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Anthony G Schache, Yi-Chung Lin, Kay M Crossley, Marcus G Pandy
PURPOSE: Knowledge of hip biomechanics during locomotion is necessary for designing optimal rehabilitation programs for hip-related conditions. The purpose of this study was to: (1) determine how lower-limb muscle contributions to hip joint contact forces (HCFs) differed between walking and running; and (2) compare both absolute and per-unit-distance (PUD) loads at the hip during walking and running. METHODS: Kinematic and ground reaction force data were captured from eight healthy participants during overground walking and running at various steady-state speeds (walking: 1...
June 21, 2018: Medicine and Science in Sports and Exercise
Jingyan Yang, Virginie Lafage, Renaud Lafage, Justin Smith, Eric O Klineberg, Christopher I Shaffrey, Gregory Mundis, Richard Hostin, Douglas Burton, Christopher P Ames, Shay Bess, Han Jo Kim, Frank Schwab
STUDY DESIGN: Retrospective review of prospective multicenter database. OBJECTIVE: To investigate the determinants of patient satisfaction with respect to changes in functional limitations two-year after spinal deformity surgery. SUMMARY OF BACKGROUND DATA: For operatively treated adult spine deformity (ASD), patient satisfaction has become an important component of evaluating quality of care. METHODS: 430 operative ASD patients with two-year follow-up were analyzed...
June 21, 2018: Spine
Dong Jiang, Mengmeng Hao, Fangyu Ding, Jingying Fu, Meng Li
Zika virus, which has been linked to severe congenital abnormalities, is exacerbating global public health problems with its rapid transnational expansion fueled by increased global travel and trade. Suitability mapping of the transmission risk of Zika virus is essential for drafting public health plans and disease control strategies, which are especially important in areas where medical resources are relatively scarce. Predicting the risk of Zika virus outbreak has been studied in recent years, but the published literature rarely includes multiple model comparisons or predictive uncertainty analysis...
June 19, 2018: Acta Tropica
Rusdi Rusli, Mazharul Haque, Mohammad Saifuzzaman, Mark King
OBJECTIVE: Traffic crashes along mountainous highways may lead to injuries and fatalities more often than highways on plain topography; however, research focusing on the injury outcome of such crashes is relatively scant. The objective of this study was to investigate the factors affecting the likelihood that traffic crashes along rural mountainous highways result in injuries. METHOD: This study proposes a combination of decision tree and logistic regression techniques to model crash severity (injury vs non-injury), as the combined approach allows the specification of nonlinearities and interactions in addition to main effects...
June 22, 2018: Traffic Injury Prevention
Mojgan Pourhassan, Frank Neumann
The generalized travelling salesperson problem is an important NP-hard combinatorial optimization problem for which meta-heuristics, such as local search and evolutionary algorithms, have been used very successfully. Two hierarchical approaches with different neighbourhood structures, namely a Cluster-Based approach and a Node-Based approach, have been proposed by Hu and Raidl (2008) for solving this problem. In this paper, local search algorithms and simple evolutionary algorithms based on these approaches are investigated from a theoretical perspective...
June 22, 2018: Evolutionary Computation
Evan M Graboyes, Mark A Ellis, Hong Li, John M Kaczmar, Anand K Sharma, Eric J Lentsch, Terry A Day, Chanita Hughes Halbert
BACKGROUND: Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains unknown. METHODS: The authors used the National Cancer Data base from 2004 through 2013 to identify patients with HNSCC undergoing definitive treatment...
June 22, 2018: Cancer
M Stefansson, H H Askling, L Rombo
Our study showed the immune response before and after a booster against diphtheria given within the 20-year interval recommended in Sweden or after a prolonged interval. Of 40 travellers, 10/13 in recommended interval group were immune before booster and 19/27 with a delayed interval. After booster, 13/13 versus 26/27 were protected. One booster was sufficient to achieve immunity regardless of the interval.
June 1, 2018: Journal of Travel Medicine
Sandeep S Bhangoo
No abstract text is available yet for this article.
June 21, 2018: Neurosurgery
Tej D Azad, Gerald A Grant
No abstract text is available yet for this article.
June 21, 2018: Neurosurgery
Rajani Singh
The subscapular, anterior circumflex, and posterior circumflex arteries arise from the third part of the axillary artery. During dissection of the right upper limb of the cadaver of a 70-year-old male, a common trunk was observed arising from the third part of the axillary artery which, after traveling for 0.5 cm, bifurcated into subscapular and posterior circumflex humeral arteries. The common trunk was crossed anteriorly by the radial nerve. The medial nerve was formed by medial and lateral roots on the medial side of the third part of the axillary artery, remaining medial to the brachial artery up to the cubital fossa and then following its usual course thereafter...
July 2017: Jornal Vascular Brasileiro
Y X Zhang, W Feng
OBJECTIVE: To explore the influencing factors of elderly outpatient visits and to provide evidence for poverty reduction in health in the poor rural areas. METHODS: Through stratified sampling, a total of 1 271 aged people in four poverty Qi/County of Ulanqabcity were surveyed, including Qahar Right Wing Front Banner, Qahar Right Wing Middle Banner, Qahar Right Wing Rear Banner and Liangcheng County. Their socioeconomic and demographic characteristics, daily consumption, EuroQol five dimensions questionnaire(EQ-5D) and visual analogue scale (VAS),social support, health service needs and utilization were collected through cross-sectional household questionnaires...
June 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
Miroslav P Ivanov, Rene Ladurner, Ina Poser, Rebecca Beveridge, Evelyn Rampler, Otto Hudecz, Maria Novatchkova, Jean-Karim Hériché, Gordana Wutz, Petra van der Lelij, Emanuel Kreidl, James Ra Hutchins, Heinz Axelsson-Ekker, Jan Ellenberg, Anthony A Hyman, Karl Mechtler, Jan-Michael Peters
Chromosome segregation depends on sister chromatid cohesion which is established by cohesin during DNA replication. Cohesive cohesin complexes become acetylated to prevent their precocious release by WAPL before cells have reached mitosis. To obtain insight into how DNA replication, cohesion establishment and cohesin acetylation are coordinated, we analysed the interaction partners of 55 human proteins implicated in these processes by mass spectrometry. This proteomic screen revealed that on chromatin the cohesin acetyltransferase ESCO2 associates with the MCM2-7 subcomplex of the replicative Cdc45-MCM-GINS helicase...
June 21, 2018: EMBO Journal
Francesc Lopez Segui, Carme Pratdepadua Bufill, Nuria Abdon Gimenez, Jordi Martinez Roldan, Francesc Garcia Cuyas
BACKGROUND: In Catalonia, the Fundació TIC Salut Social's mHealth Office created the AppSalut Site to showcase to mobile apps in the field of health and social services. Its primary objective was to encourage the public to look after their health. The catalogue allows primary health care doctors to prescribe certified, connected apps, which guarantees a safe and reliable environment for their use. The generated data can be consulted by health care professionals and included in the patient's clinical history...
June 21, 2018: JMIR MHealth and UHealth
Farshid Bostanmaneshrad, Sadegh Partani, Roohollah Noori, Hans-Peter Nachtnebel, Ronny Berndtsson, Jan Franklin Adamowski
To date, few studies have investigated the simultaneous effects of macro-scale parameters (MSPs) such as land use, population density, geology, and erosion layers on micro-scale water quality variables (MSWQVs). This research focused on an evaluation of the relationship between MSPs and MSWQVs in the Siminehrood River Basin, Iran. In addition, we investigated the importance of water particle travel time (hydrological distance) on this relationship. The MSWQVs included 13 physicochemical and biochemical parameters observed at 15 stations during three seasons...
October 15, 2018: Science of the Total Environment
Joel Aik, Anita E Heywood, Anthony T Newall, Lee-Ching Ng, Martyn D Kirk, Robin Turner
Climate change is expected to bring about global warming and an increase in the frequency of extreme weather events. This may consequently influence the transmission of food-borne diseases. The short term associations between climatic conditions and Salmonella infections are well documented in temperate climates but not in the tropics. We conducted an ecological time series analysis to estimate the short term associations between non-outbreak, non-travel associated reports of Salmonella infections and observed climatic conditions from 2005 to 2015 for Singapore...
October 15, 2018: Science of the Total Environment
Benjamin Hampel, Matthias Reinacher, Jan S Fehr
No abstract text is available yet for this article.
June 18, 2018: Travel Medicine and Infectious Disease
Jarne M van Hattem, Maris S Arcilla, Constance Schultsz, Martin C Bootsma, Nienke Verhaar, Sjoerd P Rebers, Abraham Goorhuis, Martin P Grobusch, John Penders, Menno D de Jong, Tom van Gool, Aldert Bart
INTRODUCTION: A lack of prospective and longitudinal data on pre- and post-travel carriage of Blastocystis spp. complicates interpretation of a positive test post-travel. Therefore we studied dynamics of Blastocystis carriage in a cohort of Dutch travellers. METHODS: From the prospective, multicentre COMBAT study among 2001 Dutch travellers, a subset of 491 travellers was selected based on travel destination to 7 subregions (70 or 71 travellers each). Faecal samples taken directly before and after travel were screened for Blastocystis with qPCR, followed, when positive, by sequence analysis to determine subtypes...
June 18, 2018: Travel Medicine and Infectious Disease
Omar Zakary, Mostafa Rachik, Ilias Elmouki
First, we devise in this paper, a multi-regions discrete-time model which describes the spatial-temporal spread of an epidemic which starts from one region and enters to regions which are connected with their neighbors by any kind of anthropological movement. We suppose homogeneous Susceptible-Infected-Removed (SIR) populations, and we consider in our simulations, a grid of colored cells, which represents the whole domain affected by the epidemic while each cell can represent a sub-domain or region. Second, in order to minimize the number of infected individuals in one region, we propose an optimal control approach based on a travel-blocking vicinity strategy which aims to control only one cell by restricting movements of infected people coming from all neighboring cells...
August 2017: Infectious Disease Modelling
Jamil Shah, Abul Shahidullah
Intestinal parasitic infections are a major public health issue across the world and particularly in rural and urban areas of tropical and subtropical countries. Those at increased risk include inhabitants of poor and disadvantaged regions, which are more likely to have inadequate environmental sanitation, insufficient water supply, greater contact rates with reservoirs of infection, limited health literacy, and socioeconomic disparities. Of the intestinal nematodes (roundworms) that parasitize the human gastrointestinal tract, Ascaris lumbricoides is the largest in terms of size...
May 2018: Case Reports in Gastroenterology
Aïda M Valevicius, Quinn A Boser, Ewen B Lavoie, Glyn S Murgatroyd, Patrick M Pilarski, Craig S Chapman, Albert H Vette, Jacqueline S Hebert
BACKGROUND: Dexterous hand function is crucial for completing activities of daily living (ADLs), which typically require precise hand-object interactions. Kinematic analyses of hand trajectory, hand velocity, and grip aperture provide valuable mechanistic insights into task performance, but there is a need for standardized tasks representative of ADLs that are amenable to motion capture and show consistent performance in non-disabled individuals. Our objective was to develop two standardized functional upper limb tasks and to quantitatively characterize the kinematics of normative hand movement...
2018: PloS One
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