Rican grazing dairy cattle. A total of 69,870 cows from 126 dairy herds were included in the study. Data were collected in the Veterinary Automated Management and Production Control Program software by the Population Medicine Research Program of the Veterinary Medicine School, National University of Costa Rica, from 1985 to 2014. To determine the risk factors for MF, 2 logistic regression mixed models were evaluated...
September 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28940983/changes-in-trends-and-impact-of-testing-for-influenza-in-infants-with-fever-under-90-days-of-age
#5
Suji Kim, Hye Min Moon, Joon Kee Lee, Kyuyol Rhie, Ki Wook Yoon, Eun Hwa Choi, Hoan Jong Lee, Hyunju Lee
BACKGROUND: Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing. METHODS: Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015...
September 22, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28938257/childhood-visceral-leishmaniasis-distinctive-features-and-diagnosis-of-a-re-emerging-disease-an-11-year-experience-from-a-tertiary-referral-center-in-athens-greece
#6
Panagiotis Krepis, Adamantia Krepi, Ioanna Argyri, Anastasios Aggelis, Alexandra Soldatou, Maria Tsolia
BACKGROUND: Visceral leishmaniasis (VL) remains a public health issue in Greece. The aim of this study was to describe the clinical and epidemiological characteristics of pediatric VL in our region as well as to evaluate the laboratory findings and the diagnostic techniques that are applied. METHODS: We retrospectively reviewed the medical records of all children diagnosed with VL in an 11-year period at a tertiary public hospital in the region of Athens. Demographic features, clinical information and laboratory findings were accessed...
September 20, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28937843/emergency-department-visits-for-postpartum-complications
#7
Erin Christine Brousseau, Valery Danilack, Fei Cai, Kristen A Matteson
INTRODUCTION: Most estimates of the prevalence and types of postpartum complications are based on hospital readmissions. However, using hospital readmissions (which occurs in only 1%-2% of postpartum women) is problematic as it fails to include women with postpartum complications assessed in the office or emergency department (ED). We utilized data from a cohort of women evaluated in an ED setting to better characterize complications experienced by women in the postpartum period. MATERIALS AND METHODS: We performed a retrospective analysis of all postpartum visits to the ED at a tertiary care women's hospital over 6 months...
September 22, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28937791/web-based-surveillance-of-illness-in-childcare-centers
#8
Natalie Schellpfeffer, Abaigeal Collins, David C Brousseau, Emily T Martin, Andrew Hashikawa
School absenteeism is an inefficient and unspecific metric for measuring community illness and does not provide surveillance during summertime. Web-based biosurveillance of childcare centers may represent a novel way to efficiently monitor illness outbreaks year-round. A web-based biosurveillance program ( sickchildcare.org ) was created and implemented in 4 childcare centers in a single Michigan county. Childcare providers were trained to report sick children who required exclusion or had parent-reported absences due to illness...
September 22, 2017: Health Security
https://www.readbyqxmd.com/read/28934952/post-market-outcome-of-an-extract-of-traditional-cretan-herbs-on-upper-respiratory-tract-infections-a-pragmatic-prospective-observational-study
#9
Marilena Anastasaki, Antonios Bertsias, Stergios A Pirintsos, Elias Castanas, Christos Lionis
BACKGROUND: The beneficial effects of traditional herbs of Crete, Greece for the treatment of upper respiratory tract infections have been reported in observational and laboratory studies. Following a published, double blind, randomized, placebo controlled trial, this study aimed to assess the effectiveness of an extract of three Cretan herbs on the treatment of upper respiratory tract infections, upon its market release. METHODS: An observational study was conducted in Heraklion, Crete, Greece...
September 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28934933/medicine-use-practices-in-management-of-symptoms-of-acute-upper-respiratory-tract-infections-in-children-%C3%A2-12%C3%A2-years-in-kampala-city-uganda
#10
Moses Ocan, Mary Aono, Clare Bukirwa, Emmanuel Luyinda, Cathy Ochwo, Elastus Nsambu, Stella Namugonza, Joseph Makoba, Enock Kandaruku, Hannington Muyende, Aida Nakawunde
BACKGROUND: Medicines are commonly accessed and used for management of illness in children without a prescription. This potentially increases the risk of unwanted treatment outcomes. We investigated medicine use practices in management of symptoms of acute upper respiratory tract infections among children (≤12 years) in households in Nakawa division, Kampala city. METHODS: This was a cross-sectional study conducted among 390 randomly selected children. Data on use of medicines in children (≤12 years) during recent episode of acute upper respiratory tract infection was collected from their care takers using an interviewer administered questionnaire...
September 21, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28931535/risk-of-hospitalisation-with-fever-following-menb-vaccination-self-controlled-case-series-analysis
#11
Heather Murdoch, Lynn Wallace, Jennifer Bishop, Chris Robertson, J Claire Cameron
OBJECTIVE: To investigate a possible association between fever admissions and 4 component Meningococcal B (4CMenB). DESIGN: 4CMenB is given at 8 and 16 weeks in the first year of life. Self-controlled case series using linked routinely collected healthcare data, where the risk period was the 3 days immediately following receipt of a vaccine dose. PATIENTS: Children aged under 1 year in Scotland preintroduction and postintroduction of 4CMenB vaccine (pre-September 2014 to August 2015 and post-September 2015 to June 2016)...
October 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28931025/the-clinical-and-microbiological-characteristics-of-enteric-fever-in-cambodia-2008-2015
#12
Laura M F Kuijpers, Thong Phe, Chhun H Veng, Kruy Lim, Sovann Ieng, Chun Kham, Nizar Fawal, Laetitia Fabre, Simon Le Hello, Erika Vlieghe, François-Xavier Weill, Jan Jacobs, Willy E Peetermans
BACKGROUND: Enteric fever remains a major public health problem in low resource settings and antibiotic resistance is increasing. In Asia, an increasing proportion of infections is caused by Salmonella enterica serovar Paratyphi A, which for a long time was assumed to cause a milder clinical syndrome compared to Salmonella enterica serovar Typhi. METHODOLOGY: A retrospective chart review study was conducted of 254 unique cases of blood culture confirmed enteric fever who presented at a referral adult hospital in Phnom Penh, Cambodia between 2008 and 2015...
September 20, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28929009/meta-analysis-of-biomarkers-for-severe-dengue-infections
#13
Kuan-Meng Soo, Bahariah Khalid, Siew-Mooi Ching, Chau Ling Tham, Rusliza Basir, Hui-Yee Chee
BACKGROUND: Dengue viral infection is an acute infection that has the potential to have severe complications as its major sequela. Currently, there is no routine laboratory biomarker with which to predict the severity of dengue infection or monitor the effectiveness of standard management. Hence, this meta-analysis compared biomarker levels between dengue fever (DF) and severe dengue infections (SDI) to identify potential biomarkers for SDI. METHODS: Data concerning levels of cytokines, chemokines, and other potential biomarkers of DF, dengue hemorrhagic fever, dengue shock syndrome, and severe dengue were obtained for patients of all ages and populations using the Scopus, PubMed, and Ovid search engines...
2017: PeerJ
https://www.readbyqxmd.com/read/28926322/vitamin-d-status-serum-lipid-concentrations-and-vitamin-d-receptor-vdr-gene-polymorphisms-in-familial-mediterranean-fever
#14
Turan Turhan, Halef Okan Doğan, Nihal Boğdaycioğlu, Nilnur Eyerci, Ahmet Omma, İsmail Sari, Ahmet Yeşilyurt, Yaşar Karaaslan
Vitamin D (VitD) is critical for the regulation of inflammatory processes, and VitD deficiency has been linked to several chronic inflammatory disorders. We aimed to investigate the concentrations of serum 25(OH)D3, lipid parameters, and three known VDR polymorphisms (BsmI, FokI, and TaqI) in patients with Familial Mediterranean fever (FMF), an autosomal recessive autoinflammatory disease. The study included 123 FMF patients and 105 controls. A total of 38 patients were in acute attacks at the time of investigation...
September 18, 2017: Bosnian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/28924723/sixteen-chinese-pediatric-brucellosis-patients-onset-of-fever-in-non-epidemic-areas-and-8-developed-with-osteoarticular-involvement
#15
Xinning Wang, Yuchun Yan, Fengqi Wu, Gaixiu Su, Shengnan Li, Xinyu Yuan, Jianming Lai, Zhixuan Zhou
The purpose of this study is to summarize the manifestations, diagnosis, differential diagnosis, and treatment of childhood brucellosis in non-epidemic areas of China. A retrospective review of 16 admitted children patients with brucella's disease who were diagnosed of brucellosis during the period from 2011 to 2016 was performed. Diagnostic criteria, clinical presentations, and outcomes were recorded. The most common symptom was fever. Osteoarticular involvement was found in 50% of the patients. They were infected by contacting with infected animals or consuming of unpasteurized milk or meat of sheep or goats, also...
September 19, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28919592/the-study-on-the-lives-and-health-conditions-of-internees-in-santo-thomas-camp-of-philippines-based-on-mcanlis-s-the-war-in-manila-1941-1945
#16
Jueyeon Lee, Youngsoo Cho
When Japan invaded the Philippines, two missionary dentists (Dr. McAnlis and Dr. Boots) who were forced to leave Korea were captured and interned in the Santo Thomas camp in Manila. Japan continued to bombard and plunder the Philippines in the wake of the Pacific War following the Great East Asia policy, leading to serious inflation and material deficiency. More than 4,000 Allied citizens held in Santo Thomas camp without basic food and shelter. Santo Thomas Camp was equipped with the systems of the Japanese military medical officers and Western doctors of captivity based on the Geneva Conventions(1929)...
August 2017: Ŭi Sahak
https://www.readbyqxmd.com/read/28905403/infectious-disease-prediction-with-kernel-conditional-density-estimation
#17
Evan L Ray, Krzysztof Sakrejda, Stephen A Lauer, Michael A Johansson, Nicholas G Reich
Creating statistical models that generate accurate predictions of infectious disease incidence is a challenging problem whose solution could benefit public health decision makers. We develop a new approach to this problem using kernel conditional density estimation (KCDE) and copulas. We obtain predictive distributions for incidence in individual weeks using KCDE and tie those distributions together into joint distributions using copulas. This strategy enables us to create predictions for the timing of and incidence in the peak week of the season...
September 14, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28903411/efficacy-and-safety-of-re-du-ning-injection-in-the-treatment-of-seasonal-influenza-results-from-a-randomized-double-blinded-multicenter-oseltamivir-controlled-trial
#18
Yu Liu, Wei Mu, Wei Xiao, Bao-Lin Wei, Lan Wang, Xin-Qiao Liu, Xu-Dong Xiong, Xiao-Min Huang, Ye-Qing Zhang, Hai-Ming Chen, Feng-Jie Yan, Yu-Ping Tan, Yu-Hong Huang
OBJECTIVE: To assess the efficacy and safety of RDNI in the treatment of seasonal influenza. RESULTS: 1575 participants were screened and 229 completed the study and had a RT-PCR laboratory confirmation of influenza virus infection. Fever alleviation time was 2 and 6 hours, and fever clearance time was 27 and 47 in RDNI and oseltamivir, with significant difference between two groups. Total scores of influenza symptoms descended more in RDNI than oseltamivir on day 2 and day 3...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902271/-clinical-and-epidemiological-characterization-of-chikungunya-fever-in-mexico
#19
Carolina Garay-Morán, Juan Francisco Román-Pedroza, Irma López-Martínez, José Cruz Rodríguez-Martínez, Cuitláhuac Ruiz-Matus, Pablo Kuri-Morales, José Alberto Díaz-Quiñonez
On 6 December 2013, the Pan American Health Organization (PAHO) and the World Health Organization (WHO) reported confirmation of the first two cases of indigenous transmission of chikungunya fever (CHIK) in the Region of the Americas on the island of Sint Maarten (Netherlands Antilles). For the period 2013-2014, a total of 25 627 confirmed autochthonous cases were distributed in 43 countries, with Mexico reporting 155 cases in five states. Information on cases of CHIK in Mexico was obtained from the database of the General Directorate of Epidemiology (Ministry of Health of Mexico)...
August 21, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28893243/impact-of-pharmacy-worker-training-and-deployment-on-access-to-essential-medicines-for-children-under-five-in-malawi-a-cluster-quasi-experimental-evaluation
#20
Joseph B Babigumira, Solomon J Lubinga, Alisa M Jenny, Erin Larsen-Cooper, Jessica Crawford, Charles Matemba, Andy Stergachis
BACKGROUND: Poor access to essential medicines is common in many low- and middle-income countries, partly due to an insufficient and inadequately trained workforce to manage the medicines supply chain. We conducted a prospective impact evaluation of the training and deployment of pharmacy assistants (PAs) to rural health centers in Malawi. METHODS: A quasi-experimental design was used to compare access to medicines in two districts where newly trained PAs were deployed to health centers (intervention) and two districts with no trained PAs at health centers (comparison)...
September 11, 2017: BMC Health Services Research
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