keyword
MENU ▼
Read by QxMD icon Read
search

Raynaud

keyword
https://www.readbyqxmd.com/read/29052562/clinical-profile-and-significance-of-mucocutaneous-lesions-of-primary-sj%C3%A3-gren-s-syndrome-a-large-cross-sectional-study-with-874-patients
#1
Lei Xuan, Yi-Dong Zhang, Li Li, Yue-Ping Zeng, Hao-Ze Zhang, Jing Wang, Zhen-Hua Dong
BACKGROUND: Mucocutaneous lesions are common features of primary Sjögren's syndrome (pSS), but only a few studies have focused on them. To demonstrate the profile of mucocutaneous lesions of pSS and further explore their potential clinical significance, we performed a cross-sectional study on 874 patients. METHODS: Demographic data, clinical manifestations, and laboratory results of 874 pSS patients were collected. Patients were divided into two groups according to the presence of mucocutaneous lesions...
October 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29044769/human-papillomavirus-vaccination-of-adult-women-and-risk-of-autoimmune-and-neurological-diseases
#2
A Hviid, H Svanström, N M Scheller, O Grönlund, B Pasternak, L Arnheim-Dahlström
BACKGROUND: Since 2006, human papillomavirus (HPV) vaccines have been introduced in many countries worldwide. Whilst safety studies have been reassuring, focus has been on the primary target group, the young adolescent girls. However, it is also important to evaluate safety in adult women where background disease rates and safety issues could differ significantly. OBJECTIVE: We took advantage of the unique Danish and Swedish nationwide healthcare registers to conduct a cohort study comparing incidence rate ratios (RRs) of 45 preselected serious chronic diseases in quadrivalent HPV (qHPV)-vaccinated and qHPV-unvaccinated adult women 18-44 years of age...
October 18, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29044628/possible-pro-inflammatory-role-of-heparin-binding-epidermal-growth-factor-like-growth-factor-in-the-active-phase-of-systemic-sclerosis
#3
Megumi Hirabayashi, Yoshihide Asano, Takashi Yamashita, Shunsuke Miura, Kouki Nakamura, Takashi Taniguchi, Ryosuke Saigusa, Takehiro Takahashi, Yohei Ichimura, Takuya Miyagawa, Ayumi Yoshizaki, Tomomitsu Miyagaki, Makoto Sugaya, Shinichi Sato
Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is a member of the EGF family growth factors, which affects multiple aspects of the wound healing process such as epithelialization, wound contraction and angiogenesis. In our study, we measured the serum HB-EGF levels of 51 systemic sclerosis (SSc) patients, which showed a significant increase compared with those of 20 normal subjects. Further analysis revealed a positive correlation between the HB-EGF level and pulmonary ground-glass score but no correlation between the former and pulmonary fibrosis score...
October 17, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/29017842/the-frisbee-maneuver-a-novel-method-to-abort-acute-attacks-of-raynaud-s-phenomenon
#4
Paul Curtiss, Gabriela Cobos, Kristen Lo Sicco, Andrew Franks
No abstract text is available yet for this article.
October 7, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28993902/cardiac-involvement-in-undifferentiated-connective-tissue-disease-at-risk-for-systemic-sclerosis-otherwise-referred-to-as-very-early-early-systemic-sclerosis-a-tdi-study
#5
Michele D'Alto, Antonella Riccardi, Paola Argiento, Ilaria Di Stefano, Emanuele Romeo, Agostino Mattera Iacono, Antonello D'Andrea, Serena Fasano, Alessandro Sanduzzi, Marialuisa Bocchino, Ludovico Docimo, Salvatore Tolone, Maria Giovanna Russo, Gabriele Valentini
Undifferentiated connective tissue disease at risk for systemic sclerosis (UCTD-risk-SSc), otherwise referred to as very early-early SSc, is a condition characterized by Raynaud's phenomenon with serum SSc marker autoantibodies and/or typical capillaroscopic findings and unsatisfying classification criteria for the disease. The aim of the present study was to assess the prevalence of right (RV) or left ventricular (LV) systolic and/or diastolic dysfunction by standard echocardiography and tissue Doppler imaging (TDI)...
October 9, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/28992170/points-to-consider-raynaud-s-phenomenon-in-systemic-sclerosis
#6
REVIEW
Maurizio Cutolo, Vanessa Smith, Daniel E Furst, Dinesh Khanna, Ariane L Herrick
RP is an exaggerated vasospastic response to cold or emotion. Randomized, double-blind, placebo-controlled trials with either parallel group or cross-over trials should be mainly considered. Cross-over design, which is good for early phase trials of immediate or very short-term outcomes, is important in a condition as heterogeneous as RP: a wash-out period between treatment arms should always be included to minimize the possibility of a period (carry-over) effect. Duration of RP trials is usually constrained by the need to complete these over a single season, usually winter when the weather is colder...
September 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28985172/treating-raynaud-phenomenon-beyond-staying-warm
#7
REVIEW
Samantha C Shapiro, Fredrick M Wigley
Raynaud phenomenon is an overactive vascular response to cold and emotional stress that results in cutaneous color changes and sensory symptoms in the digits. It can be idiopathic (primary) or secondary to another condition; the latter can be more severe and more apt to lead to ischemic complications such as digital ulceration and even loss of digits. If nonpharmacologic interventions prove inadequate, then vasodilator agents are used.
October 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28981361/follow-up-of-treatment-response-with-dynamic-doppler-ultrasound-in-raynaud-phenomenon
#8
Ugur Toprak, Zeynep Ozbalkan, Murat Erdugan, Selcuk Parlak, Sevinc Can Sandıkcı, Tunca Kaya, Suzan Şaylısoy
OBJECTIVE: The purpose of this study was to investigate the role of flow parameters obtained with dynamic Doppler ultrasound in the objective follow-up of treatment response in patients with Raynaud phenomenon (RP). SUBJECTS AND METHODS: The study included 33 patients with newly diagnosed primary RP, 31 with secondary RP, and 26 healthy participants (control subjects). Both groups of patients with RP underwent sonography before and after treatment. The control group underwent sonography once...
October 5, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28980901/long-term-treatment-of-scleroderma-related-digital-ulcers-with-iloprost-a-cohort-study
#9
Michele Colaci, Federica Lumetti, Dilia Giuggioli, Serena Guiducci, Silvia Bellando-Randone, Ginevra Fiori, Marco Matucci-Cerinic, Clodoveo Ferri
OBJECTIVES: Raynaud's phenomenon and chronic/recurrent digital ulcers (DU) are main features of systemic sclerosis (SSc). Their treatment includes both systemic (i.e., iloprost) and local therapies. We report the therapeutic effects of iloprost in a cohort of SSc patients during a long-lasting follow-up period. METHODS: Fifty consecutive SSc patients (M/F 7/43, age at SSc diagnosis 43.5±12.7SD years) received iloprost infusions for 10±4.2SD years. Iloprost schedule consisted in monthly infusion at 0...
September 18, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28975961/outcomes-rates-and-predictors-of-transition-of-isolated-raynaud-s-phenomenon-a-systematic-review-and-meta-analysis
#10
Francesca Ingegnoli, Nicola Ughi, Chiara Crotti, Marta Mosca, Chiara Tani
QUESTIONS: Published studies lack clear indicators of risk and predictors of transition from Raynaud's phenomenon (Rp) to connective tissue diseases (CTDs). Therefore, we aimed to study the outcomes, rates and predictors of transition to CTDs in patients with Rp. METHODS: A sensitive search was developed in Medline and Embase. Observational studies reporting incidence and risk factors of transition from Rp to a CTD were analysed by two independent reviewers. The main outcome was the rate of transition to a CTD; the secondary outcome was the evaluation of predictors...
October 4, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28967806/pulmonary-pathologic-manifestations-of-anti-alanyl-trna-synthetase-anti-pl-12-related-inflammatory-myopathy
#11
Frank Schneider, Samuel A Yousem, Chester V Oddis, Rohit Aggarwal
CONTEXT: - Patients with anti-aminoacyl-tRNA synthetase syndrome (ARS), a subset of idiopathic inflammatory myopathy, have a high prevalence of lung involvement. Autoantibodies directed against alanyl-tRNA synthetase (anti-PL-12 Abs) represent 1 of the 8 autoantibodies currently described under the rubric of ARS. OBJECTIVE: - To describe the clinical, radiographic, and pulmonary histopathologic findings in patients possessing anti-PL-12 autoantibodies. DESIGN: - Patients with anti-PL-12 ARS were identified in the University of Pittsburgh Idiopathic Inflammatory Myopathy registry...
October 2, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28966213/elevated-serum-anti-gm-csf-antibodies-before-the-onset-of-autoimmune-pulmonary-alveolar-proteinosis-in-a-patient-with-sarcoidosis-and-systemic-sclerosis
#12
Mari Yamasue, Shin-Ichi Nureki, Yuko Usagawa, Tomoko Ono, Hiroyuki Matsumoto, Takamasa Kan, Jun-Ichi Kadota
Pulmonary alveolar proteinosis (PAP) is characterized by the accumulation of periodic acid-schiff stain-positive lipoproteinaceous materials in the alveolar space due to impaired surfactant clearance by alveolar macrophage. Autoimmune PAP is the most common form of PAP, but rarely accompanies collagen disease or sarcoidosis. We report here a rare case of autoimmune PAP preceded by systemic sclerosis and sarcoidosis. A 64-year-old woman was admitted to our hospital for blurred vision, muscle weakness of extremities, Raynaud's phenomenon, and exertional dyspnea...
2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28960445/vascular-branches-from-cutaneous-nerve-of-the-forearm-and-hand-application-to-better-understanding-raynaud-s-disease
#13
K Umemoto, M Ohmichi, Y Ohmichi, T Yakura, N Hammer, D Mizuno, M Naito, T Nakano
INTRODUCTION: Cutaneous nerves have branches called vascular branches (VBs) that reach arteries. VBs are thought to be involved in arterial constriction, and this is the rationale for periarterial sympathectomy as a treatment option for Raynaud's disease. However, the branching patterns and distribution areas of the VBs remain largely unclear. The aim of the present study was to investigate the anatomical structures of the VBs of the cutaneous nerves. MATERIALS AND METHODS: Forty hands and forearms were examined to assess the branching patterns and distribution areas of the VBs of the superficial branch of the radial nerve (SBRN), the lateral antebrachial cutaneous nerve (LACN), the medial antebrachial cutaneous nerve (MACN), and the palmar cutaneous branch of the ulnar nerve (PCUN)...
September 29, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28957564/reproducibility-of-the-scleroderma-pattern-assessed-by-wide-field-capillaroscopy-in-subjects-suffering-from-raynaud-s-phenomenon
#14
MULTICENTER STUDY
Carine Boulon, Sophie Blaise, Isabelle Lazareth, Claire Le Hello, Marc-Antoine Pistorius, Bernard Imbert, Marion Mangin, Pierre Sintes, Patricia Senet, Joëlle Decamps-Le Chevoir, Laurent Tribout, Patrick Carpentier, Joël Constans
Objectives: The aim of this work was to study inter- and intra-observer agreement for the diagnosis of scleroderma pattern by wide-field capillaroscopy. Methods: Images were taken from 50 patients known to have SSc and 50 controls consulting for RP who did not have SSc. These images were rated simultaneously by 11 experienced vascular medicine physicians as scleroderma pattern or not. Two weeks later, 7 of the 11 observers again rated the same images. Results: Inter-observer agreement was almost perfect between the 11 observers (κ 0...
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28954092/anti-neutrophil-cytoplasmic-antibodies-in-new-onset-systemic-lupus-erythematosus
#15
Fang Su, Weiguo Xiao, Pingting Yang, Qingyan Chen, Xiaojie Sun, Tienan Li
Background: The clinical significance of anti-neutrophil cytoplasmic antibodies in patients with new-onset systemic lupus erythematosus, especially in systemic disease accompanied by interstitial lung disease remains to be elucidated. Objectives: This study was designed to investigate the role of anti-neutrophil cytoplasmic antibodies in new-onset systemic lupus erythematosus patients. Methods: A hundred and seven patients with new-onset SLE were enrolled...
July 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28953168/bipedicle-flaps-for-posterior-elbow-reconstruction
#16
Kyle J Chepla, Shirley Shue, Bram R Kafuman
Chronic posterior elbow soft tissue defects often require soft tissue reconstruction because of exposure of the underlying triceps tendon and proximal ulna. Current options for soft tissue coverage require sacrifice of a local muscle or microsurgery. The purpose of this study is to evaluate patient and surgical outcomes after reconstruction of small-sized to medium-sized (<50 cm) posterior elbow defects with bipedicle advancement flaps. A retrospective chart review was performed for 3 patients who underwent posterior elbow reconstruction with bipedicle flaps...
September 25, 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/28940121/anti-cenp-b-and-anti-topo-1-containing-sera-from-systemic-sclerosis-related-diseases-with-raynaud-s-phenomenon-induce-vascular-endothelial-cell-senescence-not-via-classical-p53-p21-pathway
#17
Chieh-Yu Shen, Ko-Jen Li, Pei-Hsuan Lai, Chia-Li Yu, Song-Chou Hsieh
Raynaud's phenomenon (RP) is the earliest and most common clinical manifestation in patients with systemic sclerosis (SSc) and its related diseases containing anti-TOPO-1 and/or anti-CENP-B autoantibodies in the sera. However, the cause-effect relationship between the two autoantibodies and RP remains elucidation. Sera containing anti-CENP-B and anti-TOPO-1 autoantibodies were obtained from SSc-related diseases manifesting RP. The polyclonal auto-antibodies were purified from pooled sera by affinity chromatography...
September 23, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28937580/diagnosis-of-systemic-inflammatory-diseases-among-patients-admitted-for-acute-pericarditis-with-pericardial-effusion
#18
Maureen Assayag, Rachid Abbas, Noémie Chanson, Anne Perozziello, Gregory Ducrocq, Jean-François Alexandra, Antoine Dossier, Thomas Papo, Karim Sacre
AIMS: Acute pericarditis may be the heralding manifestation of various systemic inflammatory diseases (SIDs). The aim of this study was to identify clinical indicators for SIDs in patients admitted for acute pericarditis with pericardial effusion. METHODS: All consecutive adult patients hospitalized in a Department of Internal Medicine over a 10-year period for acute pericarditis with pericardial effusion were retrospectively reviewed. Patients with cancer and tuberculosis were excluded...
September 20, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28930245/antioxidant-and-antimicrobial-activities-of-the-essential-oil-of-achillea-millefolium-l-grown-in-france
#19
Chaker El-Kalamouni, Petras Rimantas Venskutonis, Bachar Zebib, Othmane Merah, Christine Raynaud, Thierry Talou
Background: This study aimed to examine the composition of essential oil (EO) of A. millefolium aerial parts wild plant grown in France and evaluate its antioxidant, antibacterial, and antifungal activities. Methods: GC-MS was used to identify the chemical composition of EO. Antioxidant activity (AA) of EO was evaluated by Oxipres method. Antimicrobial activity of EO was evaluated by Agar-well diffusion and a broth microdilution assay. Results: Forty-three volatile compounds were identified. Major compounds were camphor (12...
May 19, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28920529/surgical-interventions-for-organ-and-limb-ischemia-associated-with-primary-and-secondary-antiphospholipid-antibody-syndrome-with-arterial-involvement
#20
Carlos A Hinojosa, Javier E Anaya-Ayala, Karla Bermudez-Serrato, Ramón García-Alva, Hugo Laparra-Escareno, Adriana Torres-Machorro, Rene Lizola
OBJECTIVE: The association of antiphospholipid antibody syndrome (APS) and hypercoagulability is well known. Arterial compromise leading to ischemia of organs and/or limbs in patients with APS is uncommon, frequently unrecognized, and rarely described. We evaluated our institutional experience. METHODS: Retrospective review was conducted. From August 2007 to September 2016, 807 patients with diagnosis of APS were managed in our Institution. Patients with primary and secondary APS who required interventions were examined...
November 2017: Vascular and Endovascular Surgery
keyword
keyword
467
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"