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https://www.readbyqxmd.com/read/29764789/eosinophilic-otitis-media-treated-with-anti-ige-monoclonal-antibodies-and-a-bone-conduction-implant
#1
Young Eun Han, Yong Seok Kang, Younhoon Cho, Moo Kyun Park
Eosinophilic otitis media (EOM) are intractable otitis media characterized by highly viscous secretions containing eosinophils in the middle ear. They are resistant to conventional medication and surgery. This condition occurs primarily in patients with bronchial asthma or allergic rhinitis and is often complicated by rhinosinusitis. Systemic and topical steroid therapies are effective treatments. However, long-term steroid therapy is often limited by a high risk of serious adverse effects. The use of topical steroids and otorrhea are bothersome when wearing hearing aids...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29747060/acoustic-stimulation-on-the-round-window-for-active-middle-ear-implants
#2
Kiwoong Seong, Kyuyup Lee, Sunil Puria, Jin-Ho Cho
Many clinical reports have discussed the effectiveness of stimulating the ear's round window (RW) with a tool to mitigate conductive and mixed hearing loss. The RW is one of the two openings from the middle ear into the inner ear. Various methods have been proposed to construct a highly efficient, easily implanted, and reliable RW transducer. Devices, however, such as floating mass transducers, have difficulty establishing proper contact without some degree of bone incision around the RW. Additionally, vibration energy may not be fully transmitted to the cochlea, but instead will be spread through the soft tissue around the transducer...
May 2, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29733111/physical-outcome-measures-for-conductive-and-mixed-hearing-loss-treatment-a-systematic-review
#3
M L Johansson, J R Tysome, P Hill-Feltham, W E Hodgetts, A Ostevik, B J McKinnon, P Monksfield, R Sockalingam, T Wright
BACKGROUND: The number of potential options for rehabilitation of patients with conductive or mixed hearing loss is continually expanding. To be able to inform patients and other stakeholders there is a need to identify and develop patient-centred outcomes for treatment of hearing loss. OBJECTIVE OF REVIEW: To identify outcome measures in the physical core area used when reporting the outcome after treatment of conductive and mixed hearing loss in adult patients...
May 7, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29728102/stenting-the-eustachian-tube-to-treat-chronic-otitis-media-a-feasibility-study-in-sheep
#4
Friederike Pohl, Robert A Schuon, Felicitas Miller, Andreas Kampmann, Eva Bültmann, Christian Hartmann, Thomas Lenarz, Gerrit Paasche
BACKGROUND: Untreated chronic otitis media severely impairs quality of life in affected individuals. Local destruction of the middle ear and subsequent loss of hearing are common sequelae, and currently available treatments provide limited relief. Therefore, the objectives of this study were to evaluate the feasibility of the insertion of a coronary stent from the nasopharynx into the Eustachian tube in-vivo in sheep and to make an initial assessment of its positional stability, tolerance by the animal, and possible tissue reactions...
May 4, 2018: Head & Face Medicine
https://www.readbyqxmd.com/read/29723597/hybrid-ear-cubes-for-local-controlled-dexamethasone-delivery-to-the-inner-ear
#5
M Gehrke, J Verin, D Gnansia, G Tourrel, M Risoud, C Vincent, F Siepmann, J Siepmann
A new type of miniaturized implants for local controlled drug delivery to the inner ear is proposed: Hybrid Ear Cubes. They are composed of two main parts: (i) a cylinder, which is placed into a tiny hole (<0.4 mm) drilled into (or close to) the oval (or round) window, and (ii) a cuboid, which is placed into the middle ear. The drug is released at a pre-programmed rate into the perilymph: (i) via the cylindrical part of the implant, which is in direct contact with this liquid, and (ii) via diffusion from the cuboid through the oval/round window...
April 30, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29708489/fmri-as-a-preimplant-objective-tool-to-predict-children-s-postimplant-auditory-and-language-outcomes-as-measured-by-parental-observations
#6
Aniruddha K Deshpande, Lirong Tan, Long J Lu, Mekibib Altaye, Scott K Holland
BACKGROUND: The trends in cochlear implantation candidacy and benefit have changed rapidly in the last two decades. It is now widely accepted that early implantation leads to better postimplant outcomes. Although some generalizations can be made about postimplant auditory and language performance, neural mechanisms need to be studied to predict individual prognosis. PURPOSE: The aim of this study was to use functional magnetic resonance imaging (fMRI) to identify preimplant neuroimaging biomarkers that predict children's postimplant auditory and language outcomes as measured by parental observation/reports...
May 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29698958/vibrant-soundbridge-implantation-floating-mass-transducer-coupled-with-the-stapes-head-and-embedded-in-fat
#7
Qingsong Liu, Guodong Feng, Yingying Shang, Suju Wang, Zhiqiang Gao
Subtotal petrosectomy may be performed for refractory chronic middle ear diseases, such as massive cholesteatoma or recurrent otitis media. It involves permanent obliteration of the operative cavity, thus precluding the chance to restore conductive hearing via traditional inertial ossicular prostheses. The Vibrant Soundbridge (VSB) is an alternative option for hearing rehabilitation. Vibrant energy is delivered into the inner ear via a floating mass transducer (FMT), which can be coupled with any part of the middle ear acoustic transmission structure...
April 26, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29697586/benefits-of-bimodal-hearing-with-cochlear-and-middle-ear-implants-preliminary-results-in-four-patients
#8
Hyun Jin Lee, Sung Huhn Kim, In Seok Moon, Jinsei Jung, Jeon Mi Lee, Jae Young Choi
OBJECTIVE: Conventional hearing aids have some limitations in overcoming a large air-bone gap or in cases of severe high-frequency hearing loss. The authors aimed to evaluate the benefit of a new bimodal hearing configuration combining cochlear implantation (CI) and middle ear implant (MEI) in patients with severe mixed conductive and ski-slope hearing loss. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENTS: Four patients with severe to profound hearing loss, who underwent CI in one ear and MEI in the other, were enrolled...
April 24, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29678325/does-hearing-in-response-to-soft-tissue-stimulation-involve-skull-vibrations-a-within-subject-comparison-between-skull-vibration-magnitudes-and-hearing-thresholds
#9
Shai Chordekar, Ronen Perez, Cahtia Adelman, Haim Sohmer, Liat Kishon-Rabin
Hearing can be elicited in response to bone as well as soft-tissue stimulation. However, the underlying mechanism of soft-tissue stimulation is under debate. It has been hypothesized that if skull vibrations were the underlying mechanism of hearing in response to soft-tissue stimulation, then skull vibrations would be associated with hearing thresholds. However, if skull vibrations were not associated with hearing thresholds, an alternative mechanism is involved. In the present study, both skull vibrations and hearing thresholds were assessed in the same participants in response to bone (mastoid) and soft-tissue (neck) stimulation...
April 3, 2018: Hearing Research
https://www.readbyqxmd.com/read/29664726/measurement-of-the-electrically-evoked-stapedial-reflex-response-with-wideband-acoustic-reflectance-measurement
#10
Jace Wolfe, Rene Gifford, Erin Schafer
BACKGROUND: The electrically evoked stapedial reflex threshold (ESRT) has been shown to be a good predictor of upper stimulation level for cochlear implant recipients. Previous research has shown that the ESRT may be recorded at lower stimulation levels and with a higher incidence of success with the use of higher frequency probe tones (e.g., 678 and 1000 Hz) relative to the use of the conventional 226-Hz probe tone. Research has also shown that the acoustic reflex may be recorded at lower stimulus levels with the use of wideband reflectance when compared to the acoustic reflex threshold recorded with a conventional acoustic immittance measurement...
April 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29664723/the-value-of-electrically-evoked-stapedius-reflex-in-determining-the-maximum-comfort-level-of-a-cochlear-implant
#11
Kelly Cristina Lira de Andrade, Lilian Ferreira Muniz, Pedro de Lemos Menezes, Silvio da Silva Caldas Neto, Aline Tenório Lins Carnaúba, Mariana de Carvalho Leal
BACKGROUND: One of the most important steps for good user performance with a cochlear implant (CI) is activation and programming, aimed at determining the dynamic range. In adults, current levels are determined by psychophysical measures. In babies, small children, or individuals with multiple disorders, this procedure requires techniques that may provide inconsistent responses because of auditory inexperience or the age of the child, making it a very difficult process that demands the collaboration of both the patient and the family...
April 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29620546/comparison-of-cochlear-duct-length-between-the-saudi-and-non-saudi-populations
#12
Alaa Alanazi, Farid Alzhrani
BACKGROUND: There are no data on cochlear duct lengths (CDL) among Middle East populations. OBJECTIVES: The main aims of this study were to estimate the average CDL in the Saudi population and to compare it with the reported CDL in other regions/ethnic groups outside the Middle East. DESIGN: Retrospective study. SETTING: Tertiary otolaryngology head and neck surgery center. SUBJECTS AND METHODS: Temporal bone CT scans were reviewed to determine CDL...
March 2018: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/29607572/a-clinical-guidance-to-dfna22-drawn-from-a-korean-cohort-study-with-an-autosomal-dominant-deaf-population-a-retrospective-cohort-study
#13
Bong Jik Kim, Jin Hee Han, Hye-Rim Park, Min Young Kim, Ah Reum Kim, Seung-Ha Oh, Woong-Yang Park, Doo Yi Oh, Seungmin Lee, Byung Yoon Choi
BACKGROUND: The MYO6 gene, if altered, can cause non-syndromic hearing loss (NSHL) either in autosomal dominant (AD) (DFNA22) or recessive form. This study identified MYO6 variants in the cohort of Korean AD NSHL families and investigated the audiological phenotypes of DFNA22 to suggest clinical guides for the counseling of DFNA22. METHODS: Retrospective cohort study was performed on 81 AD NSHL families in two hospitals. Among them, five families (SH21, SB60, SB247, SB290, and SB305) segregating with MYO6 variant were genetically and clinically assessed...
April 1, 2018: Journal of Gene Medicine
https://www.readbyqxmd.com/read/29555078/active-middle-ear-implants
#14
Luis Lassaletta, Isabel Sánchez-Cuadrado, Juan Manuel Espinosa, Ángel Batuecas, Carlos Cenjor, María José Lavilla, Laura Cavallé, Alicia Huarte, Faustino Nuñez, Manuel Manrique, Ángel Ramos, Carlos de Paula, Elisa Gil-Carcedo
Active middle ear implants are surgically implanted prosthesis, which intend to stimulate the ossicular chain or the inner ear fluids through the oval or round windows. These implants may be useful for the treatment of certain patients with sensorineural hearing loss as well as for conductive or mixed hearing loss. This clinical guide attempts to summarize the current knowledge concerning the basic characteristics and indications of the most commonly used middle ear implants, including Vibrant Soundbrige (Med-el, Innsbruck), Carina (Cochlear, Australia), and CodacsTM ...
March 17, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29553839/bimodal-benefit-for-cochlear-implant-listeners-with-different-grades-of-hearing-loss-in-the-opposite-ear
#15
Ulrich Hoppe, Thomas Hocke, Frank Digeser
OBJECTIVE: To determine speech perception in quiet and noise of adult cochlear implant listeners retaining a hearing aid contralaterally. Second, to investigate the influence of contralateral hearing thresholds and speech perception on bimodal hearing. PATIENTS AND METHODS: Sentence recognition with hearing aid alone, cochlear implant alone and bimodally at 6 months after cochlear implantation were assessed in 148 postlingually deafened adults. Data were analyzed for bimodal summation using measures of speech perception in quiet and in noise...
March 19, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29525415/immune-mediated-inner-ear-disease-diagnostic-and-therapeutic-approaches
#16
José Ferreira Penêda, Nuno Barros Lima, Francisco Monteiro, Joana Vilela Silva, Rita Gama, Artur Condé
INTRODUCTION: Immune Mediated Inner Ear Disease (IMIED) is a rare form of sensorineural bilateral hearing loss, usually progressing in weeks to months and responsive to immunosuppressive treatment. Despite recent advances, there is no consensus on diagnosis and optimal treatment. METHODS: A review of articles on IMIED from the last 10 years was conducted using PubMed® database. RESULTS: IMIED is a rare disease, mostly affecting middle aged women...
March 7, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29500435/on-the-design-of-a-mems-piezoelectric-accelerometer-coupled-to-the-middle-ear-as-an-implantable-sensor-for-hearing-devices
#17
A L Gesing, F D P Alves, S Paul, J A Cordioli
The presence of external elements is a major limitation of current hearing aids and cochlear implants, as they lead to discomfort and inconvenience. Totally implantable hearing devices have been proposed as a solution to mitigate these constraints, which has led to challenges in designing implantable sensors. This work presents a feasibility analysis of a MEMS piezoelectric accelerometer coupled to the ossicular chain as an alternative sensor. The main requirements of the sensor include small size, low internal noise, low power consumption, and large bandwidth...
March 2, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29481695/factors-associated-with-benefit-of-active-middle-ear-implants-compared-to-conventional-hearing-aids
#18
Theodore R McRackan, William B Clinkscales, Jayne B Ahlstrom, Shaun A Nguyen, Judy R Dubno
OBJECTIVE: Identify factors associated with benefit of middle ear implants (MEIs) as compared to conventional hearing aids (HAs). STUDY DESIGN: Independent review of audiological data from a multicenter prospective U.S. Food and Drug Administration (FDA) clinical trial. Preoperative and postoperative earphone, unaided/aided/implanted pure-tone thresholds, and word recognition scores were evaluated. RESULTS: Ninety-one subjects were included in this study...
February 26, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29455623/rare-case-of-bilateral-aural-atresia-and-cochlear-dysplasia-when-cochlear-implantation-is-not-the-answer
#19
Maja Svrakic
OBJECTIVE AND IMPORTANCE: Reports of patients with concurrent middle and inner ear anomalies are rare. These patients present a surgical challenge for cochlear implantation. The surgical risk must be weighed against the predicted benefit of the patient's hearing outcome and subsequent development of speech and language as well as their quality of life. CLINICAL PRESENTATION: Thirteen-year-old boy presented to the Otology clinic for auditory rehabilitation options...
February 17, 2018: Cochlear Implants International
https://www.readbyqxmd.com/read/29433516/a-technical-review-and-evaluation-of-implantable-sensors-for-hearing-devices
#20
REVIEW
Diego Calero, Stephan Paul, André Gesing, Fabio Alves, Júlio A Cordioli
Most commercially available cochlear implants and hearing aids use microphones as sensors for capturing the external sound field. These microphones are in general located in an external element, which is also responsible for processing the sound signal. However, the presence of the external element is the cause of several problems such as discomfort, impossibility of being used during physical activities and sleeping, and social stigma. These limitations have driven studies with the goal of developing totally implantable hearing devices, and the design of an implantable sensor has been one of the main challenges to be overcome...
February 13, 2018: Biomedical Engineering Online
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