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Topical ivermectin

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https://www.readbyqxmd.com/read/28749307/recurrent-ear-mite-otodectes-cynotis-infestation-in-three-related-groups-of-patagonian-cavies-dolichotis-patagonum
#1
Carolina Lopes da Cruz, Torres Alpino, Jack Kottwitz
:  Two of three groups of Patagonian cavies ( Dolichotis patagonum ) contracted Otodectes cynotis infestations after exposure to mite-infested feral cats. Otodectes cynotis infestations were initially identified in 9 of 10 cavies in group 1. Multiple feral cats with O. cynotis infestations were observed in the vicinity of the Patagonian cavies and were subsequently removed. The Patagonian cavies were initially treated with ivermectin (0.4 mg/kg s.q.) every 2 wk, but ivermectin was discontinued after the third treatment due to injury to one of the Patagonian cavies during capture...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28749021/prophylactic-and-therapeutic-efficacy-of-australian-registered-insecticide-formulations-against-old-world-screwworm-chrysomya-bezziana-infestation
#2
P J James, A H Wardhana, G W Brown, D G Mayer, R Urech
OBJECTIVE: To determine the prophylactic and therapeutic efficacy of Australian-registered insecticide formulations against Old World screwworm (OWS) myiases for potential use in screwworm containment and eradication programs. METHODS: The longevity of protection provided by six insecticidal formulations (subcutaneous ivermectin, doramectin and abamectin, a topically applied aqueous formulation of spinosad, ivermectin controlled-release capsule and a dicyclanil spray-on formulation) was tested using implants of 1st-instar OWS larvae on Javanese thin-tail sheep...
August 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28728857/-rosacea-new-data-for-better-care
#3
B Cribier
In the last 10 years, numerous studies have been published that throw new light on rosacea, in all areas of the disease. This overview summarises all the key developments, based on the indexed bibliography appearing in Medline between 2007 and 2017. Recent epidemiological data show that the prevalence of the disease is doubtless greater than estimated hitherto (more than 10% of adults in some countries) and that we should not overlook rosacea in subjects with skin phototypes V or VI, a condition that exists on all continents...
July 17, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28653460/dual-anti-inflammatory-and-antiparasitic-action-of-topical-ivermectin-1-in-papulopustular-rosacea
#4
M Schaller, L Gonser, K Belge, C Braunsdorf, R Nordin, A Scheu, C Borelli
BACKGROUND: Recently, therapy of rosacea with inflammatory lesions (papulopustular) has improved substantially with the approval of topical ivermectin 1% cream. It is assumed to have a dual mode of action with anti-inflammatory capacities and anti-parasitic effect against Demodex, which however has not yet been demonstrated in vivo. AIM: To find scientific rationale for the dual anti-inflammatory and anti-parasitic mode of action of topical ivermectin 1% cream in patients with rosacea...
June 27, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28639722/european-guideline-for-the-management-of-scabies
#5
C M Salavastru, O Chosidow, M J Boffa, M Janier, G S Tiplica
Scabies is caused by Sarcoptes scabiei var. hominis. The disease can be sexually transmitted. Patients' main complaint is nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts and may be associated with reduced or absent pruritus. Recommended treatments are permethrin 5% cream, oral ivermectin and benzyl benzoate 25% lotion. Alternative treatments are malathion 0.5% aqueous lotion, ivermectin 1% lotion and sulphur 6-33% cream, ointment or lotion...
June 22, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28561292/guideline-for-the-diagnosis-and-treatment-of-scabies-in-japan-third-edition-executive-committee-of-guideline-for-the-diagnosis-and-treatment-of-scabies
#6
(no author information available yet)
In the current work, we present our new guideline for the diagnosis and treatment of scabies which we, the Executive Committee convened by the Japanese Dermatological Association, developed to ensure proper diagnosis and treatment of scabies in Japan. Approval of phenothrin topical use under the National Health Insurance in August 2014 led to this action. Permethrin, a topical anti-scabietic medication belonging to the same pyrethroid group as phenothrin, is already in use worldwide. In this guideline, we introduce criteria for a proper diagnosis of scabies, treatment algorithm for common and crusted (hyperkeratotic) scabies, and prevention...
May 31, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28472570/scabies-a-clinical-update
#7
Myra Hardy, Daniel Engelman, Andrew Steer
BACKGROUND: Scabies is a common, yet neglected, skin disease. Scabies occurs across Australia, but most frequently in socioeconomically disadvantaged populations in tropical regions, including in remote Aboriginal and Torres Strait Islander communities. In temperate settings, the disease clusters in institutional care facilities. OBJECTIVE: The objective of this article is to provide updates on the clinical diagnosis and treatment approaches for scabies in Australia...
2017: Australian Family Physician
https://www.readbyqxmd.com/read/28408046/-evaluation-of-practices-in-the-management-of-scabies-in-children
#8
M-S Lê, M-A Richard, K Baumstarck, S Hesse, C Gaudy-Marqueste, J-J Grob, S Mallet
BACKGROUND: Scabies has been on the rise in France in recent years and has posed therapeutic problems, mainly due to the withdrawal of benzyl benzoate. The objective of this study was to describe prescribing practices for scabies in children. METHODS: A national survey was conducted by means of a standardized questionnaire covering various clinical situations of scabies and the drugs used preferentially according to age, which was sent out between December 2014 and March 2015 to members of the clinical research group of the French Society of Paediatric Dermatology...
April 10, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28385424/treatment-of-human-scabies-with-oral-ivermectin-eczematous-eruptions-as-a-new-non-reported-adverse-event
#9
J Sanz-Navarro, C Feal, E Dauden
BACKGROUND: Oral ivermectin is an alternative therapy for human scabies infection due to its ease of administration and good safety profile. However, there is no definitive consensus on the optimal dosing regimen. OBJECTIVE: To describe the treatment of human scabies with different dosages of oral ivermectin and the possible adverse events. METHODS: 23 patients with human scabies were treated with oral ivermectin: 10 patients received a single oral dose of 200μg/kg and 13 a dose of 400μg/kg...
April 3, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28384914/orbital-myiasis-with-scalp-pediculosis-and-buccal-abscess-an-uncommon-presentation
#10
Nidhi Kaeley, Rajeev Mohan Kaushik, Richa Rajput, Renu Dhasmana, Anurag Bhargava
We present a case of severe orbital myiasis caused by Osteris ovis, also known as sheep nasal botfly which is an uncommon manifestation of maggot infestation. Our patient was successfully treated with oral as well as topical ivermectin. The experience of ivermectin as an anti-parasitic agent in the treatment of orbital myiasis, although a known entity, is still limited among medical professionals including ophthalmologists. Thus, we would like to highlight the role of oral ivermectin as an anti-parasitic agent in the treatment of orbital myiasis facilitating the removal of maggots; thus, precluding the need for exploratory surgery...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28329606/clinical-applications-of-topical-ivermectin-in-dermatology
#11
Omid Zargari, Nessa Aghazadeh, Fatemeh Moeineddin
Ivermectin (IVM) is a broad-spectrum anti-parasitic drug with significant anti-inflammatory properties. The emergence of treatment resistance to lindane, permethrin, and possibly malathion complicates the global strategy for management of common parasitic skin diseases such as scabies and head lice. In this regard. IVM has been safely and effectively used in the treatment of these common human infestations. In addition, IVM may be useful in inflammatory cutaneous disorders such as papulopustular rosacea where demodex may play a role in pathogenesis...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28326184/unilateral-demodicidosis-of-face-mimicking-hansens-disease
#12
Deepak Vashisht, Jatinder Singh, Sukriti Baveja, Rohit Tiwari, Anuj Bhatnagar
Demodicosis is a common parasitic infection of the hair follicles and the pilosebaceous unit by the Demodex mites viz. Demodex folliculorum and Demodex brevis. Infection by this parasite is common among immunocompromised and elderly. We report a case of facial Demodicosis which presented like atypical rosacea with a gradually progressing swelling and redness on right side of face which was initially diagnosed as a case of Hansen's disease. Skin biopsy revealed follicular dilatation with presence of Demodex mite along with intense perifollicular lymphomononuclear infiltrate...
June 15, 2016: Dermatology Reports
https://www.readbyqxmd.com/read/28243927/topical-treatment-of-rosacea-with-ivermectin-inhibits-gene-expression-of-cathelicidin-innate-immune-mediators-ll-37-and-klk5-in-reconstructed-and-ex-vivo-skin-models
#13
Séverine Thibaut de Ménonville, Carine Rosignoli, Estelle Soares, Manon Roquet, Béatrice Bertino, Jean-Paul Chappuis, Claire Defoin-Platel/Chaussade, David Piwnica
INTRODUCTION: Numerous intrinsic and extrinsic factors have been associated with the pathophysiology of rosacea, including dysregulation of innate immunity. A high level of cathelicidin antimicrobial peptides (e.g., LL-37) has been shown in the facial skin of patients with rosacea. Excessive production of both LL-37 and KLK5, the serine protease responsible for its cleavage, has been suggested to play a role in the pathophysiology of rosacea. Ivermectin 10 mg/g cream, indicated for the treatment of inflammatory lesions of rosacea, is reported to have dual anti-parasitic and anti-inflammatory properties...
June 2017: Dermatology and Therapy
https://www.readbyqxmd.com/read/28078983/cutaneous-larva-migrans
#14
Alexander K C Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Cutaneous larva migrans is one of the most common skin diseases reported in travelers returning from tropical regions. Western physicians, however, are often not familiar of this condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications, and treatment of cutaneous larva migrans. METHODS: A PubMed search was completed in Clinical Queries using the key term "cutaneous larva migrans"...
January 10, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28063594/-scabies-of-the-nail-unit-in-an-infant
#15
A Finon, G Desoubeaux, M Nadal, G Georgescou, R Baran, A Maruani
BACKGROUND: There are no guidelines regarding the management of scabies in infants and recurrence is common at this age. We report the case of an infant with subungual hyperkeratosis and ungual lesions subsequent to classic scabies. PATIENTS AND METHODS: A 7-month-girl, treated 6 weeks earlier with esdepallethrin for scabies, consulted for acquired lesions on 3 toe nails. These nails were thickened and displayed subungual hyperkeratosis. Physical examination of the skin, the finger nails and mucous membranes was otherwise normal...
May 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28062820/epidemiology-diagnosis-and-treatment-of-scabies-in-a-dermatology-office
#16
Kathryn L Anderson, Lindsay C Strowd
BACKGROUND: Scabies is a neglected skin disease, and little is known about current incidence and treatment patterns in the United States. The purpose of this study was to examine demographic data, treatment types, success of treatment, and misdiagnosis rate of scabies in an outpatient dermatology clinic. METHODS: A retrospective chart review of patients diagnosed with scabies within the past 5 years was performed. RESULTS: A total of 459 charts were identified, with 428 meeting inclusion criteria...
January 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28052336/topical-ivermectin-improves-allergic-skin-inflammation
#17
E Ventre, A Rozières, V Lenief, F Albert, P Rossio, L Laoubi, D Dombrowicz, B Staels, L Ulmann, V Julia, E Vial, A Jomard, F Hacini-Rachinel, J-F Nicolas, M Vocanson
BACKGROUND: Ivermectin (IVM) is widely used in both human and veterinary medicine to treat parasitic infections. Recent reports have suggested that IVM could also have anti-inflammatory properties. METHODS: Here, we investigated the activity of IVM in a murine model of atopic dermatitis (AD) induced by repeated exposure to the allergen Dermatophagoides farinae, and in standard cellular immunological assays. RESULTS: Our results show that topical IVM improved allergic skin inflammation by reducing the priming and activation of allergen-specific T cells, as well as the production of inflammatory cytokines...
January 4, 2017: Allergy
https://www.readbyqxmd.com/read/27998311/disseminated-tungiasis-in-a-78-year-old-woman-from-tanzania-a-case-report
#18
Pedro Pallangyo, Paulina Nicholaus
BACKGROUND: Tungiasis is one of the neglected tropical diseases; it affects up to 40% of individuals living in societies with poor housing and sanitation standards. In endemic areas, Tunga infestation, which predominantly affects the periungual areas of the lower limbs in humans, is associated with considerable morbidity and poor quality of life. CASE PRESENTATION: A 78-year-old woman of African descent presented with pain, inflammation, suppuration, ulceration, and deformation of digits of all four limbs...
December 20, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27988991/egfri-induced-papulopustular-rosacea-like-rash-successfully-treated-with-topical-ivermectin
#19
LETTER
S Käser, C Ruini, M Ezmerli, T von Braunmühl, D Hartmann, T Ruzicka, M Reinholz
No abstract text is available yet for this article.
December 18, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27976437/monitoring-structural-changes-in-demodex-mites-under-topical-ivermectin-in-rosacea-by-means-of-reflectance-confocal-microscopy-a-case-series
#20
LETTER
C Ruini, E Sattler, D Hartmann, M Reinholz, T Ruzicka, T von Braunmühl
No abstract text is available yet for this article.
December 15, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
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