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Sarah Lohrenz, Jessica Minion, Mamata Pandey, Kumudhini Karunakaran
In the literature, cases of blastomycosis in Canada have been documented in provinces bordering the Great Lakes, including Ontario and Quebec, as well as Manitoba. This is the first study to our knowledge reporting cases of mycosis seen in southern Saskatchewan suggesting a broader area of endemicity. We searched the Regina Qu'Appelle Health Region (RQHR) Microbiology Laboratory for all culture-confirmed cases of Blastomyces from January 2000 to December 2015 and identified 15 cases. Thirteen cases were reviewed, identifying common presenting symptoms, misdiagnosis, comorbidities, travel history, time from presentation to diagnosis, diagnostic specimen, treatment, and clinical outcome...
June 19, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
Wei Li, Tong Xin, Yuxin Hu, Peng Gao, Mo Chen, Jie Zhang
RATIONALE: Pulmonary hemangioma is a rare thoracic condition that can lead to hemoptysis. Here we report a case that presented with lumen dilatation suggestive of bronchiectasis on high-resolution computed tomography (CT) and was misdiagnosed as bronchiectasis for more than 10 years. PATIENT CONCERNS: A 41-year-old female patient was admitted to the Department of Respiratory Medicine due to hemoptysis. DIAGNOSES: The patient was misdiagnosed as having bronchiectasis for more than 10 years...
June 2018: Medicine (Baltimore)
Lixia Sun, Yaru Dong, Xin Wang, Baihui Shan, Min Zhang
RATIONALE: Sporotrichosis is the most common subcutaneous mycosis. It is caused by the dimorphic fungus Sporothrix schenckii. Ocular sporotrichosis is uncommon and has been rarely reported. PATIENT CONCERNS: We describe a 34-year-old female who presented with a nodule increasing in size near the medial angle of the left eye. Originally, she was misdiagnosed with a dacryocyst space-occupying lesion, and the lesion was removed by surgery. DIAGNOSES: Findings of fungal structures in the histopathological examination contributed to the diagnosis of Sporothrix dacryocystitis...
June 2018: Medicine (Baltimore)
W-H Lei, Wen-Feng Wu, Jin-Yang Zhen, Yang-Hui Li, Jie Li, Jun Xin
RATIONALE: Most patients with paratesticular rhabdomyosarcoma may typically present as a unilateral, painless palpable scrotum mass. However, only a few cases of RMS presenting as painful edema of the scrotum mimicing epididymitis. We herein report an unusual case of alveolar paratesticular rhabdomyosarcoma misdiagnosed as epididymitis. PATIENT CONCERNS: A 19-year-old adolescent, presented to urologist with painful swelling of the scrotum on the left side over the preceding several days...
June 2018: Medicine (Baltimore)
Liyan Lu, Fengfang Li, Yamei Zhang, Peng Wang, Xindao Yin, Wenbin Li
RATIONALE: Small cell lung cancer accounts for 15-20% of all lung cancers and is the most common pulmonary neuroendocrine neoplasm. Most small cell lung cancers arise from lobar or main bronchi, the most common manifestations of small cell lung cancer is a large mass centrally located within the lung parenchyma or a mediastinal mass involving the hilus. Small cell lung cancer is easily ignored by clinicians without lung parenchyma and hilus involvement. Here, we report a case of small cell lung cancer, which was misdiagnosed as the lymphoma in contrast enhanced CT and Ga-DOTA-NOC PET/CT imagings...
June 2018: Medicine (Baltimore)
Yilun Wang, Min Zhu, Yunqi Bao, Li Li, Liping Zhu, Feng Li, Jinhua Xu, Jun Liang
RATIONALE: Cutaneous mucormycosis is an uncommon disease and occurs rarely in immunocompetent patients. PATIENT CONCERNS: We reported the case of a 37-year-old man presenting with a skin lesion on the left side of the chest wall with no history of trauma or primary diseases. He was firstly misdiagnosed as tuberculosis and the proper treatment was thus delayed. DIAGNOSES: Histopathological examination and fungal culture of the lesion confirmed cutaneous mucormycosis...
June 2018: Medicine (Baltimore)
Jianbing Ma, Weiqiang Zhang, Yijuan Huang, Lizhang Wang, Jia Wang, Linna Yuan, Jingfeng Zhang
RATIONALE: Primary pulmonary angiosarcoma is a rare disease. Here, we report the case of primary pulmonary angiosarcoma diagnosed computed tomographic pulmonary angiography (CTPA) and discuss its specific imaging characteristics. PATIENT CONCERNS: A 46-year-old man was admitted for cough and shortness of breath. Thoracic CTPA images demonstrated a high-attenuation lesion surrounding by a halo sign in upper lobe of right lung, and the dilated vessel was also seen in lower lobe of right lung...
June 2018: Medicine (Baltimore)
Z W Zhang, Z Y Zheng, R Li, S Y Zhou, W Tang, J P Zhou, B Wang
OBJECTIVES: To analyse 73 medical malpractice cases of pediatrics for discussing the importance of forensic pathology in solving the issues such as medical malpractice of pediatrics. METHODS: From January 2002 to August 2016, 73 medical malpractice cases of pediatrics with age of death between 28 days old and 10 years old were collected from Institute of Judical Expertise of Nanjing Medical University. The relationship between causes of death and related medical institutions was retrospectively analysed...
April 2018: Fa Yi Xue za Zhi
Kristina Crothers, Carla V Rodriguez, Robin M Nance, Kathleen Akgun, Shahida Shahrir, Joon Kim, Guy W Soo Hoo, Amir Sharafkhaneh, Heidi M Crane, Amy C Justice
PURPOSE: No prior studies have addressed the performance of electronic health record (EHR) data to diagnose chronic obstructive pulmonary disease (COPD) in people living with HIV (PLWH), in whom COPD could be more likely to be underdiagnosed or misdiagnosed, given the higher frequency of respiratory symptoms and smoking compared with HIV-uninfected (uninfected) persons. METHODS: We determined whether EHR data could improve accuracy of ICD-9 codes to define COPD when compared with spirometry in PLWH vs uninfected, and quantified level of discrimination using the area under the receiver-operating curve (AUC)...
June 20, 2018: Pharmacoepidemiology and Drug Safety
Youting Bao, Zhichao Liu, Meiying Guo, Butuo Li, Xindong Sun, Linlin Wang
Extramedullary hematopoiesis (EMH) usually occurs in hematological disease, but more rarely develops in cases of malignant solid tumors. Due to its features on computed tomography (CT) and magnetic resonance imaging (MRI) that are atypical, EMH in tumor patients might easily be misdiagnosed as metastasis leading to the improper TNM staging and inappropriate therapy. Here, we reported the first case of pleural EMH occurring in a patient with esophageal carcinoma whose pleural lesion was first diagnosed as metastasis and confirmed EMH after the needle biopsy...
2018: Cancer Management and Research
Mei Liang, Jialin Jiang, Hongmei Dai, Xiafei Hong, Xianlin Han, Lin Cong, Anli Tong, Fang Li, Yaping Luo, Weinan Liu, Liangrui Zhou, Wenyu Di, Wenming Wu, Yupei Zhao
BACKGROUND: A patient with a rare pediatric insulinoma and MEN1 syndrome was treated by robotic enucleation surgery. CASE PRESENTATION: We present a case of a 9-year-old girl presenting with repeated loss of consciousness, concomitant with a pale face, palpitations, and convulsions, which had persisted for 2 years and had been aggravated during the previous 2 months. She was previously misdiagnosed with epilepsy in another hospital. We further examined her while she was hospitalized...
June 19, 2018: BMC Surgery
J M Fan, S X Wen, B Q Wang, R Han, Y Y Yang, Q Q Zhu
The clinical manifestations were pharyngalgia anddysphagia. Physical examination found that the size of a mobilizable and hard lymph node in the area of the right neck Ⅱ was about 2.0 cm×2.0 cm. Ultrasound examination demonstrated abnormal lymphadenopathy in bilateral neck which was considered metastatic cancer. Neck CT showed occupation of the hypopharynx, thickening bilateral aryepiglottic folds and false vocal cords, and enlargement lymph node in the bilateral neck Ⅱ area. Upper gastrointestinal radiography: The mucosa from the lower border of right pear-shaped fossa to the entrance of the esophagus was disrupted, and the partial lumen was narrowed...
June 5, 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
A S Darrigade, C Léauté-Labrèze, F Boralevi, A Taïeb, B Milpied
BACKGROUND: Contact dermatitis from topical antiseptic use has been reported mostly in adults but rare cases of chlorhexidine contact dermatitis have also been described in young children. OBJECTIVE: To evaluate contact allergic dermatitis to antiseptics in young children. METHODS: The children mostly referred for a misdiagnose (cellulitis) were patch tested with a selection of the European baseline series, an antiseptics series and the personal topical products used...
June 19, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
T Furuta, S Baba, M Yamade, T Uotani, T Kagami, T Suzuki, S Tani, Y Hamaya, M Iwaizumi, S Osawa, K Sugimoto
BACKGROUND: Although autoimmune gastritis (AIG) is generally considered relatively rare, we frequently encounter AIG among patients at to our hospital who have experienced at least two episodes of Helicobacter pylori eradication failure. AIMS: We investigated the incidence of AIG in consecutive patients who consulted our department for H. pylori eradication with reference to eradication history. METHODS: A total of 404 consecutive patients who visited the H...
June 19, 2018: Alimentary Pharmacology & Therapeutics
Samuel Clifton Willimon, Michael T Busch, Crystal A Perkins
BACKGROUND: Pigmented villonodular synovitis (PVNS) is a benign proliferative synovial disorder most commonly described in adults. The purpose of this study is to describe the presentation and management of a large single-center series of pediatric patients with PVNS of the knee. METHODS: A retrospective review was performed of consecutive pediatric patients treated for PVNS at a single institution from 2001 to 2016. Inclusion criteria were patients below 20 years of age with surgical treatment of histologically proven PVNS of the knee...
June 18, 2018: Journal of Pediatric Orthopedics
Oğuzhan Fatih Baltacı, Şeyma Çolakoğlu, Gökçe Güllü Amuran, Neslihan Aydın, Mehmet Sarğın, Arzu Karabay, Temel Yılmaz, Ergül Berber
Background/aim: MODY3 associated with HNF1A is the most common form of MODY and is clinically misdiagnosed as type 1 diabetes due to similar clinical symptoms. This study aimed to analyze the role of HNF1A-regulated miRNAs as a biomarker in the diagnosis of MODY3. Materials and methods: MIN6 cells were transfected with the HNF1A cDNA expression vector for overexpression or with siRNA specific to HNF1A to silence its expression. The HNF1A-regulated miRNAs were determined by RNA-Seq of the total RNA extract. Expressions of the candidate miRNAs in blood samples of MODY3, type 1 diabetes, and type 2 diabetes patients and in healthy subjects were compared statistically by Mann-Whitney U tests...
June 14, 2018: Turkish Journal of Medical Sciences
Leena Jalota, D Richard Allison, Vinisha Prajapati, Jose J Vempilly, Vipul V Jain
OBJECTIVE: Fraction of exhaled nitric oxide (FENO ) has been proposed as a non-invasive biomarker for allergic inflammation seen in asthma. Many asthmatics in clinical practice have never had spirometry and recent data report misdiagnoses in patients with physician diagnosed (PD) asthma. The aim of this study was to assess the ability of FENO to discriminate between those with and without airflow obstruction (AO) among patients with PD-asthma. METHODS: Frequent exacerbators of PD-asthma (with 2 or more asthma exacerbations leading to emergency room visit or hospitalization within last 12 months) were enrolled...
June 18, 2018: Lung
Fibi Ninan, Ajay Kumar Mishra, Ajoy Oommen John, Ramya Iyadurai
Melioidosis well known as a 'great mimicker' is caused by Burkholderia pseudomallei. Even though majority of the patients present with acute infection, around 18 % can present as chronic infection. These latent foci of infection may reactivate to cause fulminant infection at a later date. Due to lack of clinical suspicion and good laboratory facility latent infections are often misdiagnosed and treated as tuberculosis. Chronic splenic granuloma is a rare manifestation of Melioidosis . Deep seated abscess requires atleast 4 weeks of intensive treatment with intravenous antibiotics...
January 2018: Journal of Family Medicine and Primary Care
Beenish Fayyaz
Acute eosinophilic pneumonia (AEP) is commonly misdiagnosed as infectious pneumonia due to presence of fever and radiological features. However, development of peripheral eosinophilia within days of presentation should raise the concern of AEP especially in previously heathy adults with history of recent tobacco smoking.
2018: Journal of Community Hospital Internal Medicine Perspectives
Cheryl Bushnell, Virginia J Howard, Lynda Lisabeth, Valeria Caso, Seana Gall, Dawn Kleindorfer, Seemant Chaturvedi, Tracy E Madsen, Stacie L Demel, Seung-Jae Lee, Mathew Reeves
With the greater availability of treatments for acute ischaemic stroke, including advances in endovascular therapy, personalised assessment of patients before treatment is more important than ever. Women have a higher lifetime risk of stroke; therefore, reducing potential sex differences in the acute stroke setting is crucial for the provision of equitable and fast treatment. Evidence indicates sex differences in prevalence and types of non-traditional stroke symptoms or signs, prevalence of stroke mimics, and door-to-imaging times, but no substantial differences in use of emergency medical services, stroke knowledge, eligibility for or access to thrombolysis or thrombectomy, or outcomes after either therapy...
July 2018: Lancet Neurology
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